FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE5201, 218 aa
  1>>>pF1KE5201 218 - 218 aa - 218 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.3583+/-0.000414; mu= 13.4030+/- 0.026
 mean_var=65.3421+/-13.282, 0's: 0 Z-trim(110.5): 21  B-trim: 0 in 0/51
 Lambda= 0.158664
 statistics sampled from 18870 (18885) to 18870 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.603), E-opt: 0.2 (0.221), width:  16
 Scan time:  5.810

The best scores are:                                      opt bits E(85289)
NP_000185 (OMIM: 300322,300323,308000) hypoxanthin ( 218) 1448 340.3 1.4e-93
NP_064585 (OMIM: 610751) phosphoribosyltransferase ( 225) 1009 239.8 2.6e-63
NP_001269715 (OMIM: 610751) phosphoribosyltransfer ( 190)  781 187.6 1.2e-47


>>NP_000185 (OMIM: 300322,300323,308000) hypoxanthine-gu  (218 aa)
 initn: 1448 init1: 1448 opt: 1448  Z-score: 1800.8  bits: 340.3 E(85289): 1.4e-93
Smith-Waterman score: 1448; 100.0% identity (100.0% similar) in 218 aa overlap (1-218:1-218)

               10        20        30        40        50        60
pF1KE5 MATRSPGVVISDDEPGYDLDLFCIPNHYAEDLERVFIPHGLIMDRTERLARDVMKEMGGH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MATRSPGVVISDDEPGYDLDLFCIPNHYAEDLERVFIPHGLIMDRTERLARDVMKEMGGH
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE5 HIVALCVLKGGYKFFADLLDYIKALNRNSDRSIPMTVDFIRLKSYCNDQSTGDIKVIGGD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 HIVALCVLKGGYKFFADLLDYIKALNRNSDRSIPMTVDFIRLKSYCNDQSTGDIKVIGGD
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE5 DLSTLTGKNVLIVEDIIDTGKTMQTLLSLVRQYNPKMVKVASLLVKRTPRSVGYKPDFVG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 DLSTLTGKNVLIVEDIIDTGKTMQTLLSLVRQYNPKMVKVASLLVKRTPRSVGYKPDFVG
              130       140       150       160       170       180

              190       200       210        
pF1KE5 FEIPDKFVVGYALDYNEYFRDLNHVCVISETGKAKYKA
       ::::::::::::::::::::::::::::::::::::::
NP_000 FEIPDKFVVGYALDYNEYFRDLNHVCVISETGKAKYKA
              190       200       210        

>>NP_064585 (OMIM: 610751) phosphoribosyltransferase dom  (225 aa)
 initn: 1025 init1: 1009 opt: 1009  Z-score: 1257.5  bits: 239.8 E(85289): 2.6e-63
Smith-Waterman score: 1009; 68.2% identity (88.2% similar) in 211 aa overlap (7-217:14-224)

                      10        20        30        40        50   
pF1KE5        MATRSPGVVISDDEPGYDLDLFCIPNHYAEDLERVFIPHGLIMDRTERLARDV
                    :::: :: :::::.::  :.::  ::: :.::::.:.:: ::::.:.
NP_064 MAGSSEEAPDYGRGVVIMDDWPGYDLNLFTYPQHYYGDLEYVLIPHGIIVDRIERLAKDI
               10        20        30        40        50        60

            60        70        80        90       100       110   
pF1KE5 MKEMGGHHIVALCVLKGGYKFFADLLDYIKALNRNSDRSIPMTVDFIRLKSYCNDQSTGD
       ::..:   :..:::::::::: :::....: ..::::: . : ::::::::: :::: :.
NP_064 MKDIGYSDIMVLCVLKGGYKFCADLVEHLKNISRNSDRFVSMKVDFIRLKSYRNDQSMGE
               70        80        90       100       110       120

           120       130       140       150       160       170   
pF1KE5 IKVIGGDDLSTLTGKNVLIVEDIIDTGKTMQTLLSLVRQYNPKMVKVASLLVKRTPRSVG
       ...:::::::::.:::::::::.. ::.::..::: ...:.:.:.:::::::::: :: :
NP_064 MQIIGGDDLSTLAGKNVLIVEDVVGTGRTMKALLSNIEKYKPNMIKVASLLVKRTSRSDG
              130       140       150       160       170       180

           180       190       200       210        
pF1KE5 YKPDFVGFEIPDKFVVGYALDYNEYFRDLNHVCVISETGKAKYKA
       ..::..:::::. ::::::::::::::::::.:::.: :: ::. 
NP_064 FRPDYAGFEIPNLFVVGYALDYNEYFRDLNHICVINEHGKEKYRV
              190       200       210       220     

>>NP_001269715 (OMIM: 610751) phosphoribosyltransferase   (190 aa)
 initn: 781 init1: 781 opt: 781  Z-score: 976.6  bits: 187.6 E(85289): 1.2e-47
Smith-Waterman score: 781; 66.1% identity (87.1% similar) in 171 aa overlap (7-177:14-184)

                      10        20        30        40        50   
pF1KE5        MATRSPGVVISDDEPGYDLDLFCIPNHYAEDLERVFIPHGLIMDRTERLARDV
                    :::: :: :::::.::  :.::  ::: :.::::.:.:: ::::.:.
NP_001 MAGSSEEAPDYGRGVVIMDDWPGYDLNLFTYPQHYYGDLEYVLIPHGIIVDRIERLAKDI
               10        20        30        40        50        60

            60        70        80        90       100       110   
pF1KE5 MKEMGGHHIVALCVLKGGYKFFADLLDYIKALNRNSDRSIPMTVDFIRLKSYCNDQSTGD
       ::..:   :..:::::::::: :::....: ..::::: . : ::::::::: :::: :.
NP_001 MKDIGYSDIMVLCVLKGGYKFCADLVEHLKNISRNSDRFVSMKVDFIRLKSYRNDQSMGE
               70        80        90       100       110       120

           120       130       140       150       160       170   
pF1KE5 IKVIGGDDLSTLTGKNVLIVEDIIDTGKTMQTLLSLVRQYNPKMVKVASLLVKRTPRSVG
       ...:::::::::.:::::::::.. ::.::..::: ...:.:.:.:::::::::: :: :
NP_001 MQIIGGDDLSTLAGKNVLIVEDVVGTGRTMKALLSNIEKYKPNMIKVASLLVKRTSRSDG
              130       140       150       160       170       180

           180       190       200       210        
pF1KE5 YKPDFVGFEIPDKFVVGYALDYNEYFRDLNHVCVISETGKAKYKA
       ..::                                         
NP_001 FRPDSHMRHQ                                   
              190                                   




218 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Mon Nov  7 22:27:48 2016 done: Mon Nov  7 22:27:49 2016
 Total Scan time:  5.810 Total Display time: -0.020

Function used was FASTA [36.3.4 Apr, 2011]