Result of FASTA (omim) for
pFN21AE5188
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE5188, 129 aa
1>>>pF1KE5188 129 - 129 aa - 129 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.8096+/-0.000272; mu= 13.5624+/- 0.017
mean_var=57.4807+/-11.499, 0's: 0 Z-trim(119.3): 25 B-trim: 357 in 1/53
Lambda= 0.169166
statistics sampled from 33244 (33269) to 33244 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.769), E-opt: 0.2 (0.39), width: 16
Scan time: 4.030
The best scores are: opt bits E(85289)
XP_011512836 (OMIM: 605450) PREDICTED: glutathione ( 185) 838 211.8 3.5e-55
XP_011512837 (OMIM: 605450) PREDICTED: glutathione ( 185) 838 211.8 3.5e-55
NP_001503 (OMIM: 605450) glutathione S-transferase ( 222) 838 211.9 4.1e-55
XP_005249092 (OMIM: 605450) PREDICTED: glutathione ( 222) 838 211.9 4.1e-55
XP_011512834 (OMIM: 138360) PREDICTED: glutathione ( 222) 412 107.9 8.1e-24
NP_000837 (OMIM: 138360) glutathione S-transferase ( 222) 412 107.9 8.1e-24
NP_001305988 (OMIM: 138359) glutathione S-transfer ( 129) 397 104.1 6.6e-23
XP_011512835 (OMIM: 605449) PREDICTED: glutathione ( 129) 395 103.6 9.2e-23
NP_665683 (OMIM: 138359) glutathione S-transferase ( 222) 397 104.2 1e-22
XP_006715135 (OMIM: 605449) PREDICTED: glutathione ( 172) 395 103.7 1.2e-22
XP_016866283 (OMIM: 605449) PREDICTED: glutathione ( 172) 395 103.7 1.2e-22
NP_000838 (OMIM: 605449) glutathione S-transferase ( 222) 395 103.7 1.4e-22
NP_714543 (OMIM: 607605) glutathione S-transferase ( 222) 377 99.4 3e-21
XP_005249091 (OMIM: 138359) PREDICTED: glutathione ( 225) 262 71.3 8.6e-13
NP_000843 (OMIM: 134660) glutathione S-transferase ( 210) 160 46.4 2.5e-05
>>XP_011512836 (OMIM: 605450) PREDICTED: glutathione S-t (185 aa)
initn: 838 init1: 838 opt: 838 Z-score: 1111.6 bits: 211.8 E(85289): 3.5e-55
Smith-Waterman score: 838; 100.0% identity (100.0% similar) in 129 aa overlap (1-129:57-185)
10 20 30
pF1KE5 MYVEGTLDLLELLIMHPFLKPDDQQKEVVN
::::::::::::::::::::::::::::::
XP_011 KLVQTRSILHYIADKHNLFGKNLKERTLIDMYVEGTLDLLELLIMHPFLKPDDQQKEVVN
30 40 50 60 70 80
40 50 60 70 80 90
pF1KE5 MAQKAIIRYFPVFEKILRGHGQSFLVGNQLSLADVILLQTILALEEKIPNILSAFPFLQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAQKAIIRYFPVFEKILRGHGQSFLVGNQLSLADVILLQTILALEEKIPNILSAFPFLQE
90 100 110 120 130 140
100 110 120
pF1KE5 YTVKLSNIPTIKRFLEPGSKKKPPPDEIYVRTVYNIFRP
:::::::::::::::::::::::::::::::::::::::
XP_011 YTVKLSNIPTIKRFLEPGSKKKPPPDEIYVRTVYNIFRP
150 160 170 180
>>XP_011512837 (OMIM: 605450) PREDICTED: glutathione S-t (185 aa)
initn: 838 init1: 838 opt: 838 Z-score: 1111.6 bits: 211.8 E(85289): 3.5e-55
Smith-Waterman score: 838; 100.0% identity (100.0% similar) in 129 aa overlap (1-129:57-185)
10 20 30
pF1KE5 MYVEGTLDLLELLIMHPFLKPDDQQKEVVN
::::::::::::::::::::::::::::::
XP_011 KLVQTRSILHYIADKHNLFGKNLKERTLIDMYVEGTLDLLELLIMHPFLKPDDQQKEVVN
30 40 50 60 70 80
40 50 60 70 80 90
pF1KE5 MAQKAIIRYFPVFEKILRGHGQSFLVGNQLSLADVILLQTILALEEKIPNILSAFPFLQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAQKAIIRYFPVFEKILRGHGQSFLVGNQLSLADVILLQTILALEEKIPNILSAFPFLQE
90 100 110 120 130 140
100 110 120
pF1KE5 YTVKLSNIPTIKRFLEPGSKKKPPPDEIYVRTVYNIFRP
:::::::::::::::::::::::::::::::::::::::
XP_011 YTVKLSNIPTIKRFLEPGSKKKPPPDEIYVRTVYNIFRP
150 160 170 180
>>NP_001503 (OMIM: 605450) glutathione S-transferase A4 (222 aa)
initn: 838 init1: 838 opt: 838 Z-score: 1110.5 bits: 211.9 E(85289): 4.1e-55
Smith-Waterman score: 838; 100.0% identity (100.0% similar) in 129 aa overlap (1-129:94-222)
10 20 30
pF1KE5 MYVEGTLDLLELLIMHPFLKPDDQQKEVVN
::::::::::::::::::::::::::::::
NP_001 KLVQTRSILHYIADKHNLFGKNLKERTLIDMYVEGTLDLLELLIMHPFLKPDDQQKEVVN
70 80 90 100 110 120
40 50 60 70 80 90
pF1KE5 MAQKAIIRYFPVFEKILRGHGQSFLVGNQLSLADVILLQTILALEEKIPNILSAFPFLQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAQKAIIRYFPVFEKILRGHGQSFLVGNQLSLADVILLQTILALEEKIPNILSAFPFLQE
130 140 150 160 170 180
100 110 120
pF1KE5 YTVKLSNIPTIKRFLEPGSKKKPPPDEIYVRTVYNIFRP
:::::::::::::::::::::::::::::::::::::::
NP_001 YTVKLSNIPTIKRFLEPGSKKKPPPDEIYVRTVYNIFRP
190 200 210 220
>>XP_005249092 (OMIM: 605450) PREDICTED: glutathione S-t (222 aa)
initn: 838 init1: 838 opt: 838 Z-score: 1110.5 bits: 211.9 E(85289): 4.1e-55
Smith-Waterman score: 838; 100.0% identity (100.0% similar) in 129 aa overlap (1-129:94-222)
10 20 30
pF1KE5 MYVEGTLDLLELLIMHPFLKPDDQQKEVVN
::::::::::::::::::::::::::::::
XP_005 KLVQTRSILHYIADKHNLFGKNLKERTLIDMYVEGTLDLLELLIMHPFLKPDDQQKEVVN
70 80 90 100 110 120
40 50 60 70 80 90
pF1KE5 MAQKAIIRYFPVFEKILRGHGQSFLVGNQLSLADVILLQTILALEEKIPNILSAFPFLQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MAQKAIIRYFPVFEKILRGHGQSFLVGNQLSLADVILLQTILALEEKIPNILSAFPFLQE
130 140 150 160 170 180
100 110 120
pF1KE5 YTVKLSNIPTIKRFLEPGSKKKPPPDEIYVRTVYNIFRP
:::::::::::::::::::::::::::::::::::::::
XP_005 YTVKLSNIPTIKRFLEPGSKKKPPPDEIYVRTVYNIFRP
190 200 210 220
>>XP_011512834 (OMIM: 138360) PREDICTED: glutathione S-t (222 aa)
initn: 412 init1: 412 opt: 412 Z-score: 548.6 bits: 107.9 E(85289): 8.1e-24
Smith-Waterman score: 412; 43.8% identity (78.1% similar) in 128 aa overlap (1-128:94-221)
10 20 30
pF1KE5 MYVEGTLDLLELLIMHPFLKPDDQQKEVVN
::.:: :: :.... :: .:..:. ...
XP_011 KLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQDAKLAL
70 80 90 100 110 120
40 50 60 70 80 90
pF1KE5 MAQKAIIRYFPVFEKILRGHGQSFLVGNQLSLADVILLQTILALEEKIPNILSAFPFLQE
. .:. ::::.:::.:..:::..::::.:: ::. :.. . .:: ...:.::.:.
XP_011 IQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPLLKA
130 140 150 160 170 180
100 110 120
pF1KE5 YTVKLSNIPTIKRFLEPGSKKKPPPDEIYVRTVYNIFRP
...::.::.:.::.::: .::: :: .. .:::
XP_011 LKTRISNLPTVKKFLQPGSPRKPPMDEKSLEESRKIFRF
190 200 210 220
>>NP_000837 (OMIM: 138360) glutathione S-transferase A2 (222 aa)
initn: 412 init1: 412 opt: 412 Z-score: 548.6 bits: 107.9 E(85289): 8.1e-24
Smith-Waterman score: 412; 43.8% identity (78.1% similar) in 128 aa overlap (1-128:94-221)
10 20 30
pF1KE5 MYVEGTLDLLELLIMHPFLKPDDQQKEVVN
::.:: :: :.... :: .:..:. ...
NP_000 KLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQDAKLAL
70 80 90 100 110 120
40 50 60 70 80 90
pF1KE5 MAQKAIIRYFPVFEKILRGHGQSFLVGNQLSLADVILLQTILALEEKIPNILSAFPFLQE
. .:. ::::.:::.:..:::..::::.:: ::. :.. . .:: ...:.::.:.
NP_000 IQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPLLKA
130 140 150 160 170 180
100 110 120
pF1KE5 YTVKLSNIPTIKRFLEPGSKKKPPPDEIYVRTVYNIFRP
...::.::.:.::.::: .::: :: .. .:::
NP_000 LKTRISNLPTVKKFLQPGSPRKPPMDEKSLEESRKIFRF
190 200 210 220
>>NP_001305988 (OMIM: 138359) glutathione S-transferase (129 aa)
initn: 397 init1: 397 opt: 397 Z-score: 532.3 bits: 104.1 E(85289): 6.6e-23
Smith-Waterman score: 397; 42.2% identity (76.6% similar) in 128 aa overlap (1-128:1-128)
10 20 30 40 50 60
pF1KE5 MYVEGTLDLLELLIMHPFLKPDDQQKEVVNMAQKAIIRYFPVFEKILRGHGQSFLVGNQL
::.:: :: :.... : :.... ... . .: ::::.:::.:..:::..::::.:
NP_001 MYIEGIADLGEMILLLPVCPPEEKDAKLALIKEKIKNRYFPAFEKVLKSHGQDYLVGNKL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 SLADVILLQTILALEEKIPNILSAFPFLQEYTVKLSNIPTIKRFLEPGSKKKPPPDEIYV
: ::. :.. . .:: ...:.::.:. ...::.::.:.::.::: .::: :: .
NP_001 SRADIHLVELLYYVEELDSSLISSFPLLKALKTRISNLPTVKKFLQPGSPRKPPMDEKSL
70 80 90 100 110 120
pF1KE5 RTVYNIFRP
. . .:::
NP_001 EEARKIFRF
>>XP_011512835 (OMIM: 605449) PREDICTED: glutathione S-t (129 aa)
initn: 395 init1: 395 opt: 395 Z-score: 529.6 bits: 103.6 E(85289): 9.2e-23
Smith-Waterman score: 395; 41.4% identity (77.3% similar) in 128 aa overlap (1-128:1-128)
10 20 30 40 50 60
pF1KE5 MYVEGTLDLLELLIMHPFLKPDDQQKEVVNMAQKAIIRYFPVFEKILRGHGQSFLVGNQL
::.:: :: :.... :. .:.... ... . .:. ::::.:::.:..:::..::::.:
XP_011 MYTEGMADLNEMILLLPLCRPEEKDAKIALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 SLADVILLQTILALEEKIPNILSAFPFLQEYTVKLSNIPTIKRFLEPGSKKKPPPDEIYV
: ::. :.. . .:: ...: ::.:. ...::.::.:.::.::: .::: : .
XP_011 SRADISLVELLYYVEELDSSLISNFPLLKALKTRISNLPTVKKFLQPGSPRKPPADAKAL
70 80 90 100 110 120
pF1KE5 RTVYNIFRP
. . .:::
XP_011 EEARKIFRF
>>NP_665683 (OMIM: 138359) glutathione S-transferase A1 (222 aa)
initn: 397 init1: 397 opt: 397 Z-score: 528.8 bits: 104.2 E(85289): 1e-22
Smith-Waterman score: 397; 42.2% identity (76.6% similar) in 128 aa overlap (1-128:94-221)
10 20 30
pF1KE5 MYVEGTLDLLELLIMHPFLKPDDQQKEVVN
::.:: :: :.... : :.... ...
NP_665 KLVQTRAILNYIASKYNLYGKDIKERALIDMYIEGIADLGEMILLLPVCPPEEKDAKLAL
70 80 90 100 110 120
40 50 60 70 80 90
pF1KE5 MAQKAIIRYFPVFEKILRGHGQSFLVGNQLSLADVILLQTILALEEKIPNILSAFPFLQE
. .: ::::.:::.:..:::..::::.:: ::. :.. . .:: ...:.::.:.
NP_665 IKEKIKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPLLKA
130 140 150 160 170 180
100 110 120
pF1KE5 YTVKLSNIPTIKRFLEPGSKKKPPPDEIYVRTVYNIFRP
...::.::.:.::.::: .::: :: .. . .:::
NP_665 LKTRISNLPTVKKFLQPGSPRKPPMDEKSLEEARKIFRF
190 200 210 220
>>XP_006715135 (OMIM: 605449) PREDICTED: glutathione S-t (172 aa)
initn: 395 init1: 395 opt: 395 Z-score: 527.8 bits: 103.7 E(85289): 1.2e-22
Smith-Waterman score: 395; 41.4% identity (77.3% similar) in 128 aa overlap (1-128:44-171)
10 20 30
pF1KE5 MYVEGTLDLLELLIMHPFLKPDDQQKEVVN
::.:: :: :.... :. .:.... ...
XP_006 KLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKDAKIAL
20 30 40 50 60 70
40 50 60 70 80 90
pF1KE5 MAQKAIIRYFPVFEKILRGHGQSFLVGNQLSLADVILLQTILALEEKIPNILSAFPFLQE
. .:. ::::.:::.:..:::..::::.:: ::. :.. . .:: ...: ::.:.
XP_006 IKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDSSLISNFPLLKA
80 90 100 110 120 130
100 110 120
pF1KE5 YTVKLSNIPTIKRFLEPGSKKKPPPDEIYVRTVYNIFRP
...::.::.:.::.::: .::: : .. . .:::
XP_006 LKTRISNLPTVKKFLQPGSPRKPPADAKALEEARKIFRF
140 150 160 170
129 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 22:24:57 2016 done: Mon Nov 7 22:24:57 2016
Total Scan time: 4.030 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]