Result of FASTA (omim) for
pFN21AE5187
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE5187, 136 aa
1>>>pF1KE5187 136 - 136 aa - 136 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.0537+/-0.000244; mu= 13.4039+/- 0.015
mean_var=68.0190+/-13.378, 0's: 0 Z-trim(122.0): 60 B-trim: 0 in 0/56
Lambda= 0.155510
statistics sampled from 39332 (39399) to 39332 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.829), E-opt: 0.2 (0.462), width: 16
Scan time: 4.340
The best scores are: opt bits E(85289)
NP_001238959 (OMIM: 603576,613216) transient recep ( 136) 950 220.7 5.8e-58
NP_002411 (OMIM: 603576,613216) transient receptor (1603) 518 124.5 6.1e-28
NP_001238953 (OMIM: 603576,613216) transient recep (1625) 518 124.5 6.2e-28
NP_001238949 (OMIM: 603576,613216) transient recep (1642) 518 124.5 6.2e-28
XP_016870650 (OMIM: 608961) PREDICTED: transient r (1106) 301 75.7 2.1e-13
XP_016870647 (OMIM: 608961) PREDICTED: transient r (1260) 301 75.8 2.3e-13
XP_016870646 (OMIM: 608961) PREDICTED: transient r (1315) 301 75.8 2.4e-13
XP_011517349 (OMIM: 608961) PREDICTED: transient r (1325) 301 75.8 2.4e-13
XP_016870642 (OMIM: 608961) PREDICTED: transient r (1327) 301 75.8 2.4e-13
XP_016870644 (OMIM: 608961) PREDICTED: transient r (1337) 301 75.8 2.4e-13
XP_016870640 (OMIM: 608961) PREDICTED: transient r (1339) 301 75.8 2.4e-13
XP_016870643 (OMIM: 608961) PREDICTED: transient r (1352) 301 75.8 2.4e-13
XP_016870639 (OMIM: 608961) PREDICTED: transient r (1352) 301 75.8 2.4e-13
XP_016870638 (OMIM: 608961) PREDICTED: transient r (1354) 301 75.8 2.4e-13
XP_016870641 (OMIM: 608961) PREDICTED: transient r (1362) 301 75.8 2.4e-13
XP_016870637 (OMIM: 608961) PREDICTED: transient r (1364) 301 75.8 2.4e-13
XP_011517348 (OMIM: 608961) PREDICTED: transient r (1697) 301 75.9 2.9e-13
XP_011517347 (OMIM: 608961) PREDICTED: transient r (1699) 301 75.9 2.9e-13
NP_001007472 (OMIM: 608961) transient receptor pot (1707) 301 75.9 2.9e-13
XP_011517346 (OMIM: 608961) PREDICTED: transient r (1709) 301 75.9 2.9e-13
XP_011517345 (OMIM: 608961) PREDICTED: transient r (1709) 301 75.9 2.9e-13
XP_011517344 (OMIM: 608961) PREDICTED: transient r (1711) 301 75.9 2.9e-13
XP_011517343 (OMIM: 608961) PREDICTED: transient r (1719) 301 75.9 2.9e-13
XP_011517342 (OMIM: 608961) PREDICTED: transient r (1721) 301 75.9 2.9e-13
XP_011517341 (OMIM: 608961) PREDICTED: transient r (1722) 301 75.9 2.9e-13
XP_016870632 (OMIM: 608961) PREDICTED: transient r (1724) 301 75.9 2.9e-13
XP_011517340 (OMIM: 608961) PREDICTED: transient r (1732) 301 75.9 2.9e-13
XP_016870631 (OMIM: 608961) PREDICTED: transient r (1734) 301 75.9 2.9e-13
XP_011517339 (OMIM: 608961) PREDICTED: transient r (1734) 301 75.9 2.9e-13
XP_016870630 (OMIM: 608961) PREDICTED: transient r (1736) 301 75.9 2.9e-13
XP_011517338 (OMIM: 608961) PREDICTED: transient r (1744) 301 75.9 2.9e-13
XP_011517337 (OMIM: 608961) PREDICTED: transient r (1746) 301 75.9 2.9e-13
XP_016877845 (OMIM: 105500,605692) PREDICTED: tran (1069) 180 48.6 3e-05
NP_001288141 (OMIM: 105500,605692) transient recep (1864) 180 48.7 4.6e-05
NP_060142 (OMIM: 105500,605692) transient receptor (1865) 180 48.7 4.6e-05
XP_016877842 (OMIM: 105500,605692) PREDICTED: tran (1873) 180 48.7 4.6e-05
XP_016877841 (OMIM: 105500,605692) PREDICTED: tran (1874) 180 48.7 4.6e-05
XP_005254543 (OMIM: 105500,605692) PREDICTED: tran (1885) 180 48.7 4.6e-05
XP_016877840 (OMIM: 105500,605692) PREDICTED: tran (1893) 180 48.7 4.7e-05
XP_016877839 (OMIM: 105500,605692) PREDICTED: tran (1894) 180 48.7 4.7e-05
XP_011516557 (OMIM: 602014,607009) PREDICTED: tran (1184) 152 42.3 0.0025
XP_016869778 (OMIM: 602014,607009) PREDICTED: tran (1560) 152 42.4 0.0031
XP_011516554 (OMIM: 602014,607009) PREDICTED: tran (1694) 152 42.4 0.0033
XP_016869777 (OMIM: 602014,607009) PREDICTED: tran (1852) 152 42.5 0.0036
XP_016869776 (OMIM: 602014,607009) PREDICTED: tran (1901) 152 42.5 0.0036
XP_011516552 (OMIM: 602014,607009) PREDICTED: tran (1930) 152 42.5 0.0037
XP_011516551 (OMIM: 602014,607009) PREDICTED: tran (1944) 152 42.5 0.0037
XP_011516550 (OMIM: 602014,607009) PREDICTED: tran (1975) 152 42.5 0.0038
XP_011516549 (OMIM: 602014,607009) PREDICTED: tran (1979) 152 42.5 0.0038
XP_011516548 (OMIM: 602014,607009) PREDICTED: tran (1981) 152 42.5 0.0038
>>NP_001238959 (OMIM: 603576,613216) transient receptor (136 aa)
initn: 950 init1: 950 opt: 950 Z-score: 1161.5 bits: 220.7 E(85289): 5.8e-58
Smith-Waterman score: 950; 99.3% identity (100.0% similar) in 136 aa overlap (1-136:1-136)
10 20 30 40 50 60
pF1KE5 MKDSNRCCCGQFTNQHIPPLPSATPSKNEEENKQVETQPEKWSVAKHTQSYPTDSYGVLE
:::::::::::::::::::::::::::::::.::::::::::::::::::::::::::::
NP_001 MKDSNRCCCGQFTNQHIPPLPSATPSKNEEESKQVETQPEKWSVAKHTQSYPTDSYGVLE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 FQGGGYSNKAMVRKAFRHGATRITAFIGGQSPSPKLQIPGLLHGCGSIFLDISLKNQEIY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FQGGGYSNKAMVRKAFRHGATRITAFIGGQSPSPKLQIPGLLHGCGSIFLDISLKNQEIY
70 80 90 100 110 120
130
pF1KE5 LCTWLLAMRLGNWTPL
::::::::::::::::
NP_001 LCTWLLAMRLGNWTPL
130
>>NP_002411 (OMIM: 603576,613216) transient receptor pot (1603 aa)
initn: 522 init1: 499 opt: 518 Z-score: 622.6 bits: 124.5 E(85289): 6.1e-28
Smith-Waterman score: 518; 60.9% identity (76.8% similar) in 138 aa overlap (1-133:1-134)
10 20 30 40 50 60
pF1KE5 MKDSNRCCCGQFTNQHIPPLPSATPSKNEEENKQVETQPEKWSVAKHTQSYPTDSYGVLE
:::::::::::::::::::::::::::::::.::::::::::::::::::::::::::::
NP_002 MKDSNRCCCGQFTNQHIPPLPSATPSKNEEESKQVETQPEKWSVAKHTQSYPTDSYGVLE
10 20 30 40 50 60
70 80 90 100 110
pF1KE5 FQGGGYSNKAM-VRKAFRHGATRITAFIGGQSPSPKLQIPGLL---HGCGSIFLDISLKN
::::::::::: .: .. :. ... . . .:..: :: :: : .... :
NP_002 FQGGGYSNKAMYIRVSYD---TKPDSLLHLMVKDWQLELPKLLISVHG-GLQNFEMQPKL
70 80 90 100 110
120 130
pF1KE5 QEIYLCTWL-LAMRLGNWTPL
.... . :: : :
NP_002 KQVFGKGLIKAAMTTGAWIFTGGVSTGVISHVGDALKDHSSKSRGRVCAIGIAPWGIVEN
120 130 140 150 160 170
>>NP_001238953 (OMIM: 603576,613216) transient receptor (1625 aa)
initn: 522 init1: 499 opt: 518 Z-score: 622.5 bits: 124.5 E(85289): 6.2e-28
Smith-Waterman score: 518; 60.9% identity (76.8% similar) in 138 aa overlap (1-133:23-156)
10 20 30
pF1KE5 MKDSNRCCCGQFTNQHIPPLPSATPSKNEEENKQVETQ
:::::::::::::::::::::::::::::::.::::::
NP_001 MGQKSWIEKTFCKRECIFVIPSMKDSNRCCCGQFTNQHIPPLPSATPSKNEEESKQVETQ
10 20 30 40 50 60
40 50 60 70 80 90
pF1KE5 PEKWSVAKHTQSYPTDSYGVLEFQGGGYSNKAM-VRKAFRHGATRITAFIGGQSPSPKLQ
::::::::::::::::::::::::::::::::: .: .. :. ... . . .:.
NP_001 PEKWSVAKHTQSYPTDSYGVLEFQGGGYSNKAMYIRVSYD---TKPDSLLHLMVKDWQLE
70 80 90 100 110
100 110 120 130
pF1KE5 IPGLL---HGCGSIFLDISLKNQEIYLCTWL-LAMRLGNWTPL
.: :: :: : .... : .... . :: : :
NP_001 LPKLLISVHG-GLQNFEMQPKLKQVFGKGLIKAAMTTGAWIFTGGVSTGVISHVGDALKD
120 130 140 150 160 170
NP_001 HSSKSRGRVCAIGIAPWGIVENKEDLVGKDVTRVYQTMSNPLSKLSVLNNSHTHFILADN
180 190 200 210 220 230
>>NP_001238949 (OMIM: 603576,613216) transient receptor (1642 aa)
initn: 522 init1: 499 opt: 518 Z-score: 622.5 bits: 124.5 E(85289): 6.2e-28
Smith-Waterman score: 518; 60.9% identity (76.8% similar) in 138 aa overlap (1-133:40-173)
10 20 30
pF1KE5 MKDSNRCCCGQFTNQHIPPLPSATPSKNEE
::::::::::::::::::::::::::::::
NP_001 KSSTSGSQKGQKSWIEKTFCKRECIFVIPSMKDSNRCCCGQFTNQHIPPLPSATPSKNEE
10 20 30 40 50 60
40 50 60 70 80
pF1KE5 ENKQVETQPEKWSVAKHTQSYPTDSYGVLEFQGGGYSNKAM-VRKAFRHGATRITAFIGG
:.::::::::::::::::::::::::::::::::::::::: .: .. :. ...
NP_001 ESKQVETQPEKWSVAKHTQSYPTDSYGVLEFQGGGYSNKAMYIRVSYD---TKPDSLLHL
70 80 90 100 110 120
90 100 110 120 130
pF1KE5 QSPSPKLQIPGLL---HGCGSIFLDISLKNQEIYLCTWL-LAMRLGNWTPL
. . .:..: :: :: : .... : .... . :: : :
NP_001 MVKDWQLELPKLLISVHG-GLQNFEMQPKLKQVFGKGLIKAAMTTGAWIFTGGVSTGVIS
130 140 150 160 170 180
NP_001 HVGDALKDHSSKSRGRVCAIGIAPWGIVENKEDLVGKDVTRVYQTMSNPLSKLSVLNNSH
190 200 210 220 230 240
>>XP_016870650 (OMIM: 608961) PREDICTED: transient recep (1106 aa)
initn: 217 init1: 194 opt: 301 Z-score: 361.8 bits: 75.7 E(85289): 2.1e-13
Smith-Waterman score: 301; 37.9% identity (65.7% similar) in 140 aa overlap (2-133:84-219)
10 20 30
pF1KE5 MKDSNRCCCGQFTNQHIPPLPSATPSKNEEE
:: .:::::.. .::. :: . .::..
XP_016 GLPSQQTPAQKSWIERAFYKRECVHIIPSTKDPHRCCCGRLIGQHVGLTPSISVLQNEKN
60 70 80 90 100 110
40 50 60 70 80
pF1KE5 NKQV---ETQPEKWSVAKHTQSYPTDSYGVLEFQGGGYSNKAM-VRKAFRHGATRITAFI
.... . : ::::..:::: :::..:..::::::.::::: :: .: :. ..
XP_016 ESRLSRNDIQSEKWSISKHTQLSPTDAFGTIEFQGGGHSNKAMYVRVSF---DTKPDLLL
120 130 140 150 160 170
90 100 110 120 130
pF1KE5 GGQSPSPKLQIPGLL---HGCGSIFLDISLKNQEIYLCTWL-LAMRLGNWTPL
.. .:..: :: :: : .... : .... . :: : :
XP_016 HLMTKEWQLELPKLLISVHG-GLQNFELQPKLKQVFGKGLIKAAMTTGAWIFTGGVNTGV
180 190 200 210 220
XP_016 IRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQTMSNPMSKLTVLNS
230 240 250 260 270 280
>>XP_016870647 (OMIM: 608961) PREDICTED: transient recep (1260 aa)
initn: 217 init1: 194 opt: 301 Z-score: 361.0 bits: 75.8 E(85289): 2.3e-13
Smith-Waterman score: 301; 37.9% identity (65.7% similar) in 140 aa overlap (2-133:82-217)
10 20 30
pF1KE5 MKDSNRCCCGQFTNQHIPPLPSATPSKNEEE
:: .:::::.. .::. :: . .::..
XP_016 LPSVRLLKAQKSWIERAFYKRECVHIIPSTKDPHRCCCGRLIGQHVGLTPSISVLQNEKN
60 70 80 90 100 110
40 50 60 70 80
pF1KE5 NKQV---ETQPEKWSVAKHTQSYPTDSYGVLEFQGGGYSNKAM-VRKAFRHGATRITAFI
.... . : ::::..:::: :::..:..::::::.::::: :: .: :. ..
XP_016 ESRLSRNDIQSEKWSISKHTQLSPTDAFGTIEFQGGGHSNKAMYVRVSF---DTKPDLLL
120 130 140 150 160
90 100 110 120 130
pF1KE5 GGQSPSPKLQIPGLL---HGCGSIFLDISLKNQEIYLCTWL-LAMRLGNWTPL
.. .:..: :: :: : .... : .... . :: : :
XP_016 HLMTKEWQLELPKLLISVHG-GLQNFELQPKLKQVFGKGLIKAAMTTGAWIFTGGVNTGV
170 180 190 200 210 220
XP_016 IRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQTMSNPMSKLTVLNS
230 240 250 260 270 280
>>XP_016870646 (OMIM: 608961) PREDICTED: transient recep (1315 aa)
initn: 217 init1: 194 opt: 301 Z-score: 360.7 bits: 75.8 E(85289): 2.4e-13
Smith-Waterman score: 301; 37.9% identity (65.7% similar) in 140 aa overlap (2-133:82-217)
10 20 30
pF1KE5 MKDSNRCCCGQFTNQHIPPLPSATPSKNEEE
:: .:::::.. .::. :: . .::..
XP_016 LPSVRLLKAQKSWIERAFYKRECVHIIPSTKDPHRCCCGRLIGQHVGLTPSISVLQNEKN
60 70 80 90 100 110
40 50 60 70 80
pF1KE5 NKQV---ETQPEKWSVAKHTQSYPTDSYGVLEFQGGGYSNKAM-VRKAFRHGATRITAFI
.... . : ::::..:::: :::..:..::::::.::::: :: .: :. ..
XP_016 ESRLSRNDIQSEKWSISKHTQLSPTDAFGTIEFQGGGHSNKAMYVRVSF---DTKPDLLL
120 130 140 150 160
90 100 110 120 130
pF1KE5 GGQSPSPKLQIPGLL---HGCGSIFLDISLKNQEIYLCTWL-LAMRLGNWTPL
.. .:..: :: :: : .... : .... . :: : :
XP_016 HLMTKEWQLELPKLLISVHG-GLQNFELQPKLKQVFGKGLIKAAMTTGAWIFTGGVNTGV
170 180 190 200 210 220
XP_016 IRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQTMSNPMSKLTVLNS
230 240 250 260 270 280
>>XP_011517349 (OMIM: 608961) PREDICTED: transient recep (1325 aa)
initn: 217 init1: 194 opt: 301 Z-score: 360.7 bits: 75.8 E(85289): 2.4e-13
Smith-Waterman score: 301; 37.9% identity (65.7% similar) in 140 aa overlap (2-133:82-217)
10 20 30
pF1KE5 MKDSNRCCCGQFTNQHIPPLPSATPSKNEEE
:: .:::::.. .::. :: . .::..
XP_011 LPSVRLLKAQKSWIERAFYKRECVHIIPSTKDPHRCCCGRLIGQHVGLTPSISVLQNEKN
60 70 80 90 100 110
40 50 60 70 80
pF1KE5 NKQV---ETQPEKWSVAKHTQSYPTDSYGVLEFQGGGYSNKAM-VRKAFRHGATRITAFI
.... . : ::::..:::: :::..:..::::::.::::: :: .: :. ..
XP_011 ESRLSRNDIQSEKWSISKHTQLSPTDAFGTIEFQGGGHSNKAMYVRVSF---DTKPDLLL
120 130 140 150 160
90 100 110 120 130
pF1KE5 GGQSPSPKLQIPGLL---HGCGSIFLDISLKNQEIYLCTWL-LAMRLGNWTPL
.. .:..: :: :: : .... : .... . :: : :
XP_011 HLMTKEWQLELPKLLISVHG-GLQNFELQPKLKQVFGKGLIKAAMTTGAWIFTGGVNTGV
170 180 190 200 210 220
XP_011 IRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQTMSNPMSKLTVLNS
230 240 250 260 270 280
>>XP_016870642 (OMIM: 608961) PREDICTED: transient recep (1327 aa)
initn: 217 init1: 194 opt: 301 Z-score: 360.7 bits: 75.8 E(85289): 2.4e-13
Smith-Waterman score: 301; 37.9% identity (65.7% similar) in 140 aa overlap (2-133:84-219)
10 20 30
pF1KE5 MKDSNRCCCGQFTNQHIPPLPSATPSKNEEE
:: .:::::.. .::. :: . .::..
XP_016 GLPSQQTPAQKSWIERAFYKRECVHIIPSTKDPHRCCCGRLIGQHVGLTPSISVLQNEKN
60 70 80 90 100 110
40 50 60 70 80
pF1KE5 NKQV---ETQPEKWSVAKHTQSYPTDSYGVLEFQGGGYSNKAM-VRKAFRHGATRITAFI
.... . : ::::..:::: :::..:..::::::.::::: :: .: :. ..
XP_016 ESRLSRNDIQSEKWSISKHTQLSPTDAFGTIEFQGGGHSNKAMYVRVSF---DTKPDLLL
120 130 140 150 160 170
90 100 110 120 130
pF1KE5 GGQSPSPKLQIPGLL---HGCGSIFLDISLKNQEIYLCTWL-LAMRLGNWTPL
.. .:..: :: :: : .... : .... . :: : :
XP_016 HLMTKEWQLELPKLLISVHG-GLQNFELQPKLKQVFGKGLIKAAMTTGAWIFTGGVNTGV
180 190 200 210 220
XP_016 IRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQTMSNPMSKLTVLNS
230 240 250 260 270 280
>>XP_016870644 (OMIM: 608961) PREDICTED: transient recep (1337 aa)
initn: 217 init1: 194 opt: 301 Z-score: 360.6 bits: 75.8 E(85289): 2.4e-13
Smith-Waterman score: 301; 37.9% identity (65.7% similar) in 140 aa overlap (2-133:82-217)
10 20 30
pF1KE5 MKDSNRCCCGQFTNQHIPPLPSATPSKNEEE
:: .:::::.. .::. :: . .::..
XP_016 LPSVRLLKAQKSWIERAFYKRECVHIIPSTKDPHRCCCGRLIGQHVGLTPSISVLQNEKN
60 70 80 90 100 110
40 50 60 70 80
pF1KE5 NKQV---ETQPEKWSVAKHTQSYPTDSYGVLEFQGGGYSNKAM-VRKAFRHGATRITAFI
.... . : ::::..:::: :::..:..::::::.::::: :: .: :. ..
XP_016 ESRLSRNDIQSEKWSISKHTQLSPTDAFGTIEFQGGGHSNKAMYVRVSF---DTKPDLLL
120 130 140 150 160
90 100 110 120 130
pF1KE5 GGQSPSPKLQIPGLL---HGCGSIFLDISLKNQEIYLCTWL-LAMRLGNWTPL
.. .:..: :: :: : .... : .... . :: : :
XP_016 HLMTKEWQLELPKLLISVHG-GLQNFELQPKLKQVFGKGLIKAAMTTGAWIFTGGVNTGV
170 180 190 200 210 220
XP_016 IRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQTMSNPMSKLTVLNS
230 240 250 260 270 280
136 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 22:24:30 2016 done: Mon Nov 7 22:24:31 2016
Total Scan time: 4.340 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]