Result of FASTA (omim) for
pFN21AE5116
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE5116, 147 aa
1>>>pF1KE5116 147 - 147 aa - 147 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.1079+/-0.000367; mu= 12.3397+/- 0.023
mean_var=58.2097+/-11.427, 0's: 0 Z-trim(113.9): 20 B-trim: 245 in 1/52
Lambda= 0.168103
statistics sampled from 23494 (23514) to 23494 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.672), E-opt: 0.2 (0.276), width: 16
Scan time: 4.470
The best scores are: opt bits E(85289)
NP_005321 (OMIM: 142100) hemoglobin subunit epsilo ( 147) 968 242.7 1.6e-64
NP_000175 (OMIM: 141749,142250,613977) hemoglobin ( 147) 810 204.4 5.6e-53
NP_000550 (OMIM: 141749,142200) hemoglobin subunit ( 147) 809 204.1 6.6e-53
NP_000509 (OMIM: 140700,141749,141900,603902,60390 ( 147) 774 195.6 2.4e-50
NP_000510 (OMIM: 142000) hemoglobin subunit delta ( 147) 754 190.8 6.9e-49
XP_005255345 (OMIM: 142310) PREDICTED: hemoglobin ( 142) 357 94.5 6.4e-20
NP_005323 (OMIM: 142310) hemoglobin subunit zeta [ ( 142) 357 94.5 6.4e-20
XP_005255344 (OMIM: 142310) PREDICTED: hemoglobin ( 154) 357 94.5 6.9e-20
NP_001003938 (OMIM: 609639) hemoglobin subunit mu ( 141) 332 88.4 4.3e-18
NP_000549 (OMIM: 140700,141800,604131,613978) hemo ( 142) 332 88.4 4.3e-18
NP_000508 (OMIM: 140700,141850,604131,613978) hemo ( 142) 332 88.4 4.3e-18
NP_005322 (OMIM: 142240) hemoglobin subunit theta- ( 142) 318 85.0 4.5e-17
NP_599030 (OMIM: 608759) cytoglobin [Homo sapiens] ( 190) 259 70.8 1.2e-12
XP_005257062 (OMIM: 608759) PREDICTED: cytoglobin ( 202) 259 70.8 1.2e-12
NP_005359 (OMIM: 160000) myoglobin [Homo sapiens] ( 154) 171 49.4 2.6e-06
XP_005261662 (OMIM: 160000) PREDICTED: myoglobin i ( 154) 171 49.4 2.6e-06
NP_976311 (OMIM: 160000) myoglobin [Homo sapiens] ( 154) 171 49.4 2.6e-06
NP_976312 (OMIM: 160000) myoglobin [Homo sapiens] ( 154) 171 49.4 2.6e-06
XP_016879605 (OMIM: 608759) PREDICTED: cytoglobin ( 137) 169 48.9 3.3e-06
NP_067080 (OMIM: 605304) neuroglobin [Homo sapiens ( 151) 159 46.5 1.9e-05
>>NP_005321 (OMIM: 142100) hemoglobin subunit epsilon [H (147 aa)
initn: 968 init1: 968 opt: 968 Z-score: 1279.2 bits: 242.7 E(85289): 1.6e-64
Smith-Waterman score: 968; 100.0% identity (100.0% similar) in 147 aa overlap (1-147:1-147)
10 20 30 40 50 60
pF1KE5 MVHFTAEEKAAVTSLWSKMNVEEAGGEALGRLLVVYPWTQRFFDSFGNLSSPSAILGNPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MVHFTAEEKAAVTSLWSKMNVEEAGGEALGRLLVVYPWTQRFFDSFGNLSSPSAILGNPK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 VKAHGKKVLTSFGDAIKNMDNLKPAFAKLSELHCDKLHVDPENFKLLGNVMVIILATHFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 VKAHGKKVLTSFGDAIKNMDNLKPAFAKLSELHCDKLHVDPENFKLLGNVMVIILATHFG
70 80 90 100 110 120
130 140
pF1KE5 KEFTPEVQAAWQKLVSAVAIALAHKYH
:::::::::::::::::::::::::::
NP_005 KEFTPEVQAAWQKLVSAVAIALAHKYH
130 140
>>NP_000175 (OMIM: 141749,142250,613977) hemoglobin subu (147 aa)
initn: 810 init1: 810 opt: 810 Z-score: 1072.1 bits: 204.4 E(85289): 5.6e-53
Smith-Waterman score: 810; 79.6% identity (94.6% similar) in 147 aa overlap (1-147:1-147)
10 20 30 40 50 60
pF1KE5 MVHFTAEEKAAVTSLWSKMNVEEAGGEALGRLLVVYPWTQRFFDSFGNLSSPSAILGNPK
: ::: :.::..::::.:.:::.::::.::::::::::::::::::::::: :::.::::
NP_000 MGHFTEEDKATITSLWGKVNVEDAGGETLGRLLVVYPWTQRFFDSFGNLSSASAIMGNPK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 VKAHGKKVLTSFGDAIKNMDNLKPAFAKLSELHCDKLHVDPENFKLLGNVMVIILATHFG
:::::::::::.:::::..:.:: .::.::::::::::::::::::::::.: .:: :::
NP_000 VKAHGKKVLTSLGDAIKHLDDLKGTFAQLSELHCDKLHVDPENFKLLGNVLVTVLAIHFG
70 80 90 100 110 120
130 140
pF1KE5 KEFTPEVQAAWQKLVSAVAIALAHKYH
:::::::::.:::.:..:: ::. .::
NP_000 KEFTPEVQASWQKMVTGVASALSSRYH
130 140
>>NP_000550 (OMIM: 141749,142200) hemoglobin subunit gam (147 aa)
initn: 809 init1: 809 opt: 809 Z-score: 1070.8 bits: 204.1 E(85289): 6.6e-53
Smith-Waterman score: 809; 79.6% identity (93.9% similar) in 147 aa overlap (1-147:1-147)
10 20 30 40 50 60
pF1KE5 MVHFTAEEKAAVTSLWSKMNVEEAGGEALGRLLVVYPWTQRFFDSFGNLSSPSAILGNPK
: ::: :.::..::::.:.:::.::::.::::::::::::::::::::::: :::.::::
NP_000 MGHFTEEDKATITSLWGKVNVEDAGGETLGRLLVVYPWTQRFFDSFGNLSSASAIMGNPK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 VKAHGKKVLTSFGDAIKNMDNLKPAFAKLSELHCDKLHVDPENFKLLGNVMVIILATHFG
:::::::::::.::: :..:.:: .::.::::::::::::::::::::::.: .:: :::
NP_000 VKAHGKKVLTSLGDATKHLDDLKGTFAQLSELHCDKLHVDPENFKLLGNVLVTVLAIHFG
70 80 90 100 110 120
130 140
pF1KE5 KEFTPEVQAAWQKLVSAVAIALAHKYH
:::::::::.:::.:.::: ::. .::
NP_000 KEFTPEVQASWQKMVTAVASALSSRYH
130 140
>>NP_000509 (OMIM: 140700,141749,141900,603902,603903,60 (147 aa)
initn: 774 init1: 774 opt: 774 Z-score: 1024.9 bits: 195.6 E(85289): 2.4e-50
Smith-Waterman score: 774; 75.5% identity (93.9% similar) in 147 aa overlap (1-147:1-147)
10 20 30 40 50 60
pF1KE5 MVHFTAEEKAAVTSLWSKMNVEEAGGEALGRLLVVYPWTQRFFDSFGNLSSPSAILGNPK
:::.: :::.:::.::.:.::.:.:::::::::::::::::::.:::.::.:.:..::::
NP_000 MVHLTPEEKSAVTALWGKVNVDEVGGEALGRLLVVYPWTQRFFESFGDLSTPDAVMGNPK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 VKAHGKKVLTSFGDAIKNMDNLKPAFAKLSELHCDKLHVDPENFKLLGNVMVIILATHFG
::::::::: .:.:.. ..:::: .:: ::::::::::::::::.:::::.: .:: :::
NP_000 VKAHGKKVLGAFSDGLAHLDNLKGTFATLSELHCDKLHVDPENFRLLGNVLVCVLAHHFG
70 80 90 100 110 120
130 140
pF1KE5 KEFTPEVQAAWQKLVSAVAIALAHKYH
::::: ::::.::.:..:: :::::::
NP_000 KEFTPPVQAAYQKVVAGVANALAHKYH
130 140
>>NP_000510 (OMIM: 142000) hemoglobin subunit delta [Hom (147 aa)
initn: 754 init1: 754 opt: 754 Z-score: 998.7 bits: 190.8 E(85289): 6.9e-49
Smith-Waterman score: 754; 72.8% identity (94.6% similar) in 147 aa overlap (1-147:1-147)
10 20 30 40 50 60
pF1KE5 MVHFTAEEKAAVTSLWSKMNVEEAGGEALGRLLVVYPWTQRFFDSFGNLSSPSAILGNPK
:::.: :::.::..::.:.::. .:::::::::::::::::::.:::.::::.:..::::
NP_000 MVHLTPEEKTAVNALWGKVNVDAVGGEALGRLLVVYPWTQRFFESFGDLSSPDAVMGNPK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 VKAHGKKVLTSFGDAIKNMDNLKPAFAKLSELHCDKLHVDPENFKLLGNVMVIILATHFG
::::::::: .:.:.. ..:::: .:..::::::::::::::::.:::::.: .:: .::
NP_000 VKAHGKKVLGAFSDGLAHLDNLKGTFSQLSELHCDKLHVDPENFRLLGNVLVCVLARNFG
70 80 90 100 110 120
130 140
pF1KE5 KEFTPEVQAAWQKLVSAVAIALAHKYH
:::::..:::.::.:..:: :::::::
NP_000 KEFTPQMQAAYQKVVAGVANALAHKYH
130 140
>>XP_005255345 (OMIM: 142310) PREDICTED: hemoglobin subu (142 aa)
initn: 287 init1: 287 opt: 357 Z-score: 478.6 bits: 94.5 E(85289): 6.4e-20
Smith-Waterman score: 357; 40.0% identity (75.9% similar) in 145 aa overlap (4-146:3-141)
10 20 30 40 50
pF1KE5 MVHFTAEEKAAVTSLWSKMNVEE--AGGEALGRLLVVYPWTQRFFDSFGNLSSPSAILGN
.: :.. ..:.:.:.... : :.: ::.. .: :. .: : .: : :.
XP_005 MSLTKTERTIIVSMWAKISTQADTIGTETLERLFLSHPQTKTYFPHF-DLH-P----GS
10 20 30 40 50
60 70 80 90 100 110
pF1KE5 PKVKAHGKKVLTSFGDAIKNMDNLKPAFAKLSELHCDKLHVDPENFKLLGNVMVIILATH
...:::.::... :::.:..:.. :..:::::: :.::: :::::.. ... ::..
XP_005 AQLRAHGSKVVAAVGDAVKSIDDIGGALSKLSELHAYILRVDPVNFKLLSHCLLVTLAAR
60 70 80 90 100 110
120 130 140
pF1KE5 FGKEFTPEVQAAWQKLVSAVAIALAHKYH
: .:: :..:::.:..:.:. .:..::
XP_005 FPADFTAEAHAAWDKFLSVVSSVLTEKYR
120 130 140
>>NP_005323 (OMIM: 142310) hemoglobin subunit zeta [Homo (142 aa)
initn: 287 init1: 287 opt: 357 Z-score: 478.6 bits: 94.5 E(85289): 6.4e-20
Smith-Waterman score: 357; 40.0% identity (75.9% similar) in 145 aa overlap (4-146:3-141)
10 20 30 40 50
pF1KE5 MVHFTAEEKAAVTSLWSKMNVEE--AGGEALGRLLVVYPWTQRFFDSFGNLSSPSAILGN
.: :.. ..:.:.:.... : :.: ::.. .: :. .: : .: : :.
NP_005 MSLTKTERTIIVSMWAKISTQADTIGTETLERLFLSHPQTKTYFPHF-DLH-P----GS
10 20 30 40 50
60 70 80 90 100 110
pF1KE5 PKVKAHGKKVLTSFGDAIKNMDNLKPAFAKLSELHCDKLHVDPENFKLLGNVMVIILATH
...:::.::... :::.:..:.. :..:::::: :.::: :::::.. ... ::..
NP_005 AQLRAHGSKVVAAVGDAVKSIDDIGGALSKLSELHAYILRVDPVNFKLLSHCLLVTLAAR
60 70 80 90 100 110
120 130 140
pF1KE5 FGKEFTPEVQAAWQKLVSAVAIALAHKYH
: .:: :..:::.:..:.:. .:..::
NP_005 FPADFTAEAHAAWDKFLSVVSSVLTEKYR
120 130 140
>>XP_005255344 (OMIM: 142310) PREDICTED: hemoglobin subu (154 aa)
initn: 287 init1: 287 opt: 357 Z-score: 478.1 bits: 94.5 E(85289): 6.9e-20
Smith-Waterman score: 357; 40.0% identity (75.9% similar) in 145 aa overlap (4-146:15-153)
10 20 30 40
pF1KE5 MVHFTAEEKAAVTSLWSKMNVEE--AGGEALGRLLVVYPWTQRFFDSFG
.: :.. ..:.:.:.... : :.: ::.. .: :. .: :
XP_005 MTCFFDAAHPAAMSLTKTERTIIVSMWAKISTQADTIGTETLERLFLSHPQTKTYFPHF-
10 20 30 40 50
50 60 70 80 90 100
pF1KE5 NLSSPSAILGNPKVKAHGKKVLTSFGDAIKNMDNLKPAFAKLSELHCDKLHVDPENFKLL
.: : :. ...:::.::... :::.:..:.. :..:::::: :.::: :::::
XP_005 DLH-P----GSAQLRAHGSKVVAAVGDAVKSIDDIGGALSKLSELHAYILRVDPVNFKLL
60 70 80 90 100 110
110 120 130 140
pF1KE5 GNVMVIILATHFGKEFTPEVQAAWQKLVSAVAIALAHKYH
.. ... ::..: .:: :..:::.:..:.:. .:..::
XP_005 SHCLLVTLAARFPADFTAEAHAAWDKFLSVVSSVLTEKYR
120 130 140 150
>>NP_001003938 (OMIM: 609639) hemoglobin subunit mu [Hom (141 aa)
initn: 293 init1: 259 opt: 332 Z-score: 445.9 bits: 88.4 E(85289): 4.3e-18
Smith-Waterman score: 332; 36.6% identity (74.5% similar) in 145 aa overlap (4-146:2-140)
10 20 30 40 50
pF1KE5 MVHFTAEEKAAVTSLWSKMNVEEA--GGEALGRLLVVYPWTQRFFDSFGNLSSPSAILGN
..:.:.: ....:. . .:: :.: : ::..::: :. .: .. .. . .:
NP_001 MLSAQERAQIAQVWDLIAGHEAQFGAELLLRLFTVYPSTKVYFPHLSACQDATQLL--
10 20 30 40 50
60 70 80 90 100 110
pF1KE5 PKVKAHGKKVLTSFGDAIKNMDNLKPAFAKLSELHCDKLHVDPENFKLLGNVMVIILATH
.::...:.. : :....:::. :.. :..:: :.::: :: :: . . ..::.:
NP_001 ----SHGQRMLAAVGAAVQHVDNLRAALSPLADLHALVLRVDPANFPLLIQCFHVVLASH
60 70 80 90 100 110
120 130 140
pF1KE5 FGKEFTPEVQAAWQKLVSAVAIALAHKYH
. ::: ..::::.:....::..:..::
NP_001 LQDEFTVQMQAAWDKFLTGVAVVLTEKYR
120 130 140
>>NP_000549 (OMIM: 140700,141800,604131,613978) hemoglob (142 aa)
initn: 264 init1: 264 opt: 332 Z-score: 445.8 bits: 88.4 E(85289): 4.3e-18
Smith-Waterman score: 332; 37.9% identity (72.4% similar) in 145 aa overlap (4-146:3-141)
10 20 30 40 50
pF1KE5 MVHFTAEEKAAVTSLWSKMNVE--EAGGEALGRLLVVYPWTQRFFDSFGNLSSPSAILGN
.. .:. : . :.:.... : :.::: :... .: :. .: : .:: :.
NP_000 MVLSPADKTNVKAAWGKVGAHAGEYGAEALERMFLSFPTTKTYFPHF-DLSH-----GS
10 20 30 40 50
60 70 80 90 100 110
pF1KE5 PKVKAHGKKVLTSFGDAIKNMDNLKPAFAKLSELHCDKLHVDPENFKLLGNVMVIILATH
.::.::::: .. .:. ..:.. :.. ::.:: ::.::: :::::.. ... ::.:
NP_000 AQVKGHGKKVADALTNAVAHVDDMPNALSALSDLHAHKLRVDPVNFKLLSHCLLVTLAAH
60 70 80 90 100 110
120 130 140
pF1KE5 FGKEFTPEVQAAWQKLVSAVAIALAHKYH
. :::: :.:. .:....:. .:. ::
NP_000 LPAEFTPAVHASLDKFLASVSTVLTSKYR
120 130 140
147 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 21:29:43 2016 done: Mon Nov 7 21:29:43 2016
Total Scan time: 4.470 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]