Result of FASTA (ccds) for
pFN21AE5055
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE5055, 197 aa
1>>>pF1KE5055 197 - 197 aa - 197 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.0617+/-0.000608; mu= 16.9719+/- 0.037
mean_var=89.8409+/-18.034, 0's: 0 Z-trim(114.1): 12 B-trim: 11 in 1/49
Lambda= 0.135312
statistics sampled from 14688 (14700) to 14688 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.793), E-opt: 0.2 (0.452), width: 16
Scan time: 2.350
The best scores are: opt bits E(32554)
CCDS12151.1 NRTN gene_id:4902|Hs108|chr19 ( 197) 1354 273.0 8.3e-74
CCDS75237.1 GDNF gene_id:2668|Hs108|chr5 ( 159) 336 74.2 4.7e-14
CCDS3923.1 GDNF gene_id:2668|Hs108|chr5 ( 185) 336 74.3 5.3e-14
CCDS54846.1 GDNF gene_id:2668|Hs108|chr5 ( 202) 336 74.3 5.6e-14
CCDS3922.1 GDNF gene_id:2668|Hs108|chr5 ( 211) 336 74.3 5.8e-14
CCDS54845.1 GDNF gene_id:2668|Hs108|chr5 ( 228) 336 74.3 6.1e-14
CCDS501.1 ARTN gene_id:9048|Hs108|chr1 ( 220) 330 73.2 1.3e-13
CCDS502.1 ARTN gene_id:9048|Hs108|chr1 ( 228) 330 73.2 1.4e-13
CCDS12164.1 PSPN gene_id:5623|Hs108|chr19 ( 156) 298 66.8 8e-12
>>CCDS12151.1 NRTN gene_id:4902|Hs108|chr19 (197 aa)
initn: 1354 init1: 1354 opt: 1354 Z-score: 1438.6 bits: 273.0 E(32554): 8.3e-74
Smith-Waterman score: 1354; 100.0% identity (100.0% similar) in 197 aa overlap (1-197:1-197)
10 20 30 40 50 60
pF1KE5 MQRWKAAALASVLCSSVLSIWMCREGLLLSHRLGPALVPLHRLPRTLDARIARLAQYRAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 MQRWKAAALASVLCSSVLSIWMCREGLLLSHRLGPALVPLHRLPRTLDARIARLAQYRAL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 LQGAPDAMELRELTPWAGRPPGPRRRAGPRRRRARARLGARPCGLRELEVRVSELGLGYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 LQGAPDAMELRELTPWAGRPPGPRRRAGPRRRRARARLGARPCGLRELEVRVSELGLGYA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 SDETVLFRYCAGACEAAARVYDLGLRRLRQRRRLRRERVRAQPCCRPTAYEDEVSFLDAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 SDETVLFRYCAGACEAAARVYDLGLRRLRQRRRLRRERVRAQPCCRPTAYEDEVSFLDAH
130 140 150 160 170 180
190
pF1KE5 SRYHTVHELSARECACV
:::::::::::::::::
CCDS12 SRYHTVHELSARECACV
190
>>CCDS75237.1 GDNF gene_id:2668|Hs108|chr5 (159 aa)
initn: 322 init1: 156 opt: 336 Z-score: 365.7 bits: 74.2 E(32554): 4.7e-14
Smith-Waterman score: 336; 41.7% identity (71.3% similar) in 115 aa overlap (87-197:46-159)
60 70 80 90 100 110
pF1KE5 YRALLQGAPDAMELRELTPWAGRPPGPRRRAGPRRRRARARLGARP----CGLRELEVRV
:.:. :...: : : : : ... :
CCDS75 IQATIKRLKRSPDKQMAVLPRRERNRQAAAANPENSRGKGRRGQRGKNRGCVLTAIHLNV
20 30 40 50 60 70
120 130 140 150 160 170
pF1KE5 SELGLGYASDETVLFRYCAGACEAAARVYDLGLRRLRQRRRLRRERVRAQPCCRPTAYED
..::::: . : ..::::.:.:.:: .:: :. : . ::: ..: .: :::: :..:
CCDS75 TDLGLGYETKEELIFRYCSGSCDAAETTYDKILKNLSRNRRLVSDKV-GQACCRPIAFDD
80 90 100 110 120 130
180 190
pF1KE5 EVSFLDAHSRYHTVHELSARECACV
..:::: . :: ... ::..:.:.
CCDS75 DLSFLDDNLVYHILRKHSAKRCGCI
140 150
>>CCDS3923.1 GDNF gene_id:2668|Hs108|chr5 (185 aa)
initn: 322 init1: 156 opt: 336 Z-score: 364.9 bits: 74.3 E(32554): 5.3e-14
Smith-Waterman score: 336; 41.7% identity (71.3% similar) in 115 aa overlap (87-197:72-185)
60 70 80 90 100 110
pF1KE5 YRALLQGAPDAMELRELTPWAGRPPGPRRRAGPRRRRARARLGARP----CGLRELEVRV
:.:. :...: : : : : ... :
CCDS39 IQATIKRLKRSPDKQMAVLPRRERNRQAAAANPENSRGKGRRGQRGKNRGCVLTAIHLNV
50 60 70 80 90 100
120 130 140 150 160 170
pF1KE5 SELGLGYASDETVLFRYCAGACEAAARVYDLGLRRLRQRRRLRRERVRAQPCCRPTAYED
..::::: . : ..::::.:.:.:: .:: :. : . ::: ..: .: :::: :..:
CCDS39 TDLGLGYETKEELIFRYCSGSCDAAETTYDKILKNLSRNRRLVSDKV-GQACCRPIAFDD
110 120 130 140 150 160
180 190
pF1KE5 EVSFLDAHSRYHTVHELSARECACV
..:::: . :: ... ::..:.:.
CCDS39 DLSFLDDNLVYHILRKHSAKRCGCI
170 180
>>CCDS54846.1 GDNF gene_id:2668|Hs108|chr5 (202 aa)
initn: 324 init1: 156 opt: 336 Z-score: 364.4 bits: 74.3 E(32554): 5.6e-14
Smith-Waterman score: 336; 41.7% identity (71.3% similar) in 115 aa overlap (87-197:89-202)
60 70 80 90 100 110
pF1KE5 YRALLQGAPDAMELRELTPWAGRPPGPRRRAGPRRRRARARLGARP----CGLRELEVRV
:.:. :...: : : : : ... :
CCDS54 IQATIKRLKRSPDKQMAVLPRRERNRQAAAANPENSRGKGRRGQRGKNRGCVLTAIHLNV
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE5 SELGLGYASDETVLFRYCAGACEAAARVYDLGLRRLRQRRRLRRERVRAQPCCRPTAYED
..::::: . : ..::::.:.:.:: .:: :. : . ::: ..: .: :::: :..:
CCDS54 TDLGLGYETKEELIFRYCSGSCDAAETTYDKILKNLSRNRRLVSDKV-GQACCRPIAFDD
120 130 140 150 160 170
180 190
pF1KE5 EVSFLDAHSRYHTVHELSARECACV
..:::: . :: ... ::..:.:.
CCDS54 DLSFLDDNLVYHILRKHSAKRCGCI
180 190 200
>>CCDS3922.1 GDNF gene_id:2668|Hs108|chr5 (211 aa)
initn: 321 init1: 156 opt: 336 Z-score: 364.2 bits: 74.3 E(32554): 5.8e-14
Smith-Waterman score: 336; 41.7% identity (71.3% similar) in 115 aa overlap (87-197:98-211)
60 70 80 90 100 110
pF1KE5 YRALLQGAPDAMELRELTPWAGRPPGPRRRAGPRRRRARARLGARP----CGLRELEVRV
:.:. :...: : : : : ... :
CCDS39 IQATIKRLKRSPDKQMAVLPRRERNRQAAAANPENSRGKGRRGQRGKNRGCVLTAIHLNV
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE5 SELGLGYASDETVLFRYCAGACEAAARVYDLGLRRLRQRRRLRRERVRAQPCCRPTAYED
..::::: . : ..::::.:.:.:: .:: :. : . ::: ..: .: :::: :..:
CCDS39 TDLGLGYETKEELIFRYCSGSCDAAETTYDKILKNLSRNRRLVSDKV-GQACCRPIAFDD
130 140 150 160 170 180
180 190
pF1KE5 EVSFLDAHSRYHTVHELSARECACV
..:::: . :: ... ::..:.:.
CCDS39 DLSFLDDNLVYHILRKHSAKRCGCI
190 200 210
>>CCDS54845.1 GDNF gene_id:2668|Hs108|chr5 (228 aa)
initn: 321 init1: 156 opt: 336 Z-score: 363.8 bits: 74.3 E(32554): 6.1e-14
Smith-Waterman score: 336; 41.7% identity (71.3% similar) in 115 aa overlap (87-197:115-228)
60 70 80 90 100 110
pF1KE5 YRALLQGAPDAMELRELTPWAGRPPGPRRRAGPRRRRARARLGARP----CGLRELEVRV
:.:. :...: : : : : ... :
CCDS54 IQATIKRLKRSPDKQMAVLPRRERNRQAAAANPENSRGKGRRGQRGKNRGCVLTAIHLNV
90 100 110 120 130 140
120 130 140 150 160 170
pF1KE5 SELGLGYASDETVLFRYCAGACEAAARVYDLGLRRLRQRRRLRRERVRAQPCCRPTAYED
..::::: . : ..::::.:.:.:: .:: :. : . ::: ..: .: :::: :..:
CCDS54 TDLGLGYETKEELIFRYCSGSCDAAETTYDKILKNLSRNRRLVSDKV-GQACCRPIAFDD
150 160 170 180 190 200
180 190
pF1KE5 EVSFLDAHSRYHTVHELSARECACV
..:::: . :: ... ::..:.:.
CCDS54 DLSFLDDNLVYHILRKHSAKRCGCI
210 220
>>CCDS501.1 ARTN gene_id:9048|Hs108|chr1 (220 aa)
initn: 353 init1: 159 opt: 330 Z-score: 357.6 bits: 73.2 E(32554): 1.3e-13
Smith-Waterman score: 330; 41.1% identity (53.1% similar) in 207 aa overlap (4-197:24-219)
10 20 30
pF1KE5 MQRWKA-AALASVLCSSVLSIWMCREGLLLSHRLGPALV-
: . :::: : ::: . . : :: :
CCDS50 MELGLGGLSTLSHCPWPRQQPALWPTLAALA--LLSSVAEASLGSAPRSPAPREGPPPVL
10 20 30 40 50
40 50 60 70 80 90
pF1KE5 --PLHRLPRTLDARIARLAQYRALLQGAPDAMELRELTPWAGRPPG--PR----RRAGPR
: .:: .: :: . :: : . : : . ::. :: :::
CCDS50 ASPAGHLP---GGRTARWCSGRAR---RPPPQPSRPAPPPPA-PPSALPRGGRAARAGGP
60 70 80 90 100 110
100 110 120 130 140 150
pF1KE5 RRRARARLGARPCGLRELEVRVSELGLGYASDETVLFRYCAGACEAAARVYDLGLRRLRQ
:::: ::: : :: : : ::::. ::: : ::.:.:.:. : .::.: :
CCDS50 GSRARAA-GARGCRLRSQLVPVRALGLGHRSDELVRFRFCSGSCRRARSPHDLSLASLLG
120 130 140 150 160 170
160 170 180 190
pF1KE5 RRRLRRE---RVRAQPCCRPTAYEDEVSFLDAHSRYHTVHELSARECACV
:: : .::::::: :: :::.:..: ..:: .::: :.:.
CCDS50 AGALRPPPGSRPVSQPCCRPTRYE-AVSFMDVNSTWRTVDRLSATACGCLG
180 190 200 210 220
>>CCDS502.1 ARTN gene_id:9048|Hs108|chr1 (228 aa)
initn: 353 init1: 159 opt: 330 Z-score: 357.5 bits: 73.2 E(32554): 1.4e-13
Smith-Waterman score: 330; 41.1% identity (53.1% similar) in 207 aa overlap (4-197:32-227)
10 20 30
pF1KE5 MQRWKA-AALASVLCSSVLSIWMCREGLLLSHR
: . :::: : ::: . . :
CCDS50 ELGLGGLSTLSHCPWPRQQAPLGLSAQPALWPTLAALA--LLSSVAEASLGSAPRSPAPR
10 20 30 40 50
40 50 60 70 80
pF1KE5 LGPALV---PLHRLPRTLDARIARLAQYRALLQGAPDAMELRELTPWAGRPPG--PR---
:: : : .:: .: :: . :: : . : : . ::. ::
CCDS50 EGPPPVLASPAGHLP---GGRTARWCSGRAR---RPPPQPSRPAPPPPA-PPSALPRGGR
60 70 80 90 100 110
90 100 110 120 130 140
pF1KE5 -RRAGPRRRRARARLGARPCGLRELEVRVSELGLGYASDETVLFRYCAGACEAAARVYDL
::: :::: ::: : :: : : ::::. ::: : ::.:.:.:. : .::
CCDS50 AARAGGPGSRARAA-GARGCRLRSQLVPVRALGLGHRSDELVRFRFCSGSCRRARSPHDL
120 130 140 150 160 170
150 160 170 180 190
pF1KE5 GLRRLRQRRRLRRE---RVRAQPCCRPTAYEDEVSFLDAHSRYHTVHELSARECACV
.: : :: : .::::::: :: :::.:..: ..:: .::: :.:.
CCDS50 SLASLLGAGALRPPPGSRPVSQPCCRPTRYE-AVSFMDVNSTWRTVDRLSATACGCLG
180 190 200 210 220
>>CCDS12164.1 PSPN gene_id:5623|Hs108|chr19 (156 aa)
initn: 323 init1: 168 opt: 298 Z-score: 325.7 bits: 66.8 E(32554): 8e-12
Smith-Waterman score: 298; 46.8% identity (68.5% similar) in 111 aa overlap (88-196:50-154)
60 70 80 90 100 110
pF1KE5 RALLQGAPDAMELRELTPWAGRPPGPRRRAGPRRRRARARLG-ARPCGLRELEVRVSELG
: .: :: : . . :: : : . :.:::
CCDS12 QGWGPDARGVPVADGEFSSEQVAKAGGTWLGTHRPLARLRRALSGPCQLWSLTLSVAELG
20 30 40 50 60 70
120 130 140 150 160 170
pF1KE5 LGYASDETVLFRYCAGACEAAARV-YDLGLRRLRQRRRLRRERVRAQPCCRPTAYEDEVS
:::::.: :.::::::.: .::. . :.: ::. . : ... :::::: : : :.
CCDS12 LGYASEEKVIFRYCAGSCPRGARTQHGLALARLQGQGR-----AHGGPCCRPTRYTD-VA
80 90 100 110 120 130
180 190
pF1KE5 FLDAHSRYHTVHELSARECACV
::: . :.. . .::: :.:
CCDS12 FLDDRHRWQRLPQLSAAACGCGG
140 150
197 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 04:35:26 2016 done: Tue Nov 8 04:35:26 2016
Total Scan time: 2.350 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]