FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE5054, 153 aa
  1>>>pF1KE5054 153 - 153 aa - 153 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 4.6391+/-0.000331; mu= 15.6359+/- 0.021
 mean_var=57.7766+/-11.607, 0's: 0 Z-trim(114.6): 17  B-trim: 0 in 0/55
 Lambda= 0.168732
 statistics sampled from 24561 (24571) to 24561 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.69), E-opt: 0.2 (0.288), width:  16
 Scan time:  4.270

The best scores are:                                      opt bits E(85289)
XP_011540180 (OMIM: 608057) PREDICTED: deoxyribonu ( 153) 1073 268.9 2.3e-72
NP_490649 (OMIM: 608057) deoxyribonuclease-2-beta  ( 153) 1073 268.9 2.3e-72
NP_067056 (OMIM: 608057) deoxyribonuclease-2-beta  ( 361) 1073 269.1 4.6e-72
NP_001366 (OMIM: 126350) deoxyribonuclease-2-alpha ( 360)  368 97.5 2.1e-20


>>XP_011540180 (OMIM: 608057) PREDICTED: deoxyribonuclea  (153 aa)
 initn: 1073 init1: 1073 opt: 1073  Z-score: 1420.1  bits: 268.9 E(85289): 2.3e-72
Smith-Waterman score: 1073; 100.0% identity (100.0% similar) in 153 aa overlap (1-153:1-153)

               10        20        30        40        50        60
pF1KE5 MPQLCTRASSSEIPGRLLTTLQSAQGQKFLHFAKSDSFLDDIFAAWMAQRLKTHLLTETW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MPQLCTRASSSEIPGRLLTTLQSAQGQKFLHFAKSDSFLDDIFAAWMAQRLKTHLLTETW
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE5 QRKRQELPSNCSLPYHVYNIKAIKLSRHSYFSSYQDHAKWCISQKGTKNRWTCIGDLNRS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QRKRQELPSNCSLPYHVYNIKAIKLSRHSYFSSYQDHAKWCISQKGTKNRWTCIGDLNRS
               70        80        90       100       110       120

              130       140       150   
pF1KE5 PHQAFRSGGFICTQNWQIYQAFQGLVLYYESCK
       :::::::::::::::::::::::::::::::::
XP_011 PHQAFRSGGFICTQNWQIYQAFQGLVLYYESCK
              130       140       150   

>>NP_490649 (OMIM: 608057) deoxyribonuclease-2-beta isof  (153 aa)
 initn: 1073 init1: 1073 opt: 1073  Z-score: 1420.1  bits: 268.9 E(85289): 2.3e-72
Smith-Waterman score: 1073; 100.0% identity (100.0% similar) in 153 aa overlap (1-153:1-153)

               10        20        30        40        50        60
pF1KE5 MPQLCTRASSSEIPGRLLTTLQSAQGQKFLHFAKSDSFLDDIFAAWMAQRLKTHLLTETW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_490 MPQLCTRASSSEIPGRLLTTLQSAQGQKFLHFAKSDSFLDDIFAAWMAQRLKTHLLTETW
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE5 QRKRQELPSNCSLPYHVYNIKAIKLSRHSYFSSYQDHAKWCISQKGTKNRWTCIGDLNRS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_490 QRKRQELPSNCSLPYHVYNIKAIKLSRHSYFSSYQDHAKWCISQKGTKNRWTCIGDLNRS
               70        80        90       100       110       120

              130       140       150   
pF1KE5 PHQAFRSGGFICTQNWQIYQAFQGLVLYYESCK
       :::::::::::::::::::::::::::::::::
NP_490 PHQAFRSGGFICTQNWQIYQAFQGLVLYYESCK
              130       140       150   

>>NP_067056 (OMIM: 608057) deoxyribonuclease-2-beta isof  (361 aa)
 initn: 1073 init1: 1073 opt: 1073  Z-score: 1414.8  bits: 269.1 E(85289): 4.6e-72
Smith-Waterman score: 1073; 100.0% identity (100.0% similar) in 153 aa overlap (1-153:209-361)

                                             10        20        30
pF1KE5                               MPQLCTRASSSEIPGRLLTTLQSAQGQKFL
                                     ::::::::::::::::::::::::::::::
NP_067 YEAIDSQLLVCNPNVYSCSIPATFHQELIHMPQLCTRASSSEIPGRLLTTLQSAQGQKFL
      180       190       200       210       220       230        

               40        50        60        70        80        90
pF1KE5 HFAKSDSFLDDIFAAWMAQRLKTHLLTETWQRKRQELPSNCSLPYHVYNIKAIKLSRHSY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_067 HFAKSDSFLDDIFAAWMAQRLKTHLLTETWQRKRQELPSNCSLPYHVYNIKAIKLSRHSY
      240       250       260       270       280       290        

              100       110       120       130       140       150
pF1KE5 FSSYQDHAKWCISQKGTKNRWTCIGDLNRSPHQAFRSGGFICTQNWQIYQAFQGLVLYYE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_067 FSSYQDHAKWCISQKGTKNRWTCIGDLNRSPHQAFRSGGFICTQNWQIYQAFQGLVLYYE
      300       310       320       330       340       350        

          
pF1KE5 SCK
       :::
NP_067 SCK
      360 

>>NP_001366 (OMIM: 126350) deoxyribonuclease-2-alpha pre  (360 aa)
 initn: 272 init1: 150 opt: 368  Z-score: 487.3  bits: 97.5 E(85289): 2.1e-20
Smith-Waterman score: 368; 39.6% identity (63.2% similar) in 144 aa overlap (11-152:207-347)

                                   10        20        30        40
pF1KE5                     MPQLCTRASSSEIPGRLLTTLQSAQGQKFLHFAKSDSFLD
                                     :. :     :: :  :  :  ::: ..: :
NP_001 TYPWVYNYQLEGIFAQEFPDLENVVKGHHVSQEPWNSSITLTSQAGAVFQSFAKFSKFGD
        180       190       200       210       220       230      

               50        60        70        80          90        
pF1KE5 DIFAAWMAQRLKTHLLTETWQRKRQELPSNCSLPYHVYNIKAIKLSRHS--YFSSYQDHA
       :....:.:  : :.: .. :..    ::::::  ..: :.. : .   .   :.: .::.
NP_001 DLYSGWLAAALGTNLQVQFWHKTVGILPSNCSDIWQVLNVNQIAFPGPAGPSFNSTEDHS
        240       250       260       270       280       290      

      100       110       120       130       140       150        
pF1KE5 KWCISQKGTKNRWTCIGDLNRSPHQAFRSGGFICTQNWQIYQAFQGLVLYYESCK     
       :::.: ::    :::.::.::.  .  :.:: .:.:   ...::: ::  :. :      
NP_001 KWCVSPKGP---WTCVGDMNRNQGEEQRGGGTLCAQLPALWKAFQPLVKNYQPCNGMARK
        300          310       320       330       340       350   

NP_001 PSRAYKI
           360




153 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Tue Nov  8 04:34:55 2016 done: Tue Nov  8 04:34:55 2016
 Total Scan time:  4.270 Total Display time: -0.040

Function used was FASTA [36.3.4 Apr, 2011]