FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE5008, 335 aa
  1>>>pF1KE5008 335 - 335 aa - 335 aa
Library: human.CCDS.faa
  18511270 residues in 32554 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 10.2984+/-0.00108; mu= -5.2906+/- 0.064
 mean_var=297.8652+/-61.606, 0's: 0 Z-trim(112.5): 22  B-trim: 99 in 2/52
 Lambda= 0.074313
 statistics sampled from 13277 (13288) to 13277 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.743), E-opt: 0.2 (0.408), width:  16
 Scan time:  3.110

The best scores are:                                      opt bits E(32554)
CCDS10564.1 NDE1 gene_id:54820|Hs108|chr16         ( 335) 2144 242.9 2.8e-64
CCDS32564.1 NDEL1 gene_id:81565|Hs108|chr17        ( 328) 1133 134.5 1.2e-31
CCDS11143.1 NDEL1 gene_id:81565|Hs108|chr17        ( 345) 1133 134.5 1.2e-31
CCDS82070.1 NDEL1 gene_id:81565|Hs108|chr17        ( 269) 1046 125.1 6.4e-29


>>CCDS10564.1 NDE1 gene_id:54820|Hs108|chr16              (335 aa)
 initn: 2144 init1: 2144 opt: 2144  Z-score: 1267.6  bits: 242.9 E(32554): 2.8e-64
Smith-Waterman score: 2144; 100.0% identity (100.0% similar) in 335 aa overlap (1-335:1-335)

               10        20        30        40        50        60
pF1KE5 MEDSGKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 MEDSGKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETR
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE5 NRDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 NRDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQA
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE5 NDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 NDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQEL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE5 AVQQKQEKPRTPMPSSVEAERTDTAVQATGSVPSTPIAHRGPSSSLNTPGSFRRGLDDST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 AVQQKQEKPRTPMPSSVEAERTDTAVQATGSVPSTPIAHRGPSSSLNTPGSFRRGLDDST
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE5 GGTPLTPAARISALNIVGDLLRKVGALESKLASCRNLVYDQSPNRTGGPASGRSSKNRDG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 GGTPLTPAARISALNIVGDLLRKVGALESKLASCRNLVYDQSPNRTGGPASGRSSKNRDG
              250       260       270       280       290       300

              310       320       330     
pF1KE5 GERRPSSTSVPLGDKGLDTSCRWLSKSTTRSSSSC
       :::::::::::::::::::::::::::::::::::
CCDS10 GERRPSSTSVPLGDKGLDTSCRWLSKSTTRSSSSC
              310       320       330     

>>CCDS32564.1 NDEL1 gene_id:81565|Hs108|chr17             (328 aa)
 initn: 1134 init1: 836 opt: 1133  Z-score: 682.0  bits: 134.5 E(32554): 1.2e-31
Smith-Waterman score: 1133; 59.4% identity (81.9% similar) in 315 aa overlap (8-316:9-315)

                10        20        30        40        50         
pF1KE5  MEDSGKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIET
               ::: .::. :::.:.. :::  .....:: :::::::: :::::.:: : : 
CCDS32 MDGEDIPDFSSLKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQ
               10        20        30        40        50        60

      60        70        80        90       100       110         
pF1KE5 RNRDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQ
       ::::: ..:.::..:.:..:::.: :....:.:.:.:::::.::.:::.::.::.:::::
CCDS32 RNRDLQADNQRLKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQ
               70        80        90       100       110       120

     120       130       140       150       160       170         
pF1KE5 ANDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQE
       :::::::::::::.:::::::::::::::::::::::::::.:: :::::::::::::::
CCDS32 ANDDLERAKRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQE
              130       140       150       160       170       180

     180        190         200       210       220       230      
pF1KE5 LAVQQKQEK-PRTPMPSS--VEAERTDTAVQATGSVPSTPIAHRGPSSSLNTPGSFRRGL
       :::...:..  :   :::  .. :. :.::::. :.:.::.. .:  ... .:    ...
CCDS32 LAVRERQQEVTRKSAPSSPTLDCEKMDSAVQASLSLPATPVG-KGTENTFPSP----KAI
              190       200       210       220        230         

        240       250       260       270       280          290   
pF1KE5 DDSTGGTPLTPAARISALNIVGDLLRKVGALESKLASCRNLVYDQSPNRT---GGPASGR
        .. : .::::.::::::::::::::::::::::::.:::.. ::.  ..   :.   : 
CCDS32 PNGFGTSPLTPSARISALNIVGDLLRKVGALESKLAACRNFAKDQASRKSYISGNVNCGV
         240       250       260       270       280       290     

           300       310       320       330     
pF1KE5 SSKNRDGGERRPSSTSVPLGDKGLDTSCRWLSKSTTRSSSSC
        . :   : .   :  . . :::                   
CCDS32 LNGN---GTKFSRSGHTSFFDKGQEKVIFPTLFMGQ      
            300       310       320              

>>CCDS11143.1 NDEL1 gene_id:81565|Hs108|chr17             (345 aa)
 initn: 1134 init1: 836 opt: 1133  Z-score: 681.7  bits: 134.5 E(32554): 1.2e-31
Smith-Waterman score: 1133; 59.4% identity (81.9% similar) in 315 aa overlap (8-316:9-315)

                10        20        30        40        50         
pF1KE5  MEDSGKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIET
               ::: .::. :::.:.. :::  .....:: :::::::: :::::.:: : : 
CCDS11 MDGEDIPDFSSLKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQ
               10        20        30        40        50        60

      60        70        80        90       100       110         
pF1KE5 RNRDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQ
       ::::: ..:.::..:.:..:::.: :....:.:.:.:::::.::.:::.::.::.:::::
CCDS11 RNRDLQADNQRLKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQ
               70        80        90       100       110       120

     120       130       140       150       160       170         
pF1KE5 ANDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQE
       :::::::::::::.:::::::::::::::::::::::::::.:: :::::::::::::::
CCDS11 ANDDLERAKRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQE
              130       140       150       160       170       180

     180        190         200       210       220       230      
pF1KE5 LAVQQKQEK-PRTPMPSS--VEAERTDTAVQATGSVPSTPIAHRGPSSSLNTPGSFRRGL
       :::...:..  :   :::  .. :. :.::::. :.:.::.. .:  ... .:    ...
CCDS11 LAVRERQQEVTRKSAPSSPTLDCEKMDSAVQASLSLPATPVG-KGTENTFPSP----KAI
              190       200       210       220        230         

        240       250       260       270       280          290   
pF1KE5 DDSTGGTPLTPAARISALNIVGDLLRKVGALESKLASCRNLVYDQSPNRT---GGPASGR
        .. : .::::.::::::::::::::::::::::::.:::.. ::.  ..   :.   : 
CCDS11 PNGFGTSPLTPSARISALNIVGDLLRKVGALESKLAACRNFAKDQASRKSYISGNVNCGV
         240       250       260       270       280       290     

           300       310       320       330                
pF1KE5 SSKNRDGGERRPSSTSVPLGDKGLDTSCRWLSKSTTRSSSSC           
        . :   : .   :  . . :::                              
CCDS11 LNGN---GTKFSRSGHTSFFDKGAVNGFDPAPPPPGLGSSRPSSAPGMLPLSV
            300       310       320       330       340     

>>CCDS82070.1 NDEL1 gene_id:81565|Hs108|chr17             (269 aa)
 initn: 1079 init1: 836 opt: 1046  Z-score: 632.7  bits: 125.1 E(32554): 6.4e-29
Smith-Waterman score: 1046; 64.4% identity (86.6% similar) in 261 aa overlap (8-265:9-264)

                10        20        30        40        50         
pF1KE5  MEDSGKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIET
               ::: .::. :::.:.. :::  .....:: :::::::: :::::.:: : : 
CCDS82 MDGEDIPDFSSLKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQ
               10        20        30        40        50        60

      60        70        80        90       100       110         
pF1KE5 RNRDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQ
       ::::: ..:.::..:.:..:::.: :....:.:.:.:::::.::.:::.::.::.:::::
CCDS82 RNRDLQADNQRLKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQ
               70        80        90       100       110       120

     120       130       140       150       160       170         
pF1KE5 ANDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQE
       :::::::::::::.:::::::::::::::::::::::::::.:: :::::::::::::::
CCDS82 ANDDLERAKRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQE
              130       140       150       160       170       180

     180        190         200       210       220       230      
pF1KE5 LAVQQKQEK-PRTPMPSS--VEAERTDTAVQATGSVPSTPIAHRGPSSSLNTPGSFRRGL
       :::...:..  :   :::  .. :. :.::::. :.:.::.. .:  ... .: ..  :.
CCDS82 LAVRERQQEVTRKSAPSSPTLDCEKMDSAVQASLSLPATPVG-KGTENTFPSPKAIPNGF
              190       200       210       220        230         

        240       250       260       270       280       290      
pF1KE5 DDSTGGTPLTPAARISALNIVGDLLRKVGALESKLASCRNLVYDQSPNRTGGPASGRSSK
           : .::::.:::::::::::::::::                               
CCDS82 ----GTSPLTPSARISALNIVGDLLRKVGGSKRL                          
         240       250       260                                   




335 residues in 1 query   sequences
18511270 residues in 32554 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Tue Nov  8 04:06:46 2016 done: Tue Nov  8 04:06:47 2016
 Total Scan time:  3.110 Total Display time:  0.010

Function used was FASTA [36.3.4 Apr, 2011]