Result of FASTA (omim) for
pFN21AE5002
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE5002, 636 aa
1>>>pF1KE5002 636 - 636 aa - 636 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.3469+/-0.000329; mu= 15.4759+/- 0.021
mean_var=90.1765+/-17.881, 0's: 0 Z-trim(116.6): 26 B-trim: 69 in 1/55
Lambda= 0.135060
statistics sampled from 27839 (27864) to 27839 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.669), E-opt: 0.2 (0.327), width: 16
Scan time: 9.790
The best scores are: opt bits E(85289)
NP_064529 (OMIM: 607436) poly(A) polymerase beta [ ( 637) 4169 822.4 0
XP_005267339 (OMIM: 605553) PREDICTED: poly(A) pol ( 699) 3519 695.8 1.3e-199
XP_005267338 (OMIM: 605553) PREDICTED: poly(A) pol ( 724) 3519 695.8 1.4e-199
NP_116021 (OMIM: 605553) poly(A) polymerase alpha ( 745) 3519 695.8 1.4e-199
XP_016876425 (OMIM: 605553) PREDICTED: poly(A) pol ( 698) 3500 692.1 1.8e-198
XP_016876424 (OMIM: 605553) PREDICTED: poly(A) pol ( 723) 3500 692.1 1.8e-198
NP_001280556 (OMIM: 605553) poly(A) polymerase alp ( 744) 3500 692.1 1.9e-198
XP_005264557 (OMIM: 616865) PREDICTED: poly(A) pol ( 714) 2539 504.8 4.2e-142
NP_075045 (OMIM: 616865) poly(A) polymerase gamma ( 736) 2539 504.8 4.3e-142
XP_005264558 (OMIM: 616865) PREDICTED: poly(A) pol ( 692) 2430 483.6 1e-135
NP_001280557 (OMIM: 605553) poly(A) polymerase alp ( 495) 1987 397.2 7.3e-110
NP_001280561 (OMIM: 605553) poly(A) polymerase alp ( 495) 1987 397.2 7.3e-110
NP_001238935 (OMIM: 605553) poly(A) polymerase alp ( 285) 1711 343.3 7e-94
XP_016860213 (OMIM: 616865) PREDICTED: poly(A) pol ( 476) 1428 288.3 4.3e-77
XP_011531343 (OMIM: 616865) PREDICTED: poly(A) pol ( 498) 1428 288.3 4.5e-77
XP_016860212 (OMIM: 616865) PREDICTED: poly(A) pol ( 498) 1428 288.3 4.5e-77
NP_001238936 (OMIM: 605553) poly(A) polymerase alp ( 238) 1234 250.3 5.7e-66
>>NP_064529 (OMIM: 607436) poly(A) polymerase beta [Homo (637 aa)
initn: 4169 init1: 4169 opt: 4169 Z-score: 4389.5 bits: 822.4 E(85289): 0
Smith-Waterman score: 4169; 99.5% identity (100.0% similar) in 636 aa overlap (1-636:2-637)
10 20 30 40 50
pF1KE5 MPFPVTTQGPPQPAPPPNRYGVSSPISLAVPKETDCLLTQRLIETLRPFGVFEEEEELQ
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 MMPFPVTTQGPPQPAPPPNRYGVSSPISLAVPKETDCLLTQRLIETLRPFGVFEEEEELQ
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE5 RRILVLDKLNNLVKEWIREISESKSLPQSVIENVGGKIFTFGSYRLGVHTKGADIDALCV
::::::.:::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 RRILVLEKLNNLVKEWIREISESKSLPQSVIENVGGKIFTFGSYRLGVHTKGADIDALCV
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE5 APSHVDRSDFFTSFYAKLKLQEEVKDLRAVQEAFVPVIKLCFDGIEIDILFARLALQTIP
::::::::::::::::::::::::::::::.:::::::::::::::::::::::::::::
NP_064 APSHVDRSDFFTSFYAKLKLQEEVKDLRAVEEAFVPVIKLCFDGIEIDILFARLALQTIP
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE5 EDLDLRDDSLLKNLDIRCIRSLNGCRVTDEILHLVPNIDNFRLTLRAIKLWAKCHNIYSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 EDLDLRDDSLLKNLDIRCIRSLNGCRVTDEILHLVPNIDNFRLTLRAIKLWAKCHNIYSN
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE5 ILGFLGGVSWAMLVARTCQLYPNAVASTLVRKFFLVFSEWEWPNPVLLKEPEERNLNLPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 ILGFLGGVSWAMLVARTCQLYPNAVASTLVRKFFLVFSEWEWPNPVLLKEPEERNLNLPV
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE5 WDPRVNPSDRYHLMPIITPAYPQQNSTYNVSISTRMVMIEEFKQGLAITHEILLSKAEWS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 WDPRVNPSDRYHLMPIITPAYPQQNSTYNVSISTRMVMIEEFKQGLAITHEILLSKAEWS
310 320 330 340 350 360
360 370 380 390 400 410
pF1KE5 KLFEAPSFFQKYKHYIVLLASASTEKQHLEWVGLVESKIRILVGSLEKNEFITLAHVNPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 KLFEAPSFFQKYKHYIVLLASASTEKQHLEWVGLVESKIRILVGSLEKNEFITLAHVNPQ
370 380 390 400 410 420
420 430 440 450 460 470
pF1KE5 SFPAPKENPDMEEFRTMWVIGLGLKKPDNSEILSIDLTYDIQSFTDTVYRQAVNSKMFEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 SFPAPKENPDMEEFRTMWVIGLGLKKPDNSEILSIDLTYDIQSFTDTVYRQAVNSKMFEM
430 440 450 460 470 480
480 490 500 510 520 530
pF1KE5 GMKITAVHLRRKELHQLLPHHVLQDKKAHSTEGRRLTDLNDSSFDLSAGCENSMSVPSST
::::::.:::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 GMKITAMHLRRKELHQLLPHHVLQDKKAHSTEGRRLTDLNDSSFDLSAGCENSMSVPSST
490 500 510 520 530 540
540 550 560 570 580 590
pF1KE5 STMKTGPLISSSQGRNSPALAVMTASVANIQATEFSLQQVNTNESSGVALNESIPHAVSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 STMKTGPLISSSQGRNSPALAVMTASVANIQATEFSLQQVNTNESSGVALNESIPHAVSQ
550 560 570 580 590 600
600 610 620 630
pF1KE5 PAISPSPKAMVARVVSSTCLISHPDLQETQQQTYLIL
:::::::::::::::::::::::::::::::::::::
NP_064 PAISPSPKAMVARVVSSTCLISHPDLQETQQQTYLIL
610 620 630
>>XP_005267339 (OMIM: 605553) PREDICTED: poly(A) polymer (699 aa)
initn: 3525 init1: 3245 opt: 3519 Z-score: 3704.4 bits: 695.8 E(85289): 1.3e-199
Smith-Waterman score: 3519; 85.8% identity (93.6% similar) in 625 aa overlap (1-623:1-625)
10 20 30 40 50 60
pF1KE5 MPFPVTTQGPPQPAPPPNRYGVSSPISLAVPKETDCLLTQRLIETLRPFGVFEEEEELQR
::::::::: : :: ..::..::::::.::::::.:::.:::::.:::::::::::::
XP_005 MPFPVTTQGSQQTQPPQKHYGITSPISLAAPKETDCVLTQKLIETLKPFGVFEEEEELQR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 RILVLDKLNNLVKEWIREISESKSLPQSVIENVGGKIFTFGSYRLGVHTKGADIDALCVA
:::.: :::::::::::::::::.::::::::::::::::::::::::::::::::::::
XP_005 RILILGKLNNLVKEWIREISESKNLPQSVIENVGGKIFTFGSYRLGVHTKGADIDALCVA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 PSHVDRSDFFTSFYAKLKLQEEVKDLRAVQEAFVPVIKLCFDGIEIDILFARLALQTIPE
: :::::::::::: ::::::::::::::.::::::::::::::::::::::::::::::
XP_005 PRHVDRSDFFTSFYDKLKLQEEVKDLRAVEEAFVPVIKLCFDGIEIDILFARLALQTIPE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 DLDLRDDSLLKNLDIRCIRSLNGCRVTDEILHLVPNIDNFRLTLRAIKLWAKCHNIYSNI
:::::::::::::::::::::::::::::::::::::::::::::::::::: :::::::
XP_005 DLDLRDDSLLKNLDIRCIRSLNGCRVTDEILHLVPNIDNFRLTLRAIKLWAKRHNIYSNI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 LGFLGGVSWAMLVARTCQLYPNAVASTLVRKFFLVFSEWEWPNPVLLKEPEERNLNLPVW
:::::::::::::::::::::::.:::::.:::::::.::::::::::.::: :::::::
XP_005 LGFLGGVSWAMLVARTCQLYPNAIASTLVHKFFLVFSKWEWPNPVLLKQPEECNLNLPVW
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE5 DPRVNPSDRYHLMPIITPAYPQQNSTYNVSISTRMVMIEEFKQGLAITHEILLSKAEWSK
::::::::::::::::::::::::::::::.::::::.:::::::::: :::::::::::
XP_005 DPRVNPSDRYHLMPIITPAYPQQNSTYNVSVSTRMVMVEEFKQGLAITDEILLSKAEWSK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE5 LFEAPSFFQKYKHYIVLLASASTEKQHLEWVGLVESKIRILVGSLEKNEFITLAHVNPQS
:::::.::::::::::::::: ::::.:::::::::::::::::::::::::::::::::
XP_005 LFEAPNFFQKYKHYIVLLASAPTEKQRLEWVGLVESKIRILVGSLEKNEFITLAHVNPQS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE5 FPAPKENPDMEEFRTMWVIGLGLKKPDNSEILSIDLTYDIQSFTDTVYRQAVNSKMFEMG
::::::::: ::::::::::: .:: .::: ::.:::::::::::::::::.::::::.
XP_005 FPAPKENPDKEEFRTMWVIGLVFKKTENSENLSVDLTYDIQSFTDTVYRQAINSKMFEVD
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE5 MKITAVHLRRKELHQLLPHHVLQDKKAHSTEGRRLTDLNDSSFDLSAGCENSMSVPSSTS
:::.:.:..::.::::::.:::: :: ::::: .:: :::::.::: .::::::: ::
XP_005 MKIAAMHVKRKQLHQLLPNHVLQKKKKHSTEGVKLTALNDSSLDLSMDSDNSMSVPSPTS
490 500 510 520 530 540
550 560 570 580 590
pF1KE5 TMKTGPLISS--SQGRNSPALAVMTASVANIQATEFSLQQVNTNESSGVALNESIPHAVS
. ::.:: :: :::::::: :: .:::.:::::: :. :::..:::: . .::::....
XP_005 ATKTSPLNSSGSSQGRNSPAPAVTAASVTNIQATEVSVPQVNSSESSGGTSSESIPQTAT
550 560 570 580 590 600
600 610 620 630
pF1KE5 QPAISPSPKAMVARVVSSTCLISHPDLQETQQQTYLIL
:::::: :: :.:::::: :.. :
XP_005 QPAISPPPKPTVSRVVSSTRLVNPPPRSSGNAATSGNAATKIPTPIVGVKRTSSPHKEES
610 620 630 640 650 660
>>XP_005267338 (OMIM: 605553) PREDICTED: poly(A) polymer (724 aa)
initn: 3525 init1: 3245 opt: 3519 Z-score: 3704.1 bits: 695.8 E(85289): 1.4e-199
Smith-Waterman score: 3519; 85.8% identity (93.6% similar) in 625 aa overlap (1-623:1-625)
10 20 30 40 50 60
pF1KE5 MPFPVTTQGPPQPAPPPNRYGVSSPISLAVPKETDCLLTQRLIETLRPFGVFEEEEELQR
::::::::: : :: ..::..::::::.::::::.:::.:::::.:::::::::::::
XP_005 MPFPVTTQGSQQTQPPQKHYGITSPISLAAPKETDCVLTQKLIETLKPFGVFEEEEELQR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 RILVLDKLNNLVKEWIREISESKSLPQSVIENVGGKIFTFGSYRLGVHTKGADIDALCVA
:::.: :::::::::::::::::.::::::::::::::::::::::::::::::::::::
XP_005 RILILGKLNNLVKEWIREISESKNLPQSVIENVGGKIFTFGSYRLGVHTKGADIDALCVA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 PSHVDRSDFFTSFYAKLKLQEEVKDLRAVQEAFVPVIKLCFDGIEIDILFARLALQTIPE
: :::::::::::: ::::::::::::::.::::::::::::::::::::::::::::::
XP_005 PRHVDRSDFFTSFYDKLKLQEEVKDLRAVEEAFVPVIKLCFDGIEIDILFARLALQTIPE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 DLDLRDDSLLKNLDIRCIRSLNGCRVTDEILHLVPNIDNFRLTLRAIKLWAKCHNIYSNI
:::::::::::::::::::::::::::::::::::::::::::::::::::: :::::::
XP_005 DLDLRDDSLLKNLDIRCIRSLNGCRVTDEILHLVPNIDNFRLTLRAIKLWAKRHNIYSNI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 LGFLGGVSWAMLVARTCQLYPNAVASTLVRKFFLVFSEWEWPNPVLLKEPEERNLNLPVW
:::::::::::::::::::::::.:::::.:::::::.::::::::::.::: :::::::
XP_005 LGFLGGVSWAMLVARTCQLYPNAIASTLVHKFFLVFSKWEWPNPVLLKQPEECNLNLPVW
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE5 DPRVNPSDRYHLMPIITPAYPQQNSTYNVSISTRMVMIEEFKQGLAITHEILLSKAEWSK
::::::::::::::::::::::::::::::.::::::.:::::::::: :::::::::::
XP_005 DPRVNPSDRYHLMPIITPAYPQQNSTYNVSVSTRMVMVEEFKQGLAITDEILLSKAEWSK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE5 LFEAPSFFQKYKHYIVLLASASTEKQHLEWVGLVESKIRILVGSLEKNEFITLAHVNPQS
:::::.::::::::::::::: ::::.:::::::::::::::::::::::::::::::::
XP_005 LFEAPNFFQKYKHYIVLLASAPTEKQRLEWVGLVESKIRILVGSLEKNEFITLAHVNPQS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE5 FPAPKENPDMEEFRTMWVIGLGLKKPDNSEILSIDLTYDIQSFTDTVYRQAVNSKMFEMG
::::::::: ::::::::::: .:: .::: ::.:::::::::::::::::.::::::.
XP_005 FPAPKENPDKEEFRTMWVIGLVFKKTENSENLSVDLTYDIQSFTDTVYRQAINSKMFEVD
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE5 MKITAVHLRRKELHQLLPHHVLQDKKAHSTEGRRLTDLNDSSFDLSAGCENSMSVPSSTS
:::.:.:..::.::::::.:::: :: ::::: .:: :::::.::: .::::::: ::
XP_005 MKIAAMHVKRKQLHQLLPNHVLQKKKKHSTEGVKLTALNDSSLDLSMDSDNSMSVPSPTS
490 500 510 520 530 540
550 560 570 580 590
pF1KE5 TMKTGPLISS--SQGRNSPALAVMTASVANIQATEFSLQQVNTNESSGVALNESIPHAVS
. ::.:: :: :::::::: :: .:::.:::::: :. :::..:::: . .::::....
XP_005 ATKTSPLNSSGSSQGRNSPAPAVTAASVTNIQATEVSVPQVNSSESSGGTSSESIPQTAT
550 560 570 580 590 600
600 610 620 630
pF1KE5 QPAISPSPKAMVARVVSSTCLISHPDLQETQQQTYLIL
:::::: :: :.:::::: :.. :
XP_005 QPAISPPPKPTVSRVVSSTRLVNPPPRSSGNAATSGNAATKIPTPIVGVKRTSSPHKEES
610 620 630 640 650 660
>>NP_116021 (OMIM: 605553) poly(A) polymerase alpha isof (745 aa)
initn: 3525 init1: 3245 opt: 3519 Z-score: 3703.9 bits: 695.8 E(85289): 1.4e-199
Smith-Waterman score: 3519; 85.8% identity (93.6% similar) in 625 aa overlap (1-623:1-625)
10 20 30 40 50 60
pF1KE5 MPFPVTTQGPPQPAPPPNRYGVSSPISLAVPKETDCLLTQRLIETLRPFGVFEEEEELQR
::::::::: : :: ..::..::::::.::::::.:::.:::::.:::::::::::::
NP_116 MPFPVTTQGSQQTQPPQKHYGITSPISLAAPKETDCVLTQKLIETLKPFGVFEEEEELQR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 RILVLDKLNNLVKEWIREISESKSLPQSVIENVGGKIFTFGSYRLGVHTKGADIDALCVA
:::.: :::::::::::::::::.::::::::::::::::::::::::::::::::::::
NP_116 RILILGKLNNLVKEWIREISESKNLPQSVIENVGGKIFTFGSYRLGVHTKGADIDALCVA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 PSHVDRSDFFTSFYAKLKLQEEVKDLRAVQEAFVPVIKLCFDGIEIDILFARLALQTIPE
: :::::::::::: ::::::::::::::.::::::::::::::::::::::::::::::
NP_116 PRHVDRSDFFTSFYDKLKLQEEVKDLRAVEEAFVPVIKLCFDGIEIDILFARLALQTIPE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 DLDLRDDSLLKNLDIRCIRSLNGCRVTDEILHLVPNIDNFRLTLRAIKLWAKCHNIYSNI
:::::::::::::::::::::::::::::::::::::::::::::::::::: :::::::
NP_116 DLDLRDDSLLKNLDIRCIRSLNGCRVTDEILHLVPNIDNFRLTLRAIKLWAKRHNIYSNI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 LGFLGGVSWAMLVARTCQLYPNAVASTLVRKFFLVFSEWEWPNPVLLKEPEERNLNLPVW
:::::::::::::::::::::::.:::::.:::::::.::::::::::.::: :::::::
NP_116 LGFLGGVSWAMLVARTCQLYPNAIASTLVHKFFLVFSKWEWPNPVLLKQPEECNLNLPVW
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE5 DPRVNPSDRYHLMPIITPAYPQQNSTYNVSISTRMVMIEEFKQGLAITHEILLSKAEWSK
::::::::::::::::::::::::::::::.::::::.:::::::::: :::::::::::
NP_116 DPRVNPSDRYHLMPIITPAYPQQNSTYNVSVSTRMVMVEEFKQGLAITDEILLSKAEWSK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE5 LFEAPSFFQKYKHYIVLLASASTEKQHLEWVGLVESKIRILVGSLEKNEFITLAHVNPQS
:::::.::::::::::::::: ::::.:::::::::::::::::::::::::::::::::
NP_116 LFEAPNFFQKYKHYIVLLASAPTEKQRLEWVGLVESKIRILVGSLEKNEFITLAHVNPQS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE5 FPAPKENPDMEEFRTMWVIGLGLKKPDNSEILSIDLTYDIQSFTDTVYRQAVNSKMFEMG
::::::::: ::::::::::: .:: .::: ::.:::::::::::::::::.::::::.
NP_116 FPAPKENPDKEEFRTMWVIGLVFKKTENSENLSVDLTYDIQSFTDTVYRQAINSKMFEVD
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE5 MKITAVHLRRKELHQLLPHHVLQDKKAHSTEGRRLTDLNDSSFDLSAGCENSMSVPSSTS
:::.:.:..::.::::::.:::: :: ::::: .:: :::::.::: .::::::: ::
NP_116 MKIAAMHVKRKQLHQLLPNHVLQKKKKHSTEGVKLTALNDSSLDLSMDSDNSMSVPSPTS
490 500 510 520 530 540
550 560 570 580 590
pF1KE5 TMKTGPLISS--SQGRNSPALAVMTASVANIQATEFSLQQVNTNESSGVALNESIPHAVS
. ::.:: :: :::::::: :: .:::.:::::: :. :::..:::: . .::::....
NP_116 ATKTSPLNSSGSSQGRNSPAPAVTAASVTNIQATEVSVPQVNSSESSGGTSSESIPQTAT
550 560 570 580 590 600
600 610 620 630
pF1KE5 QPAISPSPKAMVARVVSSTCLISHPDLQETQQQTYLIL
:::::: :: :.:::::: :.. :
NP_116 QPAISPPPKPTVSRVVSSTRLVNPPPRSSGNAATSGNAATKIPTPIVGVKRTSSPHKEES
610 620 630 640 650 660
>>XP_016876425 (OMIM: 605553) PREDICTED: poly(A) polymer (698 aa)
initn: 3501 init1: 3253 opt: 3500 Z-score: 3684.4 bits: 692.1 E(85289): 1.8e-198
Smith-Waterman score: 3500; 85.6% identity (93.4% similar) in 625 aa overlap (1-623:1-624)
10 20 30 40 50 60
pF1KE5 MPFPVTTQGPPQPAPPPNRYGVSSPISLAVPKETDCLLTQRLIETLRPFGVFEEEEELQR
::::::::: : :: ..::..::::::.::::::.:::.:::::.:::::::::::::
XP_016 MPFPVTTQGSQQTQPPQKHYGITSPISLAAPKETDCVLTQKLIETLKPFGVFEEEEELQR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 RILVLDKLNNLVKEWIREISESKSLPQSVIENVGGKIFTFGSYRLGVHTKGADIDALCVA
:::.: :::::::::::::::::.::::::::::::::::::::::::::::::::::::
XP_016 RILILGKLNNLVKEWIREISESKNLPQSVIENVGGKIFTFGSYRLGVHTKGADIDALCVA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 PSHVDRSDFFTSFYAKLKLQEEVKDLRAVQEAFVPVIKLCFDGIEIDILFARLALQTIPE
: :::::::::::: ::::::::::::::.::::::::::::::::::::::::::::::
XP_016 PRHVDRSDFFTSFYDKLKLQEEVKDLRAVEEAFVPVIKLCFDGIEIDILFARLALQTIPE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 DLDLRDDSLLKNLDIRCIRSLNGCRVTDEILHLVPNIDNFRLTLRAIKLWAKCHNIYSNI
:::::::::::::::::::::::::::::::::::::::::::::::::::: :::::::
XP_016 DLDLRDDSLLKNLDIRCIRSLNGCRVTDEILHLVPNIDNFRLTLRAIKLWAKRHNIYSNI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 LGFLGGVSWAMLVARTCQLYPNAVASTLVRKFFLVFSEWEWPNPVLLKEPEERNLNLPVW
:::::::::::::::::::::::.:::::.:::::::.::::::::::.::: :::::::
XP_016 LGFLGGVSWAMLVARTCQLYPNAIASTLVHKFFLVFSKWEWPNPVLLKQPEECNLNLPVW
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE5 DPRVNPSDRYHLMPIITPAYPQQNSTYNVSISTRMVMIEEFKQGLAITHEILLSKAEWSK
::::::::::::::::::::::::::::::.::::::.:::::::::: :::::::::::
XP_016 DPRVNPSDRYHLMPIITPAYPQQNSTYNVSVSTRMVMVEEFKQGLAITDEILLSKAEWSK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE5 LFEAPSFFQKYKHYIVLLASASTEKQHLEWVGLVESKIRILVGSLEKNEFITLAHVNPQS
:::::.::::::::::::::: ::::.:::::::::::::::::::::::::::::::::
XP_016 LFEAPNFFQKYKHYIVLLASAPTEKQRLEWVGLVESKIRILVGSLEKNEFITLAHVNPQS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE5 FPAPKENPDMEEFRTMWVIGLGLKKPDNSEILSIDLTYDIQSFTDTVYRQAVNSKMFEMG
::::::::: ::::::::::: .:: .::: ::.:::::::::::::::::.::::::.
XP_016 FPAPKENPDKEEFRTMWVIGLVFKKTENSENLSVDLTYDIQSFTDTVYRQAINSKMFEVD
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE5 MKITAVHLRRKELHQLLPHHVLQDKKAHSTEGRRLTDLNDSSFDLSAGCENSMSVPSSTS
:::.:.:..::.::::::.:::: :: ::::: .:: :::::.::: .::::::: ::
XP_016 MKIAAMHVKRKQLHQLLPNHVLQKKKKHSTEGVKLTALNDSSLDLSMDSDNSMSVPSPTS
490 500 510 520 530 540
550 560 570 580 590
pF1KE5 TMKTGPLISS--SQGRNSPALAVMTASVANIQATEFSLQQVNTNESSGVALNESIPHAVS
. ::.:: :: ::: :::: :: .:::.:::::: :. :::..:::: . .::::....
XP_016 ATKTSPLNSSGSSQG-NSPAPAVTAASVTNIQATEVSVPQVNSSESSGGTSSESIPQTAT
550 560 570 580 590
600 610 620 630
pF1KE5 QPAISPSPKAMVARVVSSTCLISHPDLQETQQQTYLIL
:::::: :: :.:::::: :.. :
XP_016 QPAISPPPKPTVSRVVSSTRLVNPPPRSSGNAATSGNAATKIPTPIVGVKRTSSPHKEES
600 610 620 630 640 650
>>XP_016876424 (OMIM: 605553) PREDICTED: poly(A) polymer (723 aa)
initn: 3501 init1: 3253 opt: 3500 Z-score: 3684.1 bits: 692.1 E(85289): 1.8e-198
Smith-Waterman score: 3500; 85.6% identity (93.4% similar) in 625 aa overlap (1-623:1-624)
10 20 30 40 50 60
pF1KE5 MPFPVTTQGPPQPAPPPNRYGVSSPISLAVPKETDCLLTQRLIETLRPFGVFEEEEELQR
::::::::: : :: ..::..::::::.::::::.:::.:::::.:::::::::::::
XP_016 MPFPVTTQGSQQTQPPQKHYGITSPISLAAPKETDCVLTQKLIETLKPFGVFEEEEELQR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 RILVLDKLNNLVKEWIREISESKSLPQSVIENVGGKIFTFGSYRLGVHTKGADIDALCVA
:::.: :::::::::::::::::.::::::::::::::::::::::::::::::::::::
XP_016 RILILGKLNNLVKEWIREISESKNLPQSVIENVGGKIFTFGSYRLGVHTKGADIDALCVA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 PSHVDRSDFFTSFYAKLKLQEEVKDLRAVQEAFVPVIKLCFDGIEIDILFARLALQTIPE
: :::::::::::: ::::::::::::::.::::::::::::::::::::::::::::::
XP_016 PRHVDRSDFFTSFYDKLKLQEEVKDLRAVEEAFVPVIKLCFDGIEIDILFARLALQTIPE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 DLDLRDDSLLKNLDIRCIRSLNGCRVTDEILHLVPNIDNFRLTLRAIKLWAKCHNIYSNI
:::::::::::::::::::::::::::::::::::::::::::::::::::: :::::::
XP_016 DLDLRDDSLLKNLDIRCIRSLNGCRVTDEILHLVPNIDNFRLTLRAIKLWAKRHNIYSNI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 LGFLGGVSWAMLVARTCQLYPNAVASTLVRKFFLVFSEWEWPNPVLLKEPEERNLNLPVW
:::::::::::::::::::::::.:::::.:::::::.::::::::::.::: :::::::
XP_016 LGFLGGVSWAMLVARTCQLYPNAIASTLVHKFFLVFSKWEWPNPVLLKQPEECNLNLPVW
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE5 DPRVNPSDRYHLMPIITPAYPQQNSTYNVSISTRMVMIEEFKQGLAITHEILLSKAEWSK
::::::::::::::::::::::::::::::.::::::.:::::::::: :::::::::::
XP_016 DPRVNPSDRYHLMPIITPAYPQQNSTYNVSVSTRMVMVEEFKQGLAITDEILLSKAEWSK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE5 LFEAPSFFQKYKHYIVLLASASTEKQHLEWVGLVESKIRILVGSLEKNEFITLAHVNPQS
:::::.::::::::::::::: ::::.:::::::::::::::::::::::::::::::::
XP_016 LFEAPNFFQKYKHYIVLLASAPTEKQRLEWVGLVESKIRILVGSLEKNEFITLAHVNPQS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE5 FPAPKENPDMEEFRTMWVIGLGLKKPDNSEILSIDLTYDIQSFTDTVYRQAVNSKMFEMG
::::::::: ::::::::::: .:: .::: ::.:::::::::::::::::.::::::.
XP_016 FPAPKENPDKEEFRTMWVIGLVFKKTENSENLSVDLTYDIQSFTDTVYRQAINSKMFEVD
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE5 MKITAVHLRRKELHQLLPHHVLQDKKAHSTEGRRLTDLNDSSFDLSAGCENSMSVPSSTS
:::.:.:..::.::::::.:::: :: ::::: .:: :::::.::: .::::::: ::
XP_016 MKIAAMHVKRKQLHQLLPNHVLQKKKKHSTEGVKLTALNDSSLDLSMDSDNSMSVPSPTS
490 500 510 520 530 540
550 560 570 580 590
pF1KE5 TMKTGPLISS--SQGRNSPALAVMTASVANIQATEFSLQQVNTNESSGVALNESIPHAVS
. ::.:: :: ::: :::: :: .:::.:::::: :. :::..:::: . .::::....
XP_016 ATKTSPLNSSGSSQG-NSPAPAVTAASVTNIQATEVSVPQVNSSESSGGTSSESIPQTAT
550 560 570 580 590
600 610 620 630
pF1KE5 QPAISPSPKAMVARVVSSTCLISHPDLQETQQQTYLIL
:::::: :: :.:::::: :.. :
XP_016 QPAISPPPKPTVSRVVSSTRLVNPPPRSSGNAATSGNAATKIPTPIVGVKRTSSPHKEES
600 610 620 630 640 650
>>NP_001280556 (OMIM: 605553) poly(A) polymerase alpha i (744 aa)
initn: 3501 init1: 3253 opt: 3500 Z-score: 3683.9 bits: 692.1 E(85289): 1.9e-198
Smith-Waterman score: 3500; 85.6% identity (93.4% similar) in 625 aa overlap (1-623:1-624)
10 20 30 40 50 60
pF1KE5 MPFPVTTQGPPQPAPPPNRYGVSSPISLAVPKETDCLLTQRLIETLRPFGVFEEEEELQR
::::::::: : :: ..::..::::::.::::::.:::.:::::.:::::::::::::
NP_001 MPFPVTTQGSQQTQPPQKHYGITSPISLAAPKETDCVLTQKLIETLKPFGVFEEEEELQR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 RILVLDKLNNLVKEWIREISESKSLPQSVIENVGGKIFTFGSYRLGVHTKGADIDALCVA
:::.: :::::::::::::::::.::::::::::::::::::::::::::::::::::::
NP_001 RILILGKLNNLVKEWIREISESKNLPQSVIENVGGKIFTFGSYRLGVHTKGADIDALCVA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 PSHVDRSDFFTSFYAKLKLQEEVKDLRAVQEAFVPVIKLCFDGIEIDILFARLALQTIPE
: :::::::::::: ::::::::::::::.::::::::::::::::::::::::::::::
NP_001 PRHVDRSDFFTSFYDKLKLQEEVKDLRAVEEAFVPVIKLCFDGIEIDILFARLALQTIPE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 DLDLRDDSLLKNLDIRCIRSLNGCRVTDEILHLVPNIDNFRLTLRAIKLWAKCHNIYSNI
:::::::::::::::::::::::::::::::::::::::::::::::::::: :::::::
NP_001 DLDLRDDSLLKNLDIRCIRSLNGCRVTDEILHLVPNIDNFRLTLRAIKLWAKRHNIYSNI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 LGFLGGVSWAMLVARTCQLYPNAVASTLVRKFFLVFSEWEWPNPVLLKEPEERNLNLPVW
:::::::::::::::::::::::.:::::.:::::::.::::::::::.::: :::::::
NP_001 LGFLGGVSWAMLVARTCQLYPNAIASTLVHKFFLVFSKWEWPNPVLLKQPEECNLNLPVW
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE5 DPRVNPSDRYHLMPIITPAYPQQNSTYNVSISTRMVMIEEFKQGLAITHEILLSKAEWSK
::::::::::::::::::::::::::::::.::::::.:::::::::: :::::::::::
NP_001 DPRVNPSDRYHLMPIITPAYPQQNSTYNVSVSTRMVMVEEFKQGLAITDEILLSKAEWSK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE5 LFEAPSFFQKYKHYIVLLASASTEKQHLEWVGLVESKIRILVGSLEKNEFITLAHVNPQS
:::::.::::::::::::::: ::::.:::::::::::::::::::::::::::::::::
NP_001 LFEAPNFFQKYKHYIVLLASAPTEKQRLEWVGLVESKIRILVGSLEKNEFITLAHVNPQS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE5 FPAPKENPDMEEFRTMWVIGLGLKKPDNSEILSIDLTYDIQSFTDTVYRQAVNSKMFEMG
::::::::: ::::::::::: .:: .::: ::.:::::::::::::::::.::::::.
NP_001 FPAPKENPDKEEFRTMWVIGLVFKKTENSENLSVDLTYDIQSFTDTVYRQAINSKMFEVD
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE5 MKITAVHLRRKELHQLLPHHVLQDKKAHSTEGRRLTDLNDSSFDLSAGCENSMSVPSSTS
:::.:.:..::.::::::.:::: :: ::::: .:: :::::.::: .::::::: ::
NP_001 MKIAAMHVKRKQLHQLLPNHVLQKKKKHSTEGVKLTALNDSSLDLSMDSDNSMSVPSPTS
490 500 510 520 530 540
550 560 570 580 590
pF1KE5 TMKTGPLISS--SQGRNSPALAVMTASVANIQATEFSLQQVNTNESSGVALNESIPHAVS
. ::.:: :: ::: :::: :: .:::.:::::: :. :::..:::: . .::::....
NP_001 ATKTSPLNSSGSSQG-NSPAPAVTAASVTNIQATEVSVPQVNSSESSGGTSSESIPQTAT
550 560 570 580 590
600 610 620 630
pF1KE5 QPAISPSPKAMVARVVSSTCLISHPDLQETQQQTYLIL
:::::: :: :.:::::: :.. :
NP_001 QPAISPPPKPTVSRVVSSTRLVNPPPRSSGNAATSGNAATKIPTPIVGVKRTSSPHKEES
600 610 620 630 640 650
>>XP_005264557 (OMIM: 616865) PREDICTED: poly(A) polymer (714 aa)
initn: 2502 init1: 2502 opt: 2539 Z-score: 2672.2 bits: 504.8 E(85289): 4.2e-142
Smith-Waterman score: 2539; 63.6% identity (83.1% similar) in 615 aa overlap (20-626:19-626)
10 20 30 40 50 60
pF1KE5 MPFPVTTQGPPQPAPPPNRYGVSSPISLAVPKETDCLLTQRLIETLRPFGVFEEEEELQR
::..:::::: ::: : . ::.::....::::::.::::..
XP_005 MKEMSANTVLDSQRQQKHYGITSPISLASPKEIDHIYTQKLIDAMKPFGVFEDEEELNH
10 20 30 40 50
70 80 90 100 110 120
pF1KE5 RILVLDKLNNLVKEWIREISESKSLPQSVIENVGGKIFTFGSYRLGVHTKGADIDALCVA
:..:: :::::::::: ..::::.:: ::. .::::::::::::::::::::::::::::
XP_005 RLVVLGKLNNLVKEWISDVSESKNLPPSVVATVGGKIFTFGSYRLGVHTKGADIDALCVA
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE5 PSHVDRSDFFTSFYAKLKLQEEVKDLRAVQEAFVPVIKLCFDGIEIDILFARLALQTIPE
: ::.::::: ::. ::: :. ...::::..:::::::. :::::::..:::::.::: .
XP_005 PRHVERSDFFQSFFEKLKHQDGIRNLRAVEDAFVPVIKFEFDGIEIDLVFARLAIQTISD
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE5 DLDLRDDSLLKNLDIRCIRSLNGCRVTDEILHLVPNIDNFRLTLRAIKLWAKCHNIYSNI
.::::::: :..:::::::::::::::::::::::: ..:::::::.::::: ..::::.
XP_005 NLDLRDDSRLRSLDIRCIRSLNGCRVTDEILHLVPNKETFRLTLRAVKLWAKRRGIYSNM
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE5 LGFLGGVSWAMLVARTCQLYPNAVASTLVRKFFLVFSEWEWPNPVLLKEPEERNLNLPVW
:::::::::::::::::::::::.:::::.:::::::.::::::::::.::: :::::::
XP_005 LGFLGGVSWAMLVARTCQLYPNAAASTLVHKFFLVFSKWEWPNPVLLKQPEESNLNLPVW
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE5 DPRVNPSDRYHLMPIITPAYPQQNSTYNVSISTRMVMIEEFKQGLAITHEILLSKAEWSK
:::::::::::::::::::::::::::::: ::: ::.::::::::.: ::: .:..:::
XP_005 DPRVNPSDRYHLMPIITPAYPQQNSTYNVSTSTRTVMVEEFKQGLAVTDEILQGKSDWSK
300 310 320 330 340 350
370 380 390 400 410 420
pF1KE5 LFEAPSFFQKYKHYIVLLASASTEKQHLEWVGLVESKIRILVGSLEKNEFITLAHVNPQS
:.: :.:::::.::::: ::::::..:::::::::::::.:::.::.:::::::::::::
XP_005 LLEPPNFFQKYRHYIVLTASASTEENHLEWVGLVESKIRVLVGNLERNEFITLAHVNPQS
360 370 380 390 400 410
430 440 450 460 470 480
pF1KE5 FPAPKENPDMEEFRTMWVIGLGLKKPDNSEILSIDLTYDIQSFTDTVYRQAVNSKMFEMG
::. ::. ... .:: .:. ... .:.: ..:::::::::::::::::: : .:.. :
XP_005 FPGNKEHHKDNNYVSMWFLGIIFRRVENAESVNIDLTYDIQSFTDTVYRQANNINMLKEG
420 430 440 450 460 470
490 500 510 520 530
pF1KE5 MKITAVHLRRKELHQLLPHHVLQDKKAHSTEGRRLTDLNDSSFDLSAG--CENSMSVPSS
::: :.:...:.::. :: ..:: :: .: :.:.: :: :.. .: . ::
XP_005 MKIEATHVKKKQLHHYLPAEILQKKKKQS-----LSDVNRSSGGLQSKRLSLDSSCLDSS
480 490 500 510 520 530
540 550 560 570 580 590
pF1KE5 TSTMKTGPLISSSQGRNSPALAVMTASVANIQATEFSLQQVNTNESSGVALN------ES
.: . :. : .. .::... . :. :. . . ... ..:... .:
XP_005 RDTDNGTPFNSPASKSDSPSVGETERNSAE-PAAVIVEKPLSVPPAQGLSIPVIGAKVDS
540 550 560 570 580 590
600 610 620 630
pF1KE5 IPHAVSQPAISPSPKAMVARVVSSTCLISHPDLQETQQQTYLIL
..:: :.. : ..:.: : : :
XP_005 TVKTVSPPTVCTIP-TVVGRNVIPRITTPHNPAQGQPHLNGMSNITKTVTPKRSHSPSID
600 610 620 630 640 650
XP_005 GTPKRLKDVEKDAIGGESMPIPTIDTSRKKRLPSKELPDSSSPVPANNIRVIKNSIRLTL
660 670 680 690 700 710
>>NP_075045 (OMIM: 616865) poly(A) polymerase gamma [Hom (736 aa)
initn: 2502 init1: 2502 opt: 2539 Z-score: 2672.0 bits: 504.8 E(85289): 4.3e-142
Smith-Waterman score: 2539; 63.6% identity (83.1% similar) in 615 aa overlap (20-626:19-626)
10 20 30 40 50 60
pF1KE5 MPFPVTTQGPPQPAPPPNRYGVSSPISLAVPKETDCLLTQRLIETLRPFGVFEEEEELQR
::..:::::: ::: : . ::.::....::::::.::::..
NP_075 MKEMSANTVLDSQRQQKHYGITSPISLASPKEIDHIYTQKLIDAMKPFGVFEDEEELNH
10 20 30 40 50
70 80 90 100 110 120
pF1KE5 RILVLDKLNNLVKEWIREISESKSLPQSVIENVGGKIFTFGSYRLGVHTKGADIDALCVA
:..:: :::::::::: ..::::.:: ::. .::::::::::::::::::::::::::::
NP_075 RLVVLGKLNNLVKEWISDVSESKNLPPSVVATVGGKIFTFGSYRLGVHTKGADIDALCVA
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE5 PSHVDRSDFFTSFYAKLKLQEEVKDLRAVQEAFVPVIKLCFDGIEIDILFARLALQTIPE
: ::.::::: ::. ::: :. ...::::..:::::::. :::::::..:::::.::: .
NP_075 PRHVERSDFFQSFFEKLKHQDGIRNLRAVEDAFVPVIKFEFDGIEIDLVFARLAIQTISD
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE5 DLDLRDDSLLKNLDIRCIRSLNGCRVTDEILHLVPNIDNFRLTLRAIKLWAKCHNIYSNI
.::::::: :..:::::::::::::::::::::::: ..:::::::.::::: ..::::.
NP_075 NLDLRDDSRLRSLDIRCIRSLNGCRVTDEILHLVPNKETFRLTLRAVKLWAKRRGIYSNM
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE5 LGFLGGVSWAMLVARTCQLYPNAVASTLVRKFFLVFSEWEWPNPVLLKEPEERNLNLPVW
:::::::::::::::::::::::.:::::.:::::::.::::::::::.::: :::::::
NP_075 LGFLGGVSWAMLVARTCQLYPNAAASTLVHKFFLVFSKWEWPNPVLLKQPEESNLNLPVW
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE5 DPRVNPSDRYHLMPIITPAYPQQNSTYNVSISTRMVMIEEFKQGLAITHEILLSKAEWSK
:::::::::::::::::::::::::::::: ::: ::.::::::::.: ::: .:..:::
NP_075 DPRVNPSDRYHLMPIITPAYPQQNSTYNVSTSTRTVMVEEFKQGLAVTDEILQGKSDWSK
300 310 320 330 340 350
370 380 390 400 410 420
pF1KE5 LFEAPSFFQKYKHYIVLLASASTEKQHLEWVGLVESKIRILVGSLEKNEFITLAHVNPQS
:.: :.:::::.::::: ::::::..:::::::::::::.:::.::.:::::::::::::
NP_075 LLEPPNFFQKYRHYIVLTASASTEENHLEWVGLVESKIRVLVGNLERNEFITLAHVNPQS
360 370 380 390 400 410
430 440 450 460 470 480
pF1KE5 FPAPKENPDMEEFRTMWVIGLGLKKPDNSEILSIDLTYDIQSFTDTVYRQAVNSKMFEMG
::. ::. ... .:: .:. ... .:.: ..:::::::::::::::::: : .:.. :
NP_075 FPGNKEHHKDNNYVSMWFLGIIFRRVENAESVNIDLTYDIQSFTDTVYRQANNINMLKEG
420 430 440 450 460 470
490 500 510 520 530
pF1KE5 MKITAVHLRRKELHQLLPHHVLQDKKAHSTEGRRLTDLNDSSFDLSAG--CENSMSVPSS
::: :.:...:.::. :: ..:: :: .: :.:.: :: :.. .: . ::
NP_075 MKIEATHVKKKQLHHYLPAEILQKKKKQS-----LSDVNRSSGGLQSKRLSLDSSCLDSS
480 490 500 510 520 530
540 550 560 570 580 590
pF1KE5 TSTMKTGPLISSSQGRNSPALAVMTASVANIQATEFSLQQVNTNESSGVALN------ES
.: . :. : .. .::... . :. :. . . ... ..:... .:
NP_075 RDTDNGTPFNSPASKSDSPSVGETERNSAE-PAAVIVEKPLSVPPAQGLSIPVIGAKVDS
540 550 560 570 580 590
600 610 620 630
pF1KE5 IPHAVSQPAISPSPKAMVARVVSSTCLISHPDLQETQQQTYLIL
..:: :.. : ..:.: : : :
NP_075 TVKTVSPPTVCTIP-TVVGRNVIPRITTPHNPAQGQPHLNGMSNITKTVTPKRSHSPSID
600 610 620 630 640 650
NP_075 GTPKRLKDVEKFIRLESTFKDPRTAEERKRKSVDAIGGESMPIPTIDTSRKKRLPSKELP
660 670 680 690 700 710
>>XP_005264558 (OMIM: 616865) PREDICTED: poly(A) polymer (692 aa)
initn: 2393 init1: 2393 opt: 2430 Z-score: 2557.7 bits: 483.6 E(85289): 1e-135
Smith-Waterman score: 2430; 63.7% identity (83.0% similar) in 589 aa overlap (46-626:1-582)
20 30 40 50 60 70
pF1KE5 PPNRYGVSSPISLAVPKETDCLLTQRLIETLRPFGVFEEEEELQRRILVLDKLNNLVKEW
..::::::.::::..:..:: :::::::::
XP_005 MKPFGVFEDEEELNHRLVVLGKLNNLVKEW
10 20 30
80 90 100 110 120 130
pF1KE5 IREISESKSLPQSVIENVGGKIFTFGSYRLGVHTKGADIDALCVAPSHVDRSDFFTSFYA
: ..::::.:: ::. .::::::::::::::::::::::::::::: ::.::::: ::.
XP_005 ISDVSESKNLPPSVVATVGGKIFTFGSYRLGVHTKGADIDALCVAPRHVERSDFFQSFFE
40 50 60 70 80 90
140 150 160 170 180 190
pF1KE5 KLKLQEEVKDLRAVQEAFVPVIKLCFDGIEIDILFARLALQTIPEDLDLRDDSLLKNLDI
::: :. ...::::..:::::::. :::::::..:::::.::: ..::::::: :..:::
XP_005 KLKHQDGIRNLRAVEDAFVPVIKFEFDGIEIDLVFARLAIQTISDNLDLRDDSRLRSLDI
100 110 120 130 140 150
200 210 220 230 240 250
pF1KE5 RCIRSLNGCRVTDEILHLVPNIDNFRLTLRAIKLWAKCHNIYSNILGFLGGVSWAMLVAR
::::::::::::::::::::: ..:::::::.::::: ..::::.:::::::::::::::
XP_005 RCIRSLNGCRVTDEILHLVPNKETFRLTLRAVKLWAKRRGIYSNMLGFLGGVSWAMLVAR
160 170 180 190 200 210
260 270 280 290 300 310
pF1KE5 TCQLYPNAVASTLVRKFFLVFSEWEWPNPVLLKEPEERNLNLPVWDPRVNPSDRYHLMPI
::::::::.:::::.:::::::.::::::::::.::: ::::::::::::::::::::::
XP_005 TCQLYPNAAASTLVHKFFLVFSKWEWPNPVLLKQPEESNLNLPVWDPRVNPSDRYHLMPI
220 230 240 250 260 270
320 330 340 350 360 370
pF1KE5 ITPAYPQQNSTYNVSISTRMVMIEEFKQGLAITHEILLSKAEWSKLFEAPSFFQKYKHYI
::::::::::::::: ::: ::.::::::::.: ::: .:..::::.: :.:::::.:::
XP_005 ITPAYPQQNSTYNVSTSTRTVMVEEFKQGLAVTDEILQGKSDWSKLLEPPNFFQKYRHYI
280 290 300 310 320 330
380 390 400 410 420 430
pF1KE5 VLLASASTEKQHLEWVGLVESKIRILVGSLEKNEFITLAHVNPQSFPAPKENPDMEEFRT
:: ::::::..:::::::::::::.:::.::.:::::::::::::::. ::. ... .
XP_005 VLTASASTEENHLEWVGLVESKIRVLVGNLERNEFITLAHVNPQSFPGNKEHHKDNNYVS
340 350 360 370 380 390
440 450 460 470 480 490
pF1KE5 MWVIGLGLKKPDNSEILSIDLTYDIQSFTDTVYRQAVNSKMFEMGMKITAVHLRRKELHQ
:: .:. ... .:.: ..:::::::::::::::::: : .:.. :::: :.:...:.::.
XP_005 MWFLGIIFRRVENAESVNIDLTYDIQSFTDTVYRQANNINMLKEGMKIEATHVKKKQLHH
400 410 420 430 440 450
500 510 520 530 540 550
pF1KE5 LLPHHVLQDKKAHSTEGRRLTDLNDSSFDLSAG--CENSMSVPSSTSTMKTGPLISSSQG
:: ..:: :: .: :.:.: :: :.. .: . :: .: . :. : ..
XP_005 YLPAEILQKKKKQS-----LSDVNRSSGGLQSKRLSLDSSCLDSSRDTDNGTPFNSPASK
460 470 480 490 500
560 570 580 590 600
pF1KE5 RNSPALAVMTASVANIQATEFSLQQVNTNESSGVALN------ESIPHAVSQPAISPSPK
.::... . :. :. . . ... ..:... .: ..:: :.. :
XP_005 SDSPSVGETERNSAE-PAAVIVEKPLSVPPAQGLSIPVIGAKVDSTVKTVSPPTVCTIP-
510 520 530 540 550 560
610 620 630
pF1KE5 AMVARVVSSTCLISHPDLQETQQQTYLIL
..:.: : : :
XP_005 TVVGRNVIPRITTPHNPAQGQPHLNGMSNITKTVTPKRSHSPSIDGTPKRLKDVEKFIRL
570 580 590 600 610 620
636 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 04:02:51 2016 done: Tue Nov 8 04:02:52 2016
Total Scan time: 9.790 Total Display time: 0.130
Function used was FASTA [36.3.4 Apr, 2011]