Result of FASTA (omim) for
pFN21AE4580
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE4580, 800 aa
1>>>pF1KE4580 800 - 800 aa - 800 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.2667+/-0.000394; mu= 9.0283+/- 0.025
mean_var=231.4928+/-47.184, 0's: 0 Z-trim(119.7): 14 B-trim: 710 in 2/55
Lambda= 0.084296
statistics sampled from 34054 (34072) to 34054 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.724), E-opt: 0.2 (0.399), width: 16
Scan time: 15.500
The best scores are: opt bits E(85289)
NP_005137 (OMIM: 605941) U4/U6.U5 tri-snRNP-associ ( 800) 5161 641.3 5e-183
XP_011543646 (OMIM: 605941) PREDICTED: U4/U6.U5 tr ( 702) 4463 556.3 1.6e-157
XP_011543647 (OMIM: 605941) PREDICTED: U4/U6.U5 tr ( 642) 4142 517.3 8.6e-146
>>NP_005137 (OMIM: 605941) U4/U6.U5 tri-snRNP-associated (800 aa)
initn: 5161 init1: 5161 opt: 5161 Z-score: 3407.0 bits: 641.3 E(85289): 5e-183
Smith-Waterman score: 5161; 100.0% identity (100.0% similar) in 800 aa overlap (1-800:1-800)
10 20 30 40 50 60
pF1KE4 MGSSKKHRGEKEAAGTTAAAGTGGATEQPPRHREHKKHKHRSGGSGGSGGERRKRSRERG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MGSSKKHRGEKEAAGTTAAAGTGGATEQPPRHREHKKHKHRSGGSGGSGGERRKRSRERG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 GERGSGRRGAEAEARSSTHGRERSQAEPSERRVKREKRDDGYEAAASSKTSSGDASSLSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 GERGSGRRGAEAEARSSTHGRERSQAEPSERRVKREKRDDGYEAAASSKTSSGDASSLSI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 EETNKLRAKLGLKPLEVNAIKKEAGTKEEPVTADVINPMALRQREELREKLAAAKEKRLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 EETNKLRAKLGLKPLEVNAIKKEAGTKEEPVTADVINPMALRQREELREKLAAAKEKRLL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 NQKLGKIKTLGEDDPWLDDTAAWIERSRQLQKEKDLAEKRAKLLEEMDQEFGVSTLVEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 NQKLGKIKTLGEDDPWLDDTAAWIERSRQLQKEKDLAEKRAKLLEEMDQEFGVSTLVEEE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 FGQRRQDLYSARDLQGLTVEHAIDSFREGETMILTLKDKGVLQEEEDVLVNVNLVDKERA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 FGQRRQDLYSARDLQGLTVEHAIDSFREGETMILTLKDKGVLQEEEDVLVNVNLVDKERA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 EKNVELRKKKPDYLPYAEDESVDDLAQQKPRSILSKYDEELEGERPHSFRLEQGGTADGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 EKNVELRKKKPDYLPYAEDESVDDLAQQKPRSILSKYDEELEGERPHSFRLEQGGTADGL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 RERELEEIRAKLRLQAQSLSTVGPRLASEYLTPEEMVTFKKTKRRVKKIRKKEKEVVVRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 RERELEEIRAKLRLQAQSLSTVGPRLASEYLTPEEMVTFKKTKRRVKKIRKKEKEVVVRA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE4 DDLLPLGDQTQDGDFGSRLRGRGRRRVSEVEEEKEPVPQPLPSDDTRVENMDISDEEEGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 DDLLPLGDQTQDGDFGSRLRGRGRRRVSEVEEEKEPVPQPLPSDDTRVENMDISDEEEGG
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE4 APPPGSPQVLEEDEAELELQKQLEKGRRLRQLQQLQQLRDSGEKVVEIVKKLESRQRGWE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 APPPGSPQVLEEDEAELELQKQLEKGRRLRQLQQLQQLRDSGEKVVEIVKKLESRQRGWE
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE4 EDEDPERKGAIVFNATSEFCRTLGEIPTYGLAGNREEQEELMDFERDEERSANGGSESDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 EDEDPERKGAIVFNATSEFCRTLGEIPTYGLAGNREEQEELMDFERDEERSANGGSESDG
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE4 EENIGWSTVNLDEEKQQQDFSASSTTILDEEPIVNRGLAAALLLCQNKGLLETTVQKVAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 EENIGWSTVNLDEEKQQQDFSASSTTILDEEPIVNRGLAAALLLCQNKGLLETTVQKVAR
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE4 VKAPNKSLPSAVYCIEDKMAIDDKYSRREEYRGFTQDFKEKDGYKPDVKIEYVDETGRKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 VKAPNKSLPSAVYCIEDKMAIDDKYSRREEYRGFTQDFKEKDGYKPDVKIEYVDETGRKL
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE4 TPKEAFRQLSHRFHGKGSGKMKTERRMKKLDEEALLKKMSSSDTPLGTVALLQEKQKAQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 TPKEAFRQLSHRFHGKGSGKMKTERRMKKLDEEALLKKMSSSDTPLGTVALLQEKQKAQK
730 740 750 760 770 780
790 800
pF1KE4 TPYIVLSGSGKSMNANTITK
::::::::::::::::::::
NP_005 TPYIVLSGSGKSMNANTITK
790 800
>>XP_011543646 (OMIM: 605941) PREDICTED: U4/U6.U5 tri-sn (702 aa)
initn: 4463 init1: 4463 opt: 4463 Z-score: 2948.9 bits: 556.3 E(85289): 1.6e-157
Smith-Waterman score: 4463; 100.0% identity (100.0% similar) in 696 aa overlap (105-800:7-702)
80 90 100 110 120 130
pF1KE4 RSSTHGRERSQAEPSERRVKREKRDDGYEAAASSKTSSGDASSLSIEETNKLRAKLGLKP
::::::::::::::::::::::::::::::
XP_011 MLLLVPAASSKTSSGDASSLSIEETNKLRAKLGLKP
10 20 30
140 150 160 170 180 190
pF1KE4 LEVNAIKKEAGTKEEPVTADVINPMALRQREELREKLAAAKEKRLLNQKLGKIKTLGEDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LEVNAIKKEAGTKEEPVTADVINPMALRQREELREKLAAAKEKRLLNQKLGKIKTLGEDD
40 50 60 70 80 90
200 210 220 230 240 250
pF1KE4 PWLDDTAAWIERSRQLQKEKDLAEKRAKLLEEMDQEFGVSTLVEEEFGQRRQDLYSARDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PWLDDTAAWIERSRQLQKEKDLAEKRAKLLEEMDQEFGVSTLVEEEFGQRRQDLYSARDL
100 110 120 130 140 150
260 270 280 290 300 310
pF1KE4 QGLTVEHAIDSFREGETMILTLKDKGVLQEEEDVLVNVNLVDKERAEKNVELRKKKPDYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QGLTVEHAIDSFREGETMILTLKDKGVLQEEEDVLVNVNLVDKERAEKNVELRKKKPDYL
160 170 180 190 200 210
320 330 340 350 360 370
pF1KE4 PYAEDESVDDLAQQKPRSILSKYDEELEGERPHSFRLEQGGTADGLRERELEEIRAKLRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PYAEDESVDDLAQQKPRSILSKYDEELEGERPHSFRLEQGGTADGLRERELEEIRAKLRL
220 230 240 250 260 270
380 390 400 410 420 430
pF1KE4 QAQSLSTVGPRLASEYLTPEEMVTFKKTKRRVKKIRKKEKEVVVRADDLLPLGDQTQDGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QAQSLSTVGPRLASEYLTPEEMVTFKKTKRRVKKIRKKEKEVVVRADDLLPLGDQTQDGD
280 290 300 310 320 330
440 450 460 470 480 490
pF1KE4 FGSRLRGRGRRRVSEVEEEKEPVPQPLPSDDTRVENMDISDEEEGGAPPPGSPQVLEEDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FGSRLRGRGRRRVSEVEEEKEPVPQPLPSDDTRVENMDISDEEEGGAPPPGSPQVLEEDE
340 350 360 370 380 390
500 510 520 530 540 550
pF1KE4 AELELQKQLEKGRRLRQLQQLQQLRDSGEKVVEIVKKLESRQRGWEEDEDPERKGAIVFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AELELQKQLEKGRRLRQLQQLQQLRDSGEKVVEIVKKLESRQRGWEEDEDPERKGAIVFN
400 410 420 430 440 450
560 570 580 590 600 610
pF1KE4 ATSEFCRTLGEIPTYGLAGNREEQEELMDFERDEERSANGGSESDGEENIGWSTVNLDEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ATSEFCRTLGEIPTYGLAGNREEQEELMDFERDEERSANGGSESDGEENIGWSTVNLDEE
460 470 480 490 500 510
620 630 640 650 660 670
pF1KE4 KQQQDFSASSTTILDEEPIVNRGLAAALLLCQNKGLLETTVQKVARVKAPNKSLPSAVYC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KQQQDFSASSTTILDEEPIVNRGLAAALLLCQNKGLLETTVQKVARVKAPNKSLPSAVYC
520 530 540 550 560 570
680 690 700 710 720 730
pF1KE4 IEDKMAIDDKYSRREEYRGFTQDFKEKDGYKPDVKIEYVDETGRKLTPKEAFRQLSHRFH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IEDKMAIDDKYSRREEYRGFTQDFKEKDGYKPDVKIEYVDETGRKLTPKEAFRQLSHRFH
580 590 600 610 620 630
740 750 760 770 780 790
pF1KE4 GKGSGKMKTERRMKKLDEEALLKKMSSSDTPLGTVALLQEKQKAQKTPYIVLSGSGKSMN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GKGSGKMKTERRMKKLDEEALLKKMSSSDTPLGTVALLQEKQKAQKTPYIVLSGSGKSMN
640 650 660 670 680 690
800
pF1KE4 ANTITK
::::::
XP_011 ANTITK
700
>>XP_011543647 (OMIM: 605941) PREDICTED: U4/U6.U5 tri-sn (642 aa)
initn: 4142 init1: 4142 opt: 4142 Z-score: 2738.4 bits: 517.3 E(85289): 8.6e-146
Smith-Waterman score: 4142; 100.0% identity (100.0% similar) in 642 aa overlap (159-800:1-642)
130 140 150 160 170 180
pF1KE4 KLGLKPLEVNAIKKEAGTKEEPVTADVINPMALRQREELREKLAAAKEKRLLNQKLGKIK
::::::::::::::::::::::::::::::
XP_011 MALRQREELREKLAAAKEKRLLNQKLGKIK
10 20 30
190 200 210 220 230 240
pF1KE4 TLGEDDPWLDDTAAWIERSRQLQKEKDLAEKRAKLLEEMDQEFGVSTLVEEEFGQRRQDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TLGEDDPWLDDTAAWIERSRQLQKEKDLAEKRAKLLEEMDQEFGVSTLVEEEFGQRRQDL
40 50 60 70 80 90
250 260 270 280 290 300
pF1KE4 YSARDLQGLTVEHAIDSFREGETMILTLKDKGVLQEEEDVLVNVNLVDKERAEKNVELRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YSARDLQGLTVEHAIDSFREGETMILTLKDKGVLQEEEDVLVNVNLVDKERAEKNVELRK
100 110 120 130 140 150
310 320 330 340 350 360
pF1KE4 KKPDYLPYAEDESVDDLAQQKPRSILSKYDEELEGERPHSFRLEQGGTADGLRERELEEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KKPDYLPYAEDESVDDLAQQKPRSILSKYDEELEGERPHSFRLEQGGTADGLRERELEEI
160 170 180 190 200 210
370 380 390 400 410 420
pF1KE4 RAKLRLQAQSLSTVGPRLASEYLTPEEMVTFKKTKRRVKKIRKKEKEVVVRADDLLPLGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RAKLRLQAQSLSTVGPRLASEYLTPEEMVTFKKTKRRVKKIRKKEKEVVVRADDLLPLGD
220 230 240 250 260 270
430 440 450 460 470 480
pF1KE4 QTQDGDFGSRLRGRGRRRVSEVEEEKEPVPQPLPSDDTRVENMDISDEEEGGAPPPGSPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QTQDGDFGSRLRGRGRRRVSEVEEEKEPVPQPLPSDDTRVENMDISDEEEGGAPPPGSPQ
280 290 300 310 320 330
490 500 510 520 530 540
pF1KE4 VLEEDEAELELQKQLEKGRRLRQLQQLQQLRDSGEKVVEIVKKLESRQRGWEEDEDPERK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VLEEDEAELELQKQLEKGRRLRQLQQLQQLRDSGEKVVEIVKKLESRQRGWEEDEDPERK
340 350 360 370 380 390
550 560 570 580 590 600
pF1KE4 GAIVFNATSEFCRTLGEIPTYGLAGNREEQEELMDFERDEERSANGGSESDGEENIGWST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GAIVFNATSEFCRTLGEIPTYGLAGNREEQEELMDFERDEERSANGGSESDGEENIGWST
400 410 420 430 440 450
610 620 630 640 650 660
pF1KE4 VNLDEEKQQQDFSASSTTILDEEPIVNRGLAAALLLCQNKGLLETTVQKVARVKAPNKSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VNLDEEKQQQDFSASSTTILDEEPIVNRGLAAALLLCQNKGLLETTVQKVARVKAPNKSL
460 470 480 490 500 510
670 680 690 700 710 720
pF1KE4 PSAVYCIEDKMAIDDKYSRREEYRGFTQDFKEKDGYKPDVKIEYVDETGRKLTPKEAFRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PSAVYCIEDKMAIDDKYSRREEYRGFTQDFKEKDGYKPDVKIEYVDETGRKLTPKEAFRQ
520 530 540 550 560 570
730 740 750 760 770 780
pF1KE4 LSHRFHGKGSGKMKTERRMKKLDEEALLKKMSSSDTPLGTVALLQEKQKAQKTPYIVLSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSHRFHGKGSGKMKTERRMKKLDEEALLKKMSSSDTPLGTVALLQEKQKAQKTPYIVLSG
580 590 600 610 620 630
790 800
pF1KE4 SGKSMNANTITK
::::::::::::
XP_011 SGKSMNANTITK
640
800 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 23:47:22 2016 done: Sat Nov 5 23:47:24 2016
Total Scan time: 15.500 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]