Result of FASTA (omim) for
pFN21AE4556
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE4556, 677 aa
1>>>pF1KE4556 677 - 677 aa - 677 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.6003+/-0.000351; mu= 18.1989+/- 0.022
mean_var=70.8039+/-14.227, 0's: 0 Z-trim(115.5): 4 B-trim: 241 in 2/51
Lambda= 0.152421
statistics sampled from 26073 (26077) to 26073 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.66), E-opt: 0.2 (0.306), width: 16
Scan time: 9.170
The best scores are: opt bits E(85289)
NP_000395 (OMIM: 230500,230600,230650,253010,61145 ( 677) 4684 1039.3 0
NP_001303969 (OMIM: 230500,230600,230650,253010,61 ( 725) 4538 1007.2 0
NP_001073279 (OMIM: 230500,230600,230650,253010,61 ( 647) 4507 1000.4 0
NP_001129074 (OMIM: 230500,230600,230650,253010,61 ( 546) 3000 669.0 1.3e-191
>>NP_000395 (OMIM: 230500,230600,230650,253010,611458) b (677 aa)
initn: 4684 init1: 4684 opt: 4684 Z-score: 5560.8 bits: 1039.3 E(85289): 0
Smith-Waterman score: 4684; 99.9% identity (99.9% similar) in 677 aa overlap (1-677:1-677)
10 20 30 40 50 60
pF1KE4 MPGFLVRILLLLLVLLLLGPTRGLRNATQRMFEIDYSRDSFLKDGQPFRYISGSIHYSRV
::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MPGFLVRILPLLLVLLLLGPTRGLRNATQRMFEIDYSRDSFLKDGQPFRYISGSIHYSRV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 PRFYWKDRLLKMKMAGLNAIQTYVPWNFHEPWPGQYQFSEDHDVEYFLRLAHELGLLVIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 PRFYWKDRLLKMKMAGLNAIQTYVPWNFHEPWPGQYQFSEDHDVEYFLRLAHELGLLVIL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 RPGPYICAEWEMGGLPAWLLEKESILLRSSDPDYLAAVDKWLGVLLPKMKPLLYQNGGPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 RPGPYICAEWEMGGLPAWLLEKESILLRSSDPDYLAAVDKWLGVLLPKMKPLLYQNGGPV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 ITVQVENEYGSYFACDFDYLRFLQKRFRHHLGDDVVLFTTDGAHKTFLKCGALQGLYTTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 ITVQVENEYGSYFACDFDYLRFLQKRFRHHLGDDVVLFTTDGAHKTFLKCGALQGLYTTV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 DFGTGSNITDAFLSQRKCEPKGPLINSEFYTGWLDHWGQPHSTIKTEAVASSLYDILARG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 DFGTGSNITDAFLSQRKCEPKGPLINSEFYTGWLDHWGQPHSTIKTEAVASSLYDILARG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 ASVNLYMFIGGTNFAYWNGANSPYAAQPTSYDYDAPLSEAGDLTEKYFALRNIIQKFEKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 ASVNLYMFIGGTNFAYWNGANSPYAAQPTSYDYDAPLSEAGDLTEKYFALRNIIQKFEKV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 PEGPIPPSTPKFAYGKVTLEKLKTVGAALDILCPSGPIKSLYPLTFIQVKQHYGFVLYRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 PEGPIPPSTPKFAYGKVTLEKLKTVGAALDILCPSGPIKSLYPLTFIQVKQHYGFVLYRT
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE4 TLPQDCSNPAPLSSPLNGVHDRAYVAVDGIPQGVLERNNVITLNITGKAGATLDLLVENM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 TLPQDCSNPAPLSSPLNGVHDRAYVAVDGIPQGVLERNNVITLNITGKAGATLDLLVENM
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE4 GRVNYGAYINDFKGLVSNLTLSSNILTDWTIFPLDTEDAVRSHLGGWGHRDSGHHDEAWA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 GRVNYGAYINDFKGLVSNLTLSSNILTDWTIFPLDTEDAVRSHLGGWGHRDSGHHDEAWA
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE4 HNSSNYTLPAFYMGNFSIPSGIPDLPQDTFIQFPGWTKGQVWINGFNLGRYWPARGPQLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 HNSSNYTLPAFYMGNFSIPSGIPDLPQDTFIQFPGWTKGQVWINGFNLGRYWPARGPQLT
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE4 LFVPQHILMTSAPNTITVLELEWAPCSSDDPELCAVTFVDRPVIGSSVTYDHPSKPVEKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LFVPQHILMTSAPNTITVLELEWAPCSSDDPELCAVTFVDRPVIGSSVTYDHPSKPVEKR
610 620 630 640 650 660
670
pF1KE4 LMPPPPQKNKDSWLDHV
:::::::::::::::::
NP_000 LMPPPPQKNKDSWLDHV
670
>>NP_001303969 (OMIM: 230500,230600,230650,253010,611458 (725 aa)
initn: 4538 init1: 4538 opt: 4538 Z-score: 5386.8 bits: 1007.2 E(85289): 0
Smith-Waterman score: 4538; 100.0% identity (100.0% similar) in 652 aa overlap (26-677:74-725)
10 20 30 40 50
pF1KE4 MPGFLVRILLLLLVLLLLGPTRGLRNATQRMFEIDYSRDSFLKDGQPFRYISGSI
::::::::::::::::::::::::::::::
NP_001 LPLHKRGTKTAPNEHASSNRSGRRRRRQQWNATQRMFEIDYSRDSFLKDGQPFRYISGSI
50 60 70 80 90 100
60 70 80 90 100 110
pF1KE4 HYSRVPRFYWKDRLLKMKMAGLNAIQTYVPWNFHEPWPGQYQFSEDHDVEYFLRLAHELG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HYSRVPRFYWKDRLLKMKMAGLNAIQTYVPWNFHEPWPGQYQFSEDHDVEYFLRLAHELG
110 120 130 140 150 160
120 130 140 150 160 170
pF1KE4 LLVILRPGPYICAEWEMGGLPAWLLEKESILLRSSDPDYLAAVDKWLGVLLPKMKPLLYQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLVILRPGPYICAEWEMGGLPAWLLEKESILLRSSDPDYLAAVDKWLGVLLPKMKPLLYQ
170 180 190 200 210 220
180 190 200 210 220 230
pF1KE4 NGGPVITVQVENEYGSYFACDFDYLRFLQKRFRHHLGDDVVLFTTDGAHKTFLKCGALQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NGGPVITVQVENEYGSYFACDFDYLRFLQKRFRHHLGDDVVLFTTDGAHKTFLKCGALQG
230 240 250 260 270 280
240 250 260 270 280 290
pF1KE4 LYTTVDFGTGSNITDAFLSQRKCEPKGPLINSEFYTGWLDHWGQPHSTIKTEAVASSLYD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LYTTVDFGTGSNITDAFLSQRKCEPKGPLINSEFYTGWLDHWGQPHSTIKTEAVASSLYD
290 300 310 320 330 340
300 310 320 330 340 350
pF1KE4 ILARGASVNLYMFIGGTNFAYWNGANSPYAAQPTSYDYDAPLSEAGDLTEKYFALRNIIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ILARGASVNLYMFIGGTNFAYWNGANSPYAAQPTSYDYDAPLSEAGDLTEKYFALRNIIQ
350 360 370 380 390 400
360 370 380 390 400 410
pF1KE4 KFEKVPEGPIPPSTPKFAYGKVTLEKLKTVGAALDILCPSGPIKSLYPLTFIQVKQHYGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KFEKVPEGPIPPSTPKFAYGKVTLEKLKTVGAALDILCPSGPIKSLYPLTFIQVKQHYGF
410 420 430 440 450 460
420 430 440 450 460 470
pF1KE4 VLYRTTLPQDCSNPAPLSSPLNGVHDRAYVAVDGIPQGVLERNNVITLNITGKAGATLDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLYRTTLPQDCSNPAPLSSPLNGVHDRAYVAVDGIPQGVLERNNVITLNITGKAGATLDL
470 480 490 500 510 520
480 490 500 510 520 530
pF1KE4 LVENMGRVNYGAYINDFKGLVSNLTLSSNILTDWTIFPLDTEDAVRSHLGGWGHRDSGHH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LVENMGRVNYGAYINDFKGLVSNLTLSSNILTDWTIFPLDTEDAVRSHLGGWGHRDSGHH
530 540 550 560 570 580
540 550 560 570 580 590
pF1KE4 DEAWAHNSSNYTLPAFYMGNFSIPSGIPDLPQDTFIQFPGWTKGQVWINGFNLGRYWPAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DEAWAHNSSNYTLPAFYMGNFSIPSGIPDLPQDTFIQFPGWTKGQVWINGFNLGRYWPAR
590 600 610 620 630 640
600 610 620 630 640 650
pF1KE4 GPQLTLFVPQHILMTSAPNTITVLELEWAPCSSDDPELCAVTFVDRPVIGSSVTYDHPSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GPQLTLFVPQHILMTSAPNTITVLELEWAPCSSDDPELCAVTFVDRPVIGSSVTYDHPSK
650 660 670 680 690 700
660 670
pF1KE4 PVEKRLMPPPPQKNKDSWLDHV
::::::::::::::::::::::
NP_001 PVEKRLMPPPPQKNKDSWLDHV
710 720
>>NP_001073279 (OMIM: 230500,230600,230650,253010,611458 (647 aa)
initn: 4507 init1: 4507 opt: 4507 Z-score: 5350.8 bits: 1000.4 E(85289): 0
Smith-Waterman score: 4507; 100.0% identity (100.0% similar) in 647 aa overlap (31-677:1-647)
10 20 30 40 50 60
pF1KE4 MPGFLVRILLLLLVLLLLGPTRGLRNATQRMFEIDYSRDSFLKDGQPFRYISGSIHYSRV
::::::::::::::::::::::::::::::
NP_001 MFEIDYSRDSFLKDGQPFRYISGSIHYSRV
10 20 30
70 80 90 100 110 120
pF1KE4 PRFYWKDRLLKMKMAGLNAIQTYVPWNFHEPWPGQYQFSEDHDVEYFLRLAHELGLLVIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PRFYWKDRLLKMKMAGLNAIQTYVPWNFHEPWPGQYQFSEDHDVEYFLRLAHELGLLVIL
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE4 RPGPYICAEWEMGGLPAWLLEKESILLRSSDPDYLAAVDKWLGVLLPKMKPLLYQNGGPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RPGPYICAEWEMGGLPAWLLEKESILLRSSDPDYLAAVDKWLGVLLPKMKPLLYQNGGPV
100 110 120 130 140 150
190 200 210 220 230 240
pF1KE4 ITVQVENEYGSYFACDFDYLRFLQKRFRHHLGDDVVLFTTDGAHKTFLKCGALQGLYTTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ITVQVENEYGSYFACDFDYLRFLQKRFRHHLGDDVVLFTTDGAHKTFLKCGALQGLYTTV
160 170 180 190 200 210
250 260 270 280 290 300
pF1KE4 DFGTGSNITDAFLSQRKCEPKGPLINSEFYTGWLDHWGQPHSTIKTEAVASSLYDILARG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DFGTGSNITDAFLSQRKCEPKGPLINSEFYTGWLDHWGQPHSTIKTEAVASSLYDILARG
220 230 240 250 260 270
310 320 330 340 350 360
pF1KE4 ASVNLYMFIGGTNFAYWNGANSPYAAQPTSYDYDAPLSEAGDLTEKYFALRNIIQKFEKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ASVNLYMFIGGTNFAYWNGANSPYAAQPTSYDYDAPLSEAGDLTEKYFALRNIIQKFEKV
280 290 300 310 320 330
370 380 390 400 410 420
pF1KE4 PEGPIPPSTPKFAYGKVTLEKLKTVGAALDILCPSGPIKSLYPLTFIQVKQHYGFVLYRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PEGPIPPSTPKFAYGKVTLEKLKTVGAALDILCPSGPIKSLYPLTFIQVKQHYGFVLYRT
340 350 360 370 380 390
430 440 450 460 470 480
pF1KE4 TLPQDCSNPAPLSSPLNGVHDRAYVAVDGIPQGVLERNNVITLNITGKAGATLDLLVENM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TLPQDCSNPAPLSSPLNGVHDRAYVAVDGIPQGVLERNNVITLNITGKAGATLDLLVENM
400 410 420 430 440 450
490 500 510 520 530 540
pF1KE4 GRVNYGAYINDFKGLVSNLTLSSNILTDWTIFPLDTEDAVRSHLGGWGHRDSGHHDEAWA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GRVNYGAYINDFKGLVSNLTLSSNILTDWTIFPLDTEDAVRSHLGGWGHRDSGHHDEAWA
460 470 480 490 500 510
550 560 570 580 590 600
pF1KE4 HNSSNYTLPAFYMGNFSIPSGIPDLPQDTFIQFPGWTKGQVWINGFNLGRYWPARGPQLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HNSSNYTLPAFYMGNFSIPSGIPDLPQDTFIQFPGWTKGQVWINGFNLGRYWPARGPQLT
520 530 540 550 560 570
610 620 630 640 650 660
pF1KE4 LFVPQHILMTSAPNTITVLELEWAPCSSDDPELCAVTFVDRPVIGSSVTYDHPSKPVEKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LFVPQHILMTSAPNTITVLELEWAPCSSDDPELCAVTFVDRPVIGSSVTYDHPSKPVEKR
580 590 600 610 620 630
670
pF1KE4 LMPPPPQKNKDSWLDHV
:::::::::::::::::
NP_001 LMPPPPQKNKDSWLDHV
640
>>NP_001129074 (OMIM: 230500,230600,230650,253010,611458 (546 aa)
initn: 3520 init1: 3000 opt: 3000 Z-score: 3560.9 bits: 669.0 E(85289): 1.3e-191
Smith-Waterman score: 3290; 77.4% identity (79.0% similar) in 677 aa overlap (1-677:1-546)
10 20 30 40 50 60
pF1KE4 MPGFLVRILLLLLVLLLLGPTRGLRNATQRMFEIDYSRDSFLKDGQPFRYISGSIHYSRV
::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPGFLVRILPLLLVLLLLGPTRGLRNATQRMFEIDYSRDSFLKDGQPFRYISGSIHYSRV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 PRFYWKDRLLKMKMAGLNAIQTYVPWNFHEPWPGQYQFSEDHDVEYFLRLAHELGLLVIL
:::::::::::::::::::::: ::.
NP_001 PRFYWKDRLLKMKMAGLNAIQTL---------PGS-------------------------
70 80
130 140 150 160 170 180
pF1KE4 RPGPYICAEWEMGGLPAWLLEKESILLRSSDPDYLAAVDKWLGVLLPKMKPLLYQNGGPV
:.. . : : : : . ...:
NP_001 ------CGQ--VVGSP-------------SAQDEASPLSEW-------------------
90 100
190 200 210 220 230 240
pF1KE4 ITVQVENEYGSYFACDFDYLRFLQKRFRHHLGDDVVLFTTDGAHKTFLKCGALQGLYTTV
. :.:
NP_001 -----RASYNS-------------------------------------------------
110
250 260 270 280 290 300
pF1KE4 DFGTGSNITDAFLSQRKCEPKGPLINSEFYTGWLDHWGQPHSTIKTEAVASSLYDILARG
.::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ---AGSNITDAFLSQRKCEPKGPLINSEFYTGWLDHWGQPHSTIKTEAVASSLYDILARG
120 130 140 150 160
310 320 330 340 350 360
pF1KE4 ASVNLYMFIGGTNFAYWNGANSPYAAQPTSYDYDAPLSEAGDLTEKYFALRNIIQKFEKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ASVNLYMFIGGTNFAYWNGANSPYAAQPTSYDYDAPLSEAGDLTEKYFALRNIIQKFEKV
170 180 190 200 210 220
370 380 390 400 410 420
pF1KE4 PEGPIPPSTPKFAYGKVTLEKLKTVGAALDILCPSGPIKSLYPLTFIQVKQHYGFVLYRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PEGPIPPSTPKFAYGKVTLEKLKTVGAALDILCPSGPIKSLYPLTFIQVKQHYGFVLYRT
230 240 250 260 270 280
430 440 450 460 470 480
pF1KE4 TLPQDCSNPAPLSSPLNGVHDRAYVAVDGIPQGVLERNNVITLNITGKAGATLDLLVENM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TLPQDCSNPAPLSSPLNGVHDRAYVAVDGIPQGVLERNNVITLNITGKAGATLDLLVENM
290 300 310 320 330 340
490 500 510 520 530 540
pF1KE4 GRVNYGAYINDFKGLVSNLTLSSNILTDWTIFPLDTEDAVRSHLGGWGHRDSGHHDEAWA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GRVNYGAYINDFKGLVSNLTLSSNILTDWTIFPLDTEDAVRSHLGGWGHRDSGHHDEAWA
350 360 370 380 390 400
550 560 570 580 590 600
pF1KE4 HNSSNYTLPAFYMGNFSIPSGIPDLPQDTFIQFPGWTKGQVWINGFNLGRYWPARGPQLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HNSSNYTLPAFYMGNFSIPSGIPDLPQDTFIQFPGWTKGQVWINGFNLGRYWPARGPQLT
410 420 430 440 450 460
610 620 630 640 650 660
pF1KE4 LFVPQHILMTSAPNTITVLELEWAPCSSDDPELCAVTFVDRPVIGSSVTYDHPSKPVEKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LFVPQHILMTSAPNTITVLELEWAPCSSDDPELCAVTFVDRPVIGSSVTYDHPSKPVEKR
470 480 490 500 510 520
670
pF1KE4 LMPPPPQKNKDSWLDHV
:::::::::::::::::
NP_001 LMPPPPQKNKDSWLDHV
530 540
677 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 23:58:14 2016 done: Sat Nov 5 23:58:15 2016
Total Scan time: 9.170 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]