Result of FASTA (omim) for
pFN21AE4553
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE4553, 665 aa
1>>>pF1KE4553 665 - 665 aa - 665 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.8521+/-0.000363; mu= 13.7985+/- 0.023
mean_var=130.0060+/-25.959, 0's: 0 Z-trim(117.8): 270 B-trim: 24 in 1/55
Lambda= 0.112484
statistics sampled from 29852 (30125) to 29852 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.702), E-opt: 0.2 (0.353), width: 16
Scan time: 11.640
The best scores are: opt bits E(85289)
NP_015556 (OMIM: 603213,603546) kinesin-like prote ( 665) 4328 714.0 4.5e-205
NP_001243198 (OMIM: 603213,603546) kinesin-like pr ( 597) 3875 640.4 5.5e-183
NP_001243199 (OMIM: 603213,603546) kinesin-like pr ( 597) 3875 640.4 5.5e-183
NP_112494 (OMIM: 611271) kinesin-like protein KIF1 ( 898) 735 131.0 1.9e-29
XP_016873868 (OMIM: 611271) PREDICTED: kinesin-lik ( 898) 735 131.0 1.9e-29
XP_006714589 (OMIM: 604683) PREDICTED: kinesin-lik ( 724) 728 129.8 3.5e-29
NP_001287720 (OMIM: 604683) kinesin-like protein K ( 726) 728 129.8 3.5e-29
XP_011522693 (OMIM: 614570) PREDICTED: kinesin-lik ( 437) 720 128.3 5.8e-29
XP_011522689 (OMIM: 614570) PREDICTED: kinesin-lik ( 864) 721 128.7 8.8e-29
NP_001251503 (OMIM: 614570) kinesin-like protein K ( 833) 720 128.5 9.6e-29
XP_011522691 (OMIM: 614570) PREDICTED: kinesin-lik ( 842) 720 128.5 9.6e-29
XP_011522688 (OMIM: 614570) PREDICTED: kinesin-lik ( 864) 720 128.6 9.8e-29
XP_011522687 (OMIM: 614570) PREDICTED: kinesin-lik ( 873) 720 128.6 9.9e-29
NP_001252506 (OMIM: 614570) kinesin-like protein K ( 852) 713 127.4 2.1e-28
XP_011522690 (OMIM: 614570) PREDICTED: kinesin-lik ( 861) 713 127.4 2.2e-28
XP_016864485 (OMIM: 604683) PREDICTED: kinesin-lik ( 697) 702 125.6 6.3e-28
NP_008985 (OMIM: 604683) kinesin-like protein KIF3 ( 699) 702 125.6 6.3e-28
XP_016864484 (OMIM: 604683) PREDICTED: kinesin-lik ( 700) 702 125.6 6.3e-28
NP_001287721 (OMIM: 604683) kinesin-like protein K ( 702) 702 125.6 6.3e-28
NP_001092763 (OMIM: 609184) chromosome-associated (1234) 703 125.9 8.8e-28
NP_036442 (OMIM: 300521,300923) chromosome-associa (1232) 695 124.6 2.2e-27
NP_004789 (OMIM: 603754) kinesin-like protein KIF3 ( 747) 690 123.6 2.6e-27
NP_004512 (OMIM: 602809) kinesin-1 heavy chain [Ho ( 963) 678 121.8 1.2e-26
NP_004975 (OMIM: 602821,604187) kinesin heavy chai (1032) 669 120.3 3.5e-26
XP_016863148 (OMIM: 117143,616051) PREDICTED: cent (2551) 669 120.6 7e-26
XP_011529851 (OMIM: 117143,616051) PREDICTED: cent (2553) 669 120.6 7e-26
NP_001273663 (OMIM: 117143,616051) centromere-asso (2580) 669 120.6 7.1e-26
XP_011529850 (OMIM: 117143,616051) PREDICTED: cent (2604) 669 120.6 7.1e-26
XP_011529849 (OMIM: 117143,616051) PREDICTED: cent (2605) 669 120.6 7.1e-26
XP_011529848 (OMIM: 117143,616051) PREDICTED: cent (2633) 669 120.6 7.2e-26
XP_011529847 (OMIM: 117143,616051) PREDICTED: cent (2648) 669 120.6 7.2e-26
XP_011529846 (OMIM: 117143,616051) PREDICTED: cent (2676) 669 120.6 7.3e-26
NP_001804 (OMIM: 117143,616051) centromere-associa (2701) 669 120.7 7.3e-26
XP_005246008 (OMIM: 605037) PREDICTED: kinesin-lik ( 984) 661 119.0 8.3e-26
XP_005246007 (OMIM: 605037) PREDICTED: kinesin-lik ( 985) 661 119.0 8.3e-26
XP_011540147 (OMIM: 605037) PREDICTED: kinesin-lik ( 992) 661 119.0 8.3e-26
XP_011540146 (OMIM: 605037) PREDICTED: kinesin-lik ( 997) 661 119.0 8.4e-26
XP_011540145 (OMIM: 605037) PREDICTED: kinesin-lik (1017) 661 119.0 8.5e-26
NP_001116291 (OMIM: 605037) kinesin-like protein K (1028) 661 119.0 8.6e-26
NP_065867 (OMIM: 605037) kinesin-like protein KIF1 (1029) 661 119.0 8.6e-26
XP_011540144 (OMIM: 605037) PREDICTED: kinesin-lik (1031) 661 119.0 8.6e-26
XP_011540143 (OMIM: 605037) PREDICTED: kinesin-lik (1038) 661 119.0 8.6e-26
XP_011540142 (OMIM: 605037) PREDICTED: kinesin-lik (1042) 661 119.0 8.7e-26
XP_011540141 (OMIM: 605037) PREDICTED: kinesin-lik (1043) 661 119.0 8.7e-26
XP_011540140 (OMIM: 605037) PREDICTED: kinesin-lik (1062) 661 119.0 8.8e-26
XP_011540139 (OMIM: 605037) PREDICTED: kinesin-lik (1063) 661 119.0 8.8e-26
XP_011521380 (OMIM: 604535) PREDICTED: kinesin-lik ( 694) 656 118.1 1.1e-25
XP_011521381 (OMIM: 604535) PREDICTED: kinesin-lik ( 694) 656 118.1 1.1e-25
XP_016878715 (OMIM: 604535) PREDICTED: kinesin-lik ( 775) 656 118.1 1.2e-25
XP_005256001 (OMIM: 604535) PREDICTED: kinesin-lik ( 775) 656 118.1 1.2e-25
>>NP_015556 (OMIM: 603213,603546) kinesin-like protein K (665 aa)
initn: 4328 init1: 4328 opt: 4328 Z-score: 3802.8 bits: 714.0 E(85289): 4.5e-205
Smith-Waterman score: 4328; 100.0% identity (100.0% similar) in 665 aa overlap (1-665:1-665)
10 20 30 40 50 60
pF1KE4 MAAGGSTQQRRREMAAASAAAISGAGRCRLSKIGATRRPPPARVRVAVRLRPFVDGTAGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_015 MAAGGSTQQRRREMAAASAAAISGAGRCRLSKIGATRRPPPARVRVAVRLRPFVDGTAGA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 SDPPCVRGMDSCSLEIANWRNHQETLKYQFDAFYGERSTQQDIYAGSVQPILRHLLEGQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_015 SDPPCVRGMDSCSLEIANWRNHQETLKYQFDAFYGERSTQQDIYAGSVQPILRHLLEGQN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 ASVLAYGPTGAGKTHTMLGSPEQPGVIPRALMDLLQLTREEGAEGRPWALSVTMSYLEIY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_015 ASVLAYGPTGAGKTHTMLGSPEQPGVIPRALMDLLQLTREEGAEGRPWALSVTMSYLEIY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 QEKVLDLLDPASGDLVIREDCRGNILIPGLSQKPISSFADFERHFLPASRNRTVGATRLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_015 QEKVLDLLDPASGDLVIREDCRGNILIPGLSQKPISSFADFERHFLPASRNRTVGATRLN
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 QRSSRSHAVLLVKVDQRERLAPFRQREGKLYLIDLAGSEDNRRTGNKGLRLKESGAINTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_015 QRSSRSHAVLLVKVDQRERLAPFRQREGKLYLIDLAGSEDNRRTGNKGLRLKESGAINTS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 LFVLGKVVDALNQGLPRVPYRDSKLTRLLQDSLGGSAHSILIANIAPERRFYLDTVSALN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_015 LFVLGKVVDALNQGLPRVPYRDSKLTRLLQDSLGGSAHSILIANIAPERRFYLDTVSALN
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 FAARSKEVINRPFTNESLQPHALGPVKLSQKELLGPPEAKRARGPEEEEIGSPEPMAAPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_015 FAARSKEVINRPFTNESLQPHALGPVKLSQKELLGPPEAKRARGPEEEEIGSPEPMAAPA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE4 SASQKLSPLQKLSSMDPAMLERLLSLDRLLASQGSQGAPLLSTPKRERMVLMKTVEEKDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_015 SASQKLSPLQKLSSMDPAMLERLLSLDRLLASQGSQGAPLLSTPKRERMVLMKTVEEKDL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE4 EIERLKTKQKELEAKMLAQKAEEKENHCPTMLRPLSHRTVTGAKPLKKAVVMPLQLIQEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_015 EIERLKTKQKELEAKMLAQKAEEKENHCPTMLRPLSHRTVTGAKPLKKAVVMPLQLIQEQ
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE4 AASPNAEIHILKNKGRKRKLESLDALEPEEKAEDCWELQISPELLAHGRQKILDLLNEGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_015 AASPNAEIHILKNKGRKRKLESLDALEPEEKAEDCWELQISPELLAHGRQKILDLLNEGS
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE4 ARDLRSLQRIGPKKAQLIVGWRELHGPFSQVEDLERVEGITGKQMESFLKANILGLAAGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_015 ARDLRSLQRIGPKKAQLIVGWRELHGPFSQVEDLERVEGITGKQMESFLKANILGLAAGQ
610 620 630 640 650 660
pF1KE4 RCGAS
:::::
NP_015 RCGAS
>>NP_001243198 (OMIM: 603213,603546) kinesin-like protei (597 aa)
initn: 3875 init1: 3875 opt: 3875 Z-score: 3406.1 bits: 640.4 E(85289): 5.5e-183
Smith-Waterman score: 3875; 100.0% identity (100.0% similar) in 597 aa overlap (69-665:1-597)
40 50 60 70 80 90
pF1KE4 PPPARVRVAVRLRPFVDGTAGASDPPCVRGMDSCSLEIANWRNHQETLKYQFDAFYGERS
::::::::::::::::::::::::::::::
NP_001 MDSCSLEIANWRNHQETLKYQFDAFYGERS
10 20 30
100 110 120 130 140 150
pF1KE4 TQQDIYAGSVQPILRHLLEGQNASVLAYGPTGAGKTHTMLGSPEQPGVIPRALMDLLQLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TQQDIYAGSVQPILRHLLEGQNASVLAYGPTGAGKTHTMLGSPEQPGVIPRALMDLLQLT
40 50 60 70 80 90
160 170 180 190 200 210
pF1KE4 REEGAEGRPWALSVTMSYLEIYQEKVLDLLDPASGDLVIREDCRGNILIPGLSQKPISSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 REEGAEGRPWALSVTMSYLEIYQEKVLDLLDPASGDLVIREDCRGNILIPGLSQKPISSF
100 110 120 130 140 150
220 230 240 250 260 270
pF1KE4 ADFERHFLPASRNRTVGATRLNQRSSRSHAVLLVKVDQRERLAPFRQREGKLYLIDLAGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ADFERHFLPASRNRTVGATRLNQRSSRSHAVLLVKVDQRERLAPFRQREGKLYLIDLAGS
160 170 180 190 200 210
280 290 300 310 320 330
pF1KE4 EDNRRTGNKGLRLKESGAINTSLFVLGKVVDALNQGLPRVPYRDSKLTRLLQDSLGGSAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EDNRRTGNKGLRLKESGAINTSLFVLGKVVDALNQGLPRVPYRDSKLTRLLQDSLGGSAH
220 230 240 250 260 270
340 350 360 370 380 390
pF1KE4 SILIANIAPERRFYLDTVSALNFAARSKEVINRPFTNESLQPHALGPVKLSQKELLGPPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SILIANIAPERRFYLDTVSALNFAARSKEVINRPFTNESLQPHALGPVKLSQKELLGPPE
280 290 300 310 320 330
400 410 420 430 440 450
pF1KE4 AKRARGPEEEEIGSPEPMAAPASASQKLSPLQKLSSMDPAMLERLLSLDRLLASQGSQGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AKRARGPEEEEIGSPEPMAAPASASQKLSPLQKLSSMDPAMLERLLSLDRLLASQGSQGA
340 350 360 370 380 390
460 470 480 490 500 510
pF1KE4 PLLSTPKRERMVLMKTVEEKDLEIERLKTKQKELEAKMLAQKAEEKENHCPTMLRPLSHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PLLSTPKRERMVLMKTVEEKDLEIERLKTKQKELEAKMLAQKAEEKENHCPTMLRPLSHR
400 410 420 430 440 450
520 530 540 550 560 570
pF1KE4 TVTGAKPLKKAVVMPLQLIQEQAASPNAEIHILKNKGRKRKLESLDALEPEEKAEDCWEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TVTGAKPLKKAVVMPLQLIQEQAASPNAEIHILKNKGRKRKLESLDALEPEEKAEDCWEL
460 470 480 490 500 510
580 590 600 610 620 630
pF1KE4 QISPELLAHGRQKILDLLNEGSARDLRSLQRIGPKKAQLIVGWRELHGPFSQVEDLERVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QISPELLAHGRQKILDLLNEGSARDLRSLQRIGPKKAQLIVGWRELHGPFSQVEDLERVE
520 530 540 550 560 570
640 650 660
pF1KE4 GITGKQMESFLKANILGLAAGQRCGAS
:::::::::::::::::::::::::::
NP_001 GITGKQMESFLKANILGLAAGQRCGAS
580 590
>>NP_001243199 (OMIM: 603213,603546) kinesin-like protei (597 aa)
initn: 3875 init1: 3875 opt: 3875 Z-score: 3406.1 bits: 640.4 E(85289): 5.5e-183
Smith-Waterman score: 3875; 100.0% identity (100.0% similar) in 597 aa overlap (69-665:1-597)
40 50 60 70 80 90
pF1KE4 PPPARVRVAVRLRPFVDGTAGASDPPCVRGMDSCSLEIANWRNHQETLKYQFDAFYGERS
::::::::::::::::::::::::::::::
NP_001 MDSCSLEIANWRNHQETLKYQFDAFYGERS
10 20 30
100 110 120 130 140 150
pF1KE4 TQQDIYAGSVQPILRHLLEGQNASVLAYGPTGAGKTHTMLGSPEQPGVIPRALMDLLQLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TQQDIYAGSVQPILRHLLEGQNASVLAYGPTGAGKTHTMLGSPEQPGVIPRALMDLLQLT
40 50 60 70 80 90
160 170 180 190 200 210
pF1KE4 REEGAEGRPWALSVTMSYLEIYQEKVLDLLDPASGDLVIREDCRGNILIPGLSQKPISSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 REEGAEGRPWALSVTMSYLEIYQEKVLDLLDPASGDLVIREDCRGNILIPGLSQKPISSF
100 110 120 130 140 150
220 230 240 250 260 270
pF1KE4 ADFERHFLPASRNRTVGATRLNQRSSRSHAVLLVKVDQRERLAPFRQREGKLYLIDLAGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ADFERHFLPASRNRTVGATRLNQRSSRSHAVLLVKVDQRERLAPFRQREGKLYLIDLAGS
160 170 180 190 200 210
280 290 300 310 320 330
pF1KE4 EDNRRTGNKGLRLKESGAINTSLFVLGKVVDALNQGLPRVPYRDSKLTRLLQDSLGGSAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EDNRRTGNKGLRLKESGAINTSLFVLGKVVDALNQGLPRVPYRDSKLTRLLQDSLGGSAH
220 230 240 250 260 270
340 350 360 370 380 390
pF1KE4 SILIANIAPERRFYLDTVSALNFAARSKEVINRPFTNESLQPHALGPVKLSQKELLGPPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SILIANIAPERRFYLDTVSALNFAARSKEVINRPFTNESLQPHALGPVKLSQKELLGPPE
280 290 300 310 320 330
400 410 420 430 440 450
pF1KE4 AKRARGPEEEEIGSPEPMAAPASASQKLSPLQKLSSMDPAMLERLLSLDRLLASQGSQGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AKRARGPEEEEIGSPEPMAAPASASQKLSPLQKLSSMDPAMLERLLSLDRLLASQGSQGA
340 350 360 370 380 390
460 470 480 490 500 510
pF1KE4 PLLSTPKRERMVLMKTVEEKDLEIERLKTKQKELEAKMLAQKAEEKENHCPTMLRPLSHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PLLSTPKRERMVLMKTVEEKDLEIERLKTKQKELEAKMLAQKAEEKENHCPTMLRPLSHR
400 410 420 430 440 450
520 530 540 550 560 570
pF1KE4 TVTGAKPLKKAVVMPLQLIQEQAASPNAEIHILKNKGRKRKLESLDALEPEEKAEDCWEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TVTGAKPLKKAVVMPLQLIQEQAASPNAEIHILKNKGRKRKLESLDALEPEEKAEDCWEL
460 470 480 490 500 510
580 590 600 610 620 630
pF1KE4 QISPELLAHGRQKILDLLNEGSARDLRSLQRIGPKKAQLIVGWRELHGPFSQVEDLERVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QISPELLAHGRQKILDLLNEGSARDLRSLQRIGPKKAQLIVGWRELHGPFSQVEDLERVE
520 530 540 550 560 570
640 650 660
pF1KE4 GITGKQMESFLKANILGLAAGQRCGAS
:::::::::::::::::::::::::::
NP_001 GITGKQMESFLKANILGLAAGQRCGAS
580 590
>>NP_112494 (OMIM: 611271) kinesin-like protein KIF18A [ (898 aa)
initn: 780 init1: 260 opt: 735 Z-score: 649.8 bits: 131.0 E(85289): 1.9e-29
Smith-Waterman score: 752; 30.8% identity (59.5% similar) in 587 aa overlap (28-575:9-585)
10 20 30 40 50
pF1KE4 MAAGGSTQQRRREMAAASAAAISGAGRCRLSKIGATRRPPPARVRVAV--RLRPFVDGTA
:. :. . :: .. ..: .. ::
NP_112 MSVTEEDLCHHMKVVVRVRPENTKEKAAGFHKVVHVVDKHI
10 20 30 40
60 70 80 90 100 110
pF1KE4 GASDPP-----CVRGMDSCSLEIANWRNHQETLKYQFDAFYGERSTQQDIYAGSVQPILR
. :: .: . . .. . .:.. ::. ::: . : :::.... ...::::
NP_112 LVFDPKQEEVSFFHGKKTTNQNVIKKQNKD--LKFVFDAVFDETSTQSEVFEHTTKPILR
50 60 70 80 90
120 130 140 150 160 170
pF1KE4 HLLEGQNASVLAYGPTGAGKTHTMLGSPEQPGVIPRALMDLLQLTREEGAEGRPWALSVT
.:.: : .::::: :::::::::::: ..:::. ... : . : : :..
NP_112 SFLNGYNCTVLAYGATGAGKTHTMLGSADEPGVMYLTMLHLYKCMDEIKEEK---ICSTA
100 110 120 130 140 150
180 190 200 210 220 230
pF1KE4 MSYLEIYQEKVLDLLDPASGDLVIREDCRGNILIPGLS-QKPISSFADFERHFLP-ASRN
.::::.:.:.. ::: :: :..::: . .... ::. ..: :: . :.: ...:
NP_112 VSYLEVYNEQIRDLL-VNSGPLAVREDTQKGVVVHGLTLHQPKSSEEIL--HLLDNGNKN
160 170 180 190 200 210
240 250 260 270 280
pF1KE4 RTVGATRLNQRSSRSHAVLLVKVDQRERLAPFRQ--REGKLYLIDLAGSEDNRRTGNKGL
:: : .: :::::::. . . :... : . : : .:. :::::::: .: ::
NP_112 RTQHPTDMNATSSRSHAVFQIYLRQQDKTASINQNVRIAKMSLIDLAGSERASTSGAKGT
220 230 240 250 260 270
290 300 310 320 330 340
pF1KE4 RLKESGAINTSLFVLGKVVDALNQGLPR---VPYRDSKLTRLLQDSLGGSAHSILIANIA
:. :. :: ::..::.:..:: .. . .:::.:::::::.:::::. ..:.:: ..
NP_112 RFVEGTNINRSLLALGNVINALADSKRKNQHIPYRNSKLTRLLKDSLGGNCQTIMIAAVS
280 290 300 310 320 330
350 360 370 380 390
pF1KE4 PERRFYLDTVSALNFAARSKEVINRPFTNE-SLQPHALGPVKLSQ---------KELLGP
: :: :: ..:..: :.:.. . .: ... : ::. . :: :
NP_112 PSSVFYDDTYNTLKYANRAKDIKSSLKSNVLNVNNHITQYVKICNEQKAEILLLKEKLKA
340 350 360 370 380 390
400 410 420 430 440 450
pF1KE4 PEAKRARGPEEEE--IGSPEPMAAPASASQKLSPLQKLSSMDPAMLERLLSLDRLLASQG
: ..: :... . .:. :.. :. : . . .. :.:. :: .
NP_112 YEEQKAFTNENDQAKLMISNPQEKEIERFQEI--LNCLFQNREEIRQEYLKLEMLLKENE
400 410 420 430 440 450
460 470 480 490 500
pF1KE4 SQGAPLLSTPKRERMV-----LMKTVEEKDLEIERLKTKQKELEAKMLAQ--KAEEKENH
.. . :. .:. . :.. ..: .. :::... :: . . . .:. :
NP_112 LKSFYQQQCHKQIEMMCSEDKVEKATGKRDHRLAMLKTRRSYLEKRREEELKQFDENTNW
460 470 480 490 500 510
510 520 530 540 550 560
pF1KE4 CPTMLRPLSHRTVTGAKPLKKAVVMPLQLIQEQAASPNAEI-HILK----NKGRKRKLES
. . .. . .: : . . . .. : . .:.: :.. .. ..:. :.
NP_112 LHRVEKEMGLLSQNGHIPKELKKDLHCHHLHLQNKDLKAQIRHMMDLACLQEQQHRQTEA
520 530 540 550 560 570
570 580 590 600 610 620
pF1KE4 -LDALEPEEKAEDCWELQISPELLAHGRQKILDLLNEGSARDLRSLQRIGPKKAQLIVGW
:.:: : . . :
NP_112 VLNALLPTLRKQYCTLKEAGLSNAAFESDFKEIEHLVERKKVVVWADQTAEQPKQNDLPG
580 590 600 610 620 630
>>XP_016873868 (OMIM: 611271) PREDICTED: kinesin-like pr (898 aa)
initn: 780 init1: 260 opt: 735 Z-score: 649.8 bits: 131.0 E(85289): 1.9e-29
Smith-Waterman score: 752; 30.8% identity (59.5% similar) in 587 aa overlap (28-575:9-585)
10 20 30 40 50
pF1KE4 MAAGGSTQQRRREMAAASAAAISGAGRCRLSKIGATRRPPPARVRVAV--RLRPFVDGTA
:. :. . :: .. ..: .. ::
XP_016 MSVTEEDLCHHMKVVVRVRPENTKEKAAGFHKVVHVVDKHI
10 20 30 40
60 70 80 90 100 110
pF1KE4 GASDPP-----CVRGMDSCSLEIANWRNHQETLKYQFDAFYGERSTQQDIYAGSVQPILR
. :: .: . . .. . .:.. ::. ::: . : :::.... ...::::
XP_016 LVFDPKQEEVSFFHGKKTTNQNVIKKQNKD--LKFVFDAVFDETSTQSEVFEHTTKPILR
50 60 70 80 90
120 130 140 150 160 170
pF1KE4 HLLEGQNASVLAYGPTGAGKTHTMLGSPEQPGVIPRALMDLLQLTREEGAEGRPWALSVT
.:.: : .::::: :::::::::::: ..:::. ... : . : : :..
XP_016 SFLNGYNCTVLAYGATGAGKTHTMLGSADEPGVMYLTMLHLYKCMDEIKEEK---ICSTA
100 110 120 130 140 150
180 190 200 210 220 230
pF1KE4 MSYLEIYQEKVLDLLDPASGDLVIREDCRGNILIPGLS-QKPISSFADFERHFLP-ASRN
.::::.:.:.. ::: :: :..::: . .... ::. ..: :: . :.: ...:
XP_016 VSYLEVYNEQIRDLL-VNSGPLAVREDTQKGVVVHGLTLHQPKSSEEIL--HLLDNGNKN
160 170 180 190 200 210
240 250 260 270 280
pF1KE4 RTVGATRLNQRSSRSHAVLLVKVDQRERLAPFRQ--REGKLYLIDLAGSEDNRRTGNKGL
:: : .: :::::::. . . :... : . : : .:. :::::::: .: ::
XP_016 RTQHPTDMNATSSRSHAVFQIYLRQQDKTASINQNVRIAKMSLIDLAGSERASTSGAKGT
220 230 240 250 260 270
290 300 310 320 330 340
pF1KE4 RLKESGAINTSLFVLGKVVDALNQGLPR---VPYRDSKLTRLLQDSLGGSAHSILIANIA
:. :. :: ::..::.:..:: .. . .:::.:::::::.:::::. ..:.:: ..
XP_016 RFVEGTNINRSLLALGNVINALADSKRKNQHIPYRNSKLTRLLKDSLGGNCQTIMIAAVS
280 290 300 310 320 330
350 360 370 380 390
pF1KE4 PERRFYLDTVSALNFAARSKEVINRPFTNE-SLQPHALGPVKLSQ---------KELLGP
: :: :: ..:..: :.:.. . .: ... : ::. . :: :
XP_016 PSSVFYDDTYNTLKYANRAKDIKSSLKSNVLNVNNHITQYVKICNEQKAEILLLKEKLKA
340 350 360 370 380 390
400 410 420 430 440 450
pF1KE4 PEAKRARGPEEEE--IGSPEPMAAPASASQKLSPLQKLSSMDPAMLERLLSLDRLLASQG
: ..: :... . .:. :.. :. : . . .. :.:. :: .
XP_016 YEEQKAFTNENDQAKLMISNPQEKEIERFQEI--LNCLFQNREEIRQEYLKLEMLLKENE
400 410 420 430 440 450
460 470 480 490 500
pF1KE4 SQGAPLLSTPKRERMV-----LMKTVEEKDLEIERLKTKQKELEAKMLAQ--KAEEKENH
.. . :. .:. . :.. ..: .. :::... :: . . . .:. :
XP_016 LKSFYQQQCHKQIEMMCSEDKVEKATGKRDHRLAMLKTRRSYLEKRREEELKQFDENTNW
460 470 480 490 500 510
510 520 530 540 550 560
pF1KE4 CPTMLRPLSHRTVTGAKPLKKAVVMPLQLIQEQAASPNAEI-HILK----NKGRKRKLES
. . .. . .: : . . . .. : . .:.: :.. .. ..:. :.
XP_016 LHRVEKEMGLLSQNGHIPKELKKDLHCHHLHLQNKDLKAQIRHMMDLACLQEQQHRQTEA
520 530 540 550 560 570
570 580 590 600 610 620
pF1KE4 -LDALEPEEKAEDCWELQISPELLAHGRQKILDLLNEGSARDLRSLQRIGPKKAQLIVGW
:.:: : . . :
XP_016 VLNALLPTLRKQYCTLKEAGLSNAAFESDFKEIEHLVERKKVVVWADQTAEQPKQNDLPG
580 590 600 610 620 630
>>XP_006714589 (OMIM: 604683) PREDICTED: kinesin-like pr (724 aa)
initn: 684 init1: 202 opt: 728 Z-score: 644.9 bits: 129.8 E(85289): 3.5e-29
Smith-Waterman score: 736; 31.8% identity (59.1% similar) in 592 aa overlap (33-593:3-573)
10 20 30 40 50 60
pF1KE4 AGGSTQQRRREMAAASAAAISGAGRCRLSKIGATRRPPPA-RVRVAVRLRPFVDGTAGAS
:. ...: :.:.:: ::. . .
XP_006 MPINKSEKPESCDNVKVVVRCRPLNEREKSMC
10 20 30
70 80 90 100 110
pF1KE4 DPPCVRGMDSC--SLEIANWRNHQETLK-YQFDAFYGERSTQQDIYAGSVQPILRHLLEG
: ..: .. . . . .: : . ::. .: .: : :.: ...::. .:::
XP_006 YKQAV-SVDEMRGTITVHKTDSSNEPPKTFTFDTVFGPESKQLDVYNLTARPIIDSVLEG
40 50 60 70 80 90
120 130 140 150 160 170
pF1KE4 QNASVLAYGPTGAGKTHTMLGS---PEQPGVIPRALMDLL-QLTREEGAEGRPWALSVTM
:....::: ::.::: :: : :: :.:: .. .. .... :: . : . : .
XP_006 YNGTIFAYGQTGTGKTFTMEGVRAIPELRGIIPNSFAHIFGHIAKAEG-DTR---FLVRV
100 110 120 130 140
180 190 200 210 220 230
pF1KE4 SYLEIYQEKVLDLLDP-ASGDLVIREDCRGNILIPGLSQKPISSFADFERHFLPASRNRT
::::::.:.: ::: . : ..: .. : :: ... :..: . . .::.
XP_006 SYLEIYNEEVRDLLGKDQTQRLEVKERPDVGVYIKDLSAYVVNNADDMDRIMTLGHKNRS
150 160 170 180 190 200
240 250 260 270 280 290
pF1KE4 VGATRLNQRSSRSHAVLLVKVDQRERLAP--FRQREGKLYLIDLAGSEDNRRTGNKGLRL
:::: .:..::::::.. . .. :. .. : :::.:.:::::: . .:: : ::
XP_006 VGATNMNEHSSRSHAIFTITIECSEKGIDGNMHVRMGKLHLVDLAGSERQAKTGATGQRL
210 220 230 240 250 260
300 310 320 330 340 350
pF1KE4 KESGAINTSLFVLGKVVDALNQGLP-RVPYRDSKLTRLLQDSLGGSAHSILIANIAPERR
::. :: :: .::.:..:: .: .::::.:::::::::::::...... :::.:
XP_006 KEATKINLSLSTLGNVISALVDGKSTHVPYRNSKLTRLLQDSLGGNSKTMMCANIGPADY
270 280 290 300 310 320
360 370 380 390 400
pF1KE4 FYLDTVSALNFAARSKEVINRPFTNESLQPHALGPVKLSQKELLGP-PEAKRARGPE---
: .:.:.: .: :.:.. :. ::. . : . .:: :... : .
XP_006 NYDETISTLRYANRAKNIKNKARINEDPKDALLRQFQKEIEELKKKLEEGEEISGSDISG
330 340 350 360 370 380
410 420 430 440 450 460
pF1KE4 -EEEIGSPEPMAAPASASQKLSPLQKLSSMDP--AMLERLLSLDRLLASQGSQGAPLLST
::. .. . .: .. :: : ...:. ::..: .:. : .:
XP_006 SEEDDDEEGEVGEDGEKRKKRRGSSSSSSSDSTCSVIEK--PLDKFLPNQA--GKKKVS-
390 400 410 420 430 440
470 480 490 500 510
pF1KE4 PKRERMVLM--------KTVEEK-DLEIERLKTKQKELEAKMLAQ-KAEEKENHCPTMLR
: ..:. : :..: : :.: :. . . ::: . ::..... :
XP_006 P--DKMIEMQAKIDEERKALETKLDMEEEERNKARAELEKREKDLLKAQQEHQSLLEKLS
450 460 470 480 490 500
520 530 540 550 560 570
pF1KE4 PLSHRTVTGAKPLKKAVVMPLQLIQEQAASPNAEIHILKNKGR--KRKLESLDALEPEEK
: .....:. : . .:..:. : :.. ..... .:.:: : :..
XP_006 ALEKKVIVGGVDLLAKAEEQEKLLEES----NMELEERRKRAEQLRRELE-----EKEQE
510 520 530 540 550
580 590 600 610 620 630
pF1KE4 AEDCWELQISPELLAHGRQKILDLLNEGSARDLRSLQRIGPKKAQLIVGWRELHGPFSQV
: : : . :.:. : :
XP_006 RLDIEEKYTSLQEEAQGKTKKLKKVWTMLMAAKSEMADLQQEHQREIEGLLENIRQLSRE
560 570 580 590 600 610
>>NP_001287720 (OMIM: 604683) kinesin-like protein KIF3A (726 aa)
initn: 684 init1: 202 opt: 728 Z-score: 644.9 bits: 129.8 E(85289): 3.5e-29
Smith-Waterman score: 736; 31.8% identity (59.1% similar) in 592 aa overlap (33-593:3-573)
10 20 30 40 50 60
pF1KE4 AGGSTQQRRREMAAASAAAISGAGRCRLSKIGATRRPPPA-RVRVAVRLRPFVDGTAGAS
:. ...: :.:.:: ::. . .
NP_001 MPINKSEKPESCDNVKVVVRCRPLNEREKSMC
10 20 30
70 80 90 100 110
pF1KE4 DPPCVRGMDSC--SLEIANWRNHQETLK-YQFDAFYGERSTQQDIYAGSVQPILRHLLEG
: ..: .. . . . .: : . ::. .: .: : :.: ...::. .:::
NP_001 YKQAV-SVDEMRGTITVHKTDSSNEPPKTFTFDTVFGPESKQLDVYNLTARPIIDSVLEG
40 50 60 70 80 90
120 130 140 150 160 170
pF1KE4 QNASVLAYGPTGAGKTHTMLGS---PEQPGVIPRALMDLL-QLTREEGAEGRPWALSVTM
:....::: ::.::: :: : :: :.:: .. .. .... :: . : . : .
NP_001 YNGTIFAYGQTGTGKTFTMEGVRAIPELRGIIPNSFAHIFGHIAKAEG-DTR---FLVRV
100 110 120 130 140
180 190 200 210 220 230
pF1KE4 SYLEIYQEKVLDLLDP-ASGDLVIREDCRGNILIPGLSQKPISSFADFERHFLPASRNRT
::::::.:.: ::: . : ..: .. : :: ... :..: . . .::.
NP_001 SYLEIYNEEVRDLLGKDQTQRLEVKERPDVGVYIKDLSAYVVNNADDMDRIMTLGHKNRS
150 160 170 180 190 200
240 250 260 270 280 290
pF1KE4 VGATRLNQRSSRSHAVLLVKVDQRERLAP--FRQREGKLYLIDLAGSEDNRRTGNKGLRL
:::: .:..::::::.. . .. :. .. : :::.:.:::::: . .:: : ::
NP_001 VGATNMNEHSSRSHAIFTITIECSEKGIDGNMHVRMGKLHLVDLAGSERQAKTGATGQRL
210 220 230 240 250 260
300 310 320 330 340 350
pF1KE4 KESGAINTSLFVLGKVVDALNQGLP-RVPYRDSKLTRLLQDSLGGSAHSILIANIAPERR
::. :: :: .::.:..:: .: .::::.:::::::::::::...... :::.:
NP_001 KEATKINLSLSTLGNVISALVDGKSTHVPYRNSKLTRLLQDSLGGNSKTMMCANIGPADY
270 280 290 300 310 320
360 370 380 390 400
pF1KE4 FYLDTVSALNFAARSKEVINRPFTNESLQPHALGPVKLSQKELLGP-PEAKRARGPE---
: .:.:.: .: :.:.. :. ::. . : . .:: :... : .
NP_001 NYDETISTLRYANRAKNIKNKARINEDPKDALLRQFQKEIEELKKKLEEGEEISGSDISG
330 340 350 360 370 380
410 420 430 440 450 460
pF1KE4 -EEEIGSPEPMAAPASASQKLSPLQKLSSMDP--AMLERLLSLDRLLASQGSQGAPLLST
::. .. . .: .. :: : ...:. ::..: .:. : .:
NP_001 SEEDDDEEGEVGEDGEKRKKRRGSSSSSSSDSTCSVIEK--PLDKFLPNQA--GKKKVS-
390 400 410 420 430 440
470 480 490 500 510
pF1KE4 PKRERMVLM--------KTVEEK-DLEIERLKTKQKELEAKMLAQ-KAEEKENHCPTMLR
: ..:. : :..: : :.: :. . . ::: . ::..... :
NP_001 P--DKMIEMQAKIDEERKALETKLDMEEEERNKARAELEKREKDLLKAQQEHQSLLEKLS
450 460 470 480 490 500
520 530 540 550 560 570
pF1KE4 PLSHRTVTGAKPLKKAVVMPLQLIQEQAASPNAEIHILKNKGR--KRKLESLDALEPEEK
: .....:. : . .:..:. : :.. ..... .:.:: : :..
NP_001 ALEKKVIVGGVDLLAKAEEQEKLLEES----NMELEERRKRAEQLRRELE-----EKEQE
510 520 530 540 550
580 590 600 610 620 630
pF1KE4 AEDCWELQISPELLAHGRQKILDLLNEGSARDLRSLQRIGPKKAQLIVGWRELHGPFSQV
: : : . :.:. : :
NP_001 RLDIEEKYTSLQEEAQGKTKKLKKVWTMLMAAKSEMADLQQEHQREIEGLLENIRQLSRE
560 570 580 590 600 610
>>XP_011522693 (OMIM: 614570) PREDICTED: kinesin-like pr (437 aa)
initn: 630 init1: 220 opt: 720 Z-score: 640.9 bits: 128.3 E(85289): 5.8e-29
Smith-Waterman score: 720; 38.0% identity (65.2% similar) in 371 aa overlap (80-443:71-434)
50 60 70 80 90 100
pF1KE4 LRPFVDGTAGASDPPCVRGMDSCSLEIANWRNHQETLKYQFDAFYGERSTQQDIYAGSVQ
... . : . :: .:: .::::.. ...
XP_011 VVDERVLVFNPEEPDGGFPGLKWGGTHDGPKKKGKDLTFVFDRVFGEAATQQDVFQHTTH
50 60 70 80 90 100
110 120 130 140 150 160
pF1KE4 PILRHLLEGQNASVLAYGPTGAGKTHTMLGSPEQPGVIPRALMDLLQLTREEGAEGRPWA
.: .:.: : ::.::: ::::::::::: .::.. . ..: :. :. .
XP_011 SVLDSFLQGYNCSVFAYGATGAGKTHTMLGREGDPGIM---YLTTVELYRRLEARQQEKH
110 120 130 140 150
170 180 190 200 210 220
pF1KE4 LSVTMSYLEIYQEKVLDLLDPASGDLVIREDCRGNILIPGLS-QKPISSFADFERHFLPA
. : .:: :.:.:.. :::.: .: :.:::: .... ::: ..: :. .: . .
XP_011 FEVLISYQEVYNEQIHDLLEP-KGPLAIREDPDKGVVVQGLSFHQPASAEQLLEI-LTRG
160 170 180 190 200 210
230 240 250 260 270 280
pF1KE4 SRNRTVGATRLNQRSSRSHAVLLVKVDQRERLAPFRQ--REGKLYLIDLAGSEDNRRTGN
.:::: : : ::::::.. . : :..:. . : . .:. :::::::: :
XP_011 NRNRTQHPTDANATSSRSHAIFQIFVKQQDRVPGLTQAVQVAKMSLIDLAGSERASSTHA
220 230 240 250 260 270
290 300 310 320 330 340
pF1KE4 KGLRLKESGAINTSLFVLGKVVDALNQGLPR---VPYRDSKLTRLLQDSLGGSAHSILIA
:: ::.:.. :: ::..: .:..:: .. : ::::::::::::.:::::. ....::
XP_011 KGERLREGANINRSLLALINVLNALADAKGRKTHVPYRDSKLTRLLKDSLGGNCRTVMIA
280 290 300 310 320 330
350 360 370 380 390 400
pF1KE4 NIAPERRFYLDTVSALNFAARSKEV-INRPFTNESLQPHALGPVKLSQKELLGPPEAKRA
:.: : :: ..:..: :.::. .. . ::. : . . :. : . : :
XP_011 AISPSSLTYEDTYNTLKYADRAKEIRLSLKSNVTSLDCHISQYATICQQ-LQAEVAALRK
340 350 360 370 380 390
410 420 430 440 450 460
pF1KE4 RGPEEEEIGSPEPMAAPASASQKLSPLQKLSSMDPAMLERLLSLDRLLASQGSQGAPLLS
. : :.: :. :.: .. : ...... :. ..:
XP_011 KLQVYEGGGQPPPQDLPGSPKSGPPP-EQVKGLHPVPAQQLTVT
400 410 420 430
470 480 490 500 510 520
pF1KE4 TPKRERMVLMKTVEEKDLEIERLKTKQKELEAKMLAQKAEEKENHCPTMLRPLSHRTVTG
>>XP_011522689 (OMIM: 614570) PREDICTED: kinesin-like pr (864 aa)
initn: 525 init1: 220 opt: 721 Z-score: 637.7 bits: 128.7 E(85289): 8.8e-29
Smith-Waterman score: 729; 32.3% identity (57.3% similar) in 564 aa overlap (80-628:71-616)
50 60 70 80 90 100
pF1KE4 LRPFVDGTAGASDPPCVRGMDSCSLEIANWRNHQETLKYQFDAFYGERSTQQDIYAGSVQ
... . : . :: .:: .::::.. ...
XP_011 VVDERVLVFNPEEPDGGFPGLKWGGTHDGPKKKGKDLTFVFDRVFGEAATQQDVFQHTTH
50 60 70 80 90 100
110 120 130 140 150 160
pF1KE4 PILRHLLEGQNASVLAYGPTGAGKTHTMLGSPEQPGVIPRALMDLLQLTREEGAEGRPWA
.: .:.: : ::.::: ::::::::::: .::.. . ..: :. :. .
XP_011 SVLDSFLQGYNCSVFAYGATGAGKTHTMLGREGDPGIM---YLTTVELYRRLEARQQEKH
110 120 130 140 150
170 180 190 200 210 220
pF1KE4 LSVTMSYLEIYQEKVLDLLDPASGDLVIREDCRGNILIPGLS-QKPISSFADFERHFLPA
. : .:: :.:.:.. :::.: .: :.:::: .... ::: ..: :. .: . .
XP_011 FEVLISYQEVYNEQIHDLLEP-KGPLAIREDPDKGVVVQGLSFHQPASAEQLLEI-LTRG
160 170 180 190 200 210
230 240 250 260 270 280
pF1KE4 SRNRTVGATRLNQRSSRSHAVLLVKVDQRERLAPFRQ--REGKLYLIDLAGSEDNRRTGN
.:::: : : ::::::.. . : :..:. . : . .:. :::::::: :
XP_011 NRNRTQHPTDANATSSRSHAIFQIFVKQQDRVPGLTQAVQVAKMSLIDLAGSERASSTHA
220 230 240 250 260 270
290 300 310 320 330 340
pF1KE4 KGLRLKESGAINTSLFVLGKVVDALNQGLPR---VPYRDSKLTRLLQDSLGGSAHSILIA
:: ::.:.. :: ::..: .:..:: .. : ::::::::::::.:::::. ....::
XP_011 KGERLREGANINRSLLALINVLNALADAKGRKTHVPYRDSKLTRLLKDSLGGNCRTVMIA
280 290 300 310 320 330
350 360 370 380 390 400
pF1KE4 NIAPERRFYLDTVSALNFAARSKEV-INRPFTNESLQPHALGPVKLSQKELLGPPEAKRA
:.: : :: ..:..: :.::. .. . ::. : . . :. : . : :
XP_011 AISPSSLTYEDTYNTLKYADRAKEIRLSLKSNVTSLDCHISQYATICQQ-LQAEVAALRK
340 350 360 370 380 390
410 420 430 440 450 460
pF1KE4 RGPEEEEIGSPEPMAAPASASQKLSPLQKLSSMDPAMLERLLSLDRLLAS-QGSQGAPLL
. : :.: :. :.: .. : . :: : .: :. .. : :
XP_011 KLQVYEGGGQPPPQDLPGSPKSGPPPEHLPSSPLPPHPPSQPCTPELPAGPRALQEESLG
400 410 420 430 440 450
470 480 490 500 510
pF1KE4 STPKRERMVLMKTVEEKDLEIERLKTKQKELEAKMLAQKAEEKENHCPTM-LRP------
. :: . .. .... .. . .:. ..: :. . . : . :.:
XP_011 MEAQVERAMEGNSSDQEQSPEDEDEGPAEEVPTQMPEQNPTHALPESPRLTLQPKPVVGH
460 470 480 490 500 510
520 530 540 550 560 570
pF1KE4 LSHRTVTGAKPLKKAVVMPLQLIQEQAASPNAEIHILKNKGRKRKLESLDALEPEEKAED
.: : . : . :. .. : . :.: . .: : . ..:.:. : ::: :
XP_011 FSARELDGDRS-KQLALKVLCVAQRQYSLLQAAN--LLTPDMITEFETLQQLVQEEKIEP
520 530 540 550 560 570
580 590 600 610 620 630
pF1KE4 CWELQISPELLAHGRQKILDLLNEGSARDLRSLQRIGPKKAQLIVGWRELHGPFSQVEDL
: . ::.: .: .:. . :: . :.: ::.
XP_011 GAE-ALRTSGLARGAPLAQELCSES-----KPPGYTGPVTRTMA---RRLSGPLHTLGIP
580 590 600 610 620
640 650 660
pF1KE4 ERVEGITGKQMESFLKANILGLAAGQRCGAS
XP_011 PGPNCTPAQGSRWPMEKKRRRPSALEADSPMAPKRGTKRQRQSFLPCLRRGSLPDTQPSQ
630 640 650 660 670 680
>>NP_001251503 (OMIM: 614570) kinesin-like protein KIF18 (833 aa)
initn: 525 init1: 220 opt: 720 Z-score: 637.1 bits: 128.5 E(85289): 9.6e-29
Smith-Waterman score: 728; 33.0% identity (58.4% similar) in 534 aa overlap (80-598:62-585)
50 60 70 80 90 100
pF1KE4 LRPFVDGTAGASDPPCVRGMDSCSLEIANWRNHQETLKYQFDAFYGERSTQQDIYAGSVQ
... . : . :: .:: .::::.. ...
NP_001 VVDERVLVFNPEEPDGGFPGLKWGGTHDGPKKKGKDLTFVFDRVFGEAATQQDVFQHTTH
40 50 60 70 80 90
110 120 130 140 150 160
pF1KE4 PILRHLLEGQNASVLAYGPTGAGKTHTMLGSPEQPGVIPRALMDLLQLTREEGAEGRPWA
.: .:.: : ::.::: ::::::::::: .::.. . ..: :. :. .
NP_001 SVLDSFLQGYNCSVFAYGATGAGKTHTMLGREGDPGIM---YLTTVELYRRLEARQQEKH
100 110 120 130 140
170 180 190 200 210 220
pF1KE4 LSVTMSYLEIYQEKVLDLLDPASGDLVIREDCRGNILIPGLS-QKPISSFADFERHFLPA
. : .:: :.:.:.. :::.: .: :.:::: .... ::: ..: :. .: . .
NP_001 FEVLISYQEVYNEQIHDLLEP-KGPLAIREDPDKGVVVQGLSFHQPASAEQLLEI-LTRG
150 160 170 180 190 200
230 240 250 260 270 280
pF1KE4 SRNRTVGATRLNQRSSRSHAVLLVKVDQRERLAPFRQ--REGKLYLIDLAGSEDNRRTGN
.:::: : : ::::::.. . : :..:. . : . .:. :::::::: :
NP_001 NRNRTQHPTDANATSSRSHAIFQIFVKQQDRVPGLTQAVQVAKMSLIDLAGSERASSTHA
210 220 230 240 250 260
290 300 310 320 330 340
pF1KE4 KGLRLKESGAINTSLFVLGKVVDALNQGLPR---VPYRDSKLTRLLQDSLGGSAHSILIA
:: ::.:.. :: ::..: .:..:: .. : ::::::::::::.:::::. ....::
NP_001 KGERLREGANINRSLLALINVLNALADAKGRKTHVPYRDSKLTRLLKDSLGGNCRTVMIA
270 280 290 300 310 320
350 360 370 380 390 400
pF1KE4 NIAPERRFYLDTVSALNFAARSKEV-INRPFTNESLQPHALGPVKLSQKELLGPPEAKRA
:.: : :: ..:..: :.::. .. . ::. : . . :. : . : :
NP_001 AISPSSLTYEDTYNTLKYADRAKEIRLSLKSNVTSLDCHISQYATICQQ-LQAEVAALRK
330 340 350 360 370 380
410 420 430 440 450 460
pF1KE4 RGPEEEEIGSPEPMAAPASASQKLSPLQKLSSMDPAMLERLLSLDRLLAS-QGSQGAPLL
. : :.: :. :.: .. : . :: : .: :. .. : :
NP_001 KLQVYEGGGQPPPQDLPGSPKSGPPPEHLPSSPLPPHPPSQPCTPELPAGPRALQEESLG
390 400 410 420 430 440
470 480 490 500 510
pF1KE4 STPKRERMVLMKTVEEKDLEIERLKTKQKELEAKMLAQKAEEKENHCPTM-LRP------
. :: . .. .... .. . .:. ..: :. . . : . :.:
NP_001 MEAQVERAMEGNSSDQEQSPEDEDEGPAEEVPTQMPEQNPTHALPESPRLTLQPKPVVGH
450 460 470 480 490 500
520 530 540 550 560 570
pF1KE4 LSHRTVTGAKPLKKAVVMPLQLIQEQAASPNAEIHILKNKGRKRKLESLDALEPEEKAED
.: : . : . :. .. : . :.: . .: : . ..:.:. : ::: :
NP_001 FSARELDGDRS-KQLALKVLCVAQRQYSLLQAA--NLLTPDMITEFETLQQLVQEEKIEP
510 520 530 540 550 560
580 590 600 610 620 630
pF1KE4 CWELQISPELLAHGRQKILDLLNEGSARDLRSLQRIGPKKAQLIVGWRELHGPFSQVEDL
: . ::.: .: .:
NP_001 GAE-ALRTSGLARGAPLAQELCSESIPVPSPLCPEPPGYTGPVTRTMARRLSGPLHTLGI
570 580 590 600 610 620
665 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 23:59:39 2016 done: Sat Nov 5 23:59:41 2016
Total Scan time: 11.640 Total Display time: 0.140
Function used was FASTA [36.3.4 Apr, 2011]