Result of FASTA (omim) for
pFN21AE4552
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE4552, 662 aa
1>>>pF1KE4552 662 - 662 aa - 662 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.8070+/-0.000524; mu= 16.9557+/- 0.032
mean_var=85.3803+/-17.734, 0's: 0 Z-trim(108.7): 239 B-trim: 336 in 1/49
Lambda= 0.138802
statistics sampled from 16541 (16821) to 16541 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.546), E-opt: 0.2 (0.197), width: 16
Scan time: 10.730
The best scores are: opt bits E(85289)
NP_058198 (OMIM: 603076) ATP-binding cassette sub- ( 666) 4367 885.5 0
NP_997057 (OMIM: 603076) ATP-binding cassette sub- ( 677) 4311 874.2 0
NP_997512 (OMIM: 603076) ATP-binding cassette sub- ( 663) 4307 873.4 0
NP_997510 (OMIM: 603076) ATP-binding cassette sub- ( 668) 4307 873.4 0
NP_997511 (OMIM: 603076) ATP-binding cassette sub- ( 644) 4261 864.2 0
NP_071452 (OMIM: 607784) ATP-binding cassette sub- ( 646) 3070 625.7 1.6e-178
NP_001135977 (OMIM: 607784) ATP-binding cassette s ( 646) 3070 625.7 1.6e-178
XP_011541254 (OMIM: 607784) PREDICTED: ATP-binding ( 582) 2843 580.2 7e-165
XP_016873610 (OMIM: 607784) PREDICTED: ATP-binding ( 585) 2843 580.2 7.1e-165
NP_004906 (OMIM: 603076) ATP-binding cassette sub- ( 678) 2485 508.6 3e-143
XP_011528109 (OMIM: 603076) PREDICTED: ATP-binding ( 641) 2429 497.4 6.9e-140
XP_011528108 (OMIM: 603076) PREDICTED: ATP-binding ( 689) 2429 497.4 7.3e-140
NP_071881 (OMIM: 210250,605459) ATP-binding casset ( 651) 762 163.6 2.1e-39
XP_006712136 (OMIM: 210250,605459) PREDICTED: ATP- ( 593) 735 158.1 8.4e-38
XP_011531327 (OMIM: 210250,605459) PREDICTED: ATP- ( 570) 723 155.7 4.3e-37
XP_005264537 (OMIM: 210250,605459) PREDICTED: ATP- ( 558) 687 148.5 6.3e-35
NP_001244315 (OMIM: 138900,603756,614490) ATP-bind ( 611) 620 135.1 7.4e-31
XP_016864341 (OMIM: 138900,603756,614490) PREDICTE ( 653) 620 135.1 7.8e-31
XP_005263413 (OMIM: 138900,603756,614490) PREDICTE ( 653) 620 135.1 7.8e-31
XP_005263412 (OMIM: 138900,603756,614490) PREDICTE ( 655) 620 135.1 7.8e-31
XP_005263411 (OMIM: 138900,603756,614490) PREDICTE ( 655) 620 135.1 7.8e-31
NP_004818 (OMIM: 138900,603756,614490) ATP-binding ( 655) 620 135.1 7.8e-31
XP_016864342 (OMIM: 138900,603756,614490) PREDICTE ( 655) 620 135.1 7.8e-31
XP_011530722 (OMIM: 138900,603756,614490) PREDICTE ( 655) 620 135.1 7.8e-31
XP_011531329 (OMIM: 210250,605459) PREDICTED: ATP- ( 480) 583 127.6 1e-28
XP_011531326 (OMIM: 210250,605459) PREDICTED: ATP- ( 606) 553 121.7 8e-27
XP_006712137 (OMIM: 210250,605459) PREDICTED: ATP- ( 339) 525 115.9 2.5e-25
XP_005264540 (OMIM: 210250,605460,611465) PREDICTE ( 672) 511 113.3 3e-24
XP_011531332 (OMIM: 210250,605460,611465) PREDICTE ( 676) 511 113.3 3e-24
NP_071882 (OMIM: 210250,605460,611465) ATP-binding ( 673) 508 112.7 4.5e-24
XP_011531331 (OMIM: 210250,605460,611465) PREDICTE ( 677) 508 112.7 4.5e-24
NP_056472 (OMIM: 242500,601277,607800) ATP-binding (2277) 326 76.6 1.1e-12
NP_775099 (OMIM: 242500,601277,607800) ATP-binding (2595) 326 76.6 1.3e-12
XP_011509253 (OMIM: 242500,601277,607800) PREDICTE (2598) 326 76.6 1.3e-12
XP_011531330 (OMIM: 210250,605459) PREDICTED: ATP- ( 372) 308 72.5 3.2e-12
NP_001080 (OMIM: 601615,610921) ATP-binding casset (1704) 305 72.3 1.6e-11
NP_525021 (OMIM: 612508) ATP-binding cassette sub- (1543) 298 70.9 4e-11
XP_011516646 (OMIM: 143890,205400,600046,604091) P (1565) 297 70.7 4.7e-11
XP_011516644 (OMIM: 143890,205400,600046,604091) P (2142) 297 70.8 6e-11
XP_005251833 (OMIM: 143890,205400,600046,604091) P (2203) 297 70.8 6.1e-11
XP_016869871 (OMIM: 143890,205400,600046,604091) P (2242) 297 70.8 6.2e-11
NP_005493 (OMIM: 143890,205400,600046,604091) ATP- (2261) 297 70.8 6.3e-11
XP_005251830 (OMIM: 143890,205400,600046,604091) P (2263) 297 70.8 6.3e-11
XP_011516643 (OMIM: 143890,205400,600046,604091) P (2286) 297 70.8 6.3e-11
XP_016869869 (OMIM: 143890,205400,600046,604091) P (2288) 297 70.8 6.3e-11
XP_016869870 (OMIM: 143890,205400,600046,604091) P (2288) 297 70.8 6.3e-11
XP_016869867 (OMIM: 143890,205400,600046,604091) P (2288) 297 70.8 6.3e-11
XP_016869868 (OMIM: 143890,205400,600046,604091) P (2288) 297 70.8 6.3e-11
XP_011516642 (OMIM: 143890,205400,600046,604091) P (2288) 297 70.8 6.3e-11
XP_011516641 (OMIM: 143890,205400,600046,604091) P (2288) 297 70.8 6.3e-11
>>NP_058198 (OMIM: 603076) ATP-binding cassette sub-fami (666 aa)
initn: 4367 init1: 4367 opt: 4367 Z-score: 4729.6 bits: 885.5 E(85289): 0
Smith-Waterman score: 4367; 100.0% identity (100.0% similar) in 662 aa overlap (1-662:5-666)
10 20 30 40 50
pF1KE4 MAAFSVGTAMNASSYSAEMTEPKSVCVSVDEVVSSNMEATETDLLNGHLKKVDNNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_058 MACLMAAFSVGTAMNASSYSAEMTEPKSVCVSVDEVVSSNMEATETDLLNGHLKKVDNNL
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE4 TEAQRFSSLPRRAAVNIEFRDLSYSVPEGPWWRKKGYKTLLKGISGKFNSGELVAIMGPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_058 TEAQRFSSLPRRAAVNIEFRDLSYSVPEGPWWRKKGYKTLLKGISGKFNSGELVAIMGPS
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE4 GAGKSTLMNILAGYRETGMKGAVLINGLPRDLRCFRKVSCYIMQDDMLLPHLTVQEAMMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_058 GAGKSTLMNILAGYRETGMKGAVLINGLPRDLRCFRKVSCYIMQDDMLLPHLTVQEAMMV
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE4 SAHLKLQEKDEGRREMVKEILTALGLLSCANTRTGSLSGGQRKRLAIALELVNNPPVMFF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_058 SAHLKLQEKDEGRREMVKEILTALGLLSCANTRTGSLSGGQRKRLAIALELVNNPPVMFF
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE4 DEPTSGLDSASCFQVVSLMKGLAQGGRSIICTIHQPSAKLFELFDQLYVLSQGQCVYRGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_058 DEPTSGLDSASCFQVVSLMKGLAQGGRSIICTIHQPSAKLFELFDQLYVLSQGQCVYRGK
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE4 VCNLVPYLRDLGLNCPTYHNPADFVMEVASGEYGDQNSRLVRAVREGMCDSDHKRDLGGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_058 VCNLVPYLRDLGLNCPTYHNPADFVMEVASGEYGDQNSRLVRAVREGMCDSDHKRDLGGD
310 320 330 340 350 360
360 370 380 390 400 410
pF1KE4 AEVNPFLWHRPSEEDSSSMEGCHSFSASCLTQFCILFKRTFLSIMRDSVLTHLRITSHIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_058 AEVNPFLWHRPSEEDSSSMEGCHSFSASCLTQFCILFKRTFLSIMRDSVLTHLRITSHIG
370 380 390 400 410 420
420 430 440 450 460 470
pF1KE4 IGLLIGLLYLGIGNEAKKVLSNSGFLFFSMLFLMFAALMPTVLTFPLEMGVFLREHLNYW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_058 IGLLIGLLYLGIGNEAKKVLSNSGFLFFSMLFLMFAALMPTVLTFPLEMGVFLREHLNYW
430 440 450 460 470 480
480 490 500 510 520 530
pF1KE4 YSLKAYYLAKTMADVPFQIMFPVAYCSIVYWMTSQPSDAVRFVLFAALGTMTSLVAQSLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_058 YSLKAYYLAKTMADVPFQIMFPVAYCSIVYWMTSQPSDAVRFVLFAALGTMTSLVAQSLG
490 500 510 520 530 540
540 550 560 570 580 590
pF1KE4 LLIGAASTSLQVATFVGPVTAIPVLLFSGFFVSFDTIPTYLQWMSYISYVRYGFEGVILS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_058 LLIGAASTSLQVATFVGPVTAIPVLLFSGFFVSFDTIPTYLQWMSYISYVRYGFEGVILS
550 560 570 580 590 600
600 610 620 630 640 650
pF1KE4 IYGLDREDLHCDIDETCHFQKSEAILRELDVENAKLYLDFIVLGIFFISLRLIAYFVLRY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_058 IYGLDREDLHCDIDETCHFQKSEAILRELDVENAKLYLDFIVLGIFFISLRLIAYFVLRY
610 620 630 640 650 660
660
pF1KE4 KIRAER
::::::
NP_058 KIRAER
>>NP_997057 (OMIM: 603076) ATP-binding cassette sub-fami (677 aa)
initn: 4311 init1: 4311 opt: 4311 Z-score: 4668.9 bits: 874.2 E(85289): 0
Smith-Waterman score: 4311; 99.7% identity (99.8% similar) in 655 aa overlap (8-662:23-677)
10 20 30 40
pF1KE4 MAAFSVGTAMNASSYSAEMTEPKSVCVSVDEVVSSNMEATETDLL
:. :::::::::::::::::::::::::::::::::::
NP_997 MRISLPRAPERDGGVSASSLLDTVTNASSYSAEMTEPKSVCVSVDEVVSSNMEATETDLL
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE4 NGHLKKVDNNLTEAQRFSSLPRRAAVNIEFRDLSYSVPEGPWWRKKGYKTLLKGISGKFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_997 NGHLKKVDNNLTEAQRFSSLPRRAAVNIEFRDLSYSVPEGPWWRKKGYKTLLKGISGKFN
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE4 SGELVAIMGPSGAGKSTLMNILAGYRETGMKGAVLINGLPRDLRCFRKVSCYIMQDDMLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_997 SGELVAIMGPSGAGKSTLMNILAGYRETGMKGAVLINGLPRDLRCFRKVSCYIMQDDMLL
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE4 PHLTVQEAMMVSAHLKLQEKDEGRREMVKEILTALGLLSCANTRTGSLSGGQRKRLAIAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_997 PHLTVQEAMMVSAHLKLQEKDEGRREMVKEILTALGLLSCANTRTGSLSGGQRKRLAIAL
190 200 210 220 230 240
230 240 250 260 270 280
pF1KE4 ELVNNPPVMFFDEPTSGLDSASCFQVVSLMKGLAQGGRSIICTIHQPSAKLFELFDQLYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_997 ELVNNPPVMFFDEPTSGLDSASCFQVVSLMKGLAQGGRSIICTIHQPSAKLFELFDQLYV
250 260 270 280 290 300
290 300 310 320 330 340
pF1KE4 LSQGQCVYRGKVCNLVPYLRDLGLNCPTYHNPADFVMEVASGEYGDQNSRLVRAVREGMC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_997 LSQGQCVYRGKVCNLVPYLRDLGLNCPTYHNPADFVMEVASGEYGDQNSRLVRAVREGMC
310 320 330 340 350 360
350 360 370 380 390 400
pF1KE4 DSDHKRDLGGDAEVNPFLWHRPSEEDSSSMEGCHSFSASCLTQFCILFKRTFLSIMRDSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_997 DSDHKRDLGGDAEVNPFLWHRPSEEDSSSMEGCHSFSASCLTQFCILFKRTFLSIMRDSV
370 380 390 400 410 420
410 420 430 440 450 460
pF1KE4 LTHLRITSHIGIGLLIGLLYLGIGNEAKKVLSNSGFLFFSMLFLMFAALMPTVLTFPLEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_997 LTHLRITSHIGIGLLIGLLYLGIGNEAKKVLSNSGFLFFSMLFLMFAALMPTVLTFPLEM
430 440 450 460 470 480
470 480 490 500 510 520
pF1KE4 GVFLREHLNYWYSLKAYYLAKTMADVPFQIMFPVAYCSIVYWMTSQPSDAVRFVLFAALG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_997 GVFLREHLNYWYSLKAYYLAKTMADVPFQIMFPVAYCSIVYWMTSQPSDAVRFVLFAALG
490 500 510 520 530 540
530 540 550 560 570 580
pF1KE4 TMTSLVAQSLGLLIGAASTSLQVATFVGPVTAIPVLLFSGFFVSFDTIPTYLQWMSYISY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_997 TMTSLVAQSLGLLIGAASTSLQVATFVGPVTAIPVLLFSGFFVSFDTIPTYLQWMSYISY
550 560 570 580 590 600
590 600 610 620 630 640
pF1KE4 VRYGFEGVILSIYGLDREDLHCDIDETCHFQKSEAILRELDVENAKLYLDFIVLGIFFIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_997 VRYGFEGVILSIYGLDREDLHCDIDETCHFQKSEAILRELDVENAKLYLDFIVLGIFFIS
610 620 630 640 650 660
650 660
pF1KE4 LRLIAYFVLRYKIRAER
:::::::::::::::::
NP_997 LRLIAYFVLRYKIRAER
670
>>NP_997512 (OMIM: 603076) ATP-binding cassette sub-fami (663 aa)
initn: 4307 init1: 4307 opt: 4307 Z-score: 4664.7 bits: 873.4 E(85289): 0
Smith-Waterman score: 4307; 100.0% identity (100.0% similar) in 652 aa overlap (11-662:12-663)
10 20 30 40 50
pF1KE4 MAAFSVGTAMNASSYSAEMTEPKSVCVSVDEVVSSNMEATETDLLNGHLKKVDNNLTEA
:::::::::::::::::::::::::::::::::::::::::::::::::
NP_997 MIMRLPQPHGTNASSYSAEMTEPKSVCVSVDEVVSSNMEATETDLLNGHLKKVDNNLTEA
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE4 QRFSSLPRRAAVNIEFRDLSYSVPEGPWWRKKGYKTLLKGISGKFNSGELVAIMGPSGAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_997 QRFSSLPRRAAVNIEFRDLSYSVPEGPWWRKKGYKTLLKGISGKFNSGELVAIMGPSGAG
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE4 KSTLMNILAGYRETGMKGAVLINGLPRDLRCFRKVSCYIMQDDMLLPHLTVQEAMMVSAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_997 KSTLMNILAGYRETGMKGAVLINGLPRDLRCFRKVSCYIMQDDMLLPHLTVQEAMMVSAH
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE4 LKLQEKDEGRREMVKEILTALGLLSCANTRTGSLSGGQRKRLAIALELVNNPPVMFFDEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_997 LKLQEKDEGRREMVKEILTALGLLSCANTRTGSLSGGQRKRLAIALELVNNPPVMFFDEP
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE4 TSGLDSASCFQVVSLMKGLAQGGRSIICTIHQPSAKLFELFDQLYVLSQGQCVYRGKVCN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_997 TSGLDSASCFQVVSLMKGLAQGGRSIICTIHQPSAKLFELFDQLYVLSQGQCVYRGKVCN
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE4 LVPYLRDLGLNCPTYHNPADFVMEVASGEYGDQNSRLVRAVREGMCDSDHKRDLGGDAEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_997 LVPYLRDLGLNCPTYHNPADFVMEVASGEYGDQNSRLVRAVREGMCDSDHKRDLGGDAEV
310 320 330 340 350 360
360 370 380 390 400 410
pF1KE4 NPFLWHRPSEEDSSSMEGCHSFSASCLTQFCILFKRTFLSIMRDSVLTHLRITSHIGIGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_997 NPFLWHRPSEEDSSSMEGCHSFSASCLTQFCILFKRTFLSIMRDSVLTHLRITSHIGIGL
370 380 390 400 410 420
420 430 440 450 460 470
pF1KE4 LIGLLYLGIGNEAKKVLSNSGFLFFSMLFLMFAALMPTVLTFPLEMGVFLREHLNYWYSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_997 LIGLLYLGIGNEAKKVLSNSGFLFFSMLFLMFAALMPTVLTFPLEMGVFLREHLNYWYSL
430 440 450 460 470 480
480 490 500 510 520 530
pF1KE4 KAYYLAKTMADVPFQIMFPVAYCSIVYWMTSQPSDAVRFVLFAALGTMTSLVAQSLGLLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_997 KAYYLAKTMADVPFQIMFPVAYCSIVYWMTSQPSDAVRFVLFAALGTMTSLVAQSLGLLI
490 500 510 520 530 540
540 550 560 570 580 590
pF1KE4 GAASTSLQVATFVGPVTAIPVLLFSGFFVSFDTIPTYLQWMSYISYVRYGFEGVILSIYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_997 GAASTSLQVATFVGPVTAIPVLLFSGFFVSFDTIPTYLQWMSYISYVRYGFEGVILSIYG
550 560 570 580 590 600
600 610 620 630 640 650
pF1KE4 LDREDLHCDIDETCHFQKSEAILRELDVENAKLYLDFIVLGIFFISLRLIAYFVLRYKIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_997 LDREDLHCDIDETCHFQKSEAILRELDVENAKLYLDFIVLGIFFISLRLIAYFVLRYKIR
610 620 630 640 650 660
660
pF1KE4 AER
:::
NP_997 AER
>>NP_997510 (OMIM: 603076) ATP-binding cassette sub-fami (668 aa)
initn: 4307 init1: 4307 opt: 4307 Z-score: 4664.6 bits: 873.4 E(85289): 0
Smith-Waterman score: 4307; 100.0% identity (100.0% similar) in 652 aa overlap (11-662:17-668)
10 20 30 40 50
pF1KE4 MAAFSVGTAMNASSYSAEMTEPKSVCVSVDEVVSSNMEATETDLLNGHLKKVDN
::::::::::::::::::::::::::::::::::::::::::::
NP_997 MLGTQGWTKQRKPCPQNASSYSAEMTEPKSVCVSVDEVVSSNMEATETDLLNGHLKKVDN
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE4 NLTEAQRFSSLPRRAAVNIEFRDLSYSVPEGPWWRKKGYKTLLKGISGKFNSGELVAIMG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_997 NLTEAQRFSSLPRRAAVNIEFRDLSYSVPEGPWWRKKGYKTLLKGISGKFNSGELVAIMG
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE4 PSGAGKSTLMNILAGYRETGMKGAVLINGLPRDLRCFRKVSCYIMQDDMLLPHLTVQEAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_997 PSGAGKSTLMNILAGYRETGMKGAVLINGLPRDLRCFRKVSCYIMQDDMLLPHLTVQEAM
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE4 MVSAHLKLQEKDEGRREMVKEILTALGLLSCANTRTGSLSGGQRKRLAIALELVNNPPVM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_997 MVSAHLKLQEKDEGRREMVKEILTALGLLSCANTRTGSLSGGQRKRLAIALELVNNPPVM
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE4 FFDEPTSGLDSASCFQVVSLMKGLAQGGRSIICTIHQPSAKLFELFDQLYVLSQGQCVYR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_997 FFDEPTSGLDSASCFQVVSLMKGLAQGGRSIICTIHQPSAKLFELFDQLYVLSQGQCVYR
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE4 GKVCNLVPYLRDLGLNCPTYHNPADFVMEVASGEYGDQNSRLVRAVREGMCDSDHKRDLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_997 GKVCNLVPYLRDLGLNCPTYHNPADFVMEVASGEYGDQNSRLVRAVREGMCDSDHKRDLG
310 320 330 340 350 360
360 370 380 390 400 410
pF1KE4 GDAEVNPFLWHRPSEEDSSSMEGCHSFSASCLTQFCILFKRTFLSIMRDSVLTHLRITSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_997 GDAEVNPFLWHRPSEEDSSSMEGCHSFSASCLTQFCILFKRTFLSIMRDSVLTHLRITSH
370 380 390 400 410 420
420 430 440 450 460 470
pF1KE4 IGIGLLIGLLYLGIGNEAKKVLSNSGFLFFSMLFLMFAALMPTVLTFPLEMGVFLREHLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_997 IGIGLLIGLLYLGIGNEAKKVLSNSGFLFFSMLFLMFAALMPTVLTFPLEMGVFLREHLN
430 440 450 460 470 480
480 490 500 510 520 530
pF1KE4 YWYSLKAYYLAKTMADVPFQIMFPVAYCSIVYWMTSQPSDAVRFVLFAALGTMTSLVAQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_997 YWYSLKAYYLAKTMADVPFQIMFPVAYCSIVYWMTSQPSDAVRFVLFAALGTMTSLVAQS
490 500 510 520 530 540
540 550 560 570 580 590
pF1KE4 LGLLIGAASTSLQVATFVGPVTAIPVLLFSGFFVSFDTIPTYLQWMSYISYVRYGFEGVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_997 LGLLIGAASTSLQVATFVGPVTAIPVLLFSGFFVSFDTIPTYLQWMSYISYVRYGFEGVI
550 560 570 580 590 600
600 610 620 630 640 650
pF1KE4 LSIYGLDREDLHCDIDETCHFQKSEAILRELDVENAKLYLDFIVLGIFFISLRLIAYFVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_997 LSIYGLDREDLHCDIDETCHFQKSEAILRELDVENAKLYLDFIVLGIFFISLRLIAYFVL
610 620 630 640 650 660
660
pF1KE4 RYKIRAER
::::::::
NP_997 RYKIRAER
>>NP_997511 (OMIM: 603076) ATP-binding cassette sub-fami (644 aa)
initn: 4261 init1: 4261 opt: 4261 Z-score: 4615.1 bits: 864.2 E(85289): 0
Smith-Waterman score: 4261; 100.0% identity (100.0% similar) in 644 aa overlap (19-662:1-644)
10 20 30 40 50 60
pF1KE4 MAAFSVGTAMNASSYSAEMTEPKSVCVSVDEVVSSNMEATETDLLNGHLKKVDNNLTEAQ
::::::::::::::::::::::::::::::::::::::::::
NP_997 MTEPKSVCVSVDEVVSSNMEATETDLLNGHLKKVDNNLTEAQ
10 20 30 40
70 80 90 100 110 120
pF1KE4 RFSSLPRRAAVNIEFRDLSYSVPEGPWWRKKGYKTLLKGISGKFNSGELVAIMGPSGAGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_997 RFSSLPRRAAVNIEFRDLSYSVPEGPWWRKKGYKTLLKGISGKFNSGELVAIMGPSGAGK
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE4 STLMNILAGYRETGMKGAVLINGLPRDLRCFRKVSCYIMQDDMLLPHLTVQEAMMVSAHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_997 STLMNILAGYRETGMKGAVLINGLPRDLRCFRKVSCYIMQDDMLLPHLTVQEAMMVSAHL
110 120 130 140 150 160
190 200 210 220 230 240
pF1KE4 KLQEKDEGRREMVKEILTALGLLSCANTRTGSLSGGQRKRLAIALELVNNPPVMFFDEPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_997 KLQEKDEGRREMVKEILTALGLLSCANTRTGSLSGGQRKRLAIALELVNNPPVMFFDEPT
170 180 190 200 210 220
250 260 270 280 290 300
pF1KE4 SGLDSASCFQVVSLMKGLAQGGRSIICTIHQPSAKLFELFDQLYVLSQGQCVYRGKVCNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_997 SGLDSASCFQVVSLMKGLAQGGRSIICTIHQPSAKLFELFDQLYVLSQGQCVYRGKVCNL
230 240 250 260 270 280
310 320 330 340 350 360
pF1KE4 VPYLRDLGLNCPTYHNPADFVMEVASGEYGDQNSRLVRAVREGMCDSDHKRDLGGDAEVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_997 VPYLRDLGLNCPTYHNPADFVMEVASGEYGDQNSRLVRAVREGMCDSDHKRDLGGDAEVN
290 300 310 320 330 340
370 380 390 400 410 420
pF1KE4 PFLWHRPSEEDSSSMEGCHSFSASCLTQFCILFKRTFLSIMRDSVLTHLRITSHIGIGLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_997 PFLWHRPSEEDSSSMEGCHSFSASCLTQFCILFKRTFLSIMRDSVLTHLRITSHIGIGLL
350 360 370 380 390 400
430 440 450 460 470 480
pF1KE4 IGLLYLGIGNEAKKVLSNSGFLFFSMLFLMFAALMPTVLTFPLEMGVFLREHLNYWYSLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_997 IGLLYLGIGNEAKKVLSNSGFLFFSMLFLMFAALMPTVLTFPLEMGVFLREHLNYWYSLK
410 420 430 440 450 460
490 500 510 520 530 540
pF1KE4 AYYLAKTMADVPFQIMFPVAYCSIVYWMTSQPSDAVRFVLFAALGTMTSLVAQSLGLLIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_997 AYYLAKTMADVPFQIMFPVAYCSIVYWMTSQPSDAVRFVLFAALGTMTSLVAQSLGLLIG
470 480 490 500 510 520
550 560 570 580 590 600
pF1KE4 AASTSLQVATFVGPVTAIPVLLFSGFFVSFDTIPTYLQWMSYISYVRYGFEGVILSIYGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_997 AASTSLQVATFVGPVTAIPVLLFSGFFVSFDTIPTYLQWMSYISYVRYGFEGVILSIYGL
530 540 550 560 570 580
610 620 630 640 650 660
pF1KE4 DREDLHCDIDETCHFQKSEAILRELDVENAKLYLDFIVLGIFFISLRLIAYFVLRYKIRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_997 DREDLHCDIDETCHFQKSEAILRELDVENAKLYLDFIVLGIFFISLRLIAYFVLRYKIRA
590 600 610 620 630 640
pF1KE4 ER
::
NP_997 ER
>>NP_071452 (OMIM: 607784) ATP-binding cassette sub-fami (646 aa)
initn: 3048 init1: 1614 opt: 3070 Z-score: 3326.1 bits: 625.7 E(85289): 1.6e-178
Smith-Waterman score: 3070; 73.6% identity (89.9% similar) in 625 aa overlap (38-662:26-646)
10 20 30 40 50 60
pF1KE4 TAMNASSYSAEMTEPKSVCVSVDEVVSSNMEATETDLLNGHLKKVDNNLTEAQRFSSLPR
...: .:. :::::.:..::::::: ::.
NP_071 MAEKALEAVGCGLGPGAVAMAVTLEDGAEPPVLTTHLKKVENHITEAQRFSHLPK
10 20 30 40 50
70 80 90 100 110 120
pF1KE4 RAAVNIEFRDLSYSVPEGPWWRKKGYKTLLKGISGKFNSGELVAIMGPSGAGKSTLMNIL
:.::.::: .::::: ::: :::.::::::: .:::: ::..:::::::::::.::::
NP_071 RSAVDIEFVELSYSVREGPCWRKRGYKTLLKCLSGKFCRRELIGIMGPSGAGKSTFMNIL
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE4 AGYRETGMKGAVLINGLPRDLRCFRKVSCYIMQDDMLLPHLTVQEAMMVSAHLKLQEKDE
:::::.:::: .:.:: ::.:: :::.:::::::::::::::: :::::::.:::.::.:
NP_071 AGYRESGMKGQILVNGRPRELRTFRKMSCYIMQDDMLLPHLTVLEAMMVSANLKLSEKQE
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE4 GRREMVKEILTALGLLSCANTRTGSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSAS
..:.: ::::::::.::..:::. :::::::::::::::::::::::::::::::::::
NP_071 VKKELVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSAS
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE4 CFQVVSLMKGLAQGGRSIICTIHQPSAKLFELFDQLYVLSQGQCVYRGKVCNLVPYLRDL
:::::::::.::::::.::::::::::::::.::.::.::::::...: : ::.:::. :
NP_071 CFQVVSLMKSLAQGGRTIICTIHQPSAKLFEMFDKLYILSQGQCIFKGVVTNLIPYLKGL
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE4 GLNCPTYHNPADFVMEVASGEYGDQNSRLVRAVREGMCDSDHKRDLGGDAEVNPFLWHRP
::.::::::::::..::::::::: : : :::..:.: .:.. :: :
NP_071 GLHCPTYHNPADFIIEVASGEYGDLNPMLFRAVQNGLCAMAEKKSSPEKNEVPAPCPPCP
300 310 320 330 340 350
370 380 390 400 410 420
pF1KE4 SEEDSSSMEGCHSFSASCLTQFCILFKRTFLSIMRDSVLTHLRITSHIGIGLLIGLLYLG
: : .:. :.:..: :::::::::::::::.::.::::::. ::. ::.:::::::
NP_071 PEVD--PIES-HTFATSTLTQFCILFKRTFLSILRDTVLTHLRFMSHVVIGVLIGLLYLH
360 370 380 390 400 410
430 440 450 460 470 480
pF1KE4 IGNEAKKVLSNSGFLFFSMLFLMFAALMPTVLTFPLEMGVFLREHLNYWYSLKAYYLAKT
::..:.::..:.: ::::::::::::::::::::::::.::.::::::::::::::::::
NP_071 IGDDASKVFNNTGCLFFSMLFLMFAALMPTVLTFPLEMAVFMREHLNYWYSLKAYYLAKT
420 430 440 450 460 470
490 500 510 520 530 540
pF1KE4 MADVPFQIMFPVAYCSIVYWMTSQPSDAVRFVLFAALGTMTSLVAQSLGLLIGAASTSLQ
:::::::.. ::.:::::::::.::... ::.::.::.: :.::::::::::::::.:::
NP_071 MADVPFQVVCPVVYCSIVYWMTGQPAETSRFLLFSALATATALVAQSLGLLIGAASNSLQ
480 490 500 510 520 530
550 560 570 580 590 600
pF1KE4 VATFVGPVTAIPVLLFSGFFVSFDTIPTYLQWMSYISYVRYGFEGVILSIYGLDREDLHC
::::::::::::::::::::::: :::::::: ::.::::::::::::.:::..: :: :
NP_071 VATFVGPVTAIPVLLFSGFFVSFKTIPTYLQWSSYLSYVRYGFEGVILTIYGMERGDLTC
540 550 560 570 580 590
610 620 630 640 650 660
pF1KE4 DIDETCHFQKSEAILRELDVENAKLYLDFIVLGIFFISLRLIAYFVLRYKIRAER
..: : :.. ..::: ::::.::::.::.::::::..:::.::.::::....::
NP_071 -LEERCPFREPQSILRALDVEDAKLYMDFLVLGIFFLALRLLAYLVLRYRVKSER
600 610 620 630 640
>>NP_001135977 (OMIM: 607784) ATP-binding cassette sub-f (646 aa)
initn: 3048 init1: 1614 opt: 3070 Z-score: 3326.1 bits: 625.7 E(85289): 1.6e-178
Smith-Waterman score: 3070; 73.6% identity (89.9% similar) in 625 aa overlap (38-662:26-646)
10 20 30 40 50 60
pF1KE4 TAMNASSYSAEMTEPKSVCVSVDEVVSSNMEATETDLLNGHLKKVDNNLTEAQRFSSLPR
...: .:. :::::.:..::::::: ::.
NP_001 MAEKALEAVGCGLGPGAVAMAVTLEDGAEPPVLTTHLKKVENHITEAQRFSHLPK
10 20 30 40 50
70 80 90 100 110 120
pF1KE4 RAAVNIEFRDLSYSVPEGPWWRKKGYKTLLKGISGKFNSGELVAIMGPSGAGKSTLMNIL
:.::.::: .::::: ::: :::.::::::: .:::: ::..:::::::::::.::::
NP_001 RSAVDIEFVELSYSVREGPCWRKRGYKTLLKCLSGKFCRRELIGIMGPSGAGKSTFMNIL
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE4 AGYRETGMKGAVLINGLPRDLRCFRKVSCYIMQDDMLLPHLTVQEAMMVSAHLKLQEKDE
:::::.:::: .:.:: ::.:: :::.:::::::::::::::: :::::::.:::.::.:
NP_001 AGYRESGMKGQILVNGRPRELRTFRKMSCYIMQDDMLLPHLTVLEAMMVSANLKLSEKQE
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE4 GRREMVKEILTALGLLSCANTRTGSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSAS
..:.: ::::::::.::..:::. :::::::::::::::::::::::::::::::::::
NP_001 VKKELVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSAS
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE4 CFQVVSLMKGLAQGGRSIICTIHQPSAKLFELFDQLYVLSQGQCVYRGKVCNLVPYLRDL
:::::::::.::::::.::::::::::::::.::.::.::::::...: : ::.:::. :
NP_001 CFQVVSLMKSLAQGGRTIICTIHQPSAKLFEMFDKLYILSQGQCIFKGVVTNLIPYLKGL
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE4 GLNCPTYHNPADFVMEVASGEYGDQNSRLVRAVREGMCDSDHKRDLGGDAEVNPFLWHRP
::.::::::::::..::::::::: : : :::..:.: .:.. :: :
NP_001 GLHCPTYHNPADFIIEVASGEYGDLNPMLFRAVQNGLCAMAEKKSSPEKNEVPAPCPPCP
300 310 320 330 340 350
370 380 390 400 410 420
pF1KE4 SEEDSSSMEGCHSFSASCLTQFCILFKRTFLSIMRDSVLTHLRITSHIGIGLLIGLLYLG
: : .:. :.:..: :::::::::::::::.::.::::::. ::. ::.:::::::
NP_001 PEVD--PIES-HTFATSTLTQFCILFKRTFLSILRDTVLTHLRFMSHVVIGVLIGLLYLH
360 370 380 390 400 410
430 440 450 460 470 480
pF1KE4 IGNEAKKVLSNSGFLFFSMLFLMFAALMPTVLTFPLEMGVFLREHLNYWYSLKAYYLAKT
::..:.::..:.: ::::::::::::::::::::::::.::.::::::::::::::::::
NP_001 IGDDASKVFNNTGCLFFSMLFLMFAALMPTVLTFPLEMAVFMREHLNYWYSLKAYYLAKT
420 430 440 450 460 470
490 500 510 520 530 540
pF1KE4 MADVPFQIMFPVAYCSIVYWMTSQPSDAVRFVLFAALGTMTSLVAQSLGLLIGAASTSLQ
:::::::.. ::.:::::::::.::... ::.::.::.: :.::::::::::::::.:::
NP_001 MADVPFQVVCPVVYCSIVYWMTGQPAETSRFLLFSALATATALVAQSLGLLIGAASNSLQ
480 490 500 510 520 530
550 560 570 580 590 600
pF1KE4 VATFVGPVTAIPVLLFSGFFVSFDTIPTYLQWMSYISYVRYGFEGVILSIYGLDREDLHC
::::::::::::::::::::::: :::::::: ::.::::::::::::.:::..: :: :
NP_001 VATFVGPVTAIPVLLFSGFFVSFKTIPTYLQWSSYLSYVRYGFEGVILTIYGMERGDLTC
540 550 560 570 580 590
610 620 630 640 650 660
pF1KE4 DIDETCHFQKSEAILRELDVENAKLYLDFIVLGIFFISLRLIAYFVLRYKIRAER
..: : :.. ..::: ::::.::::.::.::::::..:::.::.::::....::
NP_001 -LEERCPFREPQSILRALDVEDAKLYMDFLVLGIFFLALRLLAYLVLRYRVKSER
600 610 620 630 640
>>XP_011541254 (OMIM: 607784) PREDICTED: ATP-binding cas (582 aa)
initn: 2821 init1: 1387 opt: 2843 Z-score: 3081.1 bits: 580.2 E(85289): 7e-165
Smith-Waterman score: 2843; 74.6% identity (90.2% similar) in 571 aa overlap (92-662:16-582)
70 80 90 100 110 120
pF1KE4 FSSLPRRAAVNIEFRDLSYSVPEGPWWRKKGYKTLLKGISGKFNSGELVAIMGPSGAGKS
::::::: .:::: ::..::::::::::
XP_011 MCGFSHAFQKRIVASGYKTLLKCLSGKFCRRELIGIMGPSGAGKS
10 20 30 40
130 140 150 160 170 180
pF1KE4 TLMNILAGYRETGMKGAVLINGLPRDLRCFRKVSCYIMQDDMLLPHLTVQEAMMVSAHLK
:.:::::::::.:::: .:.:: ::.:: :::.:::::::::::::::: :::::::.::
XP_011 TFMNILAGYRESGMKGQILVNGRPRELRTFRKMSCYIMQDDMLLPHLTVLEAMMVSANLK
50 60 70 80 90 100
190 200 210 220 230 240
pF1KE4 LQEKDEGRREMVKEILTALGLLSCANTRTGSLSGGQRKRLAIALELVNNPPVMFFDEPTS
:.::.: ..:.: ::::::::.::..:::. :::::::::::::::::::::::::::::
XP_011 LSEKQEVKKELVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTS
110 120 130 140 150 160
250 260 270 280 290 300
pF1KE4 GLDSASCFQVVSLMKGLAQGGRSIICTIHQPSAKLFELFDQLYVLSQGQCVYRGKVCNLV
:::::::::::::::.::::::.::::::::::::::.::.::.::::::...: : ::.
XP_011 GLDSASCFQVVSLMKSLAQGGRTIICTIHQPSAKLFEMFDKLYILSQGQCIFKGVVTNLI
170 180 190 200 210 220
310 320 330 340 350 360
pF1KE4 PYLRDLGLNCPTYHNPADFVMEVASGEYGDQNSRLVRAVREGMCDSDHKRDLGGDAEVNP
:::. :::.::::::::::..::::::::: : : :::..:.: .:.. ::
XP_011 PYLKGLGLHCPTYHNPADFIIEVASGEYGDLNPMLFRAVQNGLCAMAEKKSSPEKNEVPA
230 240 250 260 270 280
370 380 390 400 410 420
pF1KE4 FLWHRPSEEDSSSMEGCHSFSASCLTQFCILFKRTFLSIMRDSVLTHLRITSHIGIGLLI
: : : .:. :.:..: :::::::::::::::.::.::::::. ::. ::.::
XP_011 PCPPCPPEVD--PIES-HTFATSTLTQFCILFKRTFLSILRDTVLTHLRFMSHVVIGVLI
290 300 310 320 330 340
430 440 450 460 470 480
pF1KE4 GLLYLGIGNEAKKVLSNSGFLFFSMLFLMFAALMPTVLTFPLEMGVFLREHLNYWYSLKA
::::: ::..:.::..:.: ::::::::::::::::::::::::.::.::::::::::::
XP_011 GLLYLHIGDDASKVFNNTGCLFFSMLFLMFAALMPTVLTFPLEMAVFMREHLNYWYSLKA
350 360 370 380 390 400
490 500 510 520 530 540
pF1KE4 YYLAKTMADVPFQIMFPVAYCSIVYWMTSQPSDAVRFVLFAALGTMTSLVAQSLGLLIGA
:::::::::::::.. ::.:::::::::.::... ::.::.::.: :.::::::::::::
XP_011 YYLAKTMADVPFQVVCPVVYCSIVYWMTGQPAETSRFLLFSALATATALVAQSLGLLIGA
410 420 430 440 450 460
550 560 570 580 590 600
pF1KE4 ASTSLQVATFVGPVTAIPVLLFSGFFVSFDTIPTYLQWMSYISYVRYGFEGVILSIYGLD
::.:::::::::::::::::::::::::: :::::::: ::.::::::::::::.:::..
XP_011 ASNSLQVATFVGPVTAIPVLLFSGFFVSFKTIPTYLQWSSYLSYVRYGFEGVILTIYGME
470 480 490 500 510 520
610 620 630 640 650 660
pF1KE4 REDLHCDIDETCHFQKSEAILRELDVENAKLYLDFIVLGIFFISLRLIAYFVLRYKIRAE
: :: : ..: : :.. ..::: ::::.::::.::.::::::..:::.::.::::....:
XP_011 RGDLTC-LEERCPFREPQSILRALDVEDAKLYMDFLVLGIFFLALRLLAYLVLRYRVKSE
530 540 550 560 570 580
pF1KE4 R
:
XP_011 R
>>XP_016873610 (OMIM: 607784) PREDICTED: ATP-binding cas (585 aa)
initn: 2821 init1: 1387 opt: 2843 Z-score: 3081.1 bits: 580.2 E(85289): 7.1e-165
Smith-Waterman score: 2843; 74.6% identity (90.2% similar) in 571 aa overlap (92-662:19-585)
70 80 90 100 110 120
pF1KE4 FSSLPRRAAVNIEFRDLSYSVPEGPWWRKKGYKTLLKGISGKFNSGELVAIMGPSGAGKS
::::::: .:::: ::..::::::::::
XP_016 MRDLELREVKQLARGHTAGYKTLLKCLSGKFCRRELIGIMGPSGAGKS
10 20 30 40
130 140 150 160 170 180
pF1KE4 TLMNILAGYRETGMKGAVLINGLPRDLRCFRKVSCYIMQDDMLLPHLTVQEAMMVSAHLK
:.:::::::::.:::: .:.:: ::.:: :::.:::::::::::::::: :::::::.::
XP_016 TFMNILAGYRESGMKGQILVNGRPRELRTFRKMSCYIMQDDMLLPHLTVLEAMMVSANLK
50 60 70 80 90 100
190 200 210 220 230 240
pF1KE4 LQEKDEGRREMVKEILTALGLLSCANTRTGSLSGGQRKRLAIALELVNNPPVMFFDEPTS
:.::.: ..:.: ::::::::.::..:::. :::::::::::::::::::::::::::::
XP_016 LSEKQEVKKELVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTS
110 120 130 140 150 160
250 260 270 280 290 300
pF1KE4 GLDSASCFQVVSLMKGLAQGGRSIICTIHQPSAKLFELFDQLYVLSQGQCVYRGKVCNLV
:::::::::::::::.::::::.::::::::::::::.::.::.::::::...: : ::.
XP_016 GLDSASCFQVVSLMKSLAQGGRTIICTIHQPSAKLFEMFDKLYILSQGQCIFKGVVTNLI
170 180 190 200 210 220
310 320 330 340 350 360
pF1KE4 PYLRDLGLNCPTYHNPADFVMEVASGEYGDQNSRLVRAVREGMCDSDHKRDLGGDAEVNP
:::. :::.::::::::::..::::::::: : : :::..:.: .:.. ::
XP_016 PYLKGLGLHCPTYHNPADFIIEVASGEYGDLNPMLFRAVQNGLCAMAEKKSSPEKNEVPA
230 240 250 260 270 280
370 380 390 400 410 420
pF1KE4 FLWHRPSEEDSSSMEGCHSFSASCLTQFCILFKRTFLSIMRDSVLTHLRITSHIGIGLLI
: : : .:. :.:..: :::::::::::::::.::.::::::. ::. ::.::
XP_016 PCPPCPPEVD--PIES-HTFATSTLTQFCILFKRTFLSILRDTVLTHLRFMSHVVIGVLI
290 300 310 320 330 340
430 440 450 460 470 480
pF1KE4 GLLYLGIGNEAKKVLSNSGFLFFSMLFLMFAALMPTVLTFPLEMGVFLREHLNYWYSLKA
::::: ::..:.::..:.: ::::::::::::::::::::::::.::.::::::::::::
XP_016 GLLYLHIGDDASKVFNNTGCLFFSMLFLMFAALMPTVLTFPLEMAVFMREHLNYWYSLKA
350 360 370 380 390 400
490 500 510 520 530 540
pF1KE4 YYLAKTMADVPFQIMFPVAYCSIVYWMTSQPSDAVRFVLFAALGTMTSLVAQSLGLLIGA
:::::::::::::.. ::.:::::::::.::... ::.::.::.: :.::::::::::::
XP_016 YYLAKTMADVPFQVVCPVVYCSIVYWMTGQPAETSRFLLFSALATATALVAQSLGLLIGA
410 420 430 440 450 460
550 560 570 580 590 600
pF1KE4 ASTSLQVATFVGPVTAIPVLLFSGFFVSFDTIPTYLQWMSYISYVRYGFEGVILSIYGLD
::.:::::::::::::::::::::::::: :::::::: ::.::::::::::::.:::..
XP_016 ASNSLQVATFVGPVTAIPVLLFSGFFVSFKTIPTYLQWSSYLSYVRYGFEGVILTIYGME
470 480 490 500 510 520
610 620 630 640 650 660
pF1KE4 REDLHCDIDETCHFQKSEAILRELDVENAKLYLDFIVLGIFFISLRLIAYFVLRYKIRAE
: :: : ..: : :.. ..::: ::::.::::.::.::::::..:::.::.::::....:
XP_016 RGDLTC-LEERCPFREPQSILRALDVEDAKLYMDFLVLGIFFLALRLLAYLVLRYRVKSE
530 540 550 560 570 580
pF1KE4 R
:
XP_016 R
>>NP_004906 (OMIM: 603076) ATP-binding cassette sub-fami (678 aa)
initn: 2465 init1: 2465 opt: 2485 Z-score: 2692.7 bits: 508.6 E(85289): 3e-143
Smith-Waterman score: 4333; 98.2% identity (98.2% similar) in 674 aa overlap (1-662:5-678)
10 20 30 40 50
pF1KE4 MAAFSVGTAMNASSYSAEMTEPKSVCVSVDEVVSSNMEATETDLLNGHLKKVDNNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MACLMAAFSVGTAMNASSYSAEMTEPKSVCVSVDEVVSSNMEATETDLLNGHLKKVDNNL
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE4 TEAQRFSSLPRRAAVNIEFRDLSYSVPEGPWWRKKGYKTLLKGISGKFNSGELVAIMGPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 TEAQRFSSLPRRAAVNIEFRDLSYSVPEGPWWRKKGYKTLLKGISGKFNSGELVAIMGPS
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE4 GAGKSTLMNILAGYRETGMKGAVLINGLPRDLRCFRKVSCYIMQDDMLLPHLTVQEAMMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 GAGKSTLMNILAGYRETGMKGAVLINGLPRDLRCFRKVSCYIMQDDMLLPHLTVQEAMMV
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE4 SAHLKLQEKDEGRREMVKEILTALGLLSCANTRTGSLSGGQRKRLAIALELVNNPPVMFF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 SAHLKLQEKDEGRREMVKEILTALGLLSCANTRTGSLSGGQRKRLAIALELVNNPPVMFF
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE4 DEPTSGLDSASCFQVVSLMKGLAQGGRSIICTIHQPSAKLFELFDQLYVLSQGQCVYRGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 DEPTSGLDSASCFQVVSLMKGLAQGGRSIICTIHQPSAKLFELFDQLYVLSQGQCVYRGK
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE4 VCNLVPYLRDLGLNCPTYHNPADFVMEVASGEYGDQNSRLVRAVREGMCDSDHKRDLGGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 VCNLVPYLRDLGLNCPTYHNPADFVMEVASGEYGDQNSRLVRAVREGMCDSDHKRDLGGD
310 320 330 340 350 360
360 370 380 390 400
pF1KE4 AEVNPFLWHRPSEE------------DSSSMEGCHSFSASCLTQFCILFKRTFLSIMRDS
:::::::::::::: ::::::::::::::::::::::::::::::::::
NP_004 AEVNPFLWHRPSEEVKQTKRLKGLRKDSSSMEGCHSFSASCLTQFCILFKRTFLSIMRDS
370 380 390 400 410 420
410 420 430 440 450 460
pF1KE4 VLTHLRITSHIGIGLLIGLLYLGIGNEAKKVLSNSGFLFFSMLFLMFAALMPTVLTFPLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 VLTHLRITSHIGIGLLIGLLYLGIGNEAKKVLSNSGFLFFSMLFLMFAALMPTVLTFPLE
430 440 450 460 470 480
470 480 490 500 510 520
pF1KE4 MGVFLREHLNYWYSLKAYYLAKTMADVPFQIMFPVAYCSIVYWMTSQPSDAVRFVLFAAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MGVFLREHLNYWYSLKAYYLAKTMADVPFQIMFPVAYCSIVYWMTSQPSDAVRFVLFAAL
490 500 510 520 530 540
530 540 550 560 570 580
pF1KE4 GTMTSLVAQSLGLLIGAASTSLQVATFVGPVTAIPVLLFSGFFVSFDTIPTYLQWMSYIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 GTMTSLVAQSLGLLIGAASTSLQVATFVGPVTAIPVLLFSGFFVSFDTIPTYLQWMSYIS
550 560 570 580 590 600
590 600 610 620 630 640
pF1KE4 YVRYGFEGVILSIYGLDREDLHCDIDETCHFQKSEAILRELDVENAKLYLDFIVLGIFFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 YVRYGFEGVILSIYGLDREDLHCDIDETCHFQKSEAILRELDVENAKLYLDFIVLGIFFI
610 620 630 640 650 660
650 660
pF1KE4 SLRLIAYFVLRYKIRAER
::::::::::::::::::
NP_004 SLRLIAYFVLRYKIRAER
670
662 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 00:01:06 2016 done: Sun Nov 6 00:01:08 2016
Total Scan time: 10.730 Total Display time: 0.170
Function used was FASTA [36.3.4 Apr, 2011]