Result of FASTA (ccds) for
pFN21AE4548
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE4548, 647 aa
1>>>pF1KE4548 647 - 647 aa - 647 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 10.7873+/-0.00105; mu= -3.1476+/- 0.064
mean_var=330.1819+/-65.630, 0's: 0 Z-trim(114.1): 14 B-trim: 7 in 1/52
Lambda= 0.070583
statistics sampled from 14675 (14681) to 14675 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.739), E-opt: 0.2 (0.451), width: 16
Scan time: 4.520
The best scores are: opt bits E(32554)
CCDS8354.1 DLAT gene_id:1737|Hs108|chr11 ( 647) 4303 452.0 1.1e-126
CCDS44569.1 PDHX gene_id:8050|Hs108|chr11 ( 486) 781 93.3 8.4e-19
CCDS7896.1 PDHX gene_id:8050|Hs108|chr11 ( 501) 781 93.3 8.6e-19
>>CCDS8354.1 DLAT gene_id:1737|Hs108|chr11 (647 aa)
initn: 4303 init1: 4303 opt: 4303 Z-score: 2387.6 bits: 452.0 E(32554): 1.1e-126
Smith-Waterman score: 4303; 100.0% identity (100.0% similar) in 647 aa overlap (1-647:1-647)
10 20 30 40 50 60
pF1KE4 MWRVCARRAQNVAPWAGLEARWTALQEVPGTPRVTSRSGPAPARRNSVTTGYGGVRALCG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS83 MWRVCARRAQNVAPWAGLEARWTALQEVPGTPRVTSRSGPAPARRNSVTTGYGGVRALCG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 WTPSSGATPRNRLLLQLLGSPGRRYYSLPPHQKVPLPSLSPTMQAGTIARWEKKEGDKIN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS83 WTPSSGATPRNRLLLQLLGSPGRRYYSLPPHQKVPLPSLSPTMQAGTIARWEKKEGDKIN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 EGDLIAEVETDKATVGFESLEECYMAKILVAEGTRDVPIGAIICITVGKPEDIEAFKNYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS83 EGDLIAEVETDKATVGFESLEECYMAKILVAEGTRDVPIGAIICITVGKPEDIEAFKNYT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 LDSSAAPTPQAAPAPTPAATASPPTPSAQAPGSSYPPHMQVLLPALSPTMTMGTVQRWEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS83 LDSSAAPTPQAAPAPTPAATASPPTPSAQAPGSSYPPHMQVLLPALSPTMTMGTVQRWEK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 KVGEKLSEGDLLAEIETDKATIGFEVQEEGYLAKILVPEGTRDVPLGTPLCIIVEKEADI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS83 KVGEKLSEGDLLAEIETDKATIGFEVQEEGYLAKILVPEGTRDVPLGTPLCIIVEKEADI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 SAFADYRPTEVTDLKPQVPPPTPPPVAAVPPTPQPLAPTPSAPCPATPAGPKGRVFVSPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS83 SAFADYRPTEVTDLKPQVPPPTPPPVAAVPPTPQPLAPTPSAPCPATPAGPKGRVFVSPL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 AKKLAVEKGIDLTQVKGTGPDGRITKKDIDSFVPSKVAPAPAAVVPPTGPGMAPVPTGVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS83 AKKLAVEKGIDLTQVKGTGPDGRITKKDIDSFVPSKVAPAPAAVVPPTGPGMAPVPTGVF
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE4 TDIPISNIRRVIAQRLMQSKQTIPHYYLSIDVNMGEVLLVRKELNKILEGRSKISVNDFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS83 TDIPISNIRRVIAQRLMQSKQTIPHYYLSIDVNMGEVLLVRKELNKILEGRSKISVNDFI
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE4 IKASALACLKVPEANSSWMDTVIRQNHVVDVSVAVSTPAGLITPIVFNAHIKGVETIAND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS83 IKASALACLKVPEANSSWMDTVIRQNHVVDVSVAVSTPAGLITPIVFNAHIKGVETIAND
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE4 VVSLATKAREGKLQPHEFQGGTFTISNLGMFGIKNFSAIINPPQACILAIGASEDKLVPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS83 VVSLATKAREGKLQPHEFQGGTFTISNLGMFGIKNFSAIINPPQACILAIGASEDKLVPA
550 560 570 580 590 600
610 620 630 640
pF1KE4 DNEKGFDVASMMSVTLSCDHRVVDGAVGAQWLAEFRKYLEKPITMLL
:::::::::::::::::::::::::::::::::::::::::::::::
CCDS83 DNEKGFDVASMMSVTLSCDHRVVDGAVGAQWLAEFRKYLEKPITMLL
610 620 630 640
>>CCDS44569.1 PDHX gene_id:8050|Hs108|chr11 (486 aa)
initn: 1014 init1: 456 opt: 781 Z-score: 451.0 bits: 93.3 E(32554): 8.4e-19
Smith-Waterman score: 1100; 40.9% identity (66.7% similar) in 484 aa overlap (197-645:19-485)
170 180 190 200 210 220
pF1KE4 VGKPEDIEAFKNYTLDSSAAPTPQAAPAPTPAATASPPTP-SAQAPGSSYPPHMQVLLPA
:.. .::. :. :: ...:.:.
CCDS44 MQSGGAEGSPGAGRTGRGPGSGKAPPAEISSGAPDFPGGDPIKILMPS
10 20 30 40
230 240 250 260 270 280
pF1KE4 LSPTMTMGTVQRWEKKVGEKLSEGDLLAEIETDKATIGFEVQEEGYLAKILVPEGTRDVP
::::: :.. .: :: :: .: :: : :::::::.. ......: ::::.: ::....
CCDS44 LSPTMEEGNIVKWLKKEGEAVSAGDALCEIETDKAVVTLDASDDGILAKIVVEEGSKNIR
50 60 70 80 90 100
290 300 310 320 330 340
pF1KE4 LGTPLCIIVEKEADISAFADYRPTEVTDLKPQVPPPTPPPVAAVPPTPQPLAPTPSAPCP
::. . .::: :.. :.. .:. :. : ::::. : :.: .: :. :
CCDS44 LGSLIGLIVE-EGE-----DWKHVEI----PKDVGP-PPPVSK-PSEPRP-SPEPQISIP
110 120 130 140 150
350 360 370 380 390
pF1KE4 ATPAGPKG--RVFVSPLAKKLAVEKGIDLTQVKGTGPDGRITKKDIDSFVP---------
. : : .:: :... ....: .: .::: : .::.: ..:
CCDS44 VKKEHIPGTLRFRLSPAARNILEKHSLDASQGTATGPRGIFTKEDALKLVQLKQTGKITE
160 170 180 190 200 210
400 410 420 430
pF1KE4 SKVAPAPAA-------------------VVPPTG-PGMAPVPTGVFTDIPISNIRRVIAQ
:. .:::.: :.::.. ::. : .:.::.:: ::::::::.
CCDS44 SRPTPAPTATPTAPSPLQATAGPSYPRPVIPPVSTPGQ-PNAVGTFTEIPASNIRRVIAK
220 230 240 250 260 270
440 450 460 470 480 490
pF1KE4 RLMQSKQTIPHYYLSIDVNMGEVLLVRKELNKILEGRSKISVNDFIIKASALACLKVPEA
:: .::.:.:: : . : ..: :: ::..: : :.:::::::::.:.. ..:..
CCDS44 RLTESKSTVPHAYATADCDLGAVLKVRQDLVK---DDIKVSVNDFIIKAAAVTLKQMPDV
280 290 300 310 320 330
500 510 520 530 540 550
pF1KE4 NSSWMDTVIRQNHVVDVSVAVSTPAGLITPIVFNAHIKGVETIANDVVSLATKAREGKLQ
: :: .: .:.::::.: ::.:::. .: ::.. ::..: .:. :::.:::
CCDS44 NVSWDGEGPKQLPFIDISVAVATDKGLLTPIIKDAAAKGIQEIADSVKALSKKARDGKLL
340 350 360 370 380 390
560 570 580 590 600 610
pF1KE4 PHEFQGGTFTISNLGMFGIKNFSAIINPPQACILAIGASEDKLVPADNEKG---FDVASM
:.:.:::.:.::::::::: .:.:.::::::::::.: . : ...:.: .. ..
CCDS44 PEEYQGGSFSISNLGMFGIDEFTAVINPPQACILAVGRFRPVLKLTEDEEGNAKLQQRQL
400 410 420 430 440 450
620 630 640
pF1KE4 MSVTLSCDHRVVDGAVGAQWLAEFRKYLEKPITMLL
..::.: : :::: .....: :. ::.:: .
CCDS44 ITVTMSSDSRVVDDELATRFLKSFKANLENPIRLA
460 470 480
>>CCDS7896.1 PDHX gene_id:8050|Hs108|chr11 (501 aa)
initn: 1052 init1: 456 opt: 781 Z-score: 450.8 bits: 93.3 E(32554): 8.6e-19
Smith-Waterman score: 1078; 41.6% identity (67.7% similar) in 461 aa overlap (219-645:57-500)
190 200 210 220 230 240
pF1KE4 PQAAPAPTPAATASPPTPSAQAPGSSYPPHMQVLLPALSPTMTMGTVQRWEKKVGEKLSE
...:.:.::::: :.. .: :: :: .:
CCDS78 GLVKGALGWSVSRGANWRWFHSTQWLRGDPIKILMPSLSPTMEEGNIVKWLKKEGEAVSA
30 40 50 60 70 80
250 260 270 280 290 300
pF1KE4 GDLLAEIETDKATIGFEVQEEGYLAKILVPEGTRDVPLGTPLCIIVEKEADISAFADYRP
:: : :::::::.. ......: ::::.: ::.... ::. . .::: :.. :..
CCDS78 GDALCEIETDKAVVTLDASDDGILAKIVVEEGSKNIRLGSLIGLIVE-EGE-----DWKH
90 100 110 120 130 140
310 320 330 340 350 360
pF1KE4 TEVTDLKPQVPPPTPPPVAAVPPTPQPLAPTPSAPCPATPAGPKG--RVFVSPLAKKLAV
.:. :. : ::::. : :.: .: :. :. : : .:: :...
CCDS78 VEI----PKDVGP-PPPVSK-PSEPRP-SPEPQISIPVKKEHIPGTLRFRLSPAARNILE
150 160 170 180 190
370 380 390 400
pF1KE4 EKGIDLTQVKGTGPDGRITKKDIDSFVP---------SKVAPAPAA--------------
....: .: .::: : .::.: ..: :. .:::.:
CCDS78 KHSLDASQGTATGPRGIFTKEDALKLVQLKQTGKITESRPTPAPTATPTAPSPLQATAGP
200 210 220 230 240 250
410 420 430 440 450
pF1KE4 -----VVPPTG-PGMAPVPTGVFTDIPISNIRRVIAQRLMQSKQTIPHYYLSIDVNMGEV
:.::.. ::. : .:.::.:: ::::::::.:: .::.:.:: : . : ..: :
CCDS78 SYPRPVIPPVSTPGQ-PNAVGTFTEIPASNIRRVIAKRLTESKSTVPHAYATADCDLGAV
260 270 280 290 300 310
460 470 480 490 500 510
pF1KE4 LLVRKELNKILEGRSKISVNDFIIKASALACLKVPEANSSWMDTVIRQNHVVDVSVAVST
: ::..: : :.:::::::::.:.. ..:..: :: .: .:.::::.:
CCDS78 LKVRQDLVK---DDIKVSVNDFIIKAAAVTLKQMPDVNVSWDGEGPKQLPFIDISVAVAT
320 330 340 350 360
520 530 540 550 560 570
pF1KE4 PAGLITPIVFNAHIKGVETIANDVVSLATKAREGKLQPHEFQGGTFTISNLGMFGIKNFS
::.:::. .: ::.. ::..: .:. :::.::: :.:.:::.:.::::::::: .:.
CCDS78 DKGLLTPIIKDAAAKGIQEIADSVKALSKKARDGKLLPEEYQGGSFSISNLGMFGIDEFT
370 380 390 400 410 420
580 590 600 610 620 630
pF1KE4 AIINPPQACILAIGASEDKLVPADNEKG---FDVASMMSVTLSCDHRVVDGAVGAQWLAE
:.::::::::::.: . : ...:.: .. ....::.: : :::: .....:
CCDS78 AVINPPQACILAVGRFRPVLKLTEDEEGNAKLQQRQLITVTMSSDSRVVDDELATRFLKS
430 440 450 460 470 480
640
pF1KE4 FRKYLEKPITMLL
:. ::.:: .
CCDS78 FKANLENPIRLA
490 500
647 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 00:03:03 2016 done: Sun Nov 6 00:03:04 2016
Total Scan time: 4.520 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]