Result of FASTA (omim) for
pFN21AE4501
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE4501, 527 aa
1>>>pF1KE4501 527 - 527 aa - 527 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.2773+/-0.000445; mu= 18.3242+/- 0.027
mean_var=69.6403+/-14.441, 0's: 0 Z-trim(109.9): 91 B-trim: 0 in 0/50
Lambda= 0.153689
statistics sampled from 18039 (18127) to 18039 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.566), E-opt: 0.2 (0.213), width: 16
Scan time: 9.370
The best scores are: opt bits E(85289)
NP_000231 (OMIM: 300615,309850) amine oxidase [fla ( 527) 3566 800.4 0
NP_001257387 (OMIM: 300615,309850) amine oxidase [ ( 394) 2692 606.6 4.5e-173
NP_000889 (OMIM: 309860) amine oxidase [flavin-con ( 520) 2648 596.9 4.9e-170
XP_005272665 (OMIM: 309860) PREDICTED: amine oxida ( 504) 2579 581.6 1.9e-165
XP_016885012 (OMIM: 309860) PREDICTED: amine oxida ( 504) 2579 581.6 1.9e-165
XP_016885013 (OMIM: 309860) PREDICTED: amine oxida ( 504) 2579 581.6 1.9e-165
NP_690863 (OMIM: 609742) L-amino-acid oxidase isof ( 567) 356 88.7 5e-17
NP_758962 (OMIM: 609742) L-amino-acid oxidase isof ( 589) 356 88.7 5.2e-17
NP_001244946 (OMIM: 609742) L-amino-acid oxidase i ( 589) 356 88.7 5.2e-17
NP_001244947 (OMIM: 609742) L-amino-acid oxidase i ( 589) 356 88.7 5.2e-17
XP_005248985 (OMIM: 613081) PREDICTED: lysine-spec ( 678) 250 65.3 6.9e-10
XP_011512687 (OMIM: 613081) PREDICTED: lysine-spec ( 691) 250 65.3 7e-10
XP_016865934 (OMIM: 613081) PREDICTED: lysine-spec ( 700) 250 65.3 7.1e-10
XP_016865931 (OMIM: 613081) PREDICTED: lysine-spec ( 802) 250 65.3 7.9e-10
XP_005248982 (OMIM: 613081) PREDICTED: lysine-spec ( 823) 250 65.3 8.1e-10
XP_016865929 (OMIM: 613081) PREDICTED: lysine-spec ( 832) 250 65.3 8.2e-10
XP_016865932 (OMIM: 613081) PREDICTED: lysine-spec ( 832) 250 65.3 8.2e-10
NP_787034 (OMIM: 615854) spermine oxidase isoform ( 502) 205 55.2 5.5e-07
NP_787036 (OMIM: 615854) spermine oxidase isoform ( 532) 205 55.2 5.7e-07
XP_011512688 (OMIM: 613081) PREDICTED: lysine-spec ( 690) 194 52.8 3.8e-06
XP_016856206 (OMIM: 609132,616728) PREDICTED: lysi ( 802) 194 52.9 4.3e-06
XP_016856205 (OMIM: 609132,616728) PREDICTED: lysi ( 822) 194 52.9 4.4e-06
XP_005248983 (OMIM: 613081) PREDICTED: lysine-spec ( 822) 194 52.9 4.4e-06
XP_006710536 (OMIM: 609132,616728) PREDICTED: lysi ( 828) 194 52.9 4.5e-06
XP_016865930 (OMIM: 613081) PREDICTED: lysine-spec ( 831) 194 52.9 4.5e-06
NP_055828 (OMIM: 609132,616728) lysine-specific hi ( 852) 194 52.9 4.6e-06
XP_006710535 (OMIM: 609132,616728) PREDICTED: lysi ( 858) 194 52.9 4.6e-06
XP_005245843 (OMIM: 609132,616728) PREDICTED: lysi ( 872) 194 52.9 4.6e-06
XP_006710537 (OMIM: 609132,616728) PREDICTED: lysi ( 878) 194 52.9 4.7e-06
NP_001009999 (OMIM: 609132,616728) lysine-specific ( 876) 190 52.0 8.6e-06
NP_694587 (OMIM: 613081) lysine-specific histone d ( 590) 161 45.5 0.00054
NP_787035 (OMIM: 615854) spermine oxidase isoform ( 190) 154 43.6 0.00063
XP_016865935 (OMIM: 613081) PREDICTED: lysine-spec ( 464) 155 44.1 0.0011
NP_057381 (OMIM: 610995) prenylcysteine oxidase 1 ( 505) 144 41.7 0.0065
>>NP_000231 (OMIM: 300615,309850) amine oxidase [flavin- (527 aa)
initn: 3566 init1: 3566 opt: 3566 Z-score: 4273.7 bits: 800.4 E(85289): 0
Smith-Waterman score: 3566; 100.0% identity (100.0% similar) in 527 aa overlap (1-527:1-527)
10 20 30 40 50 60
pF1KE4 MENQEKASIAGHMFDVVVIGGGISGLSAAKLLTEYGVSVLVLEARDRVGGRTYTIRNEHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MENQEKASIAGHMFDVVVIGGGISGLSAAKLLTEYGVSVLVLEARDRVGGRTYTIRNEHV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 DYVDVGGAYVGPTQNRILRLSKELGIETYKVNVSERLVQYVKGKTYPFRGAFPPVWNPIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 DYVDVGGAYVGPTQNRILRLSKELGIETYKVNVSERLVQYVKGKTYPFRGAFPPVWNPIA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 YLDYNNLWRTIDNMGKEIPTDAPWEAQHADKWDKMTMKELIDKICWTKTARRFAYLFVNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 YLDYNNLWRTIDNMGKEIPTDAPWEAQHADKWDKMTMKELIDKICWTKTARRFAYLFVNI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 NVTSEPHEVSALWFLWYVKQCGGTTRIFSVTNGGQERKFVGGSGQVSERIMDLLGDQVKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 NVTSEPHEVSALWFLWYVKQCGGTTRIFSVTNGGQERKFVGGSGQVSERIMDLLGDQVKL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 NHPVTHVDQSSDNIIIETLNHEHYECKYVINAIPPTLTAKIHFRPELPAERNQLIQRLPM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 NHPVTHVDQSSDNIIIETLNHEHYECKYVINAIPPTLTAKIHFRPELPAERNQLIQRLPM
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 GAVIKCMMYYKEAFWKKKDYCGCMIIEDEDAPISITLDDTKPDGSLPAIMGFILARKADR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 GAVIKCMMYYKEAFWKKKDYCGCMIIEDEDAPISITLDDTKPDGSLPAIMGFILARKADR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 LAKLHKEIRKKKICELYAKVLGSQEALHPVHYEEKNWCEEQYSGGCYTAYFPPGIMTQYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LAKLHKEIRKKKICELYAKVLGSQEALHPVHYEEKNWCEEQYSGGCYTAYFPPGIMTQYG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE4 RVIRQPVGRIFFAGTETATKWSGYMEGAVEAGERAAREVLNGLGKVTEKDIWVQEPESKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 RVIRQPVGRIFFAGTETATKWSGYMEGAVEAGERAAREVLNGLGKVTEKDIWVQEPESKD
430 440 450 460 470 480
490 500 510 520
pF1KE4 VPAVEITHTFWERNLPSVSGLLKIIGFSTSVTALGFVLYKYKLLPRS
:::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VPAVEITHTFWERNLPSVSGLLKIIGFSTSVTALGFVLYKYKLLPRS
490 500 510 520
>>NP_001257387 (OMIM: 300615,309850) amine oxidase [flav (394 aa)
initn: 2692 init1: 2692 opt: 2692 Z-score: 3228.2 bits: 606.6 E(85289): 4.5e-173
Smith-Waterman score: 2692; 100.0% identity (100.0% similar) in 394 aa overlap (134-527:1-394)
110 120 130 140 150 160
pF1KE4 KTYPFRGAFPPVWNPIAYLDYNNLWRTIDNMGKEIPTDAPWEAQHADKWDKMTMKELIDK
::::::::::::::::::::::::::::::
NP_001 MGKEIPTDAPWEAQHADKWDKMTMKELIDK
10 20 30
170 180 190 200 210 220
pF1KE4 ICWTKTARRFAYLFVNINVTSEPHEVSALWFLWYVKQCGGTTRIFSVTNGGQERKFVGGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ICWTKTARRFAYLFVNINVTSEPHEVSALWFLWYVKQCGGTTRIFSVTNGGQERKFVGGS
40 50 60 70 80 90
230 240 250 260 270 280
pF1KE4 GQVSERIMDLLGDQVKLNHPVTHVDQSSDNIIIETLNHEHYECKYVINAIPPTLTAKIHF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GQVSERIMDLLGDQVKLNHPVTHVDQSSDNIIIETLNHEHYECKYVINAIPPTLTAKIHF
100 110 120 130 140 150
290 300 310 320 330 340
pF1KE4 RPELPAERNQLIQRLPMGAVIKCMMYYKEAFWKKKDYCGCMIIEDEDAPISITLDDTKPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RPELPAERNQLIQRLPMGAVIKCMMYYKEAFWKKKDYCGCMIIEDEDAPISITLDDTKPD
160 170 180 190 200 210
350 360 370 380 390 400
pF1KE4 GSLPAIMGFILARKADRLAKLHKEIRKKKICELYAKVLGSQEALHPVHYEEKNWCEEQYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GSLPAIMGFILARKADRLAKLHKEIRKKKICELYAKVLGSQEALHPVHYEEKNWCEEQYS
220 230 240 250 260 270
410 420 430 440 450 460
pF1KE4 GGCYTAYFPPGIMTQYGRVIRQPVGRIFFAGTETATKWSGYMEGAVEAGERAAREVLNGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GGCYTAYFPPGIMTQYGRVIRQPVGRIFFAGTETATKWSGYMEGAVEAGERAAREVLNGL
280 290 300 310 320 330
470 480 490 500 510 520
pF1KE4 GKVTEKDIWVQEPESKDVPAVEITHTFWERNLPSVSGLLKIIGFSTSVTALGFVLYKYKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GKVTEKDIWVQEPESKDVPAVEITHTFWERNLPSVSGLLKIIGFSTSVTALGFVLYKYKL
340 350 360 370 380 390
pF1KE4 LPRS
::::
NP_001 LPRS
>>NP_000889 (OMIM: 309860) amine oxidase [flavin-contain (520 aa)
initn: 2646 init1: 2611 opt: 2648 Z-score: 3173.7 bits: 596.9 E(85289): 4.9e-170
Smith-Waterman score: 2648; 73.2% identity (90.5% similar) in 514 aa overlap (15-526:6-519)
10 20 30 40 50 60
pF1KE4 MENQEKASIAGHMFDVVVIGGGISGLSAAKLLTEYGVSVLVLEARDRVGGRTYTIRNEHV
::::.::::::..::::: . :..:.::::::::::::::.::..:
NP_000 MSNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKV
10 20 30 40 50
70 80 90 100 110 120
pF1KE4 DYVDVGGAYVGPTQNRILRLSKELGIETYKVNVSERLVQYVKGKTYPFRGAFPPVWNPIA
:::.::.::::::::::::.::::.:::::: :::...::::.::::: ::::::::.
NP_000 KYVDLGGSYVGPTQNRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPIT
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE4 YLDYNNLWRTIDNMGKEIPTDAPWEAQHADKWDKMTMKELIDKICWTKTARRFAYLFVNI
:::.::.:::.:.::.:::.::::.: :..::.::::::.::.:::..:...: ::::.
NP_000 YLDHNNFWRTMDDMGREIPSDAPWKAPLAEEWDNMTMKELLDKLCWTESAKQLATLFVNL
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE4 NVTSEPHEVSALWFLWYVKQCGGTTRIFSVTNGGQERKFVGGSGQVSERIMDLLGDQVKL
::.: :::::::::::::::::::::.:.::::::::::::::::::::::::::.:::
NP_000 CVTAETHEVSALWFLWYVKQCGGTTRIISTTNGGQERKFVGGSGQVSERIMDLLGDRVKL
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE4 NHPVTHVDQSSDNIIIETLNHEHYECKYVINAIPPTLTAKIHFRPELPAERNQLIQRLPM
..:: ..::. .:...:::::: :: ::::.:::::: :::: : :: :::.: :.:.
NP_000 ERPVIYIDQTRENVLVETLNHEMYEAKYVISAIPPTLGMKIHFNPPLPMMRNQMITRVPL
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE4 GAVIKCMMYYKEAFWKKKDYCGCMIIEDEDAPISITLDDTKPDGSLPAIMGFILARKADR
:.::::..:::: ::.:::::: :::. :.::.. :::::::.:. ::::::::.:: .
NP_000 GSVIKCIVYYKEPFWRKKDYCGTMIIDGEEAPVAYTLDDTKPEGNYAAIMGFILAHKARK
300 310 320 330 340 350
370 380 390 400 410 420
pF1KE4 LAKLHKEIRKKKICELYAKVLGSQEALHPVHYEEKNWCEEQYSGGCYTAYFPPGIMTQYG
::.: :: : ::.:::::::::: :::.::::::::::::::::::::.::::::.::::
NP_000 LARLTKEERLKKLCELYAKVLGSLEALEPVHYEEKNWCEEQYSGGCYTTYFPPGILTQYG
360 370 380 390 400 410
430 440 450 460 470 480
pF1KE4 RVIRQPVGRIFFAGTETATKWSGYMEGAVEAGERAAREVLNGLGKVTEKDIWVQEPESKD
::.:::: ::.::::::::.::::::::::::::::::.:...::. : .:: .:::: :
NP_000 RVLRQPVDRIYFAGTETATHWSGYMEGAVEAGERAAREILHAMGKIPEDEIWQSEPESVD
420 430 440 450 460 470
490 500 510 520
pF1KE4 VPAVEITHTFWERNLPSVSGLLKIIGFST--SVTALGFVLYKYKLLPRS
::: :: :: ::.:::: :::..::..: :.:::::. .: :: :
NP_000 VPAQPITTTFLERHLPSVPGLLRLIGLTTIFSATALGFLAHKRGLLVRV
480 490 500 510 520
>>XP_005272665 (OMIM: 309860) PREDICTED: amine oxidase [ (504 aa)
initn: 2573 init1: 2538 opt: 2579 Z-score: 3091.2 bits: 581.6 E(85289): 1.9e-165
Smith-Waterman score: 2579; 72.8% identity (90.3% similar) in 503 aa overlap (26-526:1-503)
10 20 30 40 50 60
pF1KE4 MENQEKASIAGHMFDVVVIGGGISGLSAAKLLTEYGVSVLVLEARDRVGGRTYTIRNEHV
..::::: . :..:.::::::::::::::.::..:
XP_005 MAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKV
10 20 30
70 80 90 100 110 120
pF1KE4 DYVDVGGAYVGPTQNRILRLSKELGIETYKVNVSERLVQYVKGKTYPFRGAFPPVWNPIA
:::.::.::::::::::::.::::.:::::: :::...::::.::::: ::::::::.
XP_005 KYVDLGGSYVGPTQNRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPIT
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE4 YLDYNNLWRTIDNMGKEIPTDAPWEAQHADKWDKMTMKELIDKICWTKTARRFAYLFVNI
:::.::.:::.:.::.:::.::::.: :..::.::::::.::.:::..:...: ::::.
XP_005 YLDHNNFWRTMDDMGREIPSDAPWKAPLAEEWDNMTMKELLDKLCWTESAKQLATLFVNL
100 110 120 130 140 150
190 200 210 220 230 240
pF1KE4 NVTSEPHEVSALWFLWYVKQCGGTTRIFSVTNGGQERKFVGGSGQVSERIMDLLGDQVKL
::.: :::::::::::::::::::::.:.::::::::::::::::::::::::::.:::
XP_005 CVTAETHEVSALWFLWYVKQCGGTTRIISTTNGGQERKFVGGSGQVSERIMDLLGDRVKL
160 170 180 190 200 210
250 260 270 280 290 300
pF1KE4 NHPVTHVDQSSDNIIIETLNHEHYECKYVINAIPPTLTAKIHFRPELPAERNQLIQRLPM
..:: ..::. .:...:::::: :: ::::.:::::: :::: : :: :::.: :.:.
XP_005 ERPVIYIDQTRENVLVETLNHEMYEAKYVISAIPPTLGMKIHFNPPLPMMRNQMITRVPL
220 230 240 250 260 270
310 320 330 340 350 360
pF1KE4 GAVIKCMMYYKEAFWKKKDYCGCMIIEDEDAPISITLDDTKPDGSLPAIMGFILARKADR
:.::::..:::: ::.:::::: :::. :.::.. :::::::.:. ::::::::.:: .
XP_005 GSVIKCIVYYKEPFWRKKDYCGTMIIDGEEAPVAYTLDDTKPEGNYAAIMGFILAHKARK
280 290 300 310 320 330
370 380 390 400 410 420
pF1KE4 LAKLHKEIRKKKICELYAKVLGSQEALHPVHYEEKNWCEEQYSGGCYTAYFPPGIMTQYG
::.: :: : ::.:::::::::: :::.::::::::::::::::::::.::::::.::::
XP_005 LARLTKEERLKKLCELYAKVLGSLEALEPVHYEEKNWCEEQYSGGCYTTYFPPGILTQYG
340 350 360 370 380 390
430 440 450 460 470 480
pF1KE4 RVIRQPVGRIFFAGTETATKWSGYMEGAVEAGERAAREVLNGLGKVTEKDIWVQEPESKD
::.:::: ::.::::::::.::::::::::::::::::.:...::. : .:: .:::: :
XP_005 RVLRQPVDRIYFAGTETATHWSGYMEGAVEAGERAAREILHAMGKIPEDEIWQSEPESVD
400 410 420 430 440 450
490 500 510 520
pF1KE4 VPAVEITHTFWERNLPSVSGLLKIIGFST--SVTALGFVLYKYKLLPRS
::: :: :: ::.:::: :::..::..: :.:::::. .: :: :
XP_005 VPAQPITTTFLERHLPSVPGLLRLIGLTTIFSATALGFLAHKRGLLVRV
460 470 480 490 500
>>XP_016885012 (OMIM: 309860) PREDICTED: amine oxidase [ (504 aa)
initn: 2573 init1: 2538 opt: 2579 Z-score: 3091.2 bits: 581.6 E(85289): 1.9e-165
Smith-Waterman score: 2579; 72.8% identity (90.3% similar) in 503 aa overlap (26-526:1-503)
10 20 30 40 50 60
pF1KE4 MENQEKASIAGHMFDVVVIGGGISGLSAAKLLTEYGVSVLVLEARDRVGGRTYTIRNEHV
..::::: . :..:.::::::::::::::.::..:
XP_016 MAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKV
10 20 30
70 80 90 100 110 120
pF1KE4 DYVDVGGAYVGPTQNRILRLSKELGIETYKVNVSERLVQYVKGKTYPFRGAFPPVWNPIA
:::.::.::::::::::::.::::.:::::: :::...::::.::::: ::::::::.
XP_016 KYVDLGGSYVGPTQNRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPIT
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE4 YLDYNNLWRTIDNMGKEIPTDAPWEAQHADKWDKMTMKELIDKICWTKTARRFAYLFVNI
:::.::.:::.:.::.:::.::::.: :..::.::::::.::.:::..:...: ::::.
XP_016 YLDHNNFWRTMDDMGREIPSDAPWKAPLAEEWDNMTMKELLDKLCWTESAKQLATLFVNL
100 110 120 130 140 150
190 200 210 220 230 240
pF1KE4 NVTSEPHEVSALWFLWYVKQCGGTTRIFSVTNGGQERKFVGGSGQVSERIMDLLGDQVKL
::.: :::::::::::::::::::::.:.::::::::::::::::::::::::::.:::
XP_016 CVTAETHEVSALWFLWYVKQCGGTTRIISTTNGGQERKFVGGSGQVSERIMDLLGDRVKL
160 170 180 190 200 210
250 260 270 280 290 300
pF1KE4 NHPVTHVDQSSDNIIIETLNHEHYECKYVINAIPPTLTAKIHFRPELPAERNQLIQRLPM
..:: ..::. .:...:::::: :: ::::.:::::: :::: : :: :::.: :.:.
XP_016 ERPVIYIDQTRENVLVETLNHEMYEAKYVISAIPPTLGMKIHFNPPLPMMRNQMITRVPL
220 230 240 250 260 270
310 320 330 340 350 360
pF1KE4 GAVIKCMMYYKEAFWKKKDYCGCMIIEDEDAPISITLDDTKPDGSLPAIMGFILARKADR
:.::::..:::: ::.:::::: :::. :.::.. :::::::.:. ::::::::.:: .
XP_016 GSVIKCIVYYKEPFWRKKDYCGTMIIDGEEAPVAYTLDDTKPEGNYAAIMGFILAHKARK
280 290 300 310 320 330
370 380 390 400 410 420
pF1KE4 LAKLHKEIRKKKICELYAKVLGSQEALHPVHYEEKNWCEEQYSGGCYTAYFPPGIMTQYG
::.: :: : ::.:::::::::: :::.::::::::::::::::::::.::::::.::::
XP_016 LARLTKEERLKKLCELYAKVLGSLEALEPVHYEEKNWCEEQYSGGCYTTYFPPGILTQYG
340 350 360 370 380 390
430 440 450 460 470 480
pF1KE4 RVIRQPVGRIFFAGTETATKWSGYMEGAVEAGERAAREVLNGLGKVTEKDIWVQEPESKD
::.:::: ::.::::::::.::::::::::::::::::.:...::. : .:: .:::: :
XP_016 RVLRQPVDRIYFAGTETATHWSGYMEGAVEAGERAAREILHAMGKIPEDEIWQSEPESVD
400 410 420 430 440 450
490 500 510 520
pF1KE4 VPAVEITHTFWERNLPSVSGLLKIIGFST--SVTALGFVLYKYKLLPRS
::: :: :: ::.:::: :::..::..: :.:::::. .: :: :
XP_016 VPAQPITTTFLERHLPSVPGLLRLIGLTTIFSATALGFLAHKRGLLVRV
460 470 480 490 500
>>XP_016885013 (OMIM: 309860) PREDICTED: amine oxidase [ (504 aa)
initn: 2573 init1: 2538 opt: 2579 Z-score: 3091.2 bits: 581.6 E(85289): 1.9e-165
Smith-Waterman score: 2579; 72.8% identity (90.3% similar) in 503 aa overlap (26-526:1-503)
10 20 30 40 50 60
pF1KE4 MENQEKASIAGHMFDVVVIGGGISGLSAAKLLTEYGVSVLVLEARDRVGGRTYTIRNEHV
..::::: . :..:.::::::::::::::.::..:
XP_016 MAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKV
10 20 30
70 80 90 100 110 120
pF1KE4 DYVDVGGAYVGPTQNRILRLSKELGIETYKVNVSERLVQYVKGKTYPFRGAFPPVWNPIA
:::.::.::::::::::::.::::.:::::: :::...::::.::::: ::::::::.
XP_016 KYVDLGGSYVGPTQNRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPIT
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE4 YLDYNNLWRTIDNMGKEIPTDAPWEAQHADKWDKMTMKELIDKICWTKTARRFAYLFVNI
:::.::.:::.:.::.:::.::::.: :..::.::::::.::.:::..:...: ::::.
XP_016 YLDHNNFWRTMDDMGREIPSDAPWKAPLAEEWDNMTMKELLDKLCWTESAKQLATLFVNL
100 110 120 130 140 150
190 200 210 220 230 240
pF1KE4 NVTSEPHEVSALWFLWYVKQCGGTTRIFSVTNGGQERKFVGGSGQVSERIMDLLGDQVKL
::.: :::::::::::::::::::::.:.::::::::::::::::::::::::::.:::
XP_016 CVTAETHEVSALWFLWYVKQCGGTTRIISTTNGGQERKFVGGSGQVSERIMDLLGDRVKL
160 170 180 190 200 210
250 260 270 280 290 300
pF1KE4 NHPVTHVDQSSDNIIIETLNHEHYECKYVINAIPPTLTAKIHFRPELPAERNQLIQRLPM
..:: ..::. .:...:::::: :: ::::.:::::: :::: : :: :::.: :.:.
XP_016 ERPVIYIDQTRENVLVETLNHEMYEAKYVISAIPPTLGMKIHFNPPLPMMRNQMITRVPL
220 230 240 250 260 270
310 320 330 340 350 360
pF1KE4 GAVIKCMMYYKEAFWKKKDYCGCMIIEDEDAPISITLDDTKPDGSLPAIMGFILARKADR
:.::::..:::: ::.:::::: :::. :.::.. :::::::.:. ::::::::.:: .
XP_016 GSVIKCIVYYKEPFWRKKDYCGTMIIDGEEAPVAYTLDDTKPEGNYAAIMGFILAHKARK
280 290 300 310 320 330
370 380 390 400 410 420
pF1KE4 LAKLHKEIRKKKICELYAKVLGSQEALHPVHYEEKNWCEEQYSGGCYTAYFPPGIMTQYG
::.: :: : ::.:::::::::: :::.::::::::::::::::::::.::::::.::::
XP_016 LARLTKEERLKKLCELYAKVLGSLEALEPVHYEEKNWCEEQYSGGCYTTYFPPGILTQYG
340 350 360 370 380 390
430 440 450 460 470 480
pF1KE4 RVIRQPVGRIFFAGTETATKWSGYMEGAVEAGERAAREVLNGLGKVTEKDIWVQEPESKD
::.:::: ::.::::::::.::::::::::::::::::.:...::. : .:: .:::: :
XP_016 RVLRQPVDRIYFAGTETATHWSGYMEGAVEAGERAAREILHAMGKIPEDEIWQSEPESVD
400 410 420 430 440 450
490 500 510 520
pF1KE4 VPAVEITHTFWERNLPSVSGLLKIIGFST--SVTALGFVLYKYKLLPRS
::: :: :: ::.:::: :::..::..: :.:::::. .: :: :
XP_016 VPAQPITTTFLERHLPSVPGLLRLIGLTTIFSATALGFLAHKRGLLVRV
460 470 480 490 500
>>NP_690863 (OMIM: 609742) L-amino-acid oxidase isoform (567 aa)
initn: 331 init1: 189 opt: 356 Z-score: 426.6 bits: 88.7 E(85289): 5e-17
Smith-Waterman score: 365; 25.3% identity (52.7% similar) in 490 aa overlap (16-468:62-513)
10 20 30 40
pF1KE4 MENQEKASIAGHMFDVVVIGGGISGLSAAKLLTEYGVSVLVLEAR
:.:.:.:..:: :::.:.. : .: .:::
NP_690 PFEKCMQDPDYEQLLKVVTWGLNRTLKPQRVIVVGAGVAGLVAAKVLSDAGHKVTILEAD
40 50 60 70 80 90
50 60 70 80 90 100
pF1KE4 DRVGGRTYTIRNEHVDYVDVGGAYVGPTQNRIL-RLSKELGIETYKVNVSERLVQYVKGK
.:.::: .: :.... .. ::. :...::: .: . ::. :.. ...:: :.
NP_690 NRIGGRIFTYRDQNTGWIGELGAMRMPSSHRILHKLCQGLGL-----NLT-KFTQYDKN-
100 110 120 130 140
110 120 130 140 150
pF1KE4 TYPFRGAFPPVWNPIAYLDYNN--LWRTIDNMGKEIPTDAPWEAQHA--DKWD---KMTM
.:. . . : . .. ...: . : : :. : .. ....
NP_690 ----------TWTEVHEVKLRNYVVEKVPEKLGYAL---RPQEKGHSPEDIYQMALNQAL
150 160 170 180 190
160 170 180 190 200
pF1KE4 KELIDKICWTKTARRFA------YLFVNINVTSEPHEVSALWFLWYVKQCGG--------
:.: : :. ..: ::. . :. :.: :. .: : . :
NP_690 KDLKALGC-RKAMKKFERHTLLEYLLGEGNL-SRP----AVQLLGDVMSEDGFFYLSFAE
200 210 220 230 240
210 220 230 240 250 260
pF1KE4 TTRIFS-VTNGGQERKFVGGSGQVSERIMDLLGDQVKLNHPVTHVDQSSDNIIIETLNHE
. : : ... : ..::: . . ... :. : :: ::. . :. .. .. .
NP_690 ALRAHSCLSDRLQYSRIVGGWDLLPRALLSSLSGLVLLNAPVVAMTQGPHDVHVQIETSP
250 260 270 280 290 300
270 280 290 300 310
pF1KE4 HYECKYVINAIPPTLTA------KIHFRPELPAERNQLIQRLPMGAVIKCMMYYKEAFWK
. :..: ::: .: : : :: . .. ..:: . . : .. ... ::.
NP_690 PARNLKVLKADVVLLTASGPAVKRITFSPPLPRHMQEALRRLHYVPATKVFLSFRRPFWR
310 320 330 340 350 360
320 330 340 350 360 370
pF1KE4 KKDYCGCMIIEDEDAPISITLDDTKPDGSLPAIMGFILARKADRLAKLHKEIRKKKICEL
.. : . : : . . .:.: . .. . : .: : .: :
NP_690 EEHIEGGH--SNTDRPSRMIFYPPPREGAL-LLASYTWSDAAAAFAGLSRE-------EA
370 380 390 400 410
380 390 400 410 420
pF1KE4 YAKVLGSQEALH-PVHYEE-------KNWCEEQYSGGCYTAYFPPGIMTQYGRVIRQPVG
.: . ::: :: . : : :.:.: : ... ::.. : :
NP_690 LRLALDDVAALHGPVVRQLWDGTGVVKRWAEDQHSQGGFVVQ-PPALWQTEKDDWTVPYG
420 430 440 450 460 470
430 440 450 460 470 480
pF1KE4 RIFFAGTETATKWSGYMEGAVEAGERAAREVLNGLGKVTEKDIWVQEPESKDVPAVEITH
::.::: .:: :..: ::... ::: .. . : ...
NP_690 RIYFAGEHTAYP-HGWVETAVKSALRAAIKINSRKGPASDTASPEGHASDMEGQGHVHGV
480 490 500 510 520 530
490 500 510 520
pF1KE4 TFWERNLPSVSGLLKIIGFSTSVTALGFVLYKYKLLPRS
NP_690 ASSPSHDLAKEEGSHPPVQGQLSLQNTTHTRTSH
540 550 560
>>NP_758962 (OMIM: 609742) L-amino-acid oxidase isoform (589 aa)
initn: 331 init1: 189 opt: 356 Z-score: 426.4 bits: 88.7 E(85289): 5.2e-17
Smith-Waterman score: 365; 25.3% identity (52.7% similar) in 490 aa overlap (16-468:84-535)
10 20 30 40
pF1KE4 MENQEKASIAGHMFDVVVIGGGISGLSAAKLLTEYGVSVLVLEAR
:.:.:.:..:: :::.:.. : .: .:::
NP_758 PFEKCMQDPDYEQLLKVVTWGLNRTLKPQRVIVVGAGVAGLVAAKVLSDAGHKVTILEAD
60 70 80 90 100 110
50 60 70 80 90 100
pF1KE4 DRVGGRTYTIRNEHVDYVDVGGAYVGPTQNRIL-RLSKELGIETYKVNVSERLVQYVKGK
.:.::: .: :.... .. ::. :...::: .: . ::. :.. ...:: :.
NP_758 NRIGGRIFTYRDQNTGWIGELGAMRMPSSHRILHKLCQGLGL-----NLT-KFTQYDKN-
120 130 140 150 160
110 120 130 140 150
pF1KE4 TYPFRGAFPPVWNPIAYLDYNN--LWRTIDNMGKEIPTDAPWEAQHA--DKWD---KMTM
.:. . . : . .. ...: . : : :. : .. ....
NP_758 ----------TWTEVHEVKLRNYVVEKVPEKLGYAL---RPQEKGHSPEDIYQMALNQAL
170 180 190 200 210
160 170 180 190 200
pF1KE4 KELIDKICWTKTARRFA------YLFVNINVTSEPHEVSALWFLWYVKQCGG--------
:.: : :. ..: ::. . :. :.: :. .: : . :
NP_758 KDLKALGC-RKAMKKFERHTLLEYLLGEGNL-SRP----AVQLLGDVMSEDGFFYLSFAE
220 230 240 250 260
210 220 230 240 250 260
pF1KE4 TTRIFS-VTNGGQERKFVGGSGQVSERIMDLLGDQVKLNHPVTHVDQSSDNIIIETLNHE
. : : ... : ..::: . . ... :. : :: ::. . :. .. .. .
NP_758 ALRAHSCLSDRLQYSRIVGGWDLLPRALLSSLSGLVLLNAPVVAMTQGPHDVHVQIETSP
270 280 290 300 310 320
270 280 290 300 310
pF1KE4 HYECKYVINAIPPTLTA------KIHFRPELPAERNQLIQRLPMGAVIKCMMYYKEAFWK
. :..: ::: .: : : :: . .. ..:: . . : .. ... ::.
NP_758 PARNLKVLKADVVLLTASGPAVKRITFSPPLPRHMQEALRRLHYVPATKVFLSFRRPFWR
330 340 350 360 370 380
320 330 340 350 360 370
pF1KE4 KKDYCGCMIIEDEDAPISITLDDTKPDGSLPAIMGFILARKADRLAKLHKEIRKKKICEL
.. : . : : . . .:.: . .. . : .: : .: :
NP_758 EEHIEGGH--SNTDRPSRMIFYPPPREGAL-LLASYTWSDAAAAFAGLSRE-------EA
390 400 410 420 430
380 390 400 410 420
pF1KE4 YAKVLGSQEALH-PVHYEE-------KNWCEEQYSGGCYTAYFPPGIMTQYGRVIRQPVG
.: . ::: :: . : : :.:.: : ... ::.. : :
NP_758 LRLALDDVAALHGPVVRQLWDGTGVVKRWAEDQHSQGGFVVQ-PPALWQTEKDDWTVPYG
440 450 460 470 480 490
430 440 450 460 470 480
pF1KE4 RIFFAGTETATKWSGYMEGAVEAGERAAREVLNGLGKVTEKDIWVQEPESKDVPAVEITH
::.::: .:: :..: ::... ::: .. . : ...
NP_758 RIYFAGEHTAYP-HGWVETAVKSALRAAIKINSRKGPASDTASPEGHASDMEGQGHVHGV
500 510 520 530 540 550
490 500 510 520
pF1KE4 TFWERNLPSVSGLLKIIGFSTSVTALGFVLYKYKLLPRS
NP_758 ASSPSHDLAKEEGSHPPVQGQLSLQNTTHTRTSH
560 570 580
>>NP_001244946 (OMIM: 609742) L-amino-acid oxidase isofo (589 aa)
initn: 331 init1: 189 opt: 356 Z-score: 426.4 bits: 88.7 E(85289): 5.2e-17
Smith-Waterman score: 365; 25.3% identity (52.7% similar) in 490 aa overlap (16-468:84-535)
10 20 30 40
pF1KE4 MENQEKASIAGHMFDVVVIGGGISGLSAAKLLTEYGVSVLVLEAR
:.:.:.:..:: :::.:.. : .: .:::
NP_001 PFEKCMQDPDYEQLLKVVTWGLNRTLKPQRVIVVGAGVAGLVAAKVLSDAGHKVTILEAD
60 70 80 90 100 110
50 60 70 80 90 100
pF1KE4 DRVGGRTYTIRNEHVDYVDVGGAYVGPTQNRIL-RLSKELGIETYKVNVSERLVQYVKGK
.:.::: .: :.... .. ::. :...::: .: . ::. :.. ...:: :.
NP_001 NRIGGRIFTYRDQNTGWIGELGAMRMPSSHRILHKLCQGLGL-----NLT-KFTQYDKN-
120 130 140 150 160
110 120 130 140 150
pF1KE4 TYPFRGAFPPVWNPIAYLDYNN--LWRTIDNMGKEIPTDAPWEAQHA--DKWD---KMTM
.:. . . : . .. ...: . : : :. : .. ....
NP_001 ----------TWTEVHEVKLRNYVVEKVPEKLGYAL---RPQEKGHSPEDIYQMALNQAL
170 180 190 200 210
160 170 180 190 200
pF1KE4 KELIDKICWTKTARRFA------YLFVNINVTSEPHEVSALWFLWYVKQCGG--------
:.: : :. ..: ::. . :. :.: :. .: : . :
NP_001 KDLKALGC-RKAMKKFERHTLLEYLLGEGNL-SRP----AVQLLGDVMSEDGFFYLSFAE
220 230 240 250 260
210 220 230 240 250 260
pF1KE4 TTRIFS-VTNGGQERKFVGGSGQVSERIMDLLGDQVKLNHPVTHVDQSSDNIIIETLNHE
. : : ... : ..::: . . ... :. : :: ::. . :. .. .. .
NP_001 ALRAHSCLSDRLQYSRIVGGWDLLPRALLSSLSGLVLLNAPVVAMTQGPHDVHVQIETSP
270 280 290 300 310 320
270 280 290 300 310
pF1KE4 HYECKYVINAIPPTLTA------KIHFRPELPAERNQLIQRLPMGAVIKCMMYYKEAFWK
. :..: ::: .: : : :: . .. ..:: . . : .. ... ::.
NP_001 PARNLKVLKADVVLLTASGPAVKRITFSPPLPRHMQEALRRLHYVPATKVFLSFRRPFWR
330 340 350 360 370 380
320 330 340 350 360 370
pF1KE4 KKDYCGCMIIEDEDAPISITLDDTKPDGSLPAIMGFILARKADRLAKLHKEIRKKKICEL
.. : . : : . . .:.: . .. . : .: : .: :
NP_001 EEHIEGGH--SNTDRPSRMIFYPPPREGAL-LLASYTWSDAAAAFAGLSRE-------EA
390 400 410 420 430
380 390 400 410 420
pF1KE4 YAKVLGSQEALH-PVHYEE-------KNWCEEQYSGGCYTAYFPPGIMTQYGRVIRQPVG
.: . ::: :: . : : :.:.: : ... ::.. : :
NP_001 LRLALDDVAALHGPVVRQLWDGTGVVKRWAEDQHSQGGFVVQ-PPALWQTEKDDWTVPYG
440 450 460 470 480 490
430 440 450 460 470 480
pF1KE4 RIFFAGTETATKWSGYMEGAVEAGERAAREVLNGLGKVTEKDIWVQEPESKDVPAVEITH
::.::: .:: :..: ::... ::: .. . : ...
NP_001 RIYFAGEHTAYP-HGWVETAVKSALRAAIKINSRKGPASDTASPEGHASDMEGQGHVHGV
500 510 520 530 540 550
490 500 510 520
pF1KE4 TFWERNLPSVSGLLKIIGFSTSVTALGFVLYKYKLLPRS
NP_001 ASSPSHDLAKEEGSHPPVQGQLSLQNTTHTRTSH
560 570 580
>>NP_001244947 (OMIM: 609742) L-amino-acid oxidase isofo (589 aa)
initn: 331 init1: 189 opt: 356 Z-score: 426.4 bits: 88.7 E(85289): 5.2e-17
Smith-Waterman score: 365; 25.3% identity (52.7% similar) in 490 aa overlap (16-468:84-535)
10 20 30 40
pF1KE4 MENQEKASIAGHMFDVVVIGGGISGLSAAKLLTEYGVSVLVLEAR
:.:.:.:..:: :::.:.. : .: .:::
NP_001 PFEKCMQDPDYEQLLKVVTWGLNRTLKPQRVIVVGAGVAGLVAAKVLSDAGHKVTILEAD
60 70 80 90 100 110
50 60 70 80 90 100
pF1KE4 DRVGGRTYTIRNEHVDYVDVGGAYVGPTQNRIL-RLSKELGIETYKVNVSERLVQYVKGK
.:.::: .: :.... .. ::. :...::: .: . ::. :.. ...:: :.
NP_001 NRIGGRIFTYRDQNTGWIGELGAMRMPSSHRILHKLCQGLGL-----NLT-KFTQYDKN-
120 130 140 150 160
110 120 130 140 150
pF1KE4 TYPFRGAFPPVWNPIAYLDYNN--LWRTIDNMGKEIPTDAPWEAQHA--DKWD---KMTM
.:. . . : . .. ...: . : : :. : .. ....
NP_001 ----------TWTEVHEVKLRNYVVEKVPEKLGYAL---RPQEKGHSPEDIYQMALNQAL
170 180 190 200 210
160 170 180 190 200
pF1KE4 KELIDKICWTKTARRFA------YLFVNINVTSEPHEVSALWFLWYVKQCGG--------
:.: : :. ..: ::. . :. :.: :. .: : . :
NP_001 KDLKALGC-RKAMKKFERHTLLEYLLGEGNL-SRP----AVQLLGDVMSEDGFFYLSFAE
220 230 240 250 260
210 220 230 240 250 260
pF1KE4 TTRIFS-VTNGGQERKFVGGSGQVSERIMDLLGDQVKLNHPVTHVDQSSDNIIIETLNHE
. : : ... : ..::: . . ... :. : :: ::. . :. .. .. .
NP_001 ALRAHSCLSDRLQYSRIVGGWDLLPRALLSSLSGLVLLNAPVVAMTQGPHDVHVQIETSP
270 280 290 300 310 320
270 280 290 300 310
pF1KE4 HYECKYVINAIPPTLTA------KIHFRPELPAERNQLIQRLPMGAVIKCMMYYKEAFWK
. :..: ::: .: : : :: . .. ..:: . . : .. ... ::.
NP_001 PARNLKVLKADVVLLTASGPAVKRITFSPPLPRHMQEALRRLHYVPATKVFLSFRRPFWR
330 340 350 360 370 380
320 330 340 350 360 370
pF1KE4 KKDYCGCMIIEDEDAPISITLDDTKPDGSLPAIMGFILARKADRLAKLHKEIRKKKICEL
.. : . : : . . .:.: . .. . : .: : .: :
NP_001 EEHIEGGH--SNTDRPSRMIFYPPPREGAL-LLASYTWSDAAAAFAGLSRE-------EA
390 400 410 420 430
380 390 400 410 420
pF1KE4 YAKVLGSQEALH-PVHYEE-------KNWCEEQYSGGCYTAYFPPGIMTQYGRVIRQPVG
.: . ::: :: . : : :.:.: : ... ::.. : :
NP_001 LRLALDDVAALHGPVVRQLWDGTGVVKRWAEDQHSQGGFVVQ-PPALWQTEKDDWTVPYG
440 450 460 470 480 490
430 440 450 460 470 480
pF1KE4 RIFFAGTETATKWSGYMEGAVEAGERAAREVLNGLGKVTEKDIWVQEPESKDVPAVEITH
::.::: .:: :..: ::... ::: .. . : ...
NP_001 RIYFAGEHTAYP-HGWVETAVKSALRAAIKINSRKGPASDTASPEGHASDMEGQGHVHGV
500 510 520 530 540 550
490 500 510 520
pF1KE4 TFWERNLPSVSGLLKIIGFSTSVTALGFVLYKYKLLPRS
NP_001 ASSPSHDLAKEEGSHPPVQGQLSLQNTTHTRTSH
560 570 580
527 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 00:25:18 2016 done: Sun Nov 6 00:25:20 2016
Total Scan time: 9.370 Total Display time: 0.110
Function used was FASTA [36.3.4 Apr, 2011]