FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE4493, 513 aa
  1>>>pF1KE4493 513 - 513 aa - 513 aa
Library: human.CCDS.faa
  18511270 residues in 32554 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.4586+/-0.000701; mu= 19.7593+/- 0.043
 mean_var=103.2722+/-19.969, 0's: 0 Z-trim(113.3): 78  B-trim: 43 in 1/53
 Lambda= 0.126207
 statistics sampled from 13826 (13909) to 13826 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.756), E-opt: 0.2 (0.427), width:  16
 Scan time:  2.900

The best scores are:                                      opt bits E(32554)
CCDS45231.1 SPINT1 gene_id:6692|Hs108|chr15        ( 513) 3652 675.2 4.7e-194
CCDS10067.1 SPINT1 gene_id:6692|Hs108|chr15        ( 529) 2153 402.3  7e-112
CCDS5632.1 TFPI2 gene_id:7980|Hs108|chr7           ( 235)  362 75.8 5.9e-14


>>CCDS45231.1 SPINT1 gene_id:6692|Hs108|chr15             (513 aa)
 initn: 3652 init1: 3652 opt: 3652  Z-score: 3597.3  bits: 675.2 E(32554): 4.7e-194
Smith-Waterman score: 3652; 100.0% identity (100.0% similar) in 513 aa overlap (1-513:1-513)

               10        20        30        40        50        60
pF1KE4 MAPARTMARARLAPAGIPAVALWLLCTLGLQGTQAGPPPAPPGLPAGADCLNSFTAGVPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 MAPARTMARARLAPAGIPAVALWLLCTLGLQGTQAGPPPAPPGLPAGADCLNSFTAGVPG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE4 FVLDTNASVSNGATFLESPTVRRGWDCVRACCTTQNCNLALVELQPDRGEDAIAACFLIN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 FVLDTNASVSNGATFLESPTVRRGWDCVRACCTTQNCNLALVELQPDRGEDAIAACFLIN
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE4 CLYEQNFVCKFAPREGFINYLTREVYRSYRQLRTQGFGGSGIPKAWAGIDLKVQPQEPLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 CLYEQNFVCKFAPREGFINYLTREVYRSYRQLRTQGFGGSGIPKAWAGIDLKVQPQEPLV
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE4 LKDVENTDWRLLRGDTDVRVERKDPNQVELWGLKEGTYLFQLTVTSSDHPEDTANVTVTV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 LKDVENTDWRLLRGDTDVRVERKDPNQVELWGLKEGTYLFQLTVTSSDHPEDTANVTVTV
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE4 LSTKQTEDYCLASNKVGRCRGSFPRWYYDPTEQICKSFVYGGCLGNKNNYLREEECILAC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 LSTKQTEDYCLASNKVGRCRGSFPRWYYDPTEQICKSFVYGGCLGNKNNYLREEECILAC
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE4 RGVQGPSMERRHPVCSGTCQPTQFRCSNGCCIDSFLECDDTPNCPDASDEAACEKYTSGF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 RGVQGPSMERRHPVCSGTCQPTQFRCSNGCCIDSFLECDDTPNCPDASDEAACEKYTSGF
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KE4 DELQRIHFPSDKGHCVDLPDTGLCKESIPRWYYNPFSEHCARFTYGGCYGNKNNFEEEQQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 DELQRIHFPSDKGHCVDLPDTGLCKESIPRWYYNPFSEHCARFTYGGCYGNKNNFEEEQQ
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KE4 CLESCRGISKKDVFGLRREIPIPSTGSVEMAVAVFLVICIVVVVAILGYCFFKNQRKDFH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 CLESCRGISKKDVFGLRREIPIPSTGSVEMAVAVFLVICIVVVVAILGYCFFKNQRKDFH
              430       440       450       460       470       480

              490       500       510   
pF1KE4 GHHHHPPPTPASSTVSTTEDTEHLVYNHTTRPL
       :::::::::::::::::::::::::::::::::
CCDS45 GHHHHPPPTPASSTVSTTEDTEHLVYNHTTRPL
              490       500       510   

>>CCDS10067.1 SPINT1 gene_id:6692|Hs108|chr15             (529 aa)
 initn: 2318 init1: 2130 opt: 2153  Z-score: 2122.1  bits: 402.3 E(32554): 7e-112
Smith-Waterman score: 3610; 97.0% identity (97.0% similar) in 529 aa overlap (1-513:1-529)

               10        20        30        40        50        60
pF1KE4 MAPARTMARARLAPAGIPAVALWLLCTLGLQGTQAGPPPAPPGLPAGADCLNSFTAGVPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 MAPARTMARARLAPAGIPAVALWLLCTLGLQGTQAGPPPAPPGLPAGADCLNSFTAGVPG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE4 FVLDTNASVSNGATFLESPTVRRGWDCVRACCTTQNCNLALVELQPDRGEDAIAACFLIN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 FVLDTNASVSNGATFLESPTVRRGWDCVRACCTTQNCNLALVELQPDRGEDAIAACFLIN
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE4 CLYEQNFVCKFAPREGFINYLTREVYRSYRQLRTQGFGGSGIPKAWAGIDLKVQPQEPLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 CLYEQNFVCKFAPREGFINYLTREVYRSYRQLRTQGFGGSGIPKAWAGIDLKVQPQEPLV
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE4 LKDVENTDWRLLRGDTDVRVERKDPNQVELWGLKEGTYLFQLTVTSSDHPEDTANVTVTV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 LKDVENTDWRLLRGDTDVRVERKDPNQVELWGLKEGTYLFQLTVTSSDHPEDTANVTVTV
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE4 LSTKQTEDYCLASNKVGRCRGSFPRWYYDPTEQICKSFVYGGCLGNKNNYLREEECILAC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 LSTKQTEDYCLASNKVGRCRGSFPRWYYDPTEQICKSFVYGGCLGNKNNYLREEECILAC
              250       260       270       280       290       300

                              310       320       330       340    
pF1KE4 RGVQG----------------PSMERRHPVCSGTCQPTQFRCSNGCCIDSFLECDDTPNC
       :::::                :::::::::::::::::::::::::::::::::::::::
CCDS10 RGVQGGPLRGSSGAQATFPQGPSMERRHPVCSGTCQPTQFRCSNGCCIDSFLECDDTPNC
              310       320       330       340       350       360

          350       360       370       380       390       400    
pF1KE4 PDASDEAACEKYTSGFDELQRIHFPSDKGHCVDLPDTGLCKESIPRWYYNPFSEHCARFT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 PDASDEAACEKYTSGFDELQRIHFPSDKGHCVDLPDTGLCKESIPRWYYNPFSEHCARFT
              370       380       390       400       410       420

          410       420       430       440       450       460    
pF1KE4 YGGCYGNKNNFEEEQQCLESCRGISKKDVFGLRREIPIPSTGSVEMAVAVFLVICIVVVV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 YGGCYGNKNNFEEEQQCLESCRGISKKDVFGLRREIPIPSTGSVEMAVAVFLVICIVVVV
              430       440       450       460       470       480

          470       480       490       500       510   
pF1KE4 AILGYCFFKNQRKDFHGHHHHPPPTPASSTVSTTEDTEHLVYNHTTRPL
       :::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 AILGYCFFKNQRKDFHGHHHHPPPTPASSTVSTTEDTEHLVYNHTTRPL
              490       500       510       520         

>>CCDS5632.1 TFPI2 gene_id:7980|Hs108|chr7                (235 aa)
 initn: 364 init1: 176 opt: 362  Z-score: 364.1  bits: 75.8 E(32554): 5.9e-14
Smith-Waterman score: 362; 34.0% identity (54.8% similar) in 197 aa overlap (243-431:29-215)

            220       230       240       250       260       270  
pF1KE4 LKEGTYLFQLTVTSSDHPEDTANVTVTVLSTKQTEDYCLASNKVGRCRGSFPRWYYDPTE
                                     : .. . ::     : ::. . :.:::   
CCDS56   MDPARPLGLSILLLFLTEAALGDAAQEPTGNNAEICLLPLDYGPCRALLLRYYYDRYT
                 10        20        30        40        50        

            280       290       300        310           320       
pF1KE4 QICKSFVYGGCLGNKNNYLREEECILACRGVQG-PSMERRH----PVCSGTCQPTQFRCS
       : :..:.:::: :: ::.   : :  ::  ..  :.. : .      : :. .   :  :
CCDS56 QSCRQFLYGGCEGNANNFYTWEACDDACWRIEKVPKVCRLQVSVDDQCEGSTEKYFFNLS
       60        70        80        90       100       110        

       330         340       350       360       370       380     
pF1KE4 NGCCIDSFLE--CDDTPNCPDASDEAACEKYTSGFDELQRIHFPSDKGHCVDLPDTGLCK
       .  : ..:.   :  .       :::.:     ::   ..:  ::    : .  : :::.
CCDS56 SMTC-EKFFSGGCHRNRIENRFPDEATCM----GFCAPKKI--PS---FCYSPKDEGLCS
      120        130       140           150            160        

         390       400       410       420        430       440    
pF1KE4 ESIPRWYYNPFSEHCARFTYGGCYGNKNNFEEEQQCLESC-RGISKKDVFGLRREIPIPS
        .. :.:.::  . :  ::: :: :: :::  ...: ..: ....::             
CCDS56 ANVTRYYFNPRYRTCDAFTYTGCGGNDNNFVSREDCKRACAKALKKKKKMPKLRFASRIR
      170       180       190       200       210       220        

          450       460       470       480       490       500    
pF1KE4 TGSVEMAVAVFLVICIVVVVAILGYCFFKNQRKDFHGHHHHPPPTPASSTVSTTEDTEHL
                                                                   
CCDS56 KIRKKQF                                                     
      230                                                          




513 residues in 1 query   sequences
18511270 residues in 32554 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Mon Nov  7 18:35:06 2016 done: Mon Nov  7 18:35:07 2016
 Total Scan time:  2.900 Total Display time:  0.010

Function used was FASTA [36.3.4 Apr, 2011]