Result of FASTA (omim) for
pFN21AE4487
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE4487, 508 aa
1>>>pF1KE4487 508 - 508 aa - 508 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.3018+/-0.000414; mu= 17.9757+/- 0.026
mean_var=68.8900+/-13.912, 0's: 0 Z-trim(110.6): 80 B-trim: 197 in 1/53
Lambda= 0.154524
statistics sampled from 18944 (19024) to 18944 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.587), E-opt: 0.2 (0.223), width: 16
Scan time: 7.030
The best scores are: opt bits E(85289)
NP_001026976 (OMIM: 270200,609523) fatty aldehyde ( 508) 3337 753.5 3.2e-217
XP_011522034 (OMIM: 270200,609523) PREDICTED: fatt ( 508) 3337 753.5 3.2e-217
XP_011522035 (OMIM: 270200,609523) PREDICTED: fatt ( 508) 3337 753.5 3.2e-217
XP_016879845 (OMIM: 270200,609523) PREDICTED: fatt ( 485) 3164 714.9 1.3e-205
NP_000373 (OMIM: 270200,609523) fatty aldehyde deh ( 485) 3164 714.9 1.3e-205
XP_016879846 (OMIM: 270200,609523) PREDICTED: fatt ( 485) 3164 714.9 1.3e-205
XP_016879844 (OMIM: 270200,609523) PREDICTED: fatt ( 424) 2643 598.8 1e-170
XP_016879847 (OMIM: 270200,609523) PREDICTED: fatt ( 424) 2643 598.8 1e-170
NP_000682 (OMIM: 100660) aldehyde dehydrogenase, d ( 453) 2109 479.7 7.6e-135
NP_001128640 (OMIM: 100660) aldehyde dehydrogenase ( 453) 2109 479.7 7.6e-135
NP_001128639 (OMIM: 100660) aldehyde dehydrogenase ( 453) 2109 479.7 7.6e-135
NP_001317079 (OMIM: 100660) aldehyde dehydrogenase ( 380) 1848 421.5 2.1e-117
XP_011522033 (OMIM: 100660) PREDICTED: aldehyde de ( 380) 1848 421.5 2.1e-117
NP_001154945 (OMIM: 600466) aldehyde dehydrogenase ( 468) 1687 385.7 1.6e-106
NP_000685 (OMIM: 600466) aldehyde dehydrogenase fa ( 468) 1687 385.7 1.6e-106
XP_005256581 (OMIM: 100660) PREDICTED: aldehyde de ( 570) 1595 365.2 2.8e-100
XP_005256580 (OMIM: 100660) PREDICTED: aldehyde de ( 570) 1595 365.2 2.8e-100
XP_005256579 (OMIM: 100660) PREDICTED: aldehyde de ( 570) 1595 365.2 2.8e-100
NP_001025181 (OMIM: 600466) aldehyde dehydrogenase ( 431) 1480 339.5 1.2e-92
NP_000686 (OMIM: 601917) aldehyde dehydrogenase fa ( 385) 1362 313.2 8.9e-85
NP_001026786 (OMIM: 601917) aldehyde dehydrogenase ( 385) 1362 313.2 8.9e-85
NP_001276988 (OMIM: 600466) aldehyde dehydrogenase ( 272) 1055 244.6 2.7e-64
NP_001276987 (OMIM: 600466) aldehyde dehydrogenase ( 351) 720 170.0 1e-41
NP_000684 (OMIM: 600463,615113) aldehyde dehydroge ( 512) 536 129.1 3e-29
NP_000680 (OMIM: 100640) retinal dehydrogenase 1 [ ( 501) 521 125.7 3e-28
NP_733798 (OMIM: 603687) retinal dehydrogenase 2 i ( 422) 481 116.8 1.3e-25
NP_001193826 (OMIM: 603687) retinal dehydrogenase ( 497) 481 116.8 1.5e-25
NP_003879 (OMIM: 603687) retinal dehydrogenase 2 i ( 518) 481 116.8 1.5e-25
NP_000683 (OMIM: 100670) aldehyde dehydrogenase X, ( 517) 472 114.8 6.1e-25
XP_011516104 (OMIM: 100670) PREDICTED: aldehyde de ( 517) 472 114.8 6.1e-25
XP_011536288 (OMIM: 613584) PREDICTED: mitochondri ( 777) 470 114.5 1.2e-24
XP_016874378 (OMIM: 613584) PREDICTED: mitochondri ( 777) 470 114.5 1.2e-24
NP_001029345 (OMIM: 613584) mitochondrial 10-formy ( 923) 470 114.5 1.3e-24
NP_001071 (OMIM: 271980,610045) succinate-semialde ( 535) 460 112.2 4e-24
NP_001280744 (OMIM: 600463,615113) aldehyde dehydr ( 405) 422 103.6 1.1e-21
NP_001257294 (OMIM: 600249) cytosolic 10-formyltet ( 801) 414 102.0 6.8e-21
XP_011510657 (OMIM: 600249) PREDICTED: cytosolic 1 ( 902) 414 102.0 7.5e-21
NP_036322 (OMIM: 600249) cytosolic 10-formyltetrah ( 902) 414 102.0 7.5e-21
XP_006713544 (OMIM: 600249) PREDICTED: cytosolic 1 ( 902) 414 102.0 7.5e-21
NP_001257293 (OMIM: 600249) cytosolic 10-formyltet ( 912) 414 102.0 7.5e-21
NP_000687 (OMIM: 602733) 4-trimethylaminobutyralde ( 518) 411 101.2 7.5e-21
XP_011507596 (OMIM: 602733) PREDICTED: 4-trimethyl ( 424) 400 98.7 3.5e-20
XP_016861103 (OMIM: 600249) PREDICTED: cytosolic 1 ( 828) 391 96.9 2.4e-19
XP_016861102 (OMIM: 600249) PREDICTED: cytosolic 1 ( 838) 391 96.9 2.5e-19
NP_733797 (OMIM: 603687) retinal dehydrogenase 2 i ( 480) 361 90.1 1.6e-17
NP_001191818 (OMIM: 100650,610251) aldehyde dehydr ( 470) 360 89.8 1.8e-17
NP_000681 (OMIM: 100650,610251) aldehyde dehydroge ( 517) 360 89.9 2e-17
XP_011541719 (OMIM: 107323,266100) PREDICTED: alph ( 404) 342 85.8 2.6e-16
XP_016864982 (OMIM: 107323,266100) PREDICTED: alph ( 404) 342 85.8 2.6e-16
NP_001188306 (OMIM: 107323,266100) alpha-aminoadip ( 511) 342 85.8 3.2e-16
>>NP_001026976 (OMIM: 270200,609523) fatty aldehyde dehy (508 aa)
initn: 3337 init1: 3337 opt: 3337 Z-score: 4020.7 bits: 753.5 E(85289): 3.2e-217
Smith-Waterman score: 3337; 100.0% identity (100.0% similar) in 508 aa overlap (1-508:1-508)
10 20 30 40 50 60
pF1KE4 MELEVRRVRQAFLSGRSRPLRFRLQQLEALRRMVQEREKDILTAIAADLCKSEFNVYSQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MELEVRRVRQAFLSGRSRPLRFRLQQLEALRRMVQEREKDILTAIAADLCKSEFNVYSQE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 VITVLGEIDFMLENLPEWVTAKPVKKNVLTMLDEAYIQPQPLGVVLIIGAWNYPFVLTIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VITVLGEIDFMLENLPEWVTAKPVKKNVLTMLDEAYIQPQPLGVVLIIGAWNYPFVLTIQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 PLIGAIAAGNAVIIKPSELSENTAKILAKLLPQYLDQDLYIVINGGVEETTELLKQRFDH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PLIGAIAAGNAVIIKPSELSENTAKILAKLLPQYLDQDLYIVINGGVEETTELLKQRFDH
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 IFYTGNTAVGKIVMEAAAKHLTPVTLELGGKSPCYIDKDCDLDIVCRRITWGKYMNCGQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IFYTGNTAVGKIVMEAAAKHLTPVTLELGGKSPCYIDKDCDLDIVCRRITWGKYMNCGQT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 CIAPDYILCEASLQNQIVWKIKETVKEFYGENIKESPDYERIINLRHFKRILSLLEGQKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CIAPDYILCEASLQNQIVWKIKETVKEFYGENIKESPDYERIINLRHFKRILSLLEGQKI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 AFGGETDEATRYIAPTVLTDVDPKTKVMQEEIFGPILPIVPVKNVDEAINFINEREKPLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AFGGETDEATRYIAPTVLTDVDPKTKVMQEEIFGPILPIVPVKNVDEAINFINEREKPLA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 LYVFSHNHKLIKRMIDETSSGGVTGNDVIMHFTLNSFPFGGVGSSGMGAYHGKHSFDTFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LYVFSHNHKLIKRMIDETSSGGVTGNDVIMHFTLNSFPFGGVGSSGMGAYHGKHSFDTFS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE4 HQRPCLLKSLKREGANKLRYPPNSQSKVDWGKFFLLKRFNKEKLGLLLLTFLGIVAAVLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HQRPCLLKSLKREGANKLRYPPNSQSKVDWGKFFLLKRFNKEKLGLLLLTFLGIVAAVLV
430 440 450 460 470 480
490 500
pF1KE4 KKYQAVLRRKALLIFLVVHRLRWSSKQR
::::::::::::::::::::::::::::
NP_001 KKYQAVLRRKALLIFLVVHRLRWSSKQR
490 500
>>XP_011522034 (OMIM: 270200,609523) PREDICTED: fatty al (508 aa)
initn: 3337 init1: 3337 opt: 3337 Z-score: 4020.7 bits: 753.5 E(85289): 3.2e-217
Smith-Waterman score: 3337; 100.0% identity (100.0% similar) in 508 aa overlap (1-508:1-508)
10 20 30 40 50 60
pF1KE4 MELEVRRVRQAFLSGRSRPLRFRLQQLEALRRMVQEREKDILTAIAADLCKSEFNVYSQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MELEVRRVRQAFLSGRSRPLRFRLQQLEALRRMVQEREKDILTAIAADLCKSEFNVYSQE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 VITVLGEIDFMLENLPEWVTAKPVKKNVLTMLDEAYIQPQPLGVVLIIGAWNYPFVLTIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VITVLGEIDFMLENLPEWVTAKPVKKNVLTMLDEAYIQPQPLGVVLIIGAWNYPFVLTIQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 PLIGAIAAGNAVIIKPSELSENTAKILAKLLPQYLDQDLYIVINGGVEETTELLKQRFDH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PLIGAIAAGNAVIIKPSELSENTAKILAKLLPQYLDQDLYIVINGGVEETTELLKQRFDH
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 IFYTGNTAVGKIVMEAAAKHLTPVTLELGGKSPCYIDKDCDLDIVCRRITWGKYMNCGQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IFYTGNTAVGKIVMEAAAKHLTPVTLELGGKSPCYIDKDCDLDIVCRRITWGKYMNCGQT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 CIAPDYILCEASLQNQIVWKIKETVKEFYGENIKESPDYERIINLRHFKRILSLLEGQKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CIAPDYILCEASLQNQIVWKIKETVKEFYGENIKESPDYERIINLRHFKRILSLLEGQKI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 AFGGETDEATRYIAPTVLTDVDPKTKVMQEEIFGPILPIVPVKNVDEAINFINEREKPLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AFGGETDEATRYIAPTVLTDVDPKTKVMQEEIFGPILPIVPVKNVDEAINFINEREKPLA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 LYVFSHNHKLIKRMIDETSSGGVTGNDVIMHFTLNSFPFGGVGSSGMGAYHGKHSFDTFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LYVFSHNHKLIKRMIDETSSGGVTGNDVIMHFTLNSFPFGGVGSSGMGAYHGKHSFDTFS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE4 HQRPCLLKSLKREGANKLRYPPNSQSKVDWGKFFLLKRFNKEKLGLLLLTFLGIVAAVLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HQRPCLLKSLKREGANKLRYPPNSQSKVDWGKFFLLKRFNKEKLGLLLLTFLGIVAAVLV
430 440 450 460 470 480
490 500
pF1KE4 KKYQAVLRRKALLIFLVVHRLRWSSKQR
::::::::::::::::::::::::::::
XP_011 KKYQAVLRRKALLIFLVVHRLRWSSKQR
490 500
>>XP_011522035 (OMIM: 270200,609523) PREDICTED: fatty al (508 aa)
initn: 3337 init1: 3337 opt: 3337 Z-score: 4020.7 bits: 753.5 E(85289): 3.2e-217
Smith-Waterman score: 3337; 100.0% identity (100.0% similar) in 508 aa overlap (1-508:1-508)
10 20 30 40 50 60
pF1KE4 MELEVRRVRQAFLSGRSRPLRFRLQQLEALRRMVQEREKDILTAIAADLCKSEFNVYSQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MELEVRRVRQAFLSGRSRPLRFRLQQLEALRRMVQEREKDILTAIAADLCKSEFNVYSQE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 VITVLGEIDFMLENLPEWVTAKPVKKNVLTMLDEAYIQPQPLGVVLIIGAWNYPFVLTIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VITVLGEIDFMLENLPEWVTAKPVKKNVLTMLDEAYIQPQPLGVVLIIGAWNYPFVLTIQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 PLIGAIAAGNAVIIKPSELSENTAKILAKLLPQYLDQDLYIVINGGVEETTELLKQRFDH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PLIGAIAAGNAVIIKPSELSENTAKILAKLLPQYLDQDLYIVINGGVEETTELLKQRFDH
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 IFYTGNTAVGKIVMEAAAKHLTPVTLELGGKSPCYIDKDCDLDIVCRRITWGKYMNCGQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IFYTGNTAVGKIVMEAAAKHLTPVTLELGGKSPCYIDKDCDLDIVCRRITWGKYMNCGQT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 CIAPDYILCEASLQNQIVWKIKETVKEFYGENIKESPDYERIINLRHFKRILSLLEGQKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CIAPDYILCEASLQNQIVWKIKETVKEFYGENIKESPDYERIINLRHFKRILSLLEGQKI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 AFGGETDEATRYIAPTVLTDVDPKTKVMQEEIFGPILPIVPVKNVDEAINFINEREKPLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AFGGETDEATRYIAPTVLTDVDPKTKVMQEEIFGPILPIVPVKNVDEAINFINEREKPLA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 LYVFSHNHKLIKRMIDETSSGGVTGNDVIMHFTLNSFPFGGVGSSGMGAYHGKHSFDTFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LYVFSHNHKLIKRMIDETSSGGVTGNDVIMHFTLNSFPFGGVGSSGMGAYHGKHSFDTFS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE4 HQRPCLLKSLKREGANKLRYPPNSQSKVDWGKFFLLKRFNKEKLGLLLLTFLGIVAAVLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HQRPCLLKSLKREGANKLRYPPNSQSKVDWGKFFLLKRFNKEKLGLLLLTFLGIVAAVLV
430 440 450 460 470 480
490 500
pF1KE4 KKYQAVLRRKALLIFLVVHRLRWSSKQR
::::::::::::::::::::::::::::
XP_011 KKYQAVLRRKALLIFLVVHRLRWSSKQR
490 500
>>XP_016879845 (OMIM: 270200,609523) PREDICTED: fatty al (485 aa)
initn: 3164 init1: 3164 opt: 3164 Z-score: 3812.6 bits: 714.9 E(85289): 1.3e-205
Smith-Waterman score: 3164; 100.0% identity (100.0% similar) in 481 aa overlap (1-481:1-481)
10 20 30 40 50 60
pF1KE4 MELEVRRVRQAFLSGRSRPLRFRLQQLEALRRMVQEREKDILTAIAADLCKSEFNVYSQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MELEVRRVRQAFLSGRSRPLRFRLQQLEALRRMVQEREKDILTAIAADLCKSEFNVYSQE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 VITVLGEIDFMLENLPEWVTAKPVKKNVLTMLDEAYIQPQPLGVVLIIGAWNYPFVLTIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VITVLGEIDFMLENLPEWVTAKPVKKNVLTMLDEAYIQPQPLGVVLIIGAWNYPFVLTIQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 PLIGAIAAGNAVIIKPSELSENTAKILAKLLPQYLDQDLYIVINGGVEETTELLKQRFDH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PLIGAIAAGNAVIIKPSELSENTAKILAKLLPQYLDQDLYIVINGGVEETTELLKQRFDH
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 IFYTGNTAVGKIVMEAAAKHLTPVTLELGGKSPCYIDKDCDLDIVCRRITWGKYMNCGQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IFYTGNTAVGKIVMEAAAKHLTPVTLELGGKSPCYIDKDCDLDIVCRRITWGKYMNCGQT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 CIAPDYILCEASLQNQIVWKIKETVKEFYGENIKESPDYERIINLRHFKRILSLLEGQKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CIAPDYILCEASLQNQIVWKIKETVKEFYGENIKESPDYERIINLRHFKRILSLLEGQKI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 AFGGETDEATRYIAPTVLTDVDPKTKVMQEEIFGPILPIVPVKNVDEAINFINEREKPLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AFGGETDEATRYIAPTVLTDVDPKTKVMQEEIFGPILPIVPVKNVDEAINFINEREKPLA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 LYVFSHNHKLIKRMIDETSSGGVTGNDVIMHFTLNSFPFGGVGSSGMGAYHGKHSFDTFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LYVFSHNHKLIKRMIDETSSGGVTGNDVIMHFTLNSFPFGGVGSSGMGAYHGKHSFDTFS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE4 HQRPCLLKSLKREGANKLRYPPNSQSKVDWGKFFLLKRFNKEKLGLLLLTFLGIVAAVLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HQRPCLLKSLKREGANKLRYPPNSQSKVDWGKFFLLKRFNKEKLGLLLLTFLGIVAAVLV
430 440 450 460 470 480
490 500
pF1KE4 KKYQAVLRRKALLIFLVVHRLRWSSKQR
:
XP_016 KAEYY
>>NP_000373 (OMIM: 270200,609523) fatty aldehyde dehydro (485 aa)
initn: 3164 init1: 3164 opt: 3164 Z-score: 3812.6 bits: 714.9 E(85289): 1.3e-205
Smith-Waterman score: 3164; 100.0% identity (100.0% similar) in 481 aa overlap (1-481:1-481)
10 20 30 40 50 60
pF1KE4 MELEVRRVRQAFLSGRSRPLRFRLQQLEALRRMVQEREKDILTAIAADLCKSEFNVYSQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MELEVRRVRQAFLSGRSRPLRFRLQQLEALRRMVQEREKDILTAIAADLCKSEFNVYSQE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 VITVLGEIDFMLENLPEWVTAKPVKKNVLTMLDEAYIQPQPLGVVLIIGAWNYPFVLTIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VITVLGEIDFMLENLPEWVTAKPVKKNVLTMLDEAYIQPQPLGVVLIIGAWNYPFVLTIQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 PLIGAIAAGNAVIIKPSELSENTAKILAKLLPQYLDQDLYIVINGGVEETTELLKQRFDH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 PLIGAIAAGNAVIIKPSELSENTAKILAKLLPQYLDQDLYIVINGGVEETTELLKQRFDH
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 IFYTGNTAVGKIVMEAAAKHLTPVTLELGGKSPCYIDKDCDLDIVCRRITWGKYMNCGQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 IFYTGNTAVGKIVMEAAAKHLTPVTLELGGKSPCYIDKDCDLDIVCRRITWGKYMNCGQT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 CIAPDYILCEASLQNQIVWKIKETVKEFYGENIKESPDYERIINLRHFKRILSLLEGQKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 CIAPDYILCEASLQNQIVWKIKETVKEFYGENIKESPDYERIINLRHFKRILSLLEGQKI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 AFGGETDEATRYIAPTVLTDVDPKTKVMQEEIFGPILPIVPVKNVDEAINFINEREKPLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 AFGGETDEATRYIAPTVLTDVDPKTKVMQEEIFGPILPIVPVKNVDEAINFINEREKPLA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 LYVFSHNHKLIKRMIDETSSGGVTGNDVIMHFTLNSFPFGGVGSSGMGAYHGKHSFDTFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LYVFSHNHKLIKRMIDETSSGGVTGNDVIMHFTLNSFPFGGVGSSGMGAYHGKHSFDTFS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE4 HQRPCLLKSLKREGANKLRYPPNSQSKVDWGKFFLLKRFNKEKLGLLLLTFLGIVAAVLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 HQRPCLLKSLKREGANKLRYPPNSQSKVDWGKFFLLKRFNKEKLGLLLLTFLGIVAAVLV
430 440 450 460 470 480
490 500
pF1KE4 KKYQAVLRRKALLIFLVVHRLRWSSKQR
:
NP_000 KAEYY
>>XP_016879846 (OMIM: 270200,609523) PREDICTED: fatty al (485 aa)
initn: 3164 init1: 3164 opt: 3164 Z-score: 3812.6 bits: 714.9 E(85289): 1.3e-205
Smith-Waterman score: 3164; 100.0% identity (100.0% similar) in 481 aa overlap (1-481:1-481)
10 20 30 40 50 60
pF1KE4 MELEVRRVRQAFLSGRSRPLRFRLQQLEALRRMVQEREKDILTAIAADLCKSEFNVYSQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MELEVRRVRQAFLSGRSRPLRFRLQQLEALRRMVQEREKDILTAIAADLCKSEFNVYSQE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 VITVLGEIDFMLENLPEWVTAKPVKKNVLTMLDEAYIQPQPLGVVLIIGAWNYPFVLTIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VITVLGEIDFMLENLPEWVTAKPVKKNVLTMLDEAYIQPQPLGVVLIIGAWNYPFVLTIQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 PLIGAIAAGNAVIIKPSELSENTAKILAKLLPQYLDQDLYIVINGGVEETTELLKQRFDH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PLIGAIAAGNAVIIKPSELSENTAKILAKLLPQYLDQDLYIVINGGVEETTELLKQRFDH
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 IFYTGNTAVGKIVMEAAAKHLTPVTLELGGKSPCYIDKDCDLDIVCRRITWGKYMNCGQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IFYTGNTAVGKIVMEAAAKHLTPVTLELGGKSPCYIDKDCDLDIVCRRITWGKYMNCGQT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 CIAPDYILCEASLQNQIVWKIKETVKEFYGENIKESPDYERIINLRHFKRILSLLEGQKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CIAPDYILCEASLQNQIVWKIKETVKEFYGENIKESPDYERIINLRHFKRILSLLEGQKI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 AFGGETDEATRYIAPTVLTDVDPKTKVMQEEIFGPILPIVPVKNVDEAINFINEREKPLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AFGGETDEATRYIAPTVLTDVDPKTKVMQEEIFGPILPIVPVKNVDEAINFINEREKPLA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 LYVFSHNHKLIKRMIDETSSGGVTGNDVIMHFTLNSFPFGGVGSSGMGAYHGKHSFDTFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LYVFSHNHKLIKRMIDETSSGGVTGNDVIMHFTLNSFPFGGVGSSGMGAYHGKHSFDTFS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE4 HQRPCLLKSLKREGANKLRYPPNSQSKVDWGKFFLLKRFNKEKLGLLLLTFLGIVAAVLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HQRPCLLKSLKREGANKLRYPPNSQSKVDWGKFFLLKRFNKEKLGLLLLTFLGIVAAVLV
430 440 450 460 470 480
490 500
pF1KE4 KKYQAVLRRKALLIFLVVHRLRWSSKQR
:
XP_016 KAEYY
>>XP_016879844 (OMIM: 270200,609523) PREDICTED: fatty al (424 aa)
initn: 2643 init1: 2643 opt: 2643 Z-score: 3185.7 bits: 598.8 E(85289): 1e-170
Smith-Waterman score: 2643; 100.0% identity (100.0% similar) in 403 aa overlap (1-403:1-403)
10 20 30 40 50 60
pF1KE4 MELEVRRVRQAFLSGRSRPLRFRLQQLEALRRMVQEREKDILTAIAADLCKSEFNVYSQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MELEVRRVRQAFLSGRSRPLRFRLQQLEALRRMVQEREKDILTAIAADLCKSEFNVYSQE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 VITVLGEIDFMLENLPEWVTAKPVKKNVLTMLDEAYIQPQPLGVVLIIGAWNYPFVLTIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VITVLGEIDFMLENLPEWVTAKPVKKNVLTMLDEAYIQPQPLGVVLIIGAWNYPFVLTIQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 PLIGAIAAGNAVIIKPSELSENTAKILAKLLPQYLDQDLYIVINGGVEETTELLKQRFDH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PLIGAIAAGNAVIIKPSELSENTAKILAKLLPQYLDQDLYIVINGGVEETTELLKQRFDH
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 IFYTGNTAVGKIVMEAAAKHLTPVTLELGGKSPCYIDKDCDLDIVCRRITWGKYMNCGQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IFYTGNTAVGKIVMEAAAKHLTPVTLELGGKSPCYIDKDCDLDIVCRRITWGKYMNCGQT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 CIAPDYILCEASLQNQIVWKIKETVKEFYGENIKESPDYERIINLRHFKRILSLLEGQKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CIAPDYILCEASLQNQIVWKIKETVKEFYGENIKESPDYERIINLRHFKRILSLLEGQKI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 AFGGETDEATRYIAPTVLTDVDPKTKVMQEEIFGPILPIVPVKNVDEAINFINEREKPLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AFGGETDEATRYIAPTVLTDVDPKTKVMQEEIFGPILPIVPVKNVDEAINFINEREKPLA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 LYVFSHNHKLIKRMIDETSSGGVTGNDVIMHFTLNSFPFGGVGSSGMGAYHGKHSFDTFS
:::::::::::::::::::::::::::::::::::::::::::
XP_016 LYVFSHNHKLIKRMIDETSSGGVTGNDVIMHFTLNSFPFGGVGRILLKNDPVQPPSASTE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE4 HQRPCLLKSLKREGANKLRYPPNSQSKVDWGKFFLLKRFNKEKLGLLLLTFLGIVAAVLV
XP_016 LFLF
>>XP_016879847 (OMIM: 270200,609523) PREDICTED: fatty al (424 aa)
initn: 2643 init1: 2643 opt: 2643 Z-score: 3185.7 bits: 598.8 E(85289): 1e-170
Smith-Waterman score: 2643; 100.0% identity (100.0% similar) in 403 aa overlap (1-403:1-403)
10 20 30 40 50 60
pF1KE4 MELEVRRVRQAFLSGRSRPLRFRLQQLEALRRMVQEREKDILTAIAADLCKSEFNVYSQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MELEVRRVRQAFLSGRSRPLRFRLQQLEALRRMVQEREKDILTAIAADLCKSEFNVYSQE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 VITVLGEIDFMLENLPEWVTAKPVKKNVLTMLDEAYIQPQPLGVVLIIGAWNYPFVLTIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VITVLGEIDFMLENLPEWVTAKPVKKNVLTMLDEAYIQPQPLGVVLIIGAWNYPFVLTIQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 PLIGAIAAGNAVIIKPSELSENTAKILAKLLPQYLDQDLYIVINGGVEETTELLKQRFDH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PLIGAIAAGNAVIIKPSELSENTAKILAKLLPQYLDQDLYIVINGGVEETTELLKQRFDH
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 IFYTGNTAVGKIVMEAAAKHLTPVTLELGGKSPCYIDKDCDLDIVCRRITWGKYMNCGQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IFYTGNTAVGKIVMEAAAKHLTPVTLELGGKSPCYIDKDCDLDIVCRRITWGKYMNCGQT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 CIAPDYILCEASLQNQIVWKIKETVKEFYGENIKESPDYERIINLRHFKRILSLLEGQKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CIAPDYILCEASLQNQIVWKIKETVKEFYGENIKESPDYERIINLRHFKRILSLLEGQKI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 AFGGETDEATRYIAPTVLTDVDPKTKVMQEEIFGPILPIVPVKNVDEAINFINEREKPLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AFGGETDEATRYIAPTVLTDVDPKTKVMQEEIFGPILPIVPVKNVDEAINFINEREKPLA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 LYVFSHNHKLIKRMIDETSSGGVTGNDVIMHFTLNSFPFGGVGSSGMGAYHGKHSFDTFS
:::::::::::::::::::::::::::::::::::::::::::
XP_016 LYVFSHNHKLIKRMIDETSSGGVTGNDVIMHFTLNSFPFGGVGRILLKNDPVQPPSASTE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE4 HQRPCLLKSLKREGANKLRYPPNSQSKVDWGKFFLLKRFNKEKLGLLLLTFLGIVAAVLV
XP_016 LFLF
>>NP_000682 (OMIM: 100660) aldehyde dehydrogenase, dimer (453 aa)
initn: 2088 init1: 2088 opt: 2109 Z-score: 2541.9 bits: 479.7 E(85289): 7.6e-135
Smith-Waterman score: 2109; 67.7% identity (90.9% similar) in 439 aa overlap (5-443:8-446)
10 20 30 40 50
pF1KE4 MELEVRRVRQAFLSGRSRPLRFRLQQLEALRRMVQEREKDILTAIAADLCKSEFNVY
:.:.: :: :::.:::.::.::::::.:..::.:.... :.:::: :.:.:.:
NP_000 MSKISEAVKRARAAFSSGRTRPLQFRIQQLEALQRLIQEQEQELVGALAADLHKNEWNAY
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE4 SQEVITVLGEIDFMLENLPEWVTAKPVKKNVLTMLDEAYIQPQPLGVVLIIGAWNYPFVL
.::. :: ::..:...::::.. .::.:. :. :: ::. .::::::.::.::::: :
NP_000 YEEVVYVLEEIEYMIQKLPEWAADEPVEKTPQTQQDELYIHSEPLGVVLVIGTWNYPFNL
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE4 TIQPLIGAIAAGNAVIIKPSELSENTAKILAKLLPQYLDQDLYIVINGGVEETTELLKQR
::::..:::::::.:..:::::::: :..:: ..:::::.::: :::::: :::::::.:
NP_000 TIQPMVGAIAAGNSVVLKPSELSENMASLLATIIPQYLDKDLYPVINGGVPETTELLKER
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE4 FDHIFYTGNTAVGKIVMEAAAKHLTPVTLELGGKSPCYIDKDCDLDIVCRRITWGKYMNC
::::.:::.:.::::.: ::::::::::::::::::::.::.::::..::::.:::.::
NP_000 FDHILYTGSTGVGKIIMTAAAKHLTPVTLELGGKSPCYVDKNCDLDVACRRIAWGKFMNS
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE4 GQTCIAPDYILCEASLQNQIVWKIKETVKEFYGENIKESPDYERIINLRHFKRILSLLEG
::::.:::::::. :.::::: :.:...::::::. :.: :: :::. :::.:...:.::
NP_000 GQTCVAPDYILCDPSIQNQIVEKLKKSLKEFYGEDAKKSRDYGRIISARHFQRVMGLIEG
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE4 QKIAFGGETDEATRYIAPTVLTDVDPKTKVMQEEIFGPILPIVPVKNVDEAINFINEREK
::.:.:: : ::::::::.::::::.. :::::::::.:::: :....:::.:::.:::
NP_000 QKVAYGGTGDAATRYIAPTILTDVDPQSPVMQEEIFGPVLPIVCVRSLEEAIQFINQREK
310 320 330 340 350 360
360 370 380 390 400 410
pF1KE4 PLALYVFSHNHKLIKRMIDETSSGGVTGNDVIMHFTLNSFPFGGVGSSGMGAYHGKHSFD
:::::.:: : :.::.:: :::::::..::::.:.::.:.::::::.::::.::::.::.
NP_000 PLALYMFSSNDKVIKKMIAETSSGGVAANDVIVHITLHSLPFGGVGNSGMGSYHGKKSFE
370 380 390 400 410 420
420 430 440 450 460 470
pF1KE4 TFSHQRPCLLKSLKREGANKLRYPPNSQSKVDWGKFFLLKRFNKEKLGLLLLTFLGIVAA
::::.: ::.. : . . :.::::.
NP_000 TFSHRRSCLVRPLMNDEGLKVRYPPSPAKMTQH
430 440 450
>>NP_001128640 (OMIM: 100660) aldehyde dehydrogenase, di (453 aa)
initn: 2088 init1: 2088 opt: 2109 Z-score: 2541.9 bits: 479.7 E(85289): 7.6e-135
Smith-Waterman score: 2109; 67.7% identity (90.9% similar) in 439 aa overlap (5-443:8-446)
10 20 30 40 50
pF1KE4 MELEVRRVRQAFLSGRSRPLRFRLQQLEALRRMVQEREKDILTAIAADLCKSEFNVY
:.:.: :: :::.:::.::.::::::.:..::.:.... :.:::: :.:.:.:
NP_001 MSKISEAVKRARAAFSSGRTRPLQFRIQQLEALQRLIQEQEQELVGALAADLHKNEWNAY
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE4 SQEVITVLGEIDFMLENLPEWVTAKPVKKNVLTMLDEAYIQPQPLGVVLIIGAWNYPFVL
.::. :: ::..:...::::.. .::.:. :. :: ::. .::::::.::.::::: :
NP_001 YEEVVYVLEEIEYMIQKLPEWAADEPVEKTPQTQQDELYIHSEPLGVVLVIGTWNYPFNL
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE4 TIQPLIGAIAAGNAVIIKPSELSENTAKILAKLLPQYLDQDLYIVINGGVEETTELLKQR
::::..:::::::.:..:::::::: :..:: ..:::::.::: :::::: :::::::.:
NP_001 TIQPMVGAIAAGNSVVLKPSELSENMASLLATIIPQYLDKDLYPVINGGVPETTELLKER
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE4 FDHIFYTGNTAVGKIVMEAAAKHLTPVTLELGGKSPCYIDKDCDLDIVCRRITWGKYMNC
::::.:::.:.::::.: ::::::::::::::::::::.::.::::..::::.:::.::
NP_001 FDHILYTGSTGVGKIIMTAAAKHLTPVTLELGGKSPCYVDKNCDLDVACRRIAWGKFMNS
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE4 GQTCIAPDYILCEASLQNQIVWKIKETVKEFYGENIKESPDYERIINLRHFKRILSLLEG
::::.:::::::. :.::::: :.:...::::::. :.: :: :::. :::.:...:.::
NP_001 GQTCVAPDYILCDPSIQNQIVEKLKKSLKEFYGEDAKKSRDYGRIISARHFQRVMGLIEG
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE4 QKIAFGGETDEATRYIAPTVLTDVDPKTKVMQEEIFGPILPIVPVKNVDEAINFINEREK
::.:.:: : ::::::::.::::::.. :::::::::.:::: :....:::.:::.:::
NP_001 QKVAYGGTGDAATRYIAPTILTDVDPQSPVMQEEIFGPVLPIVCVRSLEEAIQFINQREK
310 320 330 340 350 360
360 370 380 390 400 410
pF1KE4 PLALYVFSHNHKLIKRMIDETSSGGVTGNDVIMHFTLNSFPFGGVGSSGMGAYHGKHSFD
:::::.:: : :.::.:: :::::::..::::.:.::.:.::::::.::::.::::.::.
NP_001 PLALYMFSSNDKVIKKMIAETSSGGVAANDVIVHITLHSLPFGGVGNSGMGSYHGKKSFE
370 380 390 400 410 420
420 430 440 450 460 470
pF1KE4 TFSHQRPCLLKSLKREGANKLRYPPNSQSKVDWGKFFLLKRFNKEKLGLLLLTFLGIVAA
::::.: ::.. : . . :.::::.
NP_001 TFSHRRSCLVRPLMNDEGLKVRYPPSPAKMTQH
430 440 450
508 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 00:49:03 2016 done: Sun Nov 6 00:49:05 2016
Total Scan time: 7.030 Total Display time: 0.080
Function used was FASTA [36.3.4 Apr, 2011]