Result of FASTA (omim) for
pFN21AE4484
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE4484, 500 aa
1>>>pF1KE4484 500 - 500 aa - 500 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.6545+/-0.000342; mu= 22.7106+/- 0.021
mean_var=78.0795+/-16.343, 0's: 0 Z-trim(114.6): 81 B-trim: 1641 in 1/56
Lambda= 0.145146
statistics sampled from 24490 (24581) to 24490 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.648), E-opt: 0.2 (0.288), width: 16
Scan time: 9.990
The best scores are: opt bits E(85289)
XP_011540329 (OMIM: 245340,600682,610021,616095) P ( 500) 3358 712.9 5.2e-205
NP_001159968 (OMIM: 245340,600682,610021,616095) m ( 500) 3358 712.9 5.2e-205
XP_011540328 (OMIM: 245340,600682,610021,616095) P ( 500) 3358 712.9 5.2e-205
NP_003042 (OMIM: 245340,600682,610021,616095) mono ( 500) 3358 712.9 5.2e-205
XP_005269288 (OMIM: 603654) PREDICTED: monocarboxy ( 478) 1012 221.6 3.9e-57
NP_001257551 (OMIM: 603654) monocarboxylate transp ( 478) 1012 221.6 3.9e-57
NP_004722 (OMIM: 603654) monocarboxylate transport ( 478) 1012 221.6 3.9e-57
NP_001257552 (OMIM: 603654) monocarboxylate transp ( 478) 1012 221.6 3.9e-57
XP_016875714 (OMIM: 603654) PREDICTED: monocarboxy ( 379) 955 209.6 1.3e-53
XP_016875713 (OMIM: 603654) PREDICTED: monocarboxy ( 379) 955 209.6 1.3e-53
XP_011537297 (OMIM: 603654) PREDICTED: monocarboxy ( 379) 955 209.6 1.3e-53
XP_016875716 (OMIM: 603654) PREDICTED: monocarboxy ( 379) 955 209.6 1.3e-53
XP_016875715 (OMIM: 603654) PREDICTED: monocarboxy ( 379) 955 209.6 1.3e-53
XP_011537295 (OMIM: 603654) PREDICTED: monocarboxy ( 379) 955 209.6 1.3e-53
XP_011537294 (OMIM: 603654) PREDICTED: monocarboxy ( 504) 955 209.7 1.6e-53
XP_011537291 (OMIM: 603654) PREDICTED: monocarboxy ( 504) 955 209.7 1.6e-53
XP_011537293 (OMIM: 603654) PREDICTED: monocarboxy ( 504) 955 209.7 1.6e-53
XP_011537292 (OMIM: 603654) PREDICTED: monocarboxy ( 504) 955 209.7 1.6e-53
NP_001193879 (OMIM: 603877) monocarboxylate transp ( 465) 852 188.1 4.6e-47
NP_001193881 (OMIM: 603877) monocarboxylate transp ( 465) 852 188.1 4.6e-47
NP_001035887 (OMIM: 603877) monocarboxylate transp ( 465) 852 188.1 4.6e-47
NP_004198 (OMIM: 603877) monocarboxylate transport ( 465) 852 188.1 4.6e-47
NP_001035888 (OMIM: 603877) monocarboxylate transp ( 465) 852 188.1 4.6e-47
XP_011521909 (OMIM: 603877) PREDICTED: monocarboxy ( 465) 852 188.1 4.6e-47
NP_001193880 (OMIM: 603877) monocarboxylate transp ( 465) 852 188.1 4.6e-47
NP_037488 (OMIM: 610409) monocarboxylate transport ( 504) 809 179.2 2.5e-44
XP_016884174 (OMIM: 610409) PREDICTED: monocarboxy ( 504) 809 179.2 2.5e-44
NP_001258694 (OMIM: 603879) monocarboxylate transp ( 505) 578 130.8 9.2e-30
NP_004686 (OMIM: 603879) monocarboxylate transport ( 505) 578 130.8 9.2e-30
NP_998771 (OMIM: 611910,612018) monocarboxylate tr ( 516) 578 130.8 9.3e-30
XP_016871726 (OMIM: 611910,612018) PREDICTED: mono ( 516) 578 130.8 9.3e-30
XP_016871728 (OMIM: 611910,612018) PREDICTED: mono ( 516) 578 130.8 9.3e-30
XP_016871727 (OMIM: 611910,612018) PREDICTED: mono ( 516) 578 130.8 9.3e-30
XP_011523764 (OMIM: 603879) PREDICTED: monocarboxy ( 532) 578 130.8 9.5e-30
XP_005257847 (OMIM: 603879) PREDICTED: monocarboxy ( 545) 578 130.8 9.7e-30
XP_011523763 (OMIM: 603880) PREDICTED: monocarboxy ( 523) 515 117.6 8.8e-26
NP_001167637 (OMIM: 603880) monocarboxylate transp ( 523) 515 117.6 8.8e-26
XP_016880780 (OMIM: 603880) PREDICTED: monocarboxy ( 523) 515 117.6 8.8e-26
XP_016880781 (OMIM: 603880) PREDICTED: monocarboxy ( 523) 515 117.6 8.8e-26
NP_004685 (OMIM: 603880) monocarboxylate transport ( 523) 515 117.6 8.8e-26
XP_005257846 (OMIM: 603880) PREDICTED: monocarboxy ( 527) 515 117.6 8.8e-26
NP_699188 (OMIM: 615765) monocarboxylate transport ( 471) 504 115.3 4e-25
XP_016879770 (OMIM: 615765) PREDICTED: monocarboxy ( 511) 503 115.1 4.9e-25
XP_005256545 (OMIM: 615765) PREDICTED: monocarboxy ( 566) 503 115.1 5.3e-25
XP_016871373 (OMIM: 614242) PREDICTED: monocarboxy ( 509) 393 92.0 4.2e-18
NP_919274 (OMIM: 614242) monocarboxylate transport ( 509) 393 92.0 4.2e-18
NP_001310910 (OMIM: 614242) monocarboxylate transp ( 509) 393 92.0 4.2e-18
XP_016871372 (OMIM: 614242) PREDICTED: monocarboxy ( 551) 393 92.1 4.5e-18
NP_004687 (OMIM: 603878) monocarboxylate transport ( 487) 385 90.4 1.3e-17
XP_005271374 (OMIM: 603878) PREDICTED: monocarboxy ( 487) 385 90.4 1.3e-17
>>XP_011540329 (OMIM: 245340,600682,610021,616095) PREDI (500 aa)
initn: 3358 init1: 3358 opt: 3358 Z-score: 3801.5 bits: 712.9 E(85289): 5.2e-205
Smith-Waterman score: 3358; 100.0% identity (100.0% similar) in 500 aa overlap (1-500:1-500)
10 20 30 40 50 60
pF1KE4 MPPAVGGPVGYTPPDGGWGWAVVIGAFISIGFSYAFPKSITVFFKEIEGIFHATTSEVSW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MPPAVGGPVGYTPPDGGWGWAVVIGAFISIGFSYAFPKSITVFFKEIEGIFHATTSEVSW
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 ISSIMLAVMYGGGPISSILVNKYGSRIVMIVGGCLSGCGLIAASFCNTVQQLYVCIGVIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ISSIMLAVMYGGGPISSILVNKYGSRIVMIVGGCLSGCGLIAASFCNTVQQLYVCIGVIG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 GLGLAFNLNPALTMIGKYFYKRRPLANGLAMAGSPVFLCTLAPLNQVFFGIFGWRGSFLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLGLAFNLNPALTMIGKYFYKRRPLANGLAMAGSPVFLCTLAPLNQVFFGIFGWRGSFLI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 LGGLLLNCCVAGALMRPIGPKPTKAGKDKSKASLEKAGKSGVKKDLHDANTDLIGRHPKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LGGLLLNCCVAGALMRPIGPKPTKAGKDKSKASLEKAGKSGVKKDLHDANTDLIGRHPKQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 EKRSVFQTINQFLDLTLFTHRGFLLYLSGNVIMFFGLFAPLVFLSSYGKSQHYSSEKSAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKRSVFQTINQFLDLTLFTHRGFLLYLSGNVIMFFGLFAPLVFLSSYGKSQHYSSEKSAF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 LLSILAFVDMVARPSMGLVANTKPIRPRIQYFFAASVVANGVCHMLAPLSTTYVGFCVYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLSILAFVDMVARPSMGLVANTKPIRPRIQYFFAASVVANGVCHMLAPLSTTYVGFCVYA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 GFFGFAFGWLSSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GFFGFAFGWLSSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYK
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE4 YTYWACGVVLIISGIYLFIGMGINYRLLAKEQKANEQKKESKEEETSIDVAGKPNEVTKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YTYWACGVVLIISGIYLFIGMGINYRLLAKEQKANEQKKESKEEETSIDVAGKPNEVTKA
430 440 450 460 470 480
490 500
pF1KE4 AESPDQKDTDGGPKEEESPV
::::::::::::::::::::
XP_011 AESPDQKDTDGGPKEEESPV
490 500
>>NP_001159968 (OMIM: 245340,600682,610021,616095) monoc (500 aa)
initn: 3358 init1: 3358 opt: 3358 Z-score: 3801.5 bits: 712.9 E(85289): 5.2e-205
Smith-Waterman score: 3358; 100.0% identity (100.0% similar) in 500 aa overlap (1-500:1-500)
10 20 30 40 50 60
pF1KE4 MPPAVGGPVGYTPPDGGWGWAVVIGAFISIGFSYAFPKSITVFFKEIEGIFHATTSEVSW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPPAVGGPVGYTPPDGGWGWAVVIGAFISIGFSYAFPKSITVFFKEIEGIFHATTSEVSW
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 ISSIMLAVMYGGGPISSILVNKYGSRIVMIVGGCLSGCGLIAASFCNTVQQLYVCIGVIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ISSIMLAVMYGGGPISSILVNKYGSRIVMIVGGCLSGCGLIAASFCNTVQQLYVCIGVIG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 GLGLAFNLNPALTMIGKYFYKRRPLANGLAMAGSPVFLCTLAPLNQVFFGIFGWRGSFLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GLGLAFNLNPALTMIGKYFYKRRPLANGLAMAGSPVFLCTLAPLNQVFFGIFGWRGSFLI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 LGGLLLNCCVAGALMRPIGPKPTKAGKDKSKASLEKAGKSGVKKDLHDANTDLIGRHPKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LGGLLLNCCVAGALMRPIGPKPTKAGKDKSKASLEKAGKSGVKKDLHDANTDLIGRHPKQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 EKRSVFQTINQFLDLTLFTHRGFLLYLSGNVIMFFGLFAPLVFLSSYGKSQHYSSEKSAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EKRSVFQTINQFLDLTLFTHRGFLLYLSGNVIMFFGLFAPLVFLSSYGKSQHYSSEKSAF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 LLSILAFVDMVARPSMGLVANTKPIRPRIQYFFAASVVANGVCHMLAPLSTTYVGFCVYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLSILAFVDMVARPSMGLVANTKPIRPRIQYFFAASVVANGVCHMLAPLSTTYVGFCVYA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 GFFGFAFGWLSSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GFFGFAFGWLSSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYK
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE4 YTYWACGVVLIISGIYLFIGMGINYRLLAKEQKANEQKKESKEEETSIDVAGKPNEVTKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YTYWACGVVLIISGIYLFIGMGINYRLLAKEQKANEQKKESKEEETSIDVAGKPNEVTKA
430 440 450 460 470 480
490 500
pF1KE4 AESPDQKDTDGGPKEEESPV
::::::::::::::::::::
NP_001 AESPDQKDTDGGPKEEESPV
490 500
>>XP_011540328 (OMIM: 245340,600682,610021,616095) PREDI (500 aa)
initn: 3358 init1: 3358 opt: 3358 Z-score: 3801.5 bits: 712.9 E(85289): 5.2e-205
Smith-Waterman score: 3358; 100.0% identity (100.0% similar) in 500 aa overlap (1-500:1-500)
10 20 30 40 50 60
pF1KE4 MPPAVGGPVGYTPPDGGWGWAVVIGAFISIGFSYAFPKSITVFFKEIEGIFHATTSEVSW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MPPAVGGPVGYTPPDGGWGWAVVIGAFISIGFSYAFPKSITVFFKEIEGIFHATTSEVSW
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 ISSIMLAVMYGGGPISSILVNKYGSRIVMIVGGCLSGCGLIAASFCNTVQQLYVCIGVIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ISSIMLAVMYGGGPISSILVNKYGSRIVMIVGGCLSGCGLIAASFCNTVQQLYVCIGVIG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 GLGLAFNLNPALTMIGKYFYKRRPLANGLAMAGSPVFLCTLAPLNQVFFGIFGWRGSFLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLGLAFNLNPALTMIGKYFYKRRPLANGLAMAGSPVFLCTLAPLNQVFFGIFGWRGSFLI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 LGGLLLNCCVAGALMRPIGPKPTKAGKDKSKASLEKAGKSGVKKDLHDANTDLIGRHPKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LGGLLLNCCVAGALMRPIGPKPTKAGKDKSKASLEKAGKSGVKKDLHDANTDLIGRHPKQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 EKRSVFQTINQFLDLTLFTHRGFLLYLSGNVIMFFGLFAPLVFLSSYGKSQHYSSEKSAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKRSVFQTINQFLDLTLFTHRGFLLYLSGNVIMFFGLFAPLVFLSSYGKSQHYSSEKSAF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 LLSILAFVDMVARPSMGLVANTKPIRPRIQYFFAASVVANGVCHMLAPLSTTYVGFCVYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLSILAFVDMVARPSMGLVANTKPIRPRIQYFFAASVVANGVCHMLAPLSTTYVGFCVYA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 GFFGFAFGWLSSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GFFGFAFGWLSSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYK
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE4 YTYWACGVVLIISGIYLFIGMGINYRLLAKEQKANEQKKESKEEETSIDVAGKPNEVTKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YTYWACGVVLIISGIYLFIGMGINYRLLAKEQKANEQKKESKEEETSIDVAGKPNEVTKA
430 440 450 460 470 480
490 500
pF1KE4 AESPDQKDTDGGPKEEESPV
::::::::::::::::::::
XP_011 AESPDQKDTDGGPKEEESPV
490 500
>>NP_003042 (OMIM: 245340,600682,610021,616095) monocarb (500 aa)
initn: 3358 init1: 3358 opt: 3358 Z-score: 3801.5 bits: 712.9 E(85289): 5.2e-205
Smith-Waterman score: 3358; 100.0% identity (100.0% similar) in 500 aa overlap (1-500:1-500)
10 20 30 40 50 60
pF1KE4 MPPAVGGPVGYTPPDGGWGWAVVIGAFISIGFSYAFPKSITVFFKEIEGIFHATTSEVSW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MPPAVGGPVGYTPPDGGWGWAVVIGAFISIGFSYAFPKSITVFFKEIEGIFHATTSEVSW
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 ISSIMLAVMYGGGPISSILVNKYGSRIVMIVGGCLSGCGLIAASFCNTVQQLYVCIGVIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 ISSIMLAVMYGGGPISSILVNKYGSRIVMIVGGCLSGCGLIAASFCNTVQQLYVCIGVIG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 GLGLAFNLNPALTMIGKYFYKRRPLANGLAMAGSPVFLCTLAPLNQVFFGIFGWRGSFLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 GLGLAFNLNPALTMIGKYFYKRRPLANGLAMAGSPVFLCTLAPLNQVFFGIFGWRGSFLI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 LGGLLLNCCVAGALMRPIGPKPTKAGKDKSKASLEKAGKSGVKKDLHDANTDLIGRHPKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LGGLLLNCCVAGALMRPIGPKPTKAGKDKSKASLEKAGKSGVKKDLHDANTDLIGRHPKQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 EKRSVFQTINQFLDLTLFTHRGFLLYLSGNVIMFFGLFAPLVFLSSYGKSQHYSSEKSAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 EKRSVFQTINQFLDLTLFTHRGFLLYLSGNVIMFFGLFAPLVFLSSYGKSQHYSSEKSAF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 LLSILAFVDMVARPSMGLVANTKPIRPRIQYFFAASVVANGVCHMLAPLSTTYVGFCVYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LLSILAFVDMVARPSMGLVANTKPIRPRIQYFFAASVVANGVCHMLAPLSTTYVGFCVYA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 GFFGFAFGWLSSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 GFFGFAFGWLSSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYK
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE4 YTYWACGVVLIISGIYLFIGMGINYRLLAKEQKANEQKKESKEEETSIDVAGKPNEVTKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 YTYWACGVVLIISGIYLFIGMGINYRLLAKEQKANEQKKESKEEETSIDVAGKPNEVTKA
430 440 450 460 470 480
490 500
pF1KE4 AESPDQKDTDGGPKEEESPV
::::::::::::::::::::
NP_003 AESPDQKDTDGGPKEEESPV
490 500
>>XP_005269288 (OMIM: 603654) PREDICTED: monocarboxylate (478 aa)
initn: 1907 init1: 1002 opt: 1012 Z-score: 1146.8 bits: 221.6 E(85289): 3.9e-57
Smith-Waterman score: 1931; 61.3% identity (83.2% similar) in 465 aa overlap (1-465:1-449)
10 20 30 40 50 60
pF1KE4 MPPAVGGPVGYTPPDGGWGWAVVIGAFISIGFSYAFPKSITVFFKEIEGIFHATTSEVSW
::: ..: . :::::::: :: .:::::::::::::..:::::::. :::.: ::..:
XP_005 MPPMPSAPPVHPPPDGGWGWIVVGAAFISIGFSYAFPKAVTVFFKEIQQIFHTTYSEIAW
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 ISSIMLAVMYGGGPISSILVNKYGSRIVMIVGGCLSGCGLIAASFCNTVQQLYVCIGVIG
::::::::::.:::.::.:::::::: :.:.:: : :.. ::: ..: :::. .: :
XP_005 ISSIMLAVMYAGGPVSSVLVNKYGSRPVVIAGGLLCCLGMVLASFSSSVVQLYLTMGFIT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 GLGLAFNLNPALTMIGKYFYKRRPLANGLAMAGSPVFLCTLAPLNQVFFGIFGWRGSFLI
::::::::.::::.::::::..::.::::::::::::: .:::.:: .:. :::.:::::
XP_005 GLGLAFNLQPALTIIGKYFYRKRPMANGLAMAGSPVFLSSLAPFNQYLFNTFGWKGSFLI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 LGGLLLNCCVAGALMRPIGPKPTKAGKDKSKASLEKAGKSGVKKDLHDANTDLIGRHPKQ
::.:::: ::::.::::.::. : . ::: .:.: .: :.. : .
XP_005 LGSLLLNACVAGSLMRPLGPNQTTS---KSK------NKTGKTED--DSSPKKI-----K
190 200 210 220
250 260 270 280 290 300
pF1KE4 EKRSVFQTINQFLDLTLFTHRGFLLYLSGNVIMFFGLFAPLVFLSSYGKSQHYSSEKSAF
:.:... .:..::..:: :::::.:::::::::.:.:::..::. :.:.: . ..::
XP_005 TKKSTWEKVNKYLDFSLFKHRGFLIYLSGNVIMFLGFFAPIIFLAPYAKDQGIDEYSAAF
230 240 250 260 270 280
310 320 330 340 350 360
pF1KE4 LLSILAFVDMVARPSMGLVANTKPIRPRIQYFFAASVVANGVCHMLAPLSTTYVGFCVYA
:::..::::: ::::.::.::.: :::::::::. ... :::::.: ::. :... .::
XP_005 LLSVMAFVDMFARPSVGLIANSKYIRPRIQYFFSFAIMFNGVCHLLCPLAQDYTSLVLYA
290 300 310 320 330 340
370 380 390 400 410 420
pF1KE4 GFFGFAFGWLSSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYK
:::..:: .::::::::::::: :::::::::::::: :::::::: :.: :. :.::
XP_005 VFFGLGFGSVSSVLFETLMDLVGAPRFSSAVGLVTIVECGPVLLGPPLAGKLVDLTGEYK
350 360 370 380 390 400
430 440 450 460 470 480
pF1KE4 YTYWACGVVLIISGIYLFIGMGINYRLLAKEQKANEQKKESKEEETSIDVAGKPNEVTKA
: : .::.... ....:.:: .:::::::::.: .. .....: :
XP_005 YMYMSCGAIVVAASVWLLIGNAINYRLLAKERKEENARQKTRESEPLSKSKHSEDVNVKV
410 420 430 440 450 460
490 500
pF1KE4 AESPDQKDTDGGPKEEESPV
XP_005 SNAQSVTSERETNI
470
>>NP_001257551 (OMIM: 603654) monocarboxylate transporte (478 aa)
initn: 1907 init1: 1002 opt: 1012 Z-score: 1146.8 bits: 221.6 E(85289): 3.9e-57
Smith-Waterman score: 1931; 61.3% identity (83.2% similar) in 465 aa overlap (1-465:1-449)
10 20 30 40 50 60
pF1KE4 MPPAVGGPVGYTPPDGGWGWAVVIGAFISIGFSYAFPKSITVFFKEIEGIFHATTSEVSW
::: ..: . :::::::: :: .:::::::::::::..:::::::. :::.: ::..:
NP_001 MPPMPSAPPVHPPPDGGWGWIVVGAAFISIGFSYAFPKAVTVFFKEIQQIFHTTYSEIAW
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 ISSIMLAVMYGGGPISSILVNKYGSRIVMIVGGCLSGCGLIAASFCNTVQQLYVCIGVIG
::::::::::.:::.::.:::::::: :.:.:: : :.. ::: ..: :::. .: :
NP_001 ISSIMLAVMYAGGPVSSVLVNKYGSRPVVIAGGLLCCLGMVLASFSSSVVQLYLTMGFIT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 GLGLAFNLNPALTMIGKYFYKRRPLANGLAMAGSPVFLCTLAPLNQVFFGIFGWRGSFLI
::::::::.::::.::::::..::.::::::::::::: .:::.:: .:. :::.:::::
NP_001 GLGLAFNLQPALTIIGKYFYRKRPMANGLAMAGSPVFLSSLAPFNQYLFNTFGWKGSFLI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 LGGLLLNCCVAGALMRPIGPKPTKAGKDKSKASLEKAGKSGVKKDLHDANTDLIGRHPKQ
::.:::: ::::.::::.::. : . ::: .:.: .: :.. : .
NP_001 LGSLLLNACVAGSLMRPLGPNQTTS---KSK------NKTGKTED--DSSPKKI-----K
190 200 210 220
250 260 270 280 290 300
pF1KE4 EKRSVFQTINQFLDLTLFTHRGFLLYLSGNVIMFFGLFAPLVFLSSYGKSQHYSSEKSAF
:.:... .:..::..:: :::::.:::::::::.:.:::..::. :.:.: . ..::
NP_001 TKKSTWEKVNKYLDFSLFKHRGFLIYLSGNVIMFLGFFAPIIFLAPYAKDQGIDEYSAAF
230 240 250 260 270 280
310 320 330 340 350 360
pF1KE4 LLSILAFVDMVARPSMGLVANTKPIRPRIQYFFAASVVANGVCHMLAPLSTTYVGFCVYA
:::..::::: ::::.::.::.: :::::::::. ... :::::.: ::. :... .::
NP_001 LLSVMAFVDMFARPSVGLIANSKYIRPRIQYFFSFAIMFNGVCHLLCPLAQDYTSLVLYA
290 300 310 320 330 340
370 380 390 400 410 420
pF1KE4 GFFGFAFGWLSSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYK
:::..:: .::::::::::::: :::::::::::::: :::::::: :.: :. :.::
NP_001 VFFGLGFGSVSSVLFETLMDLVGAPRFSSAVGLVTIVECGPVLLGPPLAGKLVDLTGEYK
350 360 370 380 390 400
430 440 450 460 470 480
pF1KE4 YTYWACGVVLIISGIYLFIGMGINYRLLAKEQKANEQKKESKEEETSIDVAGKPNEVTKA
: : .::.... ....:.:: .:::::::::.: .. .....: :
NP_001 YMYMSCGAIVVAASVWLLIGNAINYRLLAKERKEENARQKTRESEPLSKSKHSEDVNVKV
410 420 430 440 450 460
490 500
pF1KE4 AESPDQKDTDGGPKEEESPV
NP_001 SNAQSVTSERETNI
470
>>NP_004722 (OMIM: 603654) monocarboxylate transporter 2 (478 aa)
initn: 1907 init1: 1002 opt: 1012 Z-score: 1146.8 bits: 221.6 E(85289): 3.9e-57
Smith-Waterman score: 1931; 61.3% identity (83.2% similar) in 465 aa overlap (1-465:1-449)
10 20 30 40 50 60
pF1KE4 MPPAVGGPVGYTPPDGGWGWAVVIGAFISIGFSYAFPKSITVFFKEIEGIFHATTSEVSW
::: ..: . :::::::: :: .:::::::::::::..:::::::. :::.: ::..:
NP_004 MPPMPSAPPVHPPPDGGWGWIVVGAAFISIGFSYAFPKAVTVFFKEIQQIFHTTYSEIAW
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 ISSIMLAVMYGGGPISSILVNKYGSRIVMIVGGCLSGCGLIAASFCNTVQQLYVCIGVIG
::::::::::.:::.::.:::::::: :.:.:: : :.. ::: ..: :::. .: :
NP_004 ISSIMLAVMYAGGPVSSVLVNKYGSRPVVIAGGLLCCLGMVLASFSSSVVQLYLTMGFIT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 GLGLAFNLNPALTMIGKYFYKRRPLANGLAMAGSPVFLCTLAPLNQVFFGIFGWRGSFLI
::::::::.::::.::::::..::.::::::::::::: .:::.:: .:. :::.:::::
NP_004 GLGLAFNLQPALTIIGKYFYRKRPMANGLAMAGSPVFLSSLAPFNQYLFNTFGWKGSFLI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 LGGLLLNCCVAGALMRPIGPKPTKAGKDKSKASLEKAGKSGVKKDLHDANTDLIGRHPKQ
::.:::: ::::.::::.::. : . ::: .:.: .: :.. : .
NP_004 LGSLLLNACVAGSLMRPLGPNQTTS---KSK------NKTGKTED--DSSPKKI-----K
190 200 210 220
250 260 270 280 290 300
pF1KE4 EKRSVFQTINQFLDLTLFTHRGFLLYLSGNVIMFFGLFAPLVFLSSYGKSQHYSSEKSAF
:.:... .:..::..:: :::::.:::::::::.:.:::..::. :.:.: . ..::
NP_004 TKKSTWEKVNKYLDFSLFKHRGFLIYLSGNVIMFLGFFAPIIFLAPYAKDQGIDEYSAAF
230 240 250 260 270 280
310 320 330 340 350 360
pF1KE4 LLSILAFVDMVARPSMGLVANTKPIRPRIQYFFAASVVANGVCHMLAPLSTTYVGFCVYA
:::..::::: ::::.::.::.: :::::::::. ... :::::.: ::. :... .::
NP_004 LLSVMAFVDMFARPSVGLIANSKYIRPRIQYFFSFAIMFNGVCHLLCPLAQDYTSLVLYA
290 300 310 320 330 340
370 380 390 400 410 420
pF1KE4 GFFGFAFGWLSSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYK
:::..:: .::::::::::::: :::::::::::::: :::::::: :.: :. :.::
NP_004 VFFGLGFGSVSSVLFETLMDLVGAPRFSSAVGLVTIVECGPVLLGPPLAGKLVDLTGEYK
350 360 370 380 390 400
430 440 450 460 470 480
pF1KE4 YTYWACGVVLIISGIYLFIGMGINYRLLAKEQKANEQKKESKEEETSIDVAGKPNEVTKA
: : .::.... ....:.:: .:::::::::.: .. .....: :
NP_004 YMYMSCGAIVVAASVWLLIGNAINYRLLAKERKEENARQKTRESEPLSKSKHSEDVNVKV
410 420 430 440 450 460
490 500
pF1KE4 AESPDQKDTDGGPKEEESPV
NP_004 SNAQSVTSERETNI
470
>>NP_001257552 (OMIM: 603654) monocarboxylate transporte (478 aa)
initn: 1907 init1: 1002 opt: 1012 Z-score: 1146.8 bits: 221.6 E(85289): 3.9e-57
Smith-Waterman score: 1931; 61.3% identity (83.2% similar) in 465 aa overlap (1-465:1-449)
10 20 30 40 50 60
pF1KE4 MPPAVGGPVGYTPPDGGWGWAVVIGAFISIGFSYAFPKSITVFFKEIEGIFHATTSEVSW
::: ..: . :::::::: :: .:::::::::::::..:::::::. :::.: ::..:
NP_001 MPPMPSAPPVHPPPDGGWGWIVVGAAFISIGFSYAFPKAVTVFFKEIQQIFHTTYSEIAW
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 ISSIMLAVMYGGGPISSILVNKYGSRIVMIVGGCLSGCGLIAASFCNTVQQLYVCIGVIG
::::::::::.:::.::.:::::::: :.:.:: : :.. ::: ..: :::. .: :
NP_001 ISSIMLAVMYAGGPVSSVLVNKYGSRPVVIAGGLLCCLGMVLASFSSSVVQLYLTMGFIT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 GLGLAFNLNPALTMIGKYFYKRRPLANGLAMAGSPVFLCTLAPLNQVFFGIFGWRGSFLI
::::::::.::::.::::::..::.::::::::::::: .:::.:: .:. :::.:::::
NP_001 GLGLAFNLQPALTIIGKYFYRKRPMANGLAMAGSPVFLSSLAPFNQYLFNTFGWKGSFLI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 LGGLLLNCCVAGALMRPIGPKPTKAGKDKSKASLEKAGKSGVKKDLHDANTDLIGRHPKQ
::.:::: ::::.::::.::. : . ::: .:.: .: :.. : .
NP_001 LGSLLLNACVAGSLMRPLGPNQTTS---KSK------NKTGKTED--DSSPKKI-----K
190 200 210 220
250 260 270 280 290 300
pF1KE4 EKRSVFQTINQFLDLTLFTHRGFLLYLSGNVIMFFGLFAPLVFLSSYGKSQHYSSEKSAF
:.:... .:..::..:: :::::.:::::::::.:.:::..::. :.:.: . ..::
NP_001 TKKSTWEKVNKYLDFSLFKHRGFLIYLSGNVIMFLGFFAPIIFLAPYAKDQGIDEYSAAF
230 240 250 260 270 280
310 320 330 340 350 360
pF1KE4 LLSILAFVDMVARPSMGLVANTKPIRPRIQYFFAASVVANGVCHMLAPLSTTYVGFCVYA
:::..::::: ::::.::.::.: :::::::::. ... :::::.: ::. :... .::
NP_001 LLSVMAFVDMFARPSVGLIANSKYIRPRIQYFFSFAIMFNGVCHLLCPLAQDYTSLVLYA
290 300 310 320 330 340
370 380 390 400 410 420
pF1KE4 GFFGFAFGWLSSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYK
:::..:: .::::::::::::: :::::::::::::: :::::::: :.: :. :.::
NP_001 VFFGLGFGSVSSVLFETLMDLVGAPRFSSAVGLVTIVECGPVLLGPPLAGKLVDLTGEYK
350 360 370 380 390 400
430 440 450 460 470 480
pF1KE4 YTYWACGVVLIISGIYLFIGMGINYRLLAKEQKANEQKKESKEEETSIDVAGKPNEVTKA
: : .::.... ....:.:: .:::::::::.: .. .....: :
NP_001 YMYMSCGAIVVAASVWLLIGNAINYRLLAKERKEENARQKTRESEPLSKSKHSEDVNVKV
410 420 430 440 450 460
490 500
pF1KE4 AESPDQKDTDGGPKEEESPV
NP_001 SNAQSVTSERETNI
470
>>XP_016875714 (OMIM: 603654) PREDICTED: monocarboxylate (379 aa)
initn: 1416 init1: 919 opt: 955 Z-score: 1083.5 bits: 209.6 E(85289): 1.3e-53
Smith-Waterman score: 1445; 58.7% identity (82.5% similar) in 366 aa overlap (100-465:1-350)
70 80 90 100 110 120
pF1KE4 YGGGPISSILVNKYGSRIVMIVGGCLSGCGLIAASFCNTVQQLYVCIGVIGGLGLAFNLN
.. ::: ..: :::. .: : ::::::::.
XP_016 MVLASFSSSVVQLYLTMGFITGLGLAFNLQ
10 20 30
130 140 150 160 170 180
pF1KE4 PALTMIGKYFYKRRPLANGLAMAGSPVFLCTLAPLNQVFFGIFGWRGSFLILGGLLLNCC
::::.::::::..::.::::::::::::: .:::.:: .:. :::.:::::::.:::: :
XP_016 PALTIIGKYFYRKRPMANGLAMAGSPVFLSSLAPFNQYLFNTFGWKGSFLILGSLLLNAC
40 50 60 70 80 90
190 200 210 220 230 240
pF1KE4 VAGALMRPIGPKPTKAGKDKSKASLEKAGKSGVKKDLHDANTDLIGRHPKQEKRSVFQTI
:::.::::.::. : . ::: .:.: .: :.. : . :.:... .
XP_016 VAGSLMRPLGPNQTTS---KSK------NKTGKTED--DSSPKKI-----KTKKSTWEKV
100 110 120 130
250 260 270 280 290 300
pF1KE4 NQFLDLTLFTHRGFLLYLSGNVIMFFGLFAPLVFLSSYGKSQHYSSEKSAFLLSILAFVD
:..::..:: :::::.:::::::::.:.:::..::. :.:.: . ..:::::..::::
XP_016 NKYLDFSLFKHRGFLIYLSGNVIMFLGFFAPIIFLAPYAKDQGIDEYSAAFLLSVMAFVD
140 150 160 170 180 190
310 320 330 340 350 360
pF1KE4 MVARPSMGLVANTKPIRPRIQYFFAASVVANGVCHMLAPLSTTYVGFCVYAGFFGFAFGW
: ::::.::.::.: :::::::::. ... :::::.: ::. :... .:: :::..::
XP_016 MFARPSVGLIANSKYIRPRIQYFFSFAIMFNGVCHLLCPLAQDYTSLVLYAVFFGLGFGS
200 210 220 230 240 250
370 380 390 400 410 420
pF1KE4 LSSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYTYWACGVV
.::::::::::::: :::::::::::::: :::::::: :.: :. :.::: : .::..
XP_016 VSSVLFETLMDLVGAPRFSSAVGLVTIVECGPVLLGPPLAGKLVDLTGEYKYMYMSCGAI
260 270 280 290 300 310
430 440 450 460 470 480
pF1KE4 LIISGIYLFIGMGINYRLLAKEQKANEQKKESKEEETSIDVAGKPNEVTKAAESPDQKDT
.. ....:.:: .:::::::::.: .. .....: :
XP_016 VVAASVWLLIGNAINYRLLAKERKEENARQKTRESEPLSKSKHSEDVNVKVSNAQSVTSE
320 330 340 350 360 370
490 500
pF1KE4 DGGPKEEESPV
XP_016 RETNI
>>XP_016875713 (OMIM: 603654) PREDICTED: monocarboxylate (379 aa)
initn: 1416 init1: 919 opt: 955 Z-score: 1083.5 bits: 209.6 E(85289): 1.3e-53
Smith-Waterman score: 1445; 58.7% identity (82.5% similar) in 366 aa overlap (100-465:1-350)
70 80 90 100 110 120
pF1KE4 YGGGPISSILVNKYGSRIVMIVGGCLSGCGLIAASFCNTVQQLYVCIGVIGGLGLAFNLN
.. ::: ..: :::. .: : ::::::::.
XP_016 MVLASFSSSVVQLYLTMGFITGLGLAFNLQ
10 20 30
130 140 150 160 170 180
pF1KE4 PALTMIGKYFYKRRPLANGLAMAGSPVFLCTLAPLNQVFFGIFGWRGSFLILGGLLLNCC
::::.::::::..::.::::::::::::: .:::.:: .:. :::.:::::::.:::: :
XP_016 PALTIIGKYFYRKRPMANGLAMAGSPVFLSSLAPFNQYLFNTFGWKGSFLILGSLLLNAC
40 50 60 70 80 90
190 200 210 220 230 240
pF1KE4 VAGALMRPIGPKPTKAGKDKSKASLEKAGKSGVKKDLHDANTDLIGRHPKQEKRSVFQTI
:::.::::.::. : . ::: .:.: .: :.. : . :.:... .
XP_016 VAGSLMRPLGPNQTTS---KSK------NKTGKTED--DSSPKKI-----KTKKSTWEKV
100 110 120 130
250 260 270 280 290 300
pF1KE4 NQFLDLTLFTHRGFLLYLSGNVIMFFGLFAPLVFLSSYGKSQHYSSEKSAFLLSILAFVD
:..::..:: :::::.:::::::::.:.:::..::. :.:.: . ..:::::..::::
XP_016 NKYLDFSLFKHRGFLIYLSGNVIMFLGFFAPIIFLAPYAKDQGIDEYSAAFLLSVMAFVD
140 150 160 170 180 190
310 320 330 340 350 360
pF1KE4 MVARPSMGLVANTKPIRPRIQYFFAASVVANGVCHMLAPLSTTYVGFCVYAGFFGFAFGW
: ::::.::.::.: :::::::::. ... :::::.: ::. :... .:: :::..::
XP_016 MFARPSVGLIANSKYIRPRIQYFFSFAIMFNGVCHLLCPLAQDYTSLVLYAVFFGLGFGS
200 210 220 230 240 250
370 380 390 400 410 420
pF1KE4 LSSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYTYWACGVV
.::::::::::::: :::::::::::::: :::::::: :.: :. :.::: : .::..
XP_016 VSSVLFETLMDLVGAPRFSSAVGLVTIVECGPVLLGPPLAGKLVDLTGEYKYMYMSCGAI
260 270 280 290 300 310
430 440 450 460 470 480
pF1KE4 LIISGIYLFIGMGINYRLLAKEQKANEQKKESKEEETSIDVAGKPNEVTKAAESPDQKDT
.. ....:.:: .:::::::::.: .. .....: :
XP_016 VVAASVWLLIGNAINYRLLAKERKEENARQKTRESEPLSKSKHSEDVNVKVSNAQSVTSE
320 330 340 350 360 370
490 500
pF1KE4 DGGPKEEESPV
XP_016 RETNI
500 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 00:51:07 2016 done: Sun Nov 6 00:51:08 2016
Total Scan time: 9.990 Total Display time: 0.090
Function used was FASTA [36.3.4 Apr, 2011]