Result of FASTA (omim) for
pFN21AE4465
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE4465, 487 aa
1>>>pF1KE4465 487 - 487 aa - 487 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.7522+/-0.000495; mu= 20.8491+/- 0.030
mean_var=64.7822+/-13.541, 0's: 0 Z-trim(107.5): 84 B-trim: 0 in 0/49
Lambda= 0.159348
statistics sampled from 15456 (15540) to 15456 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.52), E-opt: 0.2 (0.182), width: 16
Scan time: 8.550
The best scores are: opt bits E(85289)
NP_055085 (OMIM: 220100,604144) B(0,+)-type amino ( 487) 3167 737.7 1.8e-212
NP_001229965 (OMIM: 220100,604144) B(0,+)-type ami ( 487) 3167 737.7 1.8e-212
NP_001119807 (OMIM: 220100,604144) B(0,+)-type ami ( 487) 3167 737.7 1.8e-212
XP_011524704 (OMIM: 220100,604144) PREDICTED: B(0, ( 487) 3167 737.7 1.8e-212
XP_016881719 (OMIM: 220100,604144) PREDICTED: B(0, ( 399) 2606 608.6 1e-173
XP_006723055 (OMIM: 220100,604144) PREDICTED: B(0, ( 260) 1645 387.5 2.4e-107
NP_055146 (OMIM: 607933) cystine/glutamate transpo ( 501) 1404 332.4 1.8e-90
NP_003477 (OMIM: 600182) large neutral amino acids ( 507) 1396 330.5 6.7e-90
XP_016879224 (OMIM: 600182) PREDICTED: large neutr ( 509) 1373 325.2 2.6e-88
XP_006720365 (OMIM: 222700,603593) PREDICTED: Y+L ( 511) 1367 323.9 6.8e-88
XP_011535600 (OMIM: 222700,603593) PREDICTED: Y+L ( 511) 1367 323.9 6.8e-88
NP_001119578 (OMIM: 222700,603593) Y+L amino acid ( 511) 1367 323.9 6.8e-88
NP_001119577 (OMIM: 222700,603593) Y+L amino acid ( 511) 1367 323.9 6.8e-88
XP_011535601 (OMIM: 222700,603593) PREDICTED: Y+L ( 511) 1367 323.9 6.8e-88
NP_003974 (OMIM: 605641) Y+L amino acid transporte ( 515) 1365 323.4 9.4e-88
XP_011521735 (OMIM: 605641) PREDICTED: Y+L amino a ( 515) 1365 323.4 9.4e-88
XP_011521740 (OMIM: 605641) PREDICTED: Y+L amino a ( 515) 1365 323.4 9.4e-88
XP_011521736 (OMIM: 605641) PREDICTED: Y+L amino a ( 515) 1365 323.4 9.4e-88
NP_001070253 (OMIM: 605641) Y+L amino acid transpo ( 515) 1365 323.4 9.4e-88
XP_011530104 (OMIM: 607933) PREDICTED: cystine/glu ( 506) 1346 319.0 1.9e-86
NP_036376 (OMIM: 604235) large neutral amino acids ( 535) 1280 303.9 7.4e-82
NP_062823 (OMIM: 607959) asc-type amino acid trans ( 523) 1250 297.0 8.7e-80
XP_006721349 (OMIM: 600182) PREDICTED: large neutr ( 352) 922 221.4 3.2e-57
XP_006723347 (OMIM: 607959) PREDICTED: asc-type am ( 444) 922 221.5 3.8e-57
XP_016879226 (OMIM: 600182) PREDICTED: large neutr ( 332) 899 216.1 1.2e-55
XP_016879340 (OMIM: 605641) PREDICTED: Y+L amino a ( 382) 874 210.4 7.2e-54
NP_001253965 (OMIM: 604235) large neutral amino ac ( 430) 834 201.3 4.6e-51
XP_011525421 (OMIM: 607959) PREDICTED: asc-type am ( 660) 818 197.7 8.1e-50
XP_011521741 (OMIM: 605641) PREDICTED: Y+L amino a ( 307) 798 192.9 1.1e-48
XP_016879225 (OMIM: 600182) PREDICTED: large neutr ( 467) 788 190.7 7.5e-48
NP_877392 (OMIM: 604235) large neutral amino acids ( 332) 734 178.2 3.1e-44
NP_001253966 (OMIM: 604235) large neutral amino ac ( 311) 587 144.4 4.5e-34
XP_011525422 (OMIM: 607959) PREDICTED: asc-type am ( 633) 345 89.0 4.3e-17
NP_004164 (OMIM: 603752) cationic amino acid trans ( 635) 313 81.6 7e-15
NP_001041629 (OMIM: 300443) cationic amino acid tr ( 619) 212 58.4 6.7e-08
XP_016885401 (OMIM: 300443) PREDICTED: cationic am ( 619) 212 58.4 6.7e-08
NP_116192 (OMIM: 300443) cationic amino acid trans ( 619) 212 58.4 6.7e-08
NP_066000 (OMIM: 615720,615725) probable cationic ( 771) 211 58.3 9.3e-08
XP_016869236 (OMIM: 601872) PREDICTED: cationic am ( 657) 205 56.8 2.1e-07
NP_003037 (OMIM: 601872) cationic amino acid trans ( 697) 205 56.8 2.2e-07
XP_005273668 (OMIM: 601872) PREDICTED: cationic am ( 658) 203 56.4 2.9e-07
XP_005273669 (OMIM: 601872) PREDICTED: cationic am ( 658) 203 56.4 2.9e-07
XP_016869235 (OMIM: 601872) PREDICTED: cationic am ( 658) 203 56.4 2.9e-07
NP_001008539 (OMIM: 601872) cationic amino acid tr ( 658) 203 56.4 2.9e-07
XP_005273667 (OMIM: 601872) PREDICTED: cationic am ( 658) 203 56.4 2.9e-07
NP_001158243 (OMIM: 601872) cationic amino acid tr ( 698) 203 56.4 3.1e-07
XP_016876205 (OMIM: 104615) PREDICTED: high affini ( 629) 181 51.3 9.5e-06
XP_005266564 (OMIM: 104615) PREDICTED: high affini ( 629) 181 51.3 9.5e-06
NP_003036 (OMIM: 104615) high affinity cationic am ( 629) 181 51.3 9.5e-06
XP_016876204 (OMIM: 104615) PREDICTED: high affini ( 643) 181 51.3 9.6e-06
>>NP_055085 (OMIM: 220100,604144) B(0,+)-type amino acid (487 aa)
initn: 3167 init1: 3167 opt: 3167 Z-score: 3935.6 bits: 737.7 E(85289): 1.8e-212
Smith-Waterman score: 3167; 100.0% identity (100.0% similar) in 487 aa overlap (1-487:1-487)
10 20 30 40 50 60
pF1KE4 MGDTGLRKRREDEKSIQSQEPKTTSLQKELGLISGISIIVGTIIGSGIFVSPKSVLSNTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MGDTGLRKRREDEKSIQSQEPKTTSLQKELGLISGISIIVGTIIGSGIFVSPKSVLSNTE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 AVGPCLIIWAACGVLATLGALCFAELGTMITKSGGEYPYLMEAYGPIPAYLFSWASLIVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 AVGPCLIIWAACGVLATLGALCFAELGTMITKSGGEYPYLMEAYGPIPAYLFSWASLIVI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 KPTSFAIICLSFSEYVCAPFYVGCKPPQIVVKCLAAAAILFISTVNSLSVRLGSYVQNIF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 KPTSFAIICLSFSEYVCAPFYVGCKPPQIVVKCLAAAAILFISTVNSLSVRLGSYVQNIF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 TAAKLVIVAIIIISGLVLLAQGNTKNFDNSFEGAQLSVGAISLAFYNGLWAYDGWNQLNY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 TAAKLVIVAIIIISGLVLLAQGNTKNFDNSFEGAQLSVGAISLAFYNGLWAYDGWNQLNY
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 ITEELRNPYRNLPLAIIIGIPLVTACYILMNVSYFTVMTATELLQSQAVAVTFGDRVLYP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 ITEELRNPYRNLPLAIIIGIPLVTACYILMNVSYFTVMTATELLQSQAVAVTFGDRVLYP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 ASWIVPLFVAFSTIGAANGTCFTAGRLIYVAGREGHMLKVLSYISVRRLTPAPAIIFYGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 ASWIVPLFVAFSTIGAANGTCFTAGRLIYVAGREGHMLKVLSYISVRRLTPAPAIIFYGI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 IATIYIIPGDINSLVNYFSFAAWLFYGLTILGLIVMRFTRKELERPIKVPVVIPVLMTLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 IATIYIIPGDINSLVNYFSFAAWLFYGLTILGLIVMRFTRKELERPIKVPVVIPVLMTLI
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE4 SVFLVLAPIISKPTWEYLYCVLFILSGLLFYFLFVHYKFGWAQKISKPITMHLQMLMEVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SVFLVLAPIISKPTWEYLYCVLFILSGLLFYFLFVHYKFGWAQKISKPITMHLQMLMEVV
430 440 450 460 470 480
pF1KE4 PPEEDPE
:::::::
NP_055 PPEEDPE
>>NP_001229965 (OMIM: 220100,604144) B(0,+)-type amino a (487 aa)
initn: 3167 init1: 3167 opt: 3167 Z-score: 3935.6 bits: 737.7 E(85289): 1.8e-212
Smith-Waterman score: 3167; 100.0% identity (100.0% similar) in 487 aa overlap (1-487:1-487)
10 20 30 40 50 60
pF1KE4 MGDTGLRKRREDEKSIQSQEPKTTSLQKELGLISGISIIVGTIIGSGIFVSPKSVLSNTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGDTGLRKRREDEKSIQSQEPKTTSLQKELGLISGISIIVGTIIGSGIFVSPKSVLSNTE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 AVGPCLIIWAACGVLATLGALCFAELGTMITKSGGEYPYLMEAYGPIPAYLFSWASLIVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AVGPCLIIWAACGVLATLGALCFAELGTMITKSGGEYPYLMEAYGPIPAYLFSWASLIVI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 KPTSFAIICLSFSEYVCAPFYVGCKPPQIVVKCLAAAAILFISTVNSLSVRLGSYVQNIF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KPTSFAIICLSFSEYVCAPFYVGCKPPQIVVKCLAAAAILFISTVNSLSVRLGSYVQNIF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 TAAKLVIVAIIIISGLVLLAQGNTKNFDNSFEGAQLSVGAISLAFYNGLWAYDGWNQLNY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TAAKLVIVAIIIISGLVLLAQGNTKNFDNSFEGAQLSVGAISLAFYNGLWAYDGWNQLNY
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 ITEELRNPYRNLPLAIIIGIPLVTACYILMNVSYFTVMTATELLQSQAVAVTFGDRVLYP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ITEELRNPYRNLPLAIIIGIPLVTACYILMNVSYFTVMTATELLQSQAVAVTFGDRVLYP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 ASWIVPLFVAFSTIGAANGTCFTAGRLIYVAGREGHMLKVLSYISVRRLTPAPAIIFYGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ASWIVPLFVAFSTIGAANGTCFTAGRLIYVAGREGHMLKVLSYISVRRLTPAPAIIFYGI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 IATIYIIPGDINSLVNYFSFAAWLFYGLTILGLIVMRFTRKELERPIKVPVVIPVLMTLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IATIYIIPGDINSLVNYFSFAAWLFYGLTILGLIVMRFTRKELERPIKVPVVIPVLMTLI
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE4 SVFLVLAPIISKPTWEYLYCVLFILSGLLFYFLFVHYKFGWAQKISKPITMHLQMLMEVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SVFLVLAPIISKPTWEYLYCVLFILSGLLFYFLFVHYKFGWAQKISKPITMHLQMLMEVV
430 440 450 460 470 480
pF1KE4 PPEEDPE
:::::::
NP_001 PPEEDPE
>>NP_001119807 (OMIM: 220100,604144) B(0,+)-type amino a (487 aa)
initn: 3167 init1: 3167 opt: 3167 Z-score: 3935.6 bits: 737.7 E(85289): 1.8e-212
Smith-Waterman score: 3167; 100.0% identity (100.0% similar) in 487 aa overlap (1-487:1-487)
10 20 30 40 50 60
pF1KE4 MGDTGLRKRREDEKSIQSQEPKTTSLQKELGLISGISIIVGTIIGSGIFVSPKSVLSNTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGDTGLRKRREDEKSIQSQEPKTTSLQKELGLISGISIIVGTIIGSGIFVSPKSVLSNTE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 AVGPCLIIWAACGVLATLGALCFAELGTMITKSGGEYPYLMEAYGPIPAYLFSWASLIVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AVGPCLIIWAACGVLATLGALCFAELGTMITKSGGEYPYLMEAYGPIPAYLFSWASLIVI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 KPTSFAIICLSFSEYVCAPFYVGCKPPQIVVKCLAAAAILFISTVNSLSVRLGSYVQNIF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KPTSFAIICLSFSEYVCAPFYVGCKPPQIVVKCLAAAAILFISTVNSLSVRLGSYVQNIF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 TAAKLVIVAIIIISGLVLLAQGNTKNFDNSFEGAQLSVGAISLAFYNGLWAYDGWNQLNY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TAAKLVIVAIIIISGLVLLAQGNTKNFDNSFEGAQLSVGAISLAFYNGLWAYDGWNQLNY
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 ITEELRNPYRNLPLAIIIGIPLVTACYILMNVSYFTVMTATELLQSQAVAVTFGDRVLYP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ITEELRNPYRNLPLAIIIGIPLVTACYILMNVSYFTVMTATELLQSQAVAVTFGDRVLYP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 ASWIVPLFVAFSTIGAANGTCFTAGRLIYVAGREGHMLKVLSYISVRRLTPAPAIIFYGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ASWIVPLFVAFSTIGAANGTCFTAGRLIYVAGREGHMLKVLSYISVRRLTPAPAIIFYGI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 IATIYIIPGDINSLVNYFSFAAWLFYGLTILGLIVMRFTRKELERPIKVPVVIPVLMTLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IATIYIIPGDINSLVNYFSFAAWLFYGLTILGLIVMRFTRKELERPIKVPVVIPVLMTLI
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE4 SVFLVLAPIISKPTWEYLYCVLFILSGLLFYFLFVHYKFGWAQKISKPITMHLQMLMEVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SVFLVLAPIISKPTWEYLYCVLFILSGLLFYFLFVHYKFGWAQKISKPITMHLQMLMEVV
430 440 450 460 470 480
pF1KE4 PPEEDPE
:::::::
NP_001 PPEEDPE
>>XP_011524704 (OMIM: 220100,604144) PREDICTED: B(0,+)-t (487 aa)
initn: 3167 init1: 3167 opt: 3167 Z-score: 3935.6 bits: 737.7 E(85289): 1.8e-212
Smith-Waterman score: 3167; 100.0% identity (100.0% similar) in 487 aa overlap (1-487:1-487)
10 20 30 40 50 60
pF1KE4 MGDTGLRKRREDEKSIQSQEPKTTSLQKELGLISGISIIVGTIIGSGIFVSPKSVLSNTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MGDTGLRKRREDEKSIQSQEPKTTSLQKELGLISGISIIVGTIIGSGIFVSPKSVLSNTE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 AVGPCLIIWAACGVLATLGALCFAELGTMITKSGGEYPYLMEAYGPIPAYLFSWASLIVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AVGPCLIIWAACGVLATLGALCFAELGTMITKSGGEYPYLMEAYGPIPAYLFSWASLIVI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 KPTSFAIICLSFSEYVCAPFYVGCKPPQIVVKCLAAAAILFISTVNSLSVRLGSYVQNIF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KPTSFAIICLSFSEYVCAPFYVGCKPPQIVVKCLAAAAILFISTVNSLSVRLGSYVQNIF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 TAAKLVIVAIIIISGLVLLAQGNTKNFDNSFEGAQLSVGAISLAFYNGLWAYDGWNQLNY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TAAKLVIVAIIIISGLVLLAQGNTKNFDNSFEGAQLSVGAISLAFYNGLWAYDGWNQLNY
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 ITEELRNPYRNLPLAIIIGIPLVTACYILMNVSYFTVMTATELLQSQAVAVTFGDRVLYP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ITEELRNPYRNLPLAIIIGIPLVTACYILMNVSYFTVMTATELLQSQAVAVTFGDRVLYP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 ASWIVPLFVAFSTIGAANGTCFTAGRLIYVAGREGHMLKVLSYISVRRLTPAPAIIFYGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ASWIVPLFVAFSTIGAANGTCFTAGRLIYVAGREGHMLKVLSYISVRRLTPAPAIIFYGI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 IATIYIIPGDINSLVNYFSFAAWLFYGLTILGLIVMRFTRKELERPIKVPVVIPVLMTLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IATIYIIPGDINSLVNYFSFAAWLFYGLTILGLIVMRFTRKELERPIKVPVVIPVLMTLI
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE4 SVFLVLAPIISKPTWEYLYCVLFILSGLLFYFLFVHYKFGWAQKISKPITMHLQMLMEVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SVFLVLAPIISKPTWEYLYCVLFILSGLLFYFLFVHYKFGWAQKISKPITMHLQMLMEVV
430 440 450 460 470 480
pF1KE4 PPEEDPE
:::::::
XP_011 PPEEDPE
>>XP_016881719 (OMIM: 220100,604144) PREDICTED: B(0,+)-t (399 aa)
initn: 2606 init1: 2606 opt: 2606 Z-score: 3239.8 bits: 608.6 E(85289): 1e-173
Smith-Waterman score: 2606; 100.0% identity (100.0% similar) in 399 aa overlap (89-487:1-399)
60 70 80 90 100 110
pF1KE4 TEAVGPCLIIWAACGVLATLGALCFAELGTMITKSGGEYPYLMEAYGPIPAYLFSWASLI
::::::::::::::::::::::::::::::
XP_016 MITKSGGEYPYLMEAYGPIPAYLFSWASLI
10 20 30
120 130 140 150 160 170
pF1KE4 VIKPTSFAIICLSFSEYVCAPFYVGCKPPQIVVKCLAAAAILFISTVNSLSVRLGSYVQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VIKPTSFAIICLSFSEYVCAPFYVGCKPPQIVVKCLAAAAILFISTVNSLSVRLGSYVQN
40 50 60 70 80 90
180 190 200 210 220 230
pF1KE4 IFTAAKLVIVAIIIISGLVLLAQGNTKNFDNSFEGAQLSVGAISLAFYNGLWAYDGWNQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IFTAAKLVIVAIIIISGLVLLAQGNTKNFDNSFEGAQLSVGAISLAFYNGLWAYDGWNQL
100 110 120 130 140 150
240 250 260 270 280 290
pF1KE4 NYITEELRNPYRNLPLAIIIGIPLVTACYILMNVSYFTVMTATELLQSQAVAVTFGDRVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NYITEELRNPYRNLPLAIIIGIPLVTACYILMNVSYFTVMTATELLQSQAVAVTFGDRVL
160 170 180 190 200 210
300 310 320 330 340 350
pF1KE4 YPASWIVPLFVAFSTIGAANGTCFTAGRLIYVAGREGHMLKVLSYISVRRLTPAPAIIFY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YPASWIVPLFVAFSTIGAANGTCFTAGRLIYVAGREGHMLKVLSYISVRRLTPAPAIIFY
220 230 240 250 260 270
360 370 380 390 400 410
pF1KE4 GIIATIYIIPGDINSLVNYFSFAAWLFYGLTILGLIVMRFTRKELERPIKVPVVIPVLMT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GIIATIYIIPGDINSLVNYFSFAAWLFYGLTILGLIVMRFTRKELERPIKVPVVIPVLMT
280 290 300 310 320 330
420 430 440 450 460 470
pF1KE4 LISVFLVLAPIISKPTWEYLYCVLFILSGLLFYFLFVHYKFGWAQKISKPITMHLQMLME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LISVFLVLAPIISKPTWEYLYCVLFILSGLLFYFLFVHYKFGWAQKISKPITMHLQMLME
340 350 360 370 380 390
480
pF1KE4 VVPPEEDPE
:::::::::
XP_016 VVPPEEDPE
>>XP_006723055 (OMIM: 220100,604144) PREDICTED: B(0,+)-t (260 aa)
initn: 1645 init1: 1645 opt: 1645 Z-score: 2048.3 bits: 387.5 E(85289): 2.4e-107
Smith-Waterman score: 1645; 100.0% identity (100.0% similar) in 252 aa overlap (236-487:9-260)
210 220 230 240 250 260
pF1KE4 NFDNSFEGAQLSVGAISLAFYNGLWAYDGWNQLNYITEELRNPYRNLPLAIIIGIPLVTA
::::::::::::::::::::::::::::::
XP_006 MPGRRRHLNQLNYITEELRNPYRNLPLAIIIGIPLVTA
10 20 30
270 280 290 300 310 320
pF1KE4 CYILMNVSYFTVMTATELLQSQAVAVTFGDRVLYPASWIVPLFVAFSTIGAANGTCFTAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 CYILMNVSYFTVMTATELLQSQAVAVTFGDRVLYPASWIVPLFVAFSTIGAANGTCFTAG
40 50 60 70 80 90
330 340 350 360 370 380
pF1KE4 RLIYVAGREGHMLKVLSYISVRRLTPAPAIIFYGIIATIYIIPGDINSLVNYFSFAAWLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RLIYVAGREGHMLKVLSYISVRRLTPAPAIIFYGIIATIYIIPGDINSLVNYFSFAAWLF
100 110 120 130 140 150
390 400 410 420 430 440
pF1KE4 YGLTILGLIVMRFTRKELERPIKVPVVIPVLMTLISVFLVLAPIISKPTWEYLYCVLFIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YGLTILGLIVMRFTRKELERPIKVPVVIPVLMTLISVFLVLAPIISKPTWEYLYCVLFIL
160 170 180 190 200 210
450 460 470 480
pF1KE4 SGLLFYFLFVHYKFGWAQKISKPITMHLQMLMEVVPPEEDPE
::::::::::::::::::::::::::::::::::::::::::
XP_006 SGLLFYFLFVHYKFGWAQKISKPITMHLQMLMEVVPPEEDPE
220 230 240 250 260
>>NP_055146 (OMIM: 607933) cystine/glutamate transporter (501 aa)
initn: 1330 init1: 1330 opt: 1404 Z-score: 1745.0 bits: 332.4 E(85289): 1.8e-90
Smith-Waterman score: 1404; 44.5% identity (76.1% similar) in 476 aa overlap (15-485:26-499)
10 20 30 40
pF1KE4 MGDTGLRKRREDEKSIQSQEP---KTTSLQKELGLISGISIIVGTIIGS
:. ..:: . ..:.... :. :.:::.:::::.
NP_055 MVRKPVVSTISKGGYLQGNVNGRLPSLGNKEPPGQEKVQLKRKVTLLRGVSIIIGTIIGA
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE4 GIFVSPKSVLSNTEAVGPCLIIWAACGVLATLGALCFAELGTMITKSGGEYPYLMEAYGP
:::.:::.::.:: .:: : ::..::::. .::: .::::: : ::::.: :..:..::
NP_055 GIFISPKGVLQNTGSVGMSLTIWTVCGVLSLFGALSYAELGTTIKKSGGHYTYILEVFGP
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE4 IPAYLFSWASLIVIKPTSFAIICLSFSEYVCAPFYVGCKPPQIVVKCLAAAAILFISTVN
.::.. :. :..:.:.. :.: :.:..:. ::.. :. :....: ..:..: . ..:
NP_055 LPAFVRVWVELLIIRPAATAVISLAFGRYILEPFFIQCEIPELAIKLITAVGITVVMVLN
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE4 SLSVRLGSYVQNIFTAAKLVIVAIIIISGLVLLAQGNTKNFDNSFEGAQLSVGAISLAFY
:.:: .. .: ..: ::. . :::. :.. : .:.:.:: ..: : . :. . ::::
NP_055 SMSVSWSARIQIFLTFCKLTAILIIIVPGVMQLIKGQTQNFKDAFSGRDSSITRLPLAFY
190 200 210 220 230 240
230 240 250 260 270 280
pF1KE4 NGLWAYDGWNQLNYITEELRNPYRNLPLAIIIGIPLVTACYILMNVSYFTVMTATELLQS
:..:: :: ::..:::..:: ...:::: :.. .:: :.: ::.:::...: ::: :
NP_055 YGMYAYAGWFYLNFVTEEVENPEKTIPLAICISMAIVTIGYVLTNVAYFTTINAEELLLS
250 260 270 280 290 300
290 300 310 320 330 340
pF1KE4 QAVAVTFGDRVLYPASWIVPLFVAFSTIGAANGTCFTAGRLIYVAGREGHMLKVLSYISV
.::::::..:.: : ::.:::.: .:. :: :...::.:::.::::. ..::.: :
NP_055 NAVAVTFSERLLGNFSLAVPIFVALSCFGSMNGGVFAVSRLFYVASREGHLPEILSMIHV
310 320 330 340 350 360
350 360 370 380 390 400
pF1KE4 RRLTPAPAIIFYGIIATIYIIPGDINSLVNYFSFAAWLFYGLTILGLIVMRFTRKELERP
:. :: ::.: .. :... ::..::.:..::: ::: ::.. ::: .:. ...::
NP_055 RKHTPLPAVIVLHPLTMIMLFSGDLDSLLNFLSFARWLFIGLAVAGLIYLRYKCPDMHRP
370 380 390 400 410 420
410 420 430 440 450 460
pF1KE4 IKVPVVIPVLMTLISVFLVLAPIISKPTWEYLYCVLFILSGLLFYFLFVHY--KFGWAQK
.:::. ::.:... .:.: . : : . :. :.:. :.::. . : : .
NP_055 FKVPLFIPALFSFTCLFMVALSLYSDPFSTGIGFVI-TLTGVPAYYLFIIWDKKPRWFRI
430 440 450 460 470
470 480
pF1KE4 ISKPITMHLQMLMEVVPPEEDPE
.:. :: ::...:::: :::
NP_055 MSEKITRTLQIILEVVP-EEDKL
480 490 500
>>NP_003477 (OMIM: 600182) large neutral amino acids tra (507 aa)
initn: 1407 init1: 754 opt: 1396 Z-score: 1735.0 bits: 330.5 E(85289): 6.7e-90
Smith-Waterman score: 1396; 45.2% identity (75.5% similar) in 473 aa overlap (15-483:35-506)
10 20 30 40
pF1KE4 MGDTGLRKRREDEKSIQSQEPKTTSLQKELGLISGISIIVGTII
: . : . ..::... :..:..:::::::
NP_003 GPKRRALAAPAAEEKEEAREKMLAAKSADGSAPAGEGEGVTLQRNITLLNGVAIIVGTII
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE4 GSGIFVSPKSVLSNTEAVGPCLIIWAACGVLATLGALCFAELGTMITKSGGEYPYLMEAY
::::::.: .::... . : :..::::::.. .::::.::::: :.::::.: :..:.:
NP_003 GSGIFVTPTGVLKEAGSPGLALVVWAACGVFSIVGALCYAELGTTISKSGGDYAYMLEVY
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE4 GPIPAYLFSWASLIVIKPTSFAIICLSFSEYVCAPFYVGCKPPQIVVKCLAAAAILFIST
: .::.: : :..:.:.: :. : :. :. :.. : :. ..: .: .:....
NP_003 GSLPAFLKLWIELLIIRPSSQYIVALVFATYLLKPLFPTCPVPEEAAKLVACLCVLLLTA
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE4 VNSLSVRLGSYVQNIFTAAKLVIVAIIIISGLVLLAQGNTKNFDN--SFEGAQLSVGAIS
:: ::. .. ::. :.::::. .:.::. :.: ...:...:.: ::::..:.:: :
NP_003 VNCYSVKAATRVQDAFAAAKLLALALIILLGFVQIGKGDVSNLDPNFSFEGTKLDVGNIV
190 200 210 220 230 240
230 240 250 260 270 280
pF1KE4 LAFYNGLWAYDGWNQLNYITEELRNPYRNLPLAIIIGIPLVTACYILMNVSYFTVMTATE
::.:.::.:: ::: ::..:::. ::::::::::::..:.:: :.: :..:::.... .
NP_003 LALYSGLFAYGGWNYLNFVTEEMINPYRNLPLAIIISLPIVTLVYVLTNLAYFTTLSTEQ
250 260 270 280 290 300
290 300 310 320 330 340
pF1KE4 LLQSQAVAVTFGDRVLYPASWIVPLFVAFSTIGAANGTCFTAGRLIYVAGREGHMLKVLS
.:.:.:::: ::. : :::.:.::..: .:..::. ::..::..:..::::. ..::
NP_003 MLSSEAVAVDFGNYHLGVMSWIIPVFVGLSCFGSVNGSLFTSSRLFFVGSREGHLPSILS
310 320 330 340 350 360
350 360 370 380 390 400
pF1KE4 YISVRRLTPAPAIIFYGIIATIYIIPGDINSLVNYFSFAAWLFYGLTILGLIVMRFTRKE
.: . :::.:...: ... .: . :: :..:.::: :: .:.:.:.: .: . :
NP_003 MIHPQLLTPVPSLVFTCVMTLLYAFSKDIFSVINFFSFFNWLCVALAIIGMIWLRHRKPE
370 380 390 400 410 420
410 420 430 440 450 460
pF1KE4 LERPIKVPVVIPVLMTLISVFLVLAPIISKPTWEYLYCVLFILSGLLFYFLFVHYKFG--
::::::: ...::.. : .::. . . . :. : .::::: ::. : .:
NP_003 LERPIKVNLALPVFFILACLFLIAVSFWKTPV-ECGIGFTIILSGLPVYFFGVWWKNKPK
430 440 450 460 470 480
470 480
pF1KE4 WAQKISKPITMHLQMLMEVVPPEEDPE
: . :. : ::.::: :
NP_003 WLLQGIFSTTVLCQKLMQVVPQET
490 500
>>XP_016879224 (OMIM: 600182) PREDICTED: large neutral a (509 aa)
initn: 1382 init1: 754 opt: 1373 Z-score: 1706.4 bits: 325.2 E(85289): 2.6e-88
Smith-Waterman score: 1373; 44.8% identity (75.9% similar) in 469 aa overlap (15-481:35-501)
10 20 30 40
pF1KE4 MGDTGLRKRREDEKSIQSQEPKTTSLQKELGLISGISIIVGTII
: . : . ..::... :..:..:::::::
XP_016 GPKRRALAAPAAEEKEEAREKMLAAKSADGSAPAGEGEGVTLQRNITLLNGVAIIVGTII
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE4 GSGIFVSPKSVLSNTEAVGPCLIIWAACGVLATLGALCFAELGTMITKSGGEYPYLMEAY
::::::.: .::... . : :..::::::.. .::::.::::: :.::::.: :..:.:
XP_016 GSGIFVTPTGVLKEAGSPGLALVVWAACGVFSIVGALCYAELGTTISKSGGDYAYMLEVY
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE4 GPIPAYLFSWASLIVIKPTSFAIICLSFSEYVCAPFYVGCKPPQIVVKCLAAAAILFIST
: .::.: : :..:.:.: :. : :. :. :.. : :. ..: .: .:....
XP_016 GSLPAFLKLWIELLIIRPSSQYIVALVFATYLLKPLFPTCPVPEEAAKLVACLCVLLLTA
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE4 VNSLSVRLGSYVQNIFTAAKLVIVAIIIISGLVLLAQGNTKNFDN--SFEGAQLSVGAIS
:: ::. .. ::. :.::::. .:.::. :.: ...:...:.: ::::..:.:: :
XP_016 VNCYSVKAATRVQDAFAAAKLLALALIILLGFVQIGKGDVSNLDPNFSFEGTKLDVGNIV
190 200 210 220 230 240
230 240 250 260 270 280
pF1KE4 LAFYNGLWAYDGWNQLNYITEELRNPYRNLPLAIIIGIPLVTACYILMNVSYFTVMTATE
::.:.::.:: ::: ::..:::. ::::::::::::..:.:: :.: :..:::.... .
XP_016 LALYSGLFAYGGWNYLNFVTEEMINPYRNLPLAIIISLPIVTLVYVLTNLAYFTTLSTEQ
250 260 270 280 290 300
290 300 310 320 330 340
pF1KE4 LLQSQAVAVTFGDRVLYPASWIVPLFVAFSTIGAANGTCFTAGRLIYVAGREGHMLKVLS
.:.:.:::: ::. : :::.:.::..: .:..::. ::..::..:..::::. ..::
XP_016 MLSSEAVAVDFGNYHLGVMSWIIPVFVGLSCFGSVNGSLFTSSRLFFVGSREGHLPSILS
310 320 330 340 350 360
350 360 370 380 390 400
pF1KE4 YISVRRLTPAPAIIFYGIIATIYIIPGDINSLVNYFSFAAWLFYGLTILGLIVMRFTRKE
.: . :::.:...: ... .: . :: :..:.::: :: .:.:.:.: .: . :
XP_016 MIHPQLLTPVPSLVFTCVMTLLYAFSKDIFSVINFFSFFNWLCVALAIIGMIWLRHRKPE
370 380 390 400 410 420
410 420 430 440 450 460
pF1KE4 LERPIKVPVVIPVLMTLISVFLVLAPIISKPTWEYLYCVLFILSGLLFYFLFVHYKFGWA
::::::: ...::.. : .::. . . . :. : .::::: ::. : .: .
XP_016 LERPIKVNLALPVFFILACLFLIAVSFWKTPV-ECGIGFTIILSGLPVYFFGVWWK-NKP
430 440 450 460 470 480
470 480
pF1KE4 QKISKPITMHLQMLMEVVPPEEDPE
. . . : .: . :::
XP_016 KWLLQGICEYLAGPQPVVPSALGSEGS
490 500
>>XP_006720365 (OMIM: 222700,603593) PREDICTED: Y+L amin (511 aa)
initn: 1353 init1: 1286 opt: 1367 Z-score: 1699.0 bits: 323.9 E(85289): 6.8e-88
Smith-Waterman score: 1367; 43.9% identity (75.3% similar) in 474 aa overlap (18-487:25-497)
10 20 30 40 50
pF1KE4 MGDTGLRKRREDEKSIQSQEPKTTSLQKELGLISGISIIVGTIIGSGIFVSPK
: :. ..:.::..:..:. .:::..::::::::::
XP_006 MVDSTEYEVASQPEVETSPLGDGASPGPEQVKLKKEISLLNGVCLIVGNMIGSGIFVSPK
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE4 SVLSNTEAVGPCLIIWAACGVLATLGALCFAELGTMITKSGGEYPYLMEAYGPIPAYLFS
.:: . . : :.:::. :.....::::.::::: : :::. : :..::.: . :..
XP_006 GVLIYSASFGLSLVIWAVGGLFSVFGALCYAELGTTIKKSGASYAYILEAFGGFLAFIRL
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE4 WASLIVIKPTSFAIICLSFSEYVCAPFYVGCKPPQIVVKCLAAAAILFISTVNSLSVRLG
:.::..:.::: ::: ..:..:. :.. .: : . . :::: : ... .: :. :
XP_006 WTSLLIIEPTSQAIIAITFANYMVQPLFPSCFAPYAASRLLAAACICLLTFINCAYVKWG
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE4 SYVQNIFTAAKLVIVAIIIISGLVLLAQGNTKNFDNSFEGAQLSVGAISLAFYNGLWAYD
. ::.::: ::.. . .:..:.: :.:: . .:.:::::....:: :.::.:..:..:.
XP_006 TLVQDIFTYAKVLALIAVIVAGIVRLGQGASTHFENSFEGSSFAVGDIALALYSALFSYS
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE4 GWNQLNYITEELRNPYRNLPLAIIIGIPLVTACYILMNVSYFTVMTATELLQSQAVAVTF
::. :::.:::..:: :::::.: :..:.:: ::: ::.:.::. ..: :.::::::
XP_006 GWDTLNYVTEEIKNPERNLPLSIGISMPIVTIIYILTNVAYYTVLDMRDILASDAVAVTF
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE4 GDRVLYPASWIVPLFVAFSTIGAANGTCFTAGRLIYVAGREGHMLKVLSYISVRRLTPAP
.:... .::.:: ::.: .:. :.. .:.::..:..::::. .. .: :.:.::.:
XP_006 ADQIFGIFNWIIPLSVALSCFGGLNASIVAASRLFFVGSREGHLPDAICMIHVERFTPVP
310 320 330 340 350 360
360 370 380 390 400 410
pF1KE4 AIIFYGIIATIYIIPGDINSLVNYFSFAAWLFYGLTILGLIVMRFTRKELERPIKVPVVI
...: ::.: ::. :: .:.::.::. :.: ::.:.: . .:. . . ::.:. : .
XP_006 SLLFNGIMALIYLCVEDIFQLINYYSFSYWFFVGLSIVGQLYLRWKEPDRPRPLKLSVFF
370 380 390 400 410 420
420 430 440 450 460
pF1KE4 PVLMTLISVFLVLAPIISKPTWEYLYCVLFILSGLLFYFLFV----HYKFGWAQKISKPI
:... : ..::: .:. : : . : . . :::: ::::.. : . . ..:
XP_006 PIVFCLCTIFLVAVPLYSD-TINSLIGIAIALSGLPFYFLIIRVPEHKRPLYLRRIVGSA
430 440 450 460 470
470 480
pF1KE4 TMHLQMLMEVVPPEEDPE
: .::.: : : : :
XP_006 TRYLQVLCMSVAAEMDLEDGGEMPKQRDPKSN
480 490 500 510
487 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 00:55:54 2016 done: Sun Nov 6 00:55:55 2016
Total Scan time: 8.550 Total Display time: 0.100
Function used was FASTA [36.3.4 Apr, 2011]