Result of FASTA (ccds) for
pFN21AE4456
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE4456, 475 aa
1>>>pF1KE4456 475 - 475 aa - 475 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.9973+/-0.00107; mu= 13.7120+/- 0.064
mean_var=63.1739+/-12.606, 0's: 0 Z-trim(102.7): 25 B-trim: 0 in 0/49
Lambda= 0.161364
statistics sampled from 7047 (7064) to 7047 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.582), E-opt: 0.2 (0.217), width: 16
Scan time: 2.070
The best scores are: opt bits E(32554)
CCDS1722.1 HADHB gene_id:3032|Hs108|chr2 ( 474) 3068 723.2 1.4e-208
CCDS62872.1 HADHB gene_id:3032|Hs108|chr2 ( 452) 2834 668.8 3.3e-192
CCDS62871.1 HADHB gene_id:3032|Hs108|chr2 ( 459) 2531 598.2 5.8e-171
CCDS8339.1 ACAT1 gene_id:38|Hs108|chr11 ( 427) 257 68.8 1.2e-11
>>CCDS1722.1 HADHB gene_id:3032|Hs108|chr2 (474 aa)
initn: 3068 init1: 3068 opt: 3068 Z-score: 3858.2 bits: 723.2 E(32554): 1.4e-208
Smith-Waterman score: 3068; 100.0% identity (100.0% similar) in 473 aa overlap (3-475:2-474)
10 20 30 40 50 60
pF1KE4 MTTILTYPFKNLPTASKWALRFSIRPLSCSSQLRAAPAVQTKTKKTLAKPNIRNVVVVDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS17 MTILTYPFKNLPTASKWALRFSIRPLSCSSQLRAAPAVQTKTKKTLAKPNIRNVVVVDG
10 20 30 40 50
70 80 90 100 110 120
pF1KE4 VRTPFLLSGTSYKDLMPHDLARAALTGLLHRTSVPKEVVDYIIFGTVIQEVKTSNVAREA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS17 VRTPFLLSGTSYKDLMPHDLARAALTGLLHRTSVPKEVVDYIIFGTVIQEVKTSNVAREA
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE4 ALGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVELMSDVPIRHSRKM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS17 ALGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVELMSDVPIRHSRKM
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE4 RKLMLDLNKAKSMGQRLSLISKFRFNFLAPELPAVSEFSTSETMGHSADRLAAAFAVSRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS17 RKLMLDLNKAKSMGQRLSLISKFRFNFLAPELPAVSEFSTSETMGHSADRLAAAFAVSRL
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE4 EQDEYALRSHSLAKKAQDEGLLSDVVPFKVPGKDTVTKDNGIRPSSLEQMAKLKPAFIKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS17 EQDEYALRSHSLAKKAQDEGLLSDVVPFKVPGKDTVTKDNGIRPSSLEQMAKLKPAFIKP
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE4 YGTVTAANSSFLTDGASAMLIMAEEKALAMGYKPKAYLRDFMYVSQDPKDQLLLGPTYAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS17 YGTVTAANSSFLTDGASAMLIMAEEKALAMGYKPKAYLRDFMYVSQDPKDQLLLGPTYAT
300 310 320 330 340 350
370 380 390 400 410 420
pF1KE4 PKVLEKAGLTMNDIDAFEFHEAFSGQILANFKAMDSDWFAENYMGRKTKVGLPPLEKFNN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS17 PKVLEKAGLTMNDIDAFEFHEAFSGQILANFKAMDSDWFAENYMGRKTKVGLPPLEKFNN
360 370 380 390 400 410
430 440 450 460 470
pF1KE4 WGGSLSLGHPFGATGCRLVMAAANRLRKEGGQYGLVAACAAGGQGHAMIVEAYPK
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS17 WGGSLSLGHPFGATGCRLVMAAANRLRKEGGQYGLVAACAAGGQGHAMIVEAYPK
420 430 440 450 460 470
>>CCDS62872.1 HADHB gene_id:3032|Hs108|chr2 (452 aa)
initn: 2834 init1: 2834 opt: 2834 Z-score: 3564.1 bits: 668.8 E(32554): 3.3e-192
Smith-Waterman score: 2834; 100.0% identity (100.0% similar) in 438 aa overlap (38-475:15-452)
10 20 30 40 50 60
pF1KE4 PFKNLPTASKWALRFSIRPLSCSSQLRAAPAVQTKTKKTLAKPNIRNVVVVDGVRTPFLL
::::::::::::::::::::::::::::::
CCDS62 MTLVSGWLLYGWIIAVQTKTKKTLAKPNIRNVVVVDGVRTPFLL
10 20 30 40
70 80 90 100 110 120
pF1KE4 SGTSYKDLMPHDLARAALTGLLHRTSVPKEVVDYIIFGTVIQEVKTSNVAREAALGAGFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS62 SGTSYKDLMPHDLARAALTGLLHRTSVPKEVVDYIIFGTVIQEVKTSNVAREAALGAGFS
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE4 DKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVELMSDVPIRHSRKMRKLMLDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS62 DKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVELMSDVPIRHSRKMRKLMLDL
110 120 130 140 150 160
190 200 210 220 230 240
pF1KE4 NKAKSMGQRLSLISKFRFNFLAPELPAVSEFSTSETMGHSADRLAAAFAVSRLEQDEYAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS62 NKAKSMGQRLSLISKFRFNFLAPELPAVSEFSTSETMGHSADRLAAAFAVSRLEQDEYAL
170 180 190 200 210 220
250 260 270 280 290 300
pF1KE4 RSHSLAKKAQDEGLLSDVVPFKVPGKDTVTKDNGIRPSSLEQMAKLKPAFIKPYGTVTAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS62 RSHSLAKKAQDEGLLSDVVPFKVPGKDTVTKDNGIRPSSLEQMAKLKPAFIKPYGTVTAA
230 240 250 260 270 280
310 320 330 340 350 360
pF1KE4 NSSFLTDGASAMLIMAEEKALAMGYKPKAYLRDFMYVSQDPKDQLLLGPTYATPKVLEKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS62 NSSFLTDGASAMLIMAEEKALAMGYKPKAYLRDFMYVSQDPKDQLLLGPTYATPKVLEKA
290 300 310 320 330 340
370 380 390 400 410 420
pF1KE4 GLTMNDIDAFEFHEAFSGQILANFKAMDSDWFAENYMGRKTKVGLPPLEKFNNWGGSLSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS62 GLTMNDIDAFEFHEAFSGQILANFKAMDSDWFAENYMGRKTKVGLPPLEKFNNWGGSLSL
350 360 370 380 390 400
430 440 450 460 470
pF1KE4 GHPFGATGCRLVMAAANRLRKEGGQYGLVAACAAGGQGHAMIVEAYPK
::::::::::::::::::::::::::::::::::::::::::::::::
CCDS62 GHPFGATGCRLVMAAANRLRKEGGQYGLVAACAAGGQGHAMIVEAYPK
410 420 430 440 450
>>CCDS62871.1 HADHB gene_id:3032|Hs108|chr2 (459 aa)
initn: 2531 init1: 2531 opt: 2531 Z-score: 3182.8 bits: 598.2 E(32554): 5.8e-171
Smith-Waterman score: 2929; 96.8% identity (96.8% similar) in 473 aa overlap (3-475:2-459)
10 20 30 40 50 60
pF1KE4 MTTILTYPFKNLPTASKWALRFSIRPLSCSSQLRAAPAVQTKTKKTLAKPNIRNVVVVDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS62 MTILTYPFKNLPTASKWALRFSIRPLSCSSQLRAAPAVQTKTKKTLAKPNIRNVVVVDG
10 20 30 40 50
70 80 90 100 110 120
pF1KE4 VRTPFLLSGTSYKDLMPHDLARAALTGLLHRTSVPKEVVDYIIFGTVIQEVKTSNVAREA
::::::::::: ::::::::::::::::::::::::::::::::::
CCDS62 VRTPFLLSGTS---------------GLLHRTSVPKEVVDYIIFGTVIQEVKTSNVAREA
60 70 80 90 100
130 140 150 160 170 180
pF1KE4 ALGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVELMSDVPIRHSRKM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS62 ALGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVELMSDVPIRHSRKM
110 120 130 140 150 160
190 200 210 220 230 240
pF1KE4 RKLMLDLNKAKSMGQRLSLISKFRFNFLAPELPAVSEFSTSETMGHSADRLAAAFAVSRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS62 RKLMLDLNKAKSMGQRLSLISKFRFNFLAPELPAVSEFSTSETMGHSADRLAAAFAVSRL
170 180 190 200 210 220
250 260 270 280 290 300
pF1KE4 EQDEYALRSHSLAKKAQDEGLLSDVVPFKVPGKDTVTKDNGIRPSSLEQMAKLKPAFIKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS62 EQDEYALRSHSLAKKAQDEGLLSDVVPFKVPGKDTVTKDNGIRPSSLEQMAKLKPAFIKP
230 240 250 260 270 280
310 320 330 340 350 360
pF1KE4 YGTVTAANSSFLTDGASAMLIMAEEKALAMGYKPKAYLRDFMYVSQDPKDQLLLGPTYAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS62 YGTVTAANSSFLTDGASAMLIMAEEKALAMGYKPKAYLRDFMYVSQDPKDQLLLGPTYAT
290 300 310 320 330 340
370 380 390 400 410 420
pF1KE4 PKVLEKAGLTMNDIDAFEFHEAFSGQILANFKAMDSDWFAENYMGRKTKVGLPPLEKFNN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS62 PKVLEKAGLTMNDIDAFEFHEAFSGQILANFKAMDSDWFAENYMGRKTKVGLPPLEKFNN
350 360 370 380 390 400
430 440 450 460 470
pF1KE4 WGGSLSLGHPFGATGCRLVMAAANRLRKEGGQYGLVAACAAGGQGHAMIVEAYPK
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS62 WGGSLSLGHPFGATGCRLVMAAANRLRKEGGQYGLVAACAAGGQGHAMIVEAYPK
410 420 430 440 450
>>CCDS8339.1 ACAT1 gene_id:38|Hs108|chr11 (427 aa)
initn: 640 init1: 250 opt: 257 Z-score: 322.3 bits: 68.8 E(32554): 1.2e-11
Smith-Waterman score: 649; 31.9% identity (60.9% similar) in 445 aa overlap (34-471:21-425)
10 20 30 40 50 60
pF1KE4 ILTYPFKNLPTASKWALRFSIRPLSCSSQLRAAPAVQTKTKKTLAKPNIRNVVVVDGVRT
: . .. .. ..::....::.:...::
CCDS83 MAVLAALLRSGARSRSPLLRRLVQEIRYVERSYVSKPTLKEVVIVSATRT
10 20 30 40 50
70 80 90 100 110 120
pF1KE4 PFLLSGTSYKDLMPHD-LARAALTGLLHRTSVPKEVVDYIIFGTVIQEVKTSNVAREAAL
: . : . .:.: :. :. : ......::: : .:.:.: . . .:.:.:
CCDS83 P-IGSFLGSLSLLPATKLGSIAIQGAIEKAGIPKEEVKEAYMGNVLQGGEGQAPTRQAVL
60 70 80 90 100
130 140 150 160 170 180
pF1KE4 GAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVELMSDVPIRHSRKMRK
:::. .:: :.. .: :. .:. . . :. ::.::::.: ::.:: .:
CCDS83 GAGLPISTPCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGGMESMSNVPYVMNR----
110 120 130 140 150 160
190 200 210 220 230 240
pF1KE4 LMLDLNKAKSMGQRL-SLISKFRFNFLAPELPAVSEFSTSETMGHSADRLAAAFAVSRLE
... : .: .:: : .... .. :: :. : . ..: :
CCDS83 -----GSTPYGGVKLEDLIVK----------DGLTDVYNKIHMGSCAENTAKKLNIARNE
170 180 190 200 210
250 260 270 280 290
pF1KE4 QDEYALRSHSLAKKAQDEGLL-SDVVPFKVPGK---DTVTK-DNGIRPSSLEQMAKLKPA
:: ::. :.. .: : . : . ..:.: : : :.:.: :. . .. .. ::: .
CCDS83 QDAYAINSYTRSKAAWEAGKFGNEVIPVTVTVKGQPDVVVKEDEEYKRVDFSKVPKLKTV
220 230 240 250 260 270
300 310 320 330 340 350
pF1KE4 FIKPYGTVTAANSSFLTDGASAMLIMAEEKALAMGYKPKAYLRDFMYVSQDPKDQLLLGP
: : :::::::.: :.:::.:...:. . : .. : : . : .. .: : . ..:
CCDS83 FQKENGTVTAANASTLNDGAAALVLMTADAAKRLNVTPLARIVAFADAAVEPID-FPIAP
280 290 300 310 320
360 370 380 390 400 410
pF1KE4 TYATPKVLEKAGLTMNDIDAFEFHEAFSGQILANFKAMDSDWFAENYMGRKTKVGLPPLE
.::. ::. .:: .:: .: .:::: .:::.: .. : : .
CCDS83 VYAASMVLKDVGLKKEDIAMWEVNEAFSLVVLANIKMLEID---------------P--Q
330 340 350 360 370
420 430 440 450 460 470
pF1KE4 KFNNWGGSLSLGHPFGATGCRLVMAAANRLRKEGGQYGLVAACAAGGQGHAMIVEAYPK
: : ::..:::::.: .: :.: .. :.. :.:::.. : .:: . ::...
CCDS83 KVNINGGAVSLGHPIGMSGARIVGHLTHALKQ--GEYGLASICNGGGGASAMLIQKL
380 390 400 410 420
475 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 00:59:50 2016 done: Sun Nov 6 00:59:50 2016
Total Scan time: 2.070 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]