Result of FASTA (omim) for
pFN21AE4447
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE4447, 462 aa
1>>>pF1KE4447 462 - 462 aa - 462 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.2789+/-0.000433; mu= 12.2908+/- 0.027
mean_var=72.0166+/-14.758, 0's: 0 Z-trim(110.3): 161 B-trim: 323 in 1/51
Lambda= 0.151132
statistics sampled from 18499 (18678) to 18499 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.566), E-opt: 0.2 (0.219), width: 16
Scan time: 5.890
The best scores are: opt bits E(85289)
XP_006720522 (OMIM: 137142) PREDICTED: gamma-amino ( 462) 3042 672.9 4.9e-193
NP_000801 (OMIM: 137142) gamma-aminobutyric acid r ( 462) 3042 672.9 4.9e-193
NP_001158509 (OMIM: 137142) gamma-aminobutyric aci ( 462) 3042 672.9 4.9e-193
XP_005268315 (OMIM: 137142) PREDICTED: gamma-amino ( 462) 3042 672.9 4.9e-193
NP_001107647 (OMIM: 103780,137140) gamma-aminobuty ( 451) 2156 479.7 6.8e-135
XP_016863471 (OMIM: 103780,137140) PREDICTED: gamm ( 451) 2156 479.7 6.8e-135
XP_016863472 (OMIM: 103780,137140) PREDICTED: gamm ( 451) 2156 479.7 6.8e-135
NP_000798 (OMIM: 103780,137140) gamma-aminobutyric ( 451) 2156 479.7 6.8e-135
NP_001121116 (OMIM: 137160,611136,615744) gamma-am ( 456) 2113 470.4 4.6e-132
NP_000797 (OMIM: 137160,611136,615744) gamma-amino ( 456) 2113 470.4 4.6e-132
NP_001121115 (OMIM: 137160,611136,615744) gamma-am ( 456) 2113 470.4 4.6e-132
NP_001121120 (OMIM: 137160,611136,615744) gamma-am ( 456) 2113 470.4 4.6e-132
NP_001121117 (OMIM: 137160,611136,615744) gamma-am ( 456) 2113 470.4 4.6e-132
XP_016877545 (OMIM: 137142) PREDICTED: gamma-amino ( 306) 1962 437.4 2.6e-122
XP_016877544 (OMIM: 137142) PREDICTED: gamma-amino ( 306) 1962 437.4 2.6e-122
NP_000799 (OMIM: 305660) gamma-aminobutyric acid r ( 492) 1922 428.7 1.7e-119
XP_005248137 (OMIM: 103780,137140) PREDICTED: gamm ( 396) 1884 420.4 4.3e-117
NP_001317619 (OMIM: 103780,137140) gamma-aminobuty ( 511) 1861 415.4 1.8e-115
XP_011511977 (OMIM: 103780,137140) PREDICTED: gamm ( 511) 1861 415.4 1.8e-115
NP_001273756 (OMIM: 103780,137140) gamma-aminobuty ( 456) 1589 356.1 1.1e-97
NP_000802 (OMIM: 137143) gamma-aminobutyric acid r ( 453) 1575 353.1 9.4e-97
NP_000800 (OMIM: 137141) gamma-aminobutyric acid r ( 554) 1570 352.0 2.4e-96
NP_001191195 (OMIM: 137141) gamma-aminobutyric aci ( 535) 1569 351.8 2.7e-96
XP_006724874 (OMIM: 305660) PREDICTED: gamma-amino ( 340) 1466 329.3 1e-89
NP_775807 (OMIM: 137166) gamma-aminobutyric acid r ( 465) 1249 282.0 2.4e-75
NP_000807 (OMIM: 137164,607681,611277) gamma-amino ( 467) 1229 277.6 4.9e-74
NP_944494 (OMIM: 137164,607681,611277) gamma-amino ( 475) 1224 276.5 1.1e-73
NP_150092 (OMIM: 600233) gamma-aminobutyric acid r ( 467) 1124 254.7 3.9e-67
XP_011519732 (OMIM: 600233) PREDICTED: gamma-amino ( 473) 1121 254.1 6.1e-67
XP_016863479 (OMIM: 137166) PREDICTED: gamma-amino ( 336) 996 226.8 7.1e-59
NP_004952 (OMIM: 300093) gamma-aminobutyric acid r ( 506) 983 224.0 7.5e-58
NP_001191196 (OMIM: 137141) gamma-aminobutyric aci ( 484) 978 222.9 1.5e-57
XP_011543798 (OMIM: 305990) PREDICTED: glycine rec ( 436) 953 217.4 6e-56
XP_006724550 (OMIM: 305990) PREDICTED: glycine rec ( 436) 953 217.4 6e-56
XP_011543797 (OMIM: 305990) PREDICTED: glycine rec ( 436) 953 217.4 6e-56
NP_002054 (OMIM: 305990) glycine receptor subunit ( 452) 953 217.4 6.2e-56
NP_001112357 (OMIM: 305990) glycine receptor subun ( 452) 953 217.4 6.2e-56
NP_001112358 (OMIM: 305990) glycine receptor subun ( 452) 951 217.0 8.5e-56
XP_016884916 (OMIM: 305990) PREDICTED: glycine rec ( 452) 951 217.0 8.5e-56
NP_001036008 (OMIM: 600421) glycine receptor subun ( 449) 937 213.9 7e-55
XP_016864838 (OMIM: 138491,149400) PREDICTED: glyc ( 465) 937 213.9 7.2e-55
NP_000162 (OMIM: 138491,149400) glycine receptor s ( 449) 936 213.7 8.1e-55
NP_001139512 (OMIM: 138491,149400) glycine recepto ( 457) 921 210.5 8e-54
XP_016864119 (OMIM: 600421) PREDICTED: glycine rec ( 424) 901 206.1 1.5e-52
NP_006520 (OMIM: 600421) glycine receptor subunit ( 464) 901 206.1 1.7e-52
XP_016877548 (OMIM: 600233) PREDICTED: gamma-amino ( 355) 892 204.1 5e-52
XP_016877547 (OMIM: 600233) PREDICTED: gamma-amino ( 361) 889 203.5 8e-52
NP_068712 (OMIM: 137192,612269,617113) gamma-amino ( 473) 890 203.7 8.9e-52
NP_000805 (OMIM: 137192,612269,617113) gamma-amino ( 473) 877 200.9 6.4e-51
NP_000803 (OMIM: 137190,617153) gamma-aminobutyric ( 474) 865 198.3 3.9e-50
>>XP_006720522 (OMIM: 137142) PREDICTED: gamma-aminobuty (462 aa)
initn: 3042 init1: 3042 opt: 3042 Z-score: 3586.6 bits: 672.9 E(85289): 4.9e-193
Smith-Waterman score: 3042; 100.0% identity (100.0% similar) in 462 aa overlap (1-462:1-462)
10 20 30 40 50 60
pF1KE4 MDNGMFSGFIMIKNLLLFCISMNLSSHFGFSQMPTSSVKDETNDNITIFTRILDGLLDGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MDNGMFSGFIMIKNLLLFCISMNLSSHFGFSQMPTSSVKDETNDNITIFTRILDGLLDGY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 DNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQSWKDERLRFKGPMQRLPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQSWKDERLRFKGPMQRLPL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 NNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLYTMRLTISAECPMQLEDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLYTMRLTISAECPMQLEDF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 PMDAHACPLKFGSYAYPNSEVVYVWTNGSTKSVVVAEDGSRLNQYHLMGQTVGTENISTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PMDAHACPLKFGSYAYPNSEVVYVWTNGSTKSVVVAEDGSRLNQYHLMGQTVGTENISTS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 TGEYTIMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TGEYTIMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTM
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 TTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGWAWDGKKALEAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGWAWDGKKALEAA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 KIKKKREVILNKSTNAFTTGKMSHPPNIPKEQTPAGTSNTTSVSVKPSEEKTSESKKTYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KIKKKREVILNKSTNAFTTGKMSHPPNIPKEQTPAGTSNTTSVSVKPSEEKTSESKKTYN
370 380 390 400 410 420
430 440 450 460
pF1KE4 SISKIDKMSRIVFPVLFGTFNLVYWATYLNREPVIKGAASPK
::::::::::::::::::::::::::::::::::::::::::
XP_006 SISKIDKMSRIVFPVLFGTFNLVYWATYLNREPVIKGAASPK
430 440 450 460
>>NP_000801 (OMIM: 137142) gamma-aminobutyric acid recep (462 aa)
initn: 3042 init1: 3042 opt: 3042 Z-score: 3586.6 bits: 672.9 E(85289): 4.9e-193
Smith-Waterman score: 3042; 100.0% identity (100.0% similar) in 462 aa overlap (1-462:1-462)
10 20 30 40 50 60
pF1KE4 MDNGMFSGFIMIKNLLLFCISMNLSSHFGFSQMPTSSVKDETNDNITIFTRILDGLLDGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MDNGMFSGFIMIKNLLLFCISMNLSSHFGFSQMPTSSVKDETNDNITIFTRILDGLLDGY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 DNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQSWKDERLRFKGPMQRLPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 DNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQSWKDERLRFKGPMQRLPL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 NNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLYTMRLTISAECPMQLEDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 NNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLYTMRLTISAECPMQLEDF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 PMDAHACPLKFGSYAYPNSEVVYVWTNGSTKSVVVAEDGSRLNQYHLMGQTVGTENISTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 PMDAHACPLKFGSYAYPNSEVVYVWTNGSTKSVVVAEDGSRLNQYHLMGQTVGTENISTS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 TGEYTIMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 TGEYTIMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTM
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 TTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGWAWDGKKALEAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 TTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGWAWDGKKALEAA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 KIKKKREVILNKSTNAFTTGKMSHPPNIPKEQTPAGTSNTTSVSVKPSEEKTSESKKTYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 KIKKKREVILNKSTNAFTTGKMSHPPNIPKEQTPAGTSNTTSVSVKPSEEKTSESKKTYN
370 380 390 400 410 420
430 440 450 460
pF1KE4 SISKIDKMSRIVFPVLFGTFNLVYWATYLNREPVIKGAASPK
::::::::::::::::::::::::::::::::::::::::::
NP_000 SISKIDKMSRIVFPVLFGTFNLVYWATYLNREPVIKGAASPK
430 440 450 460
>>NP_001158509 (OMIM: 137142) gamma-aminobutyric acid re (462 aa)
initn: 3042 init1: 3042 opt: 3042 Z-score: 3586.6 bits: 672.9 E(85289): 4.9e-193
Smith-Waterman score: 3042; 100.0% identity (100.0% similar) in 462 aa overlap (1-462:1-462)
10 20 30 40 50 60
pF1KE4 MDNGMFSGFIMIKNLLLFCISMNLSSHFGFSQMPTSSVKDETNDNITIFTRILDGLLDGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDNGMFSGFIMIKNLLLFCISMNLSSHFGFSQMPTSSVKDETNDNITIFTRILDGLLDGY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 DNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQSWKDERLRFKGPMQRLPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQSWKDERLRFKGPMQRLPL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 NNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLYTMRLTISAECPMQLEDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLYTMRLTISAECPMQLEDF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 PMDAHACPLKFGSYAYPNSEVVYVWTNGSTKSVVVAEDGSRLNQYHLMGQTVGTENISTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PMDAHACPLKFGSYAYPNSEVVYVWTNGSTKSVVVAEDGSRLNQYHLMGQTVGTENISTS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 TGEYTIMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TGEYTIMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTM
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 TTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGWAWDGKKALEAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGWAWDGKKALEAA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 KIKKKREVILNKSTNAFTTGKMSHPPNIPKEQTPAGTSNTTSVSVKPSEEKTSESKKTYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KIKKKREVILNKSTNAFTTGKMSHPPNIPKEQTPAGTSNTTSVSVKPSEEKTSESKKTYN
370 380 390 400 410 420
430 440 450 460
pF1KE4 SISKIDKMSRIVFPVLFGTFNLVYWATYLNREPVIKGAASPK
::::::::::::::::::::::::::::::::::::::::::
NP_001 SISKIDKMSRIVFPVLFGTFNLVYWATYLNREPVIKGAASPK
430 440 450 460
>>XP_005268315 (OMIM: 137142) PREDICTED: gamma-aminobuty (462 aa)
initn: 3042 init1: 3042 opt: 3042 Z-score: 3586.6 bits: 672.9 E(85289): 4.9e-193
Smith-Waterman score: 3042; 100.0% identity (100.0% similar) in 462 aa overlap (1-462:1-462)
10 20 30 40 50 60
pF1KE4 MDNGMFSGFIMIKNLLLFCISMNLSSHFGFSQMPTSSVKDETNDNITIFTRILDGLLDGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MDNGMFSGFIMIKNLLLFCISMNLSSHFGFSQMPTSSVKDETNDNITIFTRILDGLLDGY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 DNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQSWKDERLRFKGPMQRLPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQSWKDERLRFKGPMQRLPL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 NNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLYTMRLTISAECPMQLEDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLYTMRLTISAECPMQLEDF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 PMDAHACPLKFGSYAYPNSEVVYVWTNGSTKSVVVAEDGSRLNQYHLMGQTVGTENISTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PMDAHACPLKFGSYAYPNSEVVYVWTNGSTKSVVVAEDGSRLNQYHLMGQTVGTENISTS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 TGEYTIMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TGEYTIMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTM
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 TTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGWAWDGKKALEAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGWAWDGKKALEAA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 KIKKKREVILNKSTNAFTTGKMSHPPNIPKEQTPAGTSNTTSVSVKPSEEKTSESKKTYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KIKKKREVILNKSTNAFTTGKMSHPPNIPKEQTPAGTSNTTSVSVKPSEEKTSESKKTYN
370 380 390 400 410 420
430 440 450 460
pF1KE4 SISKIDKMSRIVFPVLFGTFNLVYWATYLNREPVIKGAASPK
::::::::::::::::::::::::::::::::::::::::::
XP_005 SISKIDKMSRIVFPVLFGTFNLVYWATYLNREPVIKGAASPK
430 440 450 460
>>NP_001107647 (OMIM: 103780,137140) gamma-aminobutyric (451 aa)
initn: 2174 init1: 1875 opt: 2156 Z-score: 2542.7 bits: 479.7 E(85289): 6.8e-135
Smith-Waterman score: 2156; 76.5% identity (89.9% similar) in 425 aa overlap (39-461:32-451)
10 20 30 40 50 60
pF1KE4 FIMIKNLLLFCISMNLSSHFGFSQMPTSSVKDETNDNITIFTRILDGLLDGYDNRLRPGL
.::...:::::::::: :::::::::::::
NP_001 KTKLNIYNMQFLLFVFLVWDPARLVLANIQEDEAKNNITIFTRILDRLLDGYDNRLRPGL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 GERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQSWKDERLRFKGPMQRLPLNNLLASKI
:. ::.: :.::::::::::::.:::::::::::.::::::.:::::. : ::::.::::
NP_001 GDSITEVFTNIYVTSFGPVSDTDMEYTIDVFFRQKWKDERLKFKGPMNILRLNNLMASKI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 WTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLYTMRLTISAECPMQLEDFPMDAHACP
:::::::::::::.::::: ::::::..::::::::::::..:::::.:::::::::.::
NP_001 WTPDTFFHNGKKSVAHNMTMPNKLLRIQDDGTLLYTMRLTVQAECPMHLEDFPMDAHSCP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 LKFGSYAYPNSEVVYVWTNGSTKSVVVAEDGSRLNQYHLMGQTVGTENISTSTGEYTIMT
:::::::: .:::.:.:: ... :: :: :::::::: :.::..: :.:..::::::.::
NP_001 LKFGSYAYTTSEVTYIWTYNASDSVQVAPDGSRLNQYDLLGQSIGKETIKSSTGEYTVMT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 AHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISAR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 NSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGWAWDGKKALEAAKIKKKREV
::::::::::::::::::::::::::::::::::::::::::::::.... : .: .
NP_001 NSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGWAWDGKSVVNDKKKEKASVM
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 ILNKSTNAFTTGKMSHPPNIPKEQ--TPAGTSNTTSVSVKPSEEKTSESKKTYNSISKID
: : ::.... .. ::. :. . . : :: : :.: .:.:::.::.::::
NP_001 IQN---NAYAVAVANYAPNLSKDPVLSTISKSATTPEPNKKPENKPAEAKKTFNSVSKID
370 380 390 400 410
430 440 450 460
pF1KE4 KMSRIVFPVLFGTFNLVYWATYLNREPVIKGAASPK
.:::::::::::::::::::::::::::. ..::
NP_001 RMSRIVFPVLFGTFNLVYWATYLNREPVL--GVSP
420 430 440 450
>>XP_016863471 (OMIM: 103780,137140) PREDICTED: gamma-am (451 aa)
initn: 2174 init1: 1875 opt: 2156 Z-score: 2542.7 bits: 479.7 E(85289): 6.8e-135
Smith-Waterman score: 2156; 76.5% identity (89.9% similar) in 425 aa overlap (39-461:32-451)
10 20 30 40 50 60
pF1KE4 FIMIKNLLLFCISMNLSSHFGFSQMPTSSVKDETNDNITIFTRILDGLLDGYDNRLRPGL
.::...:::::::::: :::::::::::::
XP_016 KTKLNIYNMQFLLFVFLVWDPARLVLANIQEDEAKNNITIFTRILDRLLDGYDNRLRPGL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 GERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQSWKDERLRFKGPMQRLPLNNLLASKI
:. ::.: :.::::::::::::.:::::::::::.::::::.:::::. : ::::.::::
XP_016 GDSITEVFTNIYVTSFGPVSDTDMEYTIDVFFRQKWKDERLKFKGPMNILRLNNLMASKI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 WTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLYTMRLTISAECPMQLEDFPMDAHACP
:::::::::::::.::::: ::::::..::::::::::::..:::::.:::::::::.::
XP_016 WTPDTFFHNGKKSVAHNMTMPNKLLRIQDDGTLLYTMRLTVQAECPMHLEDFPMDAHSCP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 LKFGSYAYPNSEVVYVWTNGSTKSVVVAEDGSRLNQYHLMGQTVGTENISTSTGEYTIMT
:::::::: .:::.:.:: ... :: :: :::::::: :.::..: :.:..::::::.::
XP_016 LKFGSYAYTTSEVTYIWTYNASDSVQVAPDGSRLNQYDLLGQSIGKETIKSSTGEYTVMT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 AHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISAR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 NSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGWAWDGKKALEAAKIKKKREV
::::::::::::::::::::::::::::::::::::::::::::::.... : .: .
XP_016 NSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGWAWDGKSVVNDKKKEKASVM
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 ILNKSTNAFTTGKMSHPPNIPKEQ--TPAGTSNTTSVSVKPSEEKTSESKKTYNSISKID
: : ::.... .. ::. :. . . : :: : :.: .:.:::.::.::::
XP_016 IQN---NAYAVAVANYAPNLSKDPVLSTISKSATTPEPNKKPENKPAEAKKTFNSVSKID
370 380 390 400 410
430 440 450 460
pF1KE4 KMSRIVFPVLFGTFNLVYWATYLNREPVIKGAASPK
.:::::::::::::::::::::::::::. ..::
XP_016 RMSRIVFPVLFGTFNLVYWATYLNREPVL--GVSP
420 430 440 450
>>XP_016863472 (OMIM: 103780,137140) PREDICTED: gamma-am (451 aa)
initn: 2174 init1: 1875 opt: 2156 Z-score: 2542.7 bits: 479.7 E(85289): 6.8e-135
Smith-Waterman score: 2156; 76.5% identity (89.9% similar) in 425 aa overlap (39-461:32-451)
10 20 30 40 50 60
pF1KE4 FIMIKNLLLFCISMNLSSHFGFSQMPTSSVKDETNDNITIFTRILDGLLDGYDNRLRPGL
.::...:::::::::: :::::::::::::
XP_016 KTKLNIYNMQFLLFVFLVWDPARLVLANIQEDEAKNNITIFTRILDRLLDGYDNRLRPGL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 GERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQSWKDERLRFKGPMQRLPLNNLLASKI
:. ::.: :.::::::::::::.:::::::::::.::::::.:::::. : ::::.::::
XP_016 GDSITEVFTNIYVTSFGPVSDTDMEYTIDVFFRQKWKDERLKFKGPMNILRLNNLMASKI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 WTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLYTMRLTISAECPMQLEDFPMDAHACP
:::::::::::::.::::: ::::::..::::::::::::..:::::.:::::::::.::
XP_016 WTPDTFFHNGKKSVAHNMTMPNKLLRIQDDGTLLYTMRLTVQAECPMHLEDFPMDAHSCP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 LKFGSYAYPNSEVVYVWTNGSTKSVVVAEDGSRLNQYHLMGQTVGTENISTSTGEYTIMT
:::::::: .:::.:.:: ... :: :: :::::::: :.::..: :.:..::::::.::
XP_016 LKFGSYAYTTSEVTYIWTYNASDSVQVAPDGSRLNQYDLLGQSIGKETIKSSTGEYTVMT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 AHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISAR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 NSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGWAWDGKKALEAAKIKKKREV
::::::::::::::::::::::::::::::::::::::::::::::.... : .: .
XP_016 NSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGWAWDGKSVVNDKKKEKASVM
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 ILNKSTNAFTTGKMSHPPNIPKEQ--TPAGTSNTTSVSVKPSEEKTSESKKTYNSISKID
: : ::.... .. ::. :. . . : :: : :.: .:.:::.::.::::
XP_016 IQN---NAYAVAVANYAPNLSKDPVLSTISKSATTPEPNKKPENKPAEAKKTFNSVSKID
370 380 390 400 410
430 440 450 460
pF1KE4 KMSRIVFPVLFGTFNLVYWATYLNREPVIKGAASPK
.:::::::::::::::::::::::::::. ..::
XP_016 RMSRIVFPVLFGTFNLVYWATYLNREPVL--GVSP
420 430 440 450
>>NP_000798 (OMIM: 103780,137140) gamma-aminobutyric aci (451 aa)
initn: 2174 init1: 1875 opt: 2156 Z-score: 2542.7 bits: 479.7 E(85289): 6.8e-135
Smith-Waterman score: 2156; 76.5% identity (89.9% similar) in 425 aa overlap (39-461:32-451)
10 20 30 40 50 60
pF1KE4 FIMIKNLLLFCISMNLSSHFGFSQMPTSSVKDETNDNITIFTRILDGLLDGYDNRLRPGL
.::...:::::::::: :::::::::::::
NP_000 KTKLNIYNMQFLLFVFLVWDPARLVLANIQEDEAKNNITIFTRILDRLLDGYDNRLRPGL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 GERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQSWKDERLRFKGPMQRLPLNNLLASKI
:. ::.: :.::::::::::::.:::::::::::.::::::.:::::. : ::::.::::
NP_000 GDSITEVFTNIYVTSFGPVSDTDMEYTIDVFFRQKWKDERLKFKGPMNILRLNNLMASKI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 WTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLYTMRLTISAECPMQLEDFPMDAHACP
:::::::::::::.::::: ::::::..::::::::::::..:::::.:::::::::.::
NP_000 WTPDTFFHNGKKSVAHNMTMPNKLLRIQDDGTLLYTMRLTVQAECPMHLEDFPMDAHSCP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 LKFGSYAYPNSEVVYVWTNGSTKSVVVAEDGSRLNQYHLMGQTVGTENISTSTGEYTIMT
:::::::: .:::.:.:: ... :: :: :::::::: :.::..: :.:..::::::.::
NP_000 LKFGSYAYTTSEVTYIWTYNASDSVQVAPDGSRLNQYDLLGQSIGKETIKSSTGEYTVMT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 AHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 AHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISAR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 NSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGWAWDGKKALEAAKIKKKREV
::::::::::::::::::::::::::::::::::::::::::::::.... : .: .
NP_000 NSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGWAWDGKSVVNDKKKEKASVM
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 ILNKSTNAFTTGKMSHPPNIPKEQ--TPAGTSNTTSVSVKPSEEKTSESKKTYNSISKID
: : ::.... .. ::. :. . . : :: : :.: .:.:::.::.::::
NP_000 IQN---NAYAVAVANYAPNLSKDPVLSTISKSATTPEPNKKPENKPAEAKKTFNSVSKID
370 380 390 400 410
430 440 450 460
pF1KE4 KMSRIVFPVLFGTFNLVYWATYLNREPVIKGAASPK
.:::::::::::::::::::::::::::. ..::
NP_000 RMSRIVFPVLFGTFNLVYWATYLNREPVL--GVSP
420 430 440 450
>>NP_001121116 (OMIM: 137160,611136,615744) gamma-aminob (456 aa)
initn: 2077 init1: 1831 opt: 2113 Z-score: 2492.0 bits: 470.4 E(85289): 4.6e-132
Smith-Waterman score: 2113; 73.5% identity (86.0% similar) in 442 aa overlap (24-461:18-454)
10 20 30 40 50 60
pF1KE4 MDNGMFSGFIMIKNLLLFCISMNLSSHFGFSQMPTSSVKDETNDNITIFTRILDGLLDGY
::. : : . :..:: .:: :.:::::: :::::
NP_001 MRKSPGLSDCLWAWILLLSTLTGRS-YGQPSLQDELKDNTTVFTRILDRLLDGY
10 20 30 40 50
70 80 90 100 110 120
pF1KE4 DNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQSWKDERLRFKGPMQRLPL
:::::::::::.:.:.:::.::::::::: .::::::::::::::::::.::::: : :
NP_001 DNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERLKFKGPMTVLRL
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE4 NNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLYTMRLTISAECPMQLEDF
:::.:::::::::::::::::.::::: ::::::. .:::::::::::. :::::.::::
NP_001 NNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTVRAECPMHLEDF
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE4 PMDAHACPLKFGSYAYPNSEVVYVWTNGSTKSVVVAEDGSRLNQYHLMGQTVGTENISTS
:::::::::::::::: .:::: :: ..:::::::::::::: :.:::: . ...:
NP_001 PMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLLGQTVDSGIVQSS
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE4 TGEYTIMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTM
::::..::.:::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTM
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE4 TTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGWAWDGKKALEAA
::::::::::::::::::::::::::::::::::::::::::::::::.:::::...
NP_001 TTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGYAWDGKSVVPE-
300 310 320 330 340 350
370 380 390 400 410
pF1KE4 KIKKKREVILNKSTNAFTTGKMSHPPNI----PKEQTPAGTSNTTSVSVKPSEEKTSESK
: :: .. ...:. :... :. ::. : : : ... ::: : : : :
NP_001 KPKKVKDPLIKKN-NTYAPTATSYTPNLARGDPGLATIAKSATIEPKEVKP-ETKPPEPK
360 370 380 390 400 410
420 430 440 450 460
pF1KE4 KTYNSISKIDKMSRIVFPVLFGTFNLVYWATYLNREPVIKGAASPK
::.::.::::..:::.::.::: :::::::::::::: .: : .:
NP_001 KTFNSVSKIDRLSRIAFPLLFGIFNLVYWATYLNREPQLK-APTPHQ
420 430 440 450
>>NP_000797 (OMIM: 137160,611136,615744) gamma-aminobuty (456 aa)
initn: 2077 init1: 1831 opt: 2113 Z-score: 2492.0 bits: 470.4 E(85289): 4.6e-132
Smith-Waterman score: 2113; 73.5% identity (86.0% similar) in 442 aa overlap (24-461:18-454)
10 20 30 40 50 60
pF1KE4 MDNGMFSGFIMIKNLLLFCISMNLSSHFGFSQMPTSSVKDETNDNITIFTRILDGLLDGY
::. : : . :..:: .:: :.:::::: :::::
NP_000 MRKSPGLSDCLWAWILLLSTLTGRS-YGQPSLQDELKDNTTVFTRILDRLLDGY
10 20 30 40 50
70 80 90 100 110 120
pF1KE4 DNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQSWKDERLRFKGPMQRLPL
:::::::::::.:.:.:::.::::::::: .::::::::::::::::::.::::: : :
NP_000 DNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERLKFKGPMTVLRL
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE4 NNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLYTMRLTISAECPMQLEDF
:::.:::::::::::::::::.::::: ::::::. .:::::::::::. :::::.::::
NP_000 NNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTVRAECPMHLEDF
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE4 PMDAHACPLKFGSYAYPNSEVVYVWTNGSTKSVVVAEDGSRLNQYHLMGQTVGTENISTS
:::::::::::::::: .:::: :: ..:::::::::::::: :.:::: . ...:
NP_000 PMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLLGQTVDSGIVQSS
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE4 TGEYTIMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTM
::::..::.:::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 TGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTM
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE4 TTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGWAWDGKKALEAA
::::::::::::::::::::::::::::::::::::::::::::::::.:::::...
NP_000 TTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGYAWDGKSVVPE-
300 310 320 330 340 350
370 380 390 400 410
pF1KE4 KIKKKREVILNKSTNAFTTGKMSHPPNI----PKEQTPAGTSNTTSVSVKPSEEKTSESK
: :: .. ...:. :... :. ::. : : : ... ::: : : : :
NP_000 KPKKVKDPLIKKN-NTYAPTATSYTPNLARGDPGLATIAKSATIEPKEVKP-ETKPPEPK
360 370 380 390 400 410
420 430 440 450 460
pF1KE4 KTYNSISKIDKMSRIVFPVLFGTFNLVYWATYLNREPVIKGAASPK
::.::.::::..:::.::.::: :::::::::::::: .: : .:
NP_000 KTFNSVSKIDRLSRIAFPLLFGIFNLVYWATYLNREPQLK-APTPHQ
420 430 440 450
462 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 01:04:27 2016 done: Sun Nov 6 01:04:28 2016
Total Scan time: 5.890 Total Display time: 0.070
Function used was FASTA [36.3.4 Apr, 2011]