Result of FASTA (ccds) for
pFN21AE4437
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE4437, 453 aa
1>>>pF1KE4437 453 - 453 aa - 453 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.3172+/-0.000899; mu= 17.4975+/- 0.054
mean_var=68.0395+/-13.314, 0's: 0 Z-trim(106.1): 43 B-trim: 124 in 1/50
Lambda= 0.155487
statistics sampled from 8774 (8815) to 8774 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.642), E-opt: 0.2 (0.271), width: 16
Scan time: 2.570
The best scores are: opt bits E(32554)
CCDS11212.1 ALDH3A1 gene_id:218|Hs108|chr17 ( 453) 2987 679.2 2.3e-195
CCDS82090.1 ALDH3A1 gene_id:218|Hs108|chr17 ( 380) 2529 576.4 1.7e-164
CCDS11210.1 ALDH3A2 gene_id:224|Hs108|chr17 ( 485) 2113 483.2 2.6e-136
CCDS32589.1 ALDH3A2 gene_id:224|Hs108|chr17 ( 508) 2113 483.2 2.7e-136
CCDS73335.1 ALDH3B1 gene_id:221|Hs108|chr11 ( 468) 1670 383.8 2.1e-106
CCDS73336.1 ALDH3B1 gene_id:221|Hs108|chr11 ( 431) 1453 335.1 8.7e-92
CCDS31622.1 ALDH3B2 gene_id:222|Hs108|chr11 ( 385) 1346 311.0 1.3e-84
CCDS76443.1 ALDH3B1 gene_id:221|Hs108|chr11 ( 351) 683 162.3 7.2e-40
CCDS10389.1 ALDH1A3 gene_id:220|Hs108|chr15 ( 512) 586 140.6 3.5e-33
CCDS6644.1 ALDH1A1 gene_id:216|Hs108|chr9 ( 501) 571 137.3 3.5e-32
CCDS9155.1 ALDH2 gene_id:217|Hs108|chr12 ( 517) 557 134.1 3.2e-31
CCDS6615.1 ALDH1B1 gene_id:219|Hs108|chr9 ( 517) 552 133.0 7e-31
CCDS55968.1 ALDH1A2 gene_id:8854|Hs108|chr15 ( 497) 547 131.9 1.5e-30
CCDS10163.1 ALDH1A2 gene_id:8854|Hs108|chr15 ( 518) 547 131.9 1.5e-30
CCDS45266.1 ALDH1A2 gene_id:8854|Hs108|chr15 ( 422) 516 124.9 1.6e-28
CCDS55885.1 ALDH2 gene_id:217|Hs108|chr12 ( 470) 512 124.0 3.2e-28
CCDS31891.1 ALDH1L2 gene_id:160428|Hs108|chr12 ( 923) 503 122.2 2.3e-27
CCDS4555.1 ALDH5A1 gene_id:7915|Hs108|chr6 ( 535) 484 117.8 2.8e-26
CCDS58850.1 ALDH1L1 gene_id:10840|Hs108|chr3 ( 801) 447 109.6 1.2e-23
CCDS3034.1 ALDH1L1 gene_id:10840|Hs108|chr3 ( 902) 447 109.6 1.4e-23
CCDS58851.1 ALDH1L1 gene_id:10840|Hs108|chr3 ( 912) 447 109.6 1.4e-23
CCDS1250.2 ALDH9A1 gene_id:223|Hs108|chr1 ( 518) 441 108.1 2.2e-23
CCDS76794.1 ALDH1A3 gene_id:220|Hs108|chr15 ( 405) 432 106.0 7.2e-23
CCDS10164.1 ALDH1A2 gene_id:8854|Hs108|chr15 ( 480) 376 93.5 5e-19
CCDS4137.2 ALDH7A1 gene_id:501|Hs108|chr5 ( 539) 371 92.4 1.2e-18
CCDS4556.1 ALDH5A1 gene_id:7915|Hs108|chr6 ( 548) 350 87.7 3.2e-17
>>CCDS11212.1 ALDH3A1 gene_id:218|Hs108|chr17 (453 aa)
initn: 2987 init1: 2987 opt: 2987 Z-score: 3620.8 bits: 679.2 E(32554): 2.3e-195
Smith-Waterman score: 2987; 99.8% identity (100.0% similar) in 453 aa overlap (1-453:1-453)
10 20 30 40 50 60
pF1KE4 MSKISEAVKRARAAFSSGRTRPLQFRIQQLEALQRLIQEQEQELVGALAADLHKNEWNAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 MSKISEAVKRARAAFSSGRTRPLQFRIQQLEALQRLIQEQEQELVGALAADLHKNEWNAY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 YEEVVYVLEEIEYMIQKLPEWAADEPVEKTPQTQQDELYIHSEPLGVVLVIGTWNYPFNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 YEEVVYVLEEIEYMIQKLPEWAADEPVEKTPQTQQDELYIHSEPLGVVLVIGTWNYPFNL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 TIQPMVGAIAAGNAVVLKPSELSENMASLLATIIPQYLDKDLYPVINGGVPETTELLKER
:::::::::::::.::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 TIQPMVGAIAAGNSVVLKPSELSENMASLLATIIPQYLDKDLYPVINGGVPETTELLKER
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 FDHILYTGSTGVGKIIMTAAAKHLTPVTLELGGKSPCYVDKNCDLDVACRRIAWGKFMNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 FDHILYTGSTGVGKIIMTAAAKHLTPVTLELGGKSPCYVDKNCDLDVACRRIAWGKFMNS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 GQTCVAPDYILCDPSIQNQIVEKLKKSLKEFYGEDAKKSRDYGRIISARHFQRVMGLIEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 GQTCVAPDYILCDPSIQNQIVEKLKKSLKEFYGEDAKKSRDYGRIISARHFQRVMGLIEG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 QKVAYGGTGDAATRYIAPTILTDVDPQSPVMQEEIFGPVLPIVCVRSLEEAIQFINQREK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 QKVAYGGTGDAATRYIAPTILTDVDPQSPVMQEEIFGPVLPIVCVRSLEEAIQFINQREK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 PLALYMFSSNDKVIKKMIAETSSGGVAANDVIVHITLHSLPFGGVGNSGMGSYHGKKSFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 PLALYMFSSNDKVIKKMIAETSSGGVAANDVIVHITLHSLPFGGVGNSGMGSYHGKKSFE
370 380 390 400 410 420
430 440 450
pF1KE4 TFSHRRSCLVRPLMNDEGLKVRYPPSPAKMTQH
:::::::::::::::::::::::::::::::::
CCDS11 TFSHRRSCLVRPLMNDEGLKVRYPPSPAKMTQH
430 440 450
>>CCDS82090.1 ALDH3A1 gene_id:218|Hs108|chr17 (380 aa)
initn: 2529 init1: 2529 opt: 2529 Z-score: 3066.7 bits: 576.4 E(32554): 1.7e-164
Smith-Waterman score: 2529; 99.7% identity (100.0% similar) in 380 aa overlap (74-453:1-380)
50 60 70 80 90 100
pF1KE4 LVGALAADLHKNEWNAYYEEVVYVLEEIEYMIQKLPEWAADEPVEKTPQTQQDELYIHSE
::::::::::::::::::::::::::::::
CCDS82 MIQKLPEWAADEPVEKTPQTQQDELYIHSE
10 20 30
110 120 130 140 150 160
pF1KE4 PLGVVLVIGTWNYPFNLTIQPMVGAIAAGNAVVLKPSELSENMASLLATIIPQYLDKDLY
::::::::::::::::::::::::::::::.:::::::::::::::::::::::::::::
CCDS82 PLGVVLVIGTWNYPFNLTIQPMVGAIAAGNSVVLKPSELSENMASLLATIIPQYLDKDLY
40 50 60 70 80 90
170 180 190 200 210 220
pF1KE4 PVINGGVPETTELLKERFDHILYTGSTGVGKIIMTAAAKHLTPVTLELGGKSPCYVDKNC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 PVINGGVPETTELLKERFDHILYTGSTGVGKIIMTAAAKHLTPVTLELGGKSPCYVDKNC
100 110 120 130 140 150
230 240 250 260 270 280
pF1KE4 DLDVACRRIAWGKFMNSGQTCVAPDYILCDPSIQNQIVEKLKKSLKEFYGEDAKKSRDYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 DLDVACRRIAWGKFMNSGQTCVAPDYILCDPSIQNQIVEKLKKSLKEFYGEDAKKSRDYG
160 170 180 190 200 210
290 300 310 320 330 340
pF1KE4 RIISARHFQRVMGLIEGQKVAYGGTGDAATRYIAPTILTDVDPQSPVMQEEIFGPVLPIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 RIISARHFQRVMGLIEGQKVAYGGTGDAATRYIAPTILTDVDPQSPVMQEEIFGPVLPIV
220 230 240 250 260 270
350 360 370 380 390 400
pF1KE4 CVRSLEEAIQFINQREKPLALYMFSSNDKVIKKMIAETSSGGVAANDVIVHITLHSLPFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 CVRSLEEAIQFINQREKPLALYMFSSNDKVIKKMIAETSSGGVAANDVIVHITLHSLPFG
280 290 300 310 320 330
410 420 430 440 450
pF1KE4 GVGNSGMGSYHGKKSFETFSHRRSCLVRPLMNDEGLKVRYPPSPAKMTQH
::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 GVGNSGMGSYHGKKSFETFSHRRSCLVRPLMNDEGLKVRYPPSPAKMTQH
340 350 360 370 380
>>CCDS11210.1 ALDH3A2 gene_id:224|Hs108|chr17 (485 aa)
initn: 2092 init1: 2092 opt: 2113 Z-score: 2560.8 bits: 483.2 E(32554): 2.6e-136
Smith-Waterman score: 2113; 67.9% identity (90.9% similar) in 439 aa overlap (8-446:5-443)
10 20 30 40 50 60
pF1KE4 MSKISEAVKRARAAFSSGRTRPLQFRIQQLEALQRLIQEQEQELVGALAADLHKNEWNAY
:.:.: :: :::.:::.::.::::::.:..::.:.... :.:::: :.:.:.:
CCDS11 MELEVRRVRQAFLSGRSRPLRFRLQQLEALRRMVQEREKDILTAIAADLCKSEFNVY
10 20 30 40 50
70 80 90 100 110 120
pF1KE4 YEEVVYVLEEIEYMIQKLPEWAADEPVEKTPQTQQDELYIHSEPLGVVLVIGTWNYPFNL
.::. :: ::..:...::::.. .::.:. :. :: ::. .::::::.::.::::: :
CCDS11 SQEVITVLGEIDFMLENLPEWVTAKPVKKNVLTMLDEAYIQPQPLGVVLIIGAWNYPFVL
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE4 TIQPMVGAIAAGNAVVLKPSELSENMASLLATIIPQYLDKDLYPVINGGVPETTELLKER
::::..:::::::::..:::::::: :..:: ..:::::.::: :::::: :::::::.:
CCDS11 TIQPLIGAIAAGNAVIIKPSELSENTAKILAKLLPQYLDQDLYIVINGGVEETTELLKQR
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE4 FDHILYTGSTGVGKIIMTAAAKHLTPVTLELGGKSPCYVDKNCDLDVACRRIAWGKFMNS
::::.:::.:.::::.: ::::::::::::::::::::.::.::::..::::.:::.::
CCDS11 FDHIFYTGNTAVGKIVMEAAAKHLTPVTLELGGKSPCYIDKDCDLDIVCRRITWGKYMNC
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE4 GQTCVAPDYILCDPSIQNQIVEKLKKSLKEFYGEDAKKSRDYGRIISARHFQRVMGLIEG
::::.:::::::. :.::::: :.:...::::::. :.: :: :::. :::.:...:.::
CCDS11 GQTCIAPDYILCEASLQNQIVWKIKETVKEFYGENIKESPDYERIINLRHFKRILSLLEG
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE4 QKVAYGGTGDAATRYIAPTILTDVDPQSPVMQEEIFGPVLPIVCVRSLEEAIQFINQREK
::.:.:: : ::::::::.::::::.. :::::::::.:::: :....:::.:::.:::
CCDS11 QKIAFGGETDEATRYIAPTVLTDVDPKTKVMQEEIFGPILPIVPVKNVDEAINFINEREK
300 310 320 330 340 350
370 380 390 400 410 420
pF1KE4 PLALYMFSSNDKVIKKMIAETSSGGVAANDVIVHITLHSLPFGGVGNSGMGSYHGKKSFE
:::::.:: : :.::.:: :::::::..::::.:.::.:.::::::.::::.::::.::.
CCDS11 PLALYVFSHNHKLIKRMIDETSSGGVTGNDVIMHFTLNSFPFGGVGSSGMGAYHGKHSFD
360 370 380 390 400 410
430 440 450
pF1KE4 TFSHRRSCLVRPLMNDEGLKVRYPPSPAKMTQH
::::.: ::.. : . . :.::::.
CCDS11 TFSHQRPCLLKSLKREGANKLRYPPNSQSKVDWGKFFLLKRFNKEKLGLLLLTFLGIVAA
420 430 440 450 460 470
>>CCDS32589.1 ALDH3A2 gene_id:224|Hs108|chr17 (508 aa)
initn: 2092 init1: 2092 opt: 2113 Z-score: 2560.5 bits: 483.2 E(32554): 2.7e-136
Smith-Waterman score: 2113; 67.9% identity (90.9% similar) in 439 aa overlap (8-446:5-443)
10 20 30 40 50 60
pF1KE4 MSKISEAVKRARAAFSSGRTRPLQFRIQQLEALQRLIQEQEQELVGALAADLHKNEWNAY
:.:.: :: :::.:::.::.::::::.:..::.:.... :.:::: :.:.:.:
CCDS32 MELEVRRVRQAFLSGRSRPLRFRLQQLEALRRMVQEREKDILTAIAADLCKSEFNVY
10 20 30 40 50
70 80 90 100 110 120
pF1KE4 YEEVVYVLEEIEYMIQKLPEWAADEPVEKTPQTQQDELYIHSEPLGVVLVIGTWNYPFNL
.::. :: ::..:...::::.. .::.:. :. :: ::. .::::::.::.::::: :
CCDS32 SQEVITVLGEIDFMLENLPEWVTAKPVKKNVLTMLDEAYIQPQPLGVVLIIGAWNYPFVL
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE4 TIQPMVGAIAAGNAVVLKPSELSENMASLLATIIPQYLDKDLYPVINGGVPETTELLKER
::::..:::::::::..:::::::: :..:: ..:::::.::: :::::: :::::::.:
CCDS32 TIQPLIGAIAAGNAVIIKPSELSENTAKILAKLLPQYLDQDLYIVINGGVEETTELLKQR
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE4 FDHILYTGSTGVGKIIMTAAAKHLTPVTLELGGKSPCYVDKNCDLDVACRRIAWGKFMNS
::::.:::.:.::::.: ::::::::::::::::::::.::.::::..::::.:::.::
CCDS32 FDHIFYTGNTAVGKIVMEAAAKHLTPVTLELGGKSPCYIDKDCDLDIVCRRITWGKYMNC
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE4 GQTCVAPDYILCDPSIQNQIVEKLKKSLKEFYGEDAKKSRDYGRIISARHFQRVMGLIEG
::::.:::::::. :.::::: :.:...::::::. :.: :: :::. :::.:...:.::
CCDS32 GQTCIAPDYILCEASLQNQIVWKIKETVKEFYGENIKESPDYERIINLRHFKRILSLLEG
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE4 QKVAYGGTGDAATRYIAPTILTDVDPQSPVMQEEIFGPVLPIVCVRSLEEAIQFINQREK
::.:.:: : ::::::::.::::::.. :::::::::.:::: :....:::.:::.:::
CCDS32 QKIAFGGETDEATRYIAPTVLTDVDPKTKVMQEEIFGPILPIVPVKNVDEAINFINEREK
300 310 320 330 340 350
370 380 390 400 410 420
pF1KE4 PLALYMFSSNDKVIKKMIAETSSGGVAANDVIVHITLHSLPFGGVGNSGMGSYHGKKSFE
:::::.:: : :.::.:: :::::::..::::.:.::.:.::::::.::::.::::.::.
CCDS32 PLALYVFSHNHKLIKRMIDETSSGGVTGNDVIMHFTLNSFPFGGVGSSGMGAYHGKHSFD
360 370 380 390 400 410
430 440 450
pF1KE4 TFSHRRSCLVRPLMNDEGLKVRYPPSPAKMTQH
::::.: ::.. : . . :.::::.
CCDS32 TFSHQRPCLLKSLKREGANKLRYPPNSQSKVDWGKFFLLKRFNKEKLGLLLLTFLGIVAA
420 430 440 450 460 470
>>CCDS73335.1 ALDH3B1 gene_id:221|Hs108|chr11 (468 aa)
initn: 1689 init1: 1639 opt: 1670 Z-score: 2023.9 bits: 383.8 E(32554): 2.1e-106
Smith-Waterman score: 1670; 53.7% identity (80.5% similar) in 451 aa overlap (1-450:1-451)
10 20 30 40 50 60
pF1KE4 MSKISEAVKRARAAFSSGRTRPLQFRIQQLEALQRLIQEQEQELVGALAADLHKNEWNAY
:. ......: : :: .::::: .:: ::..: :..::..: : ::: ::::. ...
CCDS73 MDPLGDTLRRLREAFHAGRTRPAEFRAAQLQGLGRFLQENKQLLHDALAQDLHKSAFESE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 YEEVVYVLEEIEYMIQKLPEWAADEPVEKTPQTQQDELYIHSEPLGVVLVIGTWNYPFNL
::. :. ...: : :: : :. :: : .:..::.:.::.:. ::::.::
CCDS73 VSEVAISQGEVTLALRNLRAWMKDERVPKNLATQLDSAFIRKEPFGLVLIIAPWNYPLNL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 TIQPMVGAIAAGNAVVLKPSELSENMASLLATIIPQYLDKDLYPVINGGVPETTELLKER
:. :.:::.:::: :::::::.:.:. ..:: ..:::.:.. . :. :: :: .::..:
CCDS73 TLVPLVGALAAGNCVVLKPSEISKNVEKILAEVLPQYVDQSCFAVVLGGPQETGQLLEHR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 FDHILYTGSTGVGKIIMTAAAKHLTPVTLELGGKSPCYVDKNCDLDVACRRIAWGKFMNS
::.:..::: ::::.::::::::::::::::::.::::: ::: ... :.:: ...:.
CCDS73 FDYIFFTGSPRVGKIVMTAAAKHLTPVTLELGGKNPCYVDDNCDPQTVANRVAWFRYFNA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 GQTCVAPDYILCDPSIQNQIVEKLKKSLKEFYGEDAKKSRDYGRIISARHFQRVMGLIEG
:::::::::.::.: .:.... :.... .:::.: ..: . ::::. ..:::. .:.
CCDS73 GQTCVAPDYVLCSPEMQERLLPALQSTITRFYGDDPQSSPNLGRIINQKQFQRLRALLGC
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 QKVAYGGTGDAATRYIAPTILTDVDPQSPVMQEEIFGPVLPIVCVRSLEEAIQFINQREK
.:: :: .: . ::::::.:.::. . ::::::::::.:::: :.::.:::.:::.:::
CCDS73 GRVAIGGQSDESDRYIAPTVLVDVQEMEPVMQEEIFGPILPIVNVQSLDEAIEFINRREK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 PLALYMFSSNDKVIKKMIAETSSGGVAANDVIVHITLHSLPFGGVGNSGMGSYHGKKSFE
::::: ::....:.:.....::::: .:: ..:.:: :::::::: :::: :::: ::.
CCDS73 PLALYAFSNSSQVVKRVLTQTSSGGFCGNDGFMHMTLASLPFGGVGASGMGRYHGKFSFD
370 380 390 400 410 420
430 440 450
pF1KE4 TFSHRRSCLVRPLMNDEGLKVRYPP-SPAKMTQH
::::.:.::.: .. .:::: :: ..
CCDS73 TFSHHRACLLRSPGMEKLNALRYPPQSPRRLRMLLVAMEAQGCSCTLL
430 440 450 460
>>CCDS73336.1 ALDH3B1 gene_id:221|Hs108|chr11 (431 aa)
initn: 1634 init1: 1447 opt: 1453 Z-score: 1761.4 bits: 335.1 E(32554): 8.7e-92
Smith-Waterman score: 1544; 51.7% identity (76.3% similar) in 451 aa overlap (1-450:1-414)
10 20 30 40 50 60
pF1KE4 MSKISEAVKRARAAFSSGRTRPLQFRIQQLEALQRLIQEQEQELVGALAADLHKNEWNAY
:. ......: : :: .::::: .:: ::..: :..::..: : ::: ::::
CCDS73 MDPLGDTLRRLREAFHAGRTRPAEFRAAQLQGLGRFLQENKQLLHDALAQDLHKA-----
10 20 30 40 50
70 80 90 100 110 120
pF1KE4 YEEVVYVLEEIEYMIQKLPEWAADEPVEKTPQTQQDELYIHSEPLGVVLVIGTWNYPFNL
:: : .:..::.:.::.:. ::::.::
CCDS73 --------------------------------TQLDSAFIRKEPFGLVLIIAPWNYPLNL
60 70 80
130 140 150 160 170 180
pF1KE4 TIQPMVGAIAAGNAVVLKPSELSENMASLLATIIPQYLDKDLYPVINGGVPETTELLKER
:. :.:::.:::: :::::::.:.:. ..:: ..:::.:.. . :. :: :: .::..:
CCDS73 TLVPLVGALAAGNCVVLKPSEISKNVEKILAEVLPQYVDQSCFAVVLGGPQETGQLLEHR
90 100 110 120 130 140
190 200 210 220 230 240
pF1KE4 FDHILYTGSTGVGKIIMTAAAKHLTPVTLELGGKSPCYVDKNCDLDVACRRIAWGKFMNS
::.:..::: ::::.::::::::::::::::::.::::: ::: ... :.:: ...:.
CCDS73 FDYIFFTGSPRVGKIVMTAAAKHLTPVTLELGGKNPCYVDDNCDPQTVANRVAWFRYFNA
150 160 170 180 190 200
250 260 270 280 290 300
pF1KE4 GQTCVAPDYILCDPSIQNQIVEKLKKSLKEFYGEDAKKSRDYGRIISARHFQRVMGLIEG
:::::::::.::.: .:.... :.... .:::.: ..: . ::::. ..:::. .:.
CCDS73 GQTCVAPDYVLCSPEMQERLLPALQSTITRFYGDDPQSSPNLGRIINQKQFQRLRALLGC
210 220 230 240 250 260
310 320 330 340 350 360
pF1KE4 QKVAYGGTGDAATRYIAPTILTDVDPQSPVMQEEIFGPVLPIVCVRSLEEAIQFINQREK
.:: :: .: . ::::::.:.::. . ::::::::::.:::: :.::.:::.:::.:::
CCDS73 GRVAIGGQSDESDRYIAPTVLVDVQEMEPVMQEEIFGPILPIVNVQSLDEAIEFINRREK
270 280 290 300 310 320
370 380 390 400 410 420
pF1KE4 PLALYMFSSNDKVIKKMIAETSSGGVAANDVIVHITLHSLPFGGVGNSGMGSYHGKKSFE
::::: ::....:.:.....::::: .:: ..:.:: :::::::: :::: :::: ::.
CCDS73 PLALYAFSNSSQVVKRVLTQTSSGGFCGNDGFMHMTLASLPFGGVGASGMGRYHGKFSFD
330 340 350 360 370 380
430 440 450
pF1KE4 TFSHRRSCLVRPLMNDEGLKVRYPP-SPAKMTQH
::::.:.::.: .. .:::: :: ..
CCDS73 TFSHHRACLLRSPGMEKLNALRYPPQSPRRLRMLLVAMEAQGCSCTLL
390 400 410 420 430
>>CCDS31622.1 ALDH3B2 gene_id:222|Hs108|chr11 (385 aa)
initn: 1346 init1: 1346 opt: 1346 Z-score: 1632.4 bits: 311.0 E(32554): 1.3e-84
Smith-Waterman score: 1346; 52.5% identity (82.9% similar) in 362 aa overlap (84-445:3-364)
60 70 80 90 100 110
pF1KE4 KNEWNAYYEEVVYVLEEIEYMIQKLPEWAADEPVEKTPQTQQDELYIHSEPLGVVLVIGT
::: . . : ..: .::.:.::.:.
CCDS31 MKDEPRSTNLFMKLDSVFIWKEPFGLVLIIAP
10 20 30
120 130 140 150 160 170
pF1KE4 WNYPFNLTIQPMVGAIAAGNAVVLKPSELSENMASLLATIIPQYLDKDLYPVINGGVPET
::::.:::. .:::.:::. :::::::.:.. ..:: ..:::::.. . :. :: ::
CCDS31 WNYPLNLTLVLLVGALAAGSCVVLKPSEISQGTEKVLAEVLPQYLDQSCFAVVLGGPQET
40 50 60 70 80 90
180 190 200 210 220 230
pF1KE4 TELLKERFDHILYTGSTGVGKIIMTAAAKHLTPVTLELGGKSPCYVDKNCDLDVACRRIA
.::....:.:..::: ::::.::::.:::::::::::::.::::: ::: ... :.:
CCDS31 GQLLEHKLDYIFFTGSPRVGKIVMTAATKHLTPVTLELGGKNPCYVDDNCDPQTVANRVA
100 110 120 130 140 150
240 250 260 270 280 290
pF1KE4 WGKFMNSGQTCVAPDYILCDPSIQNQIVEKLKKSLKEFYGEDAKKSRDYGRIISARHFQR
: ..:.:::::::::.::.: .:.... :.... .:::.: ..: . :.::. ..:::
CCDS31 WFCYFNAGQTCVAPDYVLCSPEMQERLLPALQSTITRFYGDDPQSSPNLGHIINQKQFQR
160 170 180 190 200 210
300 310 320 330 340 350
pF1KE4 VMGLIEGQKVAYGGTGDAATRYIAPTILTDVDPQSPVMQEEIFGPVLPIVCVRSLEEAIQ
. .:. ..:: :: .. . ::::::.:.::. ::::::::::.:::: :.:..:::.
CCDS31 LRALLGCSRVAIGGQSNESDRYIAPTVLVDVQETEPVMQEEIFGPILPIVNVQSVDEAIK
220 230 240 250 260 270
360 370 380 390 400 410
pF1KE4 FINQREKPLALYMFSSNDKVIKKMIAETSSGGVAANDVIVHITLHSLPFGGVGNSGMGSY
:::..::::::: ::....:...:. .::::. ..:. ...:.: :.::::::.:::: :
CCDS31 FINRQEKPLALYAFSNSSQVVNQMLERTSSGSFGGNEGFTYISLLSVPFGGVGHSGMGRY
280 290 300 310 320 330
420 430 440 450
pF1KE4 HGKKSFETFSHRRSCLVRPLMNDEGLKVRYPPSPAKMTQH
::: .:.::::.:.::. : .. ...:::
CCDS31 HGKFTFDTFSHHRTCLLAPSGLEKLKEIHYPPYTDWNQQLLRWGMGSQSCTLL
340 350 360 370 380
>>CCDS76443.1 ALDH3B1 gene_id:221|Hs108|chr11 (351 aa)
initn: 1179 init1: 660 opt: 683 Z-score: 829.2 bits: 162.3 E(32554): 7.2e-40
Smith-Waterman score: 937; 40.0% identity (59.2% similar) in 453 aa overlap (1-450:1-334)
10 20 30 40 50 60
pF1KE4 MSKISEAVKRARAAFSSGRTRPLQFRIQQLEALQRLIQEQEQELVGALAADLHKNEWNAY
:. ......: : :: .::::: .:: ::..: :..::..: : ::: ::::. ...
CCDS76 MDPLGDTLRRLREAFHAGRTRPAEFRAAQLQGLGRFLQENKQLLHDALAQDLHKSAFESE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 YEEVVYVLEEIEYMIQKLPEWAADEPVEKTPQTQQDELYIHSEPLGVVLVIGTWNYPFNL
::. :. ...: : :: : :. :: : .:..::.:.::.:. ::::.::
CCDS76 VSEVAISQGEVTLALRNLRAWMKDERVPKNLATQLDSAFIRKEPFGLVLIIAPWNYPLNL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 TIQPMVGAIAAGNAVVLKPSELSENMASLLATIIPQYLDKDLYPVINGGVPETTELLKER
:. :.:::.:::: :::::::.:.:. ..:: ..:::.:..
CCDS76 TLVPLVGALAAGNCVVLKPSEISKNVEKILAEVLPQYVDQS-------------------
130 140 150 160
190 200 210 220 230 240
pF1KE4 FDHILYTGSTGVGKIIMTAAAKHLTPVTLELGGKSPCYVDKNCDLDVACRRIAWGKFMNS
::
CCDS76 ----------------------------------SP------------------------
250 260 270 280 290 300
pF1KE4 GQTCVAPDYILCDPSIQNQIVEKLKKSLKEFYGEDAKKSRDYGRIISARHFQRVMGLIEG
. ::::. ..:::. .:.
CCDS76 ----------------------------------------NLGRIINQKQFQRLRALLGC
170 180
310 320 330 340 350 360
pF1KE4 QKVAYGGTGDAATRYIAPTILTDVDPQSPVMQEEIFGPVLPIVCVRSLEEAIQFINQREK
.:: :: .: . ::::::.:.::. . ::::::::::.:::: :.::.:::.:::.:::
CCDS76 GRVAIGGQSDESDRYIAPTVLVDVQEMEPVMQEEIFGPILPIVNVQSLDEAIEFINRREK
190 200 210 220 230 240
370 380 390 400 410 420
pF1KE4 PLALYMFSSNDKVIKKMIAETSSGGVAANDVIVHITLHSLPFGGVGNSGMGSYHGKKSFE
::::: ::....:.:.....::::: .:: ..:.:: :::::::: :::: :::: ::.
CCDS76 PLALYAFSNSSQVVKRVLTQTSSGGFCGNDGFMHMTLASLPFGGVGASGMGRYHGKFSFD
250 260 270 280 290 300
430 440 450
pF1KE4 TFSHRRSCLVR-PLMNDEGLK-VRYPP-SPAKMTQH
::::.:.::.: : : : :. .:::: :: ..
CCDS76 TFSHHRACLLRSPGM--EKLNALRYPPQSPRRLRMLLVAMEAQGCSCTLL
310 320 330 340 350
>>CCDS10389.1 ALDH1A3 gene_id:220|Hs108|chr15 (512 aa)
initn: 491 init1: 159 opt: 586 Z-score: 709.2 bits: 140.6 E(32554): 3.5e-33
Smith-Waterman score: 586; 28.2% identity (59.5% similar) in 444 aa overlap (4-431:71-506)
10 20 30
pF1KE4 MSKISEAVKRARAAFSSG---RTRPLQFRIQQL
...::. :..::. : : : . :
CCDS10 HESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSPWRRLDALSRGRLL
50 60 70 80 90 100
40 50 60 70 80 90
pF1KE4 EALQRLIQEQEQELVGALAADLHKNEWNAYYEEVVYVLEEIEYMIQKLPEWAADEPVEKT
. : :..... :.. . : : .:.. .. .. ..:. :: :. ::
CCDS10 HQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAG----WA-DKIQGKT
110 120 130 140 150
100 110 120 130 140
pF1KE4 PQTQQDEL-YIHSEPLGVVLVIGTWNYPFNLTIQPMVGAIAAGNAVVLKPSELSENMASL
:... . . . ::.:: .: ::.:. . . .. :. ::..::::.: . :
CCDS10 IPTDDNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQTPLTALY
160 170 180 190 200 210
150 160 170 180 190 200
pF1KE4 LATIIPQY-LDKDLYPVINGGVPETTELLKE--RFDHILYTGSTGVGKIIMTAAAK-HLT
:...: . . . .. : : . .. ....: .:::: :::.. ::.. .:
CCDS10 LGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAASRSNLK
220 230 240 250 260 270
210 220 230 240 250 260
pF1KE4 PVTLELGGKSPCYVDKNCDLDVACRRIAWGKFMNSGQTCVAPDYILCDPSIQNQIVEK-L
::::::::.:: : . :::.: . : :.:.:: :.: . .. . .. ...:.. .
CCDS10 RVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYSEFVRRSV
280 290 300 310 320 330
270 280 290 300 310
pF1KE4 KKSLKEFYGEDAKKSRDYGRIISARHFQRVMGLIE-----GQKVAYGGTG-DAATRYIAP
. . :. :. . . : :. ..:.... ::: : :. ::.. . .: :
CCDS10 EYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGSAMEDKGLFIKP
340 350 360 370 380 390
320 330 340 350 360 370
pF1KE4 TILTDVDPQSPVMQEEIFGPVLPIVCVRSLEEAIQFINQREKPLALYMFSSN-DKVIKKM
:....: . . .::::::: ::. .:.::.:. :. . :. .:..: ::..: .
CCDS10 TVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVFTKNLDKALK-L
400 410 420 430 440 450
380 390 400 410 420 430
pF1KE4 IAETSSGGVAANDVIVHITLHSLPFGGVGNSGMGSYHGKKSFETFSHRRSCLVRPLMNDE
. :: : : . . :::: :: : :. .. ... .. ..
CCDS10 ASALESGTVWIN--CYNALYAQAPFGGFKMSGNGRELGEYALAEYTEVKTVTIKLGDKNP
460 470 480 490 500 510
440 450
pF1KE4 GLKVRYPPSPAKMTQH
>>CCDS6644.1 ALDH1A1 gene_id:216|Hs108|chr9 (501 aa)
initn: 490 init1: 164 opt: 571 Z-score: 691.1 bits: 137.3 E(32554): 3.5e-32
Smith-Waterman score: 571; 29.5% identity (57.9% similar) in 444 aa overlap (4-431:60-495)
10 20 30
pF1KE4 MSKISEAVKRARAAFSSG---RTRPLQFRIQQL
...::: :: ::. : :: . : . :
CCDS66 HDSVSGKKFPVFNPATEEELCQVEEGDKEDVDKAVKAARQAFQIGSPWRTMDASERGRLL
30 40 50 60 70 80
40 50 60 70 80 90
pF1KE4 EALQRLIQEQEQELVGALAADLHKNEWNAYYEEVVYVLEEIEYMIQKLPEWAADEPVEKT
: ::.... :. . . : ::: .... .. ..: :: .
CCDS66 YKLADLIERDRLLLATMESMNGGKLYSNAYLNDLAGCIKTLRYCAG----WADKIQGRTI
90 100 110 120 130 140
100 110 120 130 140 150
pF1KE4 PQTQQDELYIHSEPLGVVLVIGTWNYPFNLTIQPMVGAIAAGNAVVLKPSELSENMASLL
: . : . ::.:: : ::.:. . : . :.. ::.::.::.: . : .
CCDS66 PIDGNFFTYTRHEPIGVCGQIIPWNFPLVMLIWKIGPALSCGNTVVVKPAEQTPLTALHV
150 160 170 180 190 200
160 170 180 190 200
pF1KE4 ATIIPQY-LDKDLYPVINGGVPETTELLKERFD--HILYTGSTGVGKIIMTAAAK-HLTP
:..: . . . .. : : . .. ..: .. .:::: :::.: ::.: .:
CCDS66 ASLIKEAGFPPGVVNIVPGYGPTAGAAISSHMDIDKVAFTGSTEVGKLIKEAAGKSNLKR
210 220 230 240 250 260
210 220 230 240 250 260
pF1KE4 VTLELGGKSPCYVDKNCDLDVACRRIAWGKFMNSGQTCVAPDYILCDPSIQNQIVEK-LK
::::::::::: : . ::: : . : :...:: :.: . :. . :: ...:.. ..
CCDS66 VTLELGGKSPCIVLADADLDNAVEFAHHGVFYHQGQCCIAASRIFVEESIYDEFVRRSVE
270 280 290 300 310 320
270 280 290 300 310
pF1KE4 KSLKEFYGEDAKKSRDYGRIISARHFQRVMGLIE-----GQKVAYGGTGDAATR--YIAP
.. : . :. . : :. ....... ::: : :. :: : ... .. :
CCDS66 RAKKYILGNPLTPGVTQGPQIDKEQYDKILDLIESGKKEGAKLECGG-GPWGNKGYFVQP
330 340 350 360 370 380
320 330 340 350 360 370
pF1KE4 TILTDVDPQSPVMQEEIFGPVLPIVCVRSLEEAIQFINQREKPLALYMFSSN-DKVIKKM
:....: . . .::::::: :. .::...:. :. :. .:... ::.: .
CCDS66 TVFSNVTDEMRIAKEEIFGPVQQIMKFKSLDDVIKRANNTFYGLSAGVFTKDIDKAIT-I
390 400 410 420 430 440
380 390 400 410 420 430
pF1KE4 IAETSSGGVAANDVIVHITLHSLPFGGVGNSGMGSYHGKKSFETFSHRRSCLVRPLMNDE
. ..: : .: .. . :::: :: : :. .:. ... .. :.
CCDS66 SSALQAGTVWVN--CYGVVSAQCPFGGFKMSGNGRELGEYGFHEYTEVKTVTVKISQKNS
450 460 470 480 490 500
440 450
pF1KE4 GLKVRYPPSPAKMTQH
453 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 17:40:28 2016 done: Mon Nov 7 17:40:29 2016
Total Scan time: 2.570 Total Display time: 0.070
Function used was FASTA [36.3.4 Apr, 2011]