Result of FASTA (omim) for
pFN21AE4427
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE4427, 444 aa
1>>>pF1KE4427 444 - 444 aa - 444 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.1670+/-0.00042; mu= 17.7994+/- 0.026
mean_var=62.4814+/-12.380, 0's: 0 Z-trim(111.4): 45 B-trim: 262 in 1/49
Lambda= 0.162255
statistics sampled from 19905 (19947) to 19905 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.591), E-opt: 0.2 (0.234), width: 16
Scan time: 8.430
The best scores are: opt bits E(85289)
NP_037534 (OMIM: 606148) fatty acid desaturase 1 [ ( 501) 3127 741.0 1.7e-213
XP_011543324 (OMIM: 606148) PREDICTED: fatty acid ( 430) 2652 629.8 4.3e-180
NP_004256 (OMIM: 606149) fatty acid desaturase 2 i ( 444) 1973 470.8 3.1e-132
NP_001268431 (OMIM: 606149) fatty acid desaturase ( 413) 1748 418.1 2.1e-116
NP_001268430 (OMIM: 606149) fatty acid desaturase ( 422) 1745 417.4 3.5e-116
NP_068373 (OMIM: 606150) fatty acid desaturase 3 [ ( 445) 1670 399.9 7e-111
XP_011543325 (OMIM: 606150) PREDICTED: fatty acid ( 454) 1633 391.2 2.9e-108
XP_016873213 (OMIM: 606150) PREDICTED: fatty acid ( 491) 1474 354.0 4.9e-97
XP_016873212 (OMIM: 606150) PREDICTED: fatty acid ( 500) 1172 283.4 9.5e-76
NP_085056 (OMIM: 611964) cytochrome b5 type B [Hom ( 150) 198 55.1 1.5e-07
NP_001905 (OMIM: 250790,613218) cytochrome b5 isof ( 98) 183 51.5 1.2e-06
XP_011524137 (OMIM: 250790,613218) PREDICTED: cyto ( 98) 183 51.5 1.2e-06
NP_001177736 (OMIM: 250790,613218) cytochrome b5 i ( 124) 184 51.8 1.2e-06
NP_683725 (OMIM: 250790,613218) cytochrome b5 isof ( 134) 183 51.5 1.6e-06
XP_011521619 (OMIM: 611026,612319) PREDICTED: fatt ( 369) 147 43.3 0.0013
NP_077282 (OMIM: 611026,612319) fatty acid 2-hydro ( 372) 147 43.3 0.0013
NP_001027558 (OMIM: 272300,606887) sulfite oxidase ( 545) 147 43.4 0.0017
XP_016875396 (OMIM: 272300,606887) PREDICTED: sulf ( 545) 147 43.4 0.0017
NP_000447 (OMIM: 272300,606887) sulfite oxidase, m ( 545) 147 43.4 0.0017
NP_001027559 (OMIM: 272300,606887) sulfite oxidase ( 545) 147 43.4 0.0017
XP_016875397 (OMIM: 272300,606887) PREDICTED: sulf ( 545) 147 43.4 0.0017
XP_016875395 (OMIM: 272300,606887) PREDICTED: sulf ( 552) 147 43.4 0.0018
XP_005269169 (OMIM: 272300,606887) PREDICTED: sulf ( 552) 147 43.4 0.0018
XP_016875394 (OMIM: 272300,606887) PREDICTED: sulf ( 552) 147 43.4 0.0018
>>NP_037534 (OMIM: 606148) fatty acid desaturase 1 [Homo (501 aa)
initn: 3127 init1: 3127 opt: 3127 Z-score: 3954.1 bits: 741.0 E(85289): 1.7e-213
Smith-Waterman score: 3127; 99.8% identity (99.8% similar) in 444 aa overlap (1-444:58-501)
10 20 30
pF1KE4 MAPDPVAAETAAQGPTPRYFTWDEVAQRSG
::::::::::::::::::::::::::::::
NP_037 RQQIHSWSPRTPSTRLTAPAGPARGVARPAMAPDPVAAETAAQGPTPRYFTWDEVAQRSG
30 40 50 60 70 80
40 50 60 70 80 90
pF1KE4 CEERWLVIDRKVYNISEFTRRHPGGSRVISHYAGQDATDPFVAFHINKGLVKKYMNSLLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 CEERWLVIDRKVYNISEFTRRHPGGSRVISHYAGQDATDPFVAFHINKGLVKKYMNSLLI
90 100 110 120 130 140
100 110 120 130 140 150
pF1KE4 GELSPEQPSFEPTKNKELTDEFRELRATVERMGLMKANHVFFLLYLLHILLLDGAAWLTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 GELSPEQPSFEPTKNKELTDEFRELRATVERMGLMKANHVFFLLYLLHILLLDGAAWLTL
150 160 170 180 190 200
160 170 180 190 200 210
pF1KE4 WVFGTSFLPFLLCAVLLSAVQAQAGWLQHDFGHLSVFSTSKWNHLLHHFVIGHLKGAPAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 WVFGTSFLPFLLCAVLLSAVQAQAGWLQHDFGHLSVFSTSKWNHLLHHFVIGHLKGAPAS
210 220 230 240 250 260
220 230 240 250 260 270
pF1KE4 WWNHMHFQHHAKPNCFRKDPDINMHPFFFALGKILSVELGKQKKKYMPYNHQHKYFFLIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 WWNHMHFQHHAKPNCFRKDPDINMHPFFFALGKILSVELGKQKKKYMPYNHQHKYFFLIG
270 280 290 300 310 320
280 290 300 310 320 330
pF1KE4 PSALLPLYFQWYIFYFVIQRKKWVDLAWMITFYVRFFLTYVPLLGLKAFLGLFFIVRFLE
: ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 PPALLPLYFQWYIFYFVIQRKKWVDLAWMITFYVRFFLTYVPLLGLKAFLGLFFIVRFLE
330 340 350 360 370 380
340 350 360 370 380 390
pF1KE4 SNWFVWVTQMNHIPMHIDHDRNMDWVSTQLQATCNVHKSAFNDWFSGHLNFQIEHHLFPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 SNWFVWVTQMNHIPMHIDHDRNMDWVSTQLQATCNVHKSAFNDWFSGHLNFQIEHHLFPT
390 400 410 420 430 440
400 410 420 430 440
pF1KE4 MPRHNYHKVAPLVQSLCAKHGIEYQSKPLLSAFADIIHSLKESGQLWLDAYLHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 MPRHNYHKVAPLVQSLCAKHGIEYQSKPLLSAFADIIHSLKESGQLWLDAYLHQ
450 460 470 480 490 500
>>XP_011543324 (OMIM: 606148) PREDICTED: fatty acid desa (430 aa)
initn: 2652 init1: 2652 opt: 2652 Z-score: 3354.2 bits: 629.8 E(85289): 4.3e-180
Smith-Waterman score: 2652; 99.7% identity (99.7% similar) in 376 aa overlap (69-444:55-430)
40 50 60 70 80 90
pF1KE4 DRKVYNISEFTRRHPGGSRVISHYAGQDATDPFVAFHINKGLVKKYMNSLLIGELSPEQP
::::::::::::::::::::::::::::::
XP_011 PTRRITYRARGCRTCQRESYRHGPYLAQPKDPFVAFHINKGLVKKYMNSLLIGELSPEQP
30 40 50 60 70 80
100 110 120 130 140 150
pF1KE4 SFEPTKNKELTDEFRELRATVERMGLMKANHVFFLLYLLHILLLDGAAWLTLWVFGTSFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SFEPTKNKELTDEFRELRATVERMGLMKANHVFFLLYLLHILLLDGAAWLTLWVFGTSFL
90 100 110 120 130 140
160 170 180 190 200 210
pF1KE4 PFLLCAVLLSAVQAQAGWLQHDFGHLSVFSTSKWNHLLHHFVIGHLKGAPASWWNHMHFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PFLLCAVLLSAVQAQAGWLQHDFGHLSVFSTSKWNHLLHHFVIGHLKGAPASWWNHMHFQ
150 160 170 180 190 200
220 230 240 250 260 270
pF1KE4 HHAKPNCFRKDPDINMHPFFFALGKILSVELGKQKKKYMPYNHQHKYFFLIGPSALLPLY
::::::::::::::::::::::::::::::::::::::::::::::::::::: ::::::
XP_011 HHAKPNCFRKDPDINMHPFFFALGKILSVELGKQKKKYMPYNHQHKYFFLIGPPALLPLY
210 220 230 240 250 260
280 290 300 310 320 330
pF1KE4 FQWYIFYFVIQRKKWVDLAWMITFYVRFFLTYVPLLGLKAFLGLFFIVRFLESNWFVWVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FQWYIFYFVIQRKKWVDLAWMITFYVRFFLTYVPLLGLKAFLGLFFIVRFLESNWFVWVT
270 280 290 300 310 320
340 350 360 370 380 390
pF1KE4 QMNHIPMHIDHDRNMDWVSTQLQATCNVHKSAFNDWFSGHLNFQIEHHLFPTMPRHNYHK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QMNHIPMHIDHDRNMDWVSTQLQATCNVHKSAFNDWFSGHLNFQIEHHLFPTMPRHNYHK
330 340 350 360 370 380
400 410 420 430 440
pF1KE4 VAPLVQSLCAKHGIEYQSKPLLSAFADIIHSLKESGQLWLDAYLHQ
::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VAPLVQSLCAKHGIEYQSKPLLSAFADIIHSLKESGQLWLDAYLHQ
390 400 410 420 430
>>NP_004256 (OMIM: 606149) fatty acid desaturase 2 isofo (444 aa)
initn: 2017 init1: 1019 opt: 1973 Z-score: 2495.0 bits: 470.8 E(85289): 3.1e-132
Smith-Waterman score: 1973; 63.1% identity (83.8% similar) in 439 aa overlap (7-444:11-444)
10 20 30 40 50
pF1KE4 MAPDPVAAETAAQGPTPRYFTWDEVAQRSGCEERWLVIDRKVYNISEFTRRHPGGS
::: .. :: :.:.:. ... .::::::::::::.... .::::.
NP_004 MGKGGNQGEGAAEREVSVPT---FSWEEIQKHNLRTDRWLVIDRKVYNITKWSIQHPGGQ
10 20 30 40 50
60 70 80 90 100 110
pF1KE4 RVISHYAGQDATDPFVAFHINKGLVKKYMNSLLIGELSPEQPSFEPTKNKELTDEFRELR
:::.::::.:::: : ::: . .: :... ::::::.::.:: . ::...:..:: ::
NP_004 RVIGHYAGEDATDAFRAFHPDLEFVGKFLKPLLIGELAPEEPSQDHGKNSKITEDFRALR
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE4 ATVERMGLMKANHVFFLLYLLHILLLDGAAWLTLWVFGTSFLPFLLCAVLLSAVQAQAGW
:.: :.:.:.::::::: : ::. :.. ::.:.. ::....: :. : .:.. ::::::
NP_004 KTAEDMNLFKTNHVFFLLLLAHIIALESIAWFTVFYFGNGWIPTLITAFVLATSQAQAGW
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE4 LQHDFGHLSVFSTSKWNHLLHHFVIGHLKGAPASWWNHMHFQHHAKPNCFRKDPDINMHP
::::.:::::. :::::.:.::::::::: :.:::: ::::::::: :.::::.::
NP_004 LQHDYGHLSVYRKPKWNHLVHKFVIGHLKGASANWWNHRHFQHHAKPNIFHKDPDVNML-
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE4 FFFALGKILSVELGKQKKKYMPYNHQHKYFFLIGPSALLPLYFQWYIFYFVIQRKKWVDL
:.::. .: ::.: ::.::::::.::::::: :.:.:::. :.. .: .:.::::
NP_004 HVFVLGEWQPIEYGKKKLKYLPYNHQHEYFFLIGPPLLIPMYFQYQIIMTMIVHKNWVDL
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE4 AWMITFYVRFFLTYVPLLG-LKAFLGLFFIVRFLESNWFVWVTQMNHIPMHIDHDRNMDW
:: ...:.:::.::.:. : : :.: : :: :::::.::::::::::: :.::.. ::
NP_004 AWAVSYYIRFFITYIPFYGILGALLFLNFI-RFLESHWFVWVTQMNHIVMEIDQEAYRDW
300 310 320 330 340 350
360 370 380 390 400 410
pF1KE4 VSTQLQATCNVHKSAFNDWFSGHLNFQIEHHLFPTMPRHNYHKVAPLVQSLCAKHGIEYQ
:.:: :::::..: ::::::::::::::::::::::::: ::.::::.:::::::::::
NP_004 FSSQLTATCNVEQSFFNDWFSGHLNFQIEHHLFPTMPRHNLHKIAPLVKSLCAKHGIEYQ
360 370 380 390 400 410
420 430 440
pF1KE4 SKPLLSAFADIIHSLKESGQLWLDAYLHQ
:::: :. :::.:::.::.::::::::.
NP_004 EKPLLRALLDIIRSLKKSGKLWLDAYLHK
420 430 440
>>NP_001268431 (OMIM: 606149) fatty acid desaturase 2 is (413 aa)
initn: 1849 init1: 1019 opt: 1748 Z-score: 2210.8 bits: 418.1 E(85289): 2.1e-116
Smith-Waterman score: 1748; 61.4% identity (81.4% similar) in 409 aa overlap (40-444:9-413)
10 20 30 40 50 60
pF1KE4 TAAQGPTPRYFTWDEVAQRSGCEERWLVIDRKVYNISEFTRRHPGGSRVISHYA--GQDA
:.: .. .: : . : :: . ..
NP_001 MTREPPGCRRVNSLMLYTLRSITSHRS-SHPERWATSS
10 20 30
70 80 90 100 110 120
pF1KE4 TDPFVAFHINKGLVKKYMNSLLIGELSPEQPSFEPTKNKELTDEFRELRATVERMGLMKA
: : ::: . .: :... ::::::.::.:: . ::...:..:: :: :.: :.:.:.
NP_001 QDAFRAFHPDLEFVGKFLKPLLIGELAPEEPSQDHGKNSKITEDFRALRKTAEDMNLFKT
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE4 NHVFFLLYLLHILLLDGAAWLTLWVFGTSFLPFLLCAVLLSAVQAQAGWLQHDFGHLSVF
::::::: : ::. :.. ::.:.. ::....: :. : .:.. ::::::::::.:::::.
NP_001 NHVFFLLLLAHIIALESIAWFTVFYFGNGWIPTLITAFVLATSQAQAGWLQHDYGHLSVY
100 110 120 130 140 150
190 200 210 220 230 240
pF1KE4 STSKWNHLLHHFVIGHLKGAPASWWNHMHFQHHAKPNCFRKDPDINM-HPFFFALGKILS
:::::.:.::::::::: :.:::: ::::::::: :.::::.:: : :.::.
NP_001 RKPKWNHLVHKFVIGHLKGASANWWNHRHFQHHAKPNIFHKDPDVNMLH--VFVLGEWQP
160 170 180 190 200 210
250 260 270 280 290 300
pF1KE4 VELGKQKKKYMPYNHQHKYFFLIGPSALLPLYFQWYIFYFVIQRKKWVDLAWMITFYVRF
.: ::.: ::.::::::.::::::: :.:.:::. :.. .: .:.:::::: ...:.::
NP_001 IEYGKKKLKYLPYNHQHEYFFLIGPPLLIPMYFQYQIIMTMIVHKNWVDLAWAVSYYIRF
220 230 240 250 260 270
310 320 330 340 350 360
pF1KE4 FLTYVPLLG-LKAFLGLFFIVRFLESNWFVWVTQMNHIPMHIDHDRNMDWVSTQLQATCN
:.::.:. : : :.: : :: :::::.::::::::::: :.::.. :: :.:: ::::
NP_001 FITYIPFYGILGALLFLNFI-RFLESHWFVWVTQMNHIVMEIDQEAYRDWFSSQLTATCN
280 290 300 310 320 330
370 380 390 400 410 420
pF1KE4 VHKSAFNDWFSGHLNFQIEHHLFPTMPRHNYHKVAPLVQSLCAKHGIEYQSKPLLSAFAD
:..: ::::::::::::::::::::::::: ::.::::.::::::::::: :::: :. :
NP_001 VEQSFFNDWFSGHLNFQIEHHLFPTMPRHNLHKIAPLVKSLCAKHGIEYQEKPLLRALLD
340 350 360 370 380 390
430 440
pF1KE4 IIHSLKESGQLWLDAYLHQ
::.:::.::.::::::::.
NP_001 IIRSLKKSGKLWLDAYLHK
400 410
>>NP_001268430 (OMIM: 606149) fatty acid desaturase 2 is (422 aa)
initn: 1825 init1: 1019 opt: 1745 Z-score: 2206.9 bits: 417.4 E(85289): 3.5e-116
Smith-Waterman score: 1745; 62.9% identity (83.1% similar) in 396 aa overlap (52-444:35-422)
30 40 50 60 70 80
pF1KE4 WDEVAQRSGCEERWLVIDRKVYNISEFTRRHPGGSRVISH-YAGQDATDPFVAFHINKGL
::... .: .::. : : ::: . .
NP_001 EAGPFVCVCVLLASIPTPQTPLLQASLPPFHPASA---GHPITGQQ--DAFRAFHPDLEF
10 20 30 40 50
90 100 110 120 130 140
pF1KE4 VKKYMNSLLIGELSPEQPSFEPTKNKELTDEFRELRATVERMGLMKANHVFFLLYLLHIL
: :... ::::::.::.:: . ::...:..:: :: :.: :.:.:.::::::: : ::.
NP_001 VGKFLKPLLIGELAPEEPSQDHGKNSKITEDFRALRKTAEDMNLFKTNHVFFLLLLAHII
60 70 80 90 100 110
150 160 170 180 190 200
pF1KE4 LLDGAAWLTLWVFGTSFLPFLLCAVLLSAVQAQAGWLQHDFGHLSVFSTSKWNHLLHHFV
:.. ::.:.. ::....: :. : .:.. ::::::::::.:::::. :::::.:.::
NP_001 ALESIAWFTVFYFGNGWIPTLITAFVLATSQAQAGWLQHDYGHLSVYRKPKWNHLVHKFV
120 130 140 150 160 170
210 220 230 240 250
pF1KE4 IGHLKGAPASWWNHMHFQHHAKPNCFRKDPDINM-HPFFFALGKILSVELGKQKKKYMPY
::::::: :.:::: ::::::::: :.::::.:: : :.::. .: ::.: ::.::
NP_001 IGHLKGASANWWNHRHFQHHAKPNIFHKDPDVNMLH--VFVLGEWQPIEYGKKKLKYLPY
180 190 200 210 220 230
260 270 280 290 300 310
pF1KE4 NHQHKYFFLIGPSALLPLYFQWYIFYFVIQRKKWVDLAWMITFYVRFFLTYVPLLG-LKA
::::.::::::: :.:.:::. :.. .: .:.:::::: ...:.:::.::.:. : : :
NP_001 NHQHEYFFLIGPPLLIPMYFQYQIIMTMIVHKNWVDLAWAVSYYIRFFITYIPFYGILGA
240 250 260 270 280 290
320 330 340 350 360 370
pF1KE4 FLGLFFIVRFLESNWFVWVTQMNHIPMHIDHDRNMDWVSTQLQATCNVHKSAFNDWFSGH
.: : :: :::::.::::::::::: :.::.. :: :.:: :::::..: ::::::::
NP_001 LLFLNFI-RFLESHWFVWVTQMNHIVMEIDQEAYRDWFSSQLTATCNVEQSFFNDWFSGH
300 310 320 330 340 350
380 390 400 410 420 430
pF1KE4 LNFQIEHHLFPTMPRHNYHKVAPLVQSLCAKHGIEYQSKPLLSAFADIIHSLKESGQLWL
::::::::::::::::: ::.::::.::::::::::: :::: :. :::.:::.::.:::
NP_001 LNFQIEHHLFPTMPRHNLHKIAPLVKSLCAKHGIEYQEKPLLRALLDIIRSLKKSGKLWL
360 370 380 390 400 410
440
pF1KE4 DAYLHQ
:::::.
NP_001 DAYLHK
420
>>NP_068373 (OMIM: 606150) fatty acid desaturase 3 [Homo (445 aa)
initn: 1708 init1: 911 opt: 1670 Z-score: 2111.7 bits: 399.9 E(85289): 7e-111
Smith-Waterman score: 1670; 52.3% identity (78.1% similar) in 442 aa overlap (3-444:7-445)
10 20 30 40 50
pF1KE4 MAPDPVAAETAAQGPTPRYFTWDEVAQRSGCEERWLVIDRKVYNISEFTRRHPGGS
: : . . .: : : :... .. ..::::.:.::.::....::::::
NP_068 MGGVGEPGPREGPAQPGAPLPT-FCWEQIRAHDQPGDKWLVIERRVYDISRWAQRHPGGS
10 20 30 40 50
60 70 80 90 100 110
pF1KE4 RVISHYAGQDATDPFVAFHINKGLVKKYMNSLLIGELSPEQPSFEPTKNKELTDEFRELR
:.:.:....:::: : ::: . ..:.:... ::::::.::.:: . : .:...:: :.
NP_068 RLIGHHGAEDATDAFRAFHQDLNFVRKFLQPLLIGELAPEEPSQDGPLNAQLVEDFRALH
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE4 ATVERMGLMKANHVFFLLYLLHILLLDGAAWLTLWVFGTSFLPFLLCAVLLSAVQAQAGW
..: : :. :. .:: . : ::: .. ::: ....: ...: : : .:. :::.
NP_068 QAAEDMKLFDASPTFFAFLLGHILAMEVLAWLLIYLLGPGWVPSALAAFILAISQAQSWC
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE4 LQHDFGHLSVFSTSKWNHLLHHFVIGHLKGAPASWWNHMHFQHHAKPNCFRKDPDINMHP
::::.:: :.:. : :::. ..::.:.::: : ::: ::::::::: :.::::... :
NP_068 LQHDLGHASIFKKSWWNHVAQKFVMGQLKGFSAHWWNFRHFQHHAKPNIFHKDPDVTVAP
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE4 FFFALGKILSVELGKQKKKYMPYNHQHKYFFLIGPSALLPLYFQWYIFYFVIQRKKWVDL
:. ::. ::: ::.:..:.:::.:: ::::::: : . :. . ... .:.::
NP_068 VFL-LGES-SVEYGKKKRRYLPYNQQHLYFFLIGPPLLTLVNFEVENLAYMLVCMQWADL
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE4 AWMITFYVRFFLTYVPLLGLKAFLGLFFIVRFLESNWFVWVTQMNHIPMHIDHDRNMDWV
: .::.::::.:.:. :. . : .: :: :::.::::.::::::: .: :... :::
NP_068 LWAASFYARFFLSYLPFYGVPGVLLFFVAVRVLESHWFVWITQMNHIPKEIGHEKHRDWV
300 310 320 330 340 350
360 370 380 390 400 410
pF1KE4 STQLQATCNVHKSAFNDWFSGHLNFQIEHHLFPTMPRHNYHKVAPLVQSLCAKHGIEYQS
:.:: :::::. : :..:::::::::::::::: :::::: .:::::.:::::::. :.
NP_068 SSQLAATCNVEPSLFTNWFSGHLNFQIEHHLFPRMPRHNYSRVAPLVKSLCAKHGLSYEV
360 370 380 390 400 410
420 430 440
pF1KE4 KPLLSAFADIIHSLKESGQLWLDAYLHQ
::.:.:..::..:::.::..::::::::
NP_068 KPFLTALVDIVRSLKKSGDIWLDAYLHQ
420 430 440
>>XP_011543325 (OMIM: 606150) PREDICTED: fatty acid desa (454 aa)
initn: 1714 init1: 733 opt: 1633 Z-score: 2064.7 bits: 391.2 E(85289): 2.9e-108
Smith-Waterman score: 1633; 51.0% identity (76.5% similar) in 451 aa overlap (3-444:7-454)
10 20 30 40 50
pF1KE4 MAPDPVAAETAAQGPTPRYFTWDEVAQRSGCEERWLVIDRKVYNISEFTRRHPGGS
: : . . .: : : :... .. ..::::.:.::.::....::::::
XP_011 MGGVGEPGPREGPAQPGAPLPT-FCWEQIRAHDQPGDKWLVIERRVYDISRWAQRHPGGS
10 20 30 40 50
60 70 80 90 100 110
pF1KE4 RVISHYAGQDATDPFVAFHINKGLVKKYMNSLLIGELSPEQPSFEPTKNKELTDEFRELR
:.:.:....:::: : ::: . ..:.:... ::::::.::.:: . : .:...:: :.
XP_011 RLIGHHGAEDATDAFRAFHQDLNFVRKFLQPLLIGELAPEEPSQDGPLNAQLVEDFRALH
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE4 ATVERMGLMKANHVFFLLYLLHILLLDGAAWLTLWVFGTSFLPFLLCAVLLSAVQAQAGW
..: : :. :. .:: . : ::: .. ::: ....: ...: : : .:. :::.
XP_011 QAAEDMKLFDASPTFFAFLLGHILAMEVLAWLLIYLLGPGWVPSALAAFILAISQAQSWC
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE4 LQHDFGHLSVFSTSKWNHLLHHFVIGHLKGAPASWWNHMHFQHHAKPNCFRKDPDINMHP
::::.:: :.:. : :::. ..::.:.::: : ::: ::::::::: :.::::... :
XP_011 LQHDLGHASIFKKSWWNHVAQKFVMGQLKGFSAHWWNFRHFQHHAKPNIFHKDPDVTVAP
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE4 FFFALGKILSVELGKQKKKYMPYNHQHKYFFLIGPSALLPLYFQWYIFYFVIQRKKWVDL
:. ::. ::: ::.:..:.:::.:: ::::::: : . :. . ... .:.::
XP_011 VFL-LGES-SVEYGKKKRRYLPYNQQHLYFFLIGPPLLTLVNFEVENLAYMLVCMQWADL
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE4 AWMITFYVRFFLTYVPLLGLKAFLGLFFIVRFLESNWFVWVTQMNHIPMHIDHDRNMDWV
: .::.::::.:.:. :. . : .: :: :::.::::.::::::: .: :... :::
XP_011 LWAASFYARFFLSYLPFYGVPGVLLFFVAVRVLESHWFVWITQMNHIPKEIGHEKHRDWV
300 310 320 330 340 350
360 370 380 390 400
pF1KE4 STQLQATCNVHKSAFNDWFSGHLNFQIEHH---------LFPTMPRHNYHKVAPLVQSLC
:.:: :::::. : :..::::::::::::. ::: :::::: .:::::.:::
XP_011 SSQLAATCNVEPSLFTNWFSGHLNFQIEHQCQHTLPTPSLFPRMPRHNYSRVAPLVKSLC
360 370 380 390 400 410
410 420 430 440
pF1KE4 AKHGIEYQSKPLLSAFADIIHSLKESGQLWLDAYLHQ
::::. :. ::.:.:..::..:::.::..::::::::
XP_011 AKHGLSYEVKPFLTALVDIVRSLKKSGDIWLDAYLHQ
420 430 440 450
>>XP_016873213 (OMIM: 606150) PREDICTED: fatty acid desa (491 aa)
initn: 1547 init1: 911 opt: 1474 Z-score: 1863.1 bits: 354.0 E(85289): 4.9e-97
Smith-Waterman score: 1474; 53.3% identity (77.3% similar) in 396 aa overlap (50-444:99-491)
20 30 40 50 60 70
pF1KE4 FTWDEVAQRSGCEERWLVIDRKVYNISEFTRRHPGGSRVISHYAGQDAT-DPFVAFHINK
: .::: .. : .:: : : ::: .
XP_016 PRDSVPPLGALDLTLQDARLEAPQAPLLTDRDSASGSRGRGE-ALRDAQQDAFRAFHQDL
70 80 90 100 110 120
80 90 100 110 120 130
pF1KE4 GLVKKYMNSLLIGELSPEQPSFEPTKNKELTDEFRELRATVERMGLMKANHVFFLLYLLH
..:.:... ::::::.::.:: . : .:...:: :. ..: : :. :. .:: . : :
XP_016 NFVRKFLQPLLIGELAPEEPSQDGPLNAQLVEDFRALHQAAEDMKLFDASPTFFAFLLGH
130 140 150 160 170 180
140 150 160 170 180 190
pF1KE4 ILLLDGAAWLTLWVFGTSFLPFLLCAVLLSAVQAQAGWLQHDFGHLSVFSTSKWNHLLHH
:: .. ::: ....: ...: : : .:. :::. ::::.:: :.:. : :::. ..
XP_016 ILAMEVLAWLLIYLLGPGWVPSALAAFILAISQAQSWCLQHDLGHASIFKKSWWNHVAQK
190 200 210 220 230 240
200 210 220 230 240 250
pF1KE4 FVIGHLKGAPASWWNHMHFQHHAKPNCFRKDPDINMHPFFFALGKILSVELGKQKKKYMP
::.:.::: : ::: ::::::::: :.::::... : :. ::. ::: ::.:..:.:
XP_016 FVMGQLKGFSAHWWNFRHFQHHAKPNIFHKDPDVTVAPVFL-LGES-SVEYGKKKRRYLP
250 260 270 280 290 300
260 270 280 290 300 310
pF1KE4 YNHQHKYFFLIGPSALLPLYFQWYIFYFVIQRKKWVDLAWMITFYVRFFLTYVPLLGLKA
::.:: ::::::: : . :. . ... .:.:: : .::.::::.:.:. :. .
XP_016 YNQQHLYFFLIGPPLLTLVNFEVENLAYMLVCMQWADLLWAASFYARFFLSYLPFYGVPG
310 320 330 340 350 360
320 330 340 350 360 370
pF1KE4 FLGLFFIVRFLESNWFVWVTQMNHIPMHIDHDRNMDWVSTQLQATCNVHKSAFNDWFSGH
: .: :: :::.::::.::::::: .: :... ::::.:: :::::. : :..:::::
XP_016 VLLFFVAVRVLESHWFVWITQMNHIPKEIGHEKHRDWVSSQLAATCNVEPSLFTNWFSGH
370 380 390 400 410 420
380 390 400 410 420 430
pF1KE4 LNFQIEHHLFPTMPRHNYHKVAPLVQSLCAKHGIEYQSKPLLSAFADIIHSLKESGQLWL
::::::::::: :::::: .:::::.:::::::. :. ::.:.:..::..:::.::..::
XP_016 LNFQIEHHLFPRMPRHNYSRVAPLVKSLCAKHGLSYEVKPFLTALVDIVRSLKKSGDIWL
430 440 450 460 470 480
440
pF1KE4 DAYLHQ
::::::
XP_016 DAYLHQ
490
>>XP_016873212 (OMIM: 606150) PREDICTED: fatty acid desa (500 aa)
initn: 1553 init1: 594 opt: 1172 Z-score: 1480.9 bits: 283.4 E(85289): 9.5e-76
Smith-Waterman score: 1437; 51.9% identity (75.6% similar) in 405 aa overlap (50-444:99-500)
20 30 40 50 60 70
pF1KE4 FTWDEVAQRSGCEERWLVIDRKVYNISEFTRRHPGGSRVISHYAGQDAT-DPFVAFHINK
: .::: .. : .:: : : ::: .
XP_016 PRDSVPPLGALDLTLQDARLEAPQAPLLTDRDSASGSRGRGE-ALRDAQQDAFRAFHQDL
70 80 90 100 110 120
80 90 100 110 120 130
pF1KE4 GLVKKYMNSLLIGELSPEQPSFEPTKNKELTDEFRELRATVERMGLMKANHVFFLLYLLH
..:.:... ::::::.::.:: . : .:...:: :. ..: : :. :. .:: . : :
XP_016 NFVRKFLQPLLIGELAPEEPSQDGPLNAQLVEDFRALHQAAEDMKLFDASPTFFAFLLGH
130 140 150 160 170 180
140 150 160 170 180 190
pF1KE4 ILLLDGAAWLTLWVFGTSFLPFLLCAVLLSAVQAQAGWLQHDFGHLSVFSTSKWNHLLHH
:: .. ::: ....: ...: : : .:. :::. ::::.:: :.:. : :::. ..
XP_016 ILAMEVLAWLLIYLLGPGWVPSALAAFILAISQAQSWCLQHDLGHASIFKKSWWNHVAQK
190 200 210 220 230 240
200 210 220 230 240 250
pF1KE4 FVIGHLKGAPASWWNHMHFQHHAKPNCFRKDPDINMHPFFFALGKILSVELGKQKKKYMP
::.:.::: : ::: ::::::::: :.::::... : :. ::. ::: ::.:..:.:
XP_016 FVMGQLKGFSAHWWNFRHFQHHAKPNIFHKDPDVTVAPVFL-LGES-SVEYGKKKRRYLP
250 260 270 280 290 300
260 270 280 290 300 310
pF1KE4 YNHQHKYFFLIGPSALLPLYFQWYIFYFVIQRKKWVDLAWMITFYVRFFLTYVPLLGLKA
::.:: ::::::: : . :. . ... .:.:: : .::.::::.:.:. :. .
XP_016 YNQQHLYFFLIGPPLLTLVNFEVENLAYMLVCMQWADLLWAASFYARFFLSYLPFYGVPG
310 320 330 340 350 360
320 330 340 350 360 370
pF1KE4 FLGLFFIVRFLESNWFVWVTQMNHIPMHIDHDRNMDWVSTQLQATCNVHKSAFNDWFSGH
: .: :: :::.::::.::::::: .: :... ::::.:: :::::. : :..:::::
XP_016 VLLFFVAVRVLESHWFVWITQMNHIPKEIGHEKHRDWVSSQLAATCNVEPSLFTNWFSGH
370 380 390 400 410 420
380 390 400 410 420
pF1KE4 LNFQIEHH---------LFPTMPRHNYHKVAPLVQSLCAKHGIEYQSKPLLSAFADIIHS
:::::::. ::: :::::: .:::::.:::::::. :. ::.:.:..::..:
XP_016 LNFQIEHQCQHTLPTPSLFPRMPRHNYSRVAPLVKSLCAKHGLSYEVKPFLTALVDIVRS
430 440 450 460 470 480
430 440
pF1KE4 LKESGQLWLDAYLHQ
::.::..::::::::
XP_016 LKKSGDIWLDAYLHQ
490 500
>>NP_085056 (OMIM: 611964) cytochrome b5 type B [Homo sa (150 aa)
initn: 191 init1: 156 opt: 198 Z-score: 256.5 bits: 55.1 E(85289): 1.5e-07
Smith-Waterman score: 198; 36.3% identity (71.4% similar) in 91 aa overlap (19-105:26-116)
10 20 30 40 50
pF1KE4 MAPDPVAAETAAQGPTPRYFTWDEVAQRSGCEERWLVIDRKVYNISEFTRRHP
:. .:::.:.. .: :::: .::....: .::
NP_085 MSGSMATAEASGSDGKGQEVETSVTYYRLEEVAKRNSLKELWLVIHGRVYDVTRFLNEHP
10 20 30 40 50 60
60 70 80 90 100
pF1KE4 GGSRVISHYAGQDATDPFVAF-HIN--KGLVKKY-MNSLLIGELSPEQPSFEPTKNKELT
:: .:. . :: ::.. : : . . ..:.: .... ..:.::. : .:.::
NP_085 GGEEVLLEQAGVDASESFEDVGHSSDAREMLKQYYIGDIHPSDLKPESGSKDPSKNDTCK
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE4 DEFRELRATVERMGLMKANHVFFLLYLLHILLLDGAAWLTLWVFGTSFLPFLLCAVLLSA
NP_085 SCWAYWILPIIGAVLLGFLYRYYTSESKSS
130 140 150
444 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 00:40:59 2016 done: Sun Nov 6 00:41:00 2016
Total Scan time: 8.430 Total Display time: 0.070
Function used was FASTA [36.3.4 Apr, 2011]