Result of FASTA (omim) for
pFN21AE4425
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE4425, 440 aa
1>>>pF1KE4425 440 - 440 aa - 440 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.6313+/-0.000348; mu= 15.4130+/- 0.022
mean_var=65.4414+/-13.176, 0's: 0 Z-trim(113.8): 44 B-trim: 285 in 1/56
Lambda= 0.158543
statistics sampled from 23328 (23372) to 23328 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.641), E-opt: 0.2 (0.274), width: 16
Scan time: 9.550
The best scores are: opt bits E(85289)
NP_005733 (OMIM: 611099) protein disulfide-isomera ( 440) 2954 684.6 1.4e-196
NP_001269636 (OMIM: 611099) protein disulfide-isom ( 437) 2934 680.0 3.3e-195
NP_001269635 (OMIM: 611099) protein disulfide-isom ( 445) 2922 677.2 2.2e-194
NP_001269634 (OMIM: 611099) protein disulfide-isom ( 488) 2922 677.3 2.4e-194
NP_001269633 (OMIM: 611099) protein disulfide-isom ( 492) 2922 677.3 2.5e-194
XP_011508610 (OMIM: 611099) PREDICTED: protein dis ( 402) 2576 598.1 1.4e-170
NP_005304 (OMIM: 602046) protein disulfide-isomera ( 505) 310 79.8 1.8e-14
XP_011524337 (OMIM: 616102) PREDICTED: protein dis ( 229) 282 73.3 7.4e-13
XP_011524336 (OMIM: 616102) PREDICTED: protein dis ( 231) 282 73.3 7.5e-13
NP_061895 (OMIM: 616102) protein disulfide-isomera ( 454) 282 73.4 1.4e-12
NP_006801 (OMIM: 616942) protein disulfide-isomera ( 519) 281 73.2 1.8e-12
NP_110437 (OMIM: 616412) thioredoxin domain-contai ( 432) 259 68.1 5e-11
NP_001258510 (OMIM: 607987) dnaJ homolog subfamily ( 747) 248 65.7 4.7e-10
NP_061854 (OMIM: 607987) dnaJ homolog subfamily C ( 793) 248 65.7 4.9e-10
NP_110382 (OMIM: 610527) thioredoxin-related trans ( 280) 228 61.0 4.6e-09
NP_859052 (OMIM: 612860) sulfhydryl oxidase 2 prec ( 698) 228 61.1 1e-08
NP_001004128 (OMIM: 603120) sulfhydryl oxidase 1 i ( 604) 202 55.1 5.7e-07
NP_000909 (OMIM: 112240,176790) protein disulfide- ( 508) 201 54.9 5.7e-07
NP_002817 (OMIM: 603120) sulfhydryl oxidase 1 isof ( 747) 202 55.2 6.9e-07
NP_055866 (OMIM: 609170) endoplasmic reticulum res ( 406) 189 52.1 3.1e-06
NP_006840 (OMIM: 608012) protein disulfide-isomera ( 525) 183 50.8 1e-05
XP_006724289 (OMIM: 609063,616811) PREDICTED: thio ( 166) 156 44.4 0.00026
NP_036605 (OMIM: 609063,616811) thioredoxin, mitoc ( 166) 156 44.4 0.00026
XP_005261565 (OMIM: 609063,616811) PREDICTED: thio ( 197) 156 44.5 0.00031
NP_066979 (OMIM: 616766) thioredoxin-related trans ( 349) 141 41.1 0.0055
NP_001139021 (OMIM: 616412) thioredoxin domain-con ( 324) 139 40.6 0.0071
>>NP_005733 (OMIM: 611099) protein disulfide-isomerase A (440 aa)
initn: 2954 init1: 2954 opt: 2954 Z-score: 3650.3 bits: 684.6 E(85289): 1.4e-196
Smith-Waterman score: 2954; 100.0% identity (100.0% similar) in 440 aa overlap (1-440:1-440)
10 20 30 40 50 60
pF1KE4 MALLVLGLVSCTFFLAVNGLYSSSDDVIELTPSNFNREVIQSDSLWLVEFYAPWCGHCQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MALLVLGLVSCTFFLAVNGLYSSSDDVIELTPSNFNREVIQSDSLWLVEFYAPWCGHCQR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 LTPEWKKAATALKDVVKVGAVDADKHHSLGGQYGVQGFPTIKIFGSNKNRPEDYQGGRTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 LTPEWKKAATALKDVVKVGAVDADKHHSLGGQYGVQGFPTIKIFGSNKNRPEDYQGGRTG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 EAIVDAALSALRQLVKDRLGGRSGGYSSGKQGRSDSSSKKDVIELTDDSFDKNVLDSEDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 EAIVDAALSALRQLVKDRLGGRSGGYSSGKQGRSDSSSKKDVIELTDDSFDKNVLDSEDV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 WMVEFYAPWCGHCKNLEPEWAAAASEVKEQTKGKVKLAAVDATVNQVLASRYGIRGFPTI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 WMVEFYAPWCGHCKNLEPEWAAAASEVKEQTKGKVKLAAVDATVNQVLASRYGIRGFPTI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 KIFQKGESPVDYDGGRTRSDIVSRALDLFSDNAPPPELLEIINEDIAKRTCEEHQLCVVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 KIFQKGESPVDYDGGRTRSDIVSRALDLFSDNAPPPELLEIINEDIAKRTCEEHQLCVVA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 VLPHILDTGAAGRNSYLEVLLKLADKYKKKMWGWLWTEAGAQSELETALGIGGFGYPAMA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 VLPHILDTGAAGRNSYLEVLLKLADKYKKKMWGWLWTEAGAQSELETALGIGGFGYPAMA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 AINARKMKFALLKGSFSEQGINEFLRELSFGRGSTAPVGGGAFPTIVEREPWDGRDGELP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 AINARKMKFALLKGSFSEQGINEFLRELSFGRGSTAPVGGGAFPTIVEREPWDGRDGELP
370 380 390 400 410 420
430 440
pF1KE4 VEDDIDLSDVELDDLGKDEL
::::::::::::::::::::
NP_005 VEDDIDLSDVELDDLGKDEL
430 440
>>NP_001269636 (OMIM: 611099) protein disulfide-isomeras (437 aa)
initn: 2934 init1: 2934 opt: 2934 Z-score: 3625.6 bits: 680.0 E(85289): 3.3e-195
Smith-Waterman score: 2934; 99.5% identity (100.0% similar) in 437 aa overlap (4-440:1-437)
10 20 30 40 50 60
pF1KE4 MALLVLGLVSCTFFLAVNGLYSSSDDVIELTPSNFNREVIQSDSLWLVEFYAPWCGHCQR
..:::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MILGLVSCTFFLAVNGLYSSSDDVIELTPSNFNREVIQSDSLWLVEFYAPWCGHCQR
10 20 30 40 50
70 80 90 100 110 120
pF1KE4 LTPEWKKAATALKDVVKVGAVDADKHHSLGGQYGVQGFPTIKIFGSNKNRPEDYQGGRTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LTPEWKKAATALKDVVKVGAVDADKHHSLGGQYGVQGFPTIKIFGSNKNRPEDYQGGRTG
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE4 EAIVDAALSALRQLVKDRLGGRSGGYSSGKQGRSDSSSKKDVIELTDDSFDKNVLDSEDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EAIVDAALSALRQLVKDRLGGRSGGYSSGKQGRSDSSSKKDVIELTDDSFDKNVLDSEDV
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE4 WMVEFYAPWCGHCKNLEPEWAAAASEVKEQTKGKVKLAAVDATVNQVLASRYGIRGFPTI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WMVEFYAPWCGHCKNLEPEWAAAASEVKEQTKGKVKLAAVDATVNQVLASRYGIRGFPTI
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE4 KIFQKGESPVDYDGGRTRSDIVSRALDLFSDNAPPPELLEIINEDIAKRTCEEHQLCVVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KIFQKGESPVDYDGGRTRSDIVSRALDLFSDNAPPPELLEIINEDIAKRTCEEHQLCVVA
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE4 VLPHILDTGAAGRNSYLEVLLKLADKYKKKMWGWLWTEAGAQSELETALGIGGFGYPAMA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLPHILDTGAAGRNSYLEVLLKLADKYKKKMWGWLWTEAGAQSELETALGIGGFGYPAMA
300 310 320 330 340 350
370 380 390 400 410 420
pF1KE4 AINARKMKFALLKGSFSEQGINEFLRELSFGRGSTAPVGGGAFPTIVEREPWDGRDGELP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AINARKMKFALLKGSFSEQGINEFLRELSFGRGSTAPVGGGAFPTIVEREPWDGRDGELP
360 370 380 390 400 410
430 440
pF1KE4 VEDDIDLSDVELDDLGKDEL
::::::::::::::::::::
NP_001 VEDDIDLSDVELDDLGKDEL
420 430
>>NP_001269635 (OMIM: 611099) protein disulfide-isomeras (445 aa)
initn: 2922 init1: 2922 opt: 2922 Z-score: 3610.6 bits: 677.2 E(85289): 2.2e-194
Smith-Waterman score: 2922; 100.0% identity (100.0% similar) in 434 aa overlap (7-440:12-445)
10 20 30 40 50
pF1KE4 MALLVLGLVSCTFFLAVNGLYSSSDDVIELTPSNFNREVIQSDSLWLVEFYAPWC
:::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MYPSTTMANAPGLVSCTFFLAVNGLYSSSDDVIELTPSNFNREVIQSDSLWLVEFYAPWC
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE4 GHCQRLTPEWKKAATALKDVVKVGAVDADKHHSLGGQYGVQGFPTIKIFGSNKNRPEDYQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GHCQRLTPEWKKAATALKDVVKVGAVDADKHHSLGGQYGVQGFPTIKIFGSNKNRPEDYQ
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE4 GGRTGEAIVDAALSALRQLVKDRLGGRSGGYSSGKQGRSDSSSKKDVIELTDDSFDKNVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GGRTGEAIVDAALSALRQLVKDRLGGRSGGYSSGKQGRSDSSSKKDVIELTDDSFDKNVL
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE4 DSEDVWMVEFYAPWCGHCKNLEPEWAAAASEVKEQTKGKVKLAAVDATVNQVLASRYGIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DSEDVWMVEFYAPWCGHCKNLEPEWAAAASEVKEQTKGKVKLAAVDATVNQVLASRYGIR
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE4 GFPTIKIFQKGESPVDYDGGRTRSDIVSRALDLFSDNAPPPELLEIINEDIAKRTCEEHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GFPTIKIFQKGESPVDYDGGRTRSDIVSRALDLFSDNAPPPELLEIINEDIAKRTCEEHQ
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE4 LCVVAVLPHILDTGAAGRNSYLEVLLKLADKYKKKMWGWLWTEAGAQSELETALGIGGFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LCVVAVLPHILDTGAAGRNSYLEVLLKLADKYKKKMWGWLWTEAGAQSELETALGIGGFG
310 320 330 340 350 360
360 370 380 390 400 410
pF1KE4 YPAMAAINARKMKFALLKGSFSEQGINEFLRELSFGRGSTAPVGGGAFPTIVEREPWDGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YPAMAAINARKMKFALLKGSFSEQGINEFLRELSFGRGSTAPVGGGAFPTIVEREPWDGR
370 380 390 400 410 420
420 430 440
pF1KE4 DGELPVEDDIDLSDVELDDLGKDEL
:::::::::::::::::::::::::
NP_001 DGELPVEDDIDLSDVELDDLGKDEL
430 440
>>NP_001269634 (OMIM: 611099) protein disulfide-isomeras (488 aa)
initn: 2922 init1: 2922 opt: 2922 Z-score: 3610.0 bits: 677.3 E(85289): 2.4e-194
Smith-Waterman score: 2922; 100.0% identity (100.0% similar) in 434 aa overlap (7-440:55-488)
10 20 30
pF1KE4 MALLVLGLVSCTFFLAVNGLYSSSDDVIELTPSNFN
::::::::::::::::::::::::::::::
NP_001 SDRGSPTSPAHSLSRKSPIMYPSTTMANAPGLVSCTFFLAVNGLYSSSDDVIELTPSNFN
30 40 50 60 70 80
40 50 60 70 80 90
pF1KE4 REVIQSDSLWLVEFYAPWCGHCQRLTPEWKKAATALKDVVKVGAVDADKHHSLGGQYGVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 REVIQSDSLWLVEFYAPWCGHCQRLTPEWKKAATALKDVVKVGAVDADKHHSLGGQYGVQ
90 100 110 120 130 140
100 110 120 130 140 150
pF1KE4 GFPTIKIFGSNKNRPEDYQGGRTGEAIVDAALSALRQLVKDRLGGRSGGYSSGKQGRSDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GFPTIKIFGSNKNRPEDYQGGRTGEAIVDAALSALRQLVKDRLGGRSGGYSSGKQGRSDS
150 160 170 180 190 200
160 170 180 190 200 210
pF1KE4 SSKKDVIELTDDSFDKNVLDSEDVWMVEFYAPWCGHCKNLEPEWAAAASEVKEQTKGKVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSKKDVIELTDDSFDKNVLDSEDVWMVEFYAPWCGHCKNLEPEWAAAASEVKEQTKGKVK
210 220 230 240 250 260
220 230 240 250 260 270
pF1KE4 LAAVDATVNQVLASRYGIRGFPTIKIFQKGESPVDYDGGRTRSDIVSRALDLFSDNAPPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LAAVDATVNQVLASRYGIRGFPTIKIFQKGESPVDYDGGRTRSDIVSRALDLFSDNAPPP
270 280 290 300 310 320
280 290 300 310 320 330
pF1KE4 ELLEIINEDIAKRTCEEHQLCVVAVLPHILDTGAAGRNSYLEVLLKLADKYKKKMWGWLW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELLEIINEDIAKRTCEEHQLCVVAVLPHILDTGAAGRNSYLEVLLKLADKYKKKMWGWLW
330 340 350 360 370 380
340 350 360 370 380 390
pF1KE4 TEAGAQSELETALGIGGFGYPAMAAINARKMKFALLKGSFSEQGINEFLRELSFGRGSTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TEAGAQSELETALGIGGFGYPAMAAINARKMKFALLKGSFSEQGINEFLRELSFGRGSTA
390 400 410 420 430 440
400 410 420 430 440
pF1KE4 PVGGGAFPTIVEREPWDGRDGELPVEDDIDLSDVELDDLGKDEL
::::::::::::::::::::::::::::::::::::::::::::
NP_001 PVGGGAFPTIVEREPWDGRDGELPVEDDIDLSDVELDDLGKDEL
450 460 470 480
>>NP_001269633 (OMIM: 611099) protein disulfide-isomeras (492 aa)
initn: 2922 init1: 2922 opt: 2922 Z-score: 3609.9 bits: 677.3 E(85289): 2.5e-194
Smith-Waterman score: 2922; 100.0% identity (100.0% similar) in 434 aa overlap (7-440:59-492)
10 20 30
pF1KE4 MALLVLGLVSCTFFLAVNGLYSSSDDVIELTPSNFN
::::::::::::::::::::::::::::::
NP_001 FQPCSPTSPAHSLSRKSPIMYPSTTMANAPGLVSCTFFLAVNGLYSSSDDVIELTPSNFN
30 40 50 60 70 80
40 50 60 70 80 90
pF1KE4 REVIQSDSLWLVEFYAPWCGHCQRLTPEWKKAATALKDVVKVGAVDADKHHSLGGQYGVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 REVIQSDSLWLVEFYAPWCGHCQRLTPEWKKAATALKDVVKVGAVDADKHHSLGGQYGVQ
90 100 110 120 130 140
100 110 120 130 140 150
pF1KE4 GFPTIKIFGSNKNRPEDYQGGRTGEAIVDAALSALRQLVKDRLGGRSGGYSSGKQGRSDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GFPTIKIFGSNKNRPEDYQGGRTGEAIVDAALSALRQLVKDRLGGRSGGYSSGKQGRSDS
150 160 170 180 190 200
160 170 180 190 200 210
pF1KE4 SSKKDVIELTDDSFDKNVLDSEDVWMVEFYAPWCGHCKNLEPEWAAAASEVKEQTKGKVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSKKDVIELTDDSFDKNVLDSEDVWMVEFYAPWCGHCKNLEPEWAAAASEVKEQTKGKVK
210 220 230 240 250 260
220 230 240 250 260 270
pF1KE4 LAAVDATVNQVLASRYGIRGFPTIKIFQKGESPVDYDGGRTRSDIVSRALDLFSDNAPPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LAAVDATVNQVLASRYGIRGFPTIKIFQKGESPVDYDGGRTRSDIVSRALDLFSDNAPPP
270 280 290 300 310 320
280 290 300 310 320 330
pF1KE4 ELLEIINEDIAKRTCEEHQLCVVAVLPHILDTGAAGRNSYLEVLLKLADKYKKKMWGWLW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELLEIINEDIAKRTCEEHQLCVVAVLPHILDTGAAGRNSYLEVLLKLADKYKKKMWGWLW
330 340 350 360 370 380
340 350 360 370 380 390
pF1KE4 TEAGAQSELETALGIGGFGYPAMAAINARKMKFALLKGSFSEQGINEFLRELSFGRGSTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TEAGAQSELETALGIGGFGYPAMAAINARKMKFALLKGSFSEQGINEFLRELSFGRGSTA
390 400 410 420 430 440
400 410 420 430 440
pF1KE4 PVGGGAFPTIVEREPWDGRDGELPVEDDIDLSDVELDDLGKDEL
::::::::::::::::::::::::::::::::::::::::::::
NP_001 PVGGGAFPTIVEREPWDGRDGELPVEDDIDLSDVELDDLGKDEL
450 460 470 480 490
>>XP_011508610 (OMIM: 611099) PREDICTED: protein disulfi (402 aa)
initn: 2576 init1: 2576 opt: 2576 Z-score: 3183.6 bits: 598.1 E(85289): 1.4e-170
Smith-Waterman score: 2576; 100.0% identity (100.0% similar) in 385 aa overlap (1-385:1-385)
10 20 30 40 50 60
pF1KE4 MALLVLGLVSCTFFLAVNGLYSSSDDVIELTPSNFNREVIQSDSLWLVEFYAPWCGHCQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MALLVLGLVSCTFFLAVNGLYSSSDDVIELTPSNFNREVIQSDSLWLVEFYAPWCGHCQR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 LTPEWKKAATALKDVVKVGAVDADKHHSLGGQYGVQGFPTIKIFGSNKNRPEDYQGGRTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LTPEWKKAATALKDVVKVGAVDADKHHSLGGQYGVQGFPTIKIFGSNKNRPEDYQGGRTG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 EAIVDAALSALRQLVKDRLGGRSGGYSSGKQGRSDSSSKKDVIELTDDSFDKNVLDSEDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EAIVDAALSALRQLVKDRLGGRSGGYSSGKQGRSDSSSKKDVIELTDDSFDKNVLDSEDV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 WMVEFYAPWCGHCKNLEPEWAAAASEVKEQTKGKVKLAAVDATVNQVLASRYGIRGFPTI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WMVEFYAPWCGHCKNLEPEWAAAASEVKEQTKGKVKLAAVDATVNQVLASRYGIRGFPTI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 KIFQKGESPVDYDGGRTRSDIVSRALDLFSDNAPPPELLEIINEDIAKRTCEEHQLCVVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KIFQKGESPVDYDGGRTRSDIVSRALDLFSDNAPPPELLEIINEDIAKRTCEEHQLCVVA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 VLPHILDTGAAGRNSYLEVLLKLADKYKKKMWGWLWTEAGAQSELETALGIGGFGYPAMA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VLPHILDTGAAGRNSYLEVLLKLADKYKKKMWGWLWTEAGAQSELETALGIGGFGYPAMA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 AINARKMKFALLKGSFSEQGINEFLRELSFGRGSTAPVGGGAFPTIVEREPWDGRDGELP
:::::::::::::::::::::::::
XP_011 AINARKMKFALLKGSFSEQGINEFLSFPWRMTLTSVMWSLMT
370 380 390 400
>>NP_005304 (OMIM: 602046) protein disulfide-isomerase A (505 aa)
initn: 423 init1: 249 opt: 310 Z-score: 380.9 bits: 79.8 E(85289): 1.8e-14
Smith-Waterman score: 355; 36.8% identity (64.9% similar) in 174 aa overlap (157-328:22-183)
130 140 150 160 170 180
pF1KE4 ALSALRQLVKDRLGGRSGGYSSGKQGRSDSSSKKDVIELTDDSFDKNVLD--SEDVWMVE
.. .::.:::::.:.. . : : . .::
NP_005 MRLRRLALFPGVALLLAAARLAAASDVLELTDDNFESRISDTGSAGLMLVE
10 20 30 40 50
190 200 210 220 230 240
pF1KE4 FYAPWCGHCKNLEPEWAAAASEVKEQTKGKVKLAAVDATVNQVLASRYGIRGFPTIKIFQ
:.:::::::: : ::. :::...: : : :: :: :.: ..::. :.::.:::.
NP_005 FFAPWCGHCKRLAPEYEAAATRLK----GIVPLAKVDCTANTNTCNKYGVSGYPTLKIFR
60 70 80 90 100
250 260 270 280 290 300
pF1KE4 KGESPVDYDGGRTRSDIVSRALDLFSDNAPPPELLEIINEDIAKRTCEEHQLCVVAVLPH
:: ::: :: . :::. .. .: : . . .:. :. ... .:. .
NP_005 DGEEAGAYDGPRTADGIVSH----LKKQAGPASV-PLRTEEEFKKFISDKDASIVGFFD-
110 120 130 140 150 160
310 320 330 340 350 360
pF1KE4 ILDTGAAGRNSYLEVLLKLADKYKKKMWGWLWTEAGAQSELETALGIGGFGYPAMAAINA
:. . ... .:.. .: :.:.
NP_005 --DSFSEAHSEFLKAASNLRDNYRFAHTNVESLVNEYDDNGEGIILFRPSHLTNKFEDKT
170 180 190 200 210
>--
initn: 228 init1: 148 opt: 269 Z-score: 330.2 bits: 70.4 E(85289): 1.2e-11
Smith-Waterman score: 269; 34.4% identity (62.6% similar) in 163 aa overlap (130-289:348-497)
100 110 120 130 140 150
pF1KE4 TIKIFGSNKNRPEDYQGGRTGEAIVDAALSALRQLVKDRLGGRSGGY-SSGKQGRSDSSS
::.....: . : : .: .:...
NP_005 STAGEIPVVAIRTAKGEKFVMQEEFSRDGKALERFLQDYFDGNLKRYLKSEPIPESNDGP
320 330 340 350 360 370
160 170 180 190 200 210
pF1KE4 KKDVIELTDDSFDKNVLDSEDVWMVEFYAPWCGHCKNLEPEWAAAASEVKEQTKGKVKLA
: :. ..::. : . . ..:::::::::::::::.. . ..... . . .:
NP_005 VKVVVA---ENFDEIVNNENKDVLIEFYAPWCGHCKNLEPKYKELGEKLSKDPN--IVIA
380 390 400 410 420 430
220 230 240 250 260 270
pF1KE4 AVDATVNQVLASRYGIRGFPTIKIF--QKGESPVDYDGGRTRSDIVSRALDLFSDNAPPP
.:::.:.: : : .:::::: . .: .: :.::: ::..: : . . ::
NP_005 KMDATANDV-PSPYEVRGFPTIYFSPANKKLNPKKYEGGRELSDFISY---LQREATNPP
440 450 460 470 480
280 290 300 310 320 330
pF1KE4 ELLEIINEDIAKRTCEEHQLCVVAVLPHILDTGAAGRNSYLEVLLKLADKYKKKMWGWLW
.:.:. :.
NP_005 ----VIQEEKPKKKKKAQEDL
490 500
>>XP_011524337 (OMIM: 616102) PREDICTED: protein disulfi (229 aa)
initn: 382 init1: 159 opt: 282 Z-score: 351.8 bits: 73.3 E(85289): 7.4e-13
Smith-Waterman score: 329; 45.3% identity (73.6% similar) in 106 aa overlap (160-265:25-126)
130 140 150 160 170 180
pF1KE4 ALRQLVKDRLGGRSGGYSSGKQGRSDSSSKKDVIELTDDSFDKNVLDSEDVWMVEFYAPW
: .: :.:: .: ..:.:.:.:::::
XP_011 MAAWKSWTALRLCATVVVLDMVVCKGFVEDLDESFKEN--RNDDIWLVDFYAPW
10 20 30 40 50
190 200 210 220 230 240
pF1KE4 CGHCKNLEPEWAAAASEVKEQTKGKVKLAAVDATVNQVLASRYGIRGFPTIKIFQKGESP
:::::.::: : .. :.: . . ::.. .::: . .::..:.::.::::.. ::.
XP_011 CGHCKKLEPIWNEVGLEMK-SIGSPVKVGKMDATSYSSIASEFGVRGYPTIKLL-KGDLA
60 70 80 90 100 110
250 260 270 280 290 300
pF1KE4 VDYDGGRTRSDIVSRALDLFSDNAPPPELLEIINEDIAKRTCEEHQLCVVAVLPHILDTG
.: : ::..::. :
XP_011 YNYRGPRTKDDIIEFAHRVSGALIRPLPSQQMFEHMQKRHRVFFVYVGGESPLKEKYIDA
120 130 140 150 160 170
>>XP_011524336 (OMIM: 616102) PREDICTED: protein disulfi (231 aa)
initn: 382 init1: 159 opt: 282 Z-score: 351.8 bits: 73.3 E(85289): 7.5e-13
Smith-Waterman score: 329; 45.3% identity (73.6% similar) in 106 aa overlap (160-265:25-126)
130 140 150 160 170 180
pF1KE4 ALRQLVKDRLGGRSGGYSSGKQGRSDSSSKKDVIELTDDSFDKNVLDSEDVWMVEFYAPW
: .: :.:: .: ..:.:.:.:::::
XP_011 MAAWKSWTALRLCATVVVLDMVVCKGFVEDLDESFKEN--RNDDIWLVDFYAPW
10 20 30 40 50
190 200 210 220 230 240
pF1KE4 CGHCKNLEPEWAAAASEVKEQTKGKVKLAAVDATVNQVLASRYGIRGFPTIKIFQKGESP
:::::.::: : .. :.: . . ::.. .::: . .::..:.::.::::.. ::.
XP_011 CGHCKKLEPIWNEVGLEMK-SIGSPVKVGKMDATSYSSIASEFGVRGYPTIKLL-KGDLA
60 70 80 90 100 110
250 260 270 280 290 300
pF1KE4 VDYDGGRTRSDIVSRALDLFSDNAPPPELLEIINEDIAKRTCEEHQLCVVAVLPHILDTG
.: : ::..::. :
XP_011 YNYRGPRTKDDIIEFAHRVSGALIRPLPSQQMFEHMQKRHRVFFVYVGGESPLKEKYIDA
120 130 140 150 160 170
>>NP_061895 (OMIM: 616102) protein disulfide-isomerase T (454 aa)
initn: 405 init1: 159 opt: 282 Z-score: 347.0 bits: 73.4 E(85289): 1.4e-12
Smith-Waterman score: 329; 45.3% identity (73.6% similar) in 106 aa overlap (160-265:25-126)
130 140 150 160 170 180
pF1KE4 ALRQLVKDRLGGRSGGYSSGKQGRSDSSSKKDVIELTDDSFDKNVLDSEDVWMVEFYAPW
: .: :.:: .: ..:.:.:.:::::
NP_061 MAAWKSWTALRLCATVVVLDMVVCKGFVEDLDESFKEN--RNDDIWLVDFYAPW
10 20 30 40 50
190 200 210 220 230 240
pF1KE4 CGHCKNLEPEWAAAASEVKEQTKGKVKLAAVDATVNQVLASRYGIRGFPTIKIFQKGESP
:::::.::: : .. :.: . . ::.. .::: . .::..:.::.::::.. ::.
NP_061 CGHCKKLEPIWNEVGLEMK-SIGSPVKVGKMDATSYSSIASEFGVRGYPTIKLL-KGDLA
60 70 80 90 100 110
250 260 270 280 290 300
pF1KE4 VDYDGGRTRSDIVSRALDLFSDNAPPPELLEIINEDIAKRTCEEHQLCVVAVLPHILDTG
.: : ::..::. :
NP_061 YNYRGPRTKDDIIEFAHRVSGALIRPLPSQQMFEHMQKRHRVFFVYVGGESPLKEKYIDA
120 130 140 150 160 170
440 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 00:41:37 2016 done: Sun Nov 6 00:41:38 2016
Total Scan time: 9.550 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]