Result of FASTA (omim) for
pFN21AE4423
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE4423, 438 aa
1>>>pF1KE4423 438 - 438 aa - 438 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.5576+/-0.000409; mu= 16.0788+/- 0.025
mean_var=73.3430+/-16.040, 0's: 0 Z-trim(111.7): 135 B-trim: 271 in 1/54
Lambda= 0.149760
statistics sampled from 20251 (20408) to 20251 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.603), E-opt: 0.2 (0.239), width: 16
Scan time: 6.520
The best scores are: opt bits E(85289)
NP_973729 (OMIM: 145505) acyl-coenzyme A synthetas ( 438) 3006 659.1 6.2e-189
XP_016879013 (OMIM: 145505) PREDICTED: acyl-coenzy ( 538) 2797 614.0 2.9e-175
NP_005613 (OMIM: 145505) acyl-coenzyme A synthetas ( 586) 2797 614.1 3.1e-175
XP_016879012 (OMIM: 145505) PREDICTED: acyl-coenzy ( 596) 2797 614.1 3.2e-175
NP_001073923 (OMIM: 614360) acyl-coenzyme A synthe ( 580) 1639 363.9 6.4e-100
NP_001311300 (OMIM: 614361) acyl-coenzyme A synthe ( 579) 1629 361.7 2.8e-99
NP_060358 (OMIM: 614361) acyl-coenzyme A synthetas ( 579) 1629 361.7 2.8e-99
NP_001311301 (OMIM: 614361) acyl-coenzyme A synthe ( 582) 1629 361.7 2.9e-99
XP_006721119 (OMIM: 614361) PREDICTED: acyl-coenzy ( 582) 1629 361.7 2.9e-99
XP_011544213 (OMIM: 145505) PREDICTED: acyl-coenzy ( 623) 1437 320.2 9.3e-87
XP_016878413 (OMIM: 614358) PREDICTED: acyl-coenzy ( 447) 1355 302.4 1.5e-81
XP_016878412 (OMIM: 614358) PREDICTED: acyl-coenzy ( 577) 1355 302.5 1.9e-81
NP_001295101 (OMIM: 614358) acyl-coenzyme A synthe ( 577) 1355 302.5 1.9e-81
NP_001295883 (OMIM: 614358) acyl-coenzyme A synthe ( 577) 1355 302.5 1.9e-81
XP_011544031 (OMIM: 614357) PREDICTED: acyl-coenzy ( 454) 1351 301.6 2.8e-81
NP_443188 (OMIM: 614357) acyl-coenzyme A synthetas ( 577) 1351 301.6 3.4e-81
NP_001305819 (OMIM: 614357) acyl-coenzyme A synthe ( 577) 1351 301.6 3.4e-81
XP_006721079 (OMIM: 614357) PREDICTED: acyl-coenzy ( 543) 1346 300.5 6.9e-81
XP_005255361 (OMIM: 614359) PREDICTED: acyl-coenzy ( 431) 1337 298.5 2.2e-80
NP_001098539 (OMIM: 614359) acyl-coenzyme A synthe ( 577) 1337 298.6 2.8e-80
NP_872423 (OMIM: 614359) acyl-coenzyme A synthetas ( 577) 1337 298.6 2.8e-80
XP_006721080 (OMIM: 614357) PREDICTED: acyl-coenzy ( 516) 1230 275.5 2.3e-73
XP_016878414 (OMIM: 614358) PREDICTED: acyl-coenzy ( 429) 1168 262.0 2.1e-69
NP_001295098 (OMIM: 614358) acyl-coenzyme A synthe ( 498) 1168 262.1 2.4e-69
XP_011544126 (OMIM: 614359) PREDICTED: acyl-coenzy ( 498) 1150 258.2 3.6e-68
XP_011544032 (OMIM: 614357) PREDICTED: acyl-coenzy ( 419) 1077 242.4 1.7e-63
XP_016878403 (OMIM: 614357) PREDICTED: acyl-coenzy ( 355) 1073 241.4 2.8e-63
XP_016878694 (OMIM: 614359) PREDICTED: acyl-coenzy ( 339) 990 223.5 6.6e-58
NP_001311302 (OMIM: 614361) acyl-coenzyme A synthe ( 208) 767 175.2 1.4e-43
XP_011544033 (OMIM: 614357) PREDICTED: acyl-coenzy ( 378) 666 153.5 8.6e-37
XP_006721081 (OMIM: 614357) PREDICTED: acyl-coenzy ( 357) 616 142.7 1.5e-33
XP_011544034 (OMIM: 614357) PREDICTED: acyl-coenzy ( 357) 616 142.7 1.5e-33
XP_016878415 (OMIM: 614358) PREDICTED: acyl-coenzy ( 348) 595 138.2 3.3e-32
XP_016878404 (OMIM: 614357) PREDICTED: acyl-coenzy ( 339) 523 122.6 1.6e-27
NP_001229322 (OMIM: 605832) acetyl-coenzyme A synt ( 606) 260 65.9 3.2e-10
XP_006723889 (OMIM: 605832) PREDICTED: acetyl-coen ( 629) 260 65.9 3.3e-10
XP_011527214 (OMIM: 605832) PREDICTED: acetyl-coen ( 642) 260 65.9 3.4e-10
XP_011527213 (OMIM: 605832) PREDICTED: acetyl-coen ( 674) 260 65.9 3.5e-10
XP_011527211 (OMIM: 605832) PREDICTED: acetyl-coen ( 687) 260 66.0 3.6e-10
NP_061147 (OMIM: 605832) acetyl-coenzyme A synthet ( 701) 260 66.0 3.7e-10
XP_005260513 (OMIM: 605832) PREDICTED: acetyl-coen ( 711) 260 66.0 3.7e-10
NP_001070020 (OMIM: 605832) acetyl-coenzyme A synt ( 714) 260 66.0 3.7e-10
XP_011527210 (OMIM: 605832) PREDICTED: acetyl-coen ( 714) 260 66.0 3.7e-10
XP_005260512 (OMIM: 605832) PREDICTED: acetyl-coen ( 724) 260 66.0 3.8e-10
XP_011527209 (OMIM: 605832) PREDICTED: acetyl-coen ( 724) 260 66.0 3.8e-10
XP_011527208 (OMIM: 605832) PREDICTED: acetyl-coen ( 727) 260 66.0 3.8e-10
XP_011527207 (OMIM: 605832) PREDICTED: acetyl-coen ( 737) 260 66.0 3.8e-10
NP_001239605 (OMIM: 614355) acetyl-coenzyme A synt ( 568) 241 61.8 5.3e-09
NP_001239606 (OMIM: 614355) acetyl-coenzyme A synt ( 575) 241 61.8 5.3e-09
NP_115890 (OMIM: 614355) acetyl-coenzyme A synthet ( 689) 241 61.8 6.2e-09
>>NP_973729 (OMIM: 145505) acyl-coenzyme A synthetase AC (438 aa)
initn: 3006 init1: 3006 opt: 3006 Z-score: 3512.9 bits: 659.1 E(85289): 6.2e-189
Smith-Waterman score: 3006; 100.0% identity (100.0% similar) in 438 aa overlap (1-438:1-438)
10 20 30 40 50 60
pF1KE4 MLARVTRKMLRHAKCFQRLAIFGSVRALHKDNRTATPQNFSNYESMKQDFKLGIPEYFNF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_973 MLARVTRKMLRHAKCFQRLAIFGSVRALHKDNRTATPQNFSNYESMKQDFKLGIPEYFNF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 AKDVLDQWTDKEKAGKKPSNPAFWWINRNGEEMRWSFEELGSLSRKFANILSEACSLQRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_973 AKDVLDQWTDKEKAGKKPSNPAFWWINRNGEEMRWSFEELGSLSRKFANILSEACSLQRG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 DRVILILPRVPEWWLANVACLRTGTVLIPGTTQLTQKDILYRLQSSKANCIITNDVLAPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_973 DRVILILPRVPEWWLANVACLRTGTVLIPGTTQLTQKDILYRLQSSKANCIITNDVLAPA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 VDAVASKCENLHSKLIVSENSREGWGNLKELMKHASDSHTCVKTKHNEIMAIFFTSGTSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_973 VDAVASKCENLHSKLIVSENSREGWGNLKELMKHASDSHTCVKTKHNEIMAIFFTSGTSG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 YPKMTAHTHSSFGLGLSVNGRFWLDLTPSDVMWNTSDTGWAKSAWSSVFSPWIQGACVFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_973 YPKMTAHTHSSFGLGLSVNGRFWLDLTPSDVMWNTSDTGWAKSAWSSVFSPWIQGACVFT
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 HHLPRFEPTSILQTLSKYPITVFCSAPTVYRMLVQNDITSYKFKSLKHCVSAGEPITPDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_973 HHLPRFEPTSILQTLSKYPITVFCSAPTVYRMLVQNDITSYKFKSLKHCVSAGEPITPDV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 TEKWRNKTGLDIYEGYGQTETVLICGNFKGMKIKPGSMGKPSPAFDVKVCTSPSRRMFNN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_973 TEKWRNKTGLDIYEGYGQTETVLICGNFKGMKIKPGSMGKPSPAFDVKVCTSPSRRMFNN
370 380 390 400 410 420
430
pF1KE4 PICTLPTYRLPPYKLSLL
::::::::::::::::::
NP_973 PICTLPTYRLPPYKLSLL
430
>>XP_016879013 (OMIM: 145505) PREDICTED: acyl-coenzyme A (538 aa)
initn: 2797 init1: 2797 opt: 2797 Z-score: 3267.5 bits: 614.0 E(85289): 2.9e-175
Smith-Waterman score: 2797; 99.8% identity (100.0% similar) in 409 aa overlap (1-409:1-409)
10 20 30 40 50 60
pF1KE4 MLARVTRKMLRHAKCFQRLAIFGSVRALHKDNRTATPQNFSNYESMKQDFKLGIPEYFNF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MLARVTRKMLRHAKCFQRLAIFGSVRALHKDNRTATPQNFSNYESMKQDFKLGIPEYFNF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 AKDVLDQWTDKEKAGKKPSNPAFWWINRNGEEMRWSFEELGSLSRKFANILSEACSLQRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AKDVLDQWTDKEKAGKKPSNPAFWWINRNGEEMRWSFEELGSLSRKFANILSEACSLQRG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 DRVILILPRVPEWWLANVACLRTGTVLIPGTTQLTQKDILYRLQSSKANCIITNDVLAPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DRVILILPRVPEWWLANVACLRTGTVLIPGTTQLTQKDILYRLQSSKANCIITNDVLAPA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 VDAVASKCENLHSKLIVSENSREGWGNLKELMKHASDSHTCVKTKHNEIMAIFFTSGTSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VDAVASKCENLHSKLIVSENSREGWGNLKELMKHASDSHTCVKTKHNEIMAIFFTSGTSG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 YPKMTAHTHSSFGLGLSVNGRFWLDLTPSDVMWNTSDTGWAKSAWSSVFSPWIQGACVFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YPKMTAHTHSSFGLGLSVNGRFWLDLTPSDVMWNTSDTGWAKSAWSSVFSPWIQGACVFT
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 HHLPRFEPTSILQTLSKYPITVFCSAPTVYRMLVQNDITSYKFKSLKHCVSAGEPITPDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HHLPRFEPTSILQTLSKYPITVFCSAPTVYRMLVQNDITSYKFKSLKHCVSAGEPITPDV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 TEKWRNKTGLDIYEGYGQTETVLICGNFKGMKIKPGSMGKPSPAFDVKVCTSPSRRMFNN
::::::::::::::::::::::::::::::::::::::::::::::::.
XP_016 TEKWRNKTGLDIYEGYGQTETVLICGNFKGMKIKPGSMGKPSPAFDVKIVDVNGNVLPPG
370 380 390 400 410 420
430
pF1KE4 PICTLPTYRLPPYKLSLL
XP_016 QEGDIGIQVLPNRPFGLFTHYVDNPSKTASTLRGNFYITGDRGYMDKDGYFWFVARADDV
430 440 450 460 470 480
>>NP_005613 (OMIM: 145505) acyl-coenzyme A synthetase AC (586 aa)
initn: 2797 init1: 2797 opt: 2797 Z-score: 3267.0 bits: 614.1 E(85289): 3.1e-175
Smith-Waterman score: 2797; 99.8% identity (100.0% similar) in 409 aa overlap (1-409:1-409)
10 20 30 40 50 60
pF1KE4 MLARVTRKMLRHAKCFQRLAIFGSVRALHKDNRTATPQNFSNYESMKQDFKLGIPEYFNF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MLARVTRKMLRHAKCFQRLAIFGSVRALHKDNRTATPQNFSNYESMKQDFKLGIPEYFNF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 AKDVLDQWTDKEKAGKKPSNPAFWWINRNGEEMRWSFEELGSLSRKFANILSEACSLQRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 AKDVLDQWTDKEKAGKKPSNPAFWWINRNGEEMRWSFEELGSLSRKFANILSEACSLQRG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 DRVILILPRVPEWWLANVACLRTGTVLIPGTTQLTQKDILYRLQSSKANCIITNDVLAPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 DRVILILPRVPEWWLANVACLRTGTVLIPGTTQLTQKDILYRLQSSKANCIITNDVLAPA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 VDAVASKCENLHSKLIVSENSREGWGNLKELMKHASDSHTCVKTKHNEIMAIFFTSGTSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 VDAVASKCENLHSKLIVSENSREGWGNLKELMKHASDSHTCVKTKHNEIMAIFFTSGTSG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 YPKMTAHTHSSFGLGLSVNGRFWLDLTPSDVMWNTSDTGWAKSAWSSVFSPWIQGACVFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 YPKMTAHTHSSFGLGLSVNGRFWLDLTPSDVMWNTSDTGWAKSAWSSVFSPWIQGACVFT
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 HHLPRFEPTSILQTLSKYPITVFCSAPTVYRMLVQNDITSYKFKSLKHCVSAGEPITPDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 HHLPRFEPTSILQTLSKYPITVFCSAPTVYRMLVQNDITSYKFKSLKHCVSAGEPITPDV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 TEKWRNKTGLDIYEGYGQTETVLICGNFKGMKIKPGSMGKPSPAFDVKVCTSPSRRMFNN
::::::::::::::::::::::::::::::::::::::::::::::::.
NP_005 TEKWRNKTGLDIYEGYGQTETVLICGNFKGMKIKPGSMGKPSPAFDVKIVDVNGNVLPPG
370 380 390 400 410 420
430
pF1KE4 PICTLPTYRLPPYKLSLL
NP_005 QEGDIGIQVLPNRPFGLFTHYVDNPSKTASTLRGNFYITGDRGYMDKDGYFWFVARADDV
430 440 450 460 470 480
>>XP_016879012 (OMIM: 145505) PREDICTED: acyl-coenzyme A (596 aa)
initn: 2797 init1: 2797 opt: 2797 Z-score: 3266.9 bits: 614.1 E(85289): 3.2e-175
Smith-Waterman score: 2797; 99.8% identity (100.0% similar) in 409 aa overlap (1-409:1-409)
10 20 30 40 50 60
pF1KE4 MLARVTRKMLRHAKCFQRLAIFGSVRALHKDNRTATPQNFSNYESMKQDFKLGIPEYFNF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MLARVTRKMLRHAKCFQRLAIFGSVRALHKDNRTATPQNFSNYESMKQDFKLGIPEYFNF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 AKDVLDQWTDKEKAGKKPSNPAFWWINRNGEEMRWSFEELGSLSRKFANILSEACSLQRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AKDVLDQWTDKEKAGKKPSNPAFWWINRNGEEMRWSFEELGSLSRKFANILSEACSLQRG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 DRVILILPRVPEWWLANVACLRTGTVLIPGTTQLTQKDILYRLQSSKANCIITNDVLAPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DRVILILPRVPEWWLANVACLRTGTVLIPGTTQLTQKDILYRLQSSKANCIITNDVLAPA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 VDAVASKCENLHSKLIVSENSREGWGNLKELMKHASDSHTCVKTKHNEIMAIFFTSGTSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VDAVASKCENLHSKLIVSENSREGWGNLKELMKHASDSHTCVKTKHNEIMAIFFTSGTSG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 YPKMTAHTHSSFGLGLSVNGRFWLDLTPSDVMWNTSDTGWAKSAWSSVFSPWIQGACVFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YPKMTAHTHSSFGLGLSVNGRFWLDLTPSDVMWNTSDTGWAKSAWSSVFSPWIQGACVFT
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 HHLPRFEPTSILQTLSKYPITVFCSAPTVYRMLVQNDITSYKFKSLKHCVSAGEPITPDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HHLPRFEPTSILQTLSKYPITVFCSAPTVYRMLVQNDITSYKFKSLKHCVSAGEPITPDV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 TEKWRNKTGLDIYEGYGQTETVLICGNFKGMKIKPGSMGKPSPAFDVKVCTSPSRRMFNN
::::::::::::::::::::::::::::::::::::::::::::::::.
XP_016 TEKWRNKTGLDIYEGYGQTETVLICGNFKGMKIKPGSMGKPSPAFDVKIVDVNGNVLPPG
370 380 390 400 410 420
430
pF1KE4 PICTLPTYRLPPYKLSLL
XP_016 QEGDIGIQVLPNRPFGLFTHYVDNPSKTASTLRGNFYITGDRGYMDKDGYFWFVARADDV
430 440 450 460 470 480
>>NP_001073923 (OMIM: 614360) acyl-coenzyme A synthetase (580 aa)
initn: 1628 init1: 1584 opt: 1639 Z-score: 1914.9 bits: 363.9 E(85289): 6.4e-100
Smith-Waterman score: 1639; 56.0% identity (86.7% similar) in 384 aa overlap (26-409:21-403)
10 20 30 40 50 60
pF1KE4 MLARVTRKMLRHAKCFQRLAIFGSVRALHKDNRTATPQNFSNYESMKQDFKLGIPEYFNF
: ::::.. :: .....:.... . .:. :::
NP_001 MKIFFRYQTFRFIWLTKPPGRRLHKDHQLWTPLTLADFEAINR-CNRPLPKNFNF
10 20 30 40 50
70 80 90 100 110 120
pF1KE4 AKDVLDQWTDKEKAGKKPSNPAFWWINRNGEEMRWSFEELGSLSRKFANILSEACSLQRG
: ::::::..:::.:..:.:::.::.: .:.:..:::.:::::::: ::.:.. :.::::
NP_001 AADVLDQWSQKEKTGERPANPALWWVNGKGDEVKWSFRELGSLSRKAANVLTKPCGLQRG
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE4 DRVILILPRVPEWWLANVACLRTGTVLIPGTTQLTQKDILYRLQSSKANCIITNDVLAPA
::. .::::.:::::.::::.::: ...::: ::: :::::::..:::.::.... .:::
NP_001 DRLAVILPRIPEWWLVNVACIRTGIIFMPGTIQLTAKDILYRLRASKAKCIVASEEVAPA
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE4 VDAVASKCENLHSKLIVSENSREGWGNLKELMKHASDSHTCVKTKHNEIMAIFFTSGTSG
:.... .: .:..::.:: .: .:: ...::.. ::. :.::.: .: :.:.:::::.:
NP_001 VESIVLECPDLKTKLLVSPQSWNGWLSFQELFQFASEEHSCVETGSQEPMTIYFTSGTTG
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE4 YPKMTAHTHSSFGLGLSVNGRFWLDLTPSDVMWNTSDTGWAKSAWSSVFSPWIQGACVFT
.:::. :..::.:.:... ::.:::: ::..:: :::::.:.: .:::: :. :::::.
NP_001 FPKMAQHSQSSLGIGFTLCGRYWLDLKSSDIIWNMSDTGWVKAAIGSVFSSWLCGACVFV
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE4 HHLPRFEPTSILQTLSKYPITVFCSAPTVYRMLVQNDITSYKFKSLKHCVSAGEPITPDV
:.. .:. ..:.::. ::::..:: :::::::::.:. ::::::.::...:::..:.:
NP_001 HRMAQFDTDTFLDTLTTYPITTLCSPPTVYRMLVQKDLKRYKFKSLRHCLTGGEPLNPEV
300 310 320 330 340 350
370 380 390 400 410 420
pF1KE4 TEKWRNKTGLDIYEGYGQTETVLICGNFKGMKIKPGSMGKPSPAFDVKVCTSPSRRMFNN
:.:: .:::..::::::::. .::.: ::..:::::::: .::..
NP_001 LEQWRVQTGLELYEGYGQTEVGMICANQKGQEIKPGSMGKGMLPYDVQIIDENGNVLPPG
360 370 380 390 400 410
430
pF1KE4 PICTLPTYRLPPYKLSLL
NP_001 KEGEIALRLKPTRPFCFFSKYVDNPQKTAATIRGDFYVTGDRGVMDSDGYFWFVGRADDV
420 430 440 450 460 470
>>NP_001311300 (OMIM: 614361) acyl-coenzyme A synthetase (579 aa)
initn: 1618 init1: 1074 opt: 1629 Z-score: 1903.2 bits: 361.7 E(85289): 2.8e-99
Smith-Waterman score: 1629; 55.1% identity (83.5% similar) in 405 aa overlap (7-409:2-403)
10 20 30 40 50
pF1KE4 MLARVTRKMLRHAKCFQRLAIFGSVRALH-KDNRTATPQNF-SNYESMKQDFKLGIPEYF
: ::: .: : . . : : .::.. ...:... .: .::::
NP_001 MRPWLRHL-VLQALRNSRAFCGSHGKPAPLPVPQKIVATWEAISLGRQL-VPEYF
10 20 30 40 50
60 70 80 90 100 110
pF1KE4 NFAKDVLDQWTDKEKAGKKPSNPAFWWINRNGEEMRWSFEELGSLSRKFANILSEACSLQ
:::.:::: :. :.::..: ::::::.: .: :..:::::::. ::: ::.:. ::.::
NP_001 NFAHDVLDVWSRLEEAGHRPPNPAFWWVNGTGAEIKWSFEELGKQSRKAANVLGGACGLQ
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE4 RGDRVILILPRVPEWWLANVACLRTGTVLIPGTTQLTQKDILYRLQSSKANCIITNDVLA
:::..:.:::.:::::..:::.:::::.:::.::::.::. ::::.:.:. :::.: ::
NP_001 PGDRMMLVLPRLPEWWLVSVACMRTGTVMIPGVTQLTEKDLKYRLQASRAKSIITSDSLA
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE4 PAVDAVASKCENLHSKLIVSENSREGWGNLKELMKHASDSHTCVKTKHNEIMAIFFTSGT
: :::....: .:..::.::..:: :: :..::...:: :.:..:: . .::.:::::
NP_001 PRVDAISAECPSLQTKLLVSDSSRPGWLNFRELLREASTEHNCMRTKSRDPLAIYFTSGT
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE4 SGYPKMTAHTHSSFGLGLSVNGRFWLDLTPSDVMWNTSDTGWAKSAWSSVFSPWIQGACV
.: :::. :..::.:::. ..:: :. :: ::..:::.::::.:.::. .:: : .:.:.
NP_001 TGAPKMVEHSQSSYGLGFVASGRRWVALTESDIFWNTTDTGWVKAAWT-LFSAWPNGSCI
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE4 FTHHLPRFEPTSILQTLSKYPITVFCSAPTVYRMLVQNDITSYKFKSLKHCVSAGEPITP
:.:.::: . ::.::::.:::..: .::..:.:::.:.: :.:.::.::...:: ..:
NP_001 FVHELPRVDAKVILNTLSKFPITTLCCVPTIFRLLVQEDLTRYQFQSLRHCLTGGEALNP
300 310 320 330 340 350
360 370 380 390 400 410
pF1KE4 DVTEKWRNKTGLDIYEGYGQTETVLICGNFKGMKIKPGSMGKPSPAFDVKVCTSPSRRMF
:: :::...::...::::::.:::.::.: :::::: ::::: :: .::..
NP_001 DVREKWKHQTGVELYEGYGQSETVVICANPKGMKIKSGSMGKASPPYDVQIVDDEGNVLP
360 370 380 390 400 410
420 430
pF1KE4 NNPICTLPTYRLPPYKLSLL
NP_001 PGEEGNVAVRIRPTRPFCFFNCYLDNPEKTAASEQGDFYITGDRARMDKDGYFWFMGRND
420 430 440 450 460 470
>>NP_060358 (OMIM: 614361) acyl-coenzyme A synthetase AC (579 aa)
initn: 1618 init1: 1074 opt: 1629 Z-score: 1903.2 bits: 361.7 E(85289): 2.8e-99
Smith-Waterman score: 1629; 55.1% identity (83.5% similar) in 405 aa overlap (7-409:2-403)
10 20 30 40 50
pF1KE4 MLARVTRKMLRHAKCFQRLAIFGSVRALH-KDNRTATPQNF-SNYESMKQDFKLGIPEYF
: ::: .: : . . : : .::.. ...:... .: .::::
NP_060 MRPWLRHL-VLQALRNSRAFCGSHGKPAPLPVPQKIVATWEAISLGRQL-VPEYF
10 20 30 40 50
60 70 80 90 100 110
pF1KE4 NFAKDVLDQWTDKEKAGKKPSNPAFWWINRNGEEMRWSFEELGSLSRKFANILSEACSLQ
:::.:::: :. :.::..: ::::::.: .: :..:::::::. ::: ::.:. ::.::
NP_060 NFAHDVLDVWSRLEEAGHRPPNPAFWWVNGTGAEIKWSFEELGKQSRKAANVLGGACGLQ
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE4 RGDRVILILPRVPEWWLANVACLRTGTVLIPGTTQLTQKDILYRLQSSKANCIITNDVLA
:::..:.:::.:::::..:::.:::::.:::.::::.::. ::::.:.:. :::.: ::
NP_060 PGDRMMLVLPRLPEWWLVSVACMRTGTVMIPGVTQLTEKDLKYRLQASRAKSIITSDSLA
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE4 PAVDAVASKCENLHSKLIVSENSREGWGNLKELMKHASDSHTCVKTKHNEIMAIFFTSGT
: :::....: .:..::.::..:: :: :..::...:: :.:..:: . .::.:::::
NP_060 PRVDAISAECPSLQTKLLVSDSSRPGWLNFRELLREASTEHNCMRTKSRDPLAIYFTSGT
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE4 SGYPKMTAHTHSSFGLGLSVNGRFWLDLTPSDVMWNTSDTGWAKSAWSSVFSPWIQGACV
.: :::. :..::.:::. ..:: :. :: ::..:::.::::.:.::. .:: : .:.:.
NP_060 TGAPKMVEHSQSSYGLGFVASGRRWVALTESDIFWNTTDTGWVKAAWT-LFSAWPNGSCI
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE4 FTHHLPRFEPTSILQTLSKYPITVFCSAPTVYRMLVQNDITSYKFKSLKHCVSAGEPITP
:.:.::: . ::.::::.:::..: .::..:.:::.:.: :.:.::.::...:: ..:
NP_060 FVHELPRVDAKVILNTLSKFPITTLCCVPTIFRLLVQEDLTRYQFQSLRHCLTGGEALNP
300 310 320 330 340 350
360 370 380 390 400 410
pF1KE4 DVTEKWRNKTGLDIYEGYGQTETVLICGNFKGMKIKPGSMGKPSPAFDVKVCTSPSRRMF
:: :::...::...::::::.:::.::.: :::::: ::::: :: .::..
NP_060 DVREKWKHQTGVELYEGYGQSETVVICANPKGMKIKSGSMGKASPPYDVQIVDDEGNVLP
360 370 380 390 400 410
420 430
pF1KE4 NNPICTLPTYRLPPYKLSLL
NP_060 PGEEGNVAVRIRPTRPFCFFNCYLDNPEKTAASEQGDFYITGDRARMDKDGYFWFMGRND
420 430 440 450 460 470
>>NP_001311301 (OMIM: 614361) acyl-coenzyme A synthetase (582 aa)
initn: 1618 init1: 1074 opt: 1629 Z-score: 1903.2 bits: 361.7 E(85289): 2.9e-99
Smith-Waterman score: 1629; 55.1% identity (83.5% similar) in 405 aa overlap (7-409:2-403)
10 20 30 40 50
pF1KE4 MLARVTRKMLRHAKCFQRLAIFGSVRALH-KDNRTATPQNF-SNYESMKQDFKLGIPEYF
: ::: .: : . . : : .::.. ...:... .: .::::
NP_001 MRPWLRHL-VLQALRNSRAFCGSHGKPAPLPVPQKIVATWEAISLGRQL-VPEYF
10 20 30 40 50
60 70 80 90 100 110
pF1KE4 NFAKDVLDQWTDKEKAGKKPSNPAFWWINRNGEEMRWSFEELGSLSRKFANILSEACSLQ
:::.:::: :. :.::..: ::::::.: .: :..:::::::. ::: ::.:. ::.::
NP_001 NFAHDVLDVWSRLEEAGHRPPNPAFWWVNGTGAEIKWSFEELGKQSRKAANVLGGACGLQ
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE4 RGDRVILILPRVPEWWLANVACLRTGTVLIPGTTQLTQKDILYRLQSSKANCIITNDVLA
:::..:.:::.:::::..:::.:::::.:::.::::.::. ::::.:.:. :::.: ::
NP_001 PGDRMMLVLPRLPEWWLVSVACMRTGTVMIPGVTQLTEKDLKYRLQASRAKSIITSDSLA
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE4 PAVDAVASKCENLHSKLIVSENSREGWGNLKELMKHASDSHTCVKTKHNEIMAIFFTSGT
: :::....: .:..::.::..:: :: :..::...:: :.:..:: . .::.:::::
NP_001 PRVDAISAECPSLQTKLLVSDSSRPGWLNFRELLREASTEHNCMRTKSRDPLAIYFTSGT
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE4 SGYPKMTAHTHSSFGLGLSVNGRFWLDLTPSDVMWNTSDTGWAKSAWSSVFSPWIQGACV
.: :::. :..::.:::. ..:: :. :: ::..:::.::::.:.::. .:: : .:.:.
NP_001 TGAPKMVEHSQSSYGLGFVASGRRWVALTESDIFWNTTDTGWVKAAWT-LFSAWPNGSCI
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE4 FTHHLPRFEPTSILQTLSKYPITVFCSAPTVYRMLVQNDITSYKFKSLKHCVSAGEPITP
:.:.::: . ::.::::.:::..: .::..:.:::.:.: :.:.::.::...:: ..:
NP_001 FVHELPRVDAKVILNTLSKFPITTLCCVPTIFRLLVQEDLTRYQFQSLRHCLTGGEALNP
300 310 320 330 340 350
360 370 380 390 400 410
pF1KE4 DVTEKWRNKTGLDIYEGYGQTETVLICGNFKGMKIKPGSMGKPSPAFDVKVCTSPSRRMF
:: :::...::...::::::.:::.::.: :::::: ::::: :: .::..
NP_001 DVREKWKHQTGVELYEGYGQSETVVICANPKGMKIKSGSMGKASPPYDVQIVDDEGNVLP
360 370 380 390 400 410
420 430
pF1KE4 NNPICTLPTYRLPPYKLSLL
NP_001 PGEEGNVAVRIRPTRPFCFFNCYLDNPEKTAASEQGDFYITGDRARMDKDGYFWFMGRND
420 430 440 450 460 470
>>XP_006721119 (OMIM: 614361) PREDICTED: acyl-coenzyme A (582 aa)
initn: 1618 init1: 1074 opt: 1629 Z-score: 1903.2 bits: 361.7 E(85289): 2.9e-99
Smith-Waterman score: 1629; 55.1% identity (83.5% similar) in 405 aa overlap (7-409:2-403)
10 20 30 40 50
pF1KE4 MLARVTRKMLRHAKCFQRLAIFGSVRALH-KDNRTATPQNF-SNYESMKQDFKLGIPEYF
: ::: .: : . . : : .::.. ...:... .: .::::
XP_006 MRPWLRHL-VLQALRNSRAFCGSHGKPAPLPVPQKIVATWEAISLGRQL-VPEYF
10 20 30 40 50
60 70 80 90 100 110
pF1KE4 NFAKDVLDQWTDKEKAGKKPSNPAFWWINRNGEEMRWSFEELGSLSRKFANILSEACSLQ
:::.:::: :. :.::..: ::::::.: .: :..:::::::. ::: ::.:. ::.::
XP_006 NFAHDVLDVWSRLEEAGHRPPNPAFWWVNGTGAEIKWSFEELGKQSRKAANVLGGACGLQ
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE4 RGDRVILILPRVPEWWLANVACLRTGTVLIPGTTQLTQKDILYRLQSSKANCIITNDVLA
:::..:.:::.:::::..:::.:::::.:::.::::.::. ::::.:.:. :::.: ::
XP_006 PGDRMMLVLPRLPEWWLVSVACMRTGTVMIPGVTQLTEKDLKYRLQASRAKSIITSDSLA
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE4 PAVDAVASKCENLHSKLIVSENSREGWGNLKELMKHASDSHTCVKTKHNEIMAIFFTSGT
: :::....: .:..::.::..:: :: :..::...:: :.:..:: . .::.:::::
XP_006 PRVDAISAECPSLQTKLLVSDSSRPGWLNFRELLREASTEHNCMRTKSRDPLAIYFTSGT
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE4 SGYPKMTAHTHSSFGLGLSVNGRFWLDLTPSDVMWNTSDTGWAKSAWSSVFSPWIQGACV
.: :::. :..::.:::. ..:: :. :: ::..:::.::::.:.::. .:: : .:.:.
XP_006 TGAPKMVEHSQSSYGLGFVASGRRWVALTESDIFWNTTDTGWVKAAWT-LFSAWPNGSCI
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE4 FTHHLPRFEPTSILQTLSKYPITVFCSAPTVYRMLVQNDITSYKFKSLKHCVSAGEPITP
:.:.::: . ::.::::.:::..: .::..:.:::.:.: :.:.::.::...:: ..:
XP_006 FVHELPRVDAKVILNTLSKFPITTLCCVPTIFRLLVQEDLTRYQFQSLRHCLTGGEALNP
300 310 320 330 340 350
360 370 380 390 400 410
pF1KE4 DVTEKWRNKTGLDIYEGYGQTETVLICGNFKGMKIKPGSMGKPSPAFDVKVCTSPSRRMF
:: :::...::...::::::.:::.::.: :::::: ::::: :: .::..
XP_006 DVREKWKHQTGVELYEGYGQSETVVICANPKGMKIKSGSMGKASPPYDVQIVDDEGNVLP
360 370 380 390 400 410
420 430
pF1KE4 NNPICTLPTYRLPPYKLSLL
XP_006 PGEEGNVAVRIRPTRPFCFFNCYLDNPEKTAASEQGDFYITGDRARMDKDGYFWFMGRND
420 430 440 450 460 470
>>XP_011544213 (OMIM: 145505) PREDICTED: acyl-coenzyme A (623 aa)
initn: 1437 init1: 1437 opt: 1437 Z-score: 1678.6 bits: 320.2 E(85289): 9.3e-87
Smith-Waterman score: 2713; 91.5% identity (91.7% similar) in 446 aa overlap (1-409:1-446)
10 20 30 40 50 60
pF1KE4 MLARVTRKMLRHAKCFQRLAIFGSVRALHKDNRTATPQNFSNYESMKQDFKLGIPEYFNF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MLARVTRKMLRHAKCFQRLAIFGSVRALHKDNRTATPQNFSNYESMKQDFKLGIPEYFNF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 AKDVLDQWTDKEKAGKKPSNPAFWWINRNGEEMRWSFEELGSLSRKFANILSEACSLQRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AKDVLDQWTDKEKAGKKPSNPAFWWINRNGEEMRWSFEELGSLSRKFANILSEACSLQRG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 DRVILILPRVPEWWLANVACLRTGTVLIPGTTQLTQKDILYRLQSSKANCIITNDVLAPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DRVILILPRVPEWWLANVACLRTGTVLIPGTTQLTQKDILYRLQSSKANCIITNDVLAPA
130 140 150 160 170 180
190 200 210
pF1KE4 VDAVASKCENLHSKLIVSENSREGWGNLKELMK---------------------------
:::::::::::::::::::::::::::::::::
XP_011 VDAVASKCENLHSKLIVSENSREGWGNLKELMKVFLCHPGWSTVARSWLTATSTSLVQAI
190 200 210 220 230 240
220 230 240 250 260
pF1KE4 ----------HASDSHTCVKTKHNEIMAIFFTSGTSGYPKMTAHTHSSFGLGLSVNGRFW
::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSLLSSWDYRHASDSHTCVKTKHNEIMAIFFTSGTSGYPKMTAHTHSSFGLGLSVNGRFW
250 260 270 280 290 300
270 280 290 300 310 320
pF1KE4 LDLTPSDVMWNTSDTGWAKSAWSSVFSPWIQGACVFTHHLPRFEPTSILQTLSKYPITVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LDLTPSDVMWNTSDTGWAKSAWSSVFSPWIQGACVFTHHLPRFEPTSILQTLSKYPITVF
310 320 330 340 350 360
330 340 350 360 370 380
pF1KE4 CSAPTVYRMLVQNDITSYKFKSLKHCVSAGEPITPDVTEKWRNKTGLDIYEGYGQTETVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CSAPTVYRMLVQNDITSYKFKSLKHCVSAGEPITPDVTEKWRNKTGLDIYEGYGQTETVL
370 380 390 400 410 420
390 400 410 420 430
pF1KE4 ICGNFKGMKIKPGSMGKPSPAFDVKVCTSPSRRMFNNPICTLPTYRLPPYKLSLL
:::::::::::::::::::::::::.
XP_011 ICGNFKGMKIKPGSMGKPSPAFDVKIVDVNGNVLPPGQEGDIGIQVLPNRPFGLFTHYVD
430 440 450 460 470 480
438 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 22:37:14 2016 done: Sat Nov 5 22:37:15 2016
Total Scan time: 6.520 Total Display time: 0.050
Function used was FASTA [36.3.4 Apr, 2011]