Result of FASTA (ccds) for
pFN21AE4422
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE4422, 437 aa
1>>>pF1KE4422 437 - 437 aa - 437 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.7046+/-0.000818; mu= 15.3542+/- 0.049
mean_var=68.9591+/-13.768, 0's: 0 Z-trim(107.6): 15 B-trim: 0 in 0/49
Lambda= 0.154447
statistics sampled from 9676 (9683) to 9676 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.671), E-opt: 0.2 (0.297), width: 16
Scan time: 2.640
The best scores are: opt bits E(32554)
CCDS5637.1 SGCE gene_id:8910|Hs108|chr7 ( 437) 2980 673.0 1.6e-193
CCDS47643.1 SGCE gene_id:8910|Hs108|chr7 ( 462) 2838 641.3 5.7e-184
CCDS75634.1 SGCE gene_id:8910|Hs108|chr7 ( 396) 2430 550.4 1.2e-156
CCDS47642.1 SGCE gene_id:8910|Hs108|chr7 ( 451) 2360 534.8 6.4e-152
CCDS32679.1 SGCA gene_id:6442|Hs108|chr17 ( 387) 1082 250.0 2.9e-66
CCDS45729.1 SGCA gene_id:6442|Hs108|chr17 ( 263) 505 121.4 1.1e-27
>>CCDS5637.1 SGCE gene_id:8910|Hs108|chr7 (437 aa)
initn: 2980 init1: 2980 opt: 2980 Z-score: 3587.8 bits: 673.0 E(32554): 1.6e-193
Smith-Waterman score: 2980; 99.5% identity (99.8% similar) in 437 aa overlap (1-437:1-437)
10 20 30 40 50 60
pF1KE4 MQLPRWWELGDPCAWTGQGRGTRRMSPATTGTFLLTVYSIFSKVHSDRSVYPSAGVLFVH
::::::::::::::::::::::::::::::::::::::::::::::::.:::::::::::
CCDS56 MQLPRWWELGDPCAWTGQGRGTRRMSPATTGTFLLTVYSIFSKVHSDRNVYPSAGVLFVH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 VLEREYFKGEFPPYPKPGEISNDPITFNTNLMGYPDRPGWLRYIQRTPYSDGVLYGSPTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 VLEREYFKGEFPPYPKPGEISNDPITFNTNLMGYPDRPGWLRYIQRTPYSDGVLYGSPTA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 ENVGKPTIIEITAYNRRTFETARHNLIINIMSAEDFPLPYQAEFFIKNMNVEEMLASEVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 ENVGKPTIIEITAYNRRTFETARHNLIINIMSAEDFPLPYQAEFFIKNMNVEEMLASEVL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 GDFLGAVKNVWQPERLNAINITSALDRGGRVPLPINDLKEGVYVMVGADVPFSSCLREVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 GDFLGAVKNVWQPERLNAINITSALDRGGRVPLPINDLKEGVYVMVGADVPFSSCLREVE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 NPQNQLRCSQEMEPVITCDKKFRTQFYIDWCKISLVDKTKQVSTYQEVIRGEGILPDGGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 NPQNQLRCSQEMEPVITCDKKFRTQFYIDWCKISLVDKTKQVSTYQEVIRGEGILPDGGE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 YKPPSDSLKSRDYYTDFLITLAVPSAVALVLFLILAYIMCCRREGVEKRNMQTPDIQLVH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 YKPPSDSLKSRDYYTDFLITLAVPSAVALVLFLILAYIMCCRREGVEKRNMQTPDIQLVH
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 HSAIQKSTKELRDMSKNREIAWPLSTLPVFHPVTGEIIHPLHTDNYDSTNMPLMQTQQNL
:::::::::::::::::::::::::::::::::::::: :::::::::::::::::::::
CCDS56 HSAIQKSTKELRDMSKNREIAWPLSTLPVFHPVTGEIIPPLHTDNYDSTNMPLMQTQQNL
370 380 390 400 410 420
430
pF1KE4 PHQTQIPQQQTTGKWYP
:::::::::::::::::
CCDS56 PHQTQIPQQQTTGKWYP
430
>>CCDS47643.1 SGCE gene_id:8910|Hs108|chr7 (462 aa)
initn: 2836 init1: 2836 opt: 2838 Z-score: 3416.4 bits: 641.3 E(32554): 5.7e-184
Smith-Waterman score: 2920; 94.2% identity (94.4% similar) in 462 aa overlap (1-437:1-462)
10 20 30 40 50 60
pF1KE4 MQLPRWWELGDPCAWTGQGRGTRRMSPATTGTFLLTVYSIFSKVHSDRSVYPSAGVLFVH
::::::::::::::::::::::::::::::::::::::::::::::::.:::::::::::
CCDS47 MQLPRWWELGDPCAWTGQGRGTRRMSPATTGTFLLTVYSIFSKVHSDRNVYPSAGVLFVH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 VLEREYFKGEFPPYPKPGEISNDPITFNTNLMGYPDRPGWLRYIQRTPYSDGVLYGSPTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 VLEREYFKGEFPPYPKPGEISNDPITFNTNLMGYPDRPGWLRYIQRTPYSDGVLYGSPTA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 ENVGKPTIIEITAYNRRTFETARHNLIINIMSAEDFPLPYQAEFFIKNMNVEEMLASEVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 ENVGKPTIIEITAYNRRTFETARHNLIINIMSAEDFPLPYQAEFFIKNMNVEEMLASEVL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 GDFLGAVKNVWQPERLNAINITSALDRGGRVPLPINDLKEGVYVMVGADVPFSSCLREVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 GDFLGAVKNVWQPERLNAINITSALDRGGRVPLPINDLKEGVYVMVGADVPFSSCLREVE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 NPQNQLRCSQEMEPVITCDKKFRTQFYIDWCKISLVDKTKQVSTYQEVIRGEGILPDGGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 NPQNQLRCSQEMEPVITCDKKFRTQFYIDWCKISLVDKTKQVSTYQEVIRGEGILPDGGE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 YKPPSDSLKSRDYYTDFLITLAVPSAVALVLFLILAYIMCCRREGVEKRNMQTPDIQLVH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 YKPPSDSLKSRDYYTDFLITLAVPSAVALVLFLILAYIMCCRREGVEKRNMQTPDIQLVH
310 320 330 340 350 360
370 380 390 400 410
pF1KE4 HSAIQKSTKELRDMSKNREIAWPLSTLPVFHPVTGEIIHPLHTDNYDSTNMPLMQTQQ--
:::::::::::::::::::::::::::::::::::::: :::::::::::::::::::
CCDS47 HSAIQKSTKELRDMSKNREIAWPLSTLPVFHPVTGEIIPPLHTDNYDSTNMPLMQTQQWS
370 380 390 400 410 420
420 430
pF1KE4 -----------------------NLPHQTQIPQQQTTGKWYP
:::::::::::::::::::
CCDS47 FAPVAQAGVQWSDLGSLQPPPPRNLPHQTQIPQQQTTGKWYP
430 440 450 460
>>CCDS75634.1 SGCE gene_id:8910|Hs108|chr7 (396 aa)
initn: 2687 init1: 2430 opt: 2430 Z-score: 2926.1 bits: 550.4 E(32554): 1.2e-156
Smith-Waterman score: 2609; 90.4% identity (90.4% similar) in 437 aa overlap (1-437:1-396)
10 20 30 40 50 60
pF1KE4 MQLPRWWELGDPCAWTGQGRGTRRMSPATTGTFLLTVYSIFSKVHSDRSVYPSAGVLFVH
::::::::::::::::::::::::::::::::::::
CCDS75 MQLPRWWELGDPCAWTGQGRGTRRMSPATTGTFLLT------------------------
10 20 30
70 80 90 100 110 120
pF1KE4 VLEREYFKGEFPPYPKPGEISNDPITFNTNLMGYPDRPGWLRYIQRTPYSDGVLYGSPTA
:::::::::::::::::::::::::::::::::::::::::::
CCDS75 -----------------GEISNDPITFNTNLMGYPDRPGWLRYIQRTPYSDGVLYGSPTA
40 50 60 70
130 140 150 160 170 180
pF1KE4 ENVGKPTIIEITAYNRRTFETARHNLIINIMSAEDFPLPYQAEFFIKNMNVEEMLASEVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS75 ENVGKPTIIEITAYNRRTFETARHNLIINIMSAEDFPLPYQAEFFIKNMNVEEMLASEVL
80 90 100 110 120 130
190 200 210 220 230 240
pF1KE4 GDFLGAVKNVWQPERLNAINITSALDRGGRVPLPINDLKEGVYVMVGADVPFSSCLREVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS75 GDFLGAVKNVWQPERLNAINITSALDRGGRVPLPINDLKEGVYVMVGADVPFSSCLREVE
140 150 160 170 180 190
250 260 270 280 290 300
pF1KE4 NPQNQLRCSQEMEPVITCDKKFRTQFYIDWCKISLVDKTKQVSTYQEVIRGEGILPDGGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS75 NPQNQLRCSQEMEPVITCDKKFRTQFYIDWCKISLVDKTKQVSTYQEVIRGEGILPDGGE
200 210 220 230 240 250
310 320 330 340 350 360
pF1KE4 YKPPSDSLKSRDYYTDFLITLAVPSAVALVLFLILAYIMCCRREGVEKRNMQTPDIQLVH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS75 YKPPSDSLKSRDYYTDFLITLAVPSAVALVLFLILAYIMCCRREGVEKRNMQTPDIQLVH
260 270 280 290 300 310
370 380 390 400 410 420
pF1KE4 HSAIQKSTKELRDMSKNREIAWPLSTLPVFHPVTGEIIHPLHTDNYDSTNMPLMQTQQNL
:::::::::::::::::::::::::::::::::::::: :::::::::::::::::::::
CCDS75 HSAIQKSTKELRDMSKNREIAWPLSTLPVFHPVTGEIIPPLHTDNYDSTNMPLMQTQQNL
320 330 340 350 360 370
430
pF1KE4 PHQTQIPQQQTTGKWYP
:::::::::::::::::
CCDS75 PHQTQIPQQQTTGKWYP
380 390
>>CCDS47642.1 SGCE gene_id:8910|Hs108|chr7 (451 aa)
initn: 2864 init1: 2360 opt: 2360 Z-score: 2840.9 bits: 534.8 E(32554): 6.4e-152
Smith-Waterman score: 2850; 97.5% identity (97.7% similar) in 433 aa overlap (1-433:1-424)
10 20 30 40 50 60
pF1KE4 MQLPRWWELGDPCAWTGQGRGTRRMSPATTGTFLLTVYSIFSKVHSDRSVYPSAGVLFVH
::::::::::::::::::::::::::::::::::::::::::::::::.:::::::::::
CCDS47 MQLPRWWELGDPCAWTGQGRGTRRMSPATTGTFLLTVYSIFSKVHSDRNVYPSAGVLFVH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 VLEREYFKGEFPPYPKPGEISNDPITFNTNLMGYPDRPGWLRYIQRTPYSDGVLYGSPTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 VLEREYFKGEFPPYPKPGEISNDPITFNTNLMGYPDRPGWLRYIQRTPYSDGVLYGSPTA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 ENVGKPTIIEITAYNRRTFETARHNLIINIMSAEDFPLPYQAEFFIKNMNVEEMLASEVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 ENVGKPTIIEITAYNRRTFETARHNLIINIMSAEDFPLPYQAEFFIKNMNVEEMLASEVL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 GDFLGAVKNVWQPERLNAINITSALDRGGRVPLPINDLKEGVYVMVGADVPFSSCLREVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 GDFLGAVKNVWQPERLNAINITSALDRGGRVPLPINDLKEGVYVMVGADVPFSSCLREVE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 NPQNQLRCSQEMEPVITCDKKFRTQFYIDWCKISLVDKTKQVSTYQEVIRGEGILPDGGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 NPQNQLRCSQEMEPVITCDKKFRTQFYIDWCKISLVDKTKQVSTYQEVIRGEGILPDGGE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 YKPPSDSLKSRDYYTDFLITLAVPSAVALVLFLILAYIMCCRREGVEKRNMQTPDIQLVH
:::::::::::::::::::::::::::::::::::::::::::::: :::::
CCDS47 YKPPSDSLKSRDYYTDFLITLAVPSAVALVLFLILAYIMCCRREGV---------IQLVH
310 320 330 340 350
370 380 390 400 410 420
pF1KE4 HSAIQKSTKELRDMSKNREIAWPLSTLPVFHPVTGEIIHPLHTDNYDSTNMPLMQTQQNL
:::::::::::::::::::::::::::::::::::::: :::::::::::::::::::::
CCDS47 HSAIQKSTKELRDMSKNREIAWPLSTLPVFHPVTGEIIPPLHTDNYDSTNMPLMQTQQNL
360 370 380 390 400 410
430
pF1KE4 PHQTQIPQQQTTGKWYP
:::::::::::::
CCDS47 PHQTQIPQQQTTGDFRLTTFQRFEVNGIPEERKLTEAMNL
420 430 440 450
>>CCDS32679.1 SGCA gene_id:6442|Hs108|chr17 (387 aa)
initn: 1055 init1: 554 opt: 1082 Z-score: 1303.0 bits: 250.0 E(32554): 2.9e-66
Smith-Waterman score: 1082; 44.6% identity (71.6% similar) in 370 aa overlap (49-418:27-387)
20 30 40 50 60 70
pF1KE4 GRGTRRMSPATTGTFLLTVYSIFSKVHSDRSVYPSAGVLFVHVLEREYFKGEFPPYPKPG
...: .: .:::.:..: : . :
CCDS32 MAETLFWTPLLVVLLAGLGDTEAQQTTLHPLVGRVFVHTLDHETFLSLPEHVAVPP
10 20 30 40 50
80 90 100 110 120 130
pF1KE4 EISNDPITFNTNLMGYPDRPGWLRYIQRTPYSDGVLYGSPTAENVGKPTIIEITAYNRRT
. ::....:.:.:: : :::: ::.:. : :::: : :. : .::.::::: .
CCDS32 AVH---ITYHAHLQGHPDLPRWLRYTQRSPHHPGFLYGSATPEDRGLQ-VIEVTAYNRDS
60 70 80 90 100 110
140 150 160 170 180 190
pF1KE4 FETARHNLIINIMSAEDFPLPYQAEFFIKNMNVEEMLASEVLGDFLGAVKNVWQPERLNA
:.:.:. :...: . : :::::::.... ..::.: : . ::.:. ..:.: .:.
CCDS32 FDTTRQRLVLEIGDPEGPLLPYQAEFLVRSHDAEEVLPSTPASRFLSALGGLWEPGELQL
120 130 140 150 160 170
200 210 220 230 240 250
pF1KE4 INITSALDRGGRVPLPINDLKEGVYVMVGADVPFSSCLREVENPQNQLRCSQEMEPVITC
.:.::::::::::::::. :::::. ::. :::.::. : .:... ::.: . :...:
CCDS32 LNVTSALDRGGRVPLPIEGRKEGVYIKVGSASPFSTCLKMVASPDSHARCAQGQPPLLSC
180 190 200 210 220 230
260 270 280 290 300 310
pF1KE4 DKKFRTQFYIDWCKISLVDKTKQVSTYQEVIRGEGILPDGGEYKPPSDSLKSRDYYTDFL
. .: .:::...::::. . . :.::: . ::... .::. .: :
CCDS32 YDTLAPHFRVDWCNVTLVDKSVPEPADEVPTPGDGILEHDPFFCPPTEA-PDRDFLVDAL
240 250 260 270 280 290
320 330 340 350 360 370
pF1KE4 ITLAVPSAVALVLFLILAYIMCCRREGVEKRNMQTPDIQLVHHSAIQKSTKELRDMSKNR
.:: :: :::.: :.:::.::::::: ::.. : :::.::: .:. .:.:::.:. .:
CCDS32 VTLLVPLLVALLLTLLLAYVMCCRREGRLKRDLATSDIQMVHHCTIHGNTEELRQMAASR
300 310 320 330 340 350
380 390 400 410 420 430
pF1KE4 EIAWPLSTLPVFHPVTGEIIHPLHTDNYDSTNMPLMQTQQNLPHQTQIPQQQTTGKWYP
:. ::::::.:. ::: . : ::...::. :.
CCDS32 EVPRPLSTLPMFNVHTGERLPP----RVDSAQVPLILDQH
360 370 380
>>CCDS45729.1 SGCA gene_id:6442|Hs108|chr17 (263 aa)
initn: 495 init1: 323 opt: 505 Z-score: 610.8 bits: 121.4 E(32554): 1.1e-27
Smith-Waterman score: 505; 45.4% identity (73.0% similar) in 174 aa overlap (49-222:27-196)
20 30 40 50 60 70
pF1KE4 GRGTRRMSPATTGTFLLTVYSIFSKVHSDRSVYPSAGVLFVHVLEREYFKGEFPPYPKPG
...: .: .:::.:..: : . :
CCDS45 MAETLFWTPLLVVLLAGLGDTEAQQTTLHPLVGRVFVHTLDHETFLSLPEHVAVPP
10 20 30 40 50
80 90 100 110 120 130
pF1KE4 EISNDPITFNTNLMGYPDRPGWLRYIQRTPYSDGVLYGSPTAENVGKPTIIEITAYNRRT
. ::....:.:.:: : :::: ::.:. : :::: : :. : .::.::::: .
CCDS45 AVH---ITYHAHLQGHPDLPRWLRYTQRSPHHPGFLYGSATPEDRGLQ-VIEVTAYNRDS
60 70 80 90 100 110
140 150 160 170 180 190
pF1KE4 FETARHNLIINIMSAEDFPLPYQAEFFIKNMNVEEMLASEVLGDFLGAVKNVWQPERLNA
:.:.:. :...: . : :::::::.... ..::.: : . ::.:. ..:.: .:.
CCDS45 FDTTRQRLVLEIGDPEGPLLPYQAEFLVRSHDAEEVLPSTPASRFLSALGGLWEPGELQL
120 130 140 150 160 170
200 210 220 230 240 250
pF1KE4 INITSALDRGGRVPLPINDLKEGVYVMVGADVPFSSCLREVENPQNQLRCSQEMEPVITC
.:.::::::::::::::. :::.
CCDS45 LNVTSALDRGGRVPLPIEGRKEGLKRDLATSDIQMVHHCTIHGNTEELRQMAASREVPRP
180 190 200 210 220 230
437 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 01:13:07 2016 done: Sun Nov 6 01:13:08 2016
Total Scan time: 2.640 Total Display time: 0.050
Function used was FASTA [36.3.4 Apr, 2011]