FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE4409, 423 aa
  1>>>pF1KE4409 423 - 423 aa - 423 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.0325+/-0.000329; mu= 19.0636+/- 0.020
 mean_var=63.2169+/-13.124, 0's: 0 Z-trim(115.6): 33  B-trim: 1297 in 1/51
 Lambda= 0.161309
 statistics sampled from 26059 (26085) to 26059 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.678), E-opt: 0.2 (0.306), width:  16
 Scan time:  7.960

The best scores are:                                      opt bits E(85289)
NP_003071 (OMIM: 603498) sphingomyelin phosphodies ( 423) 2917 687.3 1.9e-197
XP_011534381 (OMIM: 603498) PREDICTED: sphingomyel ( 318) 2181 516.0 5.5e-146
XP_005267166 (OMIM: 603498) PREDICTED: sphingomyel ( 243) 1670 397.0 2.8e-110


>>NP_003071 (OMIM: 603498) sphingomyelin phosphodiestera  (423 aa)
 initn: 2917 init1: 2917 opt: 2917  Z-score: 3665.7  bits: 687.3 E(85289): 1.9e-197
Smith-Waterman score: 2917; 99.8% identity (99.8% similar) in 423 aa overlap (1-423:1-423)

               10        20        30        40        50        60
pF1KE4 MKPNFSLRLRIFNLNCWGIPYLSKHRADRMRRLGDFLNQESFDLALLEEVWSEQDFQYLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MKPNFSLRLRIFNLNCWGIPYLSKHRADRMRRLGDFLNQESFDLALLEEVWSEQDFQYLR
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE4 QKLSPTYPAAHHFRSGIIGSGLCVFSKHPIQELTQHIYTLNGYPYMIHHGDWFSGKAVGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 QKLSPTYPAAHHFRSGIIGSGLCVFSKHPIQELTQHIYTLNGYPYMIHHGDWFSGKAVGL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE4 LVLHLSGMVLNAYVTHLHAEYNRQKDIYLAHRVAQAWELAQFIHHTSKKADVVLLCGDLN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LVLHLSGMVLNAYVTHLHAEYNRQKDIYLAHRVAQAWELAQFIHHTSKKADVVLLCGDLN
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE4 MHPEDLGCCLLKEWTGLHDAYLETRDFKGSEEGNTMVPKNCYVSQQELKPFPFGVRIDYV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MHPEDLGCCLLKEWTGLHDAYLETRDFKGSEEGNTMVPKNCYVSQQELKPFPFGVRIDYV
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE4 LYKAVSGFYISCKSFETTTGFDPHSGTPLSDHEALMATLFVRHSPPQQNPSSTHGPAERS
       :::::::::::::::::::::::: :::::::::::::::::::::::::::::::::::
NP_003 LYKAVSGFYISCKSFETTTGFDPHRGTPLSDHEALMATLFVRHSPPQQNPSSTHGPAERS
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE4 PLMCVLKEAWTELGLGMAQARWWATFASYVIGLGLLLLALLCVLAAGGGAGEAAILLWTP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 PLMCVLKEAWTELGLGMAQARWWATFASYVIGLGLLLLALLCVLAAGGGAGEAAILLWTP
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KE4 SVGLVLWAGAFYLFHVQEVNGLYRAQAELQHVLGRAREAQDLGPEPQPALLLGQQEGDRT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 SVGLVLWAGAFYLFHVQEVNGLYRAQAELQHVLGRAREAQDLGPEPQPALLLGQQEGDRT
              370       380       390       400       410       420

          
pF1KE4 KEQ
       :::
NP_003 KEQ
          

>>XP_011534381 (OMIM: 603498) PREDICTED: sphingomyelin p  (318 aa)
 initn: 2181 init1: 2181 opt: 2181  Z-score: 2741.9  bits: 516.0 E(85289): 5.5e-146
Smith-Waterman score: 2181; 99.7% identity (99.7% similar) in 318 aa overlap (106-423:1-318)

          80        90       100       110       120       130     
pF1KE4 GIIGSGLCVFSKHPIQELTQHIYTLNGYPYMIHHGDWFSGKAVGLLVLHLSGMVLNAYVT
                                     ::::::::::::::::::::::::::::::
XP_011                               MIHHGDWFSGKAVGLLVLHLSGMVLNAYVT
                                             10        20        30

         140       150       160       170       180       190     
pF1KE4 HLHAEYNRQKDIYLAHRVAQAWELAQFIHHTSKKADVVLLCGDLNMHPEDLGCCLLKEWT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HLHAEYNRQKDIYLAHRVAQAWELAQFIHHTSKKADVVLLCGDLNMHPEDLGCCLLKEWT
               40        50        60        70        80        90

         200       210       220       230       240       250     
pF1KE4 GLHDAYLETRDFKGSEEGNTMVPKNCYVSQQELKPFPFGVRIDYVLYKAVSGFYISCKSF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLHDAYLETRDFKGSEEGNTMVPKNCYVSQQELKPFPFGVRIDYVLYKAVSGFYISCKSF
              100       110       120       130       140       150

         260       270       280       290       300       310     
pF1KE4 ETTTGFDPHSGTPLSDHEALMATLFVRHSPPQQNPSSTHGPAERSPLMCVLKEAWTELGL
       ::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ETTTGFDPHRGTPLSDHEALMATLFVRHSPPQQNPSSTHGPAERSPLMCVLKEAWTELGL
              160       170       180       190       200       210

         320       330       340       350       360       370     
pF1KE4 GMAQARWWATFASYVIGLGLLLLALLCVLAAGGGAGEAAILLWTPSVGLVLWAGAFYLFH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GMAQARWWATFASYVIGLGLLLLALLCVLAAGGGAGEAAILLWTPSVGLVLWAGAFYLFH
              220       230       240       250       260       270

         380       390       400       410       420   
pF1KE4 VQEVNGLYRAQAELQHVLGRAREAQDLGPEPQPALLLGQQEGDRTKEQ
       ::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VQEVNGLYRAQAELQHVLGRAREAQDLGPEPQPALLLGQQEGDRTKEQ
              280       290       300       310        

>>XP_005267166 (OMIM: 603498) PREDICTED: sphingomyelin p  (243 aa)
 initn: 1670 init1: 1670 opt: 1670  Z-score: 2100.9  bits: 397.0 E(85289): 2.8e-110
Smith-Waterman score: 1670; 99.6% identity (99.6% similar) in 243 aa overlap (181-423:1-243)

              160       170       180       190       200       210
pF1KE4 HRVAQAWELAQFIHHTSKKADVVLLCGDLNMHPEDLGCCLLKEWTGLHDAYLETRDFKGS
                                     ::::::::::::::::::::::::::::::
XP_005                               MHPEDLGCCLLKEWTGLHDAYLETRDFKGS
                                             10        20        30

              220       230       240       250       260       270
pF1KE4 EEGNTMVPKNCYVSQQELKPFPFGVRIDYVLYKAVSGFYISCKSFETTTGFDPHSGTPLS
       :::::::::::::::::::::::::::::::::::::::::::::::::::::: :::::
XP_005 EEGNTMVPKNCYVSQQELKPFPFGVRIDYVLYKAVSGFYISCKSFETTTGFDPHRGTPLS
               40        50        60        70        80        90

              280       290       300       310       320       330
pF1KE4 DHEALMATLFVRHSPPQQNPSSTHGPAERSPLMCVLKEAWTELGLGMAQARWWATFASYV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DHEALMATLFVRHSPPQQNPSSTHGPAERSPLMCVLKEAWTELGLGMAQARWWATFASYV
              100       110       120       130       140       150

              340       350       360       370       380       390
pF1KE4 IGLGLLLLALLCVLAAGGGAGEAAILLWTPSVGLVLWAGAFYLFHVQEVNGLYRAQAELQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IGLGLLLLALLCVLAAGGGAGEAAILLWTPSVGLVLWAGAFYLFHVQEVNGLYRAQAELQ
              160       170       180       190       200       210

              400       410       420   
pF1KE4 HVLGRAREAQDLGPEPQPALLLGQQEGDRTKEQ
       :::::::::::::::::::::::::::::::::
XP_005 HVLGRAREAQDLGPEPQPALLLGQQEGDRTKEQ
              220       230       240   




423 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sun Nov  6 00:43:56 2016 done: Sun Nov  6 00:43:58 2016
 Total Scan time:  7.960 Total Display time: -0.020

Function used was FASTA [36.3.4 Apr, 2011]