Result of FASTA (omim) for
pFN21AE4405
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE4405, 419 aa
1>>>pF1KE4405 419 - 419 aa - 419 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.6053+/-0.000353; mu= 12.1776+/- 0.022
mean_var=109.1422+/-21.255, 0's: 0 Z-trim(115.8): 69 B-trim: 0 in 0/54
Lambda= 0.122766
statistics sampled from 26503 (26572) to 26503 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.662), E-opt: 0.2 (0.312), width: 16
Scan time: 7.450
The best scores are: opt bits E(85289)
NP_003209 (OMIM: 600951) telomeric repeat-binding ( 419) 2763 500.1 4.3e-141
XP_005251349 (OMIM: 600951) PREDICTED: telomeric r ( 449) 2145 390.6 4.1e-108
XP_016869281 (OMIM: 600951) PREDICTED: telomeric r ( 315) 2041 372.1 1.1e-102
XP_005251348 (OMIM: 600951) PREDICTED: telomeric r ( 469) 1965 358.8 1.7e-98
NP_059523 (OMIM: 600951) telomeric repeat-binding ( 439) 1963 358.4 2e-98
XP_011515884 (OMIM: 600951) PREDICTED: telomeric r ( 365) 1243 230.8 4.2e-60
XP_005256181 (OMIM: 602027) PREDICTED: telomeric r ( 464) 228 51.1 6.7e-06
XP_005256180 (OMIM: 602027) PREDICTED: telomeric r ( 541) 228 51.2 7.6e-06
NP_005643 (OMIM: 602027) telomeric repeat-binding ( 542) 228 51.2 7.7e-06
XP_005256179 (OMIM: 602027) PREDICTED: telomeric r ( 544) 228 51.2 7.7e-06
XP_005256178 (OMIM: 602027) PREDICTED: telomeric r ( 545) 228 51.2 7.7e-06
>>NP_003209 (OMIM: 600951) telomeric repeat-binding fact (419 aa)
initn: 2763 init1: 2763 opt: 2763 Z-score: 2654.0 bits: 500.1 E(85289): 4.3e-141
Smith-Waterman score: 2763; 100.0% identity (100.0% similar) in 419 aa overlap (1-419:1-419)
10 20 30 40 50 60
pF1KE4 MAEDVSSAAPSPRGCADGRDADPTEEQMAETERNDEEQFECQELLECQVQVGAPEEEEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MAEDVSSAAPSPRGCADGRDADPTEEQMAETERNDEEQFECQELLECQVQVGAPEEEEEE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 EEDAGLVAEAEAVAAGWMLDFLCLSLCRAFRDGRSEDFRRTRNSAEAIIHGLSSLTACQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 EEDAGLVAEAEAVAAGWMLDFLCLSLCRAFRDGRSEDFRRTRNSAEAIIHGLSSLTACQL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 RTIYICQFLTRIAAGKTLDAQFENDERITPLESALMIWGSIEKEHDKLHEEIQNLIKIQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 RTIYICQFLTRIAAGKTLDAQFENDERITPLESALMIWGSIEKEHDKLHEEIQNLIKIQA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 IAVCMENGNFKEAEEVFERIFGDPNSHMPFKSKLLMIISQKDTFHSFFQHFSYNHMMEKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 IAVCMENGNFKEAEEVFERIFGDPNSHMPFKSKLLMIISQKDTFHSFFQHFSYNHMMEKI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 KSYVNYVLSEKSSTFLMKAAAKVVESKRTRTITSQDKPSGNDVEMETEANLDTRKRSHKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 KSYVNYVLSEKSSTFLMKAAAKVVESKRTRTITSQDKPSGNDVEMETEANLDTRKRSHKN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 LFLSKLQHGTQQQDLNKKERRVGTPQSTKKKKESRRATESRIPVSKSQPVTPEKHRARKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LFLSKLQHGTQQQDLNKKERRVGTPQSTKKKKESRRATESRIPVSKSQPVTPEKHRARKR
310 320 330 340 350 360
370 380 390 400 410
pF1KE4 QAWLWEEDKNLRSGVRKYGEGNWSKILLHYKFNNRTSVMLKDRWRTMKKLKLISSDSED
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 QAWLWEEDKNLRSGVRKYGEGNWSKILLHYKFNNRTSVMLKDRWRTMKKLKLISSDSED
370 380 390 400 410
>>XP_005251349 (OMIM: 600951) PREDICTED: telomeric repea (449 aa)
initn: 2145 init1: 2145 opt: 2145 Z-score: 2062.0 bits: 390.6 E(85289): 4.1e-108
Smith-Waterman score: 2687; 93.1% identity (93.1% similar) in 449 aa overlap (1-419:1-449)
10 20 30 40 50 60
pF1KE4 MAEDVSSAAPSPRGCADGRDADPTEEQMAETERNDEEQFECQELLECQVQVGAPEEEEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MAEDVSSAAPSPRGCADGRDADPTEEQMAETERNDEEQFECQELLECQVQVGAPEEEEEE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 EEDAGLVAEAEAVAAGWMLDFLCLSLCRAFRDGRSEDFRRTRNSAEAIIHGLSSLTACQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EEDAGLVAEAEAVAAGWMLDFLCLSLCRAFRDGRSEDFRRTRNSAEAIIHGLSSLTACQL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 RTIYICQFLTRIAAGKTLDAQFENDERITPLESALMIWGSIEKEHDKLHEEIQNLIKIQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RTIYICQFLTRIAAGKTLDAQFENDERITPLESALMIWGSIEKEHDKLHEEIQNLIKIQA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 IAVCMENGNFKEAEEVFERIFGDPNSHMPFKSKLLMIISQKDTFHSFFQHFSYNHMMEKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IAVCMENGNFKEAEEVFERIFGDPNSHMPFKSKLLMIISQKDTFHSFFQHFSYNHMMEKI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 KSYVNYVLSEKSSTFLMKAAAKVVESKRTRTITSQDKPSGNDVEMETEANLDTRKRSHKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KSYVNYVLSEKSSTFLMKAAAKVVESKRTRTITSQDKPSGNDVEMETEANLDTRKRSHKN
250 260 270 280 290 300
310 320 330
pF1KE4 LFLSKLQHGTQQQDLNKKERRVGTPQ------------------------------STKK
:::::::::::::::::::::::::: :::
XP_005 LFLSKLQHGTQQQDLNKKERRVGTPQITYICLTKLTMNKKEGVRKGLCFLVLLKHYRTKK
310 320 330 340 350 360
340 350 360 370 380 390
pF1KE4 KKESRRATESRIPVSKSQPVTPEKHRARKRQAWLWEEDKNLRSGVRKYGEGNWSKILLHY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KKESRRATESRIPVSKSQPVTPEKHRARKRQAWLWEEDKNLRSGVRKYGEGNWSKILLHY
370 380 390 400 410 420
400 410
pF1KE4 KFNNRTSVMLKDRWRTMKKLKLISSDSED
:::::::::::::::::::::::::::::
XP_005 KFNNRTSVMLKDRWRTMKKLKLISSDSED
430 440
>>XP_016869281 (OMIM: 600951) PREDICTED: telomeric repea (315 aa)
initn: 2041 init1: 2041 opt: 2041 Z-score: 1964.7 bits: 372.1 E(85289): 1.1e-102
Smith-Waterman score: 2041; 100.0% identity (100.0% similar) in 312 aa overlap (108-419:4-315)
80 90 100 110 120 130
pF1KE4 MLDFLCLSLCRAFRDGRSEDFRRTRNSAEAIIHGLSSLTACQLRTIYICQFLTRIAAGKT
::::::::::::::::::::::::::::::
XP_016 MFTIIHGLSSLTACQLRTIYICQFLTRIAAGKT
10 20 30
140 150 160 170 180 190
pF1KE4 LDAQFENDERITPLESALMIWGSIEKEHDKLHEEIQNLIKIQAIAVCMENGNFKEAEEVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LDAQFENDERITPLESALMIWGSIEKEHDKLHEEIQNLIKIQAIAVCMENGNFKEAEEVF
40 50 60 70 80 90
200 210 220 230 240 250
pF1KE4 ERIFGDPNSHMPFKSKLLMIISQKDTFHSFFQHFSYNHMMEKIKSYVNYVLSEKSSTFLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ERIFGDPNSHMPFKSKLLMIISQKDTFHSFFQHFSYNHMMEKIKSYVNYVLSEKSSTFLM
100 110 120 130 140 150
260 270 280 290 300 310
pF1KE4 KAAAKVVESKRTRTITSQDKPSGNDVEMETEANLDTRKRSHKNLFLSKLQHGTQQQDLNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KAAAKVVESKRTRTITSQDKPSGNDVEMETEANLDTRKRSHKNLFLSKLQHGTQQQDLNK
160 170 180 190 200 210
320 330 340 350 360 370
pF1KE4 KERRVGTPQSTKKKKESRRATESRIPVSKSQPVTPEKHRARKRQAWLWEEDKNLRSGVRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KERRVGTPQSTKKKKESRRATESRIPVSKSQPVTPEKHRARKRQAWLWEEDKNLRSGVRK
220 230 240 250 260 270
380 390 400 410
pF1KE4 YGEGNWSKILLHYKFNNRTSVMLKDRWRTMKKLKLISSDSED
::::::::::::::::::::::::::::::::::::::::::
XP_016 YGEGNWSKILLHYKFNNRTSVMLKDRWRTMKKLKLISSDSED
280 290 300 310
>>XP_005251348 (OMIM: 600951) PREDICTED: telomeric repea (469 aa)
initn: 2537 init1: 1936 opt: 1965 Z-score: 1889.5 bits: 358.8 E(85289): 1.7e-98
Smith-Waterman score: 2518; 88.7% identity (88.7% similar) in 451 aa overlap (1-401:1-451)
10 20 30 40 50 60
pF1KE4 MAEDVSSAAPSPRGCADGRDADPTEEQMAETERNDEEQFECQELLECQVQVGAPEEEEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MAEDVSSAAPSPRGCADGRDADPTEEQMAETERNDEEQFECQELLECQVQVGAPEEEEEE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 EEDAGLVAEAEAVAAGWMLDFLCLSLCRAFRDGRSEDFRRTRNSAEAIIHGLSSLTACQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EEDAGLVAEAEAVAAGWMLDFLCLSLCRAFRDGRSEDFRRTRNSAEAIIHGLSSLTACQL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 RTIYICQFLTRIAAGKTLDAQFENDERITPLESALMIWGSIEKEHDKLHEEIQNLIKIQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RTIYICQFLTRIAAGKTLDAQFENDERITPLESALMIWGSIEKEHDKLHEEIQNLIKIQA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 IAVCMENGNFKEAEEVFERIFGDPNSHMPFKSKLLMIISQKDTFHSFFQHFSYNHMMEKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IAVCMENGNFKEAEEVFERIFGDPNSHMPFKSKLLMIISQKDTFHSFFQHFSYNHMMEKI
190 200 210 220 230 240
250 260 270 280 290
pF1KE4 KSYVNYVLSEKSSTFLMKAAAKVVESKRTRTITSQDKPSGNDVEMETEANLDTRK-----
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KSYVNYVLSEKSSTFLMKAAAKVVESKRTRTITSQDKPSGNDVEMETEANLDTRKSVSDK
250 260 270 280 290 300
300 310 320
pF1KE4 ---------------RSHKNLFLSKLQHGTQQQDLNKKERRVGTPQ--------------
:::::::::::::::::::::::::::::::
XP_005 QSAVTESSEGTVSLLRSHKNLFLSKLQHGTQQQDLNKKERRVGTPQITYICLTKLTMNKK
310 320 330 340 350 360
330 340 350 360 370
pF1KE4 ----------------STKKKKESRRATESRIPVSKSQPVTPEKHRARKRQAWLWEEDKN
:::::::::::::::::::::::::::::::::::::::::::
XP_005 EGVRKGLCFLVLLKHYRTKKKKESRRATESRIPVSKSQPVTPEKHRARKRQAWLWEEDKN
370 380 390 400 410 420
380 390 400 410
pF1KE4 LRSGVRKYGEGNWSKILLHYKFNNRTSVMLKDRWRTMKKLKLISSDSED
:::::::::::::::::::::::::::::::
XP_005 LRSGVRKYGEGNWSKILLHYKFNNRTSVMLKDRWRTMKKLKLISSDSED
430 440 450 460
>>NP_059523 (OMIM: 600951) telomeric repeat-binding fact (439 aa)
initn: 2749 init1: 1936 opt: 1963 Z-score: 1888.0 bits: 358.4 E(85289): 2e-98
Smith-Waterman score: 2713; 95.4% identity (95.4% similar) in 439 aa overlap (1-419:1-439)
10 20 30 40 50 60
pF1KE4 MAEDVSSAAPSPRGCADGRDADPTEEQMAETERNDEEQFECQELLECQVQVGAPEEEEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_059 MAEDVSSAAPSPRGCADGRDADPTEEQMAETERNDEEQFECQELLECQVQVGAPEEEEEE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 EEDAGLVAEAEAVAAGWMLDFLCLSLCRAFRDGRSEDFRRTRNSAEAIIHGLSSLTACQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_059 EEDAGLVAEAEAVAAGWMLDFLCLSLCRAFRDGRSEDFRRTRNSAEAIIHGLSSLTACQL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 RTIYICQFLTRIAAGKTLDAQFENDERITPLESALMIWGSIEKEHDKLHEEIQNLIKIQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_059 RTIYICQFLTRIAAGKTLDAQFENDERITPLESALMIWGSIEKEHDKLHEEIQNLIKIQA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 IAVCMENGNFKEAEEVFERIFGDPNSHMPFKSKLLMIISQKDTFHSFFQHFSYNHMMEKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_059 IAVCMENGNFKEAEEVFERIFGDPNSHMPFKSKLLMIISQKDTFHSFFQHFSYNHMMEKI
190 200 210 220 230 240
250 260 270 280 290
pF1KE4 KSYVNYVLSEKSSTFLMKAAAKVVESKRTRTITSQDKPSGNDVEMETEANLDTRK-----
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_059 KSYVNYVLSEKSSTFLMKAAAKVVESKRTRTITSQDKPSGNDVEMETEANLDTRKSVSDK
250 260 270 280 290 300
300 310 320 330 340
pF1KE4 ---------------RSHKNLFLSKLQHGTQQQDLNKKERRVGTPQSTKKKKESRRATES
:::::::::::::::::::::::::::::::::::::::::::::
NP_059 QSAVTESSEGTVSLLRSHKNLFLSKLQHGTQQQDLNKKERRVGTPQSTKKKKESRRATES
310 320 330 340 350 360
350 360 370 380 390 400
pF1KE4 RIPVSKSQPVTPEKHRARKRQAWLWEEDKNLRSGVRKYGEGNWSKILLHYKFNNRTSVML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_059 RIPVSKSQPVTPEKHRARKRQAWLWEEDKNLRSGVRKYGEGNWSKILLHYKFNNRTSVML
370 380 390 400 410 420
410
pF1KE4 KDRWRTMKKLKLISSDSED
:::::::::::::::::::
NP_059 KDRWRTMKKLKLISSDSED
430
>>XP_011515884 (OMIM: 600951) PREDICTED: telomeric repea (365 aa)
initn: 1815 init1: 1214 opt: 1243 Z-score: 1199.9 bits: 230.8 E(85289): 4.2e-60
Smith-Waterman score: 1796; 85.2% identity (85.2% similar) in 344 aa overlap (108-401:4-347)
80 90 100 110 120 130
pF1KE4 MLDFLCLSLCRAFRDGRSEDFRRTRNSAEAIIHGLSSLTACQLRTIYICQFLTRIAAGKT
::::::::::::::::::::::::::::::
XP_011 MFTIIHGLSSLTACQLRTIYICQFLTRIAAGKT
10 20 30
140 150 160 170 180 190
pF1KE4 LDAQFENDERITPLESALMIWGSIEKEHDKLHEEIQNLIKIQAIAVCMENGNFKEAEEVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LDAQFENDERITPLESALMIWGSIEKEHDKLHEEIQNLIKIQAIAVCMENGNFKEAEEVF
40 50 60 70 80 90
200 210 220 230 240 250
pF1KE4 ERIFGDPNSHMPFKSKLLMIISQKDTFHSFFQHFSYNHMMEKIKSYVNYVLSEKSSTFLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ERIFGDPNSHMPFKSKLLMIISQKDTFHSFFQHFSYNHMMEKIKSYVNYVLSEKSSTFLM
100 110 120 130 140 150
260 270 280 290
pF1KE4 KAAAKVVESKRTRTITSQDKPSGNDVEMETEANLDTRK--------------------RS
:::::::::::::::::::::::::::::::::::::: ::
XP_011 KAAAKVVESKRTRTITSQDKPSGNDVEMETEANLDTRKSVSDKQSAVTESSEGTVSLLRS
160 170 180 190 200 210
300 310 320
pF1KE4 HKNLFLSKLQHGTQQQDLNKKERRVGTPQ------------------------------S
:::::::::::::::::::::::::::::
XP_011 HKNLFLSKLQHGTQQQDLNKKERRVGTPQITYICLTKLTMNKKEGVRKGLCFLVLLKHYR
220 230 240 250 260 270
330 340 350 360 370 380
pF1KE4 TKKKKESRRATESRIPVSKSQPVTPEKHRARKRQAWLWEEDKNLRSGVRKYGEGNWSKIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TKKKKESRRATESRIPVSKSQPVTPEKHRARKRQAWLWEEDKNLRSGVRKYGEGNWSKIL
280 290 300 310 320 330
390 400 410
pF1KE4 LHYKFNNRTSVMLKDRWRTMKKLKLISSDSED
::::::::::::::
XP_011 LHYKFNNRTSVMLKDRWRTMKKLKLISSDSED
340 350 360
>>XP_005256181 (OMIM: 602027) PREDICTED: telomeric repea (464 aa)
initn: 331 init1: 202 opt: 228 Z-score: 226.9 bits: 51.1 E(85289): 6.7e-06
Smith-Waterman score: 335; 26.1% identity (54.5% similar) in 387 aa overlap (61-412:82-463)
40 50 60 70 80 90
pF1KE4 TERNDEEQFECQELLECQVQVGAPEEEEEEEEDAGLVAEAEAVAAGWMLDFLCLSLCRAF
:. :: . ::: :.: : :::
XP_005 GSGRAAGRRASRSSGRARRGRHEPGLGGPAERGAGEARLEEAVNR-WVLKFYFHEALRAF
60 70 80 90 100 110
100 110 120 130 140
pF1KE4 RDGRSEDFRRTRNSAEAI-IHGLSSLTACQLRTIYICQFLTRIAAGKTLDAQFENDERIT
: .: :::. :. .:. .. :.. . . : . . : :.:: :..:: .:. . ..:
XP_005 RGSRYGDFRQIRDIMQALLVRPLGKEHTVS-RLLRVMQCLSRIEEGENLDCSFDMEAELT
120 130 140 150 160
150 160 170 180 190 200
pF1KE4 PLESALMIWGSIEKEH---DKLHEEIQNLIK--IQAIAVCMENGNFKEAEEVFERIFGDP
:::::. . :. : . . : ..:.: . :. :.. . ..: . : :
XP_005 PLESAINVLEMIKTEFTLTEAVVESSRKLVKEAMAKKALKSESAASSTGKEDKQPAPG-P
170 180 190 200 210 220
210 220 230 240 250 260
pF1KE4 NSHMPFKSKLLMIISQKDTFHSFFQHFSYNHMMEKIKSYVNYV-LSEKSSTFLMKA--AA
. : . .. . :. . . ... . : . .. :..:. .. .: :.
XP_005 VEKPP-REPARQLRNPPTTIGMMTLKAAFKTLSGAQDSEAAFAKLDQKDLVLPTQALPAS
230 240 250 260 270 280
270 280 290 300 310 320
pF1KE4 KVVESKRTRTITSQDKPSGNDVEMETEANLDTRKRSHKNLFLSKLQHGTQQQ-DLNKKER
....:: : ... . : : .: . ... . . : : . ...:. . ::....
XP_005 PALKNKRPRK-DENESSAPADGEGGSELQPKNKRMTISRLVLEEDSQSTEPSAGLNSSQE
290 300 310 320 330 340
330 340 350
pF1KE4 RVGTPQST-----------------KKKKESRRATESR--------IPVSKSQPVTPEKH
...: : : : .: ..: . . .. :
XP_005 AASAPPSKPTVLNQPLPGEKNPKVPKGKWNSSNGVEEKETWVEEDELFQVQAAPDEDSTT
350 360 370 380 390 400
360 370 380 390 400 410
pF1KE4 RARKRQAWLWEEDKNLRSGVRKYGEGNWSKILLHYKFNNRTSVMLKDRWRTMKKLKLISS
:.: : ::.. ...::.:::::::. : .: : :::.::.::::::::.: .
XP_005 NITKKQKWTVEESEWVKAGVQKYGEGNWAAISKNYPFVNRTAVMIKDRWRTMKRLGMN
410 420 430 440 450 460
pF1KE4 DSED
>>XP_005256180 (OMIM: 602027) PREDICTED: telomeric repea (541 aa)
initn: 403 init1: 202 opt: 228 Z-score: 225.9 bits: 51.2 E(85289): 7.6e-06
Smith-Waterman score: 384; 26.2% identity (51.9% similar) in 447 aa overlap (77-412:97-540)
50 60 70 80 90 100
pF1KE4 CQVQVGAPEEEEEEEEDAGLVAEAEAVAAGWMLDFLCLSLCRAFRDGRSEDFRRTRNSAE
:.: : :::: .: :::. :. .
XP_005 RARRGRHEPGLGGPAERGAGEARLEEAVNRWVLKFYFHEALRAFRGSRYGDFRQIRDIMQ
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE4 AI-IHGLSSLTACQLRTIYICQFLTRIAAGKTLDAQFENDERITPLESALMIWGSIEKEH
:. .. :.. . . : . . : :.:: :..:: .:. . ..::::::. . :. :
XP_005 ALLVRPLGKEHTVS-RLLRVMQCLSRIEEGENLDCSFDMEAELTPLESAINVLEMIKTEF
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE4 ---DKLHEEIQNLIKIQAIAVCMENGNFKEAEEVFER-IFGDPNSHMPFKSKLLMIISQK
. . : ..:.: :. .:..: .:..: ..... . ::... ... :: :: .:
XP_005 TLTEAVVESSRKLVKEAAVIICIKNKEFEKASKILKKHMSKDPTTQ-KLRNDLLNIIREK
190 200 210 220 230 240
230 240 250 260 270
pF1KE4 DTFHSFFQHFSYNHMMEKIKSYVNYVLSEKSSTFLMKAAAKVVESKRTRTITSQ-DK-PS
. : .:.:::. ...:. ... :.. . .:. : :...:. . . :.. :: :.
XP_005 NLAHPVIQNFSYETFQQKMLRFLESHLDD-AEPYLLTMAKKALKSESAASSTGKEDKQPA
250 260 270 280 290 300
280 290 300 310
pF1KE4 GNDVEME------------TEANLDTRKRSHKNLFLSKLQHGT----QQQDL--------
. :: : .. : : . :.: .. .... .:.::
XP_005 PGPVEKPPREPARQLRNPPTTIGMMTLKAAFKTLSGAQDSEAAFAKLDQKDLVLPTQALP
310 320 330 340 350 360
320 330 340
pF1KE4 ------NKKERRVGTPQS--------TKKKKESRRATESRI-------------------
::. :. . .: .. . ...: : ::.
XP_005 ASPALKNKRPRKDENESSAPADGEGGSELQPKNKRMTISRLVLEEDSQSTEPSAGLNSSQ
370 380 390 400 410 420
350
pF1KE4 -----PVSK----SQPVTPEKH--------------------------------------
: :: .::. ::.
XP_005 EAASAPPSKPTVLNQPLPGEKNPKVPKGKWNSSNGVEEKETWVEEDELFQVQAPDEDSTT
430 440 450 460 470 480
360 370 380 390 400 410
pF1KE4 RARKRQAWLWEEDKNLRSGVRKYGEGNWSKILLHYKFNNRTSVMLKDRWRTMKKLKLISS
:.: : ::.. ...::.:::::::. : .: : :::.::.::::::::.: .
XP_005 NITKKQKWTVEESEWVKAGVQKYGEGNWAAISKNYPFVNRTAVMIKDRWRTMKRLGMN
490 500 510 520 530 540
pF1KE4 DSED
>>NP_005643 (OMIM: 602027) telomeric repeat-binding fact (542 aa)
initn: 403 init1: 202 opt: 228 Z-score: 225.9 bits: 51.2 E(85289): 7.7e-06
Smith-Waterman score: 367; 26.0% identity (51.7% similar) in 447 aa overlap (78-412:98-541)
50 60 70 80 90 100
pF1KE4 QVQVGAPEEEEEEEEDAGLVAEAEAVAAGWMLDFLCLSLCRAFRDGRSEDFRRTRNSAEA
.: : :::: .: :::. :. .:
NP_005 ARRGRHEPGLGGPAERGAGEARLEEAVNRWVLKFYFHEALRAFRGSRYGDFRQIRDIMQA
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE4 I-IHGLSSLTACQLRTIYICQFLTRIAAGKTLDAQFENDERITPLESALMIWGSIEKEH-
. .. :.. . . : . . : :.:: :..:: .:. . ..::::::. . :. :
NP_005 LLVRPLGKEHTVS-RLLRVMQCLSRIEEGENLDCSFDMEAELTPLESAINVLEMIKTEFT
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE4 --DKLHEEIQNLIKIQAIAVCMENGNFKEAEEVFER-IFGDPNSHMPFKSKLLMIISQKD
. . : ..:.: :. .:..: .:..: ..... . ::... ... :: :: .:.
NP_005 LTEAVVESSRKLVKEAAVIICIKNKEFEKASKILKKHMSKDPTTQ-KLRNDLLNIIREKN
190 200 210 220 230 240
230 240 250 260 270 280
pF1KE4 TFHSFFQHFSYNHMMEKIKSYVNYVLSEKSSTFLMKAAAKVVESKRTRTITSQ-DK-PSG
: .:.:::. ...:. ... :.. . .:. : :...:. . . :.. :: :.
NP_005 LAHPVIQNFSYETFQQKMLRFLESHLDD-AEPYLLTMAKKALKSESAASSTGKEDKQPAP
250 260 270 280 290 300
290 300 310
pF1KE4 NDVEME------------TEANLDTRKRSHKNLFLSKLQHGT----QQQDL---------
. :: : .. : : . :.: .. .... .:.::
NP_005 GPVEKPPREPARQLRNPPTTIGMMTLKAAFKTLSGAQDSEAAFAKLDQKDLVLPTQALPA
310 320 330 340 350 360
320 330 340
pF1KE4 -----NKKERRVGTPQS--------TKKKKESRRATESRI--------------------
::. :. . .: .. . ...: : ::.
NP_005 SPALKNKRPRKDENESSAPADGEGGSELQPKNKRMTISRLVLEEDSQSTEPSAGLNSSQE
370 380 390 400 410 420
350
pF1KE4 ----PVSK----SQPVTPEKH---------------------------------------
: :: .::. ::.
NP_005 AASAPPSKPTVLNQPLPGEKNPKVPKGKWNSSNGVEEKETWVEEDELFQVQAAPDEDSTT
430 440 450 460 470 480
360 370 380 390 400 410
pF1KE4 RARKRQAWLWEEDKNLRSGVRKYGEGNWSKILLHYKFNNRTSVMLKDRWRTMKKLKLISS
:.: : ::.. ...::.:::::::. : .: : :::.::.::::::::.: .
NP_005 NITKKQKWTVEESEWVKAGVQKYGEGNWAAISKNYPFVNRTAVMIKDRWRTMKRLGMN
490 500 510 520 530 540
pF1KE4 DSED
>>XP_005256179 (OMIM: 602027) PREDICTED: telomeric repea (544 aa)
initn: 390 init1: 202 opt: 228 Z-score: 225.9 bits: 51.2 E(85289): 7.7e-06
Smith-Waterman score: 354; 26.0% identity (50.6% similar) in 439 aa overlap (88-412:108-543)
60 70 80 90 100 110
pF1KE4 EEEEEDAGLVAEAEAVAAGWMLDFLCLSLCRAFRDGRSEDFRRTRNSAEAI-IHGLSSLT
:::: .: :::. :. .:. .. :..
XP_005 GGPAERGAGEARLEEAVNRWVLKFYFHEALRAFRGSRYGDFRQIRDIMQALLVRPLGKEH
80 90 100 110 120 130
120 130 140 150 160 170
pF1KE4 ACQLRTIYICQFLTRIAAGKTLDAQFENDERITPLESALMIWGSIEKEH---DKLHEEIQ
. . : . . : :.:: :..:: .:. . ..::::::. . :. : . . : .
XP_005 TVS-RLLRVMQCLSRIEEGENLDCSFDMEAELTPLESAINVLEMIKTEFTLTEAVVESSR
140 150 160 170 180 190
180 190 200 210 220 230
pF1KE4 NLIKIQAIAVCMENGNFKEAEEVFER-IFGDPNSHMPFKSKLLMIISQKDTFHSFFQHFS
.:.: :. .:..: .:..: ..... . ::... ... :: :: .:. : .:.::
XP_005 KLVKEAAVIICIKNKEFEKASKILKKHMSKDPTTQ-KLRNDLLNIIREKNLAHPVIQNFS
200 210 220 230 240 250
240 250 260 270 280
pF1KE4 YNHMMEKIKSYVNYVLSEK-----SSTFLMKAAAKVVESKRTRTITSQDKPSGNDVEME-
:. ...:. ... :.. . :. : : : :: . : . .:. . ::
XP_005 YETFQQKMLRFLESHLDDAEPYLLTIGFMAKKALKS-ESAASSTGKEDKQPAPGPVEKPP
260 270 280 290 300 310
290 300 310
pF1KE4 -----------TEANLDTRKRSHKNLFLSKLQHGT----QQQDL--------------NK
: .. : : . :.: .. .... .:.:: ::
XP_005 REPARQLRNPPTTIGMMTLKAAFKTLSGAQDSEAAFAKLDQKDLVLPTQALPASPALKNK
320 330 340 350 360 370
320 330 340
pF1KE4 KERRVGTPQS--------TKKKKESRRATESRI------------------------PVS
. :. . .: .. . ...: : ::. : :
XP_005 RPRKDENESSAPADGEGGSELQPKNKRMTISRLVLEEDSQSTEPSAGLNSSQEAASAPPS
380 390 400 410 420 430
350 360
pF1KE4 K----SQPVTPEKH--------------------------------------RARKRQAW
: .::. ::. :.: :
XP_005 KPTVLNQPLPGEKNPKVPKGKWNSSNGVEEKETWVEEDELFQVQAPDEDSTTNITKKQKW
440 450 460 470 480 490
370 380 390 400 410
pF1KE4 LWEEDKNLRSGVRKYGEGNWSKILLHYKFNNRTSVMLKDRWRTMKKLKLISSDSED
::.. ...::.:::::::. : .: : :::.::.::::::::.: .
XP_005 TVEESEWVKAGVQKYGEGNWAAISKNYPFVNRTAVMIKDRWRTMKRLGMN
500 510 520 530 540
419 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 01:19:50 2016 done: Sun Nov 6 01:19:51 2016
Total Scan time: 7.450 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]