Result of FASTA (omim) for
pFN21AE4396
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE4396, 417 aa
1>>>pF1KE4396 417 - 417 aa - 417 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.6171+/-0.000374; mu= 17.1293+/- 0.023
mean_var=147.6679+/-30.450, 0's: 0 Z-trim(117.3): 216 B-trim: 7 in 2/55
Lambda= 0.105543
statistics sampled from 28869 (29155) to 28869 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.703), E-opt: 0.2 (0.342), width: 16
Scan time: 9.320
The best scores are: opt bits E(85289)
NP_006496 (OMIM: 173850) poliovirus receptor isofo ( 417) 2825 442.2 1.2e-123
NP_001129242 (OMIM: 173850) poliovirus receptor is ( 392) 2631 412.6 8.7e-115
NP_001129240 (OMIM: 173850) poliovirus receptor is ( 372) 2300 362.2 1.3e-99
NP_001129241 (OMIM: 173850) poliovirus receptor is ( 364) 2242 353.3 5.6e-97
NP_002847 (OMIM: 600798) nectin-2 isoform alpha pr ( 479) 1008 165.6 2.4e-40
NP_001036189 (OMIM: 600798) nectin-2 isoform delta ( 538) 1006 165.4 3.2e-40
XP_011525494 (OMIM: 600798) PREDICTED: nectin-2 is ( 369) 979 161.0 4.4e-39
NP_976030 (OMIM: 225060,600644) nectin-1 isoform 2 ( 458) 657 112.1 2.9e-24
NP_002846 (OMIM: 225060,600644) nectin-1 isoform 1 ( 517) 650 111.1 6.5e-24
NP_976031 (OMIM: 225060,600644) nectin-1 isoform 3 ( 352) 615 105.6 2.1e-22
XP_016861615 (OMIM: 607147) PREDICTED: nectin-3 is ( 510) 550 95.9 2.5e-19
NP_001230217 (OMIM: 607147) nectin-3 isoform 3 [Ho ( 487) 546 95.2 3.7e-19
XP_016861612 (OMIM: 607147) PREDICTED: nectin-3 is ( 541) 544 95.0 4.8e-19
NP_056295 (OMIM: 607147) nectin-3 isoform 1 precur ( 549) 532 93.2 1.7e-18
XP_016861614 (OMIM: 607147) PREDICTED: nectin-3 is ( 526) 528 92.6 2.6e-18
XP_016861613 (OMIM: 607147) PREDICTED: nectin-3 is ( 534) 526 92.3 3.2e-18
XP_011510965 (OMIM: 607147) PREDICTED: nectin-3 is ( 580) 526 92.3 3.4e-18
NP_001230215 (OMIM: 607147) nectin-3 isoform 2 pre ( 366) 520 91.1 4.8e-18
XP_005245565 (OMIM: 609607,613573) PREDICTED: nect ( 485) 474 84.3 7.3e-16
NP_112178 (OMIM: 609607,613573) nectin-4 precursor ( 510) 474 84.3 7.5e-16
XP_011508325 (OMIM: 609607,613573) PREDICTED: nect ( 460) 473 84.1 7.9e-16
XP_011508324 (OMIM: 609607,613573) PREDICTED: nect ( 486) 473 84.1 8.1e-16
XP_011508323 (OMIM: 609607,613573) PREDICTED: nect ( 511) 473 84.2 8.4e-16
NP_001120645 (OMIM: 609743) cell adhesion molecule ( 398) 349 65.1 3.5e-10
NP_067012 (OMIM: 609743) cell adhesion molecule 3 ( 432) 349 65.2 3.7e-10
XP_016861616 (OMIM: 607147) PREDICTED: nectin-3 is ( 337) 315 59.9 1.1e-08
XP_006713145 (OMIM: 609938) PREDICTED: cell adhesi ( 395) 313 59.6 1.6e-08
XP_016861552 (OMIM: 609938) PREDICTED: cell adhesi ( 397) 313 59.7 1.6e-08
NP_001161147 (OMIM: 609938) cell adhesion molecule ( 404) 313 59.7 1.6e-08
NP_001091987 (OMIM: 605686) cell adhesion molecule ( 414) 311 59.4 2e-08
XP_006713144 (OMIM: 609938) PREDICTED: cell adhesi ( 435) 296 57.1 9.9e-08
NP_001161146 (OMIM: 609938) cell adhesion molecule ( 435) 296 57.1 9.9e-08
NP_694854 (OMIM: 609938) cell adhesion molecule 2 ( 437) 296 57.1 9.9e-08
XP_016861551 (OMIM: 609938) PREDICTED: cell adhesi ( 449) 296 57.1 1e-07
XP_016872947 (OMIM: 605686) PREDICTED: cell adhesi ( 402) 294 56.8 1.2e-07
NP_055148 (OMIM: 605686) cell adhesion molecule 1 ( 442) 294 56.8 1.2e-07
NP_001287973 (OMIM: 605686) cell adhesion molecule ( 453) 294 56.8 1.3e-07
NP_001287972 (OMIM: 605686) cell adhesion molecule ( 471) 294 56.9 1.3e-07
XP_016872946 (OMIM: 605686) PREDICTED: cell adhesi ( 477) 294 56.9 1.3e-07
XP_005271551 (OMIM: 605686) PREDICTED: cell adhesi ( 425) 284 55.3 3.5e-07
NP_001287974 (OMIM: 605686) cell adhesion molecule ( 443) 284 55.3 3.6e-07
XP_016881941 (OMIM: 609744) PREDICTED: cell adhesi ( 369) 274 53.7 9.2e-07
NP_660339 (OMIM: 609744) cell adhesion molecule 4 ( 388) 274 53.7 9.4e-07
NP_954648 (OMIM: 607762) kin of IRRE-like protein ( 583) 268 53.0 2.3e-06
NP_115499 (OMIM: 607762) kin of IRRE-like protein ( 633) 268 53.1 2.4e-06
XP_011525667 (OMIM: 607762) PREDICTED: kin of IRRE ( 658) 268 53.1 2.4e-06
NP_001316459 (OMIM: 607762) kin of IRRE-like prote ( 658) 268 53.1 2.4e-06
XP_016882837 (OMIM: 607762) PREDICTED: kin of IRRE ( 673) 268 53.1 2.5e-06
NP_954649 (OMIM: 607762) kin of IRRE-like protein ( 708) 268 53.1 2.5e-06
XP_011525665 (OMIM: 607762) PREDICTED: kin of IRRE ( 708) 268 53.1 2.5e-06
>>NP_006496 (OMIM: 173850) poliovirus receptor isoform a (417 aa)
initn: 2825 init1: 2825 opt: 2825 Z-score: 2341.1 bits: 442.2 E(85289): 1.2e-123
Smith-Waterman score: 2825; 100.0% identity (100.0% similar) in 417 aa overlap (1-417:1-417)
10 20 30 40 50 60
pF1KE4 MARAMAAAWPLLLVALLVLSWPPPGTGDVVVQAPTQVPGFLGDSVTLPCYLQVPNMEVTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MARAMAAAWPLLLVALLVLSWPPPGTGDVVVQAPTQVPGFLGDSVTLPCYLQVPNMEVTH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 VSQLTWARHGESGSMAVFHQTQGPSYSESKRLEFVAARLGAELRNASLRMFGLRVEDEGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 VSQLTWARHGESGSMAVFHQTQGPSYSESKRLEFVAARLGAELRNASLRMFGLRVEDEGN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 YTCLFVTFPQGSRSVDIWLRVLAKPQNTAEVQKVQLTGEPVPMARCVSTGGRPPAQITWH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 YTCLFVTFPQGSRSVDIWLRVLAKPQNTAEVQKVQLTGEPVPMARCVSTGGRPPAQITWH
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 SDLGGMPNTSQVPGFLSGTVTVTSLWILVPSSQVDGKNVTCKVEHESFEKPQLLTVNLTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 SDLGGMPNTSQVPGFLSGTVTVTSLWILVPSSQVDGKNVTCKVEHESFEKPQLLTVNLTV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 YYPPEVSISGYDNNWYLGQNEATLTCDARSNPEPTGYNWSTTMGPLPPFAVAQGAQLLIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 YYPPEVSISGYDNNWYLGQNEATLTCDARSNPEPTGYNWSTTMGPLPPFAVAQGAQLLIR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 PVDKPINTTLICNVTNALGARQAELTVQVKEGPPSEHSGMSRNAIIFLVLGILVFLILLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 PVDKPINTTLICNVTNALGARQAELTVQVKEGPPSEHSGMSRNAIIFLVLGILVFLILLG
310 320 330 340 350 360
370 380 390 400 410
pF1KE4 IGIYFYWSKCSREVLWHCHLCPSSTEHASASANGHVSYSAVSRENSSSQDPQTEGTR
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 IGIYFYWSKCSREVLWHCHLCPSSTEHASASANGHVSYSAVSRENSSSQDPQTEGTR
370 380 390 400 410
>>NP_001129242 (OMIM: 173850) poliovirus receptor isofor (392 aa)
initn: 2698 init1: 2631 opt: 2631 Z-score: 2181.8 bits: 412.6 E(85289): 8.7e-115
Smith-Waterman score: 2631; 99.2% identity (99.5% similar) in 389 aa overlap (1-389:1-389)
10 20 30 40 50 60
pF1KE4 MARAMAAAWPLLLVALLVLSWPPPGTGDVVVQAPTQVPGFLGDSVTLPCYLQVPNMEVTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MARAMAAAWPLLLVALLVLSWPPPGTGDVVVQAPTQVPGFLGDSVTLPCYLQVPNMEVTH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 VSQLTWARHGESGSMAVFHQTQGPSYSESKRLEFVAARLGAELRNASLRMFGLRVEDEGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VSQLTWARHGESGSMAVFHQTQGPSYSESKRLEFVAARLGAELRNASLRMFGLRVEDEGN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 YTCLFVTFPQGSRSVDIWLRVLAKPQNTAEVQKVQLTGEPVPMARCVSTGGRPPAQITWH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YTCLFVTFPQGSRSVDIWLRVLAKPQNTAEVQKVQLTGEPVPMARCVSTGGRPPAQITWH
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 SDLGGMPNTSQVPGFLSGTVTVTSLWILVPSSQVDGKNVTCKVEHESFEKPQLLTVNLTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SDLGGMPNTSQVPGFLSGTVTVTSLWILVPSSQVDGKNVTCKVEHESFEKPQLLTVNLTV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 YYPPEVSISGYDNNWYLGQNEATLTCDARSNPEPTGYNWSTTMGPLPPFAVAQGAQLLIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YYPPEVSISGYDNNWYLGQNEATLTCDARSNPEPTGYNWSTTMGPLPPFAVAQGAQLLIR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 PVDKPINTTLICNVTNALGARQAELTVQVKEGPPSEHSGMSRNAIIFLVLGILVFLILLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PVDKPINTTLICNVTNALGARQAELTVQVKEGPPSEHSGMSRNAIIFLVLGILVFLILLG
310 320 330 340 350 360
370 380 390 400 410
pF1KE4 IGIYFYWSKCSREVLWHCHLCPSSTEHASASANGHVSYSAVSRENSSSQDPQTEGTR
:::::::::::::::::::::::: .: :
NP_001 IGIYFYWSKCSREVLWHCHLCPSSEHHQSCRN
370 380 390
>>NP_001129240 (OMIM: 173850) poliovirus receptor isofor (372 aa)
initn: 2300 init1: 2300 opt: 2300 Z-score: 1909.6 bits: 362.2 E(85289): 1.3e-99
Smith-Waterman score: 2407; 89.2% identity (89.2% similar) in 417 aa overlap (1-417:1-372)
10 20 30 40 50 60
pF1KE4 MARAMAAAWPLLLVALLVLSWPPPGTGDVVVQAPTQVPGFLGDSVTLPCYLQVPNMEVTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MARAMAAAWPLLLVALLVLSWPPPGTGDVVVQAPTQVPGFLGDSVTLPCYLQVPNMEVTH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 VSQLTWARHGESGSMAVFHQTQGPSYSESKRLEFVAARLGAELRNASLRMFGLRVEDEGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VSQLTWARHGESGSMAVFHQTQGPSYSESKRLEFVAARLGAELRNASLRMFGLRVEDEGN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 YTCLFVTFPQGSRSVDIWLRVLAKPQNTAEVQKVQLTGEPVPMARCVSTGGRPPAQITWH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YTCLFVTFPQGSRSVDIWLRVLAKPQNTAEVQKVQLTGEPVPMARCVSTGGRPPAQITWH
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 SDLGGMPNTSQVPGFLSGTVTVTSLWILVPSSQVDGKNVTCKVEHESFEKPQLLTVNLTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SDLGGMPNTSQVPGFLSGTVTVTSLWILVPSSQVDGKNVTCKVEHESFEKPQLLTVNLTV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 YYPPEVSISGYDNNWYLGQNEATLTCDARSNPEPTGYNWSTTMGPLPPFAVAQGAQLLIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YYPPEVSISGYDNNWYLGQNEATLTCDARSNPEPTGYNWSTTMGPLPPFAVAQGAQLLIR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 PVDKPINTTLICNVTNALGARQAELTVQVKEGPPSEHSGMSRNAIIFLVLGILVFLILLG
:::::::::::::::::::::::::::::::::::::::
NP_001 PVDKPINTTLICNVTNALGARQAELTVQVKEGPPSEHSG---------------------
310 320 330
370 380 390 400 410
pF1KE4 IGIYFYWSKCSREVLWHCHLCPSSTEHASASANGHVSYSAVSRENSSSQDPQTEGTR
:::::::::::::::::::::::::::::::::
NP_001 ------------------------TEHASASANGHVSYSAVSRENSSSQDPQTEGTR
340 350 360 370
>>NP_001129241 (OMIM: 173850) poliovirus receptor isofor (364 aa)
initn: 2425 init1: 2232 opt: 2242 Z-score: 1862.0 bits: 353.3 E(85289): 5.6e-97
Smith-Waterman score: 2323; 87.1% identity (87.3% similar) in 417 aa overlap (1-417:1-364)
10 20 30 40 50 60
pF1KE4 MARAMAAAWPLLLVALLVLSWPPPGTGDVVVQAPTQVPGFLGDSVTLPCYLQVPNMEVTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MARAMAAAWPLLLVALLVLSWPPPGTGDVVVQAPTQVPGFLGDSVTLPCYLQVPNMEVTH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 VSQLTWARHGESGSMAVFHQTQGPSYSESKRLEFVAARLGAELRNASLRMFGLRVEDEGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VSQLTWARHGESGSMAVFHQTQGPSYSESKRLEFVAARLGAELRNASLRMFGLRVEDEGN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 YTCLFVTFPQGSRSVDIWLRVLAKPQNTAEVQKVQLTGEPVPMARCVSTGGRPPAQITWH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YTCLFVTFPQGSRSVDIWLRVLAKPQNTAEVQKVQLTGEPVPMARCVSTGGRPPAQITWH
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 SDLGGMPNTSQVPGFLSGTVTVTSLWILVPSSQVDGKNVTCKVEHESFEKPQLLTVNLTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SDLGGMPNTSQVPGFLSGTVTVTSLWILVPSSQVDGKNVTCKVEHESFEKPQLLTVNLTV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 YYPPEVSISGYDNNWYLGQNEATLTCDARSNPEPTGYNWSTTMGPLPPFAVAQGAQLLIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YYPPEVSISGYDNNWYLGQNEATLTCDARSNPEPTGYNWSTTMGPLPPFAVAQGAQLLIR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 PVDKPINTTLICNVTNALGARQAELTVQVKEGPPSEHSGMSRNAIIFLVLGILVFLILLG
::::::::::::::::::::::::::::::
NP_001 PVDKPINTTLICNVTNALGARQAELTVQVK------------------------------
310 320 330
370 380 390 400 410
pF1KE4 IGIYFYWSKCSREVLWHCHLCPSSTEHASASANGHVSYSAVSRENSSSQDPQTEGTR
.:::::::::::::::::::::::::::::::::
NP_001 -----------------------GTEHASASANGHVSYSAVSRENSSSQDPQTEGTR
340 350 360
>>NP_002847 (OMIM: 600798) nectin-2 isoform alpha precur (479 aa)
initn: 1120 init1: 956 opt: 1008 Z-score: 845.2 bits: 165.6 E(85289): 2.4e-40
Smith-Waterman score: 1135; 49.6% identity (72.3% similar) in 379 aa overlap (9-372:19-389)
10 20 30 40 50
pF1KE4 MARAMAAAWPLLLVALLVLSWPPPGTGDVVVQAPTQVPGFLGDSVTLPCY
:::::. :: :. :: ::. .: : :: .: :::.
NP_002 MARAAALLPSRSPPTPLLWPLLLLLLL-----ETGAQDVRVQVLPEVRGQLGGTVELPCH
10 20 30 40 50
60 70 80 90 100
pF1KE4 LQVPNMEVTHVSQLTWARHGESGS---MAVFHQTQGPSYSE----SKRLEFVAARLG---
: .: . ..: .:: : .. .:.:: .:::. :.:: ::.:. .
NP_002 L-LPPVPGLYISLVTWQRPDAPANHQNVAAFHPKMGPSFPSPKPGSERLSFVSAKQSTGQ
60 70 80 90 100 110
110 120 130 140 150
pF1KE4 ---AELRNASLRMFGLRVEDEGNYTCLFVTFPQGSRSVDIWLRVLAKPQNTAEVQKVQLT
:::..:.: . :: ::::::::: :.:::.:: ::::.:::.: ::.::: ..
NP_002 DTEAELQDATLALHGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQKVTFS
120 130 140 150 160 170
160 170 180 190 200 210
pF1KE4 GEPVPMARCVSTGGRPPAQITWHSDLGGMPNTSQVPGFLSGTVTVTSLWILVPSSQVDGK
.:. .: :.: :::::.:.: :.: . .:: : :.::::::: . ::::...::
NP_002 QDPTTVALCISKEGRPPARISWLSSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGRADGV
180 190 200 210 220 230
220 230 240 250 260 270
pF1KE4 NVTCKVEHESFEKPQLLTVNLTVYYPPEVSISGYDNNWYLGQNEATLTCDARSNPEPTGY
.:::::::::::.: :. :.:.: :::::::::::.:::::...:::.::.:::::::::
NP_002 TVTCKVEHESFEEPALIPVTLSVRYPPEVSISGYDDNWYLGRTDATLSCDVRSNPEPTGY
240 250 260 270 280 290
280 290 300 310 320 330
pF1KE4 NWSTTMGPLPPFAVAQGAQLLIRPVDKPINTTLICNVTNALGARQAELTVQVKEGPPSEH
.:::: : .: :::::.::.:. ::. .:::..:.::::.: .:: .. :.: : .
NP_002 DWSTTSGTFPTSAVAQGSQLVIHAVDSLFNTTFVCTVTNAVGMGRAEQVIFVRETPRA--
300 310 320 330 340 350
340 350 360 370 380 390
pF1KE4 SGMSRNAIIFLVLG--ILVFLILLGIGIYFYWSKCSREVLWHCHLCPSSTEHASASANGH
: . . ... ..: .::.:.: : .. : . :
NP_002 SPRDVGPLVWGAVGGTLLVLLLLAGGSLAFILLRVRRRRKSPGGAGGGASGDGGFYDPKA
360 370 380 390 400 410
400 410
pF1KE4 VSYSAVSRENSSSQDPQTEGTR
NP_002 QVLGNGDPVFWTPVVPGPMEPDGKDEEEEEEEEKAEKGLMLPPPPALEDDMESQLDGSLI
420 430 440 450 460 470
>>NP_001036189 (OMIM: 600798) nectin-2 isoform delta pre (538 aa)
initn: 1152 init1: 964 opt: 1006 Z-score: 843.1 bits: 165.4 E(85289): 3.2e-40
Smith-Waterman score: 1133; 50.0% identity (72.8% similar) in 368 aa overlap (9-363:19-379)
10 20 30 40 50
pF1KE4 MARAMAAAWPLLLVALLVLSWPPPGTGDVVVQAPTQVPGFLGDSVTLPCY
:::::. :: :. :: ::. .: : :: .: :::.
NP_001 MARAAALLPSRSPPTPLLWPLLLLLLL-----ETGAQDVRVQVLPEVRGQLGGTVELPCH
10 20 30 40 50
60 70 80 90 100
pF1KE4 LQVPNMEVTHVSQLTWARHGESGS---MAVFHQTQGPSYSE----SKRLEFVAARLG---
: .: . ..: .:: : .. .:.:: .:::. :.:: ::.:. .
NP_001 L-LPPVPGLYISLVTWQRPDAPANHQNVAAFHPKMGPSFPSPKPGSERLSFVSAKQSTGQ
60 70 80 90 100 110
110 120 130 140 150
pF1KE4 ---AELRNASLRMFGLRVEDEGNYTCLFVTFPQGSRSVDIWLRVLAKPQNTAEVQKVQLT
:::..:.: . :: ::::::::: :.:::.:: ::::.:::.: ::.::: ..
NP_001 DTEAELQDATLALHGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQKVTFS
120 130 140 150 160 170
160 170 180 190 200 210
pF1KE4 GEPVPMARCVSTGGRPPAQITWHSDLGGMPNTSQVPGFLSGTVTVTSLWILVPSSQVDGK
.:. .: :.: :::::.:.: :.: . .:: : :.::::::: . ::::...::
NP_001 QDPTTVALCISKEGRPPARISWLSSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGRADGV
180 190 200 210 220 230
220 230 240 250 260 270
pF1KE4 NVTCKVEHESFEKPQLLTVNLTVYYPPEVSISGYDNNWYLGQNEATLTCDARSNPEPTGY
.:::::::::::.: :. :.:.: :::::::::::.:::::...:::.::.:::::::::
NP_001 TVTCKVEHESFEEPALIPVTLSVRYPPEVSISGYDDNWYLGRTDATLSCDVRSNPEPTGY
240 250 260 270 280 290
280 290 300 310 320 330
pF1KE4 NWSTTMGPLPPFAVAQGAQLLIRPVDKPINTTLICNVTNALGARQAELTVQVKEGPPSEH
.:::: : .: :::::.::.:. ::. .:::..:.::::.: .:: .. :.: : .
NP_001 DWSTTSGTFPTSAVAQGSQLVIHAVDSLFNTTFVCTVTNAVGMGRAEQVIFVRETPNTAG
300 310 320 330 340 350
340 350 360 370 380 390
pF1KE4 SGMSRNAIIFLVLGILVFLILLGIGIYFYWSKCSREVLWHCHLCPSSTEHASASANGHVS
.: . ..:: ... .. . . ::
NP_001 AGAT-GGIIGGIIAAIIATAVAATGILICRQQRKEQTLQGAEEDEDLEGPPSYKPPTPKA
360 370 380 390 400 410
>>XP_011525494 (OMIM: 600798) PREDICTED: nectin-2 isofor (369 aa)
initn: 1106 init1: 942 opt: 979 Z-score: 822.6 bits: 161.0 E(85289): 4.4e-39
Smith-Waterman score: 1106; 51.3% identity (73.0% similar) in 355 aa overlap (9-345:19-367)
10 20 30 40 50
pF1KE4 MARAMAAAWPLLLVALLVLSWPPPGTGDVVVQAPTQVPGFLGDSVTLPCY
:::::. :: :. :: ::. .: : :: .: :::.
XP_011 MARAAALLPSRSPPTPLLWPLLLLLLL-----ETGAQDVRVQVLPEVRGQLGGTVELPCH
10 20 30 40 50
60 70 80 90 100
pF1KE4 LQVPNMEVTHVSQLTWARHGESGS---MAVFHQTQGPSYSE----SKRLEFVAARLG---
: .: . ..: .:: : .. .:.:: .:::. :.:: ::.:. .
XP_011 L-LPPVPGLYISLVTWQRPDAPANHQNVAAFHPKMGPSFPSPKPGSERLSFVSAKQSTGQ
60 70 80 90 100 110
110 120 130 140 150
pF1KE4 ---AELRNASLRMFGLRVEDEGNYTCLFVTFPQGSRSVDIWLRVLAKPQNTAEVQKVQLT
:::..:.: . :: ::::::::: :.:::.:: ::::.:::.: ::.::: ..
XP_011 DTEAELQDATLALHGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQKVTFS
120 130 140 150 160 170
160 170 180 190 200 210
pF1KE4 GEPVPMARCVSTGGRPPAQITWHSDLGGMPNTSQVPGFLSGTVTVTSLWILVPSSQVDGK
.:. .: :.: :::::.:.: :.: . .:: : :.::::::: . ::::...::
XP_011 QDPTTVALCISKEGRPPARISWLSSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGRADGV
180 190 200 210 220 230
220 230 240 250 260 270
pF1KE4 NVTCKVEHESFEKPQLLTVNLTVYYPPEVSISGYDNNWYLGQNEATLTCDARSNPEPTGY
.:::::::::::.: :. :.:.: :::::::::::.:::::...:::.::.:::::::::
XP_011 TVTCKVEHESFEEPALIPVTLSVRYPPEVSISGYDDNWYLGRTDATLSCDVRSNPEPTGY
240 250 260 270 280 290
280 290 300 310 320 330
pF1KE4 NWSTTMGPLPPFAVAQGAQLLIRPVDKPINTTLICNVTNALGARQAELTVQVK---EGPP
.:::: : .: :::::.::.:. ::. .:::..:.::::.: .:: .. :. .
XP_011 DWSTTSGTFPTSAVAQGSQLVIHAVDSLFNTTFVCTVTNAVGMGRAEQVIFVRALEDDME
300 310 320 330 340 350
340 350 360 370 380 390
pF1KE4 SEHSG--MSRNAIIFLVLGILVFLILLGIGIYFYWSKCSREVLWHCHLCPSSTEHASASA
:. .: .:: :.
XP_011 SQLDGSLISRRAVYV
360
>>NP_976030 (OMIM: 225060,600644) nectin-1 isoform 2 pre (458 aa)
initn: 477 init1: 183 opt: 657 Z-score: 556.6 bits: 112.1 E(85289): 2.9e-24
Smith-Waterman score: 657; 32.6% identity (64.2% similar) in 380 aa overlap (1-369:6-372)
10 20 30 40 50
pF1KE4 MARAMAAAWPLLLVALLVLSWPPPGTGDVVVQAPTQVPGFLGDSVTLPCYLQVPN
.: : . : : :: . .. ::. . :::. .. ::.: .:.: : . :
NP_976 MARMGLAGAAGRWWGL---ALGLTAFFLPGVHSQVVQVNDSMYGFIGTDVVLHCSFANP-
10 20 30 40 50
60 70 80 90 100 110
pF1KE4 MEVTHVSQLTWAR--HGESGSMAVFHQTQGPSY--SESKRLEFVAARLGAELRNASLRMF
. ....:.:: . .: . ..:... ..: : .:.:: : . ....:.
NP_976 LPSVKITQVTWQKSTNGSKQNVAIYNPSMGVSVLAPYRERVEF----LRPSFTDGTIRLS
60 70 80 90 100 110
120 130 140 150 160
pF1KE4 GLRVEDEGNYTCLFVTFPQGSRSVDIWLRVLAKPQNTAEVQKVQLTG-----EPVPMARC
:..:::: : : :.::: :.: .. : :.::: : : .. : . . : .: :
NP_976 RLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVLVATC
120 130 140 150 160 170
170 180 190 200 210 220
pF1KE4 VSTGGRPPAQITWHSDLGGMPNTSQVPGFLSGTVTVTSLWILVPSSQVDGKNVTCKVEHE
.:..:.::. ..:.. : : . ... . .::::: : . :::: .. ....: :...
NP_976 TSANGKPPSVVSWETRLKGEAEYQEIRNP-NGTVTVISRYRLVPSREAHQQSLACIVNYH
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE4 SFEKPQLLTVNLTVYYPPEVSISGYDNNWYLGQNEATLTCDARSNPEPTGYNWSTTMGPL
. . ::.: : : :::.: :.:.:::: . .. ::: : .:: : :.:.: : :
NP_976 MDRFKESLTLN--VQYEPEVTIEGFDGNWYLQRMDVKLTCKADANPPATEYHWTTLNGSL
240 250 260 270 280
290 300 310 320 330 340
pF1KE4 PPFAVAQGAQLLIR-PVDKPINTTLICNVTNALGARQAELTVQVKEGPPSEHSGMSRNAI
: . ::. :... :.. . : ::..:: .:.:.... :.. : : . :.. .:
NP_976 PKGVEAQNRTLFFKGPINYSLAGTYICEATNPIGTRSGQVEVNITE-KPRPQRGLG-SAA
290 300 310 320 330 340
350 360 370 380 390 400
pF1KE4 IFLVLGILVFLILLGI-GIYFYWSKCSREVLWHCHLCPSSTEHASASANGHVSYSAVSRE
.:. . :::::... ..: ...
NP_976 RLLAGTVAVFLILVAVLTVFFLYNRQQKSPPETDGAGTDQPLSQKPEPSPSRQSSLVPED
350 360 370 380 390 400
>>NP_002846 (OMIM: 225060,600644) nectin-1 isoform 1 pre (517 aa)
initn: 475 init1: 183 opt: 650 Z-score: 550.3 bits: 111.1 E(85289): 6.5e-24
Smith-Waterman score: 655; 34.4% identity (63.3% similar) in 381 aa overlap (1-363:6-374)
10 20 30 40 50
pF1KE4 MARAMAAAWPLLLVALLVLSWPPPGTGDVVVQAPTQVPGFLGDSVTLPCYLQVPN
.: : . : : :: . .. ::. . :::. .. ::.: .:.: : . :
NP_002 MARMGLAGAAGRWWGL---ALGLTAFFLPGVHSQVVQVNDSMYGFIGTDVVLHCSFANP-
10 20 30 40 50
60 70 80 90 100 110
pF1KE4 MEVTHVSQLTWAR--HGESGSMAVFHQTQGPSY--SESKRLEFVAARLGAELRNASLRMF
. ....:.:: . .: . ..:... ..: : .:.:: : . ....:.
NP_002 LPSVKITQVTWQKSTNGSKQNVAIYNPSMGVSVLAPYRERVEF----LRPSFTDGTIRLS
60 70 80 90 100 110
120 130 140 150 160
pF1KE4 GLRVEDEGNYTCLFVTFPQGSRSVDIWLRVLAKPQNTAEVQKVQLTG-----EPVPMARC
:..:::: : : :.::: :.: .. : :.::: : : .. : . . : .: :
NP_002 RLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVLVATC
120 130 140 150 160 170
170 180 190 200 210 220
pF1KE4 VSTGGRPPAQITWHSDLGGMPNTSQVPGFLSGTVTVTSLWILVPSSQVDGKNVTCKVEHE
.:..:.::. ..:.. : : . ... . .::::: : . :::: .. ....: :...
NP_002 TSANGKPPSVVSWETRLKGEAEYQEIRNP-NGTVTVISRYRLVPSREAHQQSLACIVNYH
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE4 SFEKPQLLTVNLTVYYPPEVSISGYDNNWYLGQNEATLTCDARSNPEPTGYNWSTTMGPL
. . ::.: : : :::.: :.:.:::: . .. ::: : .:: : :.:.: : :
NP_002 MDRFKESLTLN--VQYEPEVTIEGFDGNWYLQRMDVKLTCKADANPPATEYHWTTLNGSL
240 250 260 270 280
290 300 310 320 330
pF1KE4 PPFAVAQGAQLLIR-PVDKPINTTLICNVTNALGARQAELTVQVKEGP----PSEH---S
: . ::. :... :.. . : ::..:: .:.:.... :.. : : : :: .
NP_002 PKGVEAQNRTLFFKGPINYSLAGTYICEATNPIGTRSGQVEVNITEFPYTPSPPEHGRRA
290 300 310 320 330 340
340 350 360 370 380 390
pF1KE4 GMSRNAIIFLVLG-ILVFLILLGIGIYFYWSKCSREVLWHCHLCPSSTEHASASANGHVS
: .::: : : ::. ::..: ::
NP_002 GPVPTAIIGGVAGSILLVLIVVG-GIVVALRRRRHTFKGDYSTKKHVYGNGYSKAGIPQH
350 360 370 380 390 400
>>NP_976031 (OMIM: 225060,600644) nectin-1 isoform 3 pre (352 aa)
initn: 464 init1: 183 opt: 615 Z-score: 523.3 bits: 105.6 E(85289): 2.1e-22
Smith-Waterman score: 615; 33.3% identity (64.3% similar) in 339 aa overlap (1-329:6-333)
10 20 30 40 50
pF1KE4 MARAMAAAWPLLLVALLVLSWPPPGTGDVVVQAPTQVPGFLGDSVTLPCYLQVPN
.: : . : : :: . .. ::. . :::. .. ::.: .:.: : . :
NP_976 MARMGLAGAAGRWWGL---ALGLTAFFLPGVHSQVVQVNDSMYGFIGTDVVLHCSFANP-
10 20 30 40 50
60 70 80 90 100 110
pF1KE4 MEVTHVSQLTWAR--HGESGSMAVFHQTQGPSY--SESKRLEFVAARLGAELRNASLRMF
. ....:.:: . .: . ..:... ..: : .:.:: : . ....:.
NP_976 LPSVKITQVTWQKSTNGSKQNVAIYNPSMGVSVLAPYRERVEF----LRPSFTDGTIRLS
60 70 80 90 100 110
120 130 140 150 160
pF1KE4 GLRVEDEGNYTCLFVTFPQGSRSVDIWLRVLAKPQNTAEVQKVQLTG-----EPVPMARC
:..:::: : : :.::: :.: .. : :.::: : : .. : . . : .: :
NP_976 RLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVLVATC
120 130 140 150 160 170
170 180 190 200 210 220
pF1KE4 VSTGGRPPAQITWHSDLGGMPNTSQVPGFLSGTVTVTSLWILVPSSQVDGKNVTCKVEHE
.:..:.::. ..:.. : : . ... . .::::: : . :::: .. ....: :...
NP_976 TSANGKPPSVVSWETRLKGEAEYQEIRNP-NGTVTVISRYRLVPSREAHQQSLACIVNYH
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE4 SFEKPQLLTVNLTVYYPPEVSISGYDNNWYLGQNEATLTCDARSNPEPTGYNWSTTMGPL
. . ::.: : : :::.: :.:.:::: . .. ::: : .:: : :.:.: : :
NP_976 MDRFKESLTLN--VQYEPEVTIEGFDGNWYLQRMDVKLTCKADANPPATEYHWTTLNGSL
240 250 260 270 280
290 300 310 320 330 340
pF1KE4 PPFAVAQGAQLLIR-PVDKPINTTLICNVTNALGARQAELTVQVKEGPPSEHSGMSRNAI
: . ::. :... :.. . : ::..:: .:.:.... :..
NP_976 PKGVEAQNRTLFFKGPINYSLAGTYICEATNPIGTRSGQVEVNITAFCQLIYPGKGRTRA
290 300 310 320 330 340
350 360 370 380 390 400
pF1KE4 IFLVLGILVFLILLGIGIYFYWSKCSREVLWHCHLCPSSTEHASASANGHVSYSAVSREN
NP_976 RMF
350
417 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 17:18:23 2016 done: Mon Nov 7 17:18:25 2016
Total Scan time: 9.320 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]