Result of FASTA (omim) for
pFN21AE4381
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE4381, 401 aa
1>>>pF1KE4381 401 - 401 aa - 401 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.2178+/-0.000413; mu= 17.2848+/- 0.026
mean_var=64.9357+/-13.367, 0's: 0 Z-trim(110.4): 61 B-trim: 510 in 1/52
Lambda= 0.159160
statistics sampled from 18663 (18724) to 18663 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.585), E-opt: 0.2 (0.22), width: 16
Scan time: 7.090
The best scores are: opt bits E(85289)
NP_751891 (OMIM: 601141) voltage-gated potassium c ( 401) 2629 612.8 4.5e-175
NP_003462 (OMIM: 601141) voltage-gated potassium c ( 408) 2236 522.6 6.7e-148
NP_751892 (OMIM: 601141) voltage-gated potassium c ( 419) 2214 517.6 2.3e-146
XP_016862660 (OMIM: 601141) PREDICTED: voltage-gat ( 337) 2171 507.6 1.8e-143
XP_011511417 (OMIM: 601141) PREDICTED: voltage-gat ( 337) 2171 507.6 1.8e-143
XP_016858109 (OMIM: 601142) PREDICTED: voltage-gat ( 400) 2006 469.8 5.2e-132
XP_016858108 (OMIM: 601142) PREDICTED: voltage-gat ( 420) 2006 469.8 5.4e-132
XP_016858107 (OMIM: 601142) PREDICTED: voltage-gat ( 420) 2006 469.8 5.4e-132
XP_011511418 (OMIM: 601141) PREDICTED: voltage-gat ( 334) 1979 463.5 3.3e-130
XP_016862662 (OMIM: 601141) PREDICTED: voltage-gat ( 295) 1951 457.1 2.6e-128
XP_016862661 (OMIM: 601141) PREDICTED: voltage-gat ( 295) 1951 457.1 2.6e-128
XP_011511419 (OMIM: 601141) PREDICTED: voltage-gat ( 295) 1951 457.1 2.6e-128
NP_742128 (OMIM: 601142) voltage-gated potassium c ( 353) 1946 456.0 6.6e-128
XP_005263571 (OMIM: 601142) PREDICTED: voltage-gat ( 353) 1946 456.0 6.6e-128
NP_001186790 (OMIM: 601142) voltage-gated potassiu ( 367) 1940 454.6 1.8e-127
NP_001186789 (OMIM: 601142) voltage-gated potassiu ( 367) 1940 454.6 1.8e-127
NP_003627 (OMIM: 601142) voltage-gated potassium c ( 367) 1940 454.6 1.8e-127
NP_004723 (OMIM: 604111) voltage-gated potassium c ( 404) 1817 426.4 6.1e-119
XP_011540624 (OMIM: 601142) PREDICTED: voltage-gat ( 395) 1798 422.0 1.2e-117
XP_011540623 (OMIM: 601142) PREDICTED: voltage-gat ( 395) 1798 422.0 1.2e-117
NP_001186792 (OMIM: 601142) voltage-gated potassiu ( 300) 1734 407.3 2.6e-113
XP_016880793 (OMIM: 604111) PREDICTED: voltage-gat ( 384) 1459 344.2 3.3e-94
XP_011522370 (OMIM: 604111) PREDICTED: voltage-gat ( 411) 1453 342.8 9e-94
NP_001295151 (OMIM: 601141) voltage-gated potassiu ( 372) 1354 320.1 5.8e-87
NP_001295146 (OMIM: 601141) voltage-gated potassiu ( 390) 1354 320.1 6e-87
NP_001186791 (OMIM: 601142) voltage-gated potassiu ( 415) 1163 276.2 1e-73
XP_016858110 (OMIM: 601142) PREDICTED: voltage-gat ( 435) 1163 276.2 1e-73
XP_016880795 (OMIM: 604111) PREDICTED: voltage-gat ( 326) 997 238.0 2.4e-62
XP_016862663 (OMIM: 601141) PREDICTED: voltage-gat ( 233) 884 212.0 1.2e-54
XP_016880794 (OMIM: 604111) PREDICTED: voltage-gat ( 382) 751 181.6 2.8e-45
NP_003680 (OMIM: 603418) aflatoxin B1 aldehyde red ( 359) 264 69.8 1.2e-11
NP_036199 (OMIM: 608477) aflatoxin B1 aldehyde red ( 331) 261 69.0 1.9e-11
XP_011539348 (OMIM: 608477) PREDICTED: aflatoxin B ( 375) 261 69.1 2.1e-11
XP_016856203 (OMIM: 608477) PREDICTED: aflatoxin B ( 304) 217 58.9 1.9e-08
NP_001307908 (OMIM: 603418) aflatoxin B1 aldehyde ( 324) 176 49.5 1.4e-05
NP_064695 (OMIM: 604707) aldo-keto reductase famil ( 316) 142 41.7 0.003
NP_001619 (OMIM: 103880) aldose reductase isoform ( 316) 139 41.0 0.0048
NP_995317 (OMIM: 600450,614279) aldo-keto reductas ( 323) 138 40.8 0.0058
NP_001345 (OMIM: 600450,614279) aldo-keto reductas ( 323) 138 40.8 0.0058
>>NP_751891 (OMIM: 601141) voltage-gated potassium chann (401 aa)
initn: 2629 init1: 2629 opt: 2629 Z-score: 3264.0 bits: 612.8 E(85289): 4.5e-175
Smith-Waterman score: 2629; 100.0% identity (100.0% similar) in 401 aa overlap (1-401:1-401)
10 20 30 40 50 60
pF1KE4 MQVSIACTEHNLKSRNGEDRLLSKQSSTAPNVVNAARAKFRTVAIIARSLGTFTPQHHIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_751 MQVSIACTEHNLKSRNGEDRLLSKQSSTAPNVVNAARAKFRTVAIIARSLGTFTPQHHIS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 LKESTAKQTGMKYRNLGKSGLRVSCLGLGTWVTFGGQISDEVAERLMTIAYESGVNLFDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_751 LKESTAKQTGMKYRNLGKSGLRVSCLGLGTWVTFGGQISDEVAERLMTIAYESGVNLFDT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 AEVYAAGKAEVILGSIIKKKGWRRSSLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_751 AEVYAAGKAEVILGSIIKKKGWRRSSLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 LQLEYVDVVFANRPDSNTPMEEIVRAMTHVINQGMAMYWGTSRWSAMEIMEAYSVARQFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_751 LQLEYVDVVFANRPDSNTPMEEIVRAMTHVINQGMAMYWGTSRWSAMEIMEAYSVARQFN
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 MIPPVCEQAEYHLFQREKVEVQLPELYHKIGVGAMTWSPLACGIISGKYGNGVPESSRAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_751 MIPPVCEQAEYHLFQREKVEVQLPELYHKIGVGAMTWSPLACGIISGKYGNGVPESSRAS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 LKCYQWLKERIVSEEGRKQQNKLKDLSPIAERLGCTLPQLAVAWCLRNEGVSSVLLGSST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_751 LKCYQWLKERIVSEEGRKQQNKLKDLSPIAERLGCTLPQLAVAWCLRNEGVSSVLLGSST
310 320 330 340 350 360
370 380 390 400
pF1KE4 PEQLIENLGAIQVLPKMTSHVVNEIDNILRNKPYSKKDYRS
:::::::::::::::::::::::::::::::::::::::::
NP_751 PEQLIENLGAIQVLPKMTSHVVNEIDNILRNKPYSKKDYRS
370 380 390 400
>>NP_003462 (OMIM: 601141) voltage-gated potassium chann (408 aa)
initn: 2235 init1: 2235 opt: 2236 Z-score: 2776.2 bits: 522.6 E(85289): 6.7e-148
Smith-Waterman score: 2236; 97.1% identity (98.0% similar) in 349 aa overlap (53-401:60-408)
30 40 50 60 70 80
pF1KE4 SKQSSTAPNVVNAARAKFRTVAIIARSLGTFTPQHHISLKESTAKQTGMKYRNLGKSGLR
: : :::.:.: .::: ::::::::::
NP_003 WHLAVTKTQPQAACKPVRPSGAAEQKYVEKFLRVHGISLQETTRAETGMAYRNLGKSGLR
30 40 50 60 70 80
90 100 110 120 130 140
pF1KE4 VSCLGLGTWVTFGGQISDEVAERLMTIAYESGVNLFDTAEVYAAGKAEVILGSIIKKKGW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 VSCLGLGTWVTFGGQISDEVAERLMTIAYESGVNLFDTAEVYAAGKAEVILGSIIKKKGW
90 100 110 120 130 140
150 160 170 180 190 200
pF1KE4 RRSSLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQRLQLEYVDVVFANRPDSNTPMEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 RRSSLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQRLQLEYVDVVFANRPDSNTPMEE
150 160 170 180 190 200
210 220 230 240 250 260
pF1KE4 IVRAMTHVINQGMAMYWGTSRWSAMEIMEAYSVARQFNMIPPVCEQAEYHLFQREKVEVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 IVRAMTHVINQGMAMYWGTSRWSAMEIMEAYSVARQFNMIPPVCEQAEYHLFQREKVEVQ
210 220 230 240 250 260
270 280 290 300 310 320
pF1KE4 LPELYHKIGVGAMTWSPLACGIISGKYGNGVPESSRASLKCYQWLKERIVSEEGRKQQNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LPELYHKIGVGAMTWSPLACGIISGKYGNGVPESSRASLKCYQWLKERIVSEEGRKQQNK
270 280 290 300 310 320
330 340 350 360 370 380
pF1KE4 LKDLSPIAERLGCTLPQLAVAWCLRNEGVSSVLLGSSTPEQLIENLGAIQVLPKMTSHVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LKDLSPIAERLGCTLPQLAVAWCLRNEGVSSVLLGSSTPEQLIENLGAIQVLPKMTSHVV
330 340 350 360 370 380
390 400
pF1KE4 NEIDNILRNKPYSKKDYRS
:::::::::::::::::::
NP_003 NEIDNILRNKPYSKKDYRS
390 400
>>NP_751892 (OMIM: 601141) voltage-gated potassium chann (419 aa)
initn: 2200 init1: 2200 opt: 2214 Z-score: 2748.8 bits: 517.6 E(85289): 2.3e-146
Smith-Waterman score: 2214; 89.7% identity (94.5% similar) in 380 aa overlap (23-401:42-419)
10 20 30 40 50
pF1KE4 MQVSIACTEHNLKSRNGEDRLLSKQSSTAPNVVNAARAKFRTVAIIAR-SLG
.:.:: .:. . :: : .:.. . ..
NP_751 QISEENTKLRRQSGFSVAGKDKSPKKASENAKDSSLSPSGESQLRA--RQLALLREVEMN
20 30 40 50 60
60 70 80 90 100 110
pF1KE4 TFTPQHHISLKESTAKQTGMKYRNLGKSGLRVSCLGLGTWVTFGGQISDEVAERLMTIAY
. .: ...:. ::: .::::::::::::::::::::::::::::::::::::::
NP_751 WYLKLCDLSSEHTTVCTTGMPHRNLGKSGLRVSCLGLGTWVTFGGQISDEVAERLMTIAY
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE4 ESGVNLFDTAEVYAAGKAEVILGSIIKKKGWRRSSLVITTKLYWGGKAETERGLSRKHII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_751 ESGVNLFDTAEVYAAGKAEVILGSIIKKKGWRRSSLVITTKLYWGGKAETERGLSRKHII
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE4 EGLKGSLQRLQLEYVDVVFANRPDSNTPMEEIVRAMTHVINQGMAMYWGTSRWSAMEIME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_751 EGLKGSLQRLQLEYVDVVFANRPDSNTPMEEIVRAMTHVINQGMAMYWGTSRWSAMEIME
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE4 AYSVARQFNMIPPVCEQAEYHLFQREKVEVQLPELYHKIGVGAMTWSPLACGIISGKYGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_751 AYSVARQFNMIPPVCEQAEYHLFQREKVEVQLPELYHKIGVGAMTWSPLACGIISGKYGN
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE4 GVPESSRASLKCYQWLKERIVSEEGRKQQNKLKDLSPIAERLGCTLPQLAVAWCLRNEGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_751 GVPESSRASLKCYQWLKERIVSEEGRKQQNKLKDLSPIAERLGCTLPQLAVAWCLRNEGV
310 320 330 340 350 360
360 370 380 390 400
pF1KE4 SSVLLGSSTPEQLIENLGAIQVLPKMTSHVVNEIDNILRNKPYSKKDYRS
::::::::::::::::::::::::::::::::::::::::::::::::::
NP_751 SSVLLGSSTPEQLIENLGAIQVLPKMTSHVVNEIDNILRNKPYSKKDYRS
370 380 390 400 410
>>XP_016862660 (OMIM: 601141) PREDICTED: voltage-gated p (337 aa)
initn: 2171 init1: 2171 opt: 2171 Z-score: 2696.8 bits: 507.6 E(85289): 1.8e-143
Smith-Waterman score: 2171; 100.0% identity (100.0% similar) in 328 aa overlap (74-401:10-337)
50 60 70 80 90 100
pF1KE4 AIIARSLGTFTPQHHISLKESTAKQTGMKYRNLGKSGLRVSCLGLGTWVTFGGQISDEVA
::::::::::::::::::::::::::::::
XP_016 MWLSSKAMLRNLGKSGLRVSCLGLGTWVTFGGQISDEVA
10 20 30
110 120 130 140 150 160
pF1KE4 ERLMTIAYESGVNLFDTAEVYAAGKAEVILGSIIKKKGWRRSSLVITTKLYWGGKAETER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ERLMTIAYESGVNLFDTAEVYAAGKAEVILGSIIKKKGWRRSSLVITTKLYWGGKAETER
40 50 60 70 80 90
170 180 190 200 210 220
pF1KE4 GLSRKHIIEGLKGSLQRLQLEYVDVVFANRPDSNTPMEEIVRAMTHVINQGMAMYWGTSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLSRKHIIEGLKGSLQRLQLEYVDVVFANRPDSNTPMEEIVRAMTHVINQGMAMYWGTSR
100 110 120 130 140 150
230 240 250 260 270 280
pF1KE4 WSAMEIMEAYSVARQFNMIPPVCEQAEYHLFQREKVEVQLPELYHKIGVGAMTWSPLACG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WSAMEIMEAYSVARQFNMIPPVCEQAEYHLFQREKVEVQLPELYHKIGVGAMTWSPLACG
160 170 180 190 200 210
290 300 310 320 330 340
pF1KE4 IISGKYGNGVPESSRASLKCYQWLKERIVSEEGRKQQNKLKDLSPIAERLGCTLPQLAVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IISGKYGNGVPESSRASLKCYQWLKERIVSEEGRKQQNKLKDLSPIAERLGCTLPQLAVA
220 230 240 250 260 270
350 360 370 380 390 400
pF1KE4 WCLRNEGVSSVLLGSSTPEQLIENLGAIQVLPKMTSHVVNEIDNILRNKPYSKKDYRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WCLRNEGVSSVLLGSSTPEQLIENLGAIQVLPKMTSHVVNEIDNILRNKPYSKKDYRS
280 290 300 310 320 330
>>XP_011511417 (OMIM: 601141) PREDICTED: voltage-gated p (337 aa)
initn: 2171 init1: 2171 opt: 2171 Z-score: 2696.8 bits: 507.6 E(85289): 1.8e-143
Smith-Waterman score: 2171; 100.0% identity (100.0% similar) in 328 aa overlap (74-401:10-337)
50 60 70 80 90 100
pF1KE4 AIIARSLGTFTPQHHISLKESTAKQTGMKYRNLGKSGLRVSCLGLGTWVTFGGQISDEVA
::::::::::::::::::::::::::::::
XP_011 MIINEANVMRNLGKSGLRVSCLGLGTWVTFGGQISDEVA
10 20 30
110 120 130 140 150 160
pF1KE4 ERLMTIAYESGVNLFDTAEVYAAGKAEVILGSIIKKKGWRRSSLVITTKLYWGGKAETER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ERLMTIAYESGVNLFDTAEVYAAGKAEVILGSIIKKKGWRRSSLVITTKLYWGGKAETER
40 50 60 70 80 90
170 180 190 200 210 220
pF1KE4 GLSRKHIIEGLKGSLQRLQLEYVDVVFANRPDSNTPMEEIVRAMTHVINQGMAMYWGTSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLSRKHIIEGLKGSLQRLQLEYVDVVFANRPDSNTPMEEIVRAMTHVINQGMAMYWGTSR
100 110 120 130 140 150
230 240 250 260 270 280
pF1KE4 WSAMEIMEAYSVARQFNMIPPVCEQAEYHLFQREKVEVQLPELYHKIGVGAMTWSPLACG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WSAMEIMEAYSVARQFNMIPPVCEQAEYHLFQREKVEVQLPELYHKIGVGAMTWSPLACG
160 170 180 190 200 210
290 300 310 320 330 340
pF1KE4 IISGKYGNGVPESSRASLKCYQWLKERIVSEEGRKQQNKLKDLSPIAERLGCTLPQLAVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IISGKYGNGVPESSRASLKCYQWLKERIVSEEGRKQQNKLKDLSPIAERLGCTLPQLAVA
220 230 240 250 260 270
350 360 370 380 390 400
pF1KE4 WCLRNEGVSSVLLGSSTPEQLIENLGAIQVLPKMTSHVVNEIDNILRNKPYSKKDYRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WCLRNEGVSSVLLGSSTPEQLIENLGAIQVLPKMTSHVVNEIDNILRNKPYSKKDYRS
280 290 300 310 320 330
>>XP_016858109 (OMIM: 601142) PREDICTED: voltage-gated p (400 aa)
initn: 2005 init1: 2005 opt: 2006 Z-score: 2490.9 bits: 469.8 E(85289): 5.2e-132
Smith-Waterman score: 2006; 80.3% identity (93.4% similar) in 365 aa overlap (39-401:36-400)
10 20 30 40 50 60
pF1KE4 EHNLKSRNGEDRLLSKQSSTAPNVVNAARAKFRTV--AIIARSLGTFTPQHHISLKESTA
..: : : ::.. .: .: .:: ::
XP_016 YSESLRSVSSRCHSEWALHPVRQTDTLELQRLREVRAAAQARNMESFLRMHGLSLDGCTA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 KQTGMKYRNLGKSGLRVSCLGLGTWVTFGGQISDEVAERLMTIAYESGVNLFDTAEVYAA
..::::::::::::::::::::::::::::::.::.::.:::.::..:.:::::::::::
XP_016 QRTGMKYRNLGKSGLRVSCLGLGTWVTFGGQITDEMAEQLMTLAYDNGINLFDTAEVYAA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 GKAEVILGSIIKKKGWRRSSLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQRLQLEYV
:::::.::.:::::::::::::::::..:::::::::::::::::::::.::.:::::::
XP_016 GKAEVVLGNIIKKKGWRRSSLVITTKIFWGGKAETERGLSRKHIIEGLKASLERLQLEYV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 DVVFANRPDSNTPMEEIVRAMTHVINQGMAMYWGTSRWSAMEIMEAYSVARQFNMIPPVC
::::::::: :::::: ::::::::::::::::::::::.::::::::::::::. ::.:
XP_016 DVVFANRPDPNTPMEETVRAMTHVINQGMAMYWGTSRWSSMEIMEAYSVARQFNLTPPIC
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 EQAEYHLFQREKVEVQLPELYHKIGVGAMTWSPLACGIISGKYGNGVPESSRASLKCYQW
::::::.:::::::::::::.:::::::::::::::::.:::: .:.: :::::: :::
XP_016 EQAEYHMFQREKVEVQLPELFHKIGVGAMTWSPLACGIVSGKYDSGIPPYSRASLKGYQW
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 LKERIVSEEGRKQQNKLKDLSPIAERLGCTLPQLAVAWCLRNEGVSSVLLGSSTPEQLIE
::..:.:::::.:: :::.:. :::::::::::::.:::::::::::::::.:. .::.:
XP_016 LKDKILSEEGRRQQAKLKELQAIAERLGCTLPQLAIAWCLRNEGVSSVLLGASNADQLME
310 320 330 340 350 360
370 380 390 400
pF1KE4 NLGAIQVLPKMTSHVVNEIDNILRNKPYSKKDYRS
:.::::::::..: ...:::.:: :::::::::::
XP_016 NIGAIQVLPKLSSSIIHEIDSILGNKPYSKKDYRS
370 380 390 400
>>XP_016858108 (OMIM: 601142) PREDICTED: voltage-gated p (420 aa)
initn: 2005 init1: 2005 opt: 2006 Z-score: 2490.6 bits: 469.8 E(85289): 5.4e-132
Smith-Waterman score: 2006; 80.3% identity (93.4% similar) in 365 aa overlap (39-401:56-420)
10 20 30 40 50 60
pF1KE4 EHNLKSRNGEDRLLSKQSSTAPNVVNAARAKFRTV--AIIARSLGTFTPQHHISLKESTA
..: : : ::.. .: .: .:: ::
XP_016 YSESLRSVSSRCHSEWALHPVRQTDTLELQRLREVRAAAQARNMESFLRMHGLSLDGCTA
30 40 50 60 70 80
70 80 90 100 110 120
pF1KE4 KQTGMKYRNLGKSGLRVSCLGLGTWVTFGGQISDEVAERLMTIAYESGVNLFDTAEVYAA
..::::::::::::::::::::::::::::::.::.::.:::.::..:.:::::::::::
XP_016 QRTGMKYRNLGKSGLRVSCLGLGTWVTFGGQITDEMAEQLMTLAYDNGINLFDTAEVYAA
90 100 110 120 130 140
130 140 150 160 170 180
pF1KE4 GKAEVILGSIIKKKGWRRSSLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQRLQLEYV
:::::.::.:::::::::::::::::..:::::::::::::::::::::.::.:::::::
XP_016 GKAEVVLGNIIKKKGWRRSSLVITTKIFWGGKAETERGLSRKHIIEGLKASLERLQLEYV
150 160 170 180 190 200
190 200 210 220 230 240
pF1KE4 DVVFANRPDSNTPMEEIVRAMTHVINQGMAMYWGTSRWSAMEIMEAYSVARQFNMIPPVC
::::::::: :::::: ::::::::::::::::::::::.::::::::::::::. ::.:
XP_016 DVVFANRPDPNTPMEETVRAMTHVINQGMAMYWGTSRWSSMEIMEAYSVARQFNLTPPIC
210 220 230 240 250 260
250 260 270 280 290 300
pF1KE4 EQAEYHLFQREKVEVQLPELYHKIGVGAMTWSPLACGIISGKYGNGVPESSRASLKCYQW
::::::.:::::::::::::.:::::::::::::::::.:::: .:.: :::::: :::
XP_016 EQAEYHMFQREKVEVQLPELFHKIGVGAMTWSPLACGIVSGKYDSGIPPYSRASLKGYQW
270 280 290 300 310 320
310 320 330 340 350 360
pF1KE4 LKERIVSEEGRKQQNKLKDLSPIAERLGCTLPQLAVAWCLRNEGVSSVLLGSSTPEQLIE
::..:.:::::.:: :::.:. :::::::::::::.:::::::::::::::.:. .::.:
XP_016 LKDKILSEEGRRQQAKLKELQAIAERLGCTLPQLAIAWCLRNEGVSSVLLGASNADQLME
330 340 350 360 370 380
370 380 390 400
pF1KE4 NLGAIQVLPKMTSHVVNEIDNILRNKPYSKKDYRS
:.::::::::..: ...:::.:: :::::::::::
XP_016 NIGAIQVLPKLSSSIIHEIDSILGNKPYSKKDYRS
390 400 410 420
>>XP_016858107 (OMIM: 601142) PREDICTED: voltage-gated p (420 aa)
initn: 2005 init1: 2005 opt: 2006 Z-score: 2490.6 bits: 469.8 E(85289): 5.4e-132
Smith-Waterman score: 2006; 80.3% identity (93.4% similar) in 365 aa overlap (39-401:56-420)
10 20 30 40 50 60
pF1KE4 EHNLKSRNGEDRLLSKQSSTAPNVVNAARAKFRTV--AIIARSLGTFTPQHHISLKESTA
..: : : ::.. .: .: .:: ::
XP_016 YSESLRSVSSRCHSEWALHPVRQTDTLELQRLREVRAAAQARNMESFLRMHGLSLDGCTA
30 40 50 60 70 80
70 80 90 100 110 120
pF1KE4 KQTGMKYRNLGKSGLRVSCLGLGTWVTFGGQISDEVAERLMTIAYESGVNLFDTAEVYAA
..::::::::::::::::::::::::::::::.::.::.:::.::..:.:::::::::::
XP_016 QRTGMKYRNLGKSGLRVSCLGLGTWVTFGGQITDEMAEQLMTLAYDNGINLFDTAEVYAA
90 100 110 120 130 140
130 140 150 160 170 180
pF1KE4 GKAEVILGSIIKKKGWRRSSLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQRLQLEYV
:::::.::.:::::::::::::::::..:::::::::::::::::::::.::.:::::::
XP_016 GKAEVVLGNIIKKKGWRRSSLVITTKIFWGGKAETERGLSRKHIIEGLKASLERLQLEYV
150 160 170 180 190 200
190 200 210 220 230 240
pF1KE4 DVVFANRPDSNTPMEEIVRAMTHVINQGMAMYWGTSRWSAMEIMEAYSVARQFNMIPPVC
::::::::: :::::: ::::::::::::::::::::::.::::::::::::::. ::.:
XP_016 DVVFANRPDPNTPMEETVRAMTHVINQGMAMYWGTSRWSSMEIMEAYSVARQFNLTPPIC
210 220 230 240 250 260
250 260 270 280 290 300
pF1KE4 EQAEYHLFQREKVEVQLPELYHKIGVGAMTWSPLACGIISGKYGNGVPESSRASLKCYQW
::::::.:::::::::::::.:::::::::::::::::.:::: .:.: :::::: :::
XP_016 EQAEYHMFQREKVEVQLPELFHKIGVGAMTWSPLACGIVSGKYDSGIPPYSRASLKGYQW
270 280 290 300 310 320
310 320 330 340 350 360
pF1KE4 LKERIVSEEGRKQQNKLKDLSPIAERLGCTLPQLAVAWCLRNEGVSSVLLGSSTPEQLIE
::..:.:::::.:: :::.:. :::::::::::::.:::::::::::::::.:. .::.:
XP_016 LKDKILSEEGRRQQAKLKELQAIAERLGCTLPQLAIAWCLRNEGVSSVLLGASNADQLME
330 340 350 360 370 380
370 380 390 400
pF1KE4 NLGAIQVLPKMTSHVVNEIDNILRNKPYSKKDYRS
:.::::::::..: ...:::.:: :::::::::::
XP_016 NIGAIQVLPKLSSSIIHEIDSILGNKPYSKKDYRS
390 400 410 420
>>XP_011511418 (OMIM: 601141) PREDICTED: voltage-gated p (334 aa)
initn: 1979 init1: 1979 opt: 1979 Z-score: 2458.6 bits: 463.5 E(85289): 3.3e-130
Smith-Waterman score: 1979; 100.0% identity (100.0% similar) in 300 aa overlap (102-401:35-334)
80 90 100 110 120 130
pF1KE4 KYRNLGKSGLRVSCLGLGTWVTFGGQISDEVAERLMTIAYESGVNLFDTAEVYAAGKAEV
::::::::::::::::::::::::::::::
XP_011 EIPEQNQPHFANQEAKFTERSDDLPTFIFLVAERLMTIAYESGVNLFDTAEVYAAGKAEV
10 20 30 40 50 60
140 150 160 170 180 190
pF1KE4 ILGSIIKKKGWRRSSLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQRLQLEYVDVVFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ILGSIIKKKGWRRSSLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQRLQLEYVDVVFA
70 80 90 100 110 120
200 210 220 230 240 250
pF1KE4 NRPDSNTPMEEIVRAMTHVINQGMAMYWGTSRWSAMEIMEAYSVARQFNMIPPVCEQAEY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NRPDSNTPMEEIVRAMTHVINQGMAMYWGTSRWSAMEIMEAYSVARQFNMIPPVCEQAEY
130 140 150 160 170 180
260 270 280 290 300 310
pF1KE4 HLFQREKVEVQLPELYHKIGVGAMTWSPLACGIISGKYGNGVPESSRASLKCYQWLKERI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HLFQREKVEVQLPELYHKIGVGAMTWSPLACGIISGKYGNGVPESSRASLKCYQWLKERI
190 200 210 220 230 240
320 330 340 350 360 370
pF1KE4 VSEEGRKQQNKLKDLSPIAERLGCTLPQLAVAWCLRNEGVSSVLLGSSTPEQLIENLGAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VSEEGRKQQNKLKDLSPIAERLGCTLPQLAVAWCLRNEGVSSVLLGSSTPEQLIENLGAI
250 260 270 280 290 300
380 390 400
pF1KE4 QVLPKMTSHVVNEIDNILRNKPYSKKDYRS
::::::::::::::::::::::::::::::
XP_011 QVLPKMTSHVVNEIDNILRNKPYSKKDYRS
310 320 330
>>XP_016862662 (OMIM: 601141) PREDICTED: voltage-gated p (295 aa)
initn: 1951 init1: 1951 opt: 1951 Z-score: 2424.7 bits: 457.1 E(85289): 2.6e-128
Smith-Waterman score: 1951; 100.0% identity (100.0% similar) in 295 aa overlap (107-401:1-295)
80 90 100 110 120 130
pF1KE4 GKSGLRVSCLGLGTWVTFGGQISDEVAERLMTIAYESGVNLFDTAEVYAAGKAEVILGSI
::::::::::::::::::::::::::::::
XP_016 MTIAYESGVNLFDTAEVYAAGKAEVILGSI
10 20 30
140 150 160 170 180 190
pF1KE4 IKKKGWRRSSLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQRLQLEYVDVVFANRPDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IKKKGWRRSSLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQRLQLEYVDVVFANRPDS
40 50 60 70 80 90
200 210 220 230 240 250
pF1KE4 NTPMEEIVRAMTHVINQGMAMYWGTSRWSAMEIMEAYSVARQFNMIPPVCEQAEYHLFQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NTPMEEIVRAMTHVINQGMAMYWGTSRWSAMEIMEAYSVARQFNMIPPVCEQAEYHLFQR
100 110 120 130 140 150
260 270 280 290 300 310
pF1KE4 EKVEVQLPELYHKIGVGAMTWSPLACGIISGKYGNGVPESSRASLKCYQWLKERIVSEEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EKVEVQLPELYHKIGVGAMTWSPLACGIISGKYGNGVPESSRASLKCYQWLKERIVSEEG
160 170 180 190 200 210
320 330 340 350 360 370
pF1KE4 RKQQNKLKDLSPIAERLGCTLPQLAVAWCLRNEGVSSVLLGSSTPEQLIENLGAIQVLPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RKQQNKLKDLSPIAERLGCTLPQLAVAWCLRNEGVSSVLLGSSTPEQLIENLGAIQVLPK
220 230 240 250 260 270
380 390 400
pF1KE4 MTSHVVNEIDNILRNKPYSKKDYRS
:::::::::::::::::::::::::
XP_016 MTSHVVNEIDNILRNKPYSKKDYRS
280 290
401 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 22:59:15 2016 done: Sat Nov 5 22:59:16 2016
Total Scan time: 7.090 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]