Result of FASTA (omim) for
pFN21AE4377
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE4377, 399 aa
1>>>pF1KE4377 399 - 399 aa - 399 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.3283+/-0.000404; mu= 16.3134+/- 0.025
mean_var=61.6722+/-12.817, 0's: 0 Z-trim(111.0): 39 B-trim: 797 in 1/52
Lambda= 0.163316
statistics sampled from 19442 (19481) to 19442 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.598), E-opt: 0.2 (0.228), width: 16
Scan time: 6.060
The best scores are: opt bits E(85289)
NP_001121077 (OMIM: 278000,613497) lysosomal acid ( 399) 2759 658.9 5.9e-189
NP_000226 (OMIM: 278000,613497) lysosomal acid lip ( 399) 2759 658.9 5.9e-189
NP_001275908 (OMIM: 278000,613497) lysosomal acid ( 283) 1973 473.7 2.5e-133
NP_001121687 (OMIM: 613923) lipase member M precur ( 423) 1678 404.3 2.9e-112
XP_011538050 (OMIM: 613923) PREDICTED: lipase memb ( 430) 1654 398.6 1.5e-110
NP_001185758 (OMIM: 601980) gastric triacylglycero ( 408) 1623 391.3 2.3e-108
XP_011538613 (OMIM: 601980) PREDICTED: gastric tri ( 398) 1619 390.3 4.2e-108
NP_004181 (OMIM: 601980) gastric triacylglycerol l ( 398) 1619 390.3 4.2e-108
XP_011538377 (OMIM: 613922) PREDICTED: lipase memb ( 408) 1574 379.7 6.7e-105
XP_011538375 (OMIM: 613922) PREDICTED: lipase memb ( 419) 1574 379.7 6.9e-105
XP_011538379 (OMIM: 613922) PREDICTED: lipase memb ( 399) 1573 379.5 7.8e-105
NP_001073987 (OMIM: 613922) lipase member K precur ( 399) 1573 379.5 7.8e-105
NP_001095939 (OMIM: 613924,613943) lipase member N ( 398) 1492 360.4 4.3e-99
XP_011538386 (OMIM: 613924,613943) PREDICTED: lipa ( 398) 1492 360.4 4.3e-99
XP_011538385 (OMIM: 613924,613943) PREDICTED: lipa ( 398) 1492 360.4 4.3e-99
XP_005270106 (OMIM: 613924,613943) PREDICTED: lipa ( 398) 1492 360.4 4.3e-99
XP_006717698 (OMIM: 613921) PREDICTED: lipase memb ( 366) 1400 338.7 1.3e-92
NP_001010939 (OMIM: 613921) lipase member J [Homo ( 366) 1400 338.7 1.3e-92
XP_011537617 (OMIM: 613921) PREDICTED: lipase memb ( 366) 1400 338.7 1.3e-92
XP_011537616 (OMIM: 613921) PREDICTED: lipase memb ( 366) 1400 338.7 1.3e-92
XP_011538053 (OMIM: 613923) PREDICTED: lipase memb ( 302) 1253 304.1 3e-82
NP_001185757 (OMIM: 601980) gastric triacylglycero ( 365) 1225 297.5 3.5e-80
NP_001185759 (OMIM: 601980) gastric triacylglycero ( 375) 1225 297.5 3.5e-80
XP_016872037 (OMIM: 613922) PREDICTED: lipase memb ( 358) 1220 296.3 7.7e-80
XP_016872034 (OMIM: 613922) PREDICTED: lipase memb ( 395) 1216 295.4 1.6e-79
XP_016872035 (OMIM: 613922) PREDICTED: lipase memb ( 386) 1209 293.7 5e-79
XP_016871229 (OMIM: 613921) PREDICTED: lipase memb ( 315) 1199 291.3 2.1e-78
XP_011538384 (OMIM: 613922) PREDICTED: lipase memb ( 265) 1027 250.8 2.9e-66
XP_011538387 (OMIM: 613924,613943) PREDICTED: lipa ( 374) 1022 249.7 8.9e-66
XP_011538388 (OMIM: 613924,613943) PREDICTED: lipa ( 350) 1013 247.5 3.6e-65
XP_011538055 (OMIM: 613923) PREDICTED: lipase memb ( 238) 959 234.7 1.8e-61
XP_016872036 (OMIM: 613922) PREDICTED: lipase memb ( 370) 917 224.9 2.5e-58
XP_016872038 (OMIM: 613924,613943) PREDICTED: lipa ( 244) 911 223.4 4.6e-58
XP_011538054 (OMIM: 613923) PREDICTED: lipase memb ( 240) 878 215.7 9.8e-56
XP_005269599 (OMIM: 613921) PREDICTED: lipase memb ( 253) 872 214.3 2.7e-55
XP_011537619 (OMIM: 613921) PREDICTED: lipase memb ( 317) 827 203.7 5.2e-52
XP_011537620 (OMIM: 613921) PREDICTED: lipase memb ( 225) 699 173.5 4.6e-43
XP_011537622 (OMIM: 613921) PREDICTED: lipase memb ( 184) 585 146.6 4.7e-35
XP_011537621 (OMIM: 613921) PREDICTED: lipase memb ( 184) 585 146.6 4.7e-35
>>NP_001121077 (OMIM: 278000,613497) lysosomal acid lipa (399 aa)
initn: 2759 init1: 2759 opt: 2759 Z-score: 3513.3 bits: 658.9 E(85289): 5.9e-189
Smith-Waterman score: 2759; 99.5% identity (99.7% similar) in 399 aa overlap (1-399:1-399)
10 20 30 40 50 60
pF1KE4 MKMRFLGLVVCLVLWPLHSEGSGGKLTALDPETNMNVSEIISYWGFPSEEYLVETEDGYI
::::::::::::::: ::::::::::::.:::::::::::::::::::::::::::::::
NP_001 MKMRFLGLVVCLVLWTLHSEGSGGKLTAVDPETNMNVSEIISYWGFPSEEYLVETEDGYI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 LCLNRIPHGRKNHSDKGPKPVVFLQHGLLADSSNWVTNLANSSLGFILADAGFDVWMGNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LCLNRIPHGRKNHSDKGPKPVVFLQHGLLADSSNWVTNLANSSLGFILADAGFDVWMGNS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 RGNTWSRKHKTLSVSQDEFWAFSYDEMAKYDLPASINFILNKTGQEQVYYVGHSQGTTIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RGNTWSRKHKTLSVSQDEFWAFSYDEMAKYDLPASINFILNKTGQEQVYYVGHSQGTTIG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 FIAFSQIPELAKRIKMFFALGPVASVAFCTSPMAKLGRLPDHLIKDLFGDKEFLPQSAFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FIAFSQIPELAKRIKMFFALGPVASVAFCTSPMAKLGRLPDHLIKDLFGDKEFLPQSAFL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 KWLGTHVCTHVILKELCGNLCFLLCGFNERNLNMSRVDVYTTHSPAGTSVQNMLHWSQAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KWLGTHVCTHVILKELCGNLCFLLCGFNERNLNMSRVDVYTTHSPAGTSVQNMLHWSQAV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 KFQKFQAFDWGSSAKNYFHYNQSYPPTYNVKDMLVPTAVWSGGHDWLADVYDVNILLTQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KFQKFQAFDWGSSAKNYFHYNQSYPPTYNVKDMLVPTAVWSGGHDWLADVYDVNILLTQI
310 320 330 340 350 360
370 380 390
pF1KE4 TNLVFHESIPEWEHLDFIWGLDAPWRLYNKIINLMRKYQ
:::::::::::::::::::::::::::::::::::::::
NP_001 TNLVFHESIPEWEHLDFIWGLDAPWRLYNKIINLMRKYQ
370 380 390
>>NP_000226 (OMIM: 278000,613497) lysosomal acid lipase/ (399 aa)
initn: 2759 init1: 2759 opt: 2759 Z-score: 3513.3 bits: 658.9 E(85289): 5.9e-189
Smith-Waterman score: 2759; 99.5% identity (99.7% similar) in 399 aa overlap (1-399:1-399)
10 20 30 40 50 60
pF1KE4 MKMRFLGLVVCLVLWPLHSEGSGGKLTALDPETNMNVSEIISYWGFPSEEYLVETEDGYI
::::::::::::::: ::::::::::::.:::::::::::::::::::::::::::::::
NP_000 MKMRFLGLVVCLVLWTLHSEGSGGKLTAVDPETNMNVSEIISYWGFPSEEYLVETEDGYI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 LCLNRIPHGRKNHSDKGPKPVVFLQHGLLADSSNWVTNLANSSLGFILADAGFDVWMGNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LCLNRIPHGRKNHSDKGPKPVVFLQHGLLADSSNWVTNLANSSLGFILADAGFDVWMGNS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 RGNTWSRKHKTLSVSQDEFWAFSYDEMAKYDLPASINFILNKTGQEQVYYVGHSQGTTIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 RGNTWSRKHKTLSVSQDEFWAFSYDEMAKYDLPASINFILNKTGQEQVYYVGHSQGTTIG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 FIAFSQIPELAKRIKMFFALGPVASVAFCTSPMAKLGRLPDHLIKDLFGDKEFLPQSAFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 FIAFSQIPELAKRIKMFFALGPVASVAFCTSPMAKLGRLPDHLIKDLFGDKEFLPQSAFL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 KWLGTHVCTHVILKELCGNLCFLLCGFNERNLNMSRVDVYTTHSPAGTSVQNMLHWSQAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 KWLGTHVCTHVILKELCGNLCFLLCGFNERNLNMSRVDVYTTHSPAGTSVQNMLHWSQAV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 KFQKFQAFDWGSSAKNYFHYNQSYPPTYNVKDMLVPTAVWSGGHDWLADVYDVNILLTQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 KFQKFQAFDWGSSAKNYFHYNQSYPPTYNVKDMLVPTAVWSGGHDWLADVYDVNILLTQI
310 320 330 340 350 360
370 380 390
pF1KE4 TNLVFHESIPEWEHLDFIWGLDAPWRLYNKIINLMRKYQ
:::::::::::::::::::::::::::::::::::::::
NP_000 TNLVFHESIPEWEHLDFIWGLDAPWRLYNKIINLMRKYQ
370 380 390
>>NP_001275908 (OMIM: 278000,613497) lysosomal acid lipa (283 aa)
initn: 1973 init1: 1973 opt: 1973 Z-score: 2514.8 bits: 473.7 E(85289): 2.5e-133
Smith-Waterman score: 1973; 100.0% identity (100.0% similar) in 283 aa overlap (117-399:1-283)
90 100 110 120 130 140
pF1KE4 GLLADSSNWVTNLANSSLGFILADAGFDVWMGNSRGNTWSRKHKTLSVSQDEFWAFSYDE
::::::::::::::::::::::::::::::
NP_001 MGNSRGNTWSRKHKTLSVSQDEFWAFSYDE
10 20 30
150 160 170 180 190 200
pF1KE4 MAKYDLPASINFILNKTGQEQVYYVGHSQGTTIGFIAFSQIPELAKRIKMFFALGPVASV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAKYDLPASINFILNKTGQEQVYYVGHSQGTTIGFIAFSQIPELAKRIKMFFALGPVASV
40 50 60 70 80 90
210 220 230 240 250 260
pF1KE4 AFCTSPMAKLGRLPDHLIKDLFGDKEFLPQSAFLKWLGTHVCTHVILKELCGNLCFLLCG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AFCTSPMAKLGRLPDHLIKDLFGDKEFLPQSAFLKWLGTHVCTHVILKELCGNLCFLLCG
100 110 120 130 140 150
270 280 290 300 310 320
pF1KE4 FNERNLNMSRVDVYTTHSPAGTSVQNMLHWSQAVKFQKFQAFDWGSSAKNYFHYNQSYPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FNERNLNMSRVDVYTTHSPAGTSVQNMLHWSQAVKFQKFQAFDWGSSAKNYFHYNQSYPP
160 170 180 190 200 210
330 340 350 360 370 380
pF1KE4 TYNVKDMLVPTAVWSGGHDWLADVYDVNILLTQITNLVFHESIPEWEHLDFIWGLDAPWR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TYNVKDMLVPTAVWSGGHDWLADVYDVNILLTQITNLVFHESIPEWEHLDFIWGLDAPWR
220 230 240 250 260 270
390
pF1KE4 LYNKIINLMRKYQ
:::::::::::::
NP_001 LYNKIINLMRKYQ
280
>>NP_001121687 (OMIM: 613923) lipase member M precursor (423 aa)
initn: 1668 init1: 1668 opt: 1678 Z-score: 2136.4 bits: 404.3 E(85289): 2.9e-112
Smith-Waterman score: 1678; 60.7% identity (82.9% similar) in 397 aa overlap (1-397:15-409)
10 20 30 40
pF1KE4 MKMRFLGLVVCLVLWPLHSEGSGGKLTALDPETNMNVSEIISYWGF
:.: .: ::. . ..: : :.:::. ::.::::.. :.
NP_001 MLETLSRQWIVSHRMEMWLLILVAYMFQRNVNSVHMPTK--AVDPEAFMNISEIIQHQGY
10 20 30 40 50
50 60 70 80 90 100
pF1KE4 PSEEYLVETEDGYILCLNRIPHGRKNHSDKGPKPVVFLQHGLLADSSNWVTNLANSSLGF
: ::: : ::::::: .::::.: . . : .:::.:::::.. .:::..:: :.::::
NP_001 PCEEYEVATEDGYILSVNRIPRGLVQPKKTGSRPVVLLQHGLVGGASNWISNLPNNSLGF
60 70 80 90 100 110
110 120 130 140 150 160
pF1KE4 ILADAGFDVWMGNSRGNTWSRKHKTLSVSQDEFWAFSYDEMAKYDLPASINFILNKTGQE
:::::::::::::::::.:::::::::..:::::::::::::..:::: :::::.:::::
NP_001 ILADAGFDVWMGNSRGNAWSRKHKTLSIDQDEFWAFSYDEMARFDLPAVINFILQKTGQE
120 130 140 150 160 170
170 180 190 200 210 220
pF1KE4 QVYYVGHSQGTTIGFIAFSQIPELAKRIKMFFALGPVASVAFCTSPMAKLGRLPDHLIKD
..::::.:::::.:::::: .::::..:::.:::.:.:.: :: .:. ::: .::
NP_001 KIYYVGYSQGTTMGFIAFSTMPELAQKIKMYFALAPIATVKHAKSPGTKFLLLPDMMIKG
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE4 LFGDKEFLPQSAFLKWLGTHVCTHVILKELCGNLCFLLCGFNERNLNMSRVDVYTTHSPA
::: :::: :. ::. : ..: .::: ..:.:. .:: ::: :.::::..::..:. :
NP_001 LFGKKEFLYQTRFLRQLVIYLCGQVILDQICSNIMLLLGGFNTNNMNMSRASVYAAHTLA
240 250 260 270 280 290
290 300 310 320 330 340
pF1KE4 GTSVQNMLHWSQAVKFQKFQAFDWGSSAKNYFHYNQSYPPTYNVKDMLVPTAVWSGGHDW
::::::.:::::::. ...:::::: .:: . :: : : :.:: ::::.:.::.::
NP_001 GTSVQNILHWSQAVNSGELRAFDWGSETKNLEKCNQPTPVRYRVRDMTVPTAMWTGGQDW
300 310 320 330 340 350
350 360 370 380 390
pF1KE4 LADVYDVNILLTQITNLVFHESIPEWEHLDFIWGLDAPWRLYNKIINLMRKYQ
:.. ::..::...:::..:..:::: :.::::::::: :.::.::.::..
NP_001 LSNPEDVKMLLSEVTNLIYHKNIPEWAHVDFIWGLDAPHRMYNEIIHLMQQEETNLSQGR
360 370 380 390 400 410
NP_001 CEAVL
420
>>XP_011538050 (OMIM: 613923) PREDICTED: lipase member M (430 aa)
initn: 1655 init1: 1119 opt: 1654 Z-score: 2105.8 bits: 398.6 E(85289): 1.5e-110
Smith-Waterman score: 1654; 59.7% identity (81.4% similar) in 404 aa overlap (1-397:15-416)
10 20 30 40
pF1KE4 MKMRFLGLVVCLVLWPLHSEGSGGKLTALDPETNMNVSEIISYWGF
:.: .: ::. . ..: : :.:::. ::.::::.. :.
XP_011 MLETLSRQWIVSHRMEMWLLILVAYMFQRNVNSVHMPTK--AVDPEAFMNISEIIQHQGY
10 20 30 40 50
50 60 70 80 90 100
pF1KE4 PSEEYLVETEDGYILCLNRIPHGRKNHSDKGPKPVVFLQHGLLADSSNWVTNLANSSLGF
: ::: : ::::::: .::::.: . . : .:::.:::::.. .:::..:: :.::::
XP_011 PCEEYEVATEDGYILSVNRIPRGLVQPKKTGSRPVVLLQHGLVGGASNWISNLPNNSLGF
60 70 80 90 100 110
110 120 130 140 150 160
pF1KE4 ILADAGFDVWMGNSRGNTWSRKHKTLSVSQDEFWAFSYDEMAKYDLPASINFILNKTGQE
:::::::::::::::::.:::::::::..:::::::::::::..:::: :::::.:::::
XP_011 ILADAGFDVWMGNSRGNAWSRKHKTLSIDQDEFWAFSYDEMARFDLPAVINFILQKTGQE
120 130 140 150 160 170
170 180 190 200 210 220
pF1KE4 QVYYVGHSQGTTIGFIAFSQIPELAKRIKMFFALGPVASVAFCTSPMAKLGRLPDHLIKD
..::::.:::::.:::::: .::::..:::.:::.:.:.: :: .:. ::: .::
XP_011 KIYYVGYSQGTTMGFIAFSTMPELAQKIKMYFALAPIATVKHAKSPGTKFLLLPDMMIKG
180 190 200 210 220 230
230 240 250 260 270
pF1KE4 LFGDKEFLPQSAFLKWLGTHVCTHVILKELCGNLCFLLCGFNERNLNM-------SRVDV
::: :::: :. ::. : ..: .::: ..:.:. .:: ::: :.:: ::..:
XP_011 LFGKKEFLYQTRFLRQLVIYLCGQVILDQICSNIMLLLGGFNTNNMNMNTHGLLQSRASV
240 250 260 270 280 290
280 290 300 310 320 330
pF1KE4 YTTHSPAGTSVQNMLHWSQAVKFQKFQAFDWGSSAKNYFHYNQSYPPTYNVKDMLVPTAV
:..:. :::::::.:::::::. ...:::::: .:: . :: : : :.:: ::::.
XP_011 YAAHTLAGTSVQNILHWSQAVNSGELRAFDWGSETKNLEKCNQPTPVRYRVRDMTVPTAM
300 310 320 330 340 350
340 350 360 370 380 390
pF1KE4 WSGGHDWLADVYDVNILLTQITNLVFHESIPEWEHLDFIWGLDAPWRLYNKIINLMRKYQ
:.::.:::.. ::..::...:::..:..:::: :.::::::::: :.::.::.::..
XP_011 WTGGQDWLSNPEDVKMLLSEVTNLIYHKNIPEWAHVDFIWGLDAPHRMYNEIIHLMQQEE
360 370 380 390 400 410
XP_011 TNLSQGRCEAVL
420 430
>>NP_001185758 (OMIM: 601980) gastric triacylglycerol li (408 aa)
initn: 1623 init1: 1623 opt: 1623 Z-score: 2066.6 bits: 391.3 E(85289): 2.3e-108
Smith-Waterman score: 1623; 57.9% identity (82.5% similar) in 394 aa overlap (2-395:10-403)
10 20 30 40 50
pF1KE4 MKMRFLGLVVCLVLWPLHSEGSGGKLTALDPETNMNVSEIISYWGFPSEEYL
:: .: .. :. ..: ::: .::..::.:..:.:::.:.:::
NP_001 MFSNANSRSKMWLLLTMASLISVLGTTHGLFGKLHPGSPEVTMNISQMITYWGYPNEEYE
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE4 VETEDGYILCLNRIPHGRKNHSDKGPKPVVFLQHGLLADSSNWVTNLANSSLGFILADAG
: ::::::: .::::.:.:: .. : .:::::::::::...::..:: :.::.:::::::
NP_001 VVTEDGYILEVNRIPYGKKNSGNTGQRPVVFLQHGLLASATNWISNLPNNSLAFILADAG
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE4 FDVWMGNSRGNTWSRKHKTLSVSQDEFWAFSYDEMAKYDLPASINFILNKTGQEQVYYVG
.:::.::::::::.:.. : .. ::::::.::::::::::.:.::..::::.:..:::
NP_001 YDVWLGNSRGNTWARRNLYYSPDSVEFWAFSFDEMAKYDLPATIDFIVKKTGQKQLHYVG
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE4 HSQGTTIGFIAFSQIPELAKRIKMFFALGPVASVAFCTSPMAKLGRLPDHLIKDLFGDKE
::::::::::::: : :::::: :.::.:::.: . : . :: .:. :.: .::::
NP_001 HSQGTTIGFIAFSTNPSLAKRIKTFYALAPVATVKYTKSLINKLRFVPQSLFKFIFGDKI
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE4 FLPQSAFLKWLGTHVCTHVILKELCGNLCFLLCGFNERNLNMSRVDVYTTHSPAGTSVQN
: :.. : ..:.:.::.. .:. ::.: :..:::. .:.: ::.::: .:.::::::::
NP_001 FYPHNFFDQFLATEVCSREMLNLLCSNALFIICGFDSKNFNTSRLDVYLSHNPAGTSVQN
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE4 MLHWSQAVKFQKFQAFDWGSSAKNYFHYNQSYPPTYNVKDMLVPTAVWSGGHDWLADVYD
:.::.:::: ::::.:::: ..: .::.:: :: ::: : :: :::.::.: ::: :
NP_001 MFHWTQAVKSGKFQAYDWGSPVQNRMHYDQSQPPYYNVTAMNVPIAVWNGGKDLLADPQD
310 320 330 340 350 360
360 370 380 390
pF1KE4 VNILLTQITNLVFHESIPEWEHLDFIWGLDAPWRLYNKIINLMRKYQ
:..:: .. ::..:. :: ..::::::..::: ..:: :....
NP_001 VGLLLPKLPNLIYHKEIPFYNHLDFIWAMDAPQEVYNDIVSMISEDKK
370 380 390 400
>>XP_011538613 (OMIM: 601980) PREDICTED: gastric triacyl (398 aa)
initn: 1616 init1: 1616 opt: 1619 Z-score: 2061.7 bits: 390.3 E(85289): 4.2e-108
Smith-Waterman score: 1619; 59.4% identity (84.1% similar) in 377 aa overlap (19-395:17-393)
10 20 30 40 50 60
pF1KE4 MKMRFLGLVVCLVLWPLHSEGSGGKLTALDPETNMNVSEIISYWGFPSEEYLVETEDGYI
..: ::: .::..::.:..:.:::.:.::: : ::::::
XP_011 MWLLLTMASLISVLGTTHGLFGKLHPGSPEVTMNISQMITYWGYPNEEYEVVTEDGYI
10 20 30 40 50
70 80 90 100 110 120
pF1KE4 LCLNRIPHGRKNHSDKGPKPVVFLQHGLLADSSNWVTNLANSSLGFILADAGFDVWMGNS
: .::::.:.:: .. : .:::::::::::...::..:: :.::.:::::::.:::.:::
XP_011 LEVNRIPYGKKNSGNTGQRPVVFLQHGLLASATNWISNLPNNSLAFILADAGYDVWLGNS
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE4 RGNTWSRKHKTLSVSQDEFWAFSYDEMAKYDLPASINFILNKTGQEQVYYVGHSQGTTIG
:::::.:.. : .. ::::::.::::::::::.:.::..::::.:..:::::::::::
XP_011 RGNTWARRNLYYSPDSVEFWAFSFDEMAKYDLPATIDFIVKKTGQKQLHYVGHSQGTTIG
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE4 FIAFSQIPELAKRIKMFFALGPVASVAFCTSPMAKLGRLPDHLIKDLFGDKEFLPQSAFL
::::: : :::::: :.::.:::.: . : . :: .:. :.: .:::: : :.. :
XP_011 FIAFSTNPSLAKRIKTFYALAPVATVKYTKSLINKLRFVPQSLFKFIFGDKIFYPHNFFD
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE4 KWLGTHVCTHVILKELCGNLCFLLCGFNERNLNMSRVDVYTTHSPAGTSVQNMLHWSQAV
..:.:.::.. .:. ::.: :..:::. .:.: ::.::: .:.:::::::::.::.:::
XP_011 QFLATEVCSREMLNLLCSNALFIICGFDSKNFNTSRLDVYLSHNPAGTSVQNMFHWTQAV
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE4 KFQKFQAFDWGSSAKNYFHYNQSYPPTYNVKDMLVPTAVWSGGHDWLADVYDVNILLTQI
: ::::.:::: ..: .::.:: :: ::: : :: :::.::.: ::: ::..:: ..
XP_011 KSGKFQAYDWGSPVQNRMHYDQSQPPYYNVTAMNVPIAVWNGGKDLLADPQDVGLLLPKL
300 310 320 330 340 350
370 380 390
pF1KE4 TNLVFHESIPEWEHLDFIWGLDAPWRLYNKIINLMRKYQ
::..:. :: ..::::::..::: ..:: :....
XP_011 PNLIYHKEIPFYNHLDFIWAMDAPQEVYNDIVSMISEDKK
360 370 380 390
>>NP_004181 (OMIM: 601980) gastric triacylglycerol lipas (398 aa)
initn: 1616 init1: 1616 opt: 1619 Z-score: 2061.7 bits: 390.3 E(85289): 4.2e-108
Smith-Waterman score: 1619; 59.4% identity (84.1% similar) in 377 aa overlap (19-395:17-393)
10 20 30 40 50 60
pF1KE4 MKMRFLGLVVCLVLWPLHSEGSGGKLTALDPETNMNVSEIISYWGFPSEEYLVETEDGYI
..: ::: .::..::.:..:.:::.:.::: : ::::::
NP_004 MWLLLTMASLISVLGTTHGLFGKLHPGSPEVTMNISQMITYWGYPNEEYEVVTEDGYI
10 20 30 40 50
70 80 90 100 110 120
pF1KE4 LCLNRIPHGRKNHSDKGPKPVVFLQHGLLADSSNWVTNLANSSLGFILADAGFDVWMGNS
: .::::.:.:: .. : .:::::::::::...::..:: :.::.:::::::.:::.:::
NP_004 LEVNRIPYGKKNSGNTGQRPVVFLQHGLLASATNWISNLPNNSLAFILADAGYDVWLGNS
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE4 RGNTWSRKHKTLSVSQDEFWAFSYDEMAKYDLPASINFILNKTGQEQVYYVGHSQGTTIG
:::::.:.. : .. ::::::.::::::::::.:.::..::::.:..:::::::::::
NP_004 RGNTWARRNLYYSPDSVEFWAFSFDEMAKYDLPATIDFIVKKTGQKQLHYVGHSQGTTIG
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE4 FIAFSQIPELAKRIKMFFALGPVASVAFCTSPMAKLGRLPDHLIKDLFGDKEFLPQSAFL
::::: : :::::: :.::.:::.: . : . :: .:. :.: .:::: : :.. :
NP_004 FIAFSTNPSLAKRIKTFYALAPVATVKYTKSLINKLRFVPQSLFKFIFGDKIFYPHNFFD
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE4 KWLGTHVCTHVILKELCGNLCFLLCGFNERNLNMSRVDVYTTHSPAGTSVQNMLHWSQAV
..:.:.::.. .:. ::.: :..:::. .:.: ::.::: .:.:::::::::.::.:::
NP_004 QFLATEVCSREMLNLLCSNALFIICGFDSKNFNTSRLDVYLSHNPAGTSVQNMFHWTQAV
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE4 KFQKFQAFDWGSSAKNYFHYNQSYPPTYNVKDMLVPTAVWSGGHDWLADVYDVNILLTQI
: ::::.:::: ..: .::.:: :: ::: : :: :::.::.: ::: ::..:: ..
NP_004 KSGKFQAYDWGSPVQNRMHYDQSQPPYYNVTAMNVPIAVWNGGKDLLADPQDVGLLLPKL
300 310 320 330 340 350
370 380 390
pF1KE4 TNLVFHESIPEWEHLDFIWGLDAPWRLYNKIINLMRKYQ
::..:. :: ..::::::..::: ..:: :....
NP_004 PNLIYHKEIPFYNHLDFIWAMDAPQEVYNDIVSMISEDKK
360 370 380 390
>>XP_011538377 (OMIM: 613922) PREDICTED: lipase member K (408 aa)
initn: 1567 init1: 1567 opt: 1574 Z-score: 2004.2 bits: 379.7 E(85289): 6.7e-105
Smith-Waterman score: 1574; 56.4% identity (80.9% similar) in 397 aa overlap (2-398:9-405)
10 20 30 40 50
pF1KE4 MKMRFLGLVVCLVLWPLHSEGSGGKLTALDPETNMNVSEIISYWGFPSEEYLV
.: : ..: .: : : . .::.:::.:.::::::.: ::: :
XP_011 MESLLGRSQMWQLLAAACWMLLLGSMYGYDKKGNNANPEANMNISQIISYWGYPYEEYDV
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE4 ETEDGYILCLNRIPHGRKNHSDKGPKPVVFLQHGLLADSSNWVTNLANSSLGFILADAGF
:.::::: . :::::: . .:::.:.:::::.:..:::. :: :.::.:.:::.:.
XP_011 TTKDGYILGIYRIPHGRGCPGRTAPKPAVYLQHGLIASASNWICNLPNNSLAFLLADSGY
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE4 DVWMGNSRGNTWSRKHKTLSVSQDEFWAFSYDEMAKYDLPASINFILNKTGQEQVYYVGH
:::.:::::::::::: :: .. :.:::: ::::::::::.::::..::::...:::::
XP_011 DVWLGNSRGNTWSRKHLKLSPKSPEYWAFSLDEMAKYDLPATINFIIEKTGQKRLYYVGH
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE4 SQGTTIGFIAFSQIPELAKRIKMFFALGPVASVAFCTSPMAKLGRLPDHLIKDLFGDKEF
::::::.::::: :::::.::.::::.::..: . ::: :: : ...: ::::: :
XP_011 SQGTTIAFIAFSTNPELAKKIKIFFALAPVVTVKYTQSPMKKLTTLSRRVVKVLFGDKMF
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE4 LPQSAFLKWLGTHVCTHVILKELCGNLCFLLCGFNERNLNMSRVDVYTTHSPAGTSVQNM
:.. : ....:.::.. .....:.:. : : ::. .::::::.::: .:.:::::::::
XP_011 HPHTLFDQFIATKVCNRKLFRRICSNFLFTLSGFDPQNLNMSRLDVYLSHNPAGTSVQNM
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE4 LHWSQAVKFQKFQAFDWGSSAKNYFHYNQSYPPTYNVKDMLVPTAVWSGGHDWLADVYDV
:::.:::. ..::::::.: .:..:..: :: ::. : ::::.:.::.: .:: ::
XP_011 LHWAQAVNSGQLQAFDWGNSDQNMMHFHQLTPPLYNITKMEVPTAIWNGGQDIVADPKDV
310 320 330 340 350 360
360 370 380 390
pF1KE4 NILLTQITNLVFHESIPEWEHLDFIWGLDAPWRLYNKIINLMRKYQ
. :: ::.::.... ::...:.:: : ::: ..:. .: ::..:
XP_011 ENLLPQIANLIYYKLIPHYNHVDFYLGEDAPQEIYQDLIILMEEYLQN
370 380 390 400
>>XP_011538375 (OMIM: 613922) PREDICTED: lipase member K (419 aa)
initn: 1567 init1: 1567 opt: 1574 Z-score: 2004.1 bits: 379.7 E(85289): 6.9e-105
Smith-Waterman score: 1574; 56.4% identity (80.9% similar) in 397 aa overlap (2-398:20-416)
10 20 30 40
pF1KE4 MKMRFLGLVVCLVLWPLHSEGSGGKLTALDPETNMNVSEIIS
.: : ..: .: : : . .::.:::.:.:::
XP_011 MHLKLPGLEDRPPKTWIRSQMWQLLAAACWMLLLGSMYGYDKKGNNANPEANMNISQIIS
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE4 YWGFPSEEYLVETEDGYILCLNRIPHGRKNHSDKGPKPVVFLQHGLLADSSNWVTNLANS
:::.: ::: : :.::::: . :::::: . .:::.:.:::::.:..:::. :: :.
XP_011 YWGYPYEEYDVTTKDGYILGIYRIPHGRGCPGRTAPKPAVYLQHGLIASASNWICNLPNN
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE4 SLGFILADAGFDVWMGNSRGNTWSRKHKTLSVSQDEFWAFSYDEMAKYDLPASINFILNK
::.:.:::.:.:::.:::::::::::: :: .. :.:::: ::::::::::.::::..:
XP_011 SLAFLLADSGYDVWLGNSRGNTWSRKHLKLSPKSPEYWAFSLDEMAKYDLPATINFIIEK
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE4 TGQEQVYYVGHSQGTTIGFIAFSQIPELAKRIKMFFALGPVASVAFCTSPMAKLGRLPDH
:::...:::::::::::.::::: :::::.::.::::.::..: . ::: :: : .
XP_011 TGQKRLYYVGHSQGTTIAFIAFSTNPELAKKIKIFFALAPVVTVKYTQSPMKKLTTLSRR
190 200 210 220 230 240
230 240 250 260 270 280
pF1KE4 LIKDLFGDKEFLPQSAFLKWLGTHVCTHVILKELCGNLCFLLCGFNERNLNMSRVDVYTT
..: ::::: : :.. : ....:.::.. .....:.:. : : ::. .::::::.::: .
XP_011 VVKVLFGDKMFHPHTLFDQFIATKVCNRKLFRRICSNFLFTLSGFDPQNLNMSRLDVYLS
250 260 270 280 290 300
290 300 310 320 330 340
pF1KE4 HSPAGTSVQNMLHWSQAVKFQKFQAFDWGSSAKNYFHYNQSYPPTYNVKDMLVPTAVWSG
:.::::::::::::.:::. ..::::::.: .:..:..: :: ::. : ::::.:.:
XP_011 HNPAGTSVQNMLHWAQAVNSGQLQAFDWGNSDQNMMHFHQLTPPLYNITKMEVPTAIWNG
310 320 330 340 350 360
350 360 370 380 390
pF1KE4 GHDWLADVYDVNILLTQITNLVFHESIPEWEHLDFIWGLDAPWRLYNKIINLMRKYQ
:.: .:: ::. :: ::.::.... ::...:.:: : ::: ..:. .: ::..:
XP_011 GQDIVADPKDVENLLPQIANLIYYKLIPHYNHVDFYLGEDAPQEIYQDLIILMEEYLQN
370 380 390 400 410
399 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 23:00:32 2016 done: Sat Nov 5 23:00:33 2016
Total Scan time: 6.060 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]