Result of FASTA (omim) for
pFN21AE4372
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE4372, 390 aa
1>>>pF1KE4372 390 - 390 aa - 390 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.6082+/-0.000369; mu= 15.3303+/- 0.023
mean_var=68.7297+/-14.140, 0's: 0 Z-trim(112.7): 26 B-trim: 1134 in 1/54
Lambda= 0.154704
statistics sampled from 21694 (21711) to 21694 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.628), E-opt: 0.2 (0.255), width: 16
Scan time: 7.480
The best scores are: opt bits E(85289)
NP_000275 (OMIM: 300502,312170) pyruvate dehydroge ( 390) 2624 594.8 1.2e-169
NP_001166926 (OMIM: 300502,312170) pyruvate dehydr ( 397) 2600 589.4 4.8e-168
NP_001166925 (OMIM: 300502,312170) pyruvate dehydr ( 428) 2511 569.6 4.9e-162
NP_005381 (OMIM: 179061) pyruvate dehydrogenase E1 ( 388) 2263 514.2 2.1e-145
XP_016885063 (OMIM: 300502,312170) PREDICTED: pyru ( 397) 1304 300.2 5.7e-81
NP_001166927 (OMIM: 300502,312170) pyruvate dehydr ( 359) 1285 295.9 9.9e-80
NP_000700 (OMIM: 248600,608348) 2-oxoisovalerate d ( 445) 424 103.8 8.4e-22
NP_001158255 (OMIM: 248600,608348) 2-oxoisovalerat ( 444) 423 103.6 9.8e-22
NP_061176 (OMIM: 204750,614984,615025) probable 2- ( 919) 167 46.6 0.00029
>>NP_000275 (OMIM: 300502,312170) pyruvate dehydrogenase (390 aa)
initn: 2624 init1: 2624 opt: 2624 Z-score: 3166.9 bits: 594.8 E(85289): 1.2e-169
Smith-Waterman score: 2624; 100.0% identity (100.0% similar) in 390 aa overlap (1-390:1-390)
10 20 30 40 50 60
pF1KE4 MRKMLAAVSRVLSGASQKPASRVLVASRNFANDATFEIKKCDLHRLEEGPPVTTVLTRED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MRKMLAAVSRVLSGASQKPASRVLVASRNFANDATFEIKKCDLHRLEEGPPVTTVLTRED
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 GLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITAYRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 GLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITAYRA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 HGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 HGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 CKYNGKDEVCLTLYGDGAANQGQIFEAYNMAALWKLPCIFICENNRYGMGTSVERAAAST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 CKYNGKDEVCLTLYGDGAANQGQIFEAYNMAALWKLPCIFICENNRYGMGTSVERAAAST
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 DYYKRGDFIPGLRVDGMDILCVREATRFAAAYCRSGKGPILMELQTYRYHGHSMSDPGVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 DYYKRGDFIPGLRVDGMDILCVREATRFAAAYCRSGKGPILMELQTYRYHGHSMSDPGVS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 YRTREEIQEVRSKSDPIMLLKDRMVNSNLASVEELKEIDVEVRKEIEDAAQFATADPEPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 YRTREEIQEVRSKSDPIMLLKDRMVNSNLASVEELKEIDVEVRKEIEDAAQFATADPEPP
310 320 330 340 350 360
370 380 390
pF1KE4 LEELGYHIYSSDPPFEVRGANQWIKFKSVS
::::::::::::::::::::::::::::::
NP_000 LEELGYHIYSSDPPFEVRGANQWIKFKSVS
370 380 390
>>NP_001166926 (OMIM: 300502,312170) pyruvate dehydrogen (397 aa)
initn: 1992 init1: 1992 opt: 2600 Z-score: 3137.9 bits: 589.4 E(85289): 4.8e-168
Smith-Waterman score: 2600; 98.2% identity (98.2% similar) in 397 aa overlap (1-390:1-397)
10 20 30 40 50 60
pF1KE4 MRKMLAAVSRVLSGASQKPASRVLVASRNFANDATFEIKKCDLHRLEEGPPVTTVLTRED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MRKMLAAVSRVLSGASQKPASRVLVASRNFANDATFEIKKCDLHRLEEGPPVTTVLTRED
10 20 30 40 50 60
70 80 90 100 110
pF1KE4 GLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQ-------EACCVGLEAGINPTDH
::::::::::::::::::::::::::::::::::::: ::::::::::::::::
NP_001 GLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQFLLPLTQEACCVGLEAGINPTDH
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE4 LITAYRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LITAYRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPL
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE4 GAGIALACKYNGKDEVCLTLYGDGAANQGQIFEAYNMAALWKLPCIFICENNRYGMGTSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GAGIALACKYNGKDEVCLTLYGDGAANQGQIFEAYNMAALWKLPCIFICENNRYGMGTSV
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE4 ERAAASTDYYKRGDFIPGLRVDGMDILCVREATRFAAAYCRSGKGPILMELQTYRYHGHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ERAAASTDYYKRGDFIPGLRVDGMDILCVREATRFAAAYCRSGKGPILMELQTYRYHGHS
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE4 MSDPGVSYRTREEIQEVRSKSDPIMLLKDRMVNSNLASVEELKEIDVEVRKEIEDAAQFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSDPGVSYRTREEIQEVRSKSDPIMLLKDRMVNSNLASVEELKEIDVEVRKEIEDAAQFA
310 320 330 340 350 360
360 370 380 390
pF1KE4 TADPEPPLEELGYHIYSSDPPFEVRGANQWIKFKSVS
:::::::::::::::::::::::::::::::::::::
NP_001 TADPEPPLEELGYHIYSSDPPFEVRGANQWIKFKSVS
370 380 390
>>NP_001166925 (OMIM: 300502,312170) pyruvate dehydrogen (428 aa)
initn: 2511 init1: 2511 opt: 2511 Z-score: 3030.0 bits: 569.6 E(85289): 4.9e-162
Smith-Waterman score: 2511; 99.5% identity (99.7% similar) in 373 aa overlap (18-390:56-428)
10 20 30 40
pF1KE4 MRKMLAAVSRVLSGASQKPASRVLVASRNFANDATFEIKKCDLHRLE
. ::::::::::::::::::::::::::::
NP_001 LPSLVSISRLKQSSHLGLPKCWDYSHSLKTRQASRVLVASRNFANDATFEIKKCDLHRLE
30 40 50 60 70 80
50 60 70 80 90 100
pF1KE4 EGPPVTTVLTREDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EGPPVTTVLTREDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAG
90 100 110 120 130 140
110 120 130 140 150 160
pF1KE4 INPTDHLITAYRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHMYAKNFYGGNGIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 INPTDHLITAYRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHMYAKNFYGGNGIV
150 160 170 180 190 200
170 180 190 200 210 220
pF1KE4 GAQVPLGAGIALACKYNGKDEVCLTLYGDGAANQGQIFEAYNMAALWKLPCIFICENNRY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GAQVPLGAGIALACKYNGKDEVCLTLYGDGAANQGQIFEAYNMAALWKLPCIFICENNRY
210 220 230 240 250 260
230 240 250 260 270 280
pF1KE4 GMGTSVERAAASTDYYKRGDFIPGLRVDGMDILCVREATRFAAAYCRSGKGPILMELQTY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GMGTSVERAAASTDYYKRGDFIPGLRVDGMDILCVREATRFAAAYCRSGKGPILMELQTY
270 280 290 300 310 320
290 300 310 320 330 340
pF1KE4 RYHGHSMSDPGVSYRTREEIQEVRSKSDPIMLLKDRMVNSNLASVEELKEIDVEVRKEIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RYHGHSMSDPGVSYRTREEIQEVRSKSDPIMLLKDRMVNSNLASVEELKEIDVEVRKEIE
330 340 350 360 370 380
350 360 370 380 390
pF1KE4 DAAQFATADPEPPLEELGYHIYSSDPPFEVRGANQWIKFKSVS
:::::::::::::::::::::::::::::::::::::::::::
NP_001 DAAQFATADPEPPLEELGYHIYSSDPPFEVRGANQWIKFKSVS
390 400 410 420
>>NP_005381 (OMIM: 179061) pyruvate dehydrogenase E1 com (388 aa)
initn: 2256 init1: 2256 opt: 2263 Z-score: 2731.5 bits: 514.2 E(85289): 2.1e-145
Smith-Waterman score: 2263; 85.8% identity (94.1% similar) in 388 aa overlap (4-390:1-388)
10 20 30 40 50
pF1KE4 MRKMLAA-VSRVLSGASQKPASRVLVASRNFANDATFEIKKCDLHRLEEGPPVTTVLTRE
:::: .:::: ..:: : :::::::: .::::::::::::. :::::::::::::
NP_005 MLAAFISRVLRRVAQKSARRVLVASRNSSNDATFEIKKCDLYLLEEGPPVTTVLTRA
10 20 30 40 50
60 70 80 90 100 110
pF1KE4 DGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITAYR
.:::::::: ::::::::::::::::.::::::::::::::::::::::::.::.::.::
NP_005 EGLKYYRMMLTVRRMELKADQLYKQKFIRGFCHLCDGQEACCVGLEAGINPSDHVITSYR
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE4 AHGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGIAL
::: .::::::: ::::::::.::::::::::::::.::::::::::::: ::::::::
NP_005 AHGVCYTRGLSVRSILAELTGRRGGCAKGKGGSMHMYTKNFYGGNGIVGAQGPLGAGIAL
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE4 ACKYNGKDEVCLTLYGDGAANQGQIFEAYNMAALWKLPCIFICENNRYGMGTSVERAAAS
::::.:.::.::::::::::::::: ::.::::::::::.:::::: ::::::.::::::
NP_005 ACKYKGNDEICLTLYGDGAANQGQIAEAFNMAALWKLPCVFICENNLYGMGTSTERAAAS
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE4 TDYYKRGDFIPGLRVDGMDILCVREATRFAAAYCRSGKGPILMELQTYRYHGHSMSDPGV
::::::.:::::.:::::.:::::::.::: ::::::::::::::::::::::::::::
NP_005 PDYYKRGNFIPGLKVDGMDVLCVREATKFAANYCRSGKGPILMELQTYRYHGHSMSDPGV
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE4 SYRTREEIQEVRSKSDPIMLLKDRMVNSNLASVEELKEIDVEVRKEIEDAAQFATADPEP
:::::::::::::: :::..:.::::::.::.::::::: .::::::.:::::::.::::
NP_005 SYRTREEIQEVRSKRDPIIILQDRMVNSKLATVEELKEIGAEVRKEIDDAAQFATTDPEP
300 310 320 330 340 350
360 370 380 390
pF1KE4 PLEELGYHIYSSDPPFEVRGANQWIKFKSVS
:::::.:::::: ::::::: ::::::::
NP_005 HLEELGHHIYSSDSSFEVRGANPWIKFKSVS
360 370 380
>>XP_016885063 (OMIM: 300502,312170) PREDICTED: pyruvate (397 aa)
initn: 1381 init1: 1280 opt: 1304 Z-score: 1574.6 bits: 300.2 E(85289): 5.7e-81
Smith-Waterman score: 2254; 83.9% identity (83.9% similar) in 428 aa overlap (1-390:1-397)
10 20
pF1KE4 MRKMLAAVSRVLSGASQKP--------------------------------------ASR
::::::::::::::::::: :::
XP_016 MRKMLAAVSRVLSGASQKPRHGLATLPSLVSISRLKQSSHLGLPKCWDYSHSLKTRQASR
10 20 30 40 50 60
30 40 50 60 70 80
pF1KE4 VLVASRNFANDATFEIKKCDLHRLEEGPPVTTVLTREDGLKYYRMMQTVRRMELKADQLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLVASRNFANDATFEIKKCDLHRLEEGPPVTTVLTREDGLKYYRMMQTVRRMELKADQLY
70 80 90 100 110 120
90 100 110 120 130 140
pF1KE4 KQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITAYRAHGFTFTRGLSVREILAELTGRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITAYRAHGFTFTRGLSVREILAELTGRK
130 140 150 160 170 180
150 160 170 180 190 200
pF1KE4 GGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALACKYNGKDEVCLTLYGDGAANQG
:::::::::::::::::::::::::::: :
XP_016 GGCAKGKGGSMHMYAKNFYGGNGIVGAQ-------------------------------G
190 200
210 220 230 240 250 260
pF1KE4 QIFEAYNMAALWKLPCIFICENNRYGMGTSVERAAASTDYYKRGDFIPGLRVDGMDILCV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QIFEAYNMAALWKLPCIFICENNRYGMGTSVERAAASTDYYKRGDFIPGLRVDGMDILCV
210 220 230 240 250 260
270 280 290 300 310 320
pF1KE4 REATRFAAAYCRSGKGPILMELQTYRYHGHSMSDPGVSYRTREEIQEVRSKSDPIMLLKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 REATRFAAAYCRSGKGPILMELQTYRYHGHSMSDPGVSYRTREEIQEVRSKSDPIMLLKD
270 280 290 300 310 320
330 340 350 360 370 380
pF1KE4 RMVNSNLASVEELKEIDVEVRKEIEDAAQFATADPEPPLEELGYHIYSSDPPFEVRGANQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RMVNSNLASVEELKEIDVEVRKEIEDAAQFATADPEPPLEELGYHIYSSDPPFEVRGANQ
330 340 350 360 370 380
390
pF1KE4 WIKFKSVS
::::::::
XP_016 WIKFKSVS
390
>>NP_001166927 (OMIM: 300502,312170) pyruvate dehydrogen (359 aa)
initn: 1280 init1: 1280 opt: 1285 Z-score: 1552.4 bits: 295.9 E(85289): 9.9e-80
Smith-Waterman score: 2340; 92.1% identity (92.1% similar) in 390 aa overlap (1-390:1-359)
10 20 30 40 50 60
pF1KE4 MRKMLAAVSRVLSGASQKPASRVLVASRNFANDATFEIKKCDLHRLEEGPPVTTVLTRED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MRKMLAAVSRVLSGASQKPASRVLVASRNFANDATFEIKKCDLHRLEEGPPVTTVLTRED
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 GLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITAYRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITAYRA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 HGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALA
::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHMYAKNFYGGNGIVGAQ----------
130 140 150 160 170
190 200 210 220 230 240
pF1KE4 CKYNGKDEVCLTLYGDGAANQGQIFEAYNMAALWKLPCIFICENNRYGMGTSVERAAAST
:::::::::::::::::::::::::::::::::::::::
NP_001 ---------------------GQIFEAYNMAALWKLPCIFICENNRYGMGTSVERAAAST
180 190 200
250 260 270 280 290 300
pF1KE4 DYYKRGDFIPGLRVDGMDILCVREATRFAAAYCRSGKGPILMELQTYRYHGHSMSDPGVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DYYKRGDFIPGLRVDGMDILCVREATRFAAAYCRSGKGPILMELQTYRYHGHSMSDPGVS
210 220 230 240 250 260
310 320 330 340 350 360
pF1KE4 YRTREEIQEVRSKSDPIMLLKDRMVNSNLASVEELKEIDVEVRKEIEDAAQFATADPEPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YRTREEIQEVRSKSDPIMLLKDRMVNSNLASVEELKEIDVEVRKEIEDAAQFATADPEPP
270 280 290 300 310 320
370 380 390
pF1KE4 LEELGYHIYSSDPPFEVRGANQWIKFKSVS
::::::::::::::::::::::::::::::
NP_001 LEELGYHIYSSDPPFEVRGANQWIKFKSVS
330 340 350
>>NP_000700 (OMIM: 248600,608348) 2-oxoisovalerate dehyd (445 aa)
initn: 215 init1: 163 opt: 424 Z-score: 512.4 bits: 103.8 E(85289): 8.4e-22
Smith-Waterman score: 424; 27.6% identity (56.5% similar) in 322 aa overlap (56-373:97-417)
30 40 50 60 70 80
pF1KE4 ASRNFANDATFEIKKCDLHRLEEGPPVTTVLTREDGLKYYRMMQTVRRMELKADQLYKQK
: .: :: :. : . :. . .:
NP_000 FIQPNVISGIPIYRVMDRQGQIINPSEDPHLPKEKVLKLYKSMTLLNTMDRILYESQRQG
70 80 90 100 110 120
90 100 110 120 130 140
pF1KE4 IIRGFCHLCDGQEACCVGLEAGINPTDHLITAYRAHGFTFTRGLSVREILAELTGRKGGC
: .: :.:. :: :... :: .. :: : . : .. ..:. : .
NP_000 RI-SFYMTNYGEEGTHVGSAAALDNTDLVFGQYREAGVLMYRDYPLELFMAQCYGNISDL
130 140 150 160 170 180
150 160 170 180 190 200
pF1KE4 AKGKGGSMHMYAK--NFYGGNGIVGAQVPLGAGIALACKYNGKDEVCLTLYGDGAANQGQ
.::. .:. : .: .. ...:.: ..: : : : . ..: . .:.:::..:.
NP_000 GKGRQMPVHYGCKERHFVTISSPLATQIPQAVGAAYAAKRANANRVVICYFGEGAASEGD
190 200 210 220 230 240
210 220 230 240 250 260
pF1KE4 IFEAYNMAALWKLPCIFICENNRYGMGTSVERAAASTDYYKRGDF--IPGLRVDGMDILC
..:.:: . : ::.:.:: :...: . . . :: : ..:::: :..
NP_000 AHAGFNFAATLECPIIFFCRNNGYAISTPTSEQYRGDGIAARGPGYGIMSIRVDGNDVFA
250 260 270 280 290 300
270 280 290 300 310 320
pF1KE4 VREATRFAAAYCRSGKGPILMELQTYRYHGHSMSDPGVSYRTREEIQEVRSKSDPIMLLK
: .::. : . . :.:.: .::: :: :: . .::. .:.. ... :: :.
NP_000 VYNATKEARRRAVAENQPFLIEAMTYRIGHHSTSDDSSAYRSVDEVNYWDKQDHPISRLR
310 320 330 340 350 360
330 340 350 360 370 380
pF1KE4 DRMVNSNLASVEELKEIDVEVRKEIEDAAQFATADPEPPLEELGYHIYSSDPPFEVRGAN
..... . :. : . :... .: . : :.: . : .:. :
NP_000 HYLLSQGWWDEEQEKAWRKQSRRKVMEAFEQAERKPKPNPNLLFSDVYQEMPAQLRKQQE
370 380 390 400 410 420
390
pF1KE4 QWIKFKSVS
NP_000 SLARHLQTYGEHYPLDHFDK
430 440
>>NP_001158255 (OMIM: 248600,608348) 2-oxoisovalerate de (444 aa)
initn: 343 init1: 161 opt: 423 Z-score: 511.2 bits: 103.6 E(85289): 9.8e-22
Smith-Waterman score: 423; 28.4% identity (56.4% similar) in 328 aa overlap (56-373:97-416)
30 40 50 60 70 80
pF1KE4 ASRNFANDATFEIKKCDLHRLEEGPPVTTVLTREDGLKYYRMMQTVRRMELKADQLYKQK
: .: :: :. : . :. . .:
NP_001 FIQPNVISGIPIYRVMDRQGQIINPSEDPHLPKEKVLKLYKSMTLLNTMDRILYESQRQG
70 80 90 100 110 120
90 100 110 120 130 140
pF1KE4 IIRGFCHLCDGQEACCVGLEAGINPTDHLITAYRAHGFTFTRGLSVREILAELTGRKGGC
: .: :.:. :: :... :: .. :: : . : .. ..:. : .
NP_001 RI-SFYMTNYGEEGTHVGSAAALDNTDLVFGQYREAGVLMYRDYPLELFMAQCYGNISDL
130 140 150 160 170 180
150 160 170 180 190 200
pF1KE4 AKGKGGSMHMYAK--NFYGGNGIVGAQVPLGAGIALACKYNGKDEVCLTLYGDGAANQGQ
.::. .:. : .: .. ...:.: ..: : : : . ..: . .:.:::..:.
NP_001 GKGRQMPVHYGCKERHFVTISSPLATQIPQAVGAAYAAKRANANRVVICYFGEGAASEGD
190 200 210 220 230 240
210 220 230 240 250
pF1KE4 IFEAYNMAALWKLPCIFICENNRYGMGTSVERAAASTDYYKRGDFI---PG-----LRVD
..:.:: . : ::.:.:: :...: ... : ::: : :: .:::
NP_001 AHAGFNFAATLECPIIFFCRNNGYAISTP------TSEQY-RGDGIARGPGYGIMSIRVD
250 260 270 280 290
260 270 280 290 300 310
pF1KE4 GMDILCVREATRFAAAYCRSGKGPILMELQTYRYHGHSMSDPGVSYRTREEIQEVRSKSD
: :.. : .::. : . . :.:.: .::: :: :: . .::. .:.. ...
NP_001 GNDVFAVYNATKEARRRAVAENQPFLIEAMTYRIGHHSTSDDSSAYRSVDEVNYWDKQDH
300 310 320 330 340 350
320 330 340 350 360 370
pF1KE4 PIMLLKDRMVNSNLASVEELKEIDVEVRKEIEDAAQFATADPEPPLEELGYHIYSSDPPF
:: :. ..... . :. : . :... .: . : :.: . : .:. :
NP_001 PISRLRHYLLSQGWWDEEQEKAWRKQSRRKVMEAFEQAERKPKPNPNLLFSDVYQEMPAQ
360 370 380 390 400 410
380 390
pF1KE4 EVRGANQWIKFKSVS
NP_001 LRKQQESLARHLQTYGEHYPLDHFDK
420 430 440
>>NP_061176 (OMIM: 204750,614984,615025) probable 2-oxog (919 aa)
initn: 74 init1: 74 opt: 167 Z-score: 197.5 bits: 46.6 E(85289): 0.00029
Smith-Waterman score: 167; 25.3% identity (55.8% similar) in 190 aa overlap (185-367:322-508)
160 170 180 190 200 210
pF1KE4 MYAKNFYGGNGIVGAQVPLGAGIALACKYNGKDEVCLTLYGDGA-ANQGQIFEAYNMAAL
: .:: ..::.. .:: . :..... :
NP_061 AVNPVAVGKTRGRQQSRQDGDYSPDNSAQPGDRVICLQVHGDASFCGQGIVPETFTLSNL
300 310 320 330 340 350
220 230 240 250 260
pF1KE4 WKL---PCIFICENNRYGMGTSVERAAASTDYYKRGDFIPG--LRVDGMDILCVREATRF
.. . . ::. :. : .::. .: : .. ..:.: . : .:::.
NP_061 PHFRIGGSVHLIVNNQLGYTTPAERGRSSLYCSDIGKLVGCAIIHVNGDSPEEVVRATRL
360 370 380 390 400 410
270 280 290 300 310 320
pF1KE4 AAAYCRSGKGPILMELQTYRYHGHS-MSDPGVSYRTREEIQEVRSKSDPIMLLKDRMVNS
: : :. . ....: :: ::. ...: . .: ..: :: : .... .
NP_061 AFEYQRQFRKDVIIDLLCYRQWGHNELDEPFYTNPIMYKIIRAR-KSIPDTY-AEHLIAG
420 430 440 450 460
330 340 350 360 370 380
pF1KE4 NLASVEELKEIDVEVRKEIEDAAQFATADPEPPLEELGYHIYSSDPPFEVRGANQWIKFK
.: . ::..:: ...: . : .:: .: :
NP_061 GLMTQEEVSEIKSSYYAKLNDHLN-NMAHYRPPALNLQAHWQGLAQPEAQITTWSTGVPL
470 480 490 500 510 520
390
pF1KE4 SVS
NP_061 DLLRFVGMKSVEVPRELQMHSHLLKTHVQSRMEKMMDGIKLDWATAEALALGSLLAQGFN
530 540 550 560 570 580
390 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 23:06:22 2016 done: Sat Nov 5 23:06:23 2016
Total Scan time: 7.480 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]