Result of FASTA (omim) for
pFN21AE4364
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE4364, 381 aa
1>>>pF1KE4364 381 - 381 aa - 381 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.4468+/-0.000381; mu= 16.0281+/- 0.024
mean_var=67.4315+/-13.558, 0's: 0 Z-trim(112.5): 30 B-trim: 879 in 1/53
Lambda= 0.156186
statistics sampled from 21382 (21411) to 21382 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.641), E-opt: 0.2 (0.251), width: 16
Scan time: 8.310
The best scores are: opt bits E(85289)
XP_016881729 (OMIM: 123310) PREDICTED: creatine ki ( 381) 2578 590.0 3.1e-168
NP_001815 (OMIM: 123310) creatine kinase M-type [H ( 381) 2578 590.0 3.1e-168
NP_001814 (OMIM: 123280) creatine kinase B-type [H ( 381) 2159 495.6 8.2e-140
NP_001015001 (OMIM: 613415) creatine kinase U-type ( 417) 1679 387.4 3.2e-107
NP_066270 (OMIM: 123290) creatine kinase U-type, m ( 417) 1679 387.4 3.2e-107
XP_011519499 (OMIM: 123290) PREDICTED: creatine ki ( 417) 1679 387.4 3.2e-107
NP_001308855 (OMIM: 613415) creatine kinase U-type ( 417) 1679 387.4 3.2e-107
XP_011519500 (OMIM: 123290) PREDICTED: creatine ki ( 376) 1672 385.8 8.8e-107
NP_001308856 (OMIM: 613415) creatine kinase U-type ( 448) 1672 385.9 1e-106
XP_016877858 (OMIM: 613415) PREDICTED: creatine ki ( 448) 1672 385.9 1e-106
XP_016877859 (OMIM: 613415) PREDICTED: creatine ki ( 448) 1672 385.9 1e-106
XP_011519498 (OMIM: 123290) PREDICTED: creatine ki ( 448) 1672 385.9 1e-106
XP_011519497 (OMIM: 123290) PREDICTED: creatine ki ( 448) 1672 385.9 1e-106
XP_011519496 (OMIM: 123290) PREDICTED: creatine ki ( 448) 1672 385.9 1e-106
NP_001308857 (OMIM: 613415) creatine kinase U-type ( 448) 1672 385.9 1e-106
NP_001093205 (OMIM: 123295) creatine kinase S-type ( 419) 1655 382.0 1.4e-105
NP_001093206 (OMIM: 123295) creatine kinase S-type ( 419) 1655 382.0 1.4e-105
NP_001816 (OMIM: 123295) creatine kinase S-type, m ( 419) 1655 382.0 1.4e-105
XP_016876440 (OMIM: 123280) PREDICTED: creatine ki ( 405) 1514 350.2 4.9e-96
XP_016876441 (OMIM: 123280) PREDICTED: creatine ki ( 217) 1261 293.1 4.2e-79
XP_011519501 (OMIM: 123290) PREDICTED: creatine ki ( 258) 1204 280.3 3.6e-75
XP_005254555 (OMIM: 613415) PREDICTED: creatine ki ( 258) 1204 280.3 3.6e-75
NP_001308858 (OMIM: 613415) creatine kinase U-type ( 258) 1204 280.3 3.6e-75
XP_016877391 (OMIM: 123290) PREDICTED: creatine ki ( 258) 1204 280.3 3.6e-75
XP_005254207 (OMIM: 123290) PREDICTED: creatine ki ( 258) 1204 280.3 3.6e-75
XP_016877860 (OMIM: 613415) PREDICTED: creatine ki ( 216) 446 109.4 8e-24
>>XP_016881729 (OMIM: 123310) PREDICTED: creatine kinase (381 aa)
initn: 2578 init1: 2578 opt: 2578 Z-score: 3141.3 bits: 590.0 E(85289): 3.1e-168
Smith-Waterman score: 2578; 99.7% identity (100.0% similar) in 381 aa overlap (1-381:1-381)
10 20 30 40 50 60
pF1KE4 MPFGNTHNKFKLNYKPEEEYPDLSKHNNHMAKVLTLELYKKLRDKETPSGFTVDDVIQTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MPFGNTHNKFKLNYKPEEEYPDLSKHNNHMAKVLTLELYKKLRDKETPSGFTVDDVIQTG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 VDNPGHPFIMTVGCVAGDEESYEVFKELFDPIISDRHGGYKPTDKHKTDLNHENLKGGDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VDNPGHPFIMTVGCVAGDEESYEVFKELFDPIISDRHGGYKPTDKHKTDLNHENLKGGDD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 LDPNYVLSSRVRTGRSIKGYTLPPHCSRGERRAVEKLSVEALNSLTGEFKGKYYPLKSMT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LDPNYVLSSRVRTGRSIKGYTLPPHCSRGERRAVEKLSVEALNSLTGEFKGKYYPLKSMT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 EKEQQQLIDDHFLFDKPVSPLLLASGMARDWPDARGIWHNDNKSLLVWVNEEDHLRVISM
::::::::::::::::::::::::::::::::::::::::::::.:::::::::::::::
XP_016 EKEQQQLIDDHFLFDKPVSPLLLASGMARDWPDARGIWHNDNKSFLVWVNEEDHLRVISM
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 EKGGNMKEVFRRFCVGLQKIEEIFKKAGHPFMWNQHLGYVLTCPSNLGTGLRGGVHVKLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EKGGNMKEVFRRFCVGLQKIEEIFKKAGHPFMWNQHLGYVLTCPSNLGTGLRGGVHVKLA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 HLSKHPKFEEILTRLRLQKRGTGGVDTAAVGSVFDVSNADRLGSSEVEQVQLVVDGVKLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HLSKHPKFEEILTRLRLQKRGTGGVDTAAVGSVFDVSNADRLGSSEVEQVQLVVDGVKLM
310 320 330 340 350 360
370 380
pF1KE4 VEMEKKLEKGQSIDDMIPAQK
:::::::::::::::::::::
XP_016 VEMEKKLEKGQSIDDMIPAQK
370 380
>>NP_001815 (OMIM: 123310) creatine kinase M-type [Homo (381 aa)
initn: 2578 init1: 2578 opt: 2578 Z-score: 3141.3 bits: 590.0 E(85289): 3.1e-168
Smith-Waterman score: 2578; 99.7% identity (100.0% similar) in 381 aa overlap (1-381:1-381)
10 20 30 40 50 60
pF1KE4 MPFGNTHNKFKLNYKPEEEYPDLSKHNNHMAKVLTLELYKKLRDKETPSGFTVDDVIQTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPFGNTHNKFKLNYKPEEEYPDLSKHNNHMAKVLTLELYKKLRDKETPSGFTVDDVIQTG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 VDNPGHPFIMTVGCVAGDEESYEVFKELFDPIISDRHGGYKPTDKHKTDLNHENLKGGDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VDNPGHPFIMTVGCVAGDEESYEVFKELFDPIISDRHGGYKPTDKHKTDLNHENLKGGDD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 LDPNYVLSSRVRTGRSIKGYTLPPHCSRGERRAVEKLSVEALNSLTGEFKGKYYPLKSMT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LDPNYVLSSRVRTGRSIKGYTLPPHCSRGERRAVEKLSVEALNSLTGEFKGKYYPLKSMT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 EKEQQQLIDDHFLFDKPVSPLLLASGMARDWPDARGIWHNDNKSLLVWVNEEDHLRVISM
::::::::::::::::::::::::::::::::::::::::::::.:::::::::::::::
NP_001 EKEQQQLIDDHFLFDKPVSPLLLASGMARDWPDARGIWHNDNKSFLVWVNEEDHLRVISM
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 EKGGNMKEVFRRFCVGLQKIEEIFKKAGHPFMWNQHLGYVLTCPSNLGTGLRGGVHVKLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EKGGNMKEVFRRFCVGLQKIEEIFKKAGHPFMWNQHLGYVLTCPSNLGTGLRGGVHVKLA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 HLSKHPKFEEILTRLRLQKRGTGGVDTAAVGSVFDVSNADRLGSSEVEQVQLVVDGVKLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HLSKHPKFEEILTRLRLQKRGTGGVDTAAVGSVFDVSNADRLGSSEVEQVQLVVDGVKLM
310 320 330 340 350 360
370 380
pF1KE4 VEMEKKLEKGQSIDDMIPAQK
:::::::::::::::::::::
NP_001 VEMEKKLEKGQSIDDMIPAQK
370 380
>>NP_001814 (OMIM: 123280) creatine kinase B-type [Homo (381 aa)
initn: 2159 init1: 2159 opt: 2159 Z-score: 2631.0 bits: 495.6 E(85289): 8.2e-140
Smith-Waterman score: 2159; 80.3% identity (92.4% similar) in 381 aa overlap (1-381:1-381)
10 20 30 40 50 60
pF1KE4 MPFGNTHNKFKLNYKPEEEYPDLSKHNNHMAKVLTLELYKKLRDKETPSGFTVDDVIQTG
:::.:.:: .:: . :.:.:::: :::::::::: ::: .:: : ::::::.:::::::
NP_001 MPFSNSHNALKLRFPAEDEFPDLSAHNNHMAKVLTPELYAELRAKSTPSGFTLDDVIQTG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 VDNPGHPFIMTVGCVAGDEESYEVFKELFDPIISDRHGGYKPTDKHKTDLNHENLKGGDD
:::::::.::::::::::::::::::.:::::: ::::::::.:.:::::: .::.::::
NP_001 VDNPGHPYIMTVGCVAGDEESYEVFKDLFDPIIEDRHGGYKPSDEHKTDLNPDNLQGGDD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 LDPNYVLSSRVRTGRSIKGYTLPPHCSRGERRAVEKLSVEALNSLTGEFKGKYYPLKSMT
:::::::::::::::::.:. ::::::::::::.:::.::::.:: :.. :.:: :::::
NP_001 LDPNYVLSSRVRTGRSIRGFCLPPHCSRGERRAIEKLAVEALSSLDGDLAGRYYALKSMT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 EKEQQQLIDDHFLFDKPVSPLLLASGMARDWPDARGIWHNDNKSLLVWVNEEDHLRVISM
: :::::::::::::::::::::::::::::::::::::::::..:::::::::::::::
NP_001 EAEQQQLIDDHFLFDKPVSPLLLASGMARDWPDARGIWHNDNKTFLVWVNEEDHLRVISM
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 EKGGNMKEVFRRFCVGLQKIEEIFKKAGHPFMWNQHLGYVLTCPSNLGTGLRGGVHVKLA
.::::::::: :::.:: .:: .::. . :::: ::::.::::::::::::.:::.::
NP_001 QKGGNMKEVFTRFCTGLTQIETLFKSKDYEFMWNPHLGYILTCPSNLGTGLRAGVHIKLP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 HLSKHPKFEEILTRLRLQKRGTGGVDTAAVGSVFDVSNADRLGSSEVEQVQLVVDGVKLM
.:.:: :: :.: ::::::::::::::::::.::::::::::: :::: ::.:::::::.
NP_001 NLGKHEKFSEVLKRLRLQKRGTGGVDTAAVGGVFDVSNADRLGFSEVELVQMVVDGVKLL
310 320 330 340 350 360
370 380
pF1KE4 VEMEKKLEKGQSIDDMIPAQK
.:::..::.::.:::..::::
NP_001 IEMEQRLEQGQAIDDLMPAQK
370 380
>>NP_001015001 (OMIM: 613415) creatine kinase U-type, mi (417 aa)
initn: 1676 init1: 1623 opt: 1679 Z-score: 2045.9 bits: 387.4 E(85289): 3.2e-107
Smith-Waterman score: 1679; 67.3% identity (85.9% similar) in 361 aa overlap (14-373:47-406)
10 20 30 40
pF1KE4 MPFGNTHNKFKLNYKPEEEYPDLSKHNNHMAKVLTLELYKKLR
: : ::::: :::: ::. :: .: .:
NP_001 LLALAGAGSLAAGFLLRPEPVRAASERRRLYPPSAEYPDLRKHNNCMASHLTPAVYARLC
20 30 40 50 60 70
50 60 70 80 90 100
pF1KE4 DKETPSGFTVDDVIQTGVDNPGHPFIMTVGCVAGDEESYEVFKELFDPIISDRHGGYKP-
:: ::.:.:.:. ::::::::::::: ::: ::::::.:::: .::::.:..::.:: :
NP_001 DKTTPTGWTLDQCIQTGVDNPGHPFIKTVGMVAGDEETYEVFADLFDPVIQERHNGYDPR
80 90 100 110 120 130
110 120 130 140 150 160
pF1KE4 TDKHKTDLNHENLKGGDDLDPNYVLSSRVRTGRSIKGYTLPPHCSRGERRAVEKLSVEAL
: :: :::. ....: .: :::::::::::::.: .::: :.:.::: ::.. :.::
NP_001 TMKHTTDLDASKIRSGY-FDERYVLSSRVRTGRSIRGLSLPPACTRAERREVERVVVDAL
140 150 160 170 180 190
170 180 190 200 210 220
pF1KE4 NSLTGEFKGKYYPLKSMTEKEQQQLIDDHFLFDKPVSPLLLASGMARDWPDARGIWHNDN
..: :.. :.:: :. ::: :::::::::::::::::::: :.:::::::::::::::..
NP_001 SGLKGDLAGRYYRLSEMTEAEQQQLIDDHFLFDKPVSPLLTAAGMARDWPDARGIWHNNE
200 210 220 230 240 250
230 240 250 260 270 280
pF1KE4 KSLLVWVNEEDHLRVISMEKGGNMKEVFRRFCVGLQKIEEIFKKAGHPFMWNQHLGYVLT
::.:.::::::: ::::::::::::.::.::: ::...:..... : ::::..:::.::
NP_001 KSFLIWVNEEDHTRVISMEKGGNMKRVFERFCRGLKEVERLIQERGWEFMWNERLGYILT
260 270 280 290 300 310
290 300 310 320 330 340
pF1KE4 CPSNLGTGLRGGVHVKLAHLSKHPKFEEILTRLRLQKRGTGGVDTAAVGSVFDVSNADRL
::::::::::.:::.:: ::: .: .:: :::::::::::::::.:.:::.:: :::
NP_001 CPSNLGTGLRAGVHIKLPLLSKDSRFPKILENLRLQKRGTGGVDTAATGGVFDISNLDRL
320 330 340 350 360 370
350 360 370 380
pF1KE4 GSSEVEQVQLVVDGVKLMVEMEKKLEKGQSIDDMIPAQK
:.:::: ::::.:::. ... :..::.::.:
NP_001 GKSEVELVQLVIDGVNYLIDCERRLERGQDIRIPTPVIHTKH
380 390 400 410
>>NP_066270 (OMIM: 123290) creatine kinase U-type, mitoc (417 aa)
initn: 1676 init1: 1623 opt: 1679 Z-score: 2045.9 bits: 387.4 E(85289): 3.2e-107
Smith-Waterman score: 1679; 67.3% identity (85.9% similar) in 361 aa overlap (14-373:47-406)
10 20 30 40
pF1KE4 MPFGNTHNKFKLNYKPEEEYPDLSKHNNHMAKVLTLELYKKLR
: : ::::: :::: ::. :: .: .:
NP_066 LLALAGAGSLAAGFLLRPEPVRAASERRRLYPPSAEYPDLRKHNNCMASHLTPAVYARLC
20 30 40 50 60 70
50 60 70 80 90 100
pF1KE4 DKETPSGFTVDDVIQTGVDNPGHPFIMTVGCVAGDEESYEVFKELFDPIISDRHGGYKP-
:: ::.:.:.:. ::::::::::::: ::: ::::::.:::: .::::.:..::.:: :
NP_066 DKTTPTGWTLDQCIQTGVDNPGHPFIKTVGMVAGDEETYEVFADLFDPVIQERHNGYDPR
80 90 100 110 120 130
110 120 130 140 150 160
pF1KE4 TDKHKTDLNHENLKGGDDLDPNYVLSSRVRTGRSIKGYTLPPHCSRGERRAVEKLSVEAL
: :: :::. ....: .: :::::::::::::.: .::: :.:.::: ::.. :.::
NP_066 TMKHTTDLDASKIRSGY-FDERYVLSSRVRTGRSIRGLSLPPACTRAERREVERVVVDAL
140 150 160 170 180 190
170 180 190 200 210 220
pF1KE4 NSLTGEFKGKYYPLKSMTEKEQQQLIDDHFLFDKPVSPLLLASGMARDWPDARGIWHNDN
..: :.. :.:: :. ::: :::::::::::::::::::: :.:::::::::::::::..
NP_066 SGLKGDLAGRYYRLSEMTEAEQQQLIDDHFLFDKPVSPLLTAAGMARDWPDARGIWHNNE
200 210 220 230 240 250
230 240 250 260 270 280
pF1KE4 KSLLVWVNEEDHLRVISMEKGGNMKEVFRRFCVGLQKIEEIFKKAGHPFMWNQHLGYVLT
::.:.::::::: ::::::::::::.::.::: ::...:..... : ::::..:::.::
NP_066 KSFLIWVNEEDHTRVISMEKGGNMKRVFERFCRGLKEVERLIQERGWEFMWNERLGYILT
260 270 280 290 300 310
290 300 310 320 330 340
pF1KE4 CPSNLGTGLRGGVHVKLAHLSKHPKFEEILTRLRLQKRGTGGVDTAAVGSVFDVSNADRL
::::::::::.:::.:: ::: .: .:: :::::::::::::::.:.:::.:: :::
NP_066 CPSNLGTGLRAGVHIKLPLLSKDSRFPKILENLRLQKRGTGGVDTAATGGVFDISNLDRL
320 330 340 350 360 370
350 360 370 380
pF1KE4 GSSEVEQVQLVVDGVKLMVEMEKKLEKGQSIDDMIPAQK
:.:::: ::::.:::. ... :..::.::.:
NP_066 GKSEVELVQLVIDGVNYLIDCERRLERGQDIRIPTPVIHTKH
380 390 400 410
>>XP_011519499 (OMIM: 123290) PREDICTED: creatine kinase (417 aa)
initn: 1676 init1: 1623 opt: 1679 Z-score: 2045.9 bits: 387.4 E(85289): 3.2e-107
Smith-Waterman score: 1679; 67.3% identity (85.9% similar) in 361 aa overlap (14-373:47-406)
10 20 30 40
pF1KE4 MPFGNTHNKFKLNYKPEEEYPDLSKHNNHMAKVLTLELYKKLR
: : ::::: :::: ::. :: .: .:
XP_011 LLALAGAGSLAAGFLLRPEPVRAASERRRLYPPSAEYPDLRKHNNCMASHLTPAVYARLC
20 30 40 50 60 70
50 60 70 80 90 100
pF1KE4 DKETPSGFTVDDVIQTGVDNPGHPFIMTVGCVAGDEESYEVFKELFDPIISDRHGGYKP-
:: ::.:.:.:. ::::::::::::: ::: ::::::.:::: .::::.:..::.:: :
XP_011 DKTTPTGWTLDQCIQTGVDNPGHPFIKTVGMVAGDEETYEVFADLFDPVIQERHNGYDPR
80 90 100 110 120 130
110 120 130 140 150 160
pF1KE4 TDKHKTDLNHENLKGGDDLDPNYVLSSRVRTGRSIKGYTLPPHCSRGERRAVEKLSVEAL
: :: :::. ....: .: :::::::::::::.: .::: :.:.::: ::.. :.::
XP_011 TMKHTTDLDASKIRSGY-FDERYVLSSRVRTGRSIRGLSLPPACTRAERREVERVVVDAL
140 150 160 170 180 190
170 180 190 200 210 220
pF1KE4 NSLTGEFKGKYYPLKSMTEKEQQQLIDDHFLFDKPVSPLLLASGMARDWPDARGIWHNDN
..: :.. :.:: :. ::: :::::::::::::::::::: :.:::::::::::::::..
XP_011 SGLKGDLAGRYYRLSEMTEAEQQQLIDDHFLFDKPVSPLLTAAGMARDWPDARGIWHNNE
200 210 220 230 240 250
230 240 250 260 270 280
pF1KE4 KSLLVWVNEEDHLRVISMEKGGNMKEVFRRFCVGLQKIEEIFKKAGHPFMWNQHLGYVLT
::.:.::::::: ::::::::::::.::.::: ::...:..... : ::::..:::.::
XP_011 KSFLIWVNEEDHTRVISMEKGGNMKRVFERFCRGLKEVERLIQERGWEFMWNERLGYILT
260 270 280 290 300 310
290 300 310 320 330 340
pF1KE4 CPSNLGTGLRGGVHVKLAHLSKHPKFEEILTRLRLQKRGTGGVDTAAVGSVFDVSNADRL
::::::::::.:::.:: ::: .: .:: :::::::::::::::.:.:::.:: :::
XP_011 CPSNLGTGLRAGVHIKLPLLSKDSRFPKILENLRLQKRGTGGVDTAATGGVFDISNLDRL
320 330 340 350 360 370
350 360 370 380
pF1KE4 GSSEVEQVQLVVDGVKLMVEMEKKLEKGQSIDDMIPAQK
:.:::: ::::.:::. ... :..::.::.:
XP_011 GKSEVELVQLVIDGVNYLIDCERRLERGQDIRIPTPVIHTKH
380 390 400 410
>>NP_001308855 (OMIM: 613415) creatine kinase U-type, mi (417 aa)
initn: 1676 init1: 1623 opt: 1679 Z-score: 2045.9 bits: 387.4 E(85289): 3.2e-107
Smith-Waterman score: 1679; 67.3% identity (85.9% similar) in 361 aa overlap (14-373:47-406)
10 20 30 40
pF1KE4 MPFGNTHNKFKLNYKPEEEYPDLSKHNNHMAKVLTLELYKKLR
: : ::::: :::: ::. :: .: .:
NP_001 LLALAGAGSLAAGFLLRPEPVRAASERRRLYPPSAEYPDLRKHNNCMASHLTPAVYARLC
20 30 40 50 60 70
50 60 70 80 90 100
pF1KE4 DKETPSGFTVDDVIQTGVDNPGHPFIMTVGCVAGDEESYEVFKELFDPIISDRHGGYKP-
:: ::.:.:.:. ::::::::::::: ::: ::::::.:::: .::::.:..::.:: :
NP_001 DKTTPTGWTLDQCIQTGVDNPGHPFIKTVGMVAGDEETYEVFADLFDPVIQERHNGYDPR
80 90 100 110 120 130
110 120 130 140 150 160
pF1KE4 TDKHKTDLNHENLKGGDDLDPNYVLSSRVRTGRSIKGYTLPPHCSRGERRAVEKLSVEAL
: :: :::. ....: .: :::::::::::::.: .::: :.:.::: ::.. :.::
NP_001 TMKHTTDLDASKIRSGY-FDERYVLSSRVRTGRSIRGLSLPPACTRAERREVERVVVDAL
140 150 160 170 180 190
170 180 190 200 210 220
pF1KE4 NSLTGEFKGKYYPLKSMTEKEQQQLIDDHFLFDKPVSPLLLASGMARDWPDARGIWHNDN
..: :.. :.:: :. ::: :::::::::::::::::::: :.:::::::::::::::..
NP_001 SGLKGDLAGRYYRLSEMTEAEQQQLIDDHFLFDKPVSPLLTAAGMARDWPDARGIWHNNE
200 210 220 230 240 250
230 240 250 260 270 280
pF1KE4 KSLLVWVNEEDHLRVISMEKGGNMKEVFRRFCVGLQKIEEIFKKAGHPFMWNQHLGYVLT
::.:.::::::: ::::::::::::.::.::: ::...:..... : ::::..:::.::
NP_001 KSFLIWVNEEDHTRVISMEKGGNMKRVFERFCRGLKEVERLIQERGWEFMWNERLGYILT
260 270 280 290 300 310
290 300 310 320 330 340
pF1KE4 CPSNLGTGLRGGVHVKLAHLSKHPKFEEILTRLRLQKRGTGGVDTAAVGSVFDVSNADRL
::::::::::.:::.:: ::: .: .:: :::::::::::::::.:.:::.:: :::
NP_001 CPSNLGTGLRAGVHIKLPLLSKDSRFPKILENLRLQKRGTGGVDTAATGGVFDISNLDRL
320 330 340 350 360 370
350 360 370 380
pF1KE4 GSSEVEQVQLVVDGVKLMVEMEKKLEKGQSIDDMIPAQK
:.:::: ::::.:::. ... :..::.::.:
NP_001 GKSEVELVQLVIDGVNYLIDCERRLERGQDIRIPTPVIHTKH
380 390 400 410
>>XP_011519500 (OMIM: 123290) PREDICTED: creatine kinase (376 aa)
initn: 1676 init1: 1623 opt: 1672 Z-score: 2038.1 bits: 385.8 E(85289): 8.8e-107
Smith-Waterman score: 1672; 67.4% identity (86.1% similar) in 359 aa overlap (16-373:8-365)
10 20 30 40 50 60
pF1KE4 MPFGNTHNKFKLNYKPEEEYPDLSKHNNHMAKVLTLELYKKLRDKETPSGFTVDDVIQTG
: ::::: :::: ::. :: .: .: :: ::.:.:.:. ::::
XP_011 MVTGYPLPSAEYPDLRKHNNCMASHLTPAVYARLCDKTTPTGWTLDQCIQTG
10 20 30 40 50
70 80 90 100 110
pF1KE4 VDNPGHPFIMTVGCVAGDEESYEVFKELFDPIISDRHGGYKP-TDKHKTDLNHENLKGGD
::::::::: ::: ::::::.:::: .::::.:..::.:: : : :: :::. ....:
XP_011 VDNPGHPFIKTVGMVAGDEETYEVFADLFDPVIQERHNGYDPRTMKHTTDLDASKIRSGY
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE4 DLDPNYVLSSRVRTGRSIKGYTLPPHCSRGERRAVEKLSVEALNSLTGEFKGKYYPLKSM
.: :::::::::::::.: .::: :.:.::: ::.. :.::..: :.. :.:: :. :
XP_011 -FDERYVLSSRVRTGRSIRGLSLPPACTRAERREVERVVVDALSGLKGDLAGRYYRLSEM
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE4 TEKEQQQLIDDHFLFDKPVSPLLLASGMARDWPDARGIWHNDNKSLLVWVNEEDHLRVIS
:: :::::::::::::::::::: :.:::::::::::::::..::.:.::::::: ::::
XP_011 TEAEQQQLIDDHFLFDKPVSPLLTAAGMARDWPDARGIWHNNEKSFLIWVNEEDHTRVIS
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE4 MEKGGNMKEVFRRFCVGLQKIEEIFKKAGHPFMWNQHLGYVLTCPSNLGTGLRGGVHVKL
::::::::.::.::: ::...:..... : ::::..:::.::::::::::::.:::.::
XP_011 MEKGGNMKRVFERFCRGLKEVERLIQERGWEFMWNERLGYILTCPSNLGTGLRAGVHIKL
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE4 AHLSKHPKFEEILTRLRLQKRGTGGVDTAAVGSVFDVSNADRLGSSEVEQVQLVVDGVKL
::: .: .:: :::::::::::::::.:.:::.:: ::::.:::: ::::.:::.
XP_011 PLLSKDSRFPKILENLRLQKRGTGGVDTAATGGVFDISNLDRLGKSEVELVQLVIDGVNY
300 310 320 330 340 350
360 370 380
pF1KE4 MVEMEKKLEKGQSIDDMIPAQK
... :..::.::.:
XP_011 LIDCERRLERGQDIRIPTPVIHTKH
360 370
>>NP_001308856 (OMIM: 613415) creatine kinase U-type, mi (448 aa)
initn: 1676 init1: 1623 opt: 1672 Z-score: 2036.9 bits: 385.9 E(85289): 1e-106
Smith-Waterman score: 1672; 67.4% identity (86.1% similar) in 359 aa overlap (16-373:80-437)
10 20 30 40
pF1KE4 MPFGNTHNKFKLNYKPEEEYPDLSKHNNHMAKVLTLELYKKLRDK
: ::::: :::: ::. :: .: .: ::
NP_001 SQTWPTGQLPGNCTRSRRLCPPSMVTGYPLPSAEYPDLRKHNNCMASHLTPAVYARLCDK
50 60 70 80 90 100
50 60 70 80 90 100
pF1KE4 ETPSGFTVDDVIQTGVDNPGHPFIMTVGCVAGDEESYEVFKELFDPIISDRHGGYKP-TD
::.:.:.:. ::::::::::::: ::: ::::::.:::: .::::.:..::.:: : :
NP_001 TTPTGWTLDQCIQTGVDNPGHPFIKTVGMVAGDEETYEVFADLFDPVIQERHNGYDPRTM
110 120 130 140 150 160
110 120 130 140 150 160
pF1KE4 KHKTDLNHENLKGGDDLDPNYVLSSRVRTGRSIKGYTLPPHCSRGERRAVEKLSVEALNS
:: :::. ....: .: :::::::::::::.: .::: :.:.::: ::.. :.::..
NP_001 KHTTDLDASKIRSGY-FDERYVLSSRVRTGRSIRGLSLPPACTRAERREVERVVVDALSG
170 180 190 200 210 220
170 180 190 200 210 220
pF1KE4 LTGEFKGKYYPLKSMTEKEQQQLIDDHFLFDKPVSPLLLASGMARDWPDARGIWHNDNKS
: :.. :.:: :. ::: :::::::::::::::::::: :.:::::::::::::::..::
NP_001 LKGDLAGRYYRLSEMTEAEQQQLIDDHFLFDKPVSPLLTAAGMARDWPDARGIWHNNEKS
230 240 250 260 270 280
230 240 250 260 270 280
pF1KE4 LLVWVNEEDHLRVISMEKGGNMKEVFRRFCVGLQKIEEIFKKAGHPFMWNQHLGYVLTCP
.:.::::::: ::::::::::::.::.::: ::...:..... : ::::..:::.::::
NP_001 FLIWVNEEDHTRVISMEKGGNMKRVFERFCRGLKEVERLIQERGWEFMWNERLGYILTCP
290 300 310 320 330 340
290 300 310 320 330 340
pF1KE4 SNLGTGLRGGVHVKLAHLSKHPKFEEILTRLRLQKRGTGGVDTAAVGSVFDVSNADRLGS
::::::::.:::.:: ::: .: .:: :::::::::::::::.:.:::.:: ::::.
NP_001 SNLGTGLRAGVHIKLPLLSKDSRFPKILENLRLQKRGTGGVDTAATGGVFDISNLDRLGK
350 360 370 380 390 400
350 360 370 380
pF1KE4 SEVEQVQLVVDGVKLMVEMEKKLEKGQSIDDMIPAQK
:::: ::::.:::. ... :..::.::.:
NP_001 SEVELVQLVIDGVNYLIDCERRLERGQDIRIPTPVIHTKH
410 420 430 440
>>XP_016877858 (OMIM: 613415) PREDICTED: creatine kinase (448 aa)
initn: 1676 init1: 1623 opt: 1672 Z-score: 2036.9 bits: 385.9 E(85289): 1e-106
Smith-Waterman score: 1672; 67.4% identity (86.1% similar) in 359 aa overlap (16-373:80-437)
10 20 30 40
pF1KE4 MPFGNTHNKFKLNYKPEEEYPDLSKHNNHMAKVLTLELYKKLRDK
: ::::: :::: ::. :: .: .: ::
XP_016 SQTWPTGQLPGNCTRSRRLCPPSMVTGYPLPSAEYPDLRKHNNCMASHLTPAVYARLCDK
50 60 70 80 90 100
50 60 70 80 90 100
pF1KE4 ETPSGFTVDDVIQTGVDNPGHPFIMTVGCVAGDEESYEVFKELFDPIISDRHGGYKP-TD
::.:.:.:. ::::::::::::: ::: ::::::.:::: .::::.:..::.:: : :
XP_016 TTPTGWTLDQCIQTGVDNPGHPFIKTVGMVAGDEETYEVFADLFDPVIQERHNGYDPRTM
110 120 130 140 150 160
110 120 130 140 150 160
pF1KE4 KHKTDLNHENLKGGDDLDPNYVLSSRVRTGRSIKGYTLPPHCSRGERRAVEKLSVEALNS
:: :::. ....: .: :::::::::::::.: .::: :.:.::: ::.. :.::..
XP_016 KHTTDLDASKIRSGY-FDERYVLSSRVRTGRSIRGLSLPPACTRAERREVERVVVDALSG
170 180 190 200 210 220
170 180 190 200 210 220
pF1KE4 LTGEFKGKYYPLKSMTEKEQQQLIDDHFLFDKPVSPLLLASGMARDWPDARGIWHNDNKS
: :.. :.:: :. ::: :::::::::::::::::::: :.:::::::::::::::..::
XP_016 LKGDLAGRYYRLSEMTEAEQQQLIDDHFLFDKPVSPLLTAAGMARDWPDARGIWHNNEKS
230 240 250 260 270 280
230 240 250 260 270 280
pF1KE4 LLVWVNEEDHLRVISMEKGGNMKEVFRRFCVGLQKIEEIFKKAGHPFMWNQHLGYVLTCP
.:.::::::: ::::::::::::.::.::: ::...:..... : ::::..:::.::::
XP_016 FLIWVNEEDHTRVISMEKGGNMKRVFERFCRGLKEVERLIQERGWEFMWNERLGYILTCP
290 300 310 320 330 340
290 300 310 320 330 340
pF1KE4 SNLGTGLRGGVHVKLAHLSKHPKFEEILTRLRLQKRGTGGVDTAAVGSVFDVSNADRLGS
::::::::.:::.:: ::: .: .:: :::::::::::::::.:.:::.:: ::::.
XP_016 SNLGTGLRAGVHIKLPLLSKDSRFPKILENLRLQKRGTGGVDTAATGGVFDISNLDRLGK
350 360 370 380 390 400
350 360 370 380
pF1KE4 SEVEQVQLVVDGVKLMVEMEKKLEKGQSIDDMIPAQK
:::: ::::.:::. ... :..::.::.:
XP_016 SEVELVQLVIDGVNYLIDCERRLERGQDIRIPTPVIHTKH
410 420 430 440
381 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 02:04:01 2016 done: Sun Nov 6 02:04:02 2016
Total Scan time: 8.310 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]