Result of FASTA (omim) for
pFN21AE4352
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE4352, 369 aa
1>>>pF1KE4352 369 - 369 aa - 369 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.3467+/-0.00042; mu= 15.5065+/- 0.026
mean_var=56.0151+/-11.275, 0's: 0 Z-trim(109.5): 42 B-trim: 0 in 0/54
Lambda= 0.171365
statistics sampled from 17690 (17697) to 17690 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.581), E-opt: 0.2 (0.207), width: 16
Scan time: 7.760
The best scores are: opt bits E(85289)
XP_011526072 (OMIM: 600944) PREDICTED: deoxyhypusi ( 369) 2437 611.0 1.4e-174
NP_001921 (OMIM: 600944) deoxyhypusine synthase is ( 369) 2437 611.0 1.4e-174
NP_001193903 (OMIM: 600944) deoxyhypusine synthase ( 327) 2001 503.2 3.4e-142
NP_037538 (OMIM: 600944) deoxyhypusine synthase is ( 322) 1727 435.5 8.3e-122
XP_011526073 (OMIM: 600944) PREDICTED: deoxyhypusi ( 186) 1243 315.7 5.3e-86
>>XP_011526072 (OMIM: 600944) PREDICTED: deoxyhypusine s (369 aa)
initn: 2437 init1: 2437 opt: 2437 Z-score: 3255.5 bits: 611.0 E(85289): 1.4e-174
Smith-Waterman score: 2437; 100.0% identity (100.0% similar) in 369 aa overlap (1-369:1-369)
10 20 30 40 50 60
pF1KE4 MEGSLEREAPAGALAAVLKHSSTLPPESTQVRGYDFNRGVNYRALLEAFGTTGFQATNFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MEGSLEREAPAGALAAVLKHSSTLPPESTQVRGYDFNRGVNYRALLEAFGTTGFQATNFG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 RAVQQVNAMIEKKLEPLSQDEDQHADLTQSRRPLTSCTIFLGYTSNLISSGIRETIRYLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RAVQQVNAMIEKKLEPLSQDEDQHADLTQSRRPLTSCTIFLGYTSNLISSGIRETIRYLV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 QHNMVDVLVTTAGGVEEDLIKCLAPTYLGEFSLRGKELRENGINRIGNLLVPNENYCKFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QHNMVDVLVTTAGGVEEDLIKCLAPTYLGEFSLRGKELRENGINRIGNLLVPNENYCKFE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 DWLMPILDQMVMEQNTEGVKWTPSKMIARLGKEINNPESVYYWAQKNHIPVFSPALTDGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DWLMPILDQMVMEQNTEGVKWTPSKMIARLGKEINNPESVYYWAQKNHIPVFSPALTDGS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 LGDMIFFHSYKNPGLVLDIVEDLRLINTQAIFAKCTGMIILGGGVVKHHIANANLMRNGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LGDMIFFHSYKNPGLVLDIVEDLRLINTQAIFAKCTGMIILGGGVVKHHIANANLMRNGA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 DYAVYINTAQEFDGSDSGARPDEAVSWGKIRVDAQPVKVYADASLVFPLLVAETFAQKMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DYAVYINTAQEFDGSDSGARPDEAVSWGKIRVDAQPVKVYADASLVFPLLVAETFAQKMD
310 320 330 340 350 360
pF1KE4 AFMHEKNED
:::::::::
XP_011 AFMHEKNED
>>NP_001921 (OMIM: 600944) deoxyhypusine synthase isofor (369 aa)
initn: 2437 init1: 2437 opt: 2437 Z-score: 3255.5 bits: 611.0 E(85289): 1.4e-174
Smith-Waterman score: 2437; 100.0% identity (100.0% similar) in 369 aa overlap (1-369:1-369)
10 20 30 40 50 60
pF1KE4 MEGSLEREAPAGALAAVLKHSSTLPPESTQVRGYDFNRGVNYRALLEAFGTTGFQATNFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEGSLEREAPAGALAAVLKHSSTLPPESTQVRGYDFNRGVNYRALLEAFGTTGFQATNFG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 RAVQQVNAMIEKKLEPLSQDEDQHADLTQSRRPLTSCTIFLGYTSNLISSGIRETIRYLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RAVQQVNAMIEKKLEPLSQDEDQHADLTQSRRPLTSCTIFLGYTSNLISSGIRETIRYLV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 QHNMVDVLVTTAGGVEEDLIKCLAPTYLGEFSLRGKELRENGINRIGNLLVPNENYCKFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QHNMVDVLVTTAGGVEEDLIKCLAPTYLGEFSLRGKELRENGINRIGNLLVPNENYCKFE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 DWLMPILDQMVMEQNTEGVKWTPSKMIARLGKEINNPESVYYWAQKNHIPVFSPALTDGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DWLMPILDQMVMEQNTEGVKWTPSKMIARLGKEINNPESVYYWAQKNHIPVFSPALTDGS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 LGDMIFFHSYKNPGLVLDIVEDLRLINTQAIFAKCTGMIILGGGVVKHHIANANLMRNGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LGDMIFFHSYKNPGLVLDIVEDLRLINTQAIFAKCTGMIILGGGVVKHHIANANLMRNGA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 DYAVYINTAQEFDGSDSGARPDEAVSWGKIRVDAQPVKVYADASLVFPLLVAETFAQKMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DYAVYINTAQEFDGSDSGARPDEAVSWGKIRVDAQPVKVYADASLVFPLLVAETFAQKMD
310 320 330 340 350 360
pF1KE4 AFMHEKNED
:::::::::
NP_001 AFMHEKNED
>>NP_001193903 (OMIM: 600944) deoxyhypusine synthase iso (327 aa)
initn: 2001 init1: 2001 opt: 2001 Z-score: 2673.8 bits: 503.2 E(85289): 3.4e-142
Smith-Waterman score: 2001; 100.0% identity (100.0% similar) in 301 aa overlap (69-369:27-327)
40 50 60 70 80 90
pF1KE4 GVNYRALLEAFGTTGFQATNFGRAVQQVNAMIEKKLEPLSQDEDQHADLTQSRRPLTSCT
::::::::::::::::::::::::::::::
NP_001 MPIIPAFWEAEAGGSREEEFETSLANMIEKKLEPLSQDEDQHADLTQSRRPLTSCT
10 20 30 40 50
100 110 120 130 140 150
pF1KE4 IFLGYTSNLISSGIRETIRYLVQHNMVDVLVTTAGGVEEDLIKCLAPTYLGEFSLRGKEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IFLGYTSNLISSGIRETIRYLVQHNMVDVLVTTAGGVEEDLIKCLAPTYLGEFSLRGKEL
60 70 80 90 100 110
160 170 180 190 200 210
pF1KE4 RENGINRIGNLLVPNENYCKFEDWLMPILDQMVMEQNTEGVKWTPSKMIARLGKEINNPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RENGINRIGNLLVPNENYCKFEDWLMPILDQMVMEQNTEGVKWTPSKMIARLGKEINNPE
120 130 140 150 160 170
220 230 240 250 260 270
pF1KE4 SVYYWAQKNHIPVFSPALTDGSLGDMIFFHSYKNPGLVLDIVEDLRLINTQAIFAKCTGM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SVYYWAQKNHIPVFSPALTDGSLGDMIFFHSYKNPGLVLDIVEDLRLINTQAIFAKCTGM
180 190 200 210 220 230
280 290 300 310 320 330
pF1KE4 IILGGGVVKHHIANANLMRNGADYAVYINTAQEFDGSDSGARPDEAVSWGKIRVDAQPVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IILGGGVVKHHIANANLMRNGADYAVYINTAQEFDGSDSGARPDEAVSWGKIRVDAQPVK
240 250 260 270 280 290
340 350 360
pF1KE4 VYADASLVFPLLVAETFAQKMDAFMHEKNED
:::::::::::::::::::::::::::::::
NP_001 VYADASLVFPLLVAETFAQKMDAFMHEKNED
300 310 320
>>NP_037538 (OMIM: 600944) deoxyhypusine synthase isofor (322 aa)
initn: 1727 init1: 1727 opt: 1727 Z-score: 2307.8 bits: 435.5 E(85289): 8.3e-122
Smith-Waterman score: 2028; 87.3% identity (87.3% similar) in 369 aa overlap (1-369:1-322)
10 20 30 40 50 60
pF1KE4 MEGSLEREAPAGALAAVLKHSSTLPPESTQVRGYDFNRGVNYRALLEAFGTTGFQATNFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 MEGSLEREAPAGALAAVLKHSSTLPPESTQVRGYDFNRGVNYRALLEAFGTTGFQATNFG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 RAVQQVNAMIEKKLEPLSQDEDQHADLTQSRRPLTSCTIFLGYTSNLISSGIRETIRYLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 RAVQQVNAMIEKKLEPLSQDEDQHADLTQSRRPLTSCTIFLGYTSNLISSGIRETIRYLV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 QHNMVDVLVTTAGGVEEDLIKCLAPTYLGEFSLRGKELRENGINRIGNLLVPNENYCKFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 QHNMVDVLVTTAGGVEEDLIKCLAPTYLGEFSLRGKELRENGINRIGNLLVPNENYCKFE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 DWLMPILDQMVMEQNTEGVKWTPSKMIARLGKEINNPESVYYWAQKNHIPVFSPALTDGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 DWLMPILDQMVMEQNTEGVKWTPSKMIARLGKEINNPESVYYWAQKNHIPVFSPALTDGS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 LGDMIFFHSYKNPGLVLDIVEDLRLINTQAIFAKCTGMIILGGGVVKHHIANANLMRNGA
:::::::::::::::::::::
NP_037 LGDMIFFHSYKNPGLVLDIVE---------------------------------------
250 260
310 320 330 340 350 360
pF1KE4 DYAVYINTAQEFDGSDSGARPDEAVSWGKIRVDAQPVKVYADASLVFPLLVAETFAQKMD
::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 --------AQEFDGSDSGARPDEAVSWGKIRVDAQPVKVYADASLVFPLLVAETFAQKMD
270 280 290 300 310
pF1KE4 AFMHEKNED
:::::::::
NP_037 AFMHEKNED
320
>>XP_011526073 (OMIM: 600944) PREDICTED: deoxyhypusine s (186 aa)
initn: 1243 init1: 1243 opt: 1243 Z-score: 1665.0 bits: 315.7 E(85289): 5.3e-86
Smith-Waterman score: 1243; 100.0% identity (100.0% similar) in 186 aa overlap (184-369:1-186)
160 170 180 190 200 210
pF1KE4 RGKELRENGINRIGNLLVPNENYCKFEDWLMPILDQMVMEQNTEGVKWTPSKMIARLGKE
::::::::::::::::::::::::::::::
XP_011 MPILDQMVMEQNTEGVKWTPSKMIARLGKE
10 20 30
220 230 240 250 260 270
pF1KE4 INNPESVYYWAQKNHIPVFSPALTDGSLGDMIFFHSYKNPGLVLDIVEDLRLINTQAIFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 INNPESVYYWAQKNHIPVFSPALTDGSLGDMIFFHSYKNPGLVLDIVEDLRLINTQAIFA
40 50 60 70 80 90
280 290 300 310 320 330
pF1KE4 KCTGMIILGGGVVKHHIANANLMRNGADYAVYINTAQEFDGSDSGARPDEAVSWGKIRVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KCTGMIILGGGVVKHHIANANLMRNGADYAVYINTAQEFDGSDSGARPDEAVSWGKIRVD
100 110 120 130 140 150
340 350 360
pF1KE4 AQPVKVYADASLVFPLLVAETFAQKMDAFMHEKNED
::::::::::::::::::::::::::::::::::::
XP_011 AQPVKVYADASLVFPLLVAETFAQKMDAFMHEKNED
160 170 180
369 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 02:07:15 2016 done: Sun Nov 6 02:07:17 2016
Total Scan time: 7.760 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]