Result of FASTA (omim) for
pFN21AE4334
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE4334, 344 aa
1>>>pF1KE4334 344 - 344 aa - 344 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.6587+/-0.000368; mu= 10.4652+/- 0.023
mean_var=149.4760+/-29.888, 0's: 0 Z-trim(118.2): 113 B-trim: 129 in 1/52
Lambda= 0.104903
statistics sampled from 30825 (30973) to 30825 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.708), E-opt: 0.2 (0.363), width: 16
Scan time: 8.190
The best scores are: opt bits E(85289)
NP_037541 (OMIM: 136470) follistatin isoform FST34 ( 344) 2503 390.5 2.9e-108
XP_005248458 (OMIM: 136470) PREDICTED: follistatin ( 343) 2480 387.0 3.2e-107
NP_006341 (OMIM: 136470) follistatin isoform FST31 ( 317) 2325 363.5 3.5e-100
XP_005248460 (OMIM: 136470) PREDICTED: follistatin ( 316) 2302 360.0 3.9e-99
XP_005248459 (OMIM: 136470) PREDICTED: follistatin ( 330) 1788 282.3 1e-75
XP_016864443 (OMIM: 136470) PREDICTED: follistatin ( 337) 1788 282.3 1.1e-75
XP_005248457 (OMIM: 136470) PREDICTED: follistatin ( 357) 1788 282.3 1.1e-75
XP_011541401 (OMIM: 136470) PREDICTED: follistatin ( 352) 1593 252.8 8.3e-67
XP_016864444 (OMIM: 136470) PREDICTED: follistatin ( 279) 1233 198.2 1.8e-50
NP_005851 (OMIM: 605343) follistatin-related prote ( 263) 817 135.2 1.5e-31
XP_011539731 (OMIM: 103320,615120) PREDICTED: agri (2004) 428 77.2 3.3e-13
NP_940978 (OMIM: 103320,615120) agrin isoform 2 pr (2045) 428 77.2 3.4e-13
XP_005244806 (OMIM: 103320,615120) PREDICTED: agri (2049) 428 77.2 3.4e-13
NP_001292204 (OMIM: 103320,615120) agrin isoform 1 (2068) 428 77.2 3.4e-13
NP_009016 (OMIM: 605547) follistatin-related prote ( 308) 249 49.3 1.3e-05
XP_016859229 (OMIM: 605734) PREDICTED: tomoregulin ( 266) 202 42.1 0.0016
NP_003683 (OMIM: 603421) tomoregulin-1 precursor [ ( 380) 204 42.6 0.0017
NP_001292063 (OMIM: 605734) tomoregulin-2 isoform ( 346) 202 42.3 0.0019
NP_057276 (OMIM: 605734) tomoregulin-2 isoform 1 p ( 374) 202 42.3 0.002
>>NP_037541 (OMIM: 136470) follistatin isoform FST344 pr (344 aa)
initn: 2503 init1: 2503 opt: 2503 Z-score: 2064.8 bits: 390.5 E(85289): 2.9e-108
Smith-Waterman score: 2503; 100.0% identity (100.0% similar) in 344 aa overlap (1-344:1-344)
10 20 30 40 50 60
pF1KE4 MVRARHQPGGLCLLLLLLCQFMEDRSAQAGNCWLRQAKNGRCQVLYKTELSKEECCSTGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 MVRARHQPGGLCLLLLLLCQFMEDRSAQAGNCWLRQAKNGRCQVLYKTELSKEECCSTGR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 LSTSWTEEDVNDNTLFKWMIFNGGAPNCIPCKETCENVDCGPGKKCRMNKKNKPRCVCAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 LSTSWTEEDVNDNTLFKWMIFNGGAPNCIPCKETCENVDCGPGKKCRMNKKNKPRCVCAP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 DCSNITWKGPVCGLDGKTYRNECALLKARCKEQPELEVQYQGRCKKTCRDVFCPGSSTCV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 DCSNITWKGPVCGLDGKTYRNECALLKARCKEQPELEVQYQGRCKKTCRDVFCPGSSTCV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 VDQTNNAYCVTCNRICPEPASSEQYLCGNDGVTYSSACHLRKATCLLGRSIGLAYEGKCI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 VDQTNNAYCVTCNRICPEPASSEQYLCGNDGVTYSSACHLRKATCLLGRSIGLAYEGKCI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 KAKSCEDIQCTGGKKCLWDFKVGRGRCSLCDELCPDSKSDEPVCASDNATYASECAMKEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 KAKSCEDIQCTGGKKCLWDFKVGRGRCSLCDELCPDSKSDEPVCASDNATYASECAMKEA
250 260 270 280 290 300
310 320 330 340
pF1KE4 ACSSGVLLEVKHSGSCNSISEDTEEEEEDEDQDYSFPISSILEW
::::::::::::::::::::::::::::::::::::::::::::
NP_037 ACSSGVLLEVKHSGSCNSISEDTEEEEEDEDQDYSFPISSILEW
310 320 330 340
>>XP_005248458 (OMIM: 136470) PREDICTED: follistatin iso (343 aa)
initn: 2478 init1: 1767 opt: 2480 Z-score: 2046.0 bits: 387.0 E(85289): 3.2e-107
Smith-Waterman score: 2480; 99.4% identity (99.7% similar) in 344 aa overlap (1-344:1-343)
10 20 30 40 50 60
pF1KE4 MVRARHQPGGLCLLLLLLCQFMEDRSAQAGNCWLRQAKNGRCQVLYKTELSKEECCSTGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MVRARHQPGGLCLLLLLLCQFMEDRSAQAGNCWLRQAKNGRCQVLYKTELSKEECCSTGR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 LSTSWTEEDVNDNTLFKWMIFNGGAPNCIPCKETCENVDCGPGKKCRMNKKNKPRCVCAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LSTSWTEEDVNDNTLFKWMIFNGGAPNCIPCKETCENVDCGPGKKCRMNKKNKPRCVCAP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 DCSNITWKGPVCGLDGKTYRNECALLKARCKEQPELEVQYQGRCKKTCRDVFCPGSSTCV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DCSNITWKGPVCGLDGKTYRNECALLKARCKEQPELEVQYQGRCKKTCRDVFCPGSSTCV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 VDQTNNAYCVTCNRICPEPASSEQYLCGNDGVTYSSACHLRKATCLLGRSIGLAYEGKCI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VDQTNNAYCVTCNRICPEPASSEQYLCGNDGVTYSSACHLRKATCLLGRSIGLAYEGKCI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 KAKSCEDIQCTGGKKCLWDFKVGRGRCSLCDELCPDSKSDEPVCASDNATYASECAMKEA
.::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 -TKSCEDIQCTGGKKCLWDFKVGRGRCSLCDELCPDSKSDEPVCASDNATYASECAMKEA
250 260 270 280 290
310 320 330 340
pF1KE4 ACSSGVLLEVKHSGSCNSISEDTEEEEEDEDQDYSFPISSILEW
::::::::::::::::::::::::::::::::::::::::::::
XP_005 ACSSGVLLEVKHSGSCNSISEDTEEEEEDEDQDYSFPISSILEW
300 310 320 330 340
>>NP_006341 (OMIM: 136470) follistatin isoform FST317 pr (317 aa)
initn: 2325 init1: 2325 opt: 2325 Z-score: 1919.7 bits: 363.5 E(85289): 3.5e-100
Smith-Waterman score: 2325; 100.0% identity (100.0% similar) in 317 aa overlap (1-317:1-317)
10 20 30 40 50 60
pF1KE4 MVRARHQPGGLCLLLLLLCQFMEDRSAQAGNCWLRQAKNGRCQVLYKTELSKEECCSTGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MVRARHQPGGLCLLLLLLCQFMEDRSAQAGNCWLRQAKNGRCQVLYKTELSKEECCSTGR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 LSTSWTEEDVNDNTLFKWMIFNGGAPNCIPCKETCENVDCGPGKKCRMNKKNKPRCVCAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 LSTSWTEEDVNDNTLFKWMIFNGGAPNCIPCKETCENVDCGPGKKCRMNKKNKPRCVCAP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 DCSNITWKGPVCGLDGKTYRNECALLKARCKEQPELEVQYQGRCKKTCRDVFCPGSSTCV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 DCSNITWKGPVCGLDGKTYRNECALLKARCKEQPELEVQYQGRCKKTCRDVFCPGSSTCV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 VDQTNNAYCVTCNRICPEPASSEQYLCGNDGVTYSSACHLRKATCLLGRSIGLAYEGKCI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 VDQTNNAYCVTCNRICPEPASSEQYLCGNDGVTYSSACHLRKATCLLGRSIGLAYEGKCI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 KAKSCEDIQCTGGKKCLWDFKVGRGRCSLCDELCPDSKSDEPVCASDNATYASECAMKEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 KAKSCEDIQCTGGKKCLWDFKVGRGRCSLCDELCPDSKSDEPVCASDNATYASECAMKEA
250 260 270 280 290 300
310 320 330 340
pF1KE4 ACSSGVLLEVKHSGSCNSISEDTEEEEEDEDQDYSFPISSILEW
:::::::::::::::::
NP_006 ACSSGVLLEVKHSGSCN
310
>>XP_005248460 (OMIM: 136470) PREDICTED: follistatin iso (316 aa)
initn: 2300 init1: 1767 opt: 2302 Z-score: 1900.9 bits: 360.0 E(85289): 3.9e-99
Smith-Waterman score: 2302; 99.4% identity (99.7% similar) in 317 aa overlap (1-317:1-316)
10 20 30 40 50 60
pF1KE4 MVRARHQPGGLCLLLLLLCQFMEDRSAQAGNCWLRQAKNGRCQVLYKTELSKEECCSTGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MVRARHQPGGLCLLLLLLCQFMEDRSAQAGNCWLRQAKNGRCQVLYKTELSKEECCSTGR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 LSTSWTEEDVNDNTLFKWMIFNGGAPNCIPCKETCENVDCGPGKKCRMNKKNKPRCVCAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LSTSWTEEDVNDNTLFKWMIFNGGAPNCIPCKETCENVDCGPGKKCRMNKKNKPRCVCAP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 DCSNITWKGPVCGLDGKTYRNECALLKARCKEQPELEVQYQGRCKKTCRDVFCPGSSTCV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DCSNITWKGPVCGLDGKTYRNECALLKARCKEQPELEVQYQGRCKKTCRDVFCPGSSTCV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 VDQTNNAYCVTCNRICPEPASSEQYLCGNDGVTYSSACHLRKATCLLGRSIGLAYEGKCI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VDQTNNAYCVTCNRICPEPASSEQYLCGNDGVTYSSACHLRKATCLLGRSIGLAYEGKCI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 KAKSCEDIQCTGGKKCLWDFKVGRGRCSLCDELCPDSKSDEPVCASDNATYASECAMKEA
.::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 -TKSCEDIQCTGGKKCLWDFKVGRGRCSLCDELCPDSKSDEPVCASDNATYASECAMKEA
250 260 270 280 290
310 320 330 340
pF1KE4 ACSSGVLLEVKHSGSCNSISEDTEEEEEDEDQDYSFPISSILEW
:::::::::::::::::
XP_005 ACSSGVLLEVKHSGSCN
300 310
>>XP_005248459 (OMIM: 136470) PREDICTED: follistatin iso (330 aa)
initn: 1903 init1: 1768 opt: 1788 Z-score: 1480.2 bits: 282.3 E(85289): 1e-75
Smith-Waterman score: 2284; 95.8% identity (96.1% similar) in 330 aa overlap (1-317:1-330)
10 20 30 40 50 60
pF1KE4 MVRARHQPGGLCLLLLLLCQFMEDRSAQAGNCWLRQAKNGRCQVLYKTELSKEECCSTGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MVRARHQPGGLCLLLLLLCQFMEDRSAQAGNCWLRQAKNGRCQVLYKTELSKEECCSTGR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 LSTSWTEEDVNDNTLFKWMIFNGGAPNCIPCKETCENVDCGPGKKCRMNKKNKPRCVCAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LSTSWTEEDVNDNTLFKWMIFNGGAPNCIPCKETCENVDCGPGKKCRMNKKNKPRCVCAP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 DCSNITWKGPVCGLDGKTYRNECALLKARCKEQPELEVQYQGRCKKTCRDVFCPGSSTCV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DCSNITWKGPVCGLDGKTYRNECALLKARCKEQPELEVQYQGRCKKTCRDVFCPGSSTCV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 VDQTNNAYCVTCNRICPEPASSEQYLCGNDGVTYSSACHLRKATCLLGRSIGLAYEGKCI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VDQTNNAYCVTCNRICPEPASSEQYLCGNDGVTYSSACHLRKATCLLGRSIGLAYEGKCI
190 200 210 220 230 240
250 260 270 280
pF1KE4 -------------KAKSCEDIQCTGGKKCLWDFKVGRGRCSLCDELCPDSKSDEPVCASD
.::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SRYSGLRKEKEKTEAKSCEDIQCTGGKKCLWDFKVGRGRCSLCDELCPDSKSDEPVCASD
250 260 270 280 290 300
290 300 310 320 330 340
pF1KE4 NATYASECAMKEAACSSGVLLEVKHSGSCNSISEDTEEEEEDEDQDYSFPISSILEW
::::::::::::::::::::::::::::::
XP_005 NATYASECAMKEAACSSGVLLEVKHSGSCN
310 320 330
>>XP_016864443 (OMIM: 136470) PREDICTED: follistatin iso (337 aa)
initn: 1768 init1: 1768 opt: 1788 Z-score: 1480.1 bits: 282.3 E(85289): 1.1e-75
Smith-Waterman score: 2289; 95.8% identity (96.1% similar) in 331 aa overlap (1-318:1-331)
10 20 30 40 50 60
pF1KE4 MVRARHQPGGLCLLLLLLCQFMEDRSAQAGNCWLRQAKNGRCQVLYKTELSKEECCSTGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MVRARHQPGGLCLLLLLLCQFMEDRSAQAGNCWLRQAKNGRCQVLYKTELSKEECCSTGR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 LSTSWTEEDVNDNTLFKWMIFNGGAPNCIPCKETCENVDCGPGKKCRMNKKNKPRCVCAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSTSWTEEDVNDNTLFKWMIFNGGAPNCIPCKETCENVDCGPGKKCRMNKKNKPRCVCAP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 DCSNITWKGPVCGLDGKTYRNECALLKARCKEQPELEVQYQGRCKKTCRDVFCPGSSTCV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DCSNITWKGPVCGLDGKTYRNECALLKARCKEQPELEVQYQGRCKKTCRDVFCPGSSTCV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 VDQTNNAYCVTCNRICPEPASSEQYLCGNDGVTYSSACHLRKATCLLGRSIGLAYEGKCI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VDQTNNAYCVTCNRICPEPASSEQYLCGNDGVTYSSACHLRKATCLLGRSIGLAYEGKCI
190 200 210 220 230 240
250 260 270 280
pF1KE4 -------------KAKSCEDIQCTGGKKCLWDFKVGRGRCSLCDELCPDSKSDEPVCASD
.::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SRYSGLRKEKEKTEAKSCEDIQCTGGKKCLWDFKVGRGRCSLCDELCPDSKSDEPVCASD
250 260 270 280 290 300
290 300 310 320 330 340
pF1KE4 NATYASECAMKEAACSSGVLLEVKHSGSCNSISEDTEEEEEDEDQDYSFPISSILEW
:::::::::::::::::::::::::::::::
XP_016 NATYASECAMKEAACSSGVLLEVKHSGSCNSPLYSPI
310 320 330
>>XP_005248457 (OMIM: 136470) PREDICTED: follistatin iso (357 aa)
initn: 1903 init1: 1768 opt: 1788 Z-score: 1479.8 bits: 282.3 E(85289): 1.1e-75
Smith-Waterman score: 2462; 96.1% identity (96.4% similar) in 357 aa overlap (1-344:1-357)
10 20 30 40 50 60
pF1KE4 MVRARHQPGGLCLLLLLLCQFMEDRSAQAGNCWLRQAKNGRCQVLYKTELSKEECCSTGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MVRARHQPGGLCLLLLLLCQFMEDRSAQAGNCWLRQAKNGRCQVLYKTELSKEECCSTGR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 LSTSWTEEDVNDNTLFKWMIFNGGAPNCIPCKETCENVDCGPGKKCRMNKKNKPRCVCAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LSTSWTEEDVNDNTLFKWMIFNGGAPNCIPCKETCENVDCGPGKKCRMNKKNKPRCVCAP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 DCSNITWKGPVCGLDGKTYRNECALLKARCKEQPELEVQYQGRCKKTCRDVFCPGSSTCV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DCSNITWKGPVCGLDGKTYRNECALLKARCKEQPELEVQYQGRCKKTCRDVFCPGSSTCV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 VDQTNNAYCVTCNRICPEPASSEQYLCGNDGVTYSSACHLRKATCLLGRSIGLAYEGKCI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VDQTNNAYCVTCNRICPEPASSEQYLCGNDGVTYSSACHLRKATCLLGRSIGLAYEGKCI
190 200 210 220 230 240
250 260 270 280
pF1KE4 -------------KAKSCEDIQCTGGKKCLWDFKVGRGRCSLCDELCPDSKSDEPVCASD
.::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SRYSGLRKEKEKTEAKSCEDIQCTGGKKCLWDFKVGRGRCSLCDELCPDSKSDEPVCASD
250 260 270 280 290 300
290 300 310 320 330 340
pF1KE4 NATYASECAMKEAACSSGVLLEVKHSGSCNSISEDTEEEEEDEDQDYSFPISSILEW
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NATYASECAMKEAACSSGVLLEVKHSGSCNSISEDTEEEEEDEDQDYSFPISSILEW
310 320 330 340 350
>>XP_011541401 (OMIM: 136470) PREDICTED: follistatin iso (352 aa)
initn: 1708 init1: 1573 opt: 1593 Z-score: 1320.4 bits: 252.8 E(85289): 8.3e-67
Smith-Waterman score: 2267; 95.7% identity (96.0% similar) in 329 aa overlap (29-344:24-352)
10 20 30 40 50 60
pF1KE4 MVRARHQPGGLCLLLLLLCQFMEDRSAQAGNCWLRQAKNGRCQVLYKTELSKEECCSTGR
::::::::::::::::::::::::::::::::
XP_011 MGRIKVNSLVKVNASCTCCVWVTAGNCWLRQAKNGRCQVLYKTELSKEECCSTGR
10 20 30 40 50
70 80 90 100 110 120
pF1KE4 LSTSWTEEDVNDNTLFKWMIFNGGAPNCIPCKETCENVDCGPGKKCRMNKKNKPRCVCAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSTSWTEEDVNDNTLFKWMIFNGGAPNCIPCKETCENVDCGPGKKCRMNKKNKPRCVCAP
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE4 DCSNITWKGPVCGLDGKTYRNECALLKARCKEQPELEVQYQGRCKKTCRDVFCPGSSTCV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DCSNITWKGPVCGLDGKTYRNECALLKARCKEQPELEVQYQGRCKKTCRDVFCPGSSTCV
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE4 VDQTNNAYCVTCNRICPEPASSEQYLCGNDGVTYSSACHLRKATCLLGRSIGLAYEGKCI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VDQTNNAYCVTCNRICPEPASSEQYLCGNDGVTYSSACHLRKATCLLGRSIGLAYEGKCI
180 190 200 210 220 230
250 260 270 280
pF1KE4 -------------KAKSCEDIQCTGGKKCLWDFKVGRGRCSLCDELCPDSKSDEPVCASD
.::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SRYSGLRKEKEKTEAKSCEDIQCTGGKKCLWDFKVGRGRCSLCDELCPDSKSDEPVCASD
240 250 260 270 280 290
290 300 310 320 330 340
pF1KE4 NATYASECAMKEAACSSGVLLEVKHSGSCNSISEDTEEEEEDEDQDYSFPISSILEW
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NATYASECAMKEAACSSGVLLEVKHSGSCNSISEDTEEEEEDEDQDYSFPISSILEW
300 310 320 330 340 350
>>XP_016864444 (OMIM: 136470) PREDICTED: follistatin iso (279 aa)
initn: 1348 init1: 1213 opt: 1233 Z-score: 1027.2 bits: 198.2 E(85289): 1.8e-50
Smith-Waterman score: 1907; 95.0% identity (95.3% similar) in 279 aa overlap (79-344:1-279)
50 60 70 80 90 100
pF1KE4 ELSKEECCSTGRLSTSWTEEDVNDNTLFKWMIFNGGAPNCIPCKETCENVDCGPGKKCRM
::::::::::::::::::::::::::::::
XP_016 MIFNGGAPNCIPCKETCENVDCGPGKKCRM
10 20 30
110 120 130 140 150 160
pF1KE4 NKKNKPRCVCAPDCSNITWKGPVCGLDGKTYRNECALLKARCKEQPELEVQYQGRCKKTC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NKKNKPRCVCAPDCSNITWKGPVCGLDGKTYRNECALLKARCKEQPELEVQYQGRCKKTC
40 50 60 70 80 90
170 180 190 200 210 220
pF1KE4 RDVFCPGSSTCVVDQTNNAYCVTCNRICPEPASSEQYLCGNDGVTYSSACHLRKATCLLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RDVFCPGSSTCVVDQTNNAYCVTCNRICPEPASSEQYLCGNDGVTYSSACHLRKATCLLG
100 110 120 130 140 150
230 240 250 260 270
pF1KE4 RSIGLAYEGKCI-------------KAKSCEDIQCTGGKKCLWDFKVGRGRCSLCDELCP
:::::::::::: .::::::::::::::::::::::::::::::::::
XP_016 RSIGLAYEGKCISRYSGLRKEKEKTEAKSCEDIQCTGGKKCLWDFKVGRGRCSLCDELCP
160 170 180 190 200 210
280 290 300 310 320 330
pF1KE4 DSKSDEPVCASDNATYASECAMKEAACSSGVLLEVKHSGSCNSISEDTEEEEEDEDQDYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DSKSDEPVCASDNATYASECAMKEAACSSGVLLEVKHSGSCNSISEDTEEEEEDEDQDYS
220 230 240 250 260 270
340
pF1KE4 FPISSILEW
:::::::::
XP_016 FPISSILEW
>>NP_005851 (OMIM: 605343) follistatin-related protein 3 (263 aa)
initn: 693 init1: 373 opt: 817 Z-score: 687.2 bits: 135.2 E(85289): 1.5e-31
Smith-Waterman score: 817; 48.1% identity (77.1% similar) in 214 aa overlap (27-239:33-243)
10 20 30 40 50
pF1KE4 MVRARHQPGGLCLLLLLLCQFMEDRSAQAGNCWLRQAKNGRCQVLYKTELSKEECC
: .: :::.:.... :... .:.... :::
NP_005 PGAPGPLWPLPWGALAWAVGFVSSMGSGNPAPGGVCWLQQGQEATCSLVLQTDVTRAECC
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE4 STGRLSTSWTEEDVNDNTLFKWMIFNGGAPNCIPCKETCENVDCGPGKKCRMNKKNKPRC
..: ..:.:.. : . . . : : . .:.:::..:..:.::::: ::: ..:::
NP_005 ASGNIDTAWSNLTHPGNKI-NLLGFLGLV-HCLPCKDSCDGVECGPGKACRM-LGGRPRC
70 80 90 100 110
120 130 140 150 160 170
pF1KE4 VCAPDCSNITWKGPVCGLDGKTYRNECALLKARCKEQPELEVQYQGRCKKTCRDVFCPGS
::::::.. . ::: :: :::.:: : :::. .:.: :.:.:::.:.:. : ::
NP_005 ECAPDCSGLPARLQVCGSDGATYRDECELRAARCRGHPDLSVMYRGRCRKSCEHVVCPRP
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE4 STCVVDQTNNAYCVTCNRI-CPEPASSEQYLCGNDGVTYSSACHLRKATCLLGRSIGLAY
..::::::..:.::.: :: :.: : ::::..::: :.::.:.:::.::::::. .
NP_005 QSCVVDQTGSAHCVVCRAAPCPVPSSPGQELCGNNNVTYISSCHMRQATCFLGRSIGVRH
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE4 EGKCIKAKSCEDIQCTGGKKCLWDFKVGRGRCSLCDELCPDSKSDEPVCASDNATYASEC
:.:
NP_005 AGSCAGTPEEPPGGESAEEEENFV
240 250 260
344 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 02:14:26 2016 done: Sun Nov 6 02:14:27 2016
Total Scan time: 8.190 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]