FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE4317, 323 aa
  1>>>pF1KE4317 323 - 323 aa - 323 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.1715+/-0.000321; mu= 17.0135+/- 0.020
 mean_var=76.6285+/-14.494, 0's: 0 Z-trim(117.3): 51  B-trim: 47 in 1/53
 Lambda= 0.146514
 statistics sampled from 29068 (29119) to 29068 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.718), E-opt: 0.2 (0.341), width:  16
 Scan time:  7.830

The best scores are:                                      opt bits E(85289)
NP_002344 (OMIM: 137290,204870) tumor-associated c ( 323) 2176 469.1 5.5e-132
NP_002345 (OMIM: 185535,613217,613244) epithelial  ( 314) 1013 223.3 5.4e-58
XP_011542497 (OMIM: 131390) PREDICTED: nidogen-1 i (1205)  159 43.2  0.0033
NP_002499 (OMIM: 131390) nidogen-1 precursor [Homo (1247)  159 43.2  0.0033


>>NP_002344 (OMIM: 137290,204870) tumor-associated calci  (323 aa)
 initn: 2176 init1: 2176 opt: 2176  Z-score: 2490.6  bits: 469.1 E(85289): 5.5e-132
Smith-Waterman score: 2176; 100.0% identity (100.0% similar) in 323 aa overlap (1-323:1-323)

               10        20        30        40        50        60
pF1KE4 MARGPGLAPPPLRLPLLLLVLAAVTGHTAAQDNCTCPTNKMTVCSPDGPGGRCQCRALGS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MARGPGLAPPPLRLPLLLLVLAAVTGHTAAQDNCTCPTNKMTVCSPDGPGGRCQCRALGS
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE4 GMAVDCSTLTSKCLLLKARMSAPKNARTLVRPSEHALVDNDGLYDPDCDPEGRFKARQCN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 GMAVDCSTLTSKCLLLKARMSAPKNARTLVRPSEHALVDNDGLYDPDCDPEGRFKARQCN
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE4 QTSVCWCVNSVGVRRTDKGDLSLRCDELVRTHHILIDLRHRPTAGAFNHSDLDAELRRLF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 QTSVCWCVNSVGVRRTDKGDLSLRCDELVRTHHILIDLRHRPTAGAFNHSDLDAELRRLF
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE4 RERYRLHPKFVAAVHYEQPTIQIELRQNTSQKAAGDVDIGDAAYYFERDIKGESLFQGRG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 RERYRLHPKFVAAVHYEQPTIQIELRQNTSQKAAGDVDIGDAAYYFERDIKGESLFQGRG
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE4 GLDLRVRGEPLQVERTLIYYLDEIPPKFSMKRLTAGLIAVIVVVVVALVAGMAVLVITNR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 GLDLRVRGEPLQVERTLIYYLDEIPPKFSMKRLTAGLIAVIVVVVVALVAGMAVLVITNR
              250       260       270       280       290       300

              310       320   
pF1KE4 RKSGKYKKVEIKELGELRKEPSL
       :::::::::::::::::::::::
NP_002 RKSGKYKKVEIKELGELRKEPSL
              310       320   

>>NP_002345 (OMIM: 185535,613217,613244) epithelial cell  (314 aa)
 initn: 923 init1: 416 opt: 1013  Z-score: 1162.2  bits: 223.3 E(85289): 5.4e-58
Smith-Waterman score: 1013; 49.7% identity (78.8% similar) in 316 aa overlap (7-320:1-311)

               10        20        30        40        50        60
pF1KE4 MARGPGLAPPPLRLPLLLLVLAAVTGHTAAQDNCTCPTNKMTVCSPDGPGGRCQCRALGS
             .::: . : . ::. ::..  .:::..:.: . :..:    . . .::: ..:.
NP_002       MAPPQV-LAFGLLLAAATATFAAAQEECVCENYKLAVNCFVNNNRQCQCTSVGA
                      10        20        30        40        50   

               70        80        90       100       110       120
pF1KE4 GMAVDCSTLTSKCLLLKARMSAPKNARTLVRPSEHALVDNDGLYDPDCDPEGRFKARQCN
         .: :: :..:::..::.:.. : .:  ..: : :: .::::::::::  : :::.:::
NP_002 QNTVICSKLAAKCLVMKAEMNGSKLGRR-AKP-EGALQNNDGLYDPDCDESGLFKAKQCN
            60        70        80          90       100       110 

              130       140       150       160       170       180
pF1KE4 QTSVCWCVNSVGVRRTDKGDLSLRCDELVRTHHILIDLRHRPTAGAFNHSDLDAELRRLF
        ::.:::::..::::::: :  . :.: :::. :.:.:.:.     .. ..: . :.. .
NP_002 GTSMCWCVNTAGVRRTDK-DTEITCSERVRTYWIIIELKHKAREKPYDSKSLRTALQKEI
             120        130       140       150       160       170

              190       200       210       220       230       240
pF1KE4 RERYRLHPKFVAAVHYEQPTIQIELRQNTSQKAAGDVDIGDAAYYFERDIKGESLFQGRG
         ::.: :::.... ::. .: :.: ::.:::. .::::.:.:::::.:.::::::... 
NP_002 TTRYQLDPKFITSILYENNVITIDLVQNSSQKTQNDVDIADVAYYFEKDVKGESLFHSKK
              180       190       200       210       220       230

              250         260       270       280       290        
pF1KE4 GLDLRVRGEPLQVE--RTLIYYLDEIPPKFSMKRLTAGLIAVIVVVVVALVAGMAVLVIT
        .:: : :: :...  .:::::.::  :.:::. : ::.::::::::.:.:::..::::.
NP_002 -MDLTVNGEQLDLDPGQTLIYYVDEKAPEFSMQGLKAGVIAVIVVVVIAVVAGIVVLVIS
               240       250       260       270       280         

      300       310       320   
pF1KE4 NRRKSGKYKKVEIKELGELRKEPSL
        ... .::.:.::::.::...:   
NP_002 RKKRMAKYEKAEIKEMGEMHRELNA
     290       300       310    

>>XP_011542497 (OMIM: 131390) PREDICTED: nidogen-1 isofo  (1205 aa)
 initn: 103 init1:  77 opt: 159  Z-score: 178.7  bits: 43.2 E(85289): 0.0033
Smith-Waterman score: 159; 28.1% identity (49.1% similar) in 114 aa overlap (29-132:757-861)

                 10        20        30        40             50   
pF1KE4   MARGPGLAPPPLRLPLLLLVLAAVTGHTAAQDNCTCPTNKMTVCSPDG-----PGG-R
                                     : ::   :  ..   : ::.     ::.  
XP_011 CDIPQRAQCIYTGGSSYTCSCLPGFSGDGQACQDVDECQPSR---CHPDAFCYNTPGSFT
        730       740       750       760          770       780   

             60           70        80        90       100         
pF1KE4 CQCRALGSGMAVDC---STLTSKCLLLKARMSAPKNARTLVRPSEHALVDNDGLYDPDCD
       :::.   .: .  :    .  ..:   . .. .  .:    ::         ::. :.::
XP_011 CQCKPGYQGDGFRCVPGEVEKTRCQHEREHILGAAGATDPQRPIP------PGLFVPECD
           790       800       810       820             830       

     110       120        130       140       150       160        
pF1KE4 PEGRFKARQCN-QTSVCWCVNSVGVRRTDKGDLSLRCDELVRTHHILIDLRHRPTAGAFN
        .:..   ::. .:. ::::.  :                                    
XP_011 AHGHYAPTQCHGSTGYCWCVDRDGREVEGTRTRPGMTPPCLSTVAPPIHQGPAVPTAVIP
       840       850       860       870       880       890       

>>NP_002499 (OMIM: 131390) nidogen-1 precursor [Homo sap  (1247 aa)
 initn: 103 init1:  77 opt: 159  Z-score: 178.5  bits: 43.2 E(85289): 0.0033
Smith-Waterman score: 159; 28.1% identity (49.1% similar) in 114 aa overlap (29-132:799-903)

                 10        20        30        40             50   
pF1KE4   MARGPGLAPPPLRLPLLLLVLAAVTGHTAAQDNCTCPTNKMTVCSPDG-----PGG-R
                                     : ::   :  ..   : ::.     ::.  
NP_002 CDIPQRAQCIYTGGSSYTCSCLPGFSGDGQACQDVDECQPSR---CHPDAFCYNTPGSFT
      770       780       790       800       810          820     

             60           70        80        90       100         
pF1KE4 CQCRALGSGMAVDC---STLTSKCLLLKARMSAPKNARTLVRPSEHALVDNDGLYDPDCD
       :::.   .: .  :    .  ..:   . .. .  .:    ::         ::. :.::
NP_002 CQCKPGYQGDGFRCVPGEVEKTRCQHEREHILGAAGATDPQRPIP------PGLFVPECD
         830       840       850       860       870               

     110       120        130       140       150       160        
pF1KE4 PEGRFKARQCN-QTSVCWCVNSVGVRRTDKGDLSLRCDELVRTHHILIDLRHRPTAGAFN
        .:..   ::. .:. ::::.  :                                    
NP_002 AHGHYAPTQCHGSTGYCWCVDRDGREVEGTRTRPGMTPPCLSTVAPPIHQGPAVPTAVIP
     880       890       900       910       920       930         




323 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 23:13:01 2016 done: Sat Nov  5 23:13:02 2016
 Total Scan time:  7.830 Total Display time:  0.010

Function used was FASTA [36.3.4 Apr, 2011]