FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE4304, 301 aa
  1>>>pF1KE4304 301 - 301 aa - 301 aa
Library: human.CCDS.faa
  18511270 residues in 32554 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.6815+/-0.000808; mu= 13.6122+/- 0.048
 mean_var=84.2546+/-17.257, 0's: 0 Z-trim(108.3): 63  B-trim: 0 in 0/51
 Lambda= 0.139726
 statistics sampled from 10074 (10134) to 10074 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.69), E-opt: 0.2 (0.311), width:  16
 Scan time:  2.410

The best scores are:                                      opt bits E(32554)
CCDS4333.1 HAVCR2 gene_id:84868|Hs108|chr5         ( 301) 2020 416.9 9.3e-117
CCDS43392.1 HAVCR1 gene_id:26762|Hs108|chr5        ( 364)  344 79.1 5.5e-15
CCDS78076.1 HAVCR1 gene_id:26762|Hs108|chr5        ( 401)  344 79.1 5.9e-15
CCDS54943.1 TIMD4 gene_id:91937|Hs108|chr5         ( 350)  333 76.9 2.5e-14
CCDS4332.1 TIMD4 gene_id:91937|Hs108|chr5          ( 378)  333 76.9 2.6e-14


>>CCDS4333.1 HAVCR2 gene_id:84868|Hs108|chr5              (301 aa)
 initn: 2020 init1: 2020 opt: 2020  Z-score: 2209.6  bits: 416.9 E(32554): 9.3e-117
Smith-Waterman score: 2020; 99.7% identity (99.7% similar) in 301 aa overlap (1-301:1-301)

               10        20        30        40        50        60
pF1KE4 MFSHLPFDCVLLLLLLLLTRSSEVEYRAEVGQNAYLPCFYTPAAPGNLVPVCWGKGACPV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 MFSHLPFDCVLLLLLLLLTRSSEVEYRAEVGQNAYLPCFYTPAAPGNLVPVCWGKGACPV
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE4 FECGNVVLRTDERDVNYWTSRYWLNGDFRKGDVSLTIENVTLADSGIYCCRIQIPGIMND
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 FECGNVVLRTDERDVNYWTSRYWLNGDFRKGDVSLTIENVTLADSGIYCCRIQIPGIMND
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE4 EKFNLKLVIKPAKVTPAPTLQRDFTAAFPRMLTTRGHGPAETQTLGSLPDINLTQISTLA
       ::::::::::::::::::: ::::::::::::::::::::::::::::::::::::::::
CCDS43 EKFNLKLVIKPAKVTPAPTRQRDFTAAFPRMLTTRGHGPAETQTLGSLPDINLTQISTLA
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE4 NELRDSRLANDLRDSGATIRIGIYIGAGICAGLALALIFGALIFKWYSHSKEKIQNLSLI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 NELRDSRLANDLRDSGATIRIGIYIGAGICAGLALALIFGALIFKWYSHSKEKIQNLSLI
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE4 SLANLPPSGLANAVAEGIRSEENIYTIEENVYEVEEPNEYYCYVSSRQQPSQPLGCRFAM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 SLANLPPSGLANAVAEGIRSEENIYTIEENVYEVEEPNEYYCYVSSRQQPSQPLGCRFAM
              250       260       270       280       290       300

        
pF1KE4 P
       :
CCDS43 P
        

>>CCDS43392.1 HAVCR1 gene_id:26762|Hs108|chr5             (364 aa)
 initn: 364 init1: 210 opt: 344  Z-score: 382.5  bits: 79.1 E(32554): 5.5e-15
Smith-Waterman score: 344; 36.0% identity (62.8% similar) in 172 aa overlap (10-178:6-168)

               10        20          30        40        50        
pF1KE4 MFSHLPFDCVLLLLLLLLTRS--SEVEYRAEVGQNAYLPCFYTPAAPGNLVPVCWGKGAC
                :.: :.: :. :  . :.  .:.: .. ::: :.    : .. .::..:.:
CCDS43     MHPQVVILSLILHLADSVAGSVKVGGEAGPSVTLPCHYS----GAVTSMCWNRGSC
                   10        20        30            40        50  

       60        70         80        90       100       110       
pF1KE4 PVFECGNVVLRTDERDVNYWT-SRYWLNGDFRKGDVSLTIENVTLADSGIYCCRIQIPGI
        .: : : .. :.   :.:   .:: : ::. . ::::::::....:::.::::..  : 
CCDS43 SLFTCQNGIVWTNGTHVTYRKDTRYKLLGDLSRRDVSLTIENTAVSDSGVYCCRVEHRGW
             60        70        80        90       100       110  

       120       130       140       150       160       170       
pF1KE4 MNDEKFNLKLVIKPAKVTPAPTLQRDFTAAFPRMLTTRGHGPAETQTLGSLPDINLTQIS
       .:: :....: : : ::: .: .     .. : . :.:    . : :   .  .  : . 
CCDS43 FNDMKITVSLEIVPPKVTTTPIV-----TTVPTVTTVRTSTTVPTTTTVPMTTVPTTTVP
            120       130            140       150       160       

       180       190       200       210       220       230       
pF1KE4 TLANELRDSRLANDLRDSGATIRIGIYIGAGICAGLALALIFGALIFKWYSHSKEKIQNL
       :                                                           
CCDS43 TTMSIPTTTTVLTTMTVSTTTSVPTTTSIPTTTSVPVTTTVSTFVPPMPLPRQNHEPVAT
       170       180       190       200       210       220       

>>CCDS78076.1 HAVCR1 gene_id:26762|Hs108|chr5             (401 aa)
 initn: 340 init1: 210 opt: 344  Z-score: 381.9  bits: 79.1 E(32554): 5.9e-15
Smith-Waterman score: 344; 36.0% identity (62.8% similar) in 172 aa overlap (10-178:6-168)

               10        20          30        40        50        
pF1KE4 MFSHLPFDCVLLLLLLLLTRS--SEVEYRAEVGQNAYLPCFYTPAAPGNLVPVCWGKGAC
                :.: :.: :. :  . :.  .:.: .. ::: :.    : .. .::..:.:
CCDS78     MHPQVVILSLILHLADSVAGSVKVGGEAGPSVTLPCHYS----GAVTSMCWNRGSC
                   10        20        30            40        50  

       60        70         80        90       100       110       
pF1KE4 PVFECGNVVLRTDERDVNYWT-SRYWLNGDFRKGDVSLTIENVTLADSGIYCCRIQIPGI
        .: : : .. :.   :.:   .:: : ::. . ::::::::....:::.::::..  : 
CCDS78 SLFTCQNGIVWTNGTHVTYRKDTRYKLLGDLSRRDVSLTIENTAVSDSGVYCCRVEHRGW
             60        70        80        90       100       110  

       120       130       140       150       160       170       
pF1KE4 MNDEKFNLKLVIKPAKVTPAPTLQRDFTAAFPRMLTTRGHGPAETQTLGSLPDINLTQIS
       .:: :....: : : ::: .: .     .. : . :.:    . : :   .  .  : . 
CCDS78 FNDMKITVSLEIVPPKVTTTPIV-----TTVPTVTTVRTSTTVPTTTTVPMTTVPTTTVP
            120       130            140       150       160       

       180       190       200       210       220       230       
pF1KE4 TLANELRDSRLANDLRDSGATIRIGIYIGAGICAGLALALIFGALIFKWYSHSKEKIQNL
       :                                                           
CCDS78 TTMSIPTTTTVLTTMTVSTTTSVPTTTSIPTTTSVPVTTTVSTFVPPMPLPRQNHEPVAT
       170       180       190       200       210       220       

>>CCDS54943.1 TIMD4 gene_id:91937|Hs108|chr5              (350 aa)
 initn: 276 init1: 199 opt: 333  Z-score: 370.8  bits: 76.9 E(32554): 2.5e-14
Smith-Waterman score: 333; 35.6% identity (60.3% similar) in 174 aa overlap (15-180:17-189)

                 10        20        30        40        50        
pF1KE4   MFSHLPFDCVLLLLLLLLTRSSEVEYRAEVGQNAYLPCFYTPAAPGNLVPVCWGKGAC
                       : :   .::.     .:. . :::.:.  .  :   .::::  :
CCDS54 MSKEPLILWLMIEFWWLYLTPVTSETVVTEVLGHRVTLPCLYSSWSH-NSNSMCWGKDQC
               10        20        30        40         50         

       60        70         80        90       100       110       
pF1KE4 PVFECGNVVLRTD-ERDVNYWTSRYWLNGDFRKGDVSLTIENVTLADSGIYCCRIQIPGI
       :   : ....:::  : ..  ...: :.: . .::::::: : . .:::.:::::..:: 
CCDS54 PYSGCKEALIRTDGMRVTSRKSAKYRLQGTIPRGDVSLTILNPSESDSGVYCCRIEVPGW
      60        70        80        90       100       110         

       120       130          140       150       160        170   
pF1KE4 MNDEKFNLKLVIKPAKVTP---APTLQRDFTAAFPRMLTTRGHGPAETQT-LGSLPDINL
       .:: :.:..: .. :..:    : :  :  :.. :         ::   : . . ::.. 
CCDS54 FNDVKINVRLNLQRASTTTHRTATTTTRRTTTTSPTTTRQMTTTPAALPTTVVTTPDLTT
     120       130       140       150       160       170         

              180       190       200       210       220       230
pF1KE4 ---TQISTLANELRDSRLANDLRDSGATIRIGIYIGAGICAGLALALIFGALIFKWYSHS
           :..:.:                                                  
CCDS54 GTPLQMTTIAVFTTANTCLSLTPSTLPEEATGLLTPEPSKEGPILTAESETVLPSDSWSS
     180       190       200       210       220       230         

>>CCDS4332.1 TIMD4 gene_id:91937|Hs108|chr5               (378 aa)
 initn: 276 init1: 199 opt: 333  Z-score: 370.3  bits: 76.9 E(32554): 2.6e-14
Smith-Waterman score: 333; 35.6% identity (60.3% similar) in 174 aa overlap (15-180:17-189)

                 10        20        30        40        50        
pF1KE4   MFSHLPFDCVLLLLLLLLTRSSEVEYRAEVGQNAYLPCFYTPAAPGNLVPVCWGKGAC
                       : :   .::.     .:. . :::.:.  .  :   .::::  :
CCDS43 MSKEPLILWLMIEFWWLYLTPVTSETVVTEVLGHRVTLPCLYSSWSH-NSNSMCWGKDQC
               10        20        30        40         50         

       60        70         80        90       100       110       
pF1KE4 PVFECGNVVLRTD-ERDVNYWTSRYWLNGDFRKGDVSLTIENVTLADSGIYCCRIQIPGI
       :   : ....:::  : ..  ...: :.: . .::::::: : . .:::.:::::..:: 
CCDS43 PYSGCKEALIRTDGMRVTSRKSAKYRLQGTIPRGDVSLTILNPSESDSGVYCCRIEVPGW
      60        70        80        90       100       110         

       120       130          140       150       160        170   
pF1KE4 MNDEKFNLKLVIKPAKVTP---APTLQRDFTAAFPRMLTTRGHGPAETQT-LGSLPDINL
       .:: :.:..: .. :..:    : :  :  :.. :         ::   : . . ::.. 
CCDS43 FNDVKINVRLNLQRASTTTHRTATTTTRRTTTTSPTTTRQMTTTPAALPTTVVTTPDLTT
     120       130       140       150       160       170         

              180       190       200       210       220       230
pF1KE4 ---TQISTLANELRDSRLANDLRDSGATIRIGIYIGAGICAGLALALIFGALIFKWYSHS
           :..:.:                                                  
CCDS43 GTPLQMTTIAVFTTANTCLSLTPSTLPEEATGLLTPEPSKEGPILTAESETVLPSDSWSS
     180       190       200       210       220       230         




301 residues in 1 query   sequences
18511270 residues in 32554 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 23:29:09 2016 done: Sat Nov  5 23:29:10 2016
 Total Scan time:  2.410 Total Display time:  0.010

Function used was FASTA [36.3.4 Apr, 2011]