Result of FASTA (omim) for
pFN21AE4261
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE4261, 1057 aa
1>>>pF1KE4261 1057 - 1057 aa - 1057 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.7535+/-0.000455; mu= 19.1018+/- 0.028
mean_var=73.4775+/-15.337, 0's: 0 Z-trim(108.4): 352 B-trim: 0 in 0/49
Lambda= 0.149623
statistics sampled from 16174 (16533) to 16174 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.54), E-opt: 0.2 (0.194), width: 16
Scan time: 11.700
The best scores are: opt bits E(85289)
NP_071362 (OMIM: 609248) probable E3 ubiquitin-pro (1057) 7135 1550.7 0
NP_056416 (OMIM: 609248) probable E3 ubiquitin-pro (1049) 7055 1533.4 0
XP_011537898 (OMIM: 609248) PREDICTED: probable E3 ( 987) 6601 1435.4 0
XP_011537896 (OMIM: 609248) PREDICTED: probable E3 (1011) 6248 1359.2 0
XP_011537897 (OMIM: 609248) PREDICTED: probable E3 (1011) 6248 1359.2 0
XP_011537894 (OMIM: 609248) PREDICTED: probable E3 (1081) 6248 1359.2 0
XP_011537895 (OMIM: 609248) PREDICTED: probable E3 (1073) 6168 1341.9 0
NP_001265114 (OMIM: 609248) probable E3 ubiquitin- ( 979) 5336 1162.3 0
NP_001265115 (OMIM: 609248) probable E3 ubiquitin- ( 794) 5283 1150.8 0
NP_055421 (OMIM: 605200) probable E3 ubiquitin-pro (1050) 3972 867.9 0
XP_005263384 (OMIM: 605200) PREDICTED: probable E3 (1050) 3972 867.9 0
NP_001258531 (OMIM: 605200) probable E3 ubiquitin- ( 932) 3512 768.6 0
XP_016871530 (OMIM: 609248) PREDICTED: probable E3 ( 936) 3341 731.7 4.7e-210
XP_005263388 (OMIM: 605200) PREDICTED: probable E3 ( 903) 3179 696.7 1.5e-199
XP_005263389 (OMIM: 605200) PREDICTED: probable E3 ( 896) 3176 696.1 2.4e-199
XP_011537899 (OMIM: 609248) PREDICTED: probable E3 ( 960) 3028 664.1 1e-189
XP_005263387 (OMIM: 605200) PREDICTED: probable E3 ( 993) 2345 516.7 2.6e-145
XP_016864297 (OMIM: 605200) PREDICTED: probable E3 ( 580) 2270 500.4 1.2e-140
XP_005263386 (OMIM: 605200) PREDICTED: probable E3 (1042) 2209 487.4 1.8e-136
XP_016864295 (OMIM: 605200) PREDICTED: probable E3 (1042) 2209 487.4 1.8e-136
XP_011530699 (OMIM: 605200) PREDICTED: probable E3 ( 494) 1984 438.6 4e-122
XP_016864296 (OMIM: 605200) PREDICTED: probable E3 ( 924) 1791 397.1 2.4e-109
NP_001305434 (OMIM: 605200) probable E3 ubiquitin- ( 368) 1449 323.1 1.8e-87
XP_016863822 (OMIM: 609249) PREDICTED: probable E3 ( 614) 1111 250.2 2.6e-65
XP_006720739 (OMIM: 105830,601623) PREDICTED: ubiq ( 852) 1022 231.1 2.1e-59
XP_005268325 (OMIM: 105830,601623) PREDICTED: ubiq ( 852) 1022 231.1 2.1e-59
XP_005268324 (OMIM: 105830,601623) PREDICTED: ubiq ( 852) 1022 231.1 2.1e-59
XP_005268326 (OMIM: 105830,601623) PREDICTED: ubiq ( 852) 1022 231.1 2.1e-59
XP_016878041 (OMIM: 105830,601623) PREDICTED: ubiq ( 852) 1022 231.1 2.1e-59
NP_570853 (OMIM: 105830,601623) ubiquitin-protein ( 852) 1022 231.1 2.1e-59
XP_006720738 (OMIM: 105830,601623) PREDICTED: ubiq ( 852) 1022 231.1 2.1e-59
XP_016878042 (OMIM: 105830,601623) PREDICTED: ubiq ( 852) 1022 231.1 2.1e-59
XP_005268327 (OMIM: 105830,601623) PREDICTED: ubiq ( 852) 1022 231.1 2.1e-59
XP_016878040 (OMIM: 105830,601623) PREDICTED: ubiq ( 852) 1022 231.1 2.1e-59
XP_005268328 (OMIM: 105830,601623) PREDICTED: ubiq ( 852) 1022 231.1 2.1e-59
XP_016878043 (OMIM: 105830,601623) PREDICTED: ubiq ( 852) 1022 231.1 2.1e-59
XP_016878044 (OMIM: 105830,601623) PREDICTED: ubiq ( 852) 1022 231.1 2.1e-59
XP_016878038 (OMIM: 105830,601623) PREDICTED: ubiq ( 872) 1022 231.1 2.1e-59
XP_016878036 (OMIM: 105830,601623) PREDICTED: ubiq ( 872) 1022 231.1 2.1e-59
XP_016878039 (OMIM: 105830,601623) PREDICTED: ubiq ( 872) 1022 231.1 2.1e-59
NP_570854 (OMIM: 105830,601623) ubiquitin-protein ( 872) 1022 231.1 2.1e-59
XP_016878037 (OMIM: 105830,601623) PREDICTED: ubiq ( 872) 1022 231.1 2.1e-59
NP_000453 (OMIM: 105830,601623) ubiquitin-protein ( 875) 1022 231.1 2.1e-59
XP_011520297 (OMIM: 105830,601623) PREDICTED: ubiq ( 875) 1022 231.1 2.1e-59
XP_016878034 (OMIM: 105830,601623) PREDICTED: ubiq ( 875) 1022 231.1 2.1e-59
XP_011520296 (OMIM: 105830,601623) PREDICTED: ubiq ( 875) 1022 231.1 2.1e-59
XP_016878033 (OMIM: 105830,601623) PREDICTED: ubiq ( 875) 1022 231.1 2.1e-59
XP_016878035 (OMIM: 105830,601623) PREDICTED: ubiq ( 875) 1022 231.1 2.1e-59
NP_001158608 (OMIM: 609249) probable E3 ubiquitin- ( 986) 912 207.4 3.3e-52
NP_060382 (OMIM: 609249) probable E3 ubiquitin-pro (1022) 912 207.4 3.4e-52
>>NP_071362 (OMIM: 609248) probable E3 ubiquitin-protein (1057 aa)
initn: 7135 init1: 7135 opt: 7135 Z-score: 8317.5 bits: 1550.7 E(85289): 0
Smith-Waterman score: 7135; 100.0% identity (100.0% similar) in 1057 aa overlap (1-1057:1-1057)
10 20 30 40 50 60
pF1KE4 MLCWGNASFGQLGLGGIDEEIVLEPRKSDFFINKRVRDVGCGLRHTVFVLDDGTVYTCGC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 MLCWGNASFGQLGLGGIDEEIVLEPRKSDFFINKRVRDVGCGLRHTVFVLDDGTVYTCGC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 NDLGQLGHEKSRKKPEQVVALDAQNIVAVSCGEAHTLALNDKGQVYAWGLDSDGQLGLVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 NDLGQLGHEKSRKKPEQVVALDAQNIVAVSCGEAHTLALNDKGQVYAWGLDSDGQLGLVG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 SEECIRVPRNIKSLSDIQIVQVACGYYHSLALSKASEVFCWGQNKYGQLGLGTDCKKQTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 SEECIRVPRNIKSLSDIQIVQVACGYYHSLALSKASEVFCWGQNKYGQLGLGTDCKKQTS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 PQLLKSLLGIPFMQVAAGGAHSFVLTLSGAIFGWGRNKFGQLGLNDENDRYVPNLLKSLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 PQLLKSLLGIPFMQVAAGGAHSFVLTLSGAIFGWGRNKFGQLGLNDENDRYVPNLLKSLR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 SQKIVYICCGEDHTAALTKEGGVFTFGAGGYGQLGHNSTSHEINPRKVFELMGSIVTEIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 SQKIVYICCGEDHTAALTKEGGVFTFGAGGYGQLGHNSTSHEINPRKVFELMGSIVTEIA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 CGRQHTSAFVPSSGRIYSFGLGGNGQLGTGSTSNRKSPFTVKGNWYPYNGQCLPDIDSEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 CGRQHTSAFVPSSGRIYSFGLGGNGQLGTGSTSNRKSPFTVKGNWYPYNGQCLPDIDSEE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 YFCVKRIFSGGDQSFSHYSSPQNCGPPDDFRCPNPTKQIWTVNEALIQKWLSYPSGRFPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 YFCVKRIFSGGDQSFSHYSSPQNCGPPDDFRCPNPTKQIWTVNEALIQKWLSYPSGRFPV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE4 EIANEIDGTFSSSGCLNGSFLAVSNDDHYRTGTRFSGVDMNAARLLFHKLIQPDHPQISQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 EIANEIDGTFSSSGCLNGSFLAVSNDDHYRTGTRFSGVDMNAARLLFHKLIQPDHPQISQ
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE4 QVAASLEKNLIPKLTSSLPDVEALRFYLTLPECPLMSDSNNFTTIAIPFGTALVNLEKAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 QVAASLEKNLIPKLTSSLPDVEALRFYLTLPECPLMSDSNNFTTIAIPFGTALVNLEKAP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE4 LKVLENWWSVLEPPLFLKIVELFKEVVVHLLKLYKIGIPPSERRIFNSFLHTALKVLEIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 LKVLENWWSVLEPPLFLKIVELFKEVVVHLLKLYKIGIPPSERRIFNSFLHTALKVLEIL
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE4 HRVNEKMGQIIQYDKFYIHEVQELIDIRNDYINWVQQQAYGMDVNHGLTELADIPVTICT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 HRVNEKMGQIIQYDKFYIHEVQELIDIRNDYINWVQQQAYGMDVNHGLTELADIPVTICT
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE4 YPFVFDAQAKTTLLQTDAVLQMQMAIDQAHRQNVSSLFLPVIESVNPCLILVVRRENIVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 YPFVFDAQAKTTLLQTDAVLQMQMAIDQAHRQNVSSLFLPVIESVNPCLILVVRRENIVG
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE4 DAMEVLRKTKNIDYKKPLKVIFVGEDAVDAGGVRKEFFLLIMRELLDPKYGMFRYYEDSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 DAMEVLRKTKNIDYKKPLKVIFVGEDAVDAGGVRKEFFLLIMRELLDPKYGMFRYYEDSR
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE4 LIWFSDKTFEDSDLFHLIGVICGLAIYNCTIVDLHFPLALYKKLLKKKPSLDDLKELMPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 LIWFSDKTFEDSDLFHLIGVICGLAIYNCTIVDLHFPLALYKKLLKKKPSLDDLKELMPD
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE4 VGRSMQQLLDYPEDDIEETFCLNFTITVENFGATEVKELVLNGADTAVNKQNRQEFVDAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 VGRSMQQLLDYPEDDIEETFCLNFTITVENFGATEVKELVLNGADTAVNKQNRQEFVDAY
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE4 VDYIFNKSVASLFDAFHAGFHKVCGGKVLLLFQPNELQAMVIGNTNYDWKELEKNTEYKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 VDYIFNKSVASLFDAFHAGFHKVCGGKVLLLFQPNELQAMVIGNTNYDWKELEKNTEYKG
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE4 EYWAEHPTIKIFWEVFHELPLEKKKQFLLFLTGSDRIPILGMKSLKLVIQSTGGGEEYLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 EYWAEHPTIKIFWEVFHELPLEKKKQFLLFLTGSDRIPILGMKSLKLVIQSTGGGEEYLP
970 980 990 1000 1010 1020
1030 1040 1050
pF1KE4 VSHTCFNLLDLPKYTEKETLRSKLIQAIDHNEGFSLI
:::::::::::::::::::::::::::::::::::::
NP_071 VSHTCFNLLDLPKYTEKETLRSKLIQAIDHNEGFSLI
1030 1040 1050
>>NP_056416 (OMIM: 609248) probable E3 ubiquitin-protein (1049 aa)
initn: 7067 init1: 4387 opt: 7055 Z-score: 8224.2 bits: 1533.4 E(85289): 0
Smith-Waterman score: 7055; 99.2% identity (99.2% similar) in 1057 aa overlap (1-1057:1-1049)
10 20 30 40 50 60
pF1KE4 MLCWGNASFGQLGLGGIDEEIVLEPRKSDFFINKRVRDVGCGLRHTVFVLDDGTVYTCGC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 MLCWGNASFGQLGLGGIDEEIVLEPRKSDFFINKRVRDVGCGLRHTVFVLDDGTVYTCGC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 NDLGQLGHEKSRKKPEQVVALDAQNIVAVSCGEAHTLALNDKGQVYAWGLDSDGQLGLVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 NDLGQLGHEKSRKKPEQVVALDAQNIVAVSCGEAHTLALNDKGQVYAWGLDSDGQLGLVG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 SEECIRVPRNIKSLSDIQIVQVACGYYHSLALSKASEVFCWGQNKYGQLGLGTDCKKQTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 SEECIRVPRNIKSLSDIQIVQVACGYYHSLALSKASEVFCWGQNKYGQLGLGTDCKKQTS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 PQLLKSLLGIPFMQVAAGGAHSFVLTLSGAIFGWGRNKFGQLGLNDENDRYVPNLLKSLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 PQLLKSLLGIPFMQVAAGGAHSFVLTLSGAIFGWGRNKFGQLGLNDENDRYVPNLLKSLR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 SQKIVYICCGEDHTAALTKEGGVFTFGAGGYGQLGHNSTSHEINPRKVFELMGSIVTEIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 SQKIVYICCGEDHTAALTKEGGVFTFGAGGYGQLGHNSTSHEINPRKVFELMGSIVTEIA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 CGRQHTSAFVPSSGRIYSFGLGGNGQLGTGSTSNRKSPFTVKGNWYPYNGQCLPDIDSEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 CGRQHTSAFVPSSGRIYSFGLGGNGQLGTGSTSNRKSPFTVKGNWYPYNGQCLPDIDSEE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 YFCVKRIFSGGDQSFSHYSSPQNCGPPDDFRCPNPTKQIWTVNEALIQKWLSYPSGRFPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 YFCVKRIFSGGDQSFSHYSSPQNCGPPDDFRCPNPTKQIWTVNEALIQKWLSYPSGRFPV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE4 EIANEIDGTFSSSGCLNGSFLAVSNDDHYRTGTRFSGVDMNAARLLFHKLIQPDHPQISQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 EIANEIDGTFSSSGCLNGSFLAVSNDDHYRTGTRFSGVDMNAARLLFHKLIQPDHPQISQ
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE4 QVAASLEKNLIPKLTSSLPDVEALRFYLTLPECPLMSDSNNFTTIAIPFGTALVNLEKAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 QVAASLEKNLIPKLTSSLPDVEALRFYLTLPECPLMSDSNNFTTIAIPFGTALVNLEKAP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE4 LKVLENWWSVLEPPLFLKIVELFKEVVVHLLKLYKIGIPPSERRIFNSFLHTALKVLEIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 LKVLENWWSVLEPPLFLKIVELFKEVVVHLLKLYKIGIPPSERRIFNSFLHTALKVLEIL
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE4 HRVNEKMGQIIQYDKFYIHEVQELIDIRNDYINWVQQQAYGMDVNHGLTELADIPVTICT
:::::::::::::::::::::::::::::::::::::::::: ::::::::::
NP_056 HRVNEKMGQIIQYDKFYIHEVQELIDIRNDYINWVQQQAYGM--------LADIPVTICT
610 620 630 640 650
670 680 690 700 710 720
pF1KE4 YPFVFDAQAKTTLLQTDAVLQMQMAIDQAHRQNVSSLFLPVIESVNPCLILVVRRENIVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 YPFVFDAQAKTTLLQTDAVLQMQMAIDQAHRQNVSSLFLPVIESVNPCLILVVRRENIVG
660 670 680 690 700 710
730 740 750 760 770 780
pF1KE4 DAMEVLRKTKNIDYKKPLKVIFVGEDAVDAGGVRKEFFLLIMRELLDPKYGMFRYYEDSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 DAMEVLRKTKNIDYKKPLKVIFVGEDAVDAGGVRKEFFLLIMRELLDPKYGMFRYYEDSR
720 730 740 750 760 770
790 800 810 820 830 840
pF1KE4 LIWFSDKTFEDSDLFHLIGVICGLAIYNCTIVDLHFPLALYKKLLKKKPSLDDLKELMPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 LIWFSDKTFEDSDLFHLIGVICGLAIYNCTIVDLHFPLALYKKLLKKKPSLDDLKELMPD
780 790 800 810 820 830
850 860 870 880 890 900
pF1KE4 VGRSMQQLLDYPEDDIEETFCLNFTITVENFGATEVKELVLNGADTAVNKQNRQEFVDAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 VGRSMQQLLDYPEDDIEETFCLNFTITVENFGATEVKELVLNGADTAVNKQNRQEFVDAY
840 850 860 870 880 890
910 920 930 940 950 960
pF1KE4 VDYIFNKSVASLFDAFHAGFHKVCGGKVLLLFQPNELQAMVIGNTNYDWKELEKNTEYKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 VDYIFNKSVASLFDAFHAGFHKVCGGKVLLLFQPNELQAMVIGNTNYDWKELEKNTEYKG
900 910 920 930 940 950
970 980 990 1000 1010 1020
pF1KE4 EYWAEHPTIKIFWEVFHELPLEKKKQFLLFLTGSDRIPILGMKSLKLVIQSTGGGEEYLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 EYWAEHPTIKIFWEVFHELPLEKKKQFLLFLTGSDRIPILGMKSLKLVIQSTGGGEEYLP
960 970 980 990 1000 1010
1030 1040 1050
pF1KE4 VSHTCFNLLDLPKYTEKETLRSKLIQAIDHNEGFSLI
:::::::::::::::::::::::::::::::::::::
NP_056 VSHTCFNLLDLPKYTEKETLRSKLIQAIDHNEGFSLI
1020 1030 1040
>>XP_011537898 (OMIM: 609248) PREDICTED: probable E3 ubi (987 aa)
initn: 6601 init1: 6601 opt: 6601 Z-score: 7695.0 bits: 1435.4 E(85289): 0
Smith-Waterman score: 6601; 100.0% identity (100.0% similar) in 982 aa overlap (76-1057:6-987)
50 60 70 80 90 100
pF1KE4 TVFVLDDGTVYTCGCNDLGQLGHEKSRKKPEQVVALDAQNIVAVSCGEAHTLALNDKGQV
::::::::::::::::::::::::::::::
XP_011 MAAHVEQVVALDAQNIVAVSCGEAHTLALNDKGQV
10 20 30
110 120 130 140 150 160
pF1KE4 YAWGLDSDGQLGLVGSEECIRVPRNIKSLSDIQIVQVACGYYHSLALSKASEVFCWGQNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YAWGLDSDGQLGLVGSEECIRVPRNIKSLSDIQIVQVACGYYHSLALSKASEVFCWGQNK
40 50 60 70 80 90
170 180 190 200 210 220
pF1KE4 YGQLGLGTDCKKQTSPQLLKSLLGIPFMQVAAGGAHSFVLTLSGAIFGWGRNKFGQLGLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YGQLGLGTDCKKQTSPQLLKSLLGIPFMQVAAGGAHSFVLTLSGAIFGWGRNKFGQLGLN
100 110 120 130 140 150
230 240 250 260 270 280
pF1KE4 DENDRYVPNLLKSLRSQKIVYICCGEDHTAALTKEGGVFTFGAGGYGQLGHNSTSHEINP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DENDRYVPNLLKSLRSQKIVYICCGEDHTAALTKEGGVFTFGAGGYGQLGHNSTSHEINP
160 170 180 190 200 210
290 300 310 320 330 340
pF1KE4 RKVFELMGSIVTEIACGRQHTSAFVPSSGRIYSFGLGGNGQLGTGSTSNRKSPFTVKGNW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RKVFELMGSIVTEIACGRQHTSAFVPSSGRIYSFGLGGNGQLGTGSTSNRKSPFTVKGNW
220 230 240 250 260 270
350 360 370 380 390 400
pF1KE4 YPYNGQCLPDIDSEEYFCVKRIFSGGDQSFSHYSSPQNCGPPDDFRCPNPTKQIWTVNEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YPYNGQCLPDIDSEEYFCVKRIFSGGDQSFSHYSSPQNCGPPDDFRCPNPTKQIWTVNEA
280 290 300 310 320 330
410 420 430 440 450 460
pF1KE4 LIQKWLSYPSGRFPVEIANEIDGTFSSSGCLNGSFLAVSNDDHYRTGTRFSGVDMNAARL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LIQKWLSYPSGRFPVEIANEIDGTFSSSGCLNGSFLAVSNDDHYRTGTRFSGVDMNAARL
340 350 360 370 380 390
470 480 490 500 510 520
pF1KE4 LFHKLIQPDHPQISQQVAASLEKNLIPKLTSSLPDVEALRFYLTLPECPLMSDSNNFTTI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LFHKLIQPDHPQISQQVAASLEKNLIPKLTSSLPDVEALRFYLTLPECPLMSDSNNFTTI
400 410 420 430 440 450
530 540 550 560 570 580
pF1KE4 AIPFGTALVNLEKAPLKVLENWWSVLEPPLFLKIVELFKEVVVHLLKLYKIGIPPSERRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AIPFGTALVNLEKAPLKVLENWWSVLEPPLFLKIVELFKEVVVHLLKLYKIGIPPSERRI
460 470 480 490 500 510
590 600 610 620 630 640
pF1KE4 FNSFLHTALKVLEILHRVNEKMGQIIQYDKFYIHEVQELIDIRNDYINWVQQQAYGMDVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FNSFLHTALKVLEILHRVNEKMGQIIQYDKFYIHEVQELIDIRNDYINWVQQQAYGMDVN
520 530 540 550 560 570
650 660 670 680 690 700
pF1KE4 HGLTELADIPVTICTYPFVFDAQAKTTLLQTDAVLQMQMAIDQAHRQNVSSLFLPVIESV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HGLTELADIPVTICTYPFVFDAQAKTTLLQTDAVLQMQMAIDQAHRQNVSSLFLPVIESV
580 590 600 610 620 630
710 720 730 740 750 760
pF1KE4 NPCLILVVRRENIVGDAMEVLRKTKNIDYKKPLKVIFVGEDAVDAGGVRKEFFLLIMREL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NPCLILVVRRENIVGDAMEVLRKTKNIDYKKPLKVIFVGEDAVDAGGVRKEFFLLIMREL
640 650 660 670 680 690
770 780 790 800 810 820
pF1KE4 LDPKYGMFRYYEDSRLIWFSDKTFEDSDLFHLIGVICGLAIYNCTIVDLHFPLALYKKLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LDPKYGMFRYYEDSRLIWFSDKTFEDSDLFHLIGVICGLAIYNCTIVDLHFPLALYKKLL
700 710 720 730 740 750
830 840 850 860 870 880
pF1KE4 KKKPSLDDLKELMPDVGRSMQQLLDYPEDDIEETFCLNFTITVENFGATEVKELVLNGAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KKKPSLDDLKELMPDVGRSMQQLLDYPEDDIEETFCLNFTITVENFGATEVKELVLNGAD
760 770 780 790 800 810
890 900 910 920 930 940
pF1KE4 TAVNKQNRQEFVDAYVDYIFNKSVASLFDAFHAGFHKVCGGKVLLLFQPNELQAMVIGNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TAVNKQNRQEFVDAYVDYIFNKSVASLFDAFHAGFHKVCGGKVLLLFQPNELQAMVIGNT
820 830 840 850 860 870
950 960 970 980 990 1000
pF1KE4 NYDWKELEKNTEYKGEYWAEHPTIKIFWEVFHELPLEKKKQFLLFLTGSDRIPILGMKSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NYDWKELEKNTEYKGEYWAEHPTIKIFWEVFHELPLEKKKQFLLFLTGSDRIPILGMKSL
880 890 900 910 920 930
1010 1020 1030 1040 1050
pF1KE4 KLVIQSTGGGEEYLPVSHTCFNLLDLPKYTEKETLRSKLIQAIDHNEGFSLI
::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KLVIQSTGGGEEYLPVSHTCFNLLDLPKYTEKETLRSKLIQAIDHNEGFSLI
940 950 960 970 980
>>XP_011537896 (OMIM: 609248) PREDICTED: probable E3 ubi (1011 aa)
initn: 6587 init1: 6248 opt: 6248 Z-score: 7283.0 bits: 1359.2 E(85289): 0
Smith-Waterman score: 6543; 97.6% identity (97.6% similar) in 1006 aa overlap (76-1057:6-1011)
50 60 70 80 90 100
pF1KE4 TVFVLDDGTVYTCGCNDLGQLGHEKSRKKPEQVVALDAQNIVAVSCGEAHTLALNDKGQV
::::::::::::::::::::::::::::::
XP_011 MAAHVEQVVALDAQNIVAVSCGEAHTLALNDKGQV
10 20 30
110 120 130 140
pF1KE4 YAWGLDSDGQLGLVGSEECIRVP------------------------RNIKSLSDIQIVQ
::::::::::::::::::::::: :::::::::::::
XP_011 YAWGLDSDGQLGLVGSEECIRVPSCFPKIMCVDSLVRICSGLSYGRIRNIKSLSDIQIVQ
40 50 60 70 80 90
150 160 170 180 190 200
pF1KE4 VACGYYHSLALSKASEVFCWGQNKYGQLGLGTDCKKQTSPQLLKSLLGIPFMQVAAGGAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VACGYYHSLALSKASEVFCWGQNKYGQLGLGTDCKKQTSPQLLKSLLGIPFMQVAAGGAH
100 110 120 130 140 150
210 220 230 240 250 260
pF1KE4 SFVLTLSGAIFGWGRNKFGQLGLNDENDRYVPNLLKSLRSQKIVYICCGEDHTAALTKEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SFVLTLSGAIFGWGRNKFGQLGLNDENDRYVPNLLKSLRSQKIVYICCGEDHTAALTKEG
160 170 180 190 200 210
270 280 290 300 310 320
pF1KE4 GVFTFGAGGYGQLGHNSTSHEINPRKVFELMGSIVTEIACGRQHTSAFVPSSGRIYSFGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GVFTFGAGGYGQLGHNSTSHEINPRKVFELMGSIVTEIACGRQHTSAFVPSSGRIYSFGL
220 230 240 250 260 270
330 340 350 360 370 380
pF1KE4 GGNGQLGTGSTSNRKSPFTVKGNWYPYNGQCLPDIDSEEYFCVKRIFSGGDQSFSHYSSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GGNGQLGTGSTSNRKSPFTVKGNWYPYNGQCLPDIDSEEYFCVKRIFSGGDQSFSHYSSP
280 290 300 310 320 330
390 400 410 420 430 440
pF1KE4 QNCGPPDDFRCPNPTKQIWTVNEALIQKWLSYPSGRFPVEIANEIDGTFSSSGCLNGSFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QNCGPPDDFRCPNPTKQIWTVNEALIQKWLSYPSGRFPVEIANEIDGTFSSSGCLNGSFL
340 350 360 370 380 390
450 460 470 480 490 500
pF1KE4 AVSNDDHYRTGTRFSGVDMNAARLLFHKLIQPDHPQISQQVAASLEKNLIPKLTSSLPDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AVSNDDHYRTGTRFSGVDMNAARLLFHKLIQPDHPQISQQVAASLEKNLIPKLTSSLPDV
400 410 420 430 440 450
510 520 530 540 550 560
pF1KE4 EALRFYLTLPECPLMSDSNNFTTIAIPFGTALVNLEKAPLKVLENWWSVLEPPLFLKIVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EALRFYLTLPECPLMSDSNNFTTIAIPFGTALVNLEKAPLKVLENWWSVLEPPLFLKIVE
460 470 480 490 500 510
570 580 590 600 610 620
pF1KE4 LFKEVVVHLLKLYKIGIPPSERRIFNSFLHTALKVLEILHRVNEKMGQIIQYDKFYIHEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LFKEVVVHLLKLYKIGIPPSERRIFNSFLHTALKVLEILHRVNEKMGQIIQYDKFYIHEV
520 530 540 550 560 570
630 640 650 660 670 680
pF1KE4 QELIDIRNDYINWVQQQAYGMDVNHGLTELADIPVTICTYPFVFDAQAKTTLLQTDAVLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QELIDIRNDYINWVQQQAYGMDVNHGLTELADIPVTICTYPFVFDAQAKTTLLQTDAVLQ
580 590 600 610 620 630
690 700 710 720 730 740
pF1KE4 MQMAIDQAHRQNVSSLFLPVIESVNPCLILVVRRENIVGDAMEVLRKTKNIDYKKPLKVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MQMAIDQAHRQNVSSLFLPVIESVNPCLILVVRRENIVGDAMEVLRKTKNIDYKKPLKVI
640 650 660 670 680 690
750 760 770 780 790 800
pF1KE4 FVGEDAVDAGGVRKEFFLLIMRELLDPKYGMFRYYEDSRLIWFSDKTFEDSDLFHLIGVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FVGEDAVDAGGVRKEFFLLIMRELLDPKYGMFRYYEDSRLIWFSDKTFEDSDLFHLIGVI
700 710 720 730 740 750
810 820 830 840 850 860
pF1KE4 CGLAIYNCTIVDLHFPLALYKKLLKKKPSLDDLKELMPDVGRSMQQLLDYPEDDIEETFC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CGLAIYNCTIVDLHFPLALYKKLLKKKPSLDDLKELMPDVGRSMQQLLDYPEDDIEETFC
760 770 780 790 800 810
870 880 890 900 910 920
pF1KE4 LNFTITVENFGATEVKELVLNGADTAVNKQNRQEFVDAYVDYIFNKSVASLFDAFHAGFH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LNFTITVENFGATEVKELVLNGADTAVNKQNRQEFVDAYVDYIFNKSVASLFDAFHAGFH
820 830 840 850 860 870
930 940 950 960 970 980
pF1KE4 KVCGGKVLLLFQPNELQAMVIGNTNYDWKELEKNTEYKGEYWAEHPTIKIFWEVFHELPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KVCGGKVLLLFQPNELQAMVIGNTNYDWKELEKNTEYKGEYWAEHPTIKIFWEVFHELPL
880 890 900 910 920 930
990 1000 1010 1020 1030 1040
pF1KE4 EKKKQFLLFLTGSDRIPILGMKSLKLVIQSTGGGEEYLPVSHTCFNLLDLPKYTEKETLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKKKQFLLFLTGSDRIPILGMKSLKLVIQSTGGGEEYLPVSHTCFNLLDLPKYTEKETLR
940 950 960 970 980 990
1050
pF1KE4 SKLIQAIDHNEGFSLI
::::::::::::::::
XP_011 SKLIQAIDHNEGFSLI
1000 1010
>>XP_011537897 (OMIM: 609248) PREDICTED: probable E3 ubi (1011 aa)
initn: 6587 init1: 6248 opt: 6248 Z-score: 7283.0 bits: 1359.2 E(85289): 0
Smith-Waterman score: 6543; 97.6% identity (97.6% similar) in 1006 aa overlap (76-1057:6-1011)
50 60 70 80 90 100
pF1KE4 TVFVLDDGTVYTCGCNDLGQLGHEKSRKKPEQVVALDAQNIVAVSCGEAHTLALNDKGQV
::::::::::::::::::::::::::::::
XP_011 MAAHVEQVVALDAQNIVAVSCGEAHTLALNDKGQV
10 20 30
110 120 130 140
pF1KE4 YAWGLDSDGQLGLVGSEECIRVP------------------------RNIKSLSDIQIVQ
::::::::::::::::::::::: :::::::::::::
XP_011 YAWGLDSDGQLGLVGSEECIRVPSCFPKIMCVDSLVRICSGLSYGRIRNIKSLSDIQIVQ
40 50 60 70 80 90
150 160 170 180 190 200
pF1KE4 VACGYYHSLALSKASEVFCWGQNKYGQLGLGTDCKKQTSPQLLKSLLGIPFMQVAAGGAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VACGYYHSLALSKASEVFCWGQNKYGQLGLGTDCKKQTSPQLLKSLLGIPFMQVAAGGAH
100 110 120 130 140 150
210 220 230 240 250 260
pF1KE4 SFVLTLSGAIFGWGRNKFGQLGLNDENDRYVPNLLKSLRSQKIVYICCGEDHTAALTKEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SFVLTLSGAIFGWGRNKFGQLGLNDENDRYVPNLLKSLRSQKIVYICCGEDHTAALTKEG
160 170 180 190 200 210
270 280 290 300 310 320
pF1KE4 GVFTFGAGGYGQLGHNSTSHEINPRKVFELMGSIVTEIACGRQHTSAFVPSSGRIYSFGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GVFTFGAGGYGQLGHNSTSHEINPRKVFELMGSIVTEIACGRQHTSAFVPSSGRIYSFGL
220 230 240 250 260 270
330 340 350 360 370 380
pF1KE4 GGNGQLGTGSTSNRKSPFTVKGNWYPYNGQCLPDIDSEEYFCVKRIFSGGDQSFSHYSSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GGNGQLGTGSTSNRKSPFTVKGNWYPYNGQCLPDIDSEEYFCVKRIFSGGDQSFSHYSSP
280 290 300 310 320 330
390 400 410 420 430 440
pF1KE4 QNCGPPDDFRCPNPTKQIWTVNEALIQKWLSYPSGRFPVEIANEIDGTFSSSGCLNGSFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QNCGPPDDFRCPNPTKQIWTVNEALIQKWLSYPSGRFPVEIANEIDGTFSSSGCLNGSFL
340 350 360 370 380 390
450 460 470 480 490 500
pF1KE4 AVSNDDHYRTGTRFSGVDMNAARLLFHKLIQPDHPQISQQVAASLEKNLIPKLTSSLPDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AVSNDDHYRTGTRFSGVDMNAARLLFHKLIQPDHPQISQQVAASLEKNLIPKLTSSLPDV
400 410 420 430 440 450
510 520 530 540 550 560
pF1KE4 EALRFYLTLPECPLMSDSNNFTTIAIPFGTALVNLEKAPLKVLENWWSVLEPPLFLKIVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EALRFYLTLPECPLMSDSNNFTTIAIPFGTALVNLEKAPLKVLENWWSVLEPPLFLKIVE
460 470 480 490 500 510
570 580 590 600 610 620
pF1KE4 LFKEVVVHLLKLYKIGIPPSERRIFNSFLHTALKVLEILHRVNEKMGQIIQYDKFYIHEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LFKEVVVHLLKLYKIGIPPSERRIFNSFLHTALKVLEILHRVNEKMGQIIQYDKFYIHEV
520 530 540 550 560 570
630 640 650 660 670 680
pF1KE4 QELIDIRNDYINWVQQQAYGMDVNHGLTELADIPVTICTYPFVFDAQAKTTLLQTDAVLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QELIDIRNDYINWVQQQAYGMDVNHGLTELADIPVTICTYPFVFDAQAKTTLLQTDAVLQ
580 590 600 610 620 630
690 700 710 720 730 740
pF1KE4 MQMAIDQAHRQNVSSLFLPVIESVNPCLILVVRRENIVGDAMEVLRKTKNIDYKKPLKVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MQMAIDQAHRQNVSSLFLPVIESVNPCLILVVRRENIVGDAMEVLRKTKNIDYKKPLKVI
640 650 660 670 680 690
750 760 770 780 790 800
pF1KE4 FVGEDAVDAGGVRKEFFLLIMRELLDPKYGMFRYYEDSRLIWFSDKTFEDSDLFHLIGVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FVGEDAVDAGGVRKEFFLLIMRELLDPKYGMFRYYEDSRLIWFSDKTFEDSDLFHLIGVI
700 710 720 730 740 750
810 820 830 840 850 860
pF1KE4 CGLAIYNCTIVDLHFPLALYKKLLKKKPSLDDLKELMPDVGRSMQQLLDYPEDDIEETFC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CGLAIYNCTIVDLHFPLALYKKLLKKKPSLDDLKELMPDVGRSMQQLLDYPEDDIEETFC
760 770 780 790 800 810
870 880 890 900 910 920
pF1KE4 LNFTITVENFGATEVKELVLNGADTAVNKQNRQEFVDAYVDYIFNKSVASLFDAFHAGFH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LNFTITVENFGATEVKELVLNGADTAVNKQNRQEFVDAYVDYIFNKSVASLFDAFHAGFH
820 830 840 850 860 870
930 940 950 960 970 980
pF1KE4 KVCGGKVLLLFQPNELQAMVIGNTNYDWKELEKNTEYKGEYWAEHPTIKIFWEVFHELPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KVCGGKVLLLFQPNELQAMVIGNTNYDWKELEKNTEYKGEYWAEHPTIKIFWEVFHELPL
880 890 900 910 920 930
990 1000 1010 1020 1030 1040
pF1KE4 EKKKQFLLFLTGSDRIPILGMKSLKLVIQSTGGGEEYLPVSHTCFNLLDLPKYTEKETLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKKKQFLLFLTGSDRIPILGMKSLKLVIQSTGGGEEYLPVSHTCFNLLDLPKYTEKETLR
940 950 960 970 980 990
1050
pF1KE4 SKLIQAIDHNEGFSLI
::::::::::::::::
XP_011 SKLIQAIDHNEGFSLI
1000 1010
>>XP_011537894 (OMIM: 609248) PREDICTED: probable E3 ubi (1081 aa)
initn: 7121 init1: 6248 opt: 6248 Z-score: 7282.6 bits: 1359.2 E(85289): 0
Smith-Waterman score: 7077; 97.8% identity (97.8% similar) in 1081 aa overlap (1-1057:1-1081)
10 20 30 40 50 60
pF1KE4 MLCWGNASFGQLGLGGIDEEIVLEPRKSDFFINKRVRDVGCGLRHTVFVLDDGTVYTCGC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MLCWGNASFGQLGLGGIDEEIVLEPRKSDFFINKRVRDVGCGLRHTVFVLDDGTVYTCGC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 NDLGQLGHEKSRKKPEQVVALDAQNIVAVSCGEAHTLALNDKGQVYAWGLDSDGQLGLVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NDLGQLGHEKSRKKPEQVVALDAQNIVAVSCGEAHTLALNDKGQVYAWGLDSDGQLGLVG
70 80 90 100 110 120
130 140 150
pF1KE4 SEECIRVP------------------------RNIKSLSDIQIVQVACGYYHSLALSKAS
:::::::: ::::::::::::::::::::::::::::
XP_011 SEECIRVPSCFPKIMCVDSLVRICSGLSYGRIRNIKSLSDIQIVQVACGYYHSLALSKAS
130 140 150 160 170 180
160 170 180 190 200 210
pF1KE4 EVFCWGQNKYGQLGLGTDCKKQTSPQLLKSLLGIPFMQVAAGGAHSFVLTLSGAIFGWGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EVFCWGQNKYGQLGLGTDCKKQTSPQLLKSLLGIPFMQVAAGGAHSFVLTLSGAIFGWGR
190 200 210 220 230 240
220 230 240 250 260 270
pF1KE4 NKFGQLGLNDENDRYVPNLLKSLRSQKIVYICCGEDHTAALTKEGGVFTFGAGGYGQLGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NKFGQLGLNDENDRYVPNLLKSLRSQKIVYICCGEDHTAALTKEGGVFTFGAGGYGQLGH
250 260 270 280 290 300
280 290 300 310 320 330
pF1KE4 NSTSHEINPRKVFELMGSIVTEIACGRQHTSAFVPSSGRIYSFGLGGNGQLGTGSTSNRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NSTSHEINPRKVFELMGSIVTEIACGRQHTSAFVPSSGRIYSFGLGGNGQLGTGSTSNRK
310 320 330 340 350 360
340 350 360 370 380 390
pF1KE4 SPFTVKGNWYPYNGQCLPDIDSEEYFCVKRIFSGGDQSFSHYSSPQNCGPPDDFRCPNPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPFTVKGNWYPYNGQCLPDIDSEEYFCVKRIFSGGDQSFSHYSSPQNCGPPDDFRCPNPT
370 380 390 400 410 420
400 410 420 430 440 450
pF1KE4 KQIWTVNEALIQKWLSYPSGRFPVEIANEIDGTFSSSGCLNGSFLAVSNDDHYRTGTRFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KQIWTVNEALIQKWLSYPSGRFPVEIANEIDGTFSSSGCLNGSFLAVSNDDHYRTGTRFS
430 440 450 460 470 480
460 470 480 490 500 510
pF1KE4 GVDMNAARLLFHKLIQPDHPQISQQVAASLEKNLIPKLTSSLPDVEALRFYLTLPECPLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GVDMNAARLLFHKLIQPDHPQISQQVAASLEKNLIPKLTSSLPDVEALRFYLTLPECPLM
490 500 510 520 530 540
520 530 540 550 560 570
pF1KE4 SDSNNFTTIAIPFGTALVNLEKAPLKVLENWWSVLEPPLFLKIVELFKEVVVHLLKLYKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SDSNNFTTIAIPFGTALVNLEKAPLKVLENWWSVLEPPLFLKIVELFKEVVVHLLKLYKI
550 560 570 580 590 600
580 590 600 610 620 630
pF1KE4 GIPPSERRIFNSFLHTALKVLEILHRVNEKMGQIIQYDKFYIHEVQELIDIRNDYINWVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GIPPSERRIFNSFLHTALKVLEILHRVNEKMGQIIQYDKFYIHEVQELIDIRNDYINWVQ
610 620 630 640 650 660
640 650 660 670 680 690
pF1KE4 QQAYGMDVNHGLTELADIPVTICTYPFVFDAQAKTTLLQTDAVLQMQMAIDQAHRQNVSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QQAYGMDVNHGLTELADIPVTICTYPFVFDAQAKTTLLQTDAVLQMQMAIDQAHRQNVSS
670 680 690 700 710 720
700 710 720 730 740 750
pF1KE4 LFLPVIESVNPCLILVVRRENIVGDAMEVLRKTKNIDYKKPLKVIFVGEDAVDAGGVRKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LFLPVIESVNPCLILVVRRENIVGDAMEVLRKTKNIDYKKPLKVIFVGEDAVDAGGVRKE
730 740 750 760 770 780
760 770 780 790 800 810
pF1KE4 FFLLIMRELLDPKYGMFRYYEDSRLIWFSDKTFEDSDLFHLIGVICGLAIYNCTIVDLHF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FFLLIMRELLDPKYGMFRYYEDSRLIWFSDKTFEDSDLFHLIGVICGLAIYNCTIVDLHF
790 800 810 820 830 840
820 830 840 850 860 870
pF1KE4 PLALYKKLLKKKPSLDDLKELMPDVGRSMQQLLDYPEDDIEETFCLNFTITVENFGATEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PLALYKKLLKKKPSLDDLKELMPDVGRSMQQLLDYPEDDIEETFCLNFTITVENFGATEV
850 860 870 880 890 900
880 890 900 910 920 930
pF1KE4 KELVLNGADTAVNKQNRQEFVDAYVDYIFNKSVASLFDAFHAGFHKVCGGKVLLLFQPNE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KELVLNGADTAVNKQNRQEFVDAYVDYIFNKSVASLFDAFHAGFHKVCGGKVLLLFQPNE
910 920 930 940 950 960
940 950 960 970 980 990
pF1KE4 LQAMVIGNTNYDWKELEKNTEYKGEYWAEHPTIKIFWEVFHELPLEKKKQFLLFLTGSDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LQAMVIGNTNYDWKELEKNTEYKGEYWAEHPTIKIFWEVFHELPLEKKKQFLLFLTGSDR
970 980 990 1000 1010 1020
1000 1010 1020 1030 1040 1050
pF1KE4 IPILGMKSLKLVIQSTGGGEEYLPVSHTCFNLLDLPKYTEKETLRSKLIQAIDHNEGFSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IPILGMKSLKLVIQSTGGGEEYLPVSHTCFNLLDLPKYTEKETLRSKLIQAIDHNEGFSL
1030 1040 1050 1060 1070 1080
pF1KE4 I
:
XP_011 I
>>XP_011537895 (OMIM: 609248) PREDICTED: probable E3 ubi (1073 aa)
initn: 7053 init1: 3500 opt: 6168 Z-score: 7189.3 bits: 1341.9 E(85289): 0
Smith-Waterman score: 6997; 97.0% identity (97.0% similar) in 1081 aa overlap (1-1057:1-1073)
10 20 30 40 50 60
pF1KE4 MLCWGNASFGQLGLGGIDEEIVLEPRKSDFFINKRVRDVGCGLRHTVFVLDDGTVYTCGC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MLCWGNASFGQLGLGGIDEEIVLEPRKSDFFINKRVRDVGCGLRHTVFVLDDGTVYTCGC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 NDLGQLGHEKSRKKPEQVVALDAQNIVAVSCGEAHTLALNDKGQVYAWGLDSDGQLGLVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NDLGQLGHEKSRKKPEQVVALDAQNIVAVSCGEAHTLALNDKGQVYAWGLDSDGQLGLVG
70 80 90 100 110 120
130 140 150
pF1KE4 SEECIRVP------------------------RNIKSLSDIQIVQVACGYYHSLALSKAS
:::::::: ::::::::::::::::::::::::::::
XP_011 SEECIRVPSCFPKIMCVDSLVRICSGLSYGRIRNIKSLSDIQIVQVACGYYHSLALSKAS
130 140 150 160 170 180
160 170 180 190 200 210
pF1KE4 EVFCWGQNKYGQLGLGTDCKKQTSPQLLKSLLGIPFMQVAAGGAHSFVLTLSGAIFGWGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EVFCWGQNKYGQLGLGTDCKKQTSPQLLKSLLGIPFMQVAAGGAHSFVLTLSGAIFGWGR
190 200 210 220 230 240
220 230 240 250 260 270
pF1KE4 NKFGQLGLNDENDRYVPNLLKSLRSQKIVYICCGEDHTAALTKEGGVFTFGAGGYGQLGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NKFGQLGLNDENDRYVPNLLKSLRSQKIVYICCGEDHTAALTKEGGVFTFGAGGYGQLGH
250 260 270 280 290 300
280 290 300 310 320 330
pF1KE4 NSTSHEINPRKVFELMGSIVTEIACGRQHTSAFVPSSGRIYSFGLGGNGQLGTGSTSNRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NSTSHEINPRKVFELMGSIVTEIACGRQHTSAFVPSSGRIYSFGLGGNGQLGTGSTSNRK
310 320 330 340 350 360
340 350 360 370 380 390
pF1KE4 SPFTVKGNWYPYNGQCLPDIDSEEYFCVKRIFSGGDQSFSHYSSPQNCGPPDDFRCPNPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPFTVKGNWYPYNGQCLPDIDSEEYFCVKRIFSGGDQSFSHYSSPQNCGPPDDFRCPNPT
370 380 390 400 410 420
400 410 420 430 440 450
pF1KE4 KQIWTVNEALIQKWLSYPSGRFPVEIANEIDGTFSSSGCLNGSFLAVSNDDHYRTGTRFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KQIWTVNEALIQKWLSYPSGRFPVEIANEIDGTFSSSGCLNGSFLAVSNDDHYRTGTRFS
430 440 450 460 470 480
460 470 480 490 500 510
pF1KE4 GVDMNAARLLFHKLIQPDHPQISQQVAASLEKNLIPKLTSSLPDVEALRFYLTLPECPLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GVDMNAARLLFHKLIQPDHPQISQQVAASLEKNLIPKLTSSLPDVEALRFYLTLPECPLM
490 500 510 520 530 540
520 530 540 550 560 570
pF1KE4 SDSNNFTTIAIPFGTALVNLEKAPLKVLENWWSVLEPPLFLKIVELFKEVVVHLLKLYKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SDSNNFTTIAIPFGTALVNLEKAPLKVLENWWSVLEPPLFLKIVELFKEVVVHLLKLYKI
550 560 570 580 590 600
580 590 600 610 620 630
pF1KE4 GIPPSERRIFNSFLHTALKVLEILHRVNEKMGQIIQYDKFYIHEVQELIDIRNDYINWVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GIPPSERRIFNSFLHTALKVLEILHRVNEKMGQIIQYDKFYIHEVQELIDIRNDYINWVQ
610 620 630 640 650 660
640 650 660 670 680 690
pF1KE4 QQAYGMDVNHGLTELADIPVTICTYPFVFDAQAKTTLLQTDAVLQMQMAIDQAHRQNVSS
:::::: ::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QQAYGM--------LADIPVTICTYPFVFDAQAKTTLLQTDAVLQMQMAIDQAHRQNVSS
670 680 690 700 710
700 710 720 730 740 750
pF1KE4 LFLPVIESVNPCLILVVRRENIVGDAMEVLRKTKNIDYKKPLKVIFVGEDAVDAGGVRKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LFLPVIESVNPCLILVVRRENIVGDAMEVLRKTKNIDYKKPLKVIFVGEDAVDAGGVRKE
720 730 740 750 760 770
760 770 780 790 800 810
pF1KE4 FFLLIMRELLDPKYGMFRYYEDSRLIWFSDKTFEDSDLFHLIGVICGLAIYNCTIVDLHF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FFLLIMRELLDPKYGMFRYYEDSRLIWFSDKTFEDSDLFHLIGVICGLAIYNCTIVDLHF
780 790 800 810 820 830
820 830 840 850 860 870
pF1KE4 PLALYKKLLKKKPSLDDLKELMPDVGRSMQQLLDYPEDDIEETFCLNFTITVENFGATEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PLALYKKLLKKKPSLDDLKELMPDVGRSMQQLLDYPEDDIEETFCLNFTITVENFGATEV
840 850 860 870 880 890
880 890 900 910 920 930
pF1KE4 KELVLNGADTAVNKQNRQEFVDAYVDYIFNKSVASLFDAFHAGFHKVCGGKVLLLFQPNE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KELVLNGADTAVNKQNRQEFVDAYVDYIFNKSVASLFDAFHAGFHKVCGGKVLLLFQPNE
900 910 920 930 940 950
940 950 960 970 980 990
pF1KE4 LQAMVIGNTNYDWKELEKNTEYKGEYWAEHPTIKIFWEVFHELPLEKKKQFLLFLTGSDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LQAMVIGNTNYDWKELEKNTEYKGEYWAEHPTIKIFWEVFHELPLEKKKQFLLFLTGSDR
960 970 980 990 1000 1010
1000 1010 1020 1030 1040 1050
pF1KE4 IPILGMKSLKLVIQSTGGGEEYLPVSHTCFNLLDLPKYTEKETLRSKLIQAIDHNEGFSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IPILGMKSLKLVIQSTGGGEEYLPVSHTCFNLLDLPKYTEKETLRSKLIQAIDHNEGFSL
1020 1030 1040 1050 1060 1070
pF1KE4 I
:
XP_011 I
>>NP_001265114 (OMIM: 609248) probable E3 ubiquitin-prot (979 aa)
initn: 6592 init1: 5336 opt: 5336 Z-score: 6219.3 bits: 1162.3 E(85289): 0
Smith-Waterman score: 6440; 92.6% identity (92.6% similar) in 1057 aa overlap (1-1057:1-979)
10 20 30 40 50 60
pF1KE4 MLCWGNASFGQLGLGGIDEEIVLEPRKSDFFINKRVRDVGCGLRHTVFVLDDGTVYTCGC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MLCWGNASFGQLGLGGIDEEIVLEPRKSDFFINKRVRDVGCGLRHTVFVLDDGTVYTCGC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 NDLGQLGHEKSRKKPEQVVALDAQNIVAVSCGEAHTLALNDKGQVYAWGLDSDGQLGLVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NDLGQLGHEKSRKKPEQVVALDAQNIVAVSCGEAHTLALNDKGQVYAWGLDSDGQLGLVG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 SEECIRVPRNIKSLSDIQIVQVACGYYHSLALSKASEVFCWGQNKYGQLGLGTDCKKQTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SEECIRVPRNIKSLSDIQIVQVACGYYHSLALSKASEVFCWGQNKYGQLGLGTDCKKQTS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 PQLLKSLLGIPFMQVAAGGAHSFVLTLSGAIFGWGRNKFGQLGLNDENDRYVPNLLKSLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PQLLKSLLGIPFMQVAAGGAHSFVLTLSGAIFGWGRNKFGQLGLNDENDRYVPNLLKSLR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 SQKIVYICCGEDHTAALTKEGGVFTFGAGGYGQLGHNSTSHEINPRKVFELMGSIVTEIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SQKIVYICCGEDHTAALTKEGGVFTFGAGGYGQLGHNSTSHEINPRKVFELMGSIVTEIA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 CGRQHTSAFVPSSGRIYSFGLGGNGQLGTGSTSNRKSPFTVKGNWYPYNGQCLPDIDSEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CGRQHTSAFVPSSGRIYSFGLGGNGQLGTGSTSNRKSPFTVKGNWYPYNGQCLPDIDSEE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 YFCVKRIFSGGDQSFSHYSSPQNCGPPDDFRCPNPTKQIWTVNEALIQKWLSYPSGRFPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YFCVKRIFSGGDQSFSHYSSPQNCGPPDDFRCPNPTKQIWTVNEALIQKWLSYPSGRFPV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE4 EIANEIDGTFSSSGCLNGSFLAVSNDDHYRTGTRFSGVDMNAARLLFHKLIQPDHPQISQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EIANEIDGTFSSSGCLNGSFLAVSNDDHYRTGTRFSGVDMNAARLLFHKLIQPDHPQISQ
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE4 QVAASLEKNLIPKLTSSLPDVEALRFYLTLPECPLMSDSNNFTTIAIPFGTALVNLEKAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QVAASLEKNLIPKLTSSLPDVEALRFYLTLPECPLMSDSNNFTTIAIPFGTALVNLEKAP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE4 LKVLENWWSVLEPPLFLKIVELFKEVVVHLLKLYKIGIPPSERRIFNSFLHTALKVLEIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LKVLENWWSVLEPPLFLKIVELFKEVVVHLLKLYKIGIPPSERRIFNSFLHTALKVLEIL
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE4 HRVNEKMGQIIQYDKFYIHEVQELIDIRNDYINWVQQQAYGMDVNHGLTELADIPVTICT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HRVNEKMGQIIQYDKFYIHEVQELIDIRNDYINWVQQQAYGMDVNHGLTELADIPVTICT
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE4 YPFVFDAQAKTTLLQTDAVLQMQMAIDQAHRQNVSSLFLPVIESVNPCLILVVRRENIVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YPFVFDAQAKTTLLQTDAVLQMQMAIDQAHRQNVSSLFLPVIESVNPCLILVVRRENIVG
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE4 DAMEVLRKTKNIDYKKPLKVIFVGEDAVDAGGVRKEFFLLIMRELLDPKYGMFRYYEDSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DAMEVLRKTKNIDYKKPLKVIFVGEDAVDAGGVRKEFFLLIMRELLDPKYGMFRYYEDSR
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE4 LIWFSDKTFEDSDLFHLIGVICGLAIYNCTIVDLHFPLALYKKLLKKKPSLDDLKELMPD
:::::::
NP_001 LIWFSDK-----------------------------------------------------
850 860 870 880 890 900
pF1KE4 VGRSMQQLLDYPEDDIEETFCLNFTITVENFGATEVKELVLNGADTAVNKQNRQEFVDAY
:::::::::::::::::::::::::::::::::::
NP_001 -------------------------ITVENFGATEVKELVLNGADTAVNKQNRQEFVDAY
790 800 810 820
910 920 930 940 950 960
pF1KE4 VDYIFNKSVASLFDAFHAGFHKVCGGKVLLLFQPNELQAMVIGNTNYDWKELEKNTEYKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VDYIFNKSVASLFDAFHAGFHKVCGGKVLLLFQPNELQAMVIGNTNYDWKELEKNTEYKG
830 840 850 860 870 880
970 980 990 1000 1010 1020
pF1KE4 EYWAEHPTIKIFWEVFHELPLEKKKQFLLFLTGSDRIPILGMKSLKLVIQSTGGGEEYLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EYWAEHPTIKIFWEVFHELPLEKKKQFLLFLTGSDRIPILGMKSLKLVIQSTGGGEEYLP
890 900 910 920 930 940
1030 1040 1050
pF1KE4 VSHTCFNLLDLPKYTEKETLRSKLIQAIDHNEGFSLI
:::::::::::::::::::::::::::::::::::::
NP_001 VSHTCFNLLDLPKYTEKETLRSKLIQAIDHNEGFSLI
950 960 970
>>NP_001265115 (OMIM: 609248) probable E3 ubiquitin-prot (794 aa)
initn: 5295 init1: 2694 opt: 5283 Z-score: 6158.9 bits: 1150.8 E(85289): 0
Smith-Waterman score: 5283; 99.0% identity (99.0% similar) in 798 aa overlap (260-1057:5-794)
230 240 250 260 270 280
pF1KE4 RYVPNLLKSLRSQKIVYICCGEDHTAALTKEGGVFTFGAGGYGQLGHNSTSHEINPRKVF
::::::::::::::::::::::::::::::
NP_001 MMKMEGGVFTFGAGGYGQLGHNSTSHEINPRKVF
10 20 30
290 300 310 320 330 340
pF1KE4 ELMGSIVTEIACGRQHTSAFVPSSGRIYSFGLGGNGQLGTGSTSNRKSPFTVKGNWYPYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELMGSIVTEIACGRQHTSAFVPSSGRIYSFGLGGNGQLGTGSTSNRKSPFTVKGNWYPYN
40 50 60 70 80 90
350 360 370 380 390 400
pF1KE4 GQCLPDIDSEEYFCVKRIFSGGDQSFSHYSSPQNCGPPDDFRCPNPTKQIWTVNEALIQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GQCLPDIDSEEYFCVKRIFSGGDQSFSHYSSPQNCGPPDDFRCPNPTKQIWTVNEALIQK
100 110 120 130 140 150
410 420 430 440 450 460
pF1KE4 WLSYPSGRFPVEIANEIDGTFSSSGCLNGSFLAVSNDDHYRTGTRFSGVDMNAARLLFHK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WLSYPSGRFPVEIANEIDGTFSSSGCLNGSFLAVSNDDHYRTGTRFSGVDMNAARLLFHK
160 170 180 190 200 210
470 480 490 500 510 520
pF1KE4 LIQPDHPQISQQVAASLEKNLIPKLTSSLPDVEALRFYLTLPECPLMSDSNNFTTIAIPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LIQPDHPQISQQVAASLEKNLIPKLTSSLPDVEALRFYLTLPECPLMSDSNNFTTIAIPF
220 230 240 250 260 270
530 540 550 560 570 580
pF1KE4 GTALVNLEKAPLKVLENWWSVLEPPLFLKIVELFKEVVVHLLKLYKIGIPPSERRIFNSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GTALVNLEKAPLKVLENWWSVLEPPLFLKIVELFKEVVVHLLKLYKIGIPPSERRIFNSF
280 290 300 310 320 330
590 600 610 620 630 640
pF1KE4 LHTALKVLEILHRVNEKMGQIIQYDKFYIHEVQELIDIRNDYINWVQQQAYGMDVNHGLT
:::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LHTALKVLEILHRVNEKMGQIIQYDKFYIHEVQELIDIRNDYINWVQQQAYGM-------
340 350 360 370 380
650 660 670 680 690 700
pF1KE4 ELADIPVTICTYPFVFDAQAKTTLLQTDAVLQMQMAIDQAHRQNVSSLFLPVIESVNPCL
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 -LADIPVTICTYPFVFDAQAKTTLLQTDAVLQMQMAIDQAHRQNVSSLFLPVIESVNPCL
390 400 410 420 430 440
710 720 730 740 750 760
pF1KE4 ILVVRRENIVGDAMEVLRKTKNIDYKKPLKVIFVGEDAVDAGGVRKEFFLLIMRELLDPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ILVVRRENIVGDAMEVLRKTKNIDYKKPLKVIFVGEDAVDAGGVRKEFFLLIMRELLDPK
450 460 470 480 490 500
770 780 790 800 810 820
pF1KE4 YGMFRYYEDSRLIWFSDKTFEDSDLFHLIGVICGLAIYNCTIVDLHFPLALYKKLLKKKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YGMFRYYEDSRLIWFSDKTFEDSDLFHLIGVICGLAIYNCTIVDLHFPLALYKKLLKKKP
510 520 530 540 550 560
830 840 850 860 870 880
pF1KE4 SLDDLKELMPDVGRSMQQLLDYPEDDIEETFCLNFTITVENFGATEVKELVLNGADTAVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLDDLKELMPDVGRSMQQLLDYPEDDIEETFCLNFTITVENFGATEVKELVLNGADTAVN
570 580 590 600 610 620
890 900 910 920 930 940
pF1KE4 KQNRQEFVDAYVDYIFNKSVASLFDAFHAGFHKVCGGKVLLLFQPNELQAMVIGNTNYDW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KQNRQEFVDAYVDYIFNKSVASLFDAFHAGFHKVCGGKVLLLFQPNELQAMVIGNTNYDW
630 640 650 660 670 680
950 960 970 980 990 1000
pF1KE4 KELEKNTEYKGEYWAEHPTIKIFWEVFHELPLEKKKQFLLFLTGSDRIPILGMKSLKLVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KELEKNTEYKGEYWAEHPTIKIFWEVFHELPLEKKKQFLLFLTGSDRIPILGMKSLKLVI
690 700 710 720 730 740
1010 1020 1030 1040 1050
pF1KE4 QSTGGGEEYLPVSHTCFNLLDLPKYTEKETLRSKLIQAIDHNEGFSLI
::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QSTGGGEEYLPVSHTCFNLLDLPKYTEKETLRSKLIQAIDHNEGFSLI
750 760 770 780 790
>>NP_055421 (OMIM: 605200) probable E3 ubiquitin-protein (1050 aa)
initn: 3818 init1: 2042 opt: 3972 Z-score: 4627.6 bits: 867.9 E(85289): 0
Smith-Waterman score: 3972; 56.0% identity (78.7% similar) in 1057 aa overlap (1-1056:1-1049)
10 20 30 40 50 60
pF1KE4 MLCWGNASFGQLGLGGIDEEIVLEPRKSDFFINKRVRDVGCGLRHTVFVLDDGTVYTCGC
::::: :.:: :.. . :: ::. :. .. :..:.:: :.::.:.:: :::::
NP_055 MLCWGYWSLGQPGISTNLQGIVAEPQVCGFISDRSVKEVACGGNHSVFLLEDGEVYTCGL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 NDLGQLGHEKSRKKPEQVVALDAQNIVAVSCGEAHTLALNDKGQVYAWGLDSDGQLGLVG
: ::::::. .::::. :: :.:. :.:::.:.:::.:.::...:: :::::::.
NP_055 NTKGQLGHEREGNKPEQIGALADQHIIHVACGESHSLALSDRGQLFSWGAGSDGQLGLMT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 SEECIRVPRNIKSLSDIQIVQVACGYYHSLALSKASEVFCWGQNKYGQLGLGTDCKKQTS
.:. . ::: :..:.. :.::.:: .: :::. .. : ::.:..:::::: . .:.:
NP_055 TEDSVAVPRLIQKLNQQTILQVSCGNWHCLALAADGQFFTWGKNSHGQLGLGKEFPSQAS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 PQLLKSLLGIPFMQVAAGGAHSFVLTLSGAIFGWGRNKFGQLGLNDENDRYVPNLLKSLR
:: ..:: :::. ::::::::::.:.::::.:::: :. :::::.::.:: : .: ::
NP_055 PQRVRSLEGIPLAQVAAGGAHSFALSLSGAVFGWGMNNAGQLGLSDEKDRESPCHVKLLR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 SQKIVYICCGEDHTAALTKEGGVFTFGAGGYGQLGHNSTSHEINPRKVFELMGSIVTEIA
.::.::: :::.:::.::: :::::::::. :::::.: . :.:::.:.::::: ::.::
NP_055 TQKVVYISCGEEHTAVLTKSGGVFTFGAGSCGQLGHDSMNDEVNPRRVLELMGSEVTQIA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 CGRQHTSAFVPSSGRIYSFGLGGNGQLGTGSTSNRKSPFTVKGNWYPYNGQCLPDIDSEE
:::::: ::::::: ::.:: :. :::::: : : : : ::: : ..:: : .
NP_055 CGRQHTLAFVPSSGLIYAFGCGARGQLGTGHTCNVKCPSPVKGYWAAHSGQLSARADRFK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 YFCVKRIFSGGDQSFSHYSSPQNCGPPDDFRCPNPTKQIWTVNEALIQKWLSYPSGRFPV
: ::.:::::::.: :. .: .: ::: : .. .:. : : . : . .
NP_055 YHIVKQIFSGGDQTFVLCSKYENYSPAVDFRTMNQAHYTSLINDETIAVWRQKLSEHNNA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE4 EIANEIDGTFSSSGCLNGSFLAVSNDDHYRTGTRFSGVDMNAARLLFHKLIQPDHPQISQ
. : . .::..: ::::: . :.:..:. .. :.:.:..:.::.::.. .: .: .
NP_055 NTINGVVQILSSAACWNGSFLEKKIDEHFKTSPKIPGIDLNSTRVLFEKLMNSQHSMILE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE4 QVAASLEKNLIPKLTSSLPDVEALRFYLTLPECPLMSDSNNFTTIAIPFGTALVNLEKAP
:. :.:. :::.:.:: :::::.:.:: ::: ::..::. . :..::.. :.. :. :
NP_055 QILNSFESCLIPQLSSSPPDVEAMRIYLILPEFPLLQDSKYYITLTIPLAMAILRLDTNP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE4 LKVLENWWSVLEPPLFLKIVELFKEVVVHLLKLYKIGIPPSERRIFNSFLHTALKVLEIL
:::.:::: . : :.:.:.:.: .:..::. : . : .::... .:::.:: :
NP_055 SKVLDNWWSQVCPKYFMKLVNLYKGAVLYLLRGRKTFLIPV---LFNNYITAALKLLEKL
550 560 570 580 590
610 620 630 640 650 660
pF1KE4 HRVNEKMGQIIQYDKFYIHEVQELIDIRNDYINWVQQQAYGMDVNHGLTELADIPVTICT
..:: :. .. .:: ::: :...:.::..::. : .:: :: . .. . : ::.:.
NP_055 YKVNLKVKHV-EYDTFYIPEISNLVDIQEDYLMWFLHQA-GMKARPSI--IQDT-VTLCS
600 610 620 630 640 650
670 680 690 700 710
pF1KE4 YPFVFDAQAKTTLLQTDAVLQMQMAIDQAHRQNVSSLF-LPVIESVNPCLILVVRRENIV
:::.::::::: .::::: ::::.:.. :. ::: :. : . . .: :.: :::.:.:
NP_055 YPFIFDAQAKTKMLQTDAELQMQVAVNGANLQNVFMLLTLEPLLARSPFLVLHVRRNNLV
660 670 680 690 700 710
720 730 740 750 760 770
pF1KE4 GDAMEVLRKTKNIDYKKPLKVIFVGEDAVDAGGVRKEFFLLIMRELLDPKYGMFRYYEDS
:::.. : ..:: :::::::: ::.::::::: ::::::...:::.: :::: ::.::
NP_055 GDALRELSIHSDIDLKKPLKVIFDGEEAVDAGGVTKEFFLLLLKELLNPIYGMFTYYQDS
720 730 740 750 760 770
780 790 800 810 820 830
pF1KE4 RLIWFSDKTFEDSDLFHLIGVICGLAIYNCTIVDLHFPLALYKKLLKKKPSLDDLKELMP
:.:::: : . . :::::. ::::::: :.::::::::::::::. ::.:.::::: :
NP_055 NLLWFSDTCFVEHNWFHLIGITCGLAIYNSTVVDLHFPLALYKKLLNVKPGLEDLKELSP
780 790 800 810 820 830
840 850 860 870 880 890
pF1KE4 DVGRSMQQLLDYPEDDIEETFCLNFTITVENFGATEVKELVLNGADTAVNKQNRQEFVDA
:::.:.::::: .:.:::::::::: :..:. : :.:. .: ...: :.::::::::
NP_055 TEGRSLQELLDYPGEDVEETFCLNFTICRESYGVIEQKKLIPGGDNVTVCKDNRQEFVDA
840 850 860 870 880 890
900 910 920 930 940 950
pF1KE4 YVDYIFNKSVASLFDAFHAGFHKVCGGKVLLLFQPNELQAMVIGNTNYDWKELEKNTEYK
::.:.:. :: . :: .:: :::::::: ::::.::.::..::.::.:.:::... ::
NP_055 YVNYVFQISVHEWYTAFSSGFLKVCGGKVLELFQPSELRAMMVGNSNYNWEELEETAIYK
900 910 920 930 940 950
960 970 980 990 1000 1010
pF1KE4 GEYWAEHPTIKIFWEVFHELPLEKKKQFLLFLTGSDRIPILGMKSLKLVIQSTGGGEEYL
:.: : :::.:.:::.:::.::::::.::::::::::::: :: ::..:::::..:::::
NP_055 GDYSATHPTVKLFWETFHEFPLEKKKKFLLFLTGSDRIPIYGMASLQIVIQSTASGEEYL
960 970 980 990 1000 1010
1020 1030 1040 1050
pF1KE4 PVSHTCFNLLDLPKYTEKETLRSKLIQAIDHNEGFSLI
::.:::.::::::::. :: : ..: ::.:. :::::
NP_055 PVAHTCYNLLDLPKYSSKEILSARLTQALDNYEGFSLA
1020 1030 1040 1050
1057 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 01:24:46 2016 done: Sun Nov 6 01:24:48 2016
Total Scan time: 11.700 Total Display time: 0.450
Function used was FASTA [36.3.4 Apr, 2011]