Result of FASTA (omim) for
pFN21AE4230
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE4230, 808 aa
1>>>pF1KE4230 808 - 808 aa - 808 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.5959+/-0.000401; mu= 5.5030+/- 0.025
mean_var=177.6518+/-36.627, 0's: 0 Z-trim(118.4): 76 B-trim: 889 in 1/52
Lambda= 0.096225
statistics sampled from 31169 (31245) to 31169 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.715), E-opt: 0.2 (0.366), width: 16
Scan time: 11.580
The best scores are: opt bits E(85289)
NP_689811 (OMIM: 613337) probable E3 ubiquitin-pro ( 808) 5461 771.0 0
NP_001094345 (OMIM: 613337) probable E3 ubiquitin- ( 808) 5461 771.0 0
XP_011522739 (OMIM: 613337) PREDICTED: probable E3 ( 807) 5444 768.6 0
NP_001275709 (OMIM: 613337) probable E3 ubiquitin- ( 799) 5335 753.5 8.4e-217
XP_005257160 (OMIM: 613337) PREDICTED: probable E3 ( 799) 5335 753.5 8.4e-217
XP_011522738 (OMIM: 613337) PREDICTED: probable E3 ( 825) 5255 742.4 1.9e-213
XP_005257157 (OMIM: 613337) PREDICTED: probable E3 ( 825) 5255 742.4 1.9e-213
XP_005257159 (OMIM: 613337) PREDICTED: probable E3 ( 824) 5238 740.0 9.8e-213
NP_001275708 (OMIM: 613337) probable E3 ubiquitin- ( 846) 4623 654.6 5e-187
XP_005257163 (OMIM: 613337) PREDICTED: probable E3 ( 752) 4417 626.0 1.8e-178
XP_005257155 (OMIM: 613337) PREDICTED: probable E3 ( 862) 4417 626.0 2.1e-178
XP_005257154 (OMIM: 613337) PREDICTED: probable E3 ( 863) 4417 626.0 2.1e-178
XP_005257153 (OMIM: 613337) PREDICTED: probable E3 ( 863) 4417 626.0 2.1e-178
XP_005257152 (OMIM: 613337) PREDICTED: probable E3 ( 863) 4417 626.0 2.1e-178
XP_011522737 (OMIM: 613337) PREDICTED: probable E3 ( 862) 4409 624.9 4.5e-178
XP_016860207 (OMIM: 613334) PREDICTED: E3 ubiquiti ( 691) 594 95.3 1e-18
XP_005246831 (OMIM: 613334) PREDICTED: E3 ubiquiti ( 691) 594 95.3 1e-18
XP_016860210 (OMIM: 613334) PREDICTED: E3 ubiquiti ( 635) 593 95.1 1e-18
NP_001269735 (OMIM: 613334) E3 ubiquitin-protein l ( 635) 593 95.1 1e-18
NP_001269734 (OMIM: 613334) E3 ubiquitin-protein l ( 704) 583 93.7 2.9e-18
NP_073737 (OMIM: 613334) E3 ubiquitin-protein liga ( 704) 583 93.7 2.9e-18
XP_005246830 (OMIM: 613334) PREDICTED: E3 ubiquiti ( 704) 583 93.7 2.9e-18
XP_016860209 (OMIM: 613334) PREDICTED: E3 ubiquiti ( 648) 582 93.6 3e-18
XP_016860208 (OMIM: 613334) PREDICTED: E3 ubiquiti ( 648) 582 93.6 3e-18
NP_001269736 (OMIM: 613334) E3 ubiquitin-protein l ( 666) 582 93.6 3.1e-18
XP_016871383 (OMIM: 613335) PREDICTED: E3 ubiquiti ( 291) 217 42.7 0.0028
XP_011537797 (OMIM: 613335) PREDICTED: E3 ubiquiti ( 291) 217 42.7 0.0028
NP_659458 (OMIM: 613335) E3 ubiquitin-protein liga ( 291) 217 42.7 0.0028
NP_001002266 (OMIM: 613335) E3 ubiquitin-protein l ( 291) 217 42.7 0.0028
XP_006717767 (OMIM: 613335) PREDICTED: E3 ubiquiti ( 573) 218 43.0 0.0044
XP_011537795 (OMIM: 613335) PREDICTED: E3 ubiquiti ( 573) 218 43.0 0.0044
XP_011537794 (OMIM: 613335) PREDICTED: E3 ubiquiti ( 573) 218 43.0 0.0044
NP_001269795 (OMIM: 613335) E3 ubiquitin-protein l ( 573) 218 43.0 0.0044
XP_005271861 (OMIM: 613335) PREDICTED: E3 ubiquiti ( 573) 218 43.0 0.0044
XP_011537796 (OMIM: 613335) PREDICTED: E3 ubiquiti ( 573) 218 43.0 0.0044
XP_016864433 (OMIM: 613297) PREDICTED: E3 ubiquiti ( 460) 210 41.9 0.008
>>NP_689811 (OMIM: 613337) probable E3 ubiquitin-protein (808 aa)
initn: 5461 init1: 5461 opt: 5461 Z-score: 4107.7 bits: 771.0 E(85289): 0
Smith-Waterman score: 5461; 100.0% identity (100.0% similar) in 808 aa overlap (1-808:1-808)
10 20 30 40 50 60
pF1KE4 MLHDARDRQKFFSDVQYLRDMQHKVDSEYQACLRRQEYRRDPNEKKRDQFWGQETSFERS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 MLHDARDRQKFFSDVQYLRDMQHKVDSEYQACLRRQEYRRDPNEKKRDQFWGQETSFERS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 RFSSRSSSKQSSSEEDALTEPRSSIKISAFKCDSKLPAIDQTSVKQKHKSTMTVRKAEKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 RFSSRSSSKQSSSEEDALTEPRSSIKISAFKCDSKLPAIDQTSVKQKHKSTMTVRKAEKV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 DPSEPSPADQAPMVLLRKRKPNLRRFTVSPESHSPRASGDRSRQKQQWPAKVPVPRGADQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 DPSEPSPADQAPMVLLRKRKPNLRRFTVSPESHSPRASGDRSRQKQQWPAKVPVPRGADQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 VVQQEGLMCNTKLKRPNQERRNLVPSSQPMTENAPDRAKKGDPSAPSQSELHPALSQAFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 VVQQEGLMCNTKLKRPNQERRNLVPSSQPMTENAPDRAKKGDPSAPSQSELHPALSQAFQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 GKNSPQVLSEFSGPPLTPTTVGGPRKASFRFRDEDFYSILSLNSRRESDDTEEETQSEEC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 GKNSPQVLSEFSGPPLTPTTVGGPRKASFRFRDEDFYSILSLNSRRESDDTEEETQSEEC
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 LWVGVRSPCSPSHHKRSRFGGTSTPQAKNKNFEENAENCRGHSSRRSEPSHGSLRISNAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 LWVGVRSPCSPSHHKRSRFGGTSTPQAKNKNFEENAENCRGHSSRRSEPSHGSLRISNAM
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 EPATERPSAGQRLSQDPGLPDRESATEKDRGGSENAKKSPLSWDTKSEPRQEVGVNAENV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 EPATERPSAGQRLSQDPGLPDRESATEKDRGGSENAKKSPLSWDTKSEPRQEVGVNAENV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE4 WSDCISVEHRPGTHDSEGYWKDYLNSSQNSLDYFISGRPISPRSSVNSSYNPPASFMHSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 WSDCISVEHRPGTHDSEGYWKDYLNSSQNSLDYFISGRPISPRSSVNSSYNPPASFMHSA
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE4 LRDDIPVDLSMSSTSVHSSDSEGNSGFHVCQPLSPIRNRTPFASAENHNYFPVNSAHEFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 LRDDIPVDLSMSSTSVHSSDSEGNSGFHVCQPLSPIRNRTPFASAENHNYFPVNSAHEFA
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE4 VREAEDTTLTSQPQGAPLYTDLLLNPQGNLSLVDSSSSSPSRMNSEGHLHVSGSLQENTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 VREAEDTTLTSQPQGAPLYTDLLLNPQGNLSLVDSSSSSPSRMNSEGHLHVSGSLQENTP
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE4 FTFFAVSHFPNQNDNGSRMAASGFTDEKETSKIKADPEKLKKLQESLLEEDSEEEGDLCR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 FTFFAVSHFPNQNDNGSRMAASGFTDEKETSKIKADPEKLKKLQESLLEEDSEEEGDLCR
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE4 ICQIAGGSPSNPLLEPCGCVGSLQFVHQECLKKWLKVKITSGADLGAVKTCEMCKQGLLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 ICQIAGGSPSNPLLEPCGCVGSLQFVHQECLKKWLKVKITSGADLGAVKTCEMCKQGLLV
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE4 DLGDFNMIEFYQKHQQSQAQNELMNSGLYLVLLLHLYEQRFAELMRLNHNQVERERLSRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 DLGDFNMIEFYQKHQQSQAQNELMNSGLYLVLLLHLYEQRFAELMRLNHNQVERERLSRN
730 740 750 760 770 780
790 800
pF1KE4 YPQPRTEENENSELGDGNEGSISQSQVV
::::::::::::::::::::::::::::
NP_689 YPQPRTEENENSELGDGNEGSISQSQVV
790 800
>>NP_001094345 (OMIM: 613337) probable E3 ubiquitin-prot (808 aa)
initn: 5461 init1: 5461 opt: 5461 Z-score: 4107.7 bits: 771.0 E(85289): 0
Smith-Waterman score: 5461; 100.0% identity (100.0% similar) in 808 aa overlap (1-808:1-808)
10 20 30 40 50 60
pF1KE4 MLHDARDRQKFFSDVQYLRDMQHKVDSEYQACLRRQEYRRDPNEKKRDQFWGQETSFERS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MLHDARDRQKFFSDVQYLRDMQHKVDSEYQACLRRQEYRRDPNEKKRDQFWGQETSFERS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 RFSSRSSSKQSSSEEDALTEPRSSIKISAFKCDSKLPAIDQTSVKQKHKSTMTVRKAEKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RFSSRSSSKQSSSEEDALTEPRSSIKISAFKCDSKLPAIDQTSVKQKHKSTMTVRKAEKV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 DPSEPSPADQAPMVLLRKRKPNLRRFTVSPESHSPRASGDRSRQKQQWPAKVPVPRGADQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DPSEPSPADQAPMVLLRKRKPNLRRFTVSPESHSPRASGDRSRQKQQWPAKVPVPRGADQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 VVQQEGLMCNTKLKRPNQERRNLVPSSQPMTENAPDRAKKGDPSAPSQSELHPALSQAFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VVQQEGLMCNTKLKRPNQERRNLVPSSQPMTENAPDRAKKGDPSAPSQSELHPALSQAFQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 GKNSPQVLSEFSGPPLTPTTVGGPRKASFRFRDEDFYSILSLNSRRESDDTEEETQSEEC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GKNSPQVLSEFSGPPLTPTTVGGPRKASFRFRDEDFYSILSLNSRRESDDTEEETQSEEC
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 LWVGVRSPCSPSHHKRSRFGGTSTPQAKNKNFEENAENCRGHSSRRSEPSHGSLRISNAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LWVGVRSPCSPSHHKRSRFGGTSTPQAKNKNFEENAENCRGHSSRRSEPSHGSLRISNAM
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 EPATERPSAGQRLSQDPGLPDRESATEKDRGGSENAKKSPLSWDTKSEPRQEVGVNAENV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EPATERPSAGQRLSQDPGLPDRESATEKDRGGSENAKKSPLSWDTKSEPRQEVGVNAENV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE4 WSDCISVEHRPGTHDSEGYWKDYLNSSQNSLDYFISGRPISPRSSVNSSYNPPASFMHSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WSDCISVEHRPGTHDSEGYWKDYLNSSQNSLDYFISGRPISPRSSVNSSYNPPASFMHSA
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE4 LRDDIPVDLSMSSTSVHSSDSEGNSGFHVCQPLSPIRNRTPFASAENHNYFPVNSAHEFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LRDDIPVDLSMSSTSVHSSDSEGNSGFHVCQPLSPIRNRTPFASAENHNYFPVNSAHEFA
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE4 VREAEDTTLTSQPQGAPLYTDLLLNPQGNLSLVDSSSSSPSRMNSEGHLHVSGSLQENTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VREAEDTTLTSQPQGAPLYTDLLLNPQGNLSLVDSSSSSPSRMNSEGHLHVSGSLQENTP
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE4 FTFFAVSHFPNQNDNGSRMAASGFTDEKETSKIKADPEKLKKLQESLLEEDSEEEGDLCR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FTFFAVSHFPNQNDNGSRMAASGFTDEKETSKIKADPEKLKKLQESLLEEDSEEEGDLCR
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE4 ICQIAGGSPSNPLLEPCGCVGSLQFVHQECLKKWLKVKITSGADLGAVKTCEMCKQGLLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ICQIAGGSPSNPLLEPCGCVGSLQFVHQECLKKWLKVKITSGADLGAVKTCEMCKQGLLV
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE4 DLGDFNMIEFYQKHQQSQAQNELMNSGLYLVLLLHLYEQRFAELMRLNHNQVERERLSRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DLGDFNMIEFYQKHQQSQAQNELMNSGLYLVLLLHLYEQRFAELMRLNHNQVERERLSRN
730 740 750 760 770 780
790 800
pF1KE4 YPQPRTEENENSELGDGNEGSISQSQVV
::::::::::::::::::::::::::::
NP_001 YPQPRTEENENSELGDGNEGSISQSQVV
790 800
>>XP_011522739 (OMIM: 613337) PREDICTED: probable E3 ubi (807 aa)
initn: 4610 init1: 4610 opt: 5444 Z-score: 4095.0 bits: 768.6 E(85289): 0
Smith-Waterman score: 5444; 99.9% identity (99.9% similar) in 808 aa overlap (1-808:1-807)
10 20 30 40 50 60
pF1KE4 MLHDARDRQKFFSDVQYLRDMQHKVDSEYQACLRRQEYRRDPNEKKRDQFWGQETSFERS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MLHDARDRQKFFSDVQYLRDMQHKVDSEYQACLRRQEYRRDPNEKKRDQFWGQETSFERS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 RFSSRSSSKQSSSEEDALTEPRSSIKISAFKCDSKLPAIDQTSVKQKHKSTMTVRKAEKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RFSSRSSSKQSSSEEDALTEPRSSIKISAFKCDSKLPAIDQTSVKQKHKSTMTVRKAEKV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 DPSEPSPADQAPMVLLRKRKPNLRRFTVSPESHSPRASGDRSRQKQQWPAKVPVPRGADQ
::::::: ::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DPSEPSP-DQAPMVLLRKRKPNLRRFTVSPESHSPRASGDRSRQKQQWPAKVPVPRGADQ
130 140 150 160 170
190 200 210 220 230 240
pF1KE4 VVQQEGLMCNTKLKRPNQERRNLVPSSQPMTENAPDRAKKGDPSAPSQSELHPALSQAFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VVQQEGLMCNTKLKRPNQERRNLVPSSQPMTENAPDRAKKGDPSAPSQSELHPALSQAFQ
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE4 GKNSPQVLSEFSGPPLTPTTVGGPRKASFRFRDEDFYSILSLNSRRESDDTEEETQSEEC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GKNSPQVLSEFSGPPLTPTTVGGPRKASFRFRDEDFYSILSLNSRRESDDTEEETQSEEC
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE4 LWVGVRSPCSPSHHKRSRFGGTSTPQAKNKNFEENAENCRGHSSRRSEPSHGSLRISNAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LWVGVRSPCSPSHHKRSRFGGTSTPQAKNKNFEENAENCRGHSSRRSEPSHGSLRISNAM
300 310 320 330 340 350
370 380 390 400 410 420
pF1KE4 EPATERPSAGQRLSQDPGLPDRESATEKDRGGSENAKKSPLSWDTKSEPRQEVGVNAENV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EPATERPSAGQRLSQDPGLPDRESATEKDRGGSENAKKSPLSWDTKSEPRQEVGVNAENV
360 370 380 390 400 410
430 440 450 460 470 480
pF1KE4 WSDCISVEHRPGTHDSEGYWKDYLNSSQNSLDYFISGRPISPRSSVNSSYNPPASFMHSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WSDCISVEHRPGTHDSEGYWKDYLNSSQNSLDYFISGRPISPRSSVNSSYNPPASFMHSA
420 430 440 450 460 470
490 500 510 520 530 540
pF1KE4 LRDDIPVDLSMSSTSVHSSDSEGNSGFHVCQPLSPIRNRTPFASAENHNYFPVNSAHEFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRDDIPVDLSMSSTSVHSSDSEGNSGFHVCQPLSPIRNRTPFASAENHNYFPVNSAHEFA
480 490 500 510 520 530
550 560 570 580 590 600
pF1KE4 VREAEDTTLTSQPQGAPLYTDLLLNPQGNLSLVDSSSSSPSRMNSEGHLHVSGSLQENTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VREAEDTTLTSQPQGAPLYTDLLLNPQGNLSLVDSSSSSPSRMNSEGHLHVSGSLQENTP
540 550 560 570 580 590
610 620 630 640 650 660
pF1KE4 FTFFAVSHFPNQNDNGSRMAASGFTDEKETSKIKADPEKLKKLQESLLEEDSEEEGDLCR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FTFFAVSHFPNQNDNGSRMAASGFTDEKETSKIKADPEKLKKLQESLLEEDSEEEGDLCR
600 610 620 630 640 650
670 680 690 700 710 720
pF1KE4 ICQIAGGSPSNPLLEPCGCVGSLQFVHQECLKKWLKVKITSGADLGAVKTCEMCKQGLLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ICQIAGGSPSNPLLEPCGCVGSLQFVHQECLKKWLKVKITSGADLGAVKTCEMCKQGLLV
660 670 680 690 700 710
730 740 750 760 770 780
pF1KE4 DLGDFNMIEFYQKHQQSQAQNELMNSGLYLVLLLHLYEQRFAELMRLNHNQVERERLSRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DLGDFNMIEFYQKHQQSQAQNELMNSGLYLVLLLHLYEQRFAELMRLNHNQVERERLSRN
720 730 740 750 760 770
790 800
pF1KE4 YPQPRTEENENSELGDGNEGSISQSQVV
::::::::::::::::::::::::::::
XP_011 YPQPRTEENENSELGDGNEGSISQSQVV
780 790 800
>>NP_001275709 (OMIM: 613337) probable E3 ubiquitin-prot (799 aa)
initn: 5337 init1: 4499 opt: 5335 Z-score: 4013.3 bits: 753.5 E(85289): 8.4e-217
Smith-Waterman score: 5335; 99.4% identity (99.5% similar) in 795 aa overlap (1-795:1-794)
10 20 30 40 50 60
pF1KE4 MLHDARDRQKFFSDVQYLRDMQHKVDSEYQACLRRQEYRRDPNEKKRDQFWGQETSFERS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MLHDARDRQKFFSDVQYLRDMQHKVDSEYQACLRRQEYRRDPNEKKRDQFWGQETSFERS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 RFSSRSSSKQSSSEEDALTEPRSSIKISAFKCDSKLPAIDQTSVKQKHKSTMTVRKAEKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RFSSRSSSKQSSSEEDALTEPRSSIKISAFKCDSKLPAIDQTSVKQKHKSTMTVRKAEKV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 DPSEPSPADQAPMVLLRKRKPNLRRFTVSPESHSPRASGDRSRQKQQWPAKVPVPRGADQ
::::::: ::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DPSEPSP-DQAPMVLLRKRKPNLRRFTVSPESHSPRASGDRSRQKQQWPAKVPVPRGADQ
130 140 150 160 170
190 200 210 220 230 240
pF1KE4 VVQQEGLMCNTKLKRPNQERRNLVPSSQPMTENAPDRAKKGDPSAPSQSELHPALSQAFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VVQQEGLMCNTKLKRPNQERRNLVPSSQPMTENAPDRAKKGDPSAPSQSELHPALSQAFQ
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE4 GKNSPQVLSEFSGPPLTPTTVGGPRKASFRFRDEDFYSILSLNSRRESDDTEEETQSEEC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GKNSPQVLSEFSGPPLTPTTVGGPRKASFRFRDEDFYSILSLNSRRESDDTEEETQSEEC
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE4 LWVGVRSPCSPSHHKRSRFGGTSTPQAKNKNFEENAENCRGHSSRRSEPSHGSLRISNAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LWVGVRSPCSPSHHKRSRFGGTSTPQAKNKNFEENAENCRGHSSRRSEPSHGSLRISNAM
300 310 320 330 340 350
370 380 390 400 410 420
pF1KE4 EPATERPSAGQRLSQDPGLPDRESATEKDRGGSENAKKSPLSWDTKSEPRQEVGVNAENV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EPATERPSAGQRLSQDPGLPDRESATEKDRGGSENAKKSPLSWDTKSEPRQEVGVNAENV
360 370 380 390 400 410
430 440 450 460 470 480
pF1KE4 WSDCISVEHRPGTHDSEGYWKDYLNSSQNSLDYFISGRPISPRSSVNSSYNPPASFMHSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WSDCISVEHRPGTHDSEGYWKDYLNSSQNSLDYFISGRPISPRSSVNSSYNPPASFMHSA
420 430 440 450 460 470
490 500 510 520 530 540
pF1KE4 LRDDIPVDLSMSSTSVHSSDSEGNSGFHVCQPLSPIRNRTPFASAENHNYFPVNSAHEFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LRDDIPVDLSMSSTSVHSSDSEGNSGFHVCQPLSPIRNRTPFASAENHNYFPVNSAHEFA
480 490 500 510 520 530
550 560 570 580 590 600
pF1KE4 VREAEDTTLTSQPQGAPLYTDLLLNPQGNLSLVDSSSSSPSRMNSEGHLHVSGSLQENTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VREAEDTTLTSQPQGAPLYTDLLLNPQGNLSLVDSSSSSPSRMNSEGHLHVSGSLQENTP
540 550 560 570 580 590
610 620 630 640 650 660
pF1KE4 FTFFAVSHFPNQNDNGSRMAASGFTDEKETSKIKADPEKLKKLQESLLEEDSEEEGDLCR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FTFFAVSHFPNQNDNGSRMAASGFTDEKETSKIKADPEKLKKLQESLLEEDSEEEGDLCR
600 610 620 630 640 650
670 680 690 700 710 720
pF1KE4 ICQIAGGSPSNPLLEPCGCVGSLQFVHQECLKKWLKVKITSGADLGAVKTCEMCKQGLLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ICQIAGGSPSNPLLEPCGCVGSLQFVHQECLKKWLKVKITSGADLGAVKTCEMCKQGLLV
660 670 680 690 700 710
730 740 750 760 770 780
pF1KE4 DLGDFNMIEFYQKHQQSQAQNELMNSGLYLVLLLHLYEQRFAELMRLNHNQVERERLSRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DLGDFNMIEFYQKHQQSQAQNELMNSGLYLVLLLHLYEQRFAELMRLNHNQVERERLSRN
720 730 740 750 760 770
790 800
pF1KE4 YPQPRTEENENSELGDGNEGSISQSQVV
::::::::::. :
NP_001 YPQPRTEENESRFWGPVLPF
780 790
>>XP_005257160 (OMIM: 613337) PREDICTED: probable E3 ubi (799 aa)
initn: 5337 init1: 4499 opt: 5335 Z-score: 4013.3 bits: 753.5 E(85289): 8.4e-217
Smith-Waterman score: 5335; 99.4% identity (99.5% similar) in 795 aa overlap (1-795:1-794)
10 20 30 40 50 60
pF1KE4 MLHDARDRQKFFSDVQYLRDMQHKVDSEYQACLRRQEYRRDPNEKKRDQFWGQETSFERS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MLHDARDRQKFFSDVQYLRDMQHKVDSEYQACLRRQEYRRDPNEKKRDQFWGQETSFERS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 RFSSRSSSKQSSSEEDALTEPRSSIKISAFKCDSKLPAIDQTSVKQKHKSTMTVRKAEKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RFSSRSSSKQSSSEEDALTEPRSSIKISAFKCDSKLPAIDQTSVKQKHKSTMTVRKAEKV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 DPSEPSPADQAPMVLLRKRKPNLRRFTVSPESHSPRASGDRSRQKQQWPAKVPVPRGADQ
::::::: ::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DPSEPSP-DQAPMVLLRKRKPNLRRFTVSPESHSPRASGDRSRQKQQWPAKVPVPRGADQ
130 140 150 160 170
190 200 210 220 230 240
pF1KE4 VVQQEGLMCNTKLKRPNQERRNLVPSSQPMTENAPDRAKKGDPSAPSQSELHPALSQAFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VVQQEGLMCNTKLKRPNQERRNLVPSSQPMTENAPDRAKKGDPSAPSQSELHPALSQAFQ
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE4 GKNSPQVLSEFSGPPLTPTTVGGPRKASFRFRDEDFYSILSLNSRRESDDTEEETQSEEC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GKNSPQVLSEFSGPPLTPTTVGGPRKASFRFRDEDFYSILSLNSRRESDDTEEETQSEEC
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE4 LWVGVRSPCSPSHHKRSRFGGTSTPQAKNKNFEENAENCRGHSSRRSEPSHGSLRISNAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LWVGVRSPCSPSHHKRSRFGGTSTPQAKNKNFEENAENCRGHSSRRSEPSHGSLRISNAM
300 310 320 330 340 350
370 380 390 400 410 420
pF1KE4 EPATERPSAGQRLSQDPGLPDRESATEKDRGGSENAKKSPLSWDTKSEPRQEVGVNAENV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EPATERPSAGQRLSQDPGLPDRESATEKDRGGSENAKKSPLSWDTKSEPRQEVGVNAENV
360 370 380 390 400 410
430 440 450 460 470 480
pF1KE4 WSDCISVEHRPGTHDSEGYWKDYLNSSQNSLDYFISGRPISPRSSVNSSYNPPASFMHSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 WSDCISVEHRPGTHDSEGYWKDYLNSSQNSLDYFISGRPISPRSSVNSSYNPPASFMHSA
420 430 440 450 460 470
490 500 510 520 530 540
pF1KE4 LRDDIPVDLSMSSTSVHSSDSEGNSGFHVCQPLSPIRNRTPFASAENHNYFPVNSAHEFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LRDDIPVDLSMSSTSVHSSDSEGNSGFHVCQPLSPIRNRTPFASAENHNYFPVNSAHEFA
480 490 500 510 520 530
550 560 570 580 590 600
pF1KE4 VREAEDTTLTSQPQGAPLYTDLLLNPQGNLSLVDSSSSSPSRMNSEGHLHVSGSLQENTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VREAEDTTLTSQPQGAPLYTDLLLNPQGNLSLVDSSSSSPSRMNSEGHLHVSGSLQENTP
540 550 560 570 580 590
610 620 630 640 650 660
pF1KE4 FTFFAVSHFPNQNDNGSRMAASGFTDEKETSKIKADPEKLKKLQESLLEEDSEEEGDLCR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FTFFAVSHFPNQNDNGSRMAASGFTDEKETSKIKADPEKLKKLQESLLEEDSEEEGDLCR
600 610 620 630 640 650
670 680 690 700 710 720
pF1KE4 ICQIAGGSPSNPLLEPCGCVGSLQFVHQECLKKWLKVKITSGADLGAVKTCEMCKQGLLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ICQIAGGSPSNPLLEPCGCVGSLQFVHQECLKKWLKVKITSGADLGAVKTCEMCKQGLLV
660 670 680 690 700 710
730 740 750 760 770 780
pF1KE4 DLGDFNMIEFYQKHQQSQAQNELMNSGLYLVLLLHLYEQRFAELMRLNHNQVERERLSRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DLGDFNMIEFYQKHQQSQAQNELMNSGLYLVLLLHLYEQRFAELMRLNHNQVERERLSRN
720 730 740 750 760 770
790 800
pF1KE4 YPQPRTEENENSELGDGNEGSISQSQVV
::::::::::. :
XP_005 YPQPRTEENESRFWGPVLPF
780 790
>>XP_011522738 (OMIM: 613337) PREDICTED: probable E3 ubi (825 aa)
initn: 5286 init1: 5255 opt: 5255 Z-score: 3953.0 bits: 742.4 E(85289): 1.9e-213
Smith-Waterman score: 5255; 99.9% identity (100.0% similar) in 777 aa overlap (1-777:1-777)
10 20 30 40 50 60
pF1KE4 MLHDARDRQKFFSDVQYLRDMQHKVDSEYQACLRRQEYRRDPNEKKRDQFWGQETSFERS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MLHDARDRQKFFSDVQYLRDMQHKVDSEYQACLRRQEYRRDPNEKKRDQFWGQETSFERS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 RFSSRSSSKQSSSEEDALTEPRSSIKISAFKCDSKLPAIDQTSVKQKHKSTMTVRKAEKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RFSSRSSSKQSSSEEDALTEPRSSIKISAFKCDSKLPAIDQTSVKQKHKSTMTVRKAEKV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 DPSEPSPADQAPMVLLRKRKPNLRRFTVSPESHSPRASGDRSRQKQQWPAKVPVPRGADQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DPSEPSPADQAPMVLLRKRKPNLRRFTVSPESHSPRASGDRSRQKQQWPAKVPVPRGADQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 VVQQEGLMCNTKLKRPNQERRNLVPSSQPMTENAPDRAKKGDPSAPSQSELHPALSQAFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VVQQEGLMCNTKLKRPNQERRNLVPSSQPMTENAPDRAKKGDPSAPSQSELHPALSQAFQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 GKNSPQVLSEFSGPPLTPTTVGGPRKASFRFRDEDFYSILSLNSRRESDDTEEETQSEEC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GKNSPQVLSEFSGPPLTPTTVGGPRKASFRFRDEDFYSILSLNSRRESDDTEEETQSEEC
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 LWVGVRSPCSPSHHKRSRFGGTSTPQAKNKNFEENAENCRGHSSRRSEPSHGSLRISNAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LWVGVRSPCSPSHHKRSRFGGTSTPQAKNKNFEENAENCRGHSSRRSEPSHGSLRISNAM
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 EPATERPSAGQRLSQDPGLPDRESATEKDRGGSENAKKSPLSWDTKSEPRQEVGVNAENV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EPATERPSAGQRLSQDPGLPDRESATEKDRGGSENAKKSPLSWDTKSEPRQEVGVNAENV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE4 WSDCISVEHRPGTHDSEGYWKDYLNSSQNSLDYFISGRPISPRSSVNSSYNPPASFMHSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WSDCISVEHRPGTHDSEGYWKDYLNSSQNSLDYFISGRPISPRSSVNSSYNPPASFMHSA
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE4 LRDDIPVDLSMSSTSVHSSDSEGNSGFHVCQPLSPIRNRTPFASAENHNYFPVNSAHEFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRDDIPVDLSMSSTSVHSSDSEGNSGFHVCQPLSPIRNRTPFASAENHNYFPVNSAHEFA
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE4 VREAEDTTLTSQPQGAPLYTDLLLNPQGNLSLVDSSSSSPSRMNSEGHLHVSGSLQENTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VREAEDTTLTSQPQGAPLYTDLLLNPQGNLSLVDSSSSSPSRMNSEGHLHVSGSLQENTP
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE4 FTFFAVSHFPNQNDNGSRMAASGFTDEKETSKIKADPEKLKKLQESLLEEDSEEEGDLCR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FTFFAVSHFPNQNDNGSRMAASGFTDEKETSKIKADPEKLKKLQESLLEEDSEEEGDLCR
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE4 ICQIAGGSPSNPLLEPCGCVGSLQFVHQECLKKWLKVKITSGADLGAVKTCEMCKQGLLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ICQIAGGSPSNPLLEPCGCVGSLQFVHQECLKKWLKVKITSGADLGAVKTCEMCKQGLLV
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE4 DLGDFNMIEFYQKHQQSQAQNELMNSGLYLVLLLHLYEQRFAELMRLNHNQVERERLSRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::.
XP_011 DLGDFNMIEFYQKHQQSQAQNELMNSGLYLVLLLHLYEQRFAELMRLNHNQVERERIRSW
730 740 750 760 770 780
790 800
pF1KE4 YPQPRTEENENSELGDGNEGSISQSQVV
XP_011 EMEMKAAFLKARSSSKEANCGARRRPLPPALLSTSPSASLPPPLY
790 800 810 820
>>XP_005257157 (OMIM: 613337) PREDICTED: probable E3 ubi (825 aa)
initn: 5286 init1: 5255 opt: 5255 Z-score: 3953.0 bits: 742.4 E(85289): 1.9e-213
Smith-Waterman score: 5255; 99.9% identity (100.0% similar) in 777 aa overlap (1-777:1-777)
10 20 30 40 50 60
pF1KE4 MLHDARDRQKFFSDVQYLRDMQHKVDSEYQACLRRQEYRRDPNEKKRDQFWGQETSFERS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MLHDARDRQKFFSDVQYLRDMQHKVDSEYQACLRRQEYRRDPNEKKRDQFWGQETSFERS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 RFSSRSSSKQSSSEEDALTEPRSSIKISAFKCDSKLPAIDQTSVKQKHKSTMTVRKAEKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RFSSRSSSKQSSSEEDALTEPRSSIKISAFKCDSKLPAIDQTSVKQKHKSTMTVRKAEKV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 DPSEPSPADQAPMVLLRKRKPNLRRFTVSPESHSPRASGDRSRQKQQWPAKVPVPRGADQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DPSEPSPADQAPMVLLRKRKPNLRRFTVSPESHSPRASGDRSRQKQQWPAKVPVPRGADQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 VVQQEGLMCNTKLKRPNQERRNLVPSSQPMTENAPDRAKKGDPSAPSQSELHPALSQAFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VVQQEGLMCNTKLKRPNQERRNLVPSSQPMTENAPDRAKKGDPSAPSQSELHPALSQAFQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 GKNSPQVLSEFSGPPLTPTTVGGPRKASFRFRDEDFYSILSLNSRRESDDTEEETQSEEC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GKNSPQVLSEFSGPPLTPTTVGGPRKASFRFRDEDFYSILSLNSRRESDDTEEETQSEEC
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 LWVGVRSPCSPSHHKRSRFGGTSTPQAKNKNFEENAENCRGHSSRRSEPSHGSLRISNAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LWVGVRSPCSPSHHKRSRFGGTSTPQAKNKNFEENAENCRGHSSRRSEPSHGSLRISNAM
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 EPATERPSAGQRLSQDPGLPDRESATEKDRGGSENAKKSPLSWDTKSEPRQEVGVNAENV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EPATERPSAGQRLSQDPGLPDRESATEKDRGGSENAKKSPLSWDTKSEPRQEVGVNAENV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE4 WSDCISVEHRPGTHDSEGYWKDYLNSSQNSLDYFISGRPISPRSSVNSSYNPPASFMHSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 WSDCISVEHRPGTHDSEGYWKDYLNSSQNSLDYFISGRPISPRSSVNSSYNPPASFMHSA
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE4 LRDDIPVDLSMSSTSVHSSDSEGNSGFHVCQPLSPIRNRTPFASAENHNYFPVNSAHEFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LRDDIPVDLSMSSTSVHSSDSEGNSGFHVCQPLSPIRNRTPFASAENHNYFPVNSAHEFA
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE4 VREAEDTTLTSQPQGAPLYTDLLLNPQGNLSLVDSSSSSPSRMNSEGHLHVSGSLQENTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VREAEDTTLTSQPQGAPLYTDLLLNPQGNLSLVDSSSSSPSRMNSEGHLHVSGSLQENTP
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE4 FTFFAVSHFPNQNDNGSRMAASGFTDEKETSKIKADPEKLKKLQESLLEEDSEEEGDLCR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FTFFAVSHFPNQNDNGSRMAASGFTDEKETSKIKADPEKLKKLQESLLEEDSEEEGDLCR
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE4 ICQIAGGSPSNPLLEPCGCVGSLQFVHQECLKKWLKVKITSGADLGAVKTCEMCKQGLLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ICQIAGGSPSNPLLEPCGCVGSLQFVHQECLKKWLKVKITSGADLGAVKTCEMCKQGLLV
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE4 DLGDFNMIEFYQKHQQSQAQNELMNSGLYLVLLLHLYEQRFAELMRLNHNQVERERLSRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::.
XP_005 DLGDFNMIEFYQKHQQSQAQNELMNSGLYLVLLLHLYEQRFAELMRLNHNQVERERIRSW
730 740 750 760 770 780
790 800
pF1KE4 YPQPRTEENENSELGDGNEGSISQSQVV
XP_005 EMEMKAAFLKARSSSKEANCGARRRPLPPALLSTSPSASLPPPLY
790 800 810 820
>>XP_005257159 (OMIM: 613337) PREDICTED: probable E3 ubi (824 aa)
initn: 5242 init1: 4404 opt: 5238 Z-score: 3940.3 bits: 740.0 E(85289): 9.8e-213
Smith-Waterman score: 5238; 99.7% identity (99.9% similar) in 777 aa overlap (1-777:1-776)
10 20 30 40 50 60
pF1KE4 MLHDARDRQKFFSDVQYLRDMQHKVDSEYQACLRRQEYRRDPNEKKRDQFWGQETSFERS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MLHDARDRQKFFSDVQYLRDMQHKVDSEYQACLRRQEYRRDPNEKKRDQFWGQETSFERS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 RFSSRSSSKQSSSEEDALTEPRSSIKISAFKCDSKLPAIDQTSVKQKHKSTMTVRKAEKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RFSSRSSSKQSSSEEDALTEPRSSIKISAFKCDSKLPAIDQTSVKQKHKSTMTVRKAEKV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 DPSEPSPADQAPMVLLRKRKPNLRRFTVSPESHSPRASGDRSRQKQQWPAKVPVPRGADQ
::::::: ::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DPSEPSP-DQAPMVLLRKRKPNLRRFTVSPESHSPRASGDRSRQKQQWPAKVPVPRGADQ
130 140 150 160 170
190 200 210 220 230 240
pF1KE4 VVQQEGLMCNTKLKRPNQERRNLVPSSQPMTENAPDRAKKGDPSAPSQSELHPALSQAFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VVQQEGLMCNTKLKRPNQERRNLVPSSQPMTENAPDRAKKGDPSAPSQSELHPALSQAFQ
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE4 GKNSPQVLSEFSGPPLTPTTVGGPRKASFRFRDEDFYSILSLNSRRESDDTEEETQSEEC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GKNSPQVLSEFSGPPLTPTTVGGPRKASFRFRDEDFYSILSLNSRRESDDTEEETQSEEC
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE4 LWVGVRSPCSPSHHKRSRFGGTSTPQAKNKNFEENAENCRGHSSRRSEPSHGSLRISNAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LWVGVRSPCSPSHHKRSRFGGTSTPQAKNKNFEENAENCRGHSSRRSEPSHGSLRISNAM
300 310 320 330 340 350
370 380 390 400 410 420
pF1KE4 EPATERPSAGQRLSQDPGLPDRESATEKDRGGSENAKKSPLSWDTKSEPRQEVGVNAENV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EPATERPSAGQRLSQDPGLPDRESATEKDRGGSENAKKSPLSWDTKSEPRQEVGVNAENV
360 370 380 390 400 410
430 440 450 460 470 480
pF1KE4 WSDCISVEHRPGTHDSEGYWKDYLNSSQNSLDYFISGRPISPRSSVNSSYNPPASFMHSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 WSDCISVEHRPGTHDSEGYWKDYLNSSQNSLDYFISGRPISPRSSVNSSYNPPASFMHSA
420 430 440 450 460 470
490 500 510 520 530 540
pF1KE4 LRDDIPVDLSMSSTSVHSSDSEGNSGFHVCQPLSPIRNRTPFASAENHNYFPVNSAHEFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LRDDIPVDLSMSSTSVHSSDSEGNSGFHVCQPLSPIRNRTPFASAENHNYFPVNSAHEFA
480 490 500 510 520 530
550 560 570 580 590 600
pF1KE4 VREAEDTTLTSQPQGAPLYTDLLLNPQGNLSLVDSSSSSPSRMNSEGHLHVSGSLQENTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VREAEDTTLTSQPQGAPLYTDLLLNPQGNLSLVDSSSSSPSRMNSEGHLHVSGSLQENTP
540 550 560 570 580 590
610 620 630 640 650 660
pF1KE4 FTFFAVSHFPNQNDNGSRMAASGFTDEKETSKIKADPEKLKKLQESLLEEDSEEEGDLCR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FTFFAVSHFPNQNDNGSRMAASGFTDEKETSKIKADPEKLKKLQESLLEEDSEEEGDLCR
600 610 620 630 640 650
670 680 690 700 710 720
pF1KE4 ICQIAGGSPSNPLLEPCGCVGSLQFVHQECLKKWLKVKITSGADLGAVKTCEMCKQGLLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ICQIAGGSPSNPLLEPCGCVGSLQFVHQECLKKWLKVKITSGADLGAVKTCEMCKQGLLV
660 670 680 690 700 710
730 740 750 760 770 780
pF1KE4 DLGDFNMIEFYQKHQQSQAQNELMNSGLYLVLLLHLYEQRFAELMRLNHNQVERERLSRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::.
XP_005 DLGDFNMIEFYQKHQQSQAQNELMNSGLYLVLLLHLYEQRFAELMRLNHNQVERERIRSW
720 730 740 750 760 770
790 800
pF1KE4 YPQPRTEENENSELGDGNEGSISQSQVV
XP_005 EMEMKAAFLKARSSSKEANCGARRRPLPPALLSTSPSASLPPPLY
780 790 800 810 820
>>NP_001275708 (OMIM: 613337) probable E3 ubiquitin-prot (846 aa)
initn: 4623 init1: 4623 opt: 4623 Z-score: 3478.7 bits: 654.6 E(85289): 5e-187
Smith-Waterman score: 5333; 95.5% identity (95.5% similar) in 840 aa overlap (7-808:7-846)
10 20 30 40 50 60
pF1KE4 MLHDARDRQKFFSDVQYLRDMQHKVDSEYQACLRRQEYRRDPNEKKRDQFWGQETSFERS
::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MLHDARDRQKFFSDVQYLRDMQHKVDSEYQACLRRQEYRRDPNEKKRDQFWGQETSFERS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 RFSSRSSSKQSSSEEDALTEPRSSIKISAFKCDSKLPAIDQTSVKQKHKSTMTVRKAEKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RFSSRSSSKQSSSEEDALTEPRSSIKISAFKCDSKLPAIDQTSVKQKHKSTMTVRKAEKV
70 80 90 100 110 120
130 140
pF1KE4 DPSEPSPA--------------------------------------DQAPMVLLRKRKPN
:::::::: ::::::::::::::
NP_001 DPSEPSPAESEPTWWNKPETDLGGPSGWCSLGKKGPMSRSIPPCEADQAPMVLLRKRKPN
130 140 150 160 170 180
150 160 170 180 190 200
pF1KE4 LRRFTVSPESHSPRASGDRSRQKQQWPAKVPVPRGADQVVQQEGLMCNTKLKRPNQERRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LRRFTVSPESHSPRASGDRSRQKQQWPAKVPVPRGADQVVQQEGLMCNTKLKRPNQERRN
190 200 210 220 230 240
210 220 230 240 250 260
pF1KE4 LVPSSQPMTENAPDRAKKGDPSAPSQSELHPALSQAFQGKNSPQVLSEFSGPPLTPTTVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LVPSSQPMTENAPDRAKKGDPSAPSQSELHPALSQAFQGKNSPQVLSEFSGPPLTPTTVG
250 260 270 280 290 300
270 280 290 300 310 320
pF1KE4 GPRKASFRFRDEDFYSILSLNSRRESDDTEEETQSEECLWVGVRSPCSPSHHKRSRFGGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GPRKASFRFRDEDFYSILSLNSRRESDDTEEETQSEECLWVGVRSPCSPSHHKRSRFGGT
310 320 330 340 350 360
330 340 350 360 370 380
pF1KE4 STPQAKNKNFEENAENCRGHSSRRSEPSHGSLRISNAMEPATERPSAGQRLSQDPGLPDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 STPQAKNKNFEENAENCRGHSSRRSEPSHGSLRISNAMEPATERPSAGQRLSQDPGLPDR
370 380 390 400 410 420
390 400 410 420 430 440
pF1KE4 ESATEKDRGGSENAKKSPLSWDTKSEPRQEVGVNAENVWSDCISVEHRPGTHDSEGYWKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ESATEKDRGGSENAKKSPLSWDTKSEPRQEVGVNAENVWSDCISVEHRPGTHDSEGYWKD
430 440 450 460 470 480
450 460 470 480 490 500
pF1KE4 YLNSSQNSLDYFISGRPISPRSSVNSSYNPPASFMHSALRDDIPVDLSMSSTSVHSSDSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YLNSSQNSLDYFISGRPISPRSSVNSSYNPPASFMHSALRDDIPVDLSMSSTSVHSSDSE
490 500 510 520 530 540
510 520 530 540 550 560
pF1KE4 GNSGFHVCQPLSPIRNRTPFASAENHNYFPVNSAHEFAVREAEDTTLTSQPQGAPLYTDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GNSGFHVCQPLSPIRNRTPFASAENHNYFPVNSAHEFAVREAEDTTLTSQPQGAPLYTDL
550 560 570 580 590 600
570 580 590 600 610 620
pF1KE4 LLNPQGNLSLVDSSSSSPSRMNSEGHLHVSGSLQENTPFTFFAVSHFPNQNDNGSRMAAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLNPQGNLSLVDSSSSSPSRMNSEGHLHVSGSLQENTPFTFFAVSHFPNQNDNGSRMAAS
610 620 630 640 650 660
630 640 650 660 670 680
pF1KE4 GFTDEKETSKIKADPEKLKKLQESLLEEDSEEEGDLCRICQIAGGSPSNPLLEPCGCVGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GFTDEKETSKIKADPEKLKKLQESLLEEDSEEEGDLCRICQIAGGSPSNPLLEPCGCVGS
670 680 690 700 710 720
690 700 710 720 730 740
pF1KE4 LQFVHQECLKKWLKVKITSGADLGAVKTCEMCKQGLLVDLGDFNMIEFYQKHQQSQAQNE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LQFVHQECLKKWLKVKITSGADLGAVKTCEMCKQGLLVDLGDFNMIEFYQKHQQSQAQNE
730 740 750 760 770 780
750 760 770 780 790 800
pF1KE4 LMNSGLYLVLLLHLYEQRFAELMRLNHNQVERERLSRNYPQPRTEENENSELGDGNEGSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LMNSGLYLVLLLHLYEQRFAELMRLNHNQVERERLSRNYPQPRTEENENSELGDGNEGSI
790 800 810 820 830 840
pF1KE4 SQSQVV
::::::
NP_001 SQSQVV
>>XP_005257163 (OMIM: 613337) PREDICTED: probable E3 ubi (752 aa)
initn: 4575 init1: 4409 opt: 4417 Z-score: 3324.9 bits: 626.0 E(85289): 1.8e-178
Smith-Waterman score: 4429; 94.5% identity (94.6% similar) in 704 aa overlap (112-777:1-704)
90 100 110 120
pF1KE4 RSSIKISAFKCDSKLPAIDQTSVKQKHKSTMTVRKAEKVDPSEPSPA-------------
:::::::::::::::::
XP_005 MTVRKAEKVDPSEPSPAESEPTWWNKPETD
10 20 30
130 140 150 160
pF1KE4 -------------------------DQAPMVLLRKRKPNLRRFTVSPESHSPRASGDRSR
:::::::::::::::::::::::::::::::::::
XP_005 LGGPSGWCSLGKKGPMSRSIPPCEADQAPMVLLRKRKPNLRRFTVSPESHSPRASGDRSR
40 50 60 70 80 90
170 180 190 200 210 220
pF1KE4 QKQQWPAKVPVPRGADQVVQQEGLMCNTKLKRPNQERRNLVPSSQPMTENAPDRAKKGDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QKQQWPAKVPVPRGADQVVQQEGLMCNTKLKRPNQERRNLVPSSQPMTENAPDRAKKGDP
100 110 120 130 140 150
230 240 250 260 270 280
pF1KE4 SAPSQSELHPALSQAFQGKNSPQVLSEFSGPPLTPTTVGGPRKASFRFRDEDFYSILSLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SAPSQSELHPALSQAFQGKNSPQVLSEFSGPPLTPTTVGGPRKASFRFRDEDFYSILSLN
160 170 180 190 200 210
290 300 310 320 330 340
pF1KE4 SRRESDDTEEETQSEECLWVGVRSPCSPSHHKRSRFGGTSTPQAKNKNFEENAENCRGHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SRRESDDTEEETQSEECLWVGVRSPCSPSHHKRSRFGGTSTPQAKNKNFEENAENCRGHS
220 230 240 250 260 270
350 360 370 380 390 400
pF1KE4 SRRSEPSHGSLRISNAMEPATERPSAGQRLSQDPGLPDRESATEKDRGGSENAKKSPLSW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SRRSEPSHGSLRISNAMEPATERPSAGQRLSQDPGLPDRESATEKDRGGSENAKKSPLSW
280 290 300 310 320 330
410 420 430 440 450 460
pF1KE4 DTKSEPRQEVGVNAENVWSDCISVEHRPGTHDSEGYWKDYLNSSQNSLDYFISGRPISPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DTKSEPRQEVGVNAENVWSDCISVEHRPGTHDSEGYWKDYLNSSQNSLDYFISGRPISPR
340 350 360 370 380 390
470 480 490 500 510 520
pF1KE4 SSVNSSYNPPASFMHSALRDDIPVDLSMSSTSVHSSDSEGNSGFHVCQPLSPIRNRTPFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SSVNSSYNPPASFMHSALRDDIPVDLSMSSTSVHSSDSEGNSGFHVCQPLSPIRNRTPFA
400 410 420 430 440 450
530 540 550 560 570 580
pF1KE4 SAENHNYFPVNSAHEFAVREAEDTTLTSQPQGAPLYTDLLLNPQGNLSLVDSSSSSPSRM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SAENHNYFPVNSAHEFAVREAEDTTLTSQPQGAPLYTDLLLNPQGNLSLVDSSSSSPSRM
460 470 480 490 500 510
590 600 610 620 630 640
pF1KE4 NSEGHLHVSGSLQENTPFTFFAVSHFPNQNDNGSRMAASGFTDEKETSKIKADPEKLKKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NSEGHLHVSGSLQENTPFTFFAVSHFPNQNDNGSRMAASGFTDEKETSKIKADPEKLKKL
520 530 540 550 560 570
650 660 670 680 690 700
pF1KE4 QESLLEEDSEEEGDLCRICQIAGGSPSNPLLEPCGCVGSLQFVHQECLKKWLKVKITSGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QESLLEEDSEEEGDLCRICQIAGGSPSNPLLEPCGCVGSLQFVHQECLKKWLKVKITSGA
580 590 600 610 620 630
710 720 730 740 750 760
pF1KE4 DLGAVKTCEMCKQGLLVDLGDFNMIEFYQKHQQSQAQNELMNSGLYLVLLLHLYEQRFAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DLGAVKTCEMCKQGLLVDLGDFNMIEFYQKHQQSQAQNELMNSGLYLVLLLHLYEQRFAE
640 650 660 670 680 690
770 780 790 800
pF1KE4 LMRLNHNQVERERLSRNYPQPRTEENENSELGDGNEGSISQSQVV
:::::::::::::.
XP_005 LMRLNHNQVERERIRSWEMEMKAAFLKARSSSKEANCGARRRPLPPALLSTSPSASLPPP
700 710 720 730 740 750
808 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 17:49:35 2016 done: Mon Nov 7 17:49:37 2016
Total Scan time: 11.580 Total Display time: 0.250
Function used was FASTA [36.3.4 Apr, 2011]