Result of FASTA (ccds) for
pFN21AE4212
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE4212, 696 aa
1>>>pF1KE4212 696 - 696 aa - 696 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.6987+/-0.000794; mu= 16.5001+/- 0.048
mean_var=156.3791+/-31.827, 0's: 0 Z-trim(114.3): 44 B-trim: 0 in 0/51
Lambda= 0.102562
statistics sampled from 14855 (14896) to 14855 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.772), E-opt: 0.2 (0.458), width: 16
Scan time: 4.210
The best scores are: opt bits E(32554)
CCDS372.2 RNF19B gene_id:127544|Hs108|chr1 ( 732) 4448 670.1 3.2e-192
CCDS72754.1 RNF19B gene_id:127544|Hs108|chr1 ( 731) 4431 667.6 1.8e-191
CCDS44107.1 RNF19B gene_id:127544|Hs108|chr1 ( 587) 3401 515.1 1.2e-145
CCDS6286.1 RNF19A gene_id:25897|Hs108|chr8 ( 838) 2306 353.2 9e-97
>>CCDS372.2 RNF19B gene_id:127544|Hs108|chr1 (732 aa)
initn: 4448 init1: 4448 opt: 4448 Z-score: 3564.5 bits: 670.1 E(32554): 3.2e-192
Smith-Waterman score: 4730; 95.1% identity (95.1% similar) in 728 aa overlap (5-696:5-732)
10 20 30 40 50 60
pF1KE4 MGSEKDSESPRSTSLHAAAPDPKCRSGGRRRRLTLHSVFSASARGRRARAKPQAEPPPPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS37 MGSEKDSESPRSTSLHAAAPDPKCRSGGRRRRLTLHSVFSASARGRRARAKPQAEPPPPA
10 20 30 40 50 60
70 80
pF1KE4 A------------------------------------EPGFDDEEAAEGGGPGAEEVECP
: :::::::::::::::::::::::
CCDS37 AQPPPAPAPAAAQGPPPEALPAEPAAEAEAEAAAAAAEPGFDDEEAAEGGGPGAEEVECP
70 80 90 100 110 120
90 100 110 120 130 140
pF1KE4 LCLVRLPPERAPRLLSCPHRSCRDCLRHYLRLEISESRVPISCPECSERLNPHDIRLLLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS37 LCLVRLPPERAPRLLSCPHRSCRDCLRHYLRLEISESRVPISCPECSERLNPHDIRLLLA
130 140 150 160 170 180
150 160 170 180 190 200
pF1KE4 DPPLMHKYEEFMLRRYLASDPDCRWCPAPDCGYAVIAYGCASCPKLTCEREGCQTEFCYH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS37 DPPLMHKYEEFMLRRYLASDPDCRWCPAPDCGYAVIAYGCASCPKLTCEREGCQTEFCYH
190 200 210 220 230 240
210 220 230 240 250 260
pF1KE4 CKQIWHPNQTCDMARQQRAQTLRVRTKHTSGLSYGQESGPADDIKPCPRCSAYIIKMNDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS37 CKQIWHPNQTCDMARQQRAQTLRVRTKHTSGLSYGQESGPADDIKPCPRCSAYIIKMNDG
250 260 270 280 290 300
270 280 290 300 310 320
pF1KE4 SCNHMTCAVCGCEFCWLCMKEISDLHYLSPSGCTFWGKKPWSRKKKILWQLGTLIGAPVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS37 SCNHMTCAVCGCEFCWLCMKEISDLHYLSPSGCTFWGKKPWSRKKKILWQLGTLIGAPVG
310 320 330 340 350 360
330 340 350 360 370 380
pF1KE4 ISLIAGIAIPAMVIGIPVYVGRKIHSRYEGRKTSKHKRNLAITGGVTLSVIASPVIAAVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS37 ISLIAGIAIPAMVIGIPVYVGRKIHSRYEGRKTSKHKRNLAITGGVTLSVIASPVIAAVS
370 380 390 400 410 420
390 400 410 420 430 440
pF1KE4 VGIGVPIMLAYVYGVVPISLCRGGGCGVSTANGKGVKIEFDEDDGPITVADAWRALKNPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS37 VGIGVPIMLAYVYGVVPISLCRGGGCGVSTANGKGVKIEFDEDDGPITVADAWRALKNPS
430 440 450 460 470 480
450 460 470 480 490 500
pF1KE4 IGESSIEGLTSVLSTSGSPTDGLSVMQGPYSETASFAALSGGTLSGGILSSGKGKYSRLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS37 IGESSIEGLTSVLSTSGSPTDGLSVMQGPYSETASFAALSGGTLSGGILSSGKGKYSRLE
490 500 510 520 530 540
510 520 530 540 550 560
pF1KE4 VQADVQKEIFPKDTASLGAISDNASTRAMAGSIISSYNPQDRECNNMEIQVDIEAKPSHY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS37 VQADVQKEIFPKDTASLGAISDNASTRAMAGSIISSYNPQDRECNNMEIQVDIEAKPSHY
550 560 570 580 590 600
570 580 590 600 610 620
pF1KE4 QLVSGSSTEDSLHVHAQMAENEEEGSGGGGSEEDPPCRHQSCEQKDCLASKPWDISLAQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS37 QLVSGSSTEDSLHVHAQMAENEEEGSGGGGSEEDPPCRHQSCEQKDCLASKPWDISLAQP
610 620 630 640 650 660
630 640 650 660 670 680
pF1KE4 ESIRSDLESSDAQSDDVPDITSDECGSPRSHTAACPSTPRAQGAPSPSAHMNLSALAEGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS37 ESIRSDLESSDAQSDDVPDITSDECGSPRSHTAACPSTPRAQGAPSPSAHMNLSALAEGQ
670 680 690 700 710 720
690
pF1KE4 TVLKPEGGEARV
::::::::::::
CCDS37 TVLKPEGGEARV
730
>>CCDS72754.1 RNF19B gene_id:127544|Hs108|chr1 (731 aa)
initn: 3505 init1: 3051 opt: 4431 Z-score: 3550.9 bits: 667.6 E(32554): 1.8e-191
Smith-Waterman score: 4719; 94.9% identity (94.9% similar) in 729 aa overlap (4-696:4-731)
10 20 30 40 50 60
pF1KE4 MGSEKDSESPRSTSLHAAAPDPKCRSGGRRRRLTLHSVFSASARGRRARAKPQAEPPPPA
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS72 MGSEKDSESPRSTSLHAAAPDPKCRSGGRRRRLTLHSVFSASARGRRARAKPQAEPPPPA
10 20 30 40 50 60
70 80
pF1KE4 A------------------------------------EPGFDDEEAAEGGGPGAEEVECP
: :::::::::::::::::::::::
CCDS72 AQPPPAPAPAAAQGPPPEALPAEPAAEAEAEAAAAAAEPGFDDEEAAEGGGPGAEEVECP
70 80 90 100 110 120
90 100 110 120 130 140
pF1KE4 LCLVRLPPERAPRLLSCPHRSCRDCLRHYLRLEISESRVPISCPECSERLNPHDIRLLLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS72 LCLVRLPPERAPRLLSCPHRSCRDCLRHYLRLEISESRVPISCPECSERLNPHDIRLLLA
130 140 150 160 170 180
150 160 170 180 190 200
pF1KE4 DPPLMHKYEEFMLRRYLASDPDCRWCPAPDCGYAVIAYGCASCPKLTCEREGCQTEFCYH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS72 DPPLMHKYEEFMLRRYLASDPDCRWCPAPDCGYAVIAYGCASCPKLTCEREGCQTEFCYH
190 200 210 220 230 240
210 220 230 240 250 260
pF1KE4 CKQIWHPNQTCDMARQQRAQTLRVRTKHTSGLSYGQESGPADDIKPCPRCSAYIIKMNDG
:::::::::::::::::::::::::::::::::::::::: :::::::::::::::::::
CCDS72 CKQIWHPNQTCDMARQQRAQTLRVRTKHTSGLSYGQESGP-DDIKPCPRCSAYIIKMNDG
250 260 270 280 290
270 280 290 300 310 320
pF1KE4 SCNHMTCAVCGCEFCWLCMKEISDLHYLSPSGCTFWGKKPWSRKKKILWQLGTLIGAPVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS72 SCNHMTCAVCGCEFCWLCMKEISDLHYLSPSGCTFWGKKPWSRKKKILWQLGTLIGAPVG
300 310 320 330 340 350
330 340 350 360 370 380
pF1KE4 ISLIAGIAIPAMVIGIPVYVGRKIHSRYEGRKTSKHKRNLAITGGVTLSVIASPVIAAVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS72 ISLIAGIAIPAMVIGIPVYVGRKIHSRYEGRKTSKHKRNLAITGGVTLSVIASPVIAAVS
360 370 380 390 400 410
390 400 410 420 430 440
pF1KE4 VGIGVPIMLAYVYGVVPISLCRGGGCGVSTANGKGVKIEFDEDDGPITVADAWRALKNPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS72 VGIGVPIMLAYVYGVVPISLCRGGGCGVSTANGKGVKIEFDEDDGPITVADAWRALKNPS
420 430 440 450 460 470
450 460 470 480 490 500
pF1KE4 IGESSIEGLTSVLSTSGSPTDGLSVMQGPYSETASFAALSGGTLSGGILSSGKGKYSRLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS72 IGESSIEGLTSVLSTSGSPTDGLSVMQGPYSETASFAALSGGTLSGGILSSGKGKYSRLE
480 490 500 510 520 530
510 520 530 540 550 560
pF1KE4 VQADVQKEIFPKDTASLGAISDNASTRAMAGSIISSYNPQDRECNNMEIQVDIEAKPSHY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS72 VQADVQKEIFPKDTASLGAISDNASTRAMAGSIISSYNPQDRECNNMEIQVDIEAKPSHY
540 550 560 570 580 590
570 580 590 600 610 620
pF1KE4 QLVSGSSTEDSLHVHAQMAENEEEGSGGGGSEEDPPCRHQSCEQKDCLASKPWDISLAQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS72 QLVSGSSTEDSLHVHAQMAENEEEGSGGGGSEEDPPCRHQSCEQKDCLASKPWDISLAQP
600 610 620 630 640 650
630 640 650 660 670 680
pF1KE4 ESIRSDLESSDAQSDDVPDITSDECGSPRSHTAACPSTPRAQGAPSPSAHMNLSALAEGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS72 ESIRSDLESSDAQSDDVPDITSDECGSPRSHTAACPSTPRAQGAPSPSAHMNLSALAEGQ
660 670 680 690 700 710
690
pF1KE4 TVLKPEGGEARV
::::::::::::
CCDS72 TVLKPEGGEARV
720 730
>>CCDS44107.1 RNF19B gene_id:127544|Hs108|chr1 (587 aa)
initn: 2475 init1: 2021 opt: 3401 Z-score: 2728.4 bits: 515.1 E(32554): 1.2e-145
Smith-Waterman score: 3689; 93.6% identity (93.6% similar) in 579 aa overlap (4-546:4-581)
10 20 30 40 50 60
pF1KE4 MGSEKDSESPRSTSLHAAAPDPKCRSGGRRRRLTLHSVFSASARGRRARAKPQAEPPPPA
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 MGSEKDSESPRSTSLHAAAPDPKCRSGGRRRRLTLHSVFSASARGRRARAKPQAEPPPPA
10 20 30 40 50 60
70 80
pF1KE4 A------------------------------------EPGFDDEEAAEGGGPGAEEVECP
: :::::::::::::::::::::::
CCDS44 AQPPPAPAPAAAQGPPPEALPAEPAAEAEAEAAAAAAEPGFDDEEAAEGGGPGAEEVECP
70 80 90 100 110 120
90 100 110 120 130 140
pF1KE4 LCLVRLPPERAPRLLSCPHRSCRDCLRHYLRLEISESRVPISCPECSERLNPHDIRLLLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 LCLVRLPPERAPRLLSCPHRSCRDCLRHYLRLEISESRVPISCPECSERLNPHDIRLLLA
130 140 150 160 170 180
150 160 170 180 190 200
pF1KE4 DPPLMHKYEEFMLRRYLASDPDCRWCPAPDCGYAVIAYGCASCPKLTCEREGCQTEFCYH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 DPPLMHKYEEFMLRRYLASDPDCRWCPAPDCGYAVIAYGCASCPKLTCEREGCQTEFCYH
190 200 210 220 230 240
210 220 230 240 250 260
pF1KE4 CKQIWHPNQTCDMARQQRAQTLRVRTKHTSGLSYGQESGPADDIKPCPRCSAYIIKMNDG
:::::::::::::::::::::::::::::::::::::::: :::::::::::::::::::
CCDS44 CKQIWHPNQTCDMARQQRAQTLRVRTKHTSGLSYGQESGP-DDIKPCPRCSAYIIKMNDG
250 260 270 280 290
270 280 290 300 310 320
pF1KE4 SCNHMTCAVCGCEFCWLCMKEISDLHYLSPSGCTFWGKKPWSRKKKILWQLGTLIGAPVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 SCNHMTCAVCGCEFCWLCMKEISDLHYLSPSGCTFWGKKPWSRKKKILWQLGTLIGAPVG
300 310 320 330 340 350
330 340 350 360 370 380
pF1KE4 ISLIAGIAIPAMVIGIPVYVGRKIHSRYEGRKTSKHKRNLAITGGVTLSVIASPVIAAVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 ISLIAGIAIPAMVIGIPVYVGRKIHSRYEGRKTSKHKRNLAITGGVTLSVIASPVIAAVS
360 370 380 390 400 410
390 400 410 420 430 440
pF1KE4 VGIGVPIMLAYVYGVVPISLCRGGGCGVSTANGKGVKIEFDEDDGPITVADAWRALKNPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 VGIGVPIMLAYVYGVVPISLCRGGGCGVSTANGKGVKIEFDEDDGPITVADAWRALKNPS
420 430 440 450 460 470
450 460 470 480 490 500
pF1KE4 IGESSIEGLTSVLSTSGSPTDGLSVMQGPYSETASFAALSGGTLSGGILSSGKGKYSRLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 IGESSIEGLTSVLSTSGSPTDGLSVMQGPYSETASFAALSGGTLSGGILSSGKGKYSRLE
480 490 500 510 520 530
510 520 530 540 550 560
pF1KE4 VQADVQKEIFPKDTASLGAISDNASTRAMAGSIISSYNPQDRECNNMEIQVDIEAKPSHY
::::::::::::::::::::::::::::::::::::::::::
CCDS44 VQADVQKEIFPKDTASLGAISDNASTRAMAGSIISSYNPQDRFSMIHA
540 550 560 570 580
570 580 590 600 610 620
pF1KE4 QLVSGSSTEDSLHVHAQMAENEEEGSGGGGSEEDPPCRHQSCEQKDCLASKPWDISLAQP
>>CCDS6286.1 RNF19A gene_id:25897|Hs108|chr8 (838 aa)
initn: 1630 init1: 1204 opt: 2306 Z-score: 1850.9 bits: 353.2 E(32554): 9e-97
Smith-Waterman score: 2601; 57.5% identity (77.1% similar) in 708 aa overlap (1-676:38-729)
10 20
pF1KE4 MGSEKDSESPRST-SLHAAAPDPKCRSGGR
:::..: .: :. :: :. ... .
CCDS62 FISKYNEGLCVNTDPVSILTSILDMSLHRQMGSDRDLQSSASSVSL------PSVKKAPK
10 20 30 40 50 60
30 40 50 60 70
pF1KE4 RRRLTLHSVFSASARGRRARAKPQAEPPPPAAEPG------------FDDEEAAEGGGPG
.::... :.: . ..: . .. :. . :. . ....: .
CCDS62 KRRISIGSLFRRKKDNKRKSRELNGGVDGIASIESIHSEMCTDKNSIFSTNTSSDNGLTS
70 80 90 100 110 120
80 90 100 110 120 130
pF1KE4 AEE-----VECPLCLVRLPPERAPRLLSCPHRSCRDCLRHYLRLEISESRVPISCPECSE
. .::::::.: .: : ...: :::: ::::.:::.::::::: ::::::.:
CCDS62 ISKQIGDFIECPLCLLRHSKDRFPDIMTCHHRSCVDCLRQYLRIEISESRVNISCPECTE
130 140 150 160 170 180
140 150 160 170 180 190
pF1KE4 RLNPHDIRLLLADPPLMHKYEEFMLRRYLASDPDCRWCPAPDCGYAVIAYGCASCPKLTC
:.:::::::.:.: ::.:::::::::.:..::::::::::::::::::.::::::::::
CCDS62 RFNPHDIRLILSDDVLMEKYEEFMLRRWLVADPDCRWCPAPDCGYAVIAFGCASCPKLTC
190 200 210 220 230 240
200 210 220 230 240 250
pF1KE4 EREGCQTEFCYHCKQIWHPNQTCDMARQQRAQTLRVRTKHTSGLSYGQESGPA-DDIKPC
:::: :::::::::::::::::: :::.:::.::.:: ..:..::.:::: : ::::::
CCDS62 GREGCGTEFCYHCKQIWHPNQTCDAARQERAQSLRLRTIRSSSISYSQESGAAADDIKPC
250 260 270 280 290 300
260 270 280 290 300 310
pF1KE4 PRCSAYIIKMNDGSCNHMTCAVCGCEFCWLCMKEISDLHYLSPSGCTFWGKKPWSRKKKI
:::.::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS62 PRCAAYIIKMNDGSCNHMTCAVCGCEFCWLCMKEISDLHYLSPSGCTFWGKKPWSRKKKI
310 320 330 340 350 360
320 330 340 350 360 370
pF1KE4 LWQLGTLIGAPVGISLIAGIAIPAMVIGIPVYVGRKIHSRYEGRKTSKHKRNLAITGGVT
:::::::.::::::.::::::::::.::::::::::::.::::. .:::::::::.::::
CCDS62 LWQLGTLVGAPVGIALIAGIAIPAMIIGIPVYVGRKIHNRYEGKDVSKHKRNLAIAGGVT
370 380 390 400 410 420
380 390 400 410 420
pF1KE4 LSVIASPVIAAVSVGIGVPIMLAYVYGVVPISLCRGGGCGVSTANGKGVKIEFDEDD---
::::.:::.:::.::::::::::::::::::::::.::::::..:::::.::::...
CCDS62 LSVIVSPVVAAVTVGIGVPIMLAYVYGVVPISLCRSGGCGVSAGNGKGVRIEFDDENDIN
430 440 450 460 470 480
430 440 450 460 470 480
pF1KE4 --GPITVADAW---RALKNPSIGESSIEGLTSVLSTSGSPTDGLSVMQGPYSETASFAAL
: :..:. .: .::::::.:. :::. ::.::: : ..... ::::: ::
CCDS62 VGGTNTAVDTTSVAEARHNPSIGEGSVGGLTGSLSASGSHMDRIGAIRDNLSETASTMAL
490 500 510 520 530 540
490 500 510 520 530
pF1KE4 SGGTLSGGILSSGK-GKYSRLEVQADVQKEIFP----KDTASLGAISDNASTRAMAGSII
.:....:.. .:. . ..::::::::::: . . :.:::..::::::.::::::.
CCDS62 AGASITGSLSGSAMVNCFNRLEVQADVQKERYSLSGESGTVSLGTVSDNASTKAMAGSIL
550 560 570 580 590 600
540 550 560 570 580 590
pF1KE4 SSYNPQDRECNNMEIQVDIEAKPSHYQLVSGSSTEDSLHVHAQMAENEEEGSGGGGSEED
.:: : :.: :.::.:::::.:::... ::::. :. .. .... ::..: :
CCDS62 NSYIPLDKEGNSMEVQVDIESKPSKFRHNSGSSSVDD----GSATRSHAGGSSSGLPEGK
610 620 630 640 650
600 610 620 630 640 650
pF1KE4 PPCRHQSCEQKDCLASKPWDISLAQPESIRSDLESSDAQSDDVPDITSDECGSPRSHTAA
. : : :: . .: :. ::: . . .:.: .: : . .
CCDS62 SSATKWSKEATAGKKSKSGKLRKKGNMKINETREDMDAQLLEQQSTNSSEFEAP-SLSDS
660 670 680 690 700 710
660 670 680 690
pF1KE4 CPSTPRAQGAPSPSAHMNLSALAEGQTVLKPEGGEARV
::. : : :.:..
CCDS62 MPSV-----ADSHSSHFSEFSCSDLESMKTSCSHGSSDYHTRFATVNILPEVENDRLENS
720 730 740 750 760 770
696 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 17:13:28 2016 done: Mon Nov 7 17:13:28 2016
Total Scan time: 4.210 Total Display time: 0.070
Function used was FASTA [36.3.4 Apr, 2011]