FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE4204, 711 aa
  1>>>pF1KE4204 711 - 711 aa - 711 aa
Library: human.CCDS.faa
  18511270 residues in 32554 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 6.3948+/-0.000848; mu= 15.3829+/- 0.051
 mean_var=95.4353+/-18.666, 0's: 0 Z-trim(109.4): 23  B-trim: 5 in 1/48
 Lambda= 0.131286
 statistics sampled from 10823 (10834) to 10823 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.707), E-opt: 0.2 (0.333), width:  16
 Scan time:  2.980

The best scores are:                                      opt bits E(32554)
CCDS32086.1 FBXO34 gene_id:55030|Hs108|chr14       ( 711) 4863 931.6       0
CCDS46116.1 FBXO46 gene_id:23403|Hs108|chr19       ( 603)  762 154.8 3.5e-37


>>CCDS32086.1 FBXO34 gene_id:55030|Hs108|chr14            (711 aa)
 initn: 4863 init1: 4863 opt: 4863  Z-score: 4977.8  bits: 931.6 E(32554):    0
Smith-Waterman score: 4863; 99.7% identity (99.7% similar) in 711 aa overlap (1-711:1-711)

               10        20        30        40        50        60
pF1KE4 MHLKPYWKLQKKEHPPEVSRETQRTPMNHQKAVNDETCKASHITSSVFPSASLGKASSRK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS32 MHLKPYWKLQKKEHPPEVSRETQRTPMNHQKAVNDETCKASHITSSVFPSASLGKASSRK
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE4 PFGILSPNVLCSMSGKSPVESSLNVKTKKNAPSATIHQGEEEGPLDIWAVVKPGNTKEKI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS32 PFGILSPNVLCSMSGKSPVESSLNVKTKKNAPSATIHQGEEEGPLDIWAVVKPGNTKEKI
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE4 AFFASHQCSNRIGSMKIKSSWDIDGRATKRRKKSGDLKKAKVQVERMREVNSRCYQPEPF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS32 AFFASHQCSNRIGSMKIKSSWDIDGRATKRRKKSGDLKKAKVQVERMREVNSRCYQPEPF
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE4 ACGIEHCSVHYVSDSGDGVYAGRPLSVIQMVAFLEQRASALLASCSKNCTNSPAIVRFSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS32 ACGIEHCSVHYVSDSGDGVYAGRPLSVIQMVAFLEQRASALLASCSKNCTNSPAIVRFSG
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE4 QSRGVPAVSESYSAPGACEEPTERGNLEVGEPQSEPVRVLDMVAKLESECLKRQGQREPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS32 QSRGVPAVSESYSAPGACEEPTERGNLEVGEPQSEPVRVLDMVAKLESECLKRQGQREPG
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE4 SLSRNNSFRRNVGRVLLANSTQADEGKTKKGVLEAPDTQVNPVGSVSVDCGPSRADRCSP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS32 SLSRNNSFRRNVGRVLLANSTQADEGKTKKGVLEAPDTQVNPVGSVSVDCGPSRADRCSP
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KE4 KEDQAWDGASQDCPPLPAGVSFHIDSAELEPGSQTAVKNSNRYDVEMTDELVGLPFSSHT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS32 KEDQAWDGASQDCPPLPAGVSFHIDSAELEPGSQTAVKNSNRYDVEMTDELVGLPFSSHT
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KE4 YSQASELPTDAVDCMSRELVSLTSRNPDQRKESLCISITVSKVDKDQPSNLNSCEDPVPG
       ::::::::::::::::::::::::::::::::::::::::::::::::: ::::::::::
CCDS32 YSQASELPTDAVDCMSRELVSLTSRNPDQRKESLCISITVSKVDKDQPSILNSCEDPVPG
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KE4 MLFFLPPGQHLSDYSQLNESTTKESSEASQLEDAAGGDSASEEKSGSAEPFVPPASSVES
       :::::::::::::::::::::::::::::::::::::::::::::::::::: :::::::
CCDS32 MLFFLPPGQHLSDYSQLNESTTKESSEASQLEDAAGGDSASEEKSGSAEPFVLPASSVES
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KE4 TLPVLEASSWKKQVSHDFLETRFKIQQLLEPQQYMAFLPHHIMVKIFRLLPTKSLVALKC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS32 TLPVLEASSWKKQVSHDFLETRFKIQQLLEPQQYMAFLPHHIMVKIFRLLPTKSLVALKC
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KE4 TCCYFKFIIEYYNIRPADSRWVRDPRYREDPCKQCKKKYVKGDVSLCRWHPKPYCQALPY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS32 TCCYFKFIIEYYNIRPADSRWVRDPRYREDPCKQCKKKYVKGDVSLCRWHPKPYCQALPY
              610       620       630       640       650       660

              670       680       690       700       710 
pF1KE4 GPGYWMCCHRSQKGFPGCKLGLHDNHWVPACHSFNRAIHKKAKGTEAEEEY
       :::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS32 GPGYWMCCHRSQKGFPGCKLGLHDNHWVPACHSFNRAIHKKAKGTEAEEEY
              670       680       690       700       710 

>>CCDS46116.1 FBXO46 gene_id:23403|Hs108|chr19            (603 aa)
 initn: 1014 init1: 747 opt: 762  Z-score: 780.9  bits: 154.8 E(32554): 3.5e-37
Smith-Waterman score: 1011; 34.2% identity (54.7% similar) in 658 aa overlap (49-692:28-590)

       20        30        40        50        60        70        
pF1KE4 SRETQRTPMNHQKAVNDETCKASHITSSVFPSASLGKASSRKPFGILSPNVLCSMSGKSP
                                     :::.:  ..  .: :   :.   . : ..:
CCDS46    MDRGSLLPFQLWCPRPFGTYSQNQPRPPSAALKPSACPEPGGGAEPDHGPAHSENTP
                  10        20        30        40        50       

       80        90       100         110       120         130    
pF1KE4 VESSLNVKTKKNAPSATIHQGEEEGP--LDIWAVVKPGNTKEKIAFFASHQCS--NRIGS
          . .: ... ::  .   . .::   :: : :.::::::::.:::..:::.  .: .:
CCDS46 PALATEVPASQPAPLLSAAAAGDEGRVLLDTWYVIKPGNTKEKVAFFVAHQCGGGSRASS
        60        70        80        90       100       110       

          140       150       160       170       180       190    
pF1KE4 MKIKSSWDIDGRATKRRKKSGDLKKAKVQVERMREVNSRCYQPEPFACGIEHCSVHYVSD
       ::.:. :  :.  .:::..  :  ::                :.: .      . .  ..
CCDS46 MKVKGHWGSDSSKAKRRRRCLDPTKAP---------------PDPGGREGPPAAEEGPAS
       120       130       140                      150       160  

          200       210       220       230       240          250 
pF1KE4 SGDGVYAGRPLSVIQMVAFLEQRASALLASCSKNCTNSPAIVRFSGQSRGVPAV---SES
       .:. :     ::: .:::..::::.  : :  .  :  :: : : .  .: ::    :: 
CCDS46 AGEDVDL---LSVAEMVALVEQRAALALQSYPRPTT--PAPVVFVSAEQGGPAKGVGSER
               170       180       190         200       210       

             260       270       280       290       300       310 
pF1KE4 YSAPGACEEPTERGNLEVGEPQSEPVRVLDMVAKLESECLKRQGQREPGSLSRNNSFRRN
        :. : : . .:      .. .: :..       :..:  .: :   ::      .:: .
CCDS46 RSGGGDCSRVAEAVAHFEAQRDSPPTK------GLRKE--ERPG---PGPGEVRIAFRIS
       220       230       240               250          260      

             320       330       340       350        360       370
pF1KE4 VGRVLLANSTQADEGKTKKGVLEAPDTQVNPVGSVSVDCG-PSRADRCSPKEDQAWDGAS
        ::          : .       :::. .   :.    :. :.     .  .:.      
CCDS46 NGR----------EPR-------APDSGLPSGGGGRPGCAYPGSPGPGARAKDKITCDLY
                  270              280       290       300         

                  380       390       400       410       420      
pF1KE4 QDCPP----LPAGVSFHIDSAELEPGSQTAVKNSNRYDVEMTDELVGLPFSSHTYSQASE
       :   :    ::..: : .  :.       : ....   ..  :   . :        :: 
CCDS46 QLISPSRDALPSNVEFLLARAD------EASEGDSPAPARPEDTPPAPPPPPARDCGASG
     310       320       330             340       350       360   

        430       440         450       460       470       480    
pF1KE4 LPTDAVDCMSRELVSLTSRNPDQ--RKESLCISITVSKVDKDQPSNLNSCEDPVPGMLFF
       . .:.:     .   . ...  .  ..:..:....        :      : : ::.:::
CCDS46 FHVDVVVTGVVDECIFFGKDGTKNVKEETVCLTVS--------PE-----EPPPPGQLFF
           370       380       390               400            410

          490       500       510       520       530       540    
pF1KE4 LPPGQHLSDYSQLNESTTKESSEASQLEDAAGGDSASEEKSGSAEPFVPPASSVESTLPV
       :         .. . .   :   :..   : : :.:     :.:.          ..:  
CCDS46 L---------QNRGPDGPPEPPPADSPATAPGPDDAE----GTAD----------TSLCR
                       420       430           440                 

          550       560       570       580       590       600    
pF1KE4 LEASSWKKQVSHDFLETRFKIQQLLEPQQYMAFLPHHIMVKIFRLLPTKSLVALKCTCCY
       :      ..::::::: :::::.::::.::: .::.:..:::: .:::..:.:::::: .
CCDS46 LY-----RHVSHDFLEIRFKIQRLLEPRQYMLLLPEHVLVKIFSFLPTRALAALKCTCHH
            450       460       470       480       490       500  

          610       620       630       640       650       660    
pF1KE4 FKFIIEYYNIRPADSRWVRDPRYREDPCKQCKKKYVKGDVSLCRWHPKPYCQALPYGPGY
       :: ::: ...: .:::: ::: ::.::::::.:.: :::::::::::::: . :::: .:
CCDS46 FKGIIEAFGVRATDSRWSRDPLYRDDPCKQCRKRYEKGDVSLCRWHPKPYHHDLPYGRSY
            510       520       530       540       550       560  

          670       680       690       700       710 
pF1KE4 WMCCHRSQKGFPGCKLGLHDNHWVPACHSFNRAIHKKAKGTEAEEEY
       ::::.:...  :::.::::::.::  :.                   
CCDS46 WMCCRRADRETPGCRLGLHDNNWVLPCNGPGGGRAGREEGR      
            570       580       590       600         




711 residues in 1 query   sequences
18511270 residues in 32554 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sun Nov  6 01:30:20 2016 done: Sun Nov  6 01:30:20 2016
 Total Scan time:  2.980 Total Display time:  0.020

Function used was FASTA [36.3.4 Apr, 2011]