Result of FASTA (omim) for
pFN21AE4195
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE4195, 704 aa
1>>>pF1KE4195 704 - 704 aa - 704 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.6757+/-0.000445; mu= 3.9157+/- 0.028
mean_var=168.6714+/-35.815, 0's: 0 Z-trim(116.6): 97 B-trim: 1548 in 2/52
Lambda= 0.098754
statistics sampled from 27810 (27914) to 27810 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.667), E-opt: 0.2 (0.327), width: 16
Scan time: 11.300
The best scores are: opt bits E(85289)
NP_073737 (OMIM: 613334) E3 ubiquitin-protein liga ( 704) 4579 665.1 2.6e-190
XP_005246830 (OMIM: 613334) PREDICTED: E3 ubiquiti ( 704) 4579 665.1 2.6e-190
NP_001269734 (OMIM: 613334) E3 ubiquitin-protein l ( 704) 4579 665.1 2.6e-190
XP_005246831 (OMIM: 613334) PREDICTED: E3 ubiquiti ( 691) 4351 632.6 1.5e-180
XP_016860207 (OMIM: 613334) PREDICTED: E3 ubiquiti ( 691) 4351 632.6 1.5e-180
NP_001269736 (OMIM: 613334) E3 ubiquitin-protein l ( 666) 4252 618.5 2.6e-176
XP_016860209 (OMIM: 613334) PREDICTED: E3 ubiquiti ( 648) 3479 508.3 3.7e-143
XP_016860208 (OMIM: 613334) PREDICTED: E3 ubiquiti ( 648) 3479 508.3 3.7e-143
NP_001269735 (OMIM: 613334) E3 ubiquitin-protein l ( 635) 3251 475.9 2.2e-133
XP_016860210 (OMIM: 613334) PREDICTED: E3 ubiquiti ( 635) 3251 475.9 2.2e-133
XP_011522739 (OMIM: 613337) PREDICTED: probable E3 ( 807) 583 95.8 7.1e-19
NP_001094345 (OMIM: 613337) probable E3 ubiquitin- ( 808) 583 95.8 7.1e-19
NP_689811 (OMIM: 613337) probable E3 ubiquitin-pro ( 808) 583 95.8 7.1e-19
NP_001275708 (OMIM: 613337) probable E3 ubiquitin- ( 846) 583 95.8 7.4e-19
XP_005257163 (OMIM: 613337) PREDICTED: probable E3 ( 752) 572 94.2 2e-18
XP_005257160 (OMIM: 613337) PREDICTED: probable E3 ( 799) 572 94.2 2.1e-18
NP_001275709 (OMIM: 613337) probable E3 ubiquitin- ( 799) 572 94.2 2.1e-18
XP_005257159 (OMIM: 613337) PREDICTED: probable E3 ( 824) 572 94.2 2.1e-18
XP_011522738 (OMIM: 613337) PREDICTED: probable E3 ( 825) 572 94.2 2.1e-18
XP_005257157 (OMIM: 613337) PREDICTED: probable E3 ( 825) 572 94.2 2.1e-18
XP_005257155 (OMIM: 613337) PREDICTED: probable E3 ( 862) 572 94.2 2.2e-18
XP_011522737 (OMIM: 613337) PREDICTED: probable E3 ( 862) 572 94.2 2.2e-18
XP_005257154 (OMIM: 613337) PREDICTED: probable E3 ( 863) 572 94.2 2.2e-18
XP_005257152 (OMIM: 613337) PREDICTED: probable E3 ( 863) 572 94.2 2.2e-18
XP_005257153 (OMIM: 613337) PREDICTED: probable E3 ( 863) 572 94.2 2.2e-18
NP_055023 (OMIM: 125420,125485,125490,125500,60559 (1301) 290 54.1 3.9e-06
XP_016861969 (OMIM: 161565) PREDICTED: NK-tumor re (1094) 232 45.8 0.001
XP_016861967 (OMIM: 161565) PREDICTED: NK-tumor re (1095) 232 45.8 0.001
XP_016861968 (OMIM: 161565) PREDICTED: NK-tumor re (1095) 232 45.8 0.001
XP_016861966 (OMIM: 161565) PREDICTED: NK-tumor re (1163) 232 45.9 0.0011
XP_016861965 (OMIM: 161565) PREDICTED: NK-tumor re (1163) 232 45.9 0.0011
XP_011532052 (OMIM: 161565) PREDICTED: NK-tumor re (1210) 232 45.9 0.0011
XP_011532049 (OMIM: 161565) PREDICTED: NK-tumor re (1210) 232 45.9 0.0011
XP_016861964 (OMIM: 161565) PREDICTED: NK-tumor re (1210) 232 45.9 0.0011
XP_006713236 (OMIM: 161565) PREDICTED: NK-tumor re (1353) 232 45.9 0.0012
XP_016861963 (OMIM: 161565) PREDICTED: NK-tumor re (1435) 232 45.9 0.0013
XP_006713234 (OMIM: 161565) PREDICTED: NK-tumor re (1436) 232 45.9 0.0013
NP_005376 (OMIM: 161565) NK-tumor recognition prot (1462) 232 45.9 0.0013
XP_005265230 (OMIM: 161565) PREDICTED: NK-tumor re (1463) 232 45.9 0.0013
NP_001010909 (OMIM: 616991) mucin-21 isoform 1 pre ( 566) 208 42.3 0.0063
>>NP_073737 (OMIM: 613334) E3 ubiquitin-protein ligase M (704 aa)
initn: 4579 init1: 4579 opt: 4579 Z-score: 3537.6 bits: 665.1 E(85289): 2.6e-190
Smith-Waterman score: 4579; 100.0% identity (100.0% similar) in 704 aa overlap (1-704:1-704)
10 20 30 40 50 60
pF1KE4 MESKPSRIPRRISVQPSSSLSARMMSGSRGSSLNDTYHSRDSSFRLDSEYQSTSASASAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_073 MESKPSRIPRRISVQPSSSLSARMMSGSRGSSLNDTYHSRDSSFRLDSEYQSTSASASAS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 PFQSAWYSESEITQGARSRSQNQQRDHDSKRPKLSCTNCTTSAGRNVGNGLNTLSDSSWR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_073 PFQSAWYSESEITQGARSRSQNQQRDHDSKRPKLSCTNCTTSAGRNVGNGLNTLSDSSWR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 HSQVPRSSSMVLGSFGTDLMRERRDLERRTDSSISNLMDYSHRSGDFTTSSYVQDRVPSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_073 HSQVPRSSSMVLGSFGTDLMRERRDLERRTDSSISNLMDYSHRSGDFTTSSYVQDRVPSY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 SQGARPKENSMSTLQLNTSSTNHQLPSEHQTILSSRDSRNSLRSNFSSRESESSRSNTQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_073 SQGARPKENSMSTLQLNTSSTNHQLPSEHQTILSSRDSRNSLRSNFSSRESESSRSNTQP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 GFSYSSSRDEAPIISNSERVVSSQRPFQESSDNEGRRTTRRLLSRIASSMSSTFFSRRSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_073 GFSYSSSRDEAPIISNSERVVSSQRPFQESSDNEGRRTTRRLLSRIASSMSSTFFSRRSS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 QDSLNTRSLNSENSYVSPRILTASQSRSNVPSASEVPDNRASEASQGFRFLRRRWGLSSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_073 QDSLNTRSLNSENSYVSPRILTASQSRSNVPSASEVPDNRASEASQGFRFLRRRWGLSSL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 SHNHSSESDSENFNQESEGRNTGPWLSSSLRNRCTPLFSRRRREGRDESSRIPTSDTSSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_073 SHNHSSESDSENFNQESEGRNTGPWLSSSLRNRCTPLFSRRRREGRDESSRIPTSDTSSR
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE4 SHIFRRESNEVVHLEAQNDPLGAAANRPQASAASSSATTGGSTSDSAQGGRNTGISGILP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_073 SHIFRRESNEVVHLEAQNDPLGAAANRPQASAASSSATTGGSTSDSAQGGRNTGISGILP
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE4 GSLFRFAVPPALGSNLTDNVMITVDIIPSGWNSADGKSDKTKSAPSRDPERLQKIKESLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_073 GSLFRFAVPPALGSNLTDNVMITVDIIPSGWNSADGKSDKTKSAPSRDPERLQKIKESLL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE4 LEDSEEEEGDLCRICQMAAASSSNLLIEPCKCTGSLQYVHQDCMKKWLQAKINSGSSLEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_073 LEDSEEEEGDLCRICQMAAASSSNLLIEPCKCTGSLQYVHQDCMKKWLQAKINSGSSLEA
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE4 VTTCELCKEKLELNLEDFDIHELHRAHANEQAEYEFISSGLYLVVLLHLCEQSFSDMMGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_073 VTTCELCKEKLELNLEDFDIHELHRAHANEQAEYEFISSGLYLVVLLHLCEQSFSDMMGN
610 620 630 640 650 660
670 680 690 700
pF1KE4 TNEPSTRVRFINLARTLQAHMEDLETSEDDSEEDGDHNRTFDIA
::::::::::::::::::::::::::::::::::::::::::::
NP_073 TNEPSTRVRFINLARTLQAHMEDLETSEDDSEEDGDHNRTFDIA
670 680 690 700
>>XP_005246830 (OMIM: 613334) PREDICTED: E3 ubiquitin-pr (704 aa)
initn: 4579 init1: 4579 opt: 4579 Z-score: 3537.6 bits: 665.1 E(85289): 2.6e-190
Smith-Waterman score: 4579; 100.0% identity (100.0% similar) in 704 aa overlap (1-704:1-704)
10 20 30 40 50 60
pF1KE4 MESKPSRIPRRISVQPSSSLSARMMSGSRGSSLNDTYHSRDSSFRLDSEYQSTSASASAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MESKPSRIPRRISVQPSSSLSARMMSGSRGSSLNDTYHSRDSSFRLDSEYQSTSASASAS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 PFQSAWYSESEITQGARSRSQNQQRDHDSKRPKLSCTNCTTSAGRNVGNGLNTLSDSSWR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PFQSAWYSESEITQGARSRSQNQQRDHDSKRPKLSCTNCTTSAGRNVGNGLNTLSDSSWR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 HSQVPRSSSMVLGSFGTDLMRERRDLERRTDSSISNLMDYSHRSGDFTTSSYVQDRVPSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HSQVPRSSSMVLGSFGTDLMRERRDLERRTDSSISNLMDYSHRSGDFTTSSYVQDRVPSY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 SQGARPKENSMSTLQLNTSSTNHQLPSEHQTILSSRDSRNSLRSNFSSRESESSRSNTQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SQGARPKENSMSTLQLNTSSTNHQLPSEHQTILSSRDSRNSLRSNFSSRESESSRSNTQP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 GFSYSSSRDEAPIISNSERVVSSQRPFQESSDNEGRRTTRRLLSRIASSMSSTFFSRRSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GFSYSSSRDEAPIISNSERVVSSQRPFQESSDNEGRRTTRRLLSRIASSMSSTFFSRRSS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 QDSLNTRSLNSENSYVSPRILTASQSRSNVPSASEVPDNRASEASQGFRFLRRRWGLSSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QDSLNTRSLNSENSYVSPRILTASQSRSNVPSASEVPDNRASEASQGFRFLRRRWGLSSL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 SHNHSSESDSENFNQESEGRNTGPWLSSSLRNRCTPLFSRRRREGRDESSRIPTSDTSSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SHNHSSESDSENFNQESEGRNTGPWLSSSLRNRCTPLFSRRRREGRDESSRIPTSDTSSR
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE4 SHIFRRESNEVVHLEAQNDPLGAAANRPQASAASSSATTGGSTSDSAQGGRNTGISGILP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SHIFRRESNEVVHLEAQNDPLGAAANRPQASAASSSATTGGSTSDSAQGGRNTGISGILP
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE4 GSLFRFAVPPALGSNLTDNVMITVDIIPSGWNSADGKSDKTKSAPSRDPERLQKIKESLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GSLFRFAVPPALGSNLTDNVMITVDIIPSGWNSADGKSDKTKSAPSRDPERLQKIKESLL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE4 LEDSEEEEGDLCRICQMAAASSSNLLIEPCKCTGSLQYVHQDCMKKWLQAKINSGSSLEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LEDSEEEEGDLCRICQMAAASSSNLLIEPCKCTGSLQYVHQDCMKKWLQAKINSGSSLEA
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE4 VTTCELCKEKLELNLEDFDIHELHRAHANEQAEYEFISSGLYLVVLLHLCEQSFSDMMGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VTTCELCKEKLELNLEDFDIHELHRAHANEQAEYEFISSGLYLVVLLHLCEQSFSDMMGN
610 620 630 640 650 660
670 680 690 700
pF1KE4 TNEPSTRVRFINLARTLQAHMEDLETSEDDSEEDGDHNRTFDIA
::::::::::::::::::::::::::::::::::::::::::::
XP_005 TNEPSTRVRFINLARTLQAHMEDLETSEDDSEEDGDHNRTFDIA
670 680 690 700
>>NP_001269734 (OMIM: 613334) E3 ubiquitin-protein ligas (704 aa)
initn: 4579 init1: 4579 opt: 4579 Z-score: 3537.6 bits: 665.1 E(85289): 2.6e-190
Smith-Waterman score: 4579; 100.0% identity (100.0% similar) in 704 aa overlap (1-704:1-704)
10 20 30 40 50 60
pF1KE4 MESKPSRIPRRISVQPSSSLSARMMSGSRGSSLNDTYHSRDSSFRLDSEYQSTSASASAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MESKPSRIPRRISVQPSSSLSARMMSGSRGSSLNDTYHSRDSSFRLDSEYQSTSASASAS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 PFQSAWYSESEITQGARSRSQNQQRDHDSKRPKLSCTNCTTSAGRNVGNGLNTLSDSSWR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PFQSAWYSESEITQGARSRSQNQQRDHDSKRPKLSCTNCTTSAGRNVGNGLNTLSDSSWR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 HSQVPRSSSMVLGSFGTDLMRERRDLERRTDSSISNLMDYSHRSGDFTTSSYVQDRVPSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HSQVPRSSSMVLGSFGTDLMRERRDLERRTDSSISNLMDYSHRSGDFTTSSYVQDRVPSY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 SQGARPKENSMSTLQLNTSSTNHQLPSEHQTILSSRDSRNSLRSNFSSRESESSRSNTQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SQGARPKENSMSTLQLNTSSTNHQLPSEHQTILSSRDSRNSLRSNFSSRESESSRSNTQP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 GFSYSSSRDEAPIISNSERVVSSQRPFQESSDNEGRRTTRRLLSRIASSMSSTFFSRRSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GFSYSSSRDEAPIISNSERVVSSQRPFQESSDNEGRRTTRRLLSRIASSMSSTFFSRRSS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 QDSLNTRSLNSENSYVSPRILTASQSRSNVPSASEVPDNRASEASQGFRFLRRRWGLSSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QDSLNTRSLNSENSYVSPRILTASQSRSNVPSASEVPDNRASEASQGFRFLRRRWGLSSL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 SHNHSSESDSENFNQESEGRNTGPWLSSSLRNRCTPLFSRRRREGRDESSRIPTSDTSSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SHNHSSESDSENFNQESEGRNTGPWLSSSLRNRCTPLFSRRRREGRDESSRIPTSDTSSR
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE4 SHIFRRESNEVVHLEAQNDPLGAAANRPQASAASSSATTGGSTSDSAQGGRNTGISGILP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SHIFRRESNEVVHLEAQNDPLGAAANRPQASAASSSATTGGSTSDSAQGGRNTGISGILP
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE4 GSLFRFAVPPALGSNLTDNVMITVDIIPSGWNSADGKSDKTKSAPSRDPERLQKIKESLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GSLFRFAVPPALGSNLTDNVMITVDIIPSGWNSADGKSDKTKSAPSRDPERLQKIKESLL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE4 LEDSEEEEGDLCRICQMAAASSSNLLIEPCKCTGSLQYVHQDCMKKWLQAKINSGSSLEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LEDSEEEEGDLCRICQMAAASSSNLLIEPCKCTGSLQYVHQDCMKKWLQAKINSGSSLEA
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE4 VTTCELCKEKLELNLEDFDIHELHRAHANEQAEYEFISSGLYLVVLLHLCEQSFSDMMGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VTTCELCKEKLELNLEDFDIHELHRAHANEQAEYEFISSGLYLVVLLHLCEQSFSDMMGN
610 620 630 640 650 660
670 680 690 700
pF1KE4 TNEPSTRVRFINLARTLQAHMEDLETSEDDSEEDGDHNRTFDIA
::::::::::::::::::::::::::::::::::::::::::::
NP_001 TNEPSTRVRFINLARTLQAHMEDLETSEDDSEEDGDHNRTFDIA
670 680 690 700
>>XP_005246831 (OMIM: 613334) PREDICTED: E3 ubiquitin-pr (691 aa)
initn: 4381 init1: 4351 opt: 4351 Z-score: 3362.2 bits: 632.6 E(85289): 1.5e-180
Smith-Waterman score: 4351; 99.9% identity (100.0% similar) in 670 aa overlap (1-670:1-670)
10 20 30 40 50 60
pF1KE4 MESKPSRIPRRISVQPSSSLSARMMSGSRGSSLNDTYHSRDSSFRLDSEYQSTSASASAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MESKPSRIPRRISVQPSSSLSARMMSGSRGSSLNDTYHSRDSSFRLDSEYQSTSASASAS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 PFQSAWYSESEITQGARSRSQNQQRDHDSKRPKLSCTNCTTSAGRNVGNGLNTLSDSSWR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PFQSAWYSESEITQGARSRSQNQQRDHDSKRPKLSCTNCTTSAGRNVGNGLNTLSDSSWR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 HSQVPRSSSMVLGSFGTDLMRERRDLERRTDSSISNLMDYSHRSGDFTTSSYVQDRVPSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HSQVPRSSSMVLGSFGTDLMRERRDLERRTDSSISNLMDYSHRSGDFTTSSYVQDRVPSY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 SQGARPKENSMSTLQLNTSSTNHQLPSEHQTILSSRDSRNSLRSNFSSRESESSRSNTQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SQGARPKENSMSTLQLNTSSTNHQLPSEHQTILSSRDSRNSLRSNFSSRESESSRSNTQP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 GFSYSSSRDEAPIISNSERVVSSQRPFQESSDNEGRRTTRRLLSRIASSMSSTFFSRRSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GFSYSSSRDEAPIISNSERVVSSQRPFQESSDNEGRRTTRRLLSRIASSMSSTFFSRRSS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 QDSLNTRSLNSENSYVSPRILTASQSRSNVPSASEVPDNRASEASQGFRFLRRRWGLSSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QDSLNTRSLNSENSYVSPRILTASQSRSNVPSASEVPDNRASEASQGFRFLRRRWGLSSL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 SHNHSSESDSENFNQESEGRNTGPWLSSSLRNRCTPLFSRRRREGRDESSRIPTSDTSSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SHNHSSESDSENFNQESEGRNTGPWLSSSLRNRCTPLFSRRRREGRDESSRIPTSDTSSR
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE4 SHIFRRESNEVVHLEAQNDPLGAAANRPQASAASSSATTGGSTSDSAQGGRNTGISGILP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SHIFRRESNEVVHLEAQNDPLGAAANRPQASAASSSATTGGSTSDSAQGGRNTGISGILP
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE4 GSLFRFAVPPALGSNLTDNVMITVDIIPSGWNSADGKSDKTKSAPSRDPERLQKIKESLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GSLFRFAVPPALGSNLTDNVMITVDIIPSGWNSADGKSDKTKSAPSRDPERLQKIKESLL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE4 LEDSEEEEGDLCRICQMAAASSSNLLIEPCKCTGSLQYVHQDCMKKWLQAKINSGSSLEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LEDSEEEEGDLCRICQMAAASSSNLLIEPCKCTGSLQYVHQDCMKKWLQAKINSGSSLEA
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE4 VTTCELCKEKLELNLEDFDIHELHRAHANEQAEYEFISSGLYLVVLLHLCEQSFSDMMGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VTTCELCKEKLELNLEDFDIHELHRAHANEQAEYEFISSGLYLVVLLHLCEQSFSDMMGN
610 620 630 640 650 660
670 680 690 700
pF1KE4 TNEPSTRVRFINLARTLQAHMEDLETSEDDSEEDGDHNRTFDIA
:::::::::.
XP_005 TNEPSTRVRLQRMIPKKTETITGHLILPNFI
670 680 690
>>XP_016860207 (OMIM: 613334) PREDICTED: E3 ubiquitin-pr (691 aa)
initn: 4381 init1: 4351 opt: 4351 Z-score: 3362.2 bits: 632.6 E(85289): 1.5e-180
Smith-Waterman score: 4351; 99.9% identity (100.0% similar) in 670 aa overlap (1-670:1-670)
10 20 30 40 50 60
pF1KE4 MESKPSRIPRRISVQPSSSLSARMMSGSRGSSLNDTYHSRDSSFRLDSEYQSTSASASAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MESKPSRIPRRISVQPSSSLSARMMSGSRGSSLNDTYHSRDSSFRLDSEYQSTSASASAS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 PFQSAWYSESEITQGARSRSQNQQRDHDSKRPKLSCTNCTTSAGRNVGNGLNTLSDSSWR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PFQSAWYSESEITQGARSRSQNQQRDHDSKRPKLSCTNCTTSAGRNVGNGLNTLSDSSWR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 HSQVPRSSSMVLGSFGTDLMRERRDLERRTDSSISNLMDYSHRSGDFTTSSYVQDRVPSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HSQVPRSSSMVLGSFGTDLMRERRDLERRTDSSISNLMDYSHRSGDFTTSSYVQDRVPSY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 SQGARPKENSMSTLQLNTSSTNHQLPSEHQTILSSRDSRNSLRSNFSSRESESSRSNTQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SQGARPKENSMSTLQLNTSSTNHQLPSEHQTILSSRDSRNSLRSNFSSRESESSRSNTQP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 GFSYSSSRDEAPIISNSERVVSSQRPFQESSDNEGRRTTRRLLSRIASSMSSTFFSRRSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GFSYSSSRDEAPIISNSERVVSSQRPFQESSDNEGRRTTRRLLSRIASSMSSTFFSRRSS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 QDSLNTRSLNSENSYVSPRILTASQSRSNVPSASEVPDNRASEASQGFRFLRRRWGLSSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QDSLNTRSLNSENSYVSPRILTASQSRSNVPSASEVPDNRASEASQGFRFLRRRWGLSSL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 SHNHSSESDSENFNQESEGRNTGPWLSSSLRNRCTPLFSRRRREGRDESSRIPTSDTSSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SHNHSSESDSENFNQESEGRNTGPWLSSSLRNRCTPLFSRRRREGRDESSRIPTSDTSSR
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE4 SHIFRRESNEVVHLEAQNDPLGAAANRPQASAASSSATTGGSTSDSAQGGRNTGISGILP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SHIFRRESNEVVHLEAQNDPLGAAANRPQASAASSSATTGGSTSDSAQGGRNTGISGILP
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE4 GSLFRFAVPPALGSNLTDNVMITVDIIPSGWNSADGKSDKTKSAPSRDPERLQKIKESLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSLFRFAVPPALGSNLTDNVMITVDIIPSGWNSADGKSDKTKSAPSRDPERLQKIKESLL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE4 LEDSEEEEGDLCRICQMAAASSSNLLIEPCKCTGSLQYVHQDCMKKWLQAKINSGSSLEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LEDSEEEEGDLCRICQMAAASSSNLLIEPCKCTGSLQYVHQDCMKKWLQAKINSGSSLEA
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE4 VTTCELCKEKLELNLEDFDIHELHRAHANEQAEYEFISSGLYLVVLLHLCEQSFSDMMGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VTTCELCKEKLELNLEDFDIHELHRAHANEQAEYEFISSGLYLVVLLHLCEQSFSDMMGN
610 620 630 640 650 660
670 680 690 700
pF1KE4 TNEPSTRVRFINLARTLQAHMEDLETSEDDSEEDGDHNRTFDIA
:::::::::.
XP_016 TNEPSTRVRLQRMIPKKTETITGHLILPNFI
670 680 690
>>NP_001269736 (OMIM: 613334) E3 ubiquitin-protein ligas (666 aa)
initn: 4251 init1: 4251 opt: 4252 Z-score: 3286.2 bits: 618.5 E(85289): 2.6e-176
Smith-Waterman score: 4252; 99.4% identity (99.4% similar) in 659 aa overlap (46-704:8-666)
20 30 40 50 60 70
pF1KE4 PSSSLSARMMSGSRGSSLNDTYHSRDSSFRLDSEYQSTSASASASPFQSAWYSESEITQG
: : ::::::::::::::::::::::::
NP_001 MIGNYDHLMSLVTSTSASASASPFQSAWYSESEITQG
10 20 30
80 90 100 110 120 130
pF1KE4 ARSRSQNQQRDHDSKRPKLSCTNCTTSAGRNVGNGLNTLSDSSWRHSQVPRSSSMVLGSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ARSRSQNQQRDHDSKRPKLSCTNCTTSAGRNVGNGLNTLSDSSWRHSQVPRSSSMVLGSF
40 50 60 70 80 90
140 150 160 170 180 190
pF1KE4 GTDLMRERRDLERRTDSSISNLMDYSHRSGDFTTSSYVQDRVPSYSQGARPKENSMSTLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GTDLMRERRDLERRTDSSISNLMDYSHRSGDFTTSSYVQDRVPSYSQGARPKENSMSTLQ
100 110 120 130 140 150
200 210 220 230 240 250
pF1KE4 LNTSSTNHQLPSEHQTILSSRDSRNSLRSNFSSRESESSRSNTQPGFSYSSSRDEAPIIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LNTSSTNHQLPSEHQTILSSRDSRNSLRSNFSSRESESSRSNTQPGFSYSSSRDEAPIIS
160 170 180 190 200 210
260 270 280 290 300 310
pF1KE4 NSERVVSSQRPFQESSDNEGRRTTRRLLSRIASSMSSTFFSRRSSQDSLNTRSLNSENSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NSERVVSSQRPFQESSDNEGRRTTRRLLSRIASSMSSTFFSRRSSQDSLNTRSLNSENSY
220 230 240 250 260 270
320 330 340 350 360 370
pF1KE4 VSPRILTASQSRSNVPSASEVPDNRASEASQGFRFLRRRWGLSSLSHNHSSESDSENFNQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VSPRILTASQSRSNVPSASEVPDNRASEASQGFRFLRRRWGLSSLSHNHSSESDSENFNQ
280 290 300 310 320 330
380 390 400 410 420 430
pF1KE4 ESEGRNTGPWLSSSLRNRCTPLFSRRRREGRDESSRIPTSDTSSRSHIFRRESNEVVHLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ESEGRNTGPWLSSSLRNRCTPLFSRRRREGRDESSRIPTSDTSSRSHIFRRESNEVVHLE
340 350 360 370 380 390
440 450 460 470 480 490
pF1KE4 AQNDPLGAAANRPQASAASSSATTGGSTSDSAQGGRNTGISGILPGSLFRFAVPPALGSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AQNDPLGAAANRPQASAASSSATTGGSTSDSAQGGRNTGISGILPGSLFRFAVPPALGSN
400 410 420 430 440 450
500 510 520 530 540 550
pF1KE4 LTDNVMITVDIIPSGWNSADGKSDKTKSAPSRDPERLQKIKESLLLEDSEEEEGDLCRIC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LTDNVMITVDIIPSGWNSADGKSDKTKSAPSRDPERLQKIKESLLLEDSEEEEGDLCRIC
460 470 480 490 500 510
560 570 580 590 600 610
pF1KE4 QMAAASSSNLLIEPCKCTGSLQYVHQDCMKKWLQAKINSGSSLEAVTTCELCKEKLELNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QMAAASSSNLLIEPCKCTGSLQYVHQDCMKKWLQAKINSGSSLEAVTTCELCKEKLELNL
520 530 540 550 560 570
620 630 640 650 660 670
pF1KE4 EDFDIHELHRAHANEQAEYEFISSGLYLVVLLHLCEQSFSDMMGNTNEPSTRVRFINLAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EDFDIHELHRAHANEQAEYEFISSGLYLVVLLHLCEQSFSDMMGNTNEPSTRVRFINLAR
580 590 600 610 620 630
680 690 700
pF1KE4 TLQAHMEDLETSEDDSEEDGDHNRTFDIA
:::::::::::::::::::::::::::::
NP_001 TLQAHMEDLETSEDDSEEDGDHNRTFDIA
640 650 660
>>XP_016860209 (OMIM: 613334) PREDICTED: E3 ubiquitin-pr (648 aa)
initn: 3460 init1: 3460 opt: 3479 Z-score: 2691.2 bits: 508.3 E(85289): 3.7e-143
Smith-Waterman score: 4088; 92.0% identity (92.0% similar) in 704 aa overlap (1-704:1-648)
10 20 30 40 50 60
pF1KE4 MESKPSRIPRRISVQPSSSLSARMMSGSRGSSLNDTYHSRDSSFRLDSEYQSTSASASAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MESKPSRIPRRISVQPSSSLSARMMSGSRGSSLNDTYHSRDSSFRLDSEYQSTSASASAS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 PFQSAWYSESEITQGARSRSQNQQRDHDSKRPKLSCTNCTTSAGRNVGNGLNTLSDSSWR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PFQSAWYSESEITQGARSRSQNQQRDHDSKRPKLSCTNCTTSAGRNVGNGLNTLSD----
70 80 90 100 110
130 140 150 160 170 180
pF1KE4 HSQVPRSSSMVLGSFGTDLMRERRDLERRTDSSISNLMDYSHRSGDFTTSSYVQDRVPSY
::::::::
XP_016 ----------------------------------------------------VQDRVPSY
120
190 200 210 220 230 240
pF1KE4 SQGARPKENSMSTLQLNTSSTNHQLPSEHQTILSSRDSRNSLRSNFSSRESESSRSNTQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SQGARPKENSMSTLQLNTSSTNHQLPSEHQTILSSRDSRNSLRSNFSSRESESSRSNTQP
130 140 150 160 170 180
250 260 270 280 290 300
pF1KE4 GFSYSSSRDEAPIISNSERVVSSQRPFQESSDNEGRRTTRRLLSRIASSMSSTFFSRRSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GFSYSSSRDEAPIISNSERVVSSQRPFQESSDNEGRRTTRRLLSRIASSMSSTFFSRRSS
190 200 210 220 230 240
310 320 330 340 350 360
pF1KE4 QDSLNTRSLNSENSYVSPRILTASQSRSNVPSASEVPDNRASEASQGFRFLRRRWGLSSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QDSLNTRSLNSENSYVSPRILTASQSRSNVPSASEVPDNRASEASQGFRFLRRRWGLSSL
250 260 270 280 290 300
370 380 390 400 410 420
pF1KE4 SHNHSSESDSENFNQESEGRNTGPWLSSSLRNRCTPLFSRRRREGRDESSRIPTSDTSSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SHNHSSESDSENFNQESEGRNTGPWLSSSLRNRCTPLFSRRRREGRDESSRIPTSDTSSR
310 320 330 340 350 360
430 440 450 460 470 480
pF1KE4 SHIFRRESNEVVHLEAQNDPLGAAANRPQASAASSSATTGGSTSDSAQGGRNTGISGILP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SHIFRRESNEVVHLEAQNDPLGAAANRPQASAASSSATTGGSTSDSAQGGRNTGISGILP
370 380 390 400 410 420
490 500 510 520 530 540
pF1KE4 GSLFRFAVPPALGSNLTDNVMITVDIIPSGWNSADGKSDKTKSAPSRDPERLQKIKESLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSLFRFAVPPALGSNLTDNVMITVDIIPSGWNSADGKSDKTKSAPSRDPERLQKIKESLL
430 440 450 460 470 480
550 560 570 580 590 600
pF1KE4 LEDSEEEEGDLCRICQMAAASSSNLLIEPCKCTGSLQYVHQDCMKKWLQAKINSGSSLEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LEDSEEEEGDLCRICQMAAASSSNLLIEPCKCTGSLQYVHQDCMKKWLQAKINSGSSLEA
490 500 510 520 530 540
610 620 630 640 650 660
pF1KE4 VTTCELCKEKLELNLEDFDIHELHRAHANEQAEYEFISSGLYLVVLLHLCEQSFSDMMGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VTTCELCKEKLELNLEDFDIHELHRAHANEQAEYEFISSGLYLVVLLHLCEQSFSDMMGN
550 560 570 580 590 600
670 680 690 700
pF1KE4 TNEPSTRVRFINLARTLQAHMEDLETSEDDSEEDGDHNRTFDIA
::::::::::::::::::::::::::::::::::::::::::::
XP_016 TNEPSTRVRFINLARTLQAHMEDLETSEDDSEEDGDHNRTFDIA
610 620 630 640
>>XP_016860208 (OMIM: 613334) PREDICTED: E3 ubiquitin-pr (648 aa)
initn: 3460 init1: 3460 opt: 3479 Z-score: 2691.2 bits: 508.3 E(85289): 3.7e-143
Smith-Waterman score: 4088; 92.0% identity (92.0% similar) in 704 aa overlap (1-704:1-648)
10 20 30 40 50 60
pF1KE4 MESKPSRIPRRISVQPSSSLSARMMSGSRGSSLNDTYHSRDSSFRLDSEYQSTSASASAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MESKPSRIPRRISVQPSSSLSARMMSGSRGSSLNDTYHSRDSSFRLDSEYQSTSASASAS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 PFQSAWYSESEITQGARSRSQNQQRDHDSKRPKLSCTNCTTSAGRNVGNGLNTLSDSSWR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PFQSAWYSESEITQGARSRSQNQQRDHDSKRPKLSCTNCTTSAGRNVGNGLNTLSD----
70 80 90 100 110
130 140 150 160 170 180
pF1KE4 HSQVPRSSSMVLGSFGTDLMRERRDLERRTDSSISNLMDYSHRSGDFTTSSYVQDRVPSY
::::::::
XP_016 ----------------------------------------------------VQDRVPSY
120
190 200 210 220 230 240
pF1KE4 SQGARPKENSMSTLQLNTSSTNHQLPSEHQTILSSRDSRNSLRSNFSSRESESSRSNTQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SQGARPKENSMSTLQLNTSSTNHQLPSEHQTILSSRDSRNSLRSNFSSRESESSRSNTQP
130 140 150 160 170 180
250 260 270 280 290 300
pF1KE4 GFSYSSSRDEAPIISNSERVVSSQRPFQESSDNEGRRTTRRLLSRIASSMSSTFFSRRSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GFSYSSSRDEAPIISNSERVVSSQRPFQESSDNEGRRTTRRLLSRIASSMSSTFFSRRSS
190 200 210 220 230 240
310 320 330 340 350 360
pF1KE4 QDSLNTRSLNSENSYVSPRILTASQSRSNVPSASEVPDNRASEASQGFRFLRRRWGLSSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QDSLNTRSLNSENSYVSPRILTASQSRSNVPSASEVPDNRASEASQGFRFLRRRWGLSSL
250 260 270 280 290 300
370 380 390 400 410 420
pF1KE4 SHNHSSESDSENFNQESEGRNTGPWLSSSLRNRCTPLFSRRRREGRDESSRIPTSDTSSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SHNHSSESDSENFNQESEGRNTGPWLSSSLRNRCTPLFSRRRREGRDESSRIPTSDTSSR
310 320 330 340 350 360
430 440 450 460 470 480
pF1KE4 SHIFRRESNEVVHLEAQNDPLGAAANRPQASAASSSATTGGSTSDSAQGGRNTGISGILP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SHIFRRESNEVVHLEAQNDPLGAAANRPQASAASSSATTGGSTSDSAQGGRNTGISGILP
370 380 390 400 410 420
490 500 510 520 530 540
pF1KE4 GSLFRFAVPPALGSNLTDNVMITVDIIPSGWNSADGKSDKTKSAPSRDPERLQKIKESLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSLFRFAVPPALGSNLTDNVMITVDIIPSGWNSADGKSDKTKSAPSRDPERLQKIKESLL
430 440 450 460 470 480
550 560 570 580 590 600
pF1KE4 LEDSEEEEGDLCRICQMAAASSSNLLIEPCKCTGSLQYVHQDCMKKWLQAKINSGSSLEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LEDSEEEEGDLCRICQMAAASSSNLLIEPCKCTGSLQYVHQDCMKKWLQAKINSGSSLEA
490 500 510 520 530 540
610 620 630 640 650 660
pF1KE4 VTTCELCKEKLELNLEDFDIHELHRAHANEQAEYEFISSGLYLVVLLHLCEQSFSDMMGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VTTCELCKEKLELNLEDFDIHELHRAHANEQAEYEFISSGLYLVVLLHLCEQSFSDMMGN
550 560 570 580 590 600
670 680 690 700
pF1KE4 TNEPSTRVRFINLARTLQAHMEDLETSEDDSEEDGDHNRTFDIA
::::::::::::::::::::::::::::::::::::::::::::
XP_016 TNEPSTRVRFINLARTLQAHMEDLETSEDDSEEDGDHNRTFDIA
610 620 630 640
>>NP_001269735 (OMIM: 613334) E3 ubiquitin-protein ligas (635 aa)
initn: 3968 init1: 3227 opt: 3251 Z-score: 2515.8 bits: 475.9 E(85289): 2.2e-133
Smith-Waterman score: 3860; 91.5% identity (91.6% similar) in 670 aa overlap (1-670:1-614)
10 20 30 40 50 60
pF1KE4 MESKPSRIPRRISVQPSSSLSARMMSGSRGSSLNDTYHSRDSSFRLDSEYQSTSASASAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MESKPSRIPRRISVQPSSSLSARMMSGSRGSSLNDTYHSRDSSFRLDSEYQSTSASASAS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 PFQSAWYSESEITQGARSRSQNQQRDHDSKRPKLSCTNCTTSAGRNVGNGLNTLSDSSWR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PFQSAWYSESEITQGARSRSQNQQRDHDSKRPKLSCTNCTTSAGRNVGNGLNTLSD----
70 80 90 100 110
130 140 150 160 170 180
pF1KE4 HSQVPRSSSMVLGSFGTDLMRERRDLERRTDSSISNLMDYSHRSGDFTTSSYVQDRVPSY
::::::::
NP_001 ----------------------------------------------------VQDRVPSY
120
190 200 210 220 230 240
pF1KE4 SQGARPKENSMSTLQLNTSSTNHQLPSEHQTILSSRDSRNSLRSNFSSRESESSRSNTQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SQGARPKENSMSTLQLNTSSTNHQLPSEHQTILSSRDSRNSLRSNFSSRESESSRSNTQP
130 140 150 160 170 180
250 260 270 280 290 300
pF1KE4 GFSYSSSRDEAPIISNSERVVSSQRPFQESSDNEGRRTTRRLLSRIASSMSSTFFSRRSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GFSYSSSRDEAPIISNSERVVSSQRPFQESSDNEGRRTTRRLLSRIASSMSSTFFSRRSS
190 200 210 220 230 240
310 320 330 340 350 360
pF1KE4 QDSLNTRSLNSENSYVSPRILTASQSRSNVPSASEVPDNRASEASQGFRFLRRRWGLSSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QDSLNTRSLNSENSYVSPRILTASQSRSNVPSASEVPDNRASEASQGFRFLRRRWGLSSL
250 260 270 280 290 300
370 380 390 400 410 420
pF1KE4 SHNHSSESDSENFNQESEGRNTGPWLSSSLRNRCTPLFSRRRREGRDESSRIPTSDTSSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SHNHSSESDSENFNQESEGRNTGPWLSSSLRNRCTPLFSRRRREGRDESSRIPTSDTSSR
310 320 330 340 350 360
430 440 450 460 470 480
pF1KE4 SHIFRRESNEVVHLEAQNDPLGAAANRPQASAASSSATTGGSTSDSAQGGRNTGISGILP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SHIFRRESNEVVHLEAQNDPLGAAANRPQASAASSSATTGGSTSDSAQGGRNTGISGILP
370 380 390 400 410 420
490 500 510 520 530 540
pF1KE4 GSLFRFAVPPALGSNLTDNVMITVDIIPSGWNSADGKSDKTKSAPSRDPERLQKIKESLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GSLFRFAVPPALGSNLTDNVMITVDIIPSGWNSADGKSDKTKSAPSRDPERLQKIKESLL
430 440 450 460 470 480
550 560 570 580 590 600
pF1KE4 LEDSEEEEGDLCRICQMAAASSSNLLIEPCKCTGSLQYVHQDCMKKWLQAKINSGSSLEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LEDSEEEEGDLCRICQMAAASSSNLLIEPCKCTGSLQYVHQDCMKKWLQAKINSGSSLEA
490 500 510 520 530 540
610 620 630 640 650 660
pF1KE4 VTTCELCKEKLELNLEDFDIHELHRAHANEQAEYEFISSGLYLVVLLHLCEQSFSDMMGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VTTCELCKEKLELNLEDFDIHELHRAHANEQAEYEFISSGLYLVVLLHLCEQSFSDMMGN
550 560 570 580 590 600
670 680 690 700
pF1KE4 TNEPSTRVRFINLARTLQAHMEDLETSEDDSEEDGDHNRTFDIA
:::::::::.
NP_001 TNEPSTRVRLQRMIPKKTETITGHLILPNFI
610 620 630
>>XP_016860210 (OMIM: 613334) PREDICTED: E3 ubiquitin-pr (635 aa)
initn: 3968 init1: 3227 opt: 3251 Z-score: 2515.8 bits: 475.9 E(85289): 2.2e-133
Smith-Waterman score: 3860; 91.5% identity (91.6% similar) in 670 aa overlap (1-670:1-614)
10 20 30 40 50 60
pF1KE4 MESKPSRIPRRISVQPSSSLSARMMSGSRGSSLNDTYHSRDSSFRLDSEYQSTSASASAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MESKPSRIPRRISVQPSSSLSARMMSGSRGSSLNDTYHSRDSSFRLDSEYQSTSASASAS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 PFQSAWYSESEITQGARSRSQNQQRDHDSKRPKLSCTNCTTSAGRNVGNGLNTLSDSSWR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PFQSAWYSESEITQGARSRSQNQQRDHDSKRPKLSCTNCTTSAGRNVGNGLNTLSD----
70 80 90 100 110
130 140 150 160 170 180
pF1KE4 HSQVPRSSSMVLGSFGTDLMRERRDLERRTDSSISNLMDYSHRSGDFTTSSYVQDRVPSY
::::::::
XP_016 ----------------------------------------------------VQDRVPSY
120
190 200 210 220 230 240
pF1KE4 SQGARPKENSMSTLQLNTSSTNHQLPSEHQTILSSRDSRNSLRSNFSSRESESSRSNTQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SQGARPKENSMSTLQLNTSSTNHQLPSEHQTILSSRDSRNSLRSNFSSRESESSRSNTQP
130 140 150 160 170 180
250 260 270 280 290 300
pF1KE4 GFSYSSSRDEAPIISNSERVVSSQRPFQESSDNEGRRTTRRLLSRIASSMSSTFFSRRSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GFSYSSSRDEAPIISNSERVVSSQRPFQESSDNEGRRTTRRLLSRIASSMSSTFFSRRSS
190 200 210 220 230 240
310 320 330 340 350 360
pF1KE4 QDSLNTRSLNSENSYVSPRILTASQSRSNVPSASEVPDNRASEASQGFRFLRRRWGLSSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QDSLNTRSLNSENSYVSPRILTASQSRSNVPSASEVPDNRASEASQGFRFLRRRWGLSSL
250 260 270 280 290 300
370 380 390 400 410 420
pF1KE4 SHNHSSESDSENFNQESEGRNTGPWLSSSLRNRCTPLFSRRRREGRDESSRIPTSDTSSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SHNHSSESDSENFNQESEGRNTGPWLSSSLRNRCTPLFSRRRREGRDESSRIPTSDTSSR
310 320 330 340 350 360
430 440 450 460 470 480
pF1KE4 SHIFRRESNEVVHLEAQNDPLGAAANRPQASAASSSATTGGSTSDSAQGGRNTGISGILP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SHIFRRESNEVVHLEAQNDPLGAAANRPQASAASSSATTGGSTSDSAQGGRNTGISGILP
370 380 390 400 410 420
490 500 510 520 530 540
pF1KE4 GSLFRFAVPPALGSNLTDNVMITVDIIPSGWNSADGKSDKTKSAPSRDPERLQKIKESLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSLFRFAVPPALGSNLTDNVMITVDIIPSGWNSADGKSDKTKSAPSRDPERLQKIKESLL
430 440 450 460 470 480
550 560 570 580 590 600
pF1KE4 LEDSEEEEGDLCRICQMAAASSSNLLIEPCKCTGSLQYVHQDCMKKWLQAKINSGSSLEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LEDSEEEEGDLCRICQMAAASSSNLLIEPCKCTGSLQYVHQDCMKKWLQAKINSGSSLEA
490 500 510 520 530 540
610 620 630 640 650 660
pF1KE4 VTTCELCKEKLELNLEDFDIHELHRAHANEQAEYEFISSGLYLVVLLHLCEQSFSDMMGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VTTCELCKEKLELNLEDFDIHELHRAHANEQAEYEFISSGLYLVVLLHLCEQSFSDMMGN
550 560 570 580 590 600
670 680 690 700
pF1KE4 TNEPSTRVRFINLARTLQAHMEDLETSEDDSEEDGDHNRTFDIA
:::::::::.
XP_016 TNEPSTRVRLQRMIPKKTETITGHLILPNFI
610 620 630
704 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 09:46:47 2016 done: Sun Nov 6 09:46:48 2016
Total Scan time: 11.300 Total Display time: 0.160
Function used was FASTA [36.3.4 Apr, 2011]