Result of FASTA (omim) for
pFN21AE4175
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE4175, 635 aa
1>>>pF1KE4175 635 - 635 aa - 635 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.4242+/-0.000366; mu= 14.7788+/- 0.023
mean_var=128.2605+/-24.556, 0's: 0 Z-trim(117.6): 211 B-trim: 245 in 1/50
Lambda= 0.113247
statistics sampled from 29483 (29745) to 29483 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.705), E-opt: 0.2 (0.349), width: 16
Scan time: 12.290
The best scores are: opt bits E(85289)
NP_004969 (OMIM: 176265) potassium voltage-gated c ( 635) 4316 716.9 5.2e-206
XP_011539703 (OMIM: 176265) PREDICTED: potassium v ( 609) 4116 684.2 3.5e-196
NP_001034663 (OMIM: 176265) potassium voltage-gate ( 626) 4110 683.3 7e-196
XP_006710690 (OMIM: 176265) PREDICTED: potassium v ( 624) 4109 683.1 7.8e-196
XP_006710688 (OMIM: 176265) PREDICTED: potassium v ( 618) 4108 682.9 8.7e-196
NP_001106212 (OMIM: 176258,616187) potassium volta ( 585) 2648 444.4 5.3e-124
NP_004967 (OMIM: 176258,616187) potassium voltage- ( 511) 2503 420.6 6.5e-117
XP_011518382 (OMIM: 176258,616187) PREDICTED: pota ( 535) 2499 420.0 1.1e-116
NP_001247428 (OMIM: 176256) potassium voltage-gate ( 583) 2359 397.2 8.7e-110
NP_715624 (OMIM: 176256) potassium voltage-gated c ( 558) 2346 395.0 3.7e-109
XP_006719445 (OMIM: 176256) PREDICTED: potassium v ( 613) 2340 394.1 7.8e-109
NP_631874 (OMIM: 176256) potassium voltage-gated c ( 613) 2340 394.1 7.8e-109
NP_001247426 (OMIM: 176256) potassium voltage-gate ( 618) 2340 394.1 7.8e-109
NP_001247427 (OMIM: 176256) potassium voltage-gate ( 629) 2340 394.1 7.9e-109
NP_631875 (OMIM: 176256) potassium voltage-gated c ( 638) 2340 394.1 8e-109
XP_005268912 (OMIM: 176256) PREDICTED: potassium v ( 574) 2337 393.6 1e-108
XP_006719447 (OMIM: 176256) PREDICTED: potassium v ( 612) 2337 393.6 1.1e-108
XP_006719446 (OMIM: 176256) PREDICTED: potassium v ( 612) 2337 393.6 1.1e-108
XP_006719448 (OMIM: 176256) PREDICTED: potassium v ( 612) 2337 393.6 1.1e-108
XP_016874771 (OMIM: 176256) PREDICTED: potassium v ( 612) 2337 393.6 1.1e-108
XP_011525230 (OMIM: 176264,605259) PREDICTED: pota ( 728) 1732 294.8 7e-79
XP_006723266 (OMIM: 176264,605259) PREDICTED: pota ( 757) 1732 294.8 7.2e-79
NP_004968 (OMIM: 176264,605259) potassium voltage- ( 757) 1732 294.8 7.2e-79
XP_011525228 (OMIM: 176264,605259) PREDICTED: pota ( 757) 1732 294.8 7.2e-79
XP_011525227 (OMIM: 176264,605259) PREDICTED: pota ( 768) 1732 294.8 7.3e-79
XP_011539706 (OMIM: 176265) PREDICTED: potassium v ( 319) 1625 277.0 7.1e-74
XP_011539705 (OMIM: 176265) PREDICTED: potassium v ( 403) 1625 277.1 8.4e-74
XP_011539704 (OMIM: 176265) PREDICTED: potassium v ( 403) 1625 277.1 8.4e-74
XP_006719453 (OMIM: 176256) PREDICTED: potassium v ( 255) 741 132.5 1.8e-30
NP_000208 (OMIM: 160120,176260) potassium voltage- ( 495) 650 117.9 8.7e-26
NP_002224 (OMIM: 176266) potassium voltage-gated c ( 653) 642 116.7 2.6e-25
NP_005540 (OMIM: 602420) potassium voltage-gated c ( 511) 640 116.3 2.8e-25
XP_011539701 (OMIM: 176262,616366) PREDICTED: pota ( 499) 620 113.0 2.6e-24
XP_011539702 (OMIM: 176262,616366) PREDICTED: pota ( 499) 620 113.0 2.6e-24
XP_011539699 (OMIM: 176262,616366) PREDICTED: pota ( 499) 620 113.0 2.6e-24
NP_004965 (OMIM: 176262,616366) potassium voltage- ( 499) 620 113.0 2.6e-24
XP_011539700 (OMIM: 176262,616366) PREDICTED: pota ( 499) 620 113.0 2.6e-24
XP_011539698 (OMIM: 176262,616366) PREDICTED: pota ( 499) 620 113.0 2.6e-24
XP_016856702 (OMIM: 176262,616366) PREDICTED: pota ( 499) 620 113.0 2.6e-24
NP_114092 (OMIM: 176268) potassium voltage-gated c ( 456) 611 111.5 6.8e-24
NP_002223 (OMIM: 176263) potassium voltage-gated c ( 575) 606 110.8 1.4e-23
NP_579875 (OMIM: 606767) potassium voltage-gated c ( 436) 583 106.9 1.6e-22
XP_011527101 (OMIM: 600397,616056) PREDICTED: pota ( 858) 537 99.6 4.7e-20
XP_006723847 (OMIM: 600397,616056) PREDICTED: pota ( 858) 537 99.6 4.7e-20
NP_004966 (OMIM: 600397,616056) potassium voltage- ( 858) 537 99.6 4.7e-20
NP_004761 (OMIM: 607738) potassium voltage-gated c ( 911) 530 98.5 1.1e-19
NP_036415 (OMIM: 605696) potassium voltage-gated c ( 466) 506 94.3 1e-18
XP_016881194 (OMIM: 605696) PREDICTED: potassium v ( 466) 506 94.3 1e-18
XP_011524222 (OMIM: 605696) PREDICTED: potassium v ( 466) 506 94.3 1e-18
XP_011524220 (OMIM: 605696) PREDICTED: potassium v ( 466) 506 94.3 1e-18
>>NP_004969 (OMIM: 176265) potassium voltage-gated chann (635 aa)
initn: 4316 init1: 4316 opt: 4316 Z-score: 3819.5 bits: 716.9 E(85289): 5.2e-206
Smith-Waterman score: 4316; 99.8% identity (99.8% similar) in 635 aa overlap (1-635:1-635)
10 20 30 40 50 60
pF1KE4 MISSVCVSSYRGRKSGNKPPSKTCLKEEMAKGEASEKIIINVGGTRHETYRSTLRTLPGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MISSVCVSSYRGRKSGNKPPSKTCLKEEMAKGEASEKIIINVGGTRHETYRSTLRTLPGT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 RLAWLADPDGGGRPETDGGGVGSSGSSGGGGCEFFFDRHPGVFAYVLNYYRTGKLHCPAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 RLAWLADPDGGGRPETDGGGVGSSGSSGGGGCEFFFDRHPGVFAYVLNYYRTGKLHCPAD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 VCGPLFEEELTFWGIDETDVEPCCWMTYRQHRDAEEALDIFESPDGGGSGAGPSDEAGDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 VCGPLFEEELTFWGIDETDVEPCCWMTYRQHRDAEEALDIFESPDGGGSGAGPSDEAGDD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 ERELALQRLGPHEGGAGHGAGSGGCRGWQPRMWALFEDPYSSRAARVVAFASLFFILVSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 ERELALQRLGPHEGGAGHGAGSGGCRGWQPRMWALFEDPYSSRAARVVAFASLFFILVSI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 TTFCLETHEAFNIDRNVTEILRVGNITSVHFRREVETEPILTYIEGVCVLWFTLEFLVRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 TTFCLETHEAFNIDRNVTEILRVGNITSVHFRREVETEPILTYIEGVCVLWFTLEFLVRI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 VCCPDTLDFVKNLLNIIDFVAILPFYLEVGLSGLSSKAARDVLGFLRVVRFVRILRIFKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 VCCPDTLDFVKNLLNIIDFVAILPFYLEVGLSGLSSKAARDVLGFLRVVRFVRILRIFKL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 TRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGARPSDPRGNDHTDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 TRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGARPSDPRGNDHTDF
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE4 KNIPIGFWWAVVTMTTLGYGDMYPKTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 KNIPIGFWWAVVTMTTLGYGDMYPKTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE4 LAMAKQKLPKKRKKHVPRPAQLESPMYCKSEETSPRDSTYSDTSPPAREEGMIERKRADS
::::::::::::::::::::::::::::::::::::::: ::::::::::::::::::::
NP_004 LAMAKQKLPKKRKKHVPRPAQLESPMYCKSEETSPRDSTCSDTSPPAREEGMIERKRADS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE4 KQNGDANAVLSDEEGAGLTQPLASSPTPEERRALRRSTTRDRNKKAAACFLLSTGDYACA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 KQNGDANAVLSDEEGAGLTQPLASSPTPEERRALRRSTTRDRNKKAAACFLLSTGDYACA
550 560 570 580 590 600
610 620 630
pF1KE4 DGSVRKGTFVLRDLPLQHSPEAACPPTAGTLFLPH
:::::::::::::::::::::::::::::::::::
NP_004 DGSVRKGTFVLRDLPLQHSPEAACPPTAGTLFLPH
610 620 630
>>XP_011539703 (OMIM: 176265) PREDICTED: potassium volta (609 aa)
initn: 4116 init1: 4116 opt: 4116 Z-score: 3643.2 bits: 684.2 E(85289): 3.5e-196
Smith-Waterman score: 4116; 99.8% identity (99.8% similar) in 607 aa overlap (1-607:1-607)
10 20 30 40 50 60
pF1KE4 MISSVCVSSYRGRKSGNKPPSKTCLKEEMAKGEASEKIIINVGGTRHETYRSTLRTLPGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MISSVCVSSYRGRKSGNKPPSKTCLKEEMAKGEASEKIIINVGGTRHETYRSTLRTLPGT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 RLAWLADPDGGGRPETDGGGVGSSGSSGGGGCEFFFDRHPGVFAYVLNYYRTGKLHCPAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RLAWLADPDGGGRPETDGGGVGSSGSSGGGGCEFFFDRHPGVFAYVLNYYRTGKLHCPAD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 VCGPLFEEELTFWGIDETDVEPCCWMTYRQHRDAEEALDIFESPDGGGSGAGPSDEAGDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VCGPLFEEELTFWGIDETDVEPCCWMTYRQHRDAEEALDIFESPDGGGSGAGPSDEAGDD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 ERELALQRLGPHEGGAGHGAGSGGCRGWQPRMWALFEDPYSSRAARVVAFASLFFILVSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ERELALQRLGPHEGGAGHGAGSGGCRGWQPRMWALFEDPYSSRAARVVAFASLFFILVSI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 TTFCLETHEAFNIDRNVTEILRVGNITSVHFRREVETEPILTYIEGVCVLWFTLEFLVRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TTFCLETHEAFNIDRNVTEILRVGNITSVHFRREVETEPILTYIEGVCVLWFTLEFLVRI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 VCCPDTLDFVKNLLNIIDFVAILPFYLEVGLSGLSSKAARDVLGFLRVVRFVRILRIFKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VCCPDTLDFVKNLLNIIDFVAILPFYLEVGLSGLSSKAARDVLGFLRVVRFVRILRIFKL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 TRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGARPSDPRGNDHTDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGARPSDPRGNDHTDF
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE4 KNIPIGFWWAVVTMTTLGYGDMYPKTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KNIPIGFWWAVVTMTTLGYGDMYPKTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE4 LAMAKQKLPKKRKKHVPRPAQLESPMYCKSEETSPRDSTYSDTSPPAREEGMIERKRADS
::::::::::::::::::::::::::::::::::::::: ::::::::::::::::::::
XP_011 LAMAKQKLPKKRKKHVPRPAQLESPMYCKSEETSPRDSTCSDTSPPAREEGMIERKRADS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE4 KQNGDANAVLSDEEGAGLTQPLASSPTPEERRALRRSTTRDRNKKAAACFLLSTGDYACA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KQNGDANAVLSDEEGAGLTQPLASSPTPEERRALRRSTTRDRNKKAAACFLLSTGDYACA
550 560 570 580 590 600
610 620 630
pF1KE4 DGSVRKGTFVLRDLPLQHSPEAACPPTAGTLFLPH
:::::::
XP_011 DGSVRKGKI
>>NP_001034663 (OMIM: 176265) potassium voltage-gated ch (626 aa)
initn: 4204 init1: 4110 opt: 4110 Z-score: 3637.7 bits: 683.3 E(85289): 7e-196
Smith-Waterman score: 4110; 99.7% identity (99.7% similar) in 608 aa overlap (1-608:1-608)
10 20 30 40 50 60
pF1KE4 MISSVCVSSYRGRKSGNKPPSKTCLKEEMAKGEASEKIIINVGGTRHETYRSTLRTLPGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MISSVCVSSYRGRKSGNKPPSKTCLKEEMAKGEASEKIIINVGGTRHETYRSTLRTLPGT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 RLAWLADPDGGGRPETDGGGVGSSGSSGGGGCEFFFDRHPGVFAYVLNYYRTGKLHCPAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RLAWLADPDGGGRPETDGGGVGSSGSSGGGGCEFFFDRHPGVFAYVLNYYRTGKLHCPAD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 VCGPLFEEELTFWGIDETDVEPCCWMTYRQHRDAEEALDIFESPDGGGSGAGPSDEAGDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VCGPLFEEELTFWGIDETDVEPCCWMTYRQHRDAEEALDIFESPDGGGSGAGPSDEAGDD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 ERELALQRLGPHEGGAGHGAGSGGCRGWQPRMWALFEDPYSSRAARVVAFASLFFILVSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ERELALQRLGPHEGGAGHGAGSGGCRGWQPRMWALFEDPYSSRAARVVAFASLFFILVSI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 TTFCLETHEAFNIDRNVTEILRVGNITSVHFRREVETEPILTYIEGVCVLWFTLEFLVRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TTFCLETHEAFNIDRNVTEILRVGNITSVHFRREVETEPILTYIEGVCVLWFTLEFLVRI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 VCCPDTLDFVKNLLNIIDFVAILPFYLEVGLSGLSSKAARDVLGFLRVVRFVRILRIFKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VCCPDTLDFVKNLLNIIDFVAILPFYLEVGLSGLSSKAARDVLGFLRVVRFVRILRIFKL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 TRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGARPSDPRGNDHTDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGARPSDPRGNDHTDF
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE4 KNIPIGFWWAVVTMTTLGYGDMYPKTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KNIPIGFWWAVVTMTTLGYGDMYPKTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE4 LAMAKQKLPKKRKKHVPRPAQLESPMYCKSEETSPRDSTYSDTSPPAREEGMIERKRADS
::::::::::::::::::::::::::::::::::::::: ::::::::::::::::::::
NP_001 LAMAKQKLPKKRKKHVPRPAQLESPMYCKSEETSPRDSTCSDTSPPAREEGMIERKRADS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE4 KQNGDANAVLSDEEGAGLTQPLASSPTPEERRALRRSTTRDRNKKAAACFLLSTGDYACA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KQNGDANAVLSDEEGAGLTQPLASSPTPEERRALRRSTTRDRNKKAAACFLLSTGDYACA
550 560 570 580 590 600
610 620 630
pF1KE4 DGSVRKGTFVLRDLPLQHSPEAACPPTAGTLFLPH
:::::: :
NP_001 DGSVRKETCQDALSSNYAQAEVLTLS
610 620
>>XP_006710690 (OMIM: 176265) PREDICTED: potassium volta (624 aa)
initn: 4108 init1: 4108 opt: 4109 Z-score: 3636.8 bits: 683.1 E(85289): 7.8e-196
Smith-Waterman score: 4109; 97.9% identity (98.9% similar) in 621 aa overlap (1-619:1-621)
10 20 30 40 50 60
pF1KE4 MISSVCVSSYRGRKSGNKPPSKTCLKEEMAKGEASEKIIINVGGTRHETYRSTLRTLPGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MISSVCVSSYRGRKSGNKPPSKTCLKEEMAKGEASEKIIINVGGTRHETYRSTLRTLPGT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 RLAWLADPDGGGRPETDGGGVGSSGSSGGGGCEFFFDRHPGVFAYVLNYYRTGKLHCPAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RLAWLADPDGGGRPETDGGGVGSSGSSGGGGCEFFFDRHPGVFAYVLNYYRTGKLHCPAD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 VCGPLFEEELTFWGIDETDVEPCCWMTYRQHRDAEEALDIFESPDGGGSGAGPSDEAGDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VCGPLFEEELTFWGIDETDVEPCCWMTYRQHRDAEEALDIFESPDGGGSGAGPSDEAGDD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 ERELALQRLGPHEGGAGHGAGSGGCRGWQPRMWALFEDPYSSRAARVVAFASLFFILVSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ERELALQRLGPHEGGAGHGAGSGGCRGWQPRMWALFEDPYSSRAARVVAFASLFFILVSI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 TTFCLETHEAFNIDRNVTEILRVGNITSVHFRREVETEPILTYIEGVCVLWFTLEFLVRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TTFCLETHEAFNIDRNVTEILRVGNITSVHFRREVETEPILTYIEGVCVLWFTLEFLVRI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 VCCPDTLDFVKNLLNIIDFVAILPFYLEVGLSGLSSKAARDVLGFLRVVRFVRILRIFKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VCCPDTLDFVKNLLNIIDFVAILPFYLEVGLSGLSSKAARDVLGFLRVVRFVRILRIFKL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 TRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGARPSDPRGNDHTDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGARPSDPRGNDHTDF
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE4 KNIPIGFWWAVVTMTTLGYGDMYPKTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KNIPIGFWWAVVTMTTLGYGDMYPKTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE4 LAMAKQKLPKKRKKHVPRPAQLESPMYCKSEETSPRDSTYSDTSPPAREEGMIERKRADS
::::::::::::::::::::::::::::::::::::::: ::::::::::::::::::::
XP_006 LAMAKQKLPKKRKKHVPRPAQLESPMYCKSEETSPRDSTCSDTSPPAREEGMIERKRADS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE4 KQNGDANAVLSDEEGAGLTQPLASSPTPEERRALRRSTTRDRNKKAAACFLLSTGDYACA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KQNGDANAVLSDEEGAGLTQPLASSPTPEERRALRRSTTRDRNKKAAACFLLSTGDYACA
550 560 570 580 590 600
610 620 630
pF1KE4 DGSVRK-GTFVLRD-LPLQHSPEAACPPTAGTLFLPH
:::::: :. . .:..:.
XP_006 DGSVRKEGNVEPKACVPVSHTCAL
610 620
>>XP_006710688 (OMIM: 176265) PREDICTED: potassium volta (618 aa)
initn: 4108 init1: 4108 opt: 4108 Z-score: 3636.0 bits: 682.9 E(85289): 8.7e-196
Smith-Waterman score: 4108; 99.8% identity (99.8% similar) in 606 aa overlap (1-606:1-606)
10 20 30 40 50 60
pF1KE4 MISSVCVSSYRGRKSGNKPPSKTCLKEEMAKGEASEKIIINVGGTRHETYRSTLRTLPGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MISSVCVSSYRGRKSGNKPPSKTCLKEEMAKGEASEKIIINVGGTRHETYRSTLRTLPGT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 RLAWLADPDGGGRPETDGGGVGSSGSSGGGGCEFFFDRHPGVFAYVLNYYRTGKLHCPAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RLAWLADPDGGGRPETDGGGVGSSGSSGGGGCEFFFDRHPGVFAYVLNYYRTGKLHCPAD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 VCGPLFEEELTFWGIDETDVEPCCWMTYRQHRDAEEALDIFESPDGGGSGAGPSDEAGDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VCGPLFEEELTFWGIDETDVEPCCWMTYRQHRDAEEALDIFESPDGGGSGAGPSDEAGDD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 ERELALQRLGPHEGGAGHGAGSGGCRGWQPRMWALFEDPYSSRAARVVAFASLFFILVSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ERELALQRLGPHEGGAGHGAGSGGCRGWQPRMWALFEDPYSSRAARVVAFASLFFILVSI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 TTFCLETHEAFNIDRNVTEILRVGNITSVHFRREVETEPILTYIEGVCVLWFTLEFLVRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TTFCLETHEAFNIDRNVTEILRVGNITSVHFRREVETEPILTYIEGVCVLWFTLEFLVRI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 VCCPDTLDFVKNLLNIIDFVAILPFYLEVGLSGLSSKAARDVLGFLRVVRFVRILRIFKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VCCPDTLDFVKNLLNIIDFVAILPFYLEVGLSGLSSKAARDVLGFLRVVRFVRILRIFKL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 TRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGARPSDPRGNDHTDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGARPSDPRGNDHTDF
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE4 KNIPIGFWWAVVTMTTLGYGDMYPKTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KNIPIGFWWAVVTMTTLGYGDMYPKTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE4 LAMAKQKLPKKRKKHVPRPAQLESPMYCKSEETSPRDSTYSDTSPPAREEGMIERKRADS
::::::::::::::::::::::::::::::::::::::: ::::::::::::::::::::
XP_006 LAMAKQKLPKKRKKHVPRPAQLESPMYCKSEETSPRDSTCSDTSPPAREEGMIERKRADS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE4 KQNGDANAVLSDEEGAGLTQPLASSPTPEERRALRRSTTRDRNKKAAACFLLSTGDYACA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KQNGDANAVLSDEEGAGLTQPLASSPTPEERRALRRSTTRDRNKKAAACFLLSTGDYACA
550 560 570 580 590 600
610 620 630
pF1KE4 DGSVRKGTFVLRDLPLQHSPEAACPPTAGTLFLPH
::::::
XP_006 DGSVRKALSSAEEALCSH
610
>>NP_001106212 (OMIM: 176258,616187) potassium voltage-g (585 aa)
initn: 2654 init1: 1787 opt: 2648 Z-score: 2347.2 bits: 444.4 E(85289): 5.3e-124
Smith-Waterman score: 2648; 71.3% identity (84.0% similar) in 586 aa overlap (29-606:1-564)
10 20 30 40 50 60
pF1KE4 MISSVCVSSYRGRKSGNKPPSKTCLKEEMAKGEASEKIIINVGGTRHETYRSTLRTLPGT
:..:. ::.:.::::::::.::::::::::::
NP_001 MGQGDESERIVINVGGTRHQTYRSTLRTLPGT
10 20 30
70 80 90 100 110 120
pF1KE4 RLAWLADPDGGGRPETDGGGVGSSGSSGGGGCEFFFDRHPGVFAYVLNYYRTGKLHCPAD
::::::.::. .. . : . ::::::::::::..::::::::::::::
NP_001 RLAWLAEPDAHSHFDYDPRAD-----------EFFFDRHPGVFAHILNYYRTGKLHCPAD
40 50 60 70 80
130 140 150 160 170
pF1KE4 VCGPLFEEELTFWGIDETDVEPCCWMTYRQHRDAEEALDIFE-SP-DGGGSGA---GPSD
:::::.::::.:::::::::::::::::::::::::::: : .: :.... : ::.:
NP_001 VCGPLYEEELAFWGIDETDVEPCCWMTYRQHRDAEEALDSFGGAPLDNSADDADADGPGD
90 100 110 120 130 140
180 190 200 210 220 230
pF1KE4 EAGDDERELAL-QRLGPHEGGAGHGAGSGGCRGWQPRMWALFEDPYSSRAARVVAFASLF
.:: : :: . .::. .. :. .: : ::::.::::::::::: :: :::::::
NP_001 -SGDGEDELEMTKRLALSDSPDGRPGGFW--RRWQPRIWALFEDPYSSRYARYVAFASLF
150 160 170 180 190
240 250 260 270 280 290
pF1KE4 FILVSITTFCLETHEAFNIDRNVTEILRVGNITSVHFRREVETEPILTYIEGVCVLWFTL
::::::::::::::: :: : ::: : : :.:.. ::.::: .:::::::::.:::.
NP_001 FILVSITTFCLETHERFNPIVNKTEIENVRNGTQVRYYREAETEAFLTYIEGVCVVWFTF
200 210 220 230 240 250
300 310 320 330 340 350
pF1KE4 EFLVRIVCCPDTLDFVKNLLNIIDFVAILPFYLEVGLSGLSSKAARDVLGFLRVVRFVRI
:::.:.. ::. ..:.:: ::::::::::::::::::::::::::.::::::::::::::
NP_001 EFLMRVIFCPNKVEFIKNSLNIIDFVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRI
260 270 280 290 300 310
360 370 380 390 400 410
pF1KE4 LRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGARPSDPRG
:::::::::::::::::::::::::::::::::::::::::::::::::::::.:.:: .
NP_001 LRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGAQPNDPSA
320 330 340 350 360 370
420 430 440 450 460 470
pF1KE4 NDHTDFKNIPIGFWWAVVTMTTLGYGDMYPKTWSGMLVGALCALAGVLTIAMPVPVIVNN
..:: :::::::::::::::::::::::::.:::::::::::::::::::::::::::::
NP_001 SEHTHFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNN
380 390 400 410 420 430
480 490 500 510 520 530
pF1KE4 FGMYYSLAMAKQKLPKKRKKHVPRPAQLESPMYCKSEETSPRDSTYSDTSPPAREEGMIE
:::::::::::::::::.:::.::: :: :: :::: .::. :: ::: : :.:: ..:
NP_001 FGMYYSLAMAKQKLPKKKKKHIPRPPQLGSPNYCKSVVNSPHHSTQSDTCPLAQEE-ILE
440 450 460 470 480 490
540 550 560 570 580 590
pF1KE4 RKRADSKQNGD-ANAVLSDEEGAGLTQPLASSPTPEERRALRRSTTRDRNKKAAACFLLS
.::::: ::. :.:.:..:. . : : ::.: . :: ::.: . :::::
NP_001 INRADSKLNGEVAKAALANEDCPHIDQAL----TPDEGLPFTRSGTRERY---GPCFLLS
500 510 520 530 540 550
600 610 620 630
pF1KE4 TGDYACADGS-VRKGTFVLRDLPLQHSPEAACPPTAGTLFLPH
::.::: :. .::
NP_001 TGEYACPPGGGMRKDLCKESPVIAKYMPTEAVRVT
560 570 580
>>NP_004967 (OMIM: 176258,616187) potassium voltage-gate (511 aa)
initn: 2490 init1: 1787 opt: 2503 Z-score: 2219.9 bits: 420.6 E(85289): 6.5e-117
Smith-Waterman score: 2503; 74.6% identity (86.1% similar) in 519 aa overlap (29-541:1-504)
10 20 30 40 50 60
pF1KE4 MISSVCVSSYRGRKSGNKPPSKTCLKEEMAKGEASEKIIINVGGTRHETYRSTLRTLPGT
:..:. ::.:.::::::::.::::::::::::
NP_004 MGQGDESERIVINVGGTRHQTYRSTLRTLPGT
10 20 30
70 80 90 100 110 120
pF1KE4 RLAWLADPDGGGRPETDGGGVGSSGSSGGGGCEFFFDRHPGVFAYVLNYYRTGKLHCPAD
::::::.::. .. . : . ::::::::::::..::::::::::::::
NP_004 RLAWLAEPDAHSHFDYDPRAD-----------EFFFDRHPGVFAHILNYYRTGKLHCPAD
40 50 60 70 80
130 140 150 160 170
pF1KE4 VCGPLFEEELTFWGIDETDVEPCCWMTYRQHRDAEEALDIFE-SP-DGGGSGA---GPSD
:::::.::::.:::::::::::::::::::::::::::: : .: :.... : ::.:
NP_004 VCGPLYEEELAFWGIDETDVEPCCWMTYRQHRDAEEALDSFGGAPLDNSADDADADGPGD
90 100 110 120 130 140
180 190 200 210 220 230
pF1KE4 EAGDDERELAL-QRLGPHEGGAGHGAGSGGCRGWQPRMWALFEDPYSSRAARVVAFASLF
.:: : :: . .::. .. :. .: : ::::.::::::::::: :: :::::::
NP_004 -SGDGEDELEMTKRLALSDSPDGRPGGFW--RRWQPRIWALFEDPYSSRYARYVAFASLF
150 160 170 180 190
240 250 260 270 280 290
pF1KE4 FILVSITTFCLETHEAFNIDRNVTEILRVGNITSVHFRREVETEPILTYIEGVCVLWFTL
::::::::::::::: :: : ::: : : :.:.. ::.::: .:::::::::.:::.
NP_004 FILVSITTFCLETHERFNPIVNKTEIENVRNGTQVRYYREAETEAFLTYIEGVCVVWFTF
200 210 220 230 240 250
300 310 320 330 340 350
pF1KE4 EFLVRIVCCPDTLDFVKNLLNIIDFVAILPFYLEVGLSGLSSKAARDVLGFLRVVRFVRI
:::.:.. ::. ..:.:: ::::::::::::::::::::::::::.::::::::::::::
NP_004 EFLMRVIFCPNKVEFIKNSLNIIDFVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRI
260 270 280 290 300 310
360 370 380 390 400 410
pF1KE4 LRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGARPSDPRG
:::::::::::::::::::::::::::::::::::::::::::::::::::::.:.:: .
NP_004 LRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGAQPNDPSA
320 330 340 350 360 370
420 430 440 450 460 470
pF1KE4 NDHTDFKNIPIGFWWAVVTMTTLGYGDMYPKTWSGMLVGALCALAGVLTIAMPVPVIVNN
..:: :::::::::::::::::::::::::.:::::::::::::::::::::::::::::
NP_004 SEHTHFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNN
380 390 400 410 420 430
480 490 500 510 520 530
pF1KE4 FGMYYSLAMAKQKLPKKRKKHVPRPAQLESPMYCKSEETSPRDSTYSDTSPPAREEGMIE
:::::::::::::::::.:::.::: :: :: :::: .::. :: ::: : :.:: ..:
NP_004 FGMYYSLAMAKQKLPKKKKKHIPRPPQLGSPNYCKSVVNSPHHSTQSDTCPLAQEE-ILE
440 450 460 470 480 490
540 550 560 570 580 590
pF1KE4 RKRADSKQNGDANAVLSDEEGAGLTQPLASSPTPEERRALRRSTTRDRNKKAAACFLLST
.:: :
NP_004 INRAGRKPLRGMSI
500 510
>>XP_011518382 (OMIM: 176258,616187) PREDICTED: potassiu (535 aa)
initn: 2490 init1: 1787 opt: 2499 Z-score: 2216.1 bits: 420.0 E(85289): 1.1e-116
Smith-Waterman score: 2499; 74.8% identity (86.4% similar) in 516 aa overlap (29-538:1-501)
10 20 30 40 50 60
pF1KE4 MISSVCVSSYRGRKSGNKPPSKTCLKEEMAKGEASEKIIINVGGTRHETYRSTLRTLPGT
:..:. ::.:.::::::::.::::::::::::
XP_011 MGQGDESERIVINVGGTRHQTYRSTLRTLPGT
10 20 30
70 80 90 100 110 120
pF1KE4 RLAWLADPDGGGRPETDGGGVGSSGSSGGGGCEFFFDRHPGVFAYVLNYYRTGKLHCPAD
::::::.::. .. . : . ::::::::::::..::::::::::::::
XP_011 RLAWLAEPDAHSHFDYDPRA-----------DEFFFDRHPGVFAHILNYYRTGKLHCPAD
40 50 60 70 80
130 140 150 160 170
pF1KE4 VCGPLFEEELTFWGIDETDVEPCCWMTYRQHRDAEEALDIFE-SP-DGGGSGA---GPSD
:::::.::::.:::::::::::::::::::::::::::: : .: :.... : ::.:
XP_011 VCGPLYEEELAFWGIDETDVEPCCWMTYRQHRDAEEALDSFGGAPLDNSADDADADGPGD
90 100 110 120 130 140
180 190 200 210 220 230
pF1KE4 EAGDDERELAL-QRLGPHEGGAGHGAGSGGCRGWQPRMWALFEDPYSSRAARVVAFASLF
.:: : :: . .::. .. :. .: : ::::.::::::::::: :: :::::::
XP_011 -SGDGEDELEMTKRLALSDSPDGRPGGFW--RRWQPRIWALFEDPYSSRYARYVAFASLF
150 160 170 180 190
240 250 260 270 280 290
pF1KE4 FILVSITTFCLETHEAFNIDRNVTEILRVGNITSVHFRREVETEPILTYIEGVCVLWFTL
::::::::::::::: :: : ::: : : :.:.. ::.::: .:::::::::.:::.
XP_011 FILVSITTFCLETHERFNPIVNKTEIENVRNGTQVRYYREAETEAFLTYIEGVCVVWFTF
200 210 220 230 240 250
300 310 320 330 340 350
pF1KE4 EFLVRIVCCPDTLDFVKNLLNIIDFVAILPFYLEVGLSGLSSKAARDVLGFLRVVRFVRI
:::.:.. ::. ..:.:: ::::::::::::::::::::::::::.::::::::::::::
XP_011 EFLMRVIFCPNKVEFIKNSLNIIDFVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRI
260 270 280 290 300 310
360 370 380 390 400 410
pF1KE4 LRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGARPSDPRG
:::::::::::::::::::::::::::::::::::::::::::::::::::::.:.:: .
XP_011 LRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGAQPNDPSA
320 330 340 350 360 370
420 430 440 450 460 470
pF1KE4 NDHTDFKNIPIGFWWAVVTMTTLGYGDMYPKTWSGMLVGALCALAGVLTIAMPVPVIVNN
..:: :::::::::::::::::::::::::.:::::::::::::::::::::::::::::
XP_011 SEHTHFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNN
380 390 400 410 420 430
480 490 500 510 520 530
pF1KE4 FGMYYSLAMAKQKLPKKRKKHVPRPAQLESPMYCKSEETSPRDSTYSDTSPPAREEGMIE
:::::::::::::::::.:::.::: :: :: :::: .::. :: ::: : :.:: ..:
XP_011 FGMYYSLAMAKQKLPKKKKKHIPRPPQLGSPNYCKSVVNSPHHSTQSDTCPLAQEE-ILE
440 450 460 470 480 490
540 550 560 570 580 590
pF1KE4 RKRADSKQNGDANAVLSDEEGAGLTQPLASSPTPEERRALRRSTTRDRNKKAAACFLLST
.::
XP_011 INRAGISKEQMTQRRMTALSKKECQMLISAHFKPGNHL
500 510 520 530
>>NP_001247428 (OMIM: 176256) potassium voltage-gated ch (583 aa)
initn: 2175 init1: 1435 opt: 2359 Z-score: 2092.0 bits: 397.2 E(85289): 8.7e-110
Smith-Waterman score: 2486; 68.1% identity (79.6% similar) in 593 aa overlap (29-579:1-577)
10 20 30 40 50 60
pF1KE4 MISSVCVSSYRGRKSGNKPPSKTCLKEEMAKGEASEKIIINVGGTRHETYRSTLRTLPGT
:.: : .:..:.::::::::::::::.:::::
NP_001 MGKIENNERVILNVGGTRHETYRSTLKTLPGT
10 20 30
70 80
pF1KE4 RLAWLA--DPDG------GGR---------------PETDG------GGVGSSGSSGG--
::: :: .: : : . : . : ::.:. .: ::
NP_001 RLALLASSEPPGDCLTTAGDKLQPSPPPLSPPPRAPPLSPGPGGCFEGGAGNCSSRGGRA
40 50 60 70 80 90
90 100 110 120 130 140
pF1KE4 -----GGCEFFFDRHPGVFAYVLNYYRTGKLHCPADVCGPLFEEELTFWGIDETDVEPCC
:: ::::::::::::::::::::::::::::::::::::::.:::::::::::::
NP_001 SDHPGGGREFFFDRHPGVFAYVLNYYRTGKLHCPADVCGPLFEEELAFWGIDETDVEPCC
100 110 120 130 140 150
150 160 170 180 190 200
pF1KE4 WMTYRQHRDAEEALDIFESPDGGGSGAGPSDEAGDDERELALQRLGPHEGGAGHGAGSGG
::::::::::::::::::.:: :. . :::: .:: .::: : .:: :. .:
NP_001 WMTYRQHRDAEEALDIFETPDLIGG------DPGDDE-DLAAKRLGI-EDAAGLGGPDGK
160 170 180 190 200
210 220 230 240 250 260
pF1KE4 CRGW---QPRMWALFEDPYSSRAARVVAFASLFFILVSITTFCLETHEAFNIDRNVTEIL
: :::::::::::::::::: .::::::::::::::::::::::::: .: ::
NP_001 SGRWRRLQPRMWALFEDPYSSRAARFIAFASLFFILVSITTFCLETHEAFNIVKNKTE--
210 220 230 240 250 260
270 280 290 300 310 320
pF1KE4 RVGNITSVHFRREVETEPILTYIEGVCVLWFTLEFLVRIVCCPDTLDFVKNLLNIIDFVA
: : ::: .. :.::.: :::.:::::.:::.::::::: :. :.:.:::::::::::
NP_001 PVINGTSVVLQYEIETDPALTYVEGVCVVWFTFEFLVRIVFSPNKLEFIKNLLNIIDFVA
270 280 290 300 310 320
330 340 350 360 370 380
pF1KE4 ILPFYLEVGLSGLSSKAARDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEF
::::::::::::::::::.:::::::::::::::::::::::::::::::::::::::::
NP_001 ILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEF
330 340 350 360 370 380
390 400 410 420 430 440
pF1KE4 LLLIIFLALGVLIFATMIYYAERIGARPSDPRGNDHTDFKNIPIGFWWAVVTMTTLGYGD
:::::::::::::::::::::::.::.:.:: ...::.::::::::::::::::::::::
NP_001 LLLIIFLALGVLIFATMIYYAERVGAQPNDPSASEHTQFKNIPIGFWWAVVTMTTLGYGD
390 400 410 420 430 440
450 460 470 480 490 500
pF1KE4 MYPKTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKRKKHVPRPAQ
:::.::::::::::::::::::::::::::::::::::::::::::::.:::::.: :
NP_001 MYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPRKRKKHIPPAPQ
450 460 470 480 490 500
510 520 530 540 550 560
pF1KE4 LESPMYCKSEETSPRDSTYSDTSPPAREEGMIERKRADSKQNGDANAVLSDEEGAGLTQP
:: .::.: . .:: ::: .... ..:..:. ... . : . . .: .:
NP_001 ASSPTFCKTELNMACNSTQSDTCL-GKDNRLLEHNRSGYEKSRSLNNIAGLAGNALRLSP
510 520 530 540 550 560
570 580 590 600 610
pF1KE4 LAS---SPTPEERRALRRSTTRDRNKKAAACFLLSTGDYACADGSVRKGTFVLRDLPLQH
..: :: : :::: .
NP_001 VTSPYNSPCP-----LRRSRSPIPSIL
570 580
>>NP_715624 (OMIM: 176256) potassium voltage-gated chann (558 aa)
initn: 2175 init1: 1435 opt: 2346 Z-score: 2080.8 bits: 395.0 E(85289): 3.7e-109
Smith-Waterman score: 2473; 71.5% identity (82.0% similar) in 551 aa overlap (29-540:1-540)
10 20 30 40 50 60
pF1KE4 MISSVCVSSYRGRKSGNKPPSKTCLKEEMAKGEASEKIIINVGGTRHETYRSTLRTLPGT
:.: : .:..:.::::::::::::::.:::::
NP_715 MGKIENNERVILNVGGTRHETYRSTLKTLPGT
10 20 30
70 80
pF1KE4 RLAWLA--DPDG------GGR---------------PETDG------GGVGSSGSSGG--
::: :: .: : : . : . : ::.:. .: ::
NP_715 RLALLASSEPPGDCLTTAGDKLQPSPPPLSPPPRAPPLSPGPGGCFEGGAGNCSSRGGRA
40 50 60 70 80 90
90 100 110 120 130 140
pF1KE4 -----GGCEFFFDRHPGVFAYVLNYYRTGKLHCPADVCGPLFEEELTFWGIDETDVEPCC
:: ::::::::::::::::::::::::::::::::::::::.:::::::::::::
NP_715 SDHPGGGREFFFDRHPGVFAYVLNYYRTGKLHCPADVCGPLFEEELAFWGIDETDVEPCC
100 110 120 130 140 150
150 160 170 180 190 200
pF1KE4 WMTYRQHRDAEEALDIFESPDGGGSGAGPSDEAGDDERELALQRLGPHEGGAGHGAGSGG
::::::::::::::::::.:: :. . :::: .:: .::: : .:: :. .:
NP_715 WMTYRQHRDAEEALDIFETPDLIGG------DPGDDE-DLAAKRLGI-EDAAGLGGPDGK
160 170 180 190 200
210 220 230 240 250 260
pF1KE4 CRGW---QPRMWALFEDPYSSRAARVVAFASLFFILVSITTFCLETHEAFNIDRNVTEIL
: :::::::::::::::::: .::::::::::::::::::::::::: .: ::
NP_715 SGRWRRLQPRMWALFEDPYSSRAARFIAFASLFFILVSITTFCLETHEAFNIVKNKTEP-
210 220 230 240 250 260
270 280 290 300 310 320
pF1KE4 RVGNITSVHFRREVETEPILTYIEGVCVLWFTLEFLVRIVCCPDTLDFVKNLLNIIDFVA
: : ::: .. :.::.: :::.:::::.:::.::::::: :. :.:.:::::::::::
NP_715 -VINGTSVVLQYEIETDPALTYVEGVCVVWFTFEFLVRIVFSPNKLEFIKNLLNIIDFVA
270 280 290 300 310 320
330 340 350 360 370 380
pF1KE4 ILPFYLEVGLSGLSSKAARDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEF
::::::::::::::::::.:::::::::::::::::::::::::::::::::::::::::
NP_715 ILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEF
330 340 350 360 370 380
390 400 410 420 430 440
pF1KE4 LLLIIFLALGVLIFATMIYYAERIGARPSDPRGNDHTDFKNIPIGFWWAVVTMTTLGYGD
:::::::::::::::::::::::.::.:.:: ...::.::::::::::::::::::::::
NP_715 LLLIIFLALGVLIFATMIYYAERVGAQPNDPSASEHTQFKNIPIGFWWAVVTMTTLGYGD
390 400 410 420 430 440
450 460 470 480 490 500
pF1KE4 MYPKTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKRKKHVPRPAQ
:::.::::::::::::::::::::::::::::::::::::::::::::.:::::.: :
NP_715 MYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPRKRKKHIPPAPQ
450 460 470 480 490 500
510 520 530 540 550 560
pF1KE4 LESPMYCKSEETSPRDSTYSDTSPPAREEGMIERKRADSKQNGDANAVLSDEEGAGLTQP
:: .::.: . .:: ::: .... ..:..:.:.
NP_715 ASSPTFCKTELNMACNSTQSDTCL-GKDNRLLEHNRSDNCKEVVITGYTQAEARSLT
510 520 530 540 550
570 580 590 600 610 620
pF1KE4 LASSPTPEERRALRRSTTRDRNKKAAACFLLSTGDYACADGSVRKGTFVLRDLPLQHSPE
635 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 03:36:56 2016 done: Sun Nov 6 03:36:58 2016
Total Scan time: 12.290 Total Display time: 0.160
Function used was FASTA [36.3.4 Apr, 2011]