Result of FASTA (ccds) for
pFN21AE4170
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE4170, 621 aa
1>>>pF1KE4170 621 - 621 aa - 621 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.1527+/-0.00106; mu= 14.6600+/- 0.063
mean_var=85.3849+/-17.363, 0's: 0 Z-trim(104.6): 49 B-trim: 0 in 0/49
Lambda= 0.138798
statistics sampled from 7935 (7973) to 7935 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.616), E-opt: 0.2 (0.245), width: 16
Scan time: 3.440
The best scores are: opt bits E(32554)
CCDS5041.1 FBXL4 gene_id:26235|Hs108|chr6 ( 621) 4209 853.4 0
CCDS54116.1 FBXL20 gene_id:84961|Hs108|chr17 ( 404) 342 79.0 1.4e-14
CCDS64129.1 FBXL7 gene_id:23194|Hs108|chr5 ( 444) 315 73.6 6.4e-13
CCDS54833.1 FBXL7 gene_id:23194|Hs108|chr5 ( 491) 315 73.6 7e-13
>>CCDS5041.1 FBXL4 gene_id:26235|Hs108|chr6 (621 aa)
initn: 4209 init1: 4209 opt: 4209 Z-score: 4557.3 bits: 853.4 E(32554): 0
Smith-Waterman score: 4209; 100.0% identity (100.0% similar) in 621 aa overlap (1-621:1-621)
10 20 30 40 50 60
pF1KE4 MSPVFPMLTVLTMFYYICLRRRARTATRGEMMNTHRAIESNSQTSPLNAEVVQYAKEVVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS50 MSPVFPMLTVLTMFYYICLRRRARTATRGEMMNTHRAIESNSQTSPLNAEVVQYAKEVVD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 FSSHYGSENSMSYTMWNLAGVPNVFPSSGDFTQTAVFRTYGTWWDQCPSASLPFKRTPPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS50 FSSHYGSENSMSYTMWNLAGVPNVFPSSGDFTQTAVFRTYGTWWDQCPSASLPFKRTPPN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 FQSQDYVELTFEQQVYPTAVHVLETYHPGAVIRILACSANPYSPNPPAEVRWEILWSERP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS50 FQSQDYVELTFEQQVYPTAVHVLETYHPGAVIRILACSANPYSPNPPAEVRWEILWSERP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 TKVNASQARQFKPCIKQINFPTNLIRLEVNSSLLEYYTELDAVVLHGVKDKPVLSLKTSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS50 TKVNASQARQFKPCIKQINFPTNLIRLEVNSSLLEYYTELDAVVLHGVKDKPVLSLKTSL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 IDMNDIEDDAYAEKDGCGMDSLNKKFSSAVLGEGPNNGYFDKLPYELIQLILNHLTLPDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS50 IDMNDIEDDAYAEKDGCGMDSLNKKFSSAVLGEGPNNGYFDKLPYELIQLILNHLTLPDL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 CRLAQTCKLLSQHCCDPLQYIHLNLQPYWAKLDDTSLEFLQSRCTLVQWLNLSWTGNRGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS50 CRLAQTCKLLSQHCCDPLQYIHLNLQPYWAKLDDTSLEFLQSRCTLVQWLNLSWTGNRGF
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 ISVAGFSRFLKVCGSELVRLELSCSHFLNETCLEVISEMCPNLQALNLSSCDKLPPQAFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS50 ISVAGFSRFLKVCGSELVRLELSCSHFLNETCLEVISEMCPNLQALNLSSCDKLPPQAFN
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE4 HIAKLCSLKRLVLYRTKVEQTALLSILNFCSELQHLSLGSCVMIEDYDVIASMIGAKCKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS50 HIAKLCSLKRLVLYRTKVEQTALLSILNFCSELQHLSLGSCVMIEDYDVIASMIGAKCKK
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE4 LRTLDLWRCKNITENGIAELASGCPLLEELDLGWCPTLQSSTGCFTRLAHQLPNLQKLFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS50 LRTLDLWRCKNITENGIAELASGCPLLEELDLGWCPTLQSSTGCFTRLAHQLPNLQKLFL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE4 TANRSVCDTDIDELACNCTRLQQLDILGTRMVSPASLRKLLESCKDLSLLDVSFCSQIDN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS50 TANRSVCDTDIDELACNCTRLQQLDILGTRMVSPASLRKLLESCKDLSLLDVSFCSQIDN
550 560 570 580 590 600
610 620
pF1KE4 RAVLELNASFPKVFIKKSFTQ
:::::::::::::::::::::
CCDS50 RAVLELNASFPKVFIKKSFTQ
610 620
>>CCDS54116.1 FBXL20 gene_id:84961|Hs108|chr17 (404 aa)
initn: 401 init1: 143 opt: 342 Z-score: 375.3 bits: 79.0 E(32554): 1.4e-14
Smith-Waterman score: 392; 27.0% identity (56.6% similar) in 371 aa overlap (282-619:27-381)
260 270 280 290 300 310
pF1KE4 AEKDGCGMDSLNKKFSSAVLGEGPNNGYFDKLPYELIQLILNHLTLPDLCRLAQTCKLLS
::: ::. :.. : . ::: ::. . .
CCDS54 MRRDVNGVTKSRFEMFSNSDEAVINKKLPKELLLRIFSFLDVVTLCRCAQVSRAWN
10 20 30 40 50
320 330 340 350 360
pF1KE4 QHCCDPLQYIHLNLQPYWAKLDDTSLEFLQSRCT-LVQWLNLSWTGNRGFISVA--GFSR
: .. ...: . .. .: ...:: ... :.: :: ..:. ..
CCDS54 VLALDGSNWQRIDLFDFQRDIEGRVVENISKRCGGFLRKLSL-----RGCLGVGDNALRT
60 70 80 90 100 110
370 380 390 400 410 420
pF1KE4 FLKVCGS-ELVRLELSCSHFLNETCLEVISEMCPNLQALNLSSCDKLPPQAFNHIAKLCS
: . : . :.. :. .:.. . .: :: :. ::.: ::.. .... ... :.
CCDS54 FAQNCRNIEVLNLN-GCTKTTD-------AEGCPLLEQLNISWCDQVTKDGIQALVRGCG
120 130 140 150 160
430 440 450 460
pF1KE4 -LKRLVLYR-TKVEQTALLSILNFCSELQHLSLGSCVMIEDY------------------
:: : : :..:. :: : : :: :.: .:..: :
CCDS54 GLKALFLKGCTQLEDEALKYIGAHCPELVTLNLQTCLQITDEGLITICRGCHKLQSLCAS
170 180 190 200 210 220
470 480 490 500 510 520
pF1KE4 ------DVIASMIGAKCKKLRTLDLWRCKNITENGIAELASGCPLLEELDLGWCPTLQSS
:.: . .: .: .:: :.. ::...:. :.. :: .: ::..:: : . .:
CCDS54 GCSNITDAILNALGQNCPRLRILEVARCSQLTDVGFTTLARNCHELEKMDLEECVQITDS
230 240 250 260 270 280
530 540 550 560 570
pF1KE4 TGCFTRLAHQLPNLQKLFLTANRSVCDTDIDEL---ACNCTRLQQLDILGTRMVSPASLR
: . .:. . : :: : :. . . : : .: :: .:. ... . ... :::.
CCDS54 T--LIQLSIHCPRLQVLSLSHCELITDDGIRHLGNGACAHDQLEVIELDNCPLITDASLE
290 300 310 320 330 340
580 590 600 610 620
pF1KE4 KLLESCKDLSLLDVSFCSQIDNRAVLELNASFPKVFIKKSFTQ
.: .::..: ... :.:: .. .: . .:.. .. :
CCDS54 HL-KSCHSLERIELYDCQQITRAGIKRLRTHLPNIKVHAYFAPVTPPPSVGGSRQRFCRC
350 360 370 380 390 400
CCDS54 CIIL
>>CCDS64129.1 FBXL7 gene_id:23194|Hs108|chr5 (444 aa)
initn: 415 init1: 141 opt: 315 Z-score: 345.4 bits: 73.6 E(32554): 6.4e-13
Smith-Waterman score: 345; 26.4% identity (56.5% similar) in 345 aa overlap (281-603:68-399)
260 270 280 290 300 310
pF1KE4 YAEKDGCGMDSLNKKFSSAVLGEGPNNGYFDKLPYELIQLILNHLTLPDLCRLAQTCKLL
:.:: . . :.. : .::: :..:.
CCDS64 VAMVHSPPPTRLTHPLIRLASRPQKEQASIDRLPDHSMVQIFSFLPTNQLCRCARVCRRW
40 50 60 70 80 90
320 330 340 350
pF1KE4 SQHCCDPLQYIHLNLQPYWAKLDDTSLEFLQSR--------CTLVQWLNLSWT---GNRG
. :: . . : ..: .:. : : : ... ...: .::
CCDS64 YNLAWDPRLWRTIRLTGETINVD-RALKVLTRRLCQDTPNVCLMLETVTVSGCRRLTDRG
100 110 120 130 140 150
360 370 380 390 400 410
pF1KE4 FISVAGFSRFLKVCGSELVRLELS-CSHFLNETCLEVISEMCPNLQALNLSSCDKLPPQA
. ..: : :: :::.: : .. ::. ..:.: .::::. :..:.:.:. .
CCDS64 LYTIAQ-------CCPELRRLEVSGCYNISNEAVFDVVS-LCPNLEHLDVSGCSKVTCIS
160 170 180 190 200
420 430 440 450 460
pF1KE4 FNHIA---------KLCSLKRLVLYRTKV-EQTALLSILNFCSELQHLSLGSCVMIEDYD
... : : :.. : . : :. .: .: :..: :: : :: . :
CCDS64 LTREASIKLSPLHGKQISIRYLDMTDCFVLEDEGLHTIAAHCTQLTHLYLRRCVRLTDEG
210 220 230 240 250 260
470 480 490 500 510 520
pF1KE4 VIASMIGAKCKKLRTLDLWRCKNITENGIAELASGCPLLEELDLGWCPTLQSSTGCFTRL
. .: : ... :.. :. ... :. :.:. :. :... : . ...: . .
CCDS64 LRYLVI--YCASIKELSVSDCRFVSDFGLREIAKLESRLRYLSIAHCGRV-TDVG-IRYV
270 280 290 300 310 320
530 540 550 560 570 580
pF1KE4 AHQLPNLQKLFLTANRSVCDTDIDELACNCTRLQQLDILGTRMVSPASLRKLLESCKDLS
:. .:. : . ... : .. :: :::.:..::: .:: ..:. : .: .:.
CCDS64 AKYCSKLRYLNARGCEGITDHGVEYLAKNCTKLKSLDIGKCPLVSDTGLECLALNCFNLK
330 340 350 360 370 380
590 600 610 620
pF1KE4 LLDVSFCSQIDNRAVLELNASFPKVFIKKSFTQ
:... : .: ....
CCDS64 RLSLKSCESITGQGLQIVAANCFDLQTLNVQDCEVSVEALRFVKRHCKRCVIEHTNPAFF
390 400 410 420 430 440
>>CCDS54833.1 FBXL7 gene_id:23194|Hs108|chr5 (491 aa)
initn: 415 init1: 141 opt: 315 Z-score: 344.7 bits: 73.6 E(32554): 7e-13
Smith-Waterman score: 345; 26.4% identity (56.5% similar) in 345 aa overlap (281-603:115-446)
260 270 280 290 300 310
pF1KE4 YAEKDGCGMDSLNKKFSSAVLGEGPNNGYFDKLPYELIQLILNHLTLPDLCRLAQTCKLL
:.:: . . :.. : .::: :..:.
CCDS54 VAMVHSPPPTRLTHPLIRLASRPQKEQASIDRLPDHSMVQIFSFLPTNQLCRCARVCRRW
90 100 110 120 130 140
320 330 340 350
pF1KE4 SQHCCDPLQYIHLNLQPYWAKLDDTSLEFLQSR--------CTLVQWLNLSWT---GNRG
. :: . . : ..: .:. : : : ... ...: .::
CCDS54 YNLAWDPRLWRTIRLTGETINVD-RALKVLTRRLCQDTPNVCLMLETVTVSGCRRLTDRG
150 160 170 180 190 200
360 370 380 390 400 410
pF1KE4 FISVAGFSRFLKVCGSELVRLELS-CSHFLNETCLEVISEMCPNLQALNLSSCDKLPPQA
. ..: : :: :::.: : .. ::. ..:.: .::::. :..:.:.:. .
CCDS54 LYTIAQ-------CCPELRRLEVSGCYNISNEAVFDVVS-LCPNLEHLDVSGCSKVTCIS
210 220 230 240 250
420 430 440 450 460
pF1KE4 FNHIA---------KLCSLKRLVLYRTKV-EQTALLSILNFCSELQHLSLGSCVMIEDYD
... : : :.. : . : :. .: .: :..: :: : :: . :
CCDS54 LTREASIKLSPLHGKQISIRYLDMTDCFVLEDEGLHTIAAHCTQLTHLYLRRCVRLTDEG
260 270 280 290 300 310
470 480 490 500 510 520
pF1KE4 VIASMIGAKCKKLRTLDLWRCKNITENGIAELASGCPLLEELDLGWCPTLQSSTGCFTRL
. .: : ... :.. :. ... :. :.:. :. :... : . ...: . .
CCDS54 LRYLVI--YCASIKELSVSDCRFVSDFGLREIAKLESRLRYLSIAHCGRV-TDVG-IRYV
320 330 340 350 360 370
530 540 550 560 570 580
pF1KE4 AHQLPNLQKLFLTANRSVCDTDIDELACNCTRLQQLDILGTRMVSPASLRKLLESCKDLS
:. .:. : . ... : .. :: :::.:..::: .:: ..:. : .: .:.
CCDS54 AKYCSKLRYLNARGCEGITDHGVEYLAKNCTKLKSLDIGKCPLVSDTGLECLALNCFNLK
380 390 400 410 420 430
590 600 610 620
pF1KE4 LLDVSFCSQIDNRAVLELNASFPKVFIKKSFTQ
:... : .: ....
CCDS54 RLSLKSCESITGQGLQIVAANCFDLQTLNVQDCEVSVEALRFVKRHCKRCVIEHTNPAFF
440 450 460 470 480 490
621 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 16:33:52 2016 done: Mon Nov 7 16:33:52 2016
Total Scan time: 3.440 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]