Result of FASTA (omim) for
pFN21AE4151
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE4151, 586 aa
1>>>pF1KE4151 586 - 586 aa - 586 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.0252+/-0.000443; mu= 20.5601+/- 0.027
mean_var=86.4744+/-17.753, 0's: 0 Z-trim(111.1): 396 B-trim: 0 in 0/51
Lambda= 0.137921
statistics sampled from 19126 (19583) to 19126 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.584), E-opt: 0.2 (0.23), width: 16
Scan time: 9.790
The best scores are: opt bits E(85289)
NP_001026880 (OMIM: 611119,612943,617055) kelch-li ( 586) 3959 798.6 0
XP_016867928 (OMIM: 611119,612943,617055) PREDICTE ( 564) 3719 750.9 2.6e-216
NP_061334 (OMIM: 611119,612943,617055) kelch-like ( 538) 3665 740.1 4.3e-213
XP_006715819 (OMIM: 611119,612943,617055) PREDICTE ( 551) 3047 617.1 4.6e-176
XP_006715817 (OMIM: 611119,612943,617055) PREDICTE ( 577) 3047 617.2 4.7e-176
XP_006715818 (OMIM: 611119,612943,617055) PREDICTE ( 577) 3047 617.2 4.7e-176
XP_006715816 (OMIM: 611119,612943,617055) PREDICTE ( 599) 3047 617.2 4.9e-176
XP_016867929 (OMIM: 611119,612943,617055) PREDICTE ( 325) 2045 417.5 3.3e-116
XP_016867930 (OMIM: 611119,612943,617055) PREDICTE ( 303) 1805 369.7 7.5e-102
XP_006715820 (OMIM: 611119,612943,617055) PREDICTE ( 338) 1133 236.1 1.4e-61
NP_059111 (OMIM: 605775,614495) kelch-like protein ( 587) 1078 225.4 4.2e-58
NP_001244123 (OMIM: 605775,614495) kelch-like prot ( 555) 1077 225.2 4.6e-58
NP_009177 (OMIM: 605774) kelch-like protein 2 isof ( 593) 1071 224.0 1.1e-57
NP_001154993 (OMIM: 605774) kelch-like protein 2 i ( 597) 1071 224.0 1.1e-57
XP_016863163 (OMIM: 605774) PREDICTED: kelch-like ( 555) 1070 223.8 1.2e-57
XP_011529874 (OMIM: 605774) PREDICTED: kelch-like ( 633) 1041 218.1 7.2e-56
NP_067646 (OMIM: 614522) kelch-like protein 12 iso ( 568) 1030 215.8 3.1e-55
NP_001289980 (OMIM: 614522) kelch-like protein 12 ( 606) 1030 215.8 3.2e-55
XP_011508137 (OMIM: 614522) PREDICTED: kelch-like ( 623) 1030 215.9 3.3e-55
NP_001165125 (OMIM: 608064) kelch-like protein 5 i ( 568) 953 200.5 1.3e-50
NP_001007076 (OMIM: 608064) kelch-like protein 5 i ( 709) 953 200.6 1.5e-50
NP_057074 (OMIM: 608064) kelch-like protein 5 isof ( 755) 953 200.6 1.5e-50
XP_016863764 (OMIM: 608064) PREDICTED: kelch-like ( 788) 953 200.6 1.6e-50
XP_005262712 (OMIM: 608064) PREDICTED: kelch-like ( 789) 953 200.6 1.6e-50
XP_011512003 (OMIM: 608064) PREDICTED: kelch-like ( 788) 951 200.2 2.1e-50
XP_016863765 (OMIM: 608064) PREDICTED: kelch-like ( 788) 951 200.2 2.1e-50
XP_011512002 (OMIM: 608064) PREDICTED: kelch-like ( 788) 951 200.2 2.1e-50
XP_016863763 (OMIM: 608064) PREDICTED: kelch-like ( 804) 948 199.7 3.2e-50
XP_011512001 (OMIM: 608064) PREDICTED: kelch-like ( 804) 948 199.7 3.2e-50
XP_016863762 (OMIM: 608064) PREDICTED: kelch-like ( 804) 948 199.7 3.2e-50
NP_036421 (OMIM: 606016) kelch-like ECH-associated ( 624) 945 198.9 4e-50
XP_011526754 (OMIM: 606016) PREDICTED: kelch-like ( 624) 945 198.9 4e-50
NP_987096 (OMIM: 606016) kelch-like ECH-associated ( 624) 945 198.9 4e-50
XP_005260231 (OMIM: 606016) PREDICTED: kelch-like ( 624) 945 198.9 4e-50
XP_005260230 (OMIM: 606016) PREDICTED: kelch-like ( 624) 945 198.9 4e-50
NP_061990 (OMIM: 300348) kelch-like protein 4 isof ( 718) 942 198.4 6.7e-50
NP_001165899 (OMIM: 611119,612943,617055) kelch-li ( 166) 932 195.8 9.7e-50
XP_016876167 (OMIM: 605332) PREDICTED: kelch-like ( 575) 935 196.9 1.5e-49
NP_065917 (OMIM: 605332) kelch-like protein 1 isof ( 748) 935 197.0 1.8e-49
NP_476503 (OMIM: 300348) kelch-like protein 4 isof ( 720) 932 196.4 2.7e-49
NP_001244124 (OMIM: 605775,614495) kelch-like prot ( 505) 926 195.1 4.8e-49
NP_001154994 (OMIM: 605774) kelch-like protein 2 i ( 505) 917 193.3 1.7e-48
XP_016863165 (OMIM: 605774) PREDICTED: kelch-like ( 505) 917 193.3 1.7e-48
XP_016857484 (OMIM: 614522) PREDICTED: kelch-like ( 471) 879 185.7 3e-46
XP_011508138 (OMIM: 614522) PREDICTED: kelch-like ( 526) 879 185.7 3.2e-46
NP_950240 (OMIM: 608064) kelch-like protein 5 isof ( 694) 851 180.3 1.9e-44
NP_001317953 (OMIM: 605774) kelch-like protein 2 i ( 496) 845 178.9 3.4e-44
XP_011529878 (OMIM: 605774) PREDICTED: kelch-like ( 496) 845 178.9 3.4e-44
NP_001290038 (OMIM: 614522) kelch-like protein 12 ( 467) 839 177.7 7.4e-44
XP_016863164 (OMIM: 605774) PREDICTED: kelch-like ( 415) 838 177.5 7.8e-44
>>NP_001026880 (OMIM: 611119,612943,617055) kelch-like p (586 aa)
initn: 3959 init1: 3959 opt: 3959 Z-score: 4262.3 bits: 798.6 E(85289): 0
Smith-Waterman score: 3959; 100.0% identity (100.0% similar) in 586 aa overlap (1-586:1-586)
10 20 30 40 50 60
pF1KE4 MAASGVEKSSKKKTEKKLAAREEAKLLAGFMGVMNNMRKQKTLCDVILMVQERKIPAHRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAASGVEKSSKKKTEKKLAAREEAKLLAGFMGVMNNMRKQKTLCDVILMVQERKIPAHRV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 VLAAASHFFNLMFTTNMLESKSFEVELKDAEPDIIEQLVEFAYTARISVNSNNVQSLLDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLAAASHFFNLMFTTNMLESKSFEVELKDAEPDIIEQLVEFAYTARISVNSNNVQSLLDA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 ANQYQIEPVKKMCVDFLKEQVDASNCLGISVLAECLDCPELKATADDFIHQHFTEVYKTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ANQYQIEPVKKMCVDFLKEQVDASNCLGISVLAECLDCPELKATADDFIHQHFTEVYKTD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 EFLQLDVKRVTHLLNQDTLTVRAEDQVYDAAVRWLKYDEPNRQPFMVDILAKVRFPLISK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EFLQLDVKRVTHLLNQDTLTVRAEDQVYDAAVRWLKYDEPNRQPFMVDILAKVRFPLISK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 NFLSKTVQAEPLIQDNPECLKMVISGMRYHLLSPEDREELVDGTRPRRKKHDYRIALFGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NFLSKTVQAEPLIQDNPECLKMVISGMRYHLLSPEDREELVDGTRPRRKKHDYRIALFGG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 SQPQSCRYFNPKDYSWTDIRCPFEKRRDAACVFWDNVVYILGGSQLFPIKRMDCYNVVKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SQPQSCRYFNPKDYSWTDIRCPFEKRRDAACVFWDNVVYILGGSQLFPIKRMDCYNVVKD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 SWYSKLGPPTPRDSLAACAAEGKIYTSGGSEVGNSALYLFECYDTRTESWHTKPSMLTQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SWYSKLGPPTPRDSLAACAAEGKIYTSGGSEVGNSALYLFECYDTRTESWHTKPSMLTQR
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE4 CSHGMVEANGLIYVCGGSLGNNVSGRVLNSCEVYDPATETWTELCPMIEARKNHGLVFVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CSHGMVEANGLIYVCGGSLGNNVSGRVLNSCEVYDPATETWTELCPMIEARKNHGLVFVK
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE4 DKIFAVGGQNGLGGLDNVEYYDIKLNEWKMVSPMPWKGVTVKCAAVGSIVYVLAGFQGVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DKIFAVGGQNGLGGLDNVEYYDIKLNEWKMVSPMPWKGVTVKCAAVGSIVYVLAGFQGVG
490 500 510 520 530 540
550 560 570 580
pF1KE4 RLGHILEYNTETDKWVANSKVRAFPVTSCLICVVDTCGANEETLET
::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RLGHILEYNTETDKWVANSKVRAFPVTSCLICVVDTCGANEETLET
550 560 570 580
>>XP_016867928 (OMIM: 611119,612943,617055) PREDICTED: k (564 aa)
initn: 3719 init1: 3719 opt: 3719 Z-score: 4004.4 bits: 750.9 E(85289): 2.6e-216
Smith-Waterman score: 3719; 99.8% identity (100.0% similar) in 547 aa overlap (40-586:18-564)
10 20 30 40 50 60
pF1KE4 SKKKTEKKLAAREEAKLLAGFMGVMNNMRKQKTLCDVILMVQERKIPAHRVVLAAASHFF
.:::::::::::::::::::::::::::::
XP_016 MLGGTDCRTFLTSHINLKKTLCDVILMVQERKIPAHRVVLAAASHFF
10 20 30 40
70 80 90 100 110 120
pF1KE4 NLMFTTNMLESKSFEVELKDAEPDIIEQLVEFAYTARISVNSNNVQSLLDAANQYQIEPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NLMFTTNMLESKSFEVELKDAEPDIIEQLVEFAYTARISVNSNNVQSLLDAANQYQIEPV
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE4 KKMCVDFLKEQVDASNCLGISVLAECLDCPELKATADDFIHQHFTEVYKTDEFLQLDVKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKMCVDFLKEQVDASNCLGISVLAECLDCPELKATADDFIHQHFTEVYKTDEFLQLDVKR
110 120 130 140 150 160
190 200 210 220 230 240
pF1KE4 VTHLLNQDTLTVRAEDQVYDAAVRWLKYDEPNRQPFMVDILAKVRFPLISKNFLSKTVQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VTHLLNQDTLTVRAEDQVYDAAVRWLKYDEPNRQPFMVDILAKVRFPLISKNFLSKTVQA
170 180 190 200 210 220
250 260 270 280 290 300
pF1KE4 EPLIQDNPECLKMVISGMRYHLLSPEDREELVDGTRPRRKKHDYRIALFGGSQPQSCRYF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EPLIQDNPECLKMVISGMRYHLLSPEDREELVDGTRPRRKKHDYRIALFGGSQPQSCRYF
230 240 250 260 270 280
310 320 330 340 350 360
pF1KE4 NPKDYSWTDIRCPFEKRRDAACVFWDNVVYILGGSQLFPIKRMDCYNVVKDSWYSKLGPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NPKDYSWTDIRCPFEKRRDAACVFWDNVVYILGGSQLFPIKRMDCYNVVKDSWYSKLGPP
290 300 310 320 330 340
370 380 390 400 410 420
pF1KE4 TPRDSLAACAAEGKIYTSGGSEVGNSALYLFECYDTRTESWHTKPSMLTQRCSHGMVEAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TPRDSLAACAAEGKIYTSGGSEVGNSALYLFECYDTRTESWHTKPSMLTQRCSHGMVEAN
350 360 370 380 390 400
430 440 450 460 470 480
pF1KE4 GLIYVCGGSLGNNVSGRVLNSCEVYDPATETWTELCPMIEARKNHGLVFVKDKIFAVGGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLIYVCGGSLGNNVSGRVLNSCEVYDPATETWTELCPMIEARKNHGLVFVKDKIFAVGGQ
410 420 430 440 450 460
490 500 510 520 530 540
pF1KE4 NGLGGLDNVEYYDIKLNEWKMVSPMPWKGVTVKCAAVGSIVYVLAGFQGVGRLGHILEYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NGLGGLDNVEYYDIKLNEWKMVSPMPWKGVTVKCAAVGSIVYVLAGFQGVGRLGHILEYN
470 480 490 500 510 520
550 560 570 580
pF1KE4 TETDKWVANSKVRAFPVTSCLICVVDTCGANEETLET
:::::::::::::::::::::::::::::::::::::
XP_016 TETDKWVANSKVRAFPVTSCLICVVDTCGANEETLET
530 540 550 560
>>NP_061334 (OMIM: 611119,612943,617055) kelch-like prot (538 aa)
initn: 3665 init1: 3665 opt: 3665 Z-score: 3946.6 bits: 740.1 E(85289): 4.3e-213
Smith-Waterman score: 3665; 100.0% identity (100.0% similar) in 538 aa overlap (49-586:1-538)
20 30 40 50 60 70
pF1KE4 AAREEAKLLAGFMGVMNNMRKQKTLCDVILMVQERKIPAHRVVLAAASHFFNLMFTTNML
::::::::::::::::::::::::::::::
NP_061 MVQERKIPAHRVVLAAASHFFNLMFTTNML
10 20 30
80 90 100 110 120 130
pF1KE4 ESKSFEVELKDAEPDIIEQLVEFAYTARISVNSNNVQSLLDAANQYQIEPVKKMCVDFLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 ESKSFEVELKDAEPDIIEQLVEFAYTARISVNSNNVQSLLDAANQYQIEPVKKMCVDFLK
40 50 60 70 80 90
140 150 160 170 180 190
pF1KE4 EQVDASNCLGISVLAECLDCPELKATADDFIHQHFTEVYKTDEFLQLDVKRVTHLLNQDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 EQVDASNCLGISVLAECLDCPELKATADDFIHQHFTEVYKTDEFLQLDVKRVTHLLNQDT
100 110 120 130 140 150
200 210 220 230 240 250
pF1KE4 LTVRAEDQVYDAAVRWLKYDEPNRQPFMVDILAKVRFPLISKNFLSKTVQAEPLIQDNPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 LTVRAEDQVYDAAVRWLKYDEPNRQPFMVDILAKVRFPLISKNFLSKTVQAEPLIQDNPE
160 170 180 190 200 210
260 270 280 290 300 310
pF1KE4 CLKMVISGMRYHLLSPEDREELVDGTRPRRKKHDYRIALFGGSQPQSCRYFNPKDYSWTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 CLKMVISGMRYHLLSPEDREELVDGTRPRRKKHDYRIALFGGSQPQSCRYFNPKDYSWTD
220 230 240 250 260 270
320 330 340 350 360 370
pF1KE4 IRCPFEKRRDAACVFWDNVVYILGGSQLFPIKRMDCYNVVKDSWYSKLGPPTPRDSLAAC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 IRCPFEKRRDAACVFWDNVVYILGGSQLFPIKRMDCYNVVKDSWYSKLGPPTPRDSLAAC
280 290 300 310 320 330
380 390 400 410 420 430
pF1KE4 AAEGKIYTSGGSEVGNSALYLFECYDTRTESWHTKPSMLTQRCSHGMVEANGLIYVCGGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 AAEGKIYTSGGSEVGNSALYLFECYDTRTESWHTKPSMLTQRCSHGMVEANGLIYVCGGS
340 350 360 370 380 390
440 450 460 470 480 490
pF1KE4 LGNNVSGRVLNSCEVYDPATETWTELCPMIEARKNHGLVFVKDKIFAVGGQNGLGGLDNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 LGNNVSGRVLNSCEVYDPATETWTELCPMIEARKNHGLVFVKDKIFAVGGQNGLGGLDNV
400 410 420 430 440 450
500 510 520 530 540 550
pF1KE4 EYYDIKLNEWKMVSPMPWKGVTVKCAAVGSIVYVLAGFQGVGRLGHILEYNTETDKWVAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 EYYDIKLNEWKMVSPMPWKGVTVKCAAVGSIVYVLAGFQGVGRLGHILEYNTETDKWVAN
460 470 480 490 500 510
560 570 580
pF1KE4 SKVRAFPVTSCLICVVDTCGANEETLET
::::::::::::::::::::::::::::
NP_061 SKVRAFPVTSCLICVVDTCGANEETLET
520 530
>>XP_006715819 (OMIM: 611119,612943,617055) PREDICTED: k (551 aa)
initn: 3035 init1: 3035 opt: 3047 Z-score: 3281.9 bits: 617.1 E(85289): 4.6e-176
Smith-Waterman score: 3629; 97.6% identity (97.6% similar) in 551 aa overlap (49-586:1-551)
20 30 40 50 60 70
pF1KE4 AAREEAKLLAGFMGVMNNMRKQKTLCDVILMVQERKIPAHRVVLAAASHFFNLMFTTNML
::::::::::::::::::::::::::::::
XP_006 MVQERKIPAHRVVLAAASHFFNLMFTTNML
10 20 30
80 90 100 110 120 130
pF1KE4 ESKSFEVELKDAEPDIIEQLVEFAYTARISVNSNNVQSLLDAANQYQIEPVKKMCVDFLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ESKSFEVELKDAEPDIIEQLVEFAYTARISVNSNNVQSLLDAANQYQIEPVKKMCVDFLK
40 50 60 70 80 90
140 150 160 170 180
pF1KE4 EQVDASNCLG-------------ISVLAECLDCPELKATADDFIHQHFTEVYKTDEFLQL
:::::::::: :::::::::::::::::::::::::::::::::::::
XP_006 EQVDASNCLGEAEKVDQSLPECGISVLAECLDCPELKATADDFIHQHFTEVYKTDEFLQL
100 110 120 130 140 150
190 200 210 220 230 240
pF1KE4 DVKRVTHLLNQDTLTVRAEDQVYDAAVRWLKYDEPNRQPFMVDILAKVRFPLISKNFLSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DVKRVTHLLNQDTLTVRAEDQVYDAAVRWLKYDEPNRQPFMVDILAKVRFPLISKNFLSK
160 170 180 190 200 210
250 260 270 280 290 300
pF1KE4 TVQAEPLIQDNPECLKMVISGMRYHLLSPEDREELVDGTRPRRKKHDYRIALFGGSQPQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TVQAEPLIQDNPECLKMVISGMRYHLLSPEDREELVDGTRPRRKKHDYRIALFGGSQPQS
220 230 240 250 260 270
310 320 330 340 350 360
pF1KE4 CRYFNPKDYSWTDIRCPFEKRRDAACVFWDNVVYILGGSQLFPIKRMDCYNVVKDSWYSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 CRYFNPKDYSWTDIRCPFEKRRDAACVFWDNVVYILGGSQLFPIKRMDCYNVVKDSWYSK
280 290 300 310 320 330
370 380 390 400 410 420
pF1KE4 LGPPTPRDSLAACAAEGKIYTSGGSEVGNSALYLFECYDTRTESWHTKPSMLTQRCSHGM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LGPPTPRDSLAACAAEGKIYTSGGSEVGNSALYLFECYDTRTESWHTKPSMLTQRCSHGM
340 350 360 370 380 390
430 440 450 460 470 480
pF1KE4 VEANGLIYVCGGSLGNNVSGRVLNSCEVYDPATETWTELCPMIEARKNHGLVFVKDKIFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VEANGLIYVCGGSLGNNVSGRVLNSCEVYDPATETWTELCPMIEARKNHGLVFVKDKIFA
400 410 420 430 440 450
490 500 510 520 530 540
pF1KE4 VGGQNGLGGLDNVEYYDIKLNEWKMVSPMPWKGVTVKCAAVGSIVYVLAGFQGVGRLGHI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VGGQNGLGGLDNVEYYDIKLNEWKMVSPMPWKGVTVKCAAVGSIVYVLAGFQGVGRLGHI
460 470 480 490 500 510
550 560 570 580
pF1KE4 LEYNTETDKWVANSKVRAFPVTSCLICVVDTCGANEETLET
:::::::::::::::::::::::::::::::::::::::::
XP_006 LEYNTETDKWVANSKVRAFPVTSCLICVVDTCGANEETLET
520 530 540 550
>>XP_006715817 (OMIM: 611119,612943,617055) PREDICTED: k (577 aa)
initn: 3035 init1: 3035 opt: 3047 Z-score: 3281.6 bits: 617.2 E(85289): 4.7e-176
Smith-Waterman score: 3683; 97.5% identity (97.7% similar) in 560 aa overlap (40-586:18-577)
10 20 30 40 50 60
pF1KE4 SKKKTEKKLAAREEAKLLAGFMGVMNNMRKQKTLCDVILMVQERKIPAHRVVLAAASHFF
.:::::::::::::::::::::::::::::
XP_006 MLGGTDCRTFLTSHINLKKTLCDVILMVQERKIPAHRVVLAAASHFF
10 20 30 40
70 80 90 100 110 120
pF1KE4 NLMFTTNMLESKSFEVELKDAEPDIIEQLVEFAYTARISVNSNNVQSLLDAANQYQIEPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NLMFTTNMLESKSFEVELKDAEPDIIEQLVEFAYTARISVNSNNVQSLLDAANQYQIEPV
50 60 70 80 90 100
130 140 150 160 170
pF1KE4 KKMCVDFLKEQVDASNCLG-------------ISVLAECLDCPELKATADDFIHQHFTEV
::::::::::::::::::: ::::::::::::::::::::::::::::
XP_006 KKMCVDFLKEQVDASNCLGEAEKVDQSLPECGISVLAECLDCPELKATADDFIHQHFTEV
110 120 130 140 150 160
180 190 200 210 220 230
pF1KE4 YKTDEFLQLDVKRVTHLLNQDTLTVRAEDQVYDAAVRWLKYDEPNRQPFMVDILAKVRFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YKTDEFLQLDVKRVTHLLNQDTLTVRAEDQVYDAAVRWLKYDEPNRQPFMVDILAKVRFP
170 180 190 200 210 220
240 250 260 270 280 290
pF1KE4 LISKNFLSKTVQAEPLIQDNPECLKMVISGMRYHLLSPEDREELVDGTRPRRKKHDYRIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LISKNFLSKTVQAEPLIQDNPECLKMVISGMRYHLLSPEDREELVDGTRPRRKKHDYRIA
230 240 250 260 270 280
300 310 320 330 340 350
pF1KE4 LFGGSQPQSCRYFNPKDYSWTDIRCPFEKRRDAACVFWDNVVYILGGSQLFPIKRMDCYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LFGGSQPQSCRYFNPKDYSWTDIRCPFEKRRDAACVFWDNVVYILGGSQLFPIKRMDCYN
290 300 310 320 330 340
360 370 380 390 400 410
pF1KE4 VVKDSWYSKLGPPTPRDSLAACAAEGKIYTSGGSEVGNSALYLFECYDTRTESWHTKPSM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VVKDSWYSKLGPPTPRDSLAACAAEGKIYTSGGSEVGNSALYLFECYDTRTESWHTKPSM
350 360 370 380 390 400
420 430 440 450 460 470
pF1KE4 LTQRCSHGMVEANGLIYVCGGSLGNNVSGRVLNSCEVYDPATETWTELCPMIEARKNHGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LTQRCSHGMVEANGLIYVCGGSLGNNVSGRVLNSCEVYDPATETWTELCPMIEARKNHGL
410 420 430 440 450 460
480 490 500 510 520 530
pF1KE4 VFVKDKIFAVGGQNGLGGLDNVEYYDIKLNEWKMVSPMPWKGVTVKCAAVGSIVYVLAGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VFVKDKIFAVGGQNGLGGLDNVEYYDIKLNEWKMVSPMPWKGVTVKCAAVGSIVYVLAGF
470 480 490 500 510 520
540 550 560 570 580
pF1KE4 QGVGRLGHILEYNTETDKWVANSKVRAFPVTSCLICVVDTCGANEETLET
::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QGVGRLGHILEYNTETDKWVANSKVRAFPVTSCLICVVDTCGANEETLET
530 540 550 560 570
>>XP_006715818 (OMIM: 611119,612943,617055) PREDICTED: k (577 aa)
initn: 3035 init1: 3035 opt: 3047 Z-score: 3281.6 bits: 617.2 E(85289): 4.7e-176
Smith-Waterman score: 3683; 97.5% identity (97.7% similar) in 560 aa overlap (40-586:18-577)
10 20 30 40 50 60
pF1KE4 SKKKTEKKLAAREEAKLLAGFMGVMNNMRKQKTLCDVILMVQERKIPAHRVVLAAASHFF
.:::::::::::::::::::::::::::::
XP_006 MLGGTDCRTFLTSHINLKKTLCDVILMVQERKIPAHRVVLAAASHFF
10 20 30 40
70 80 90 100 110 120
pF1KE4 NLMFTTNMLESKSFEVELKDAEPDIIEQLVEFAYTARISVNSNNVQSLLDAANQYQIEPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NLMFTTNMLESKSFEVELKDAEPDIIEQLVEFAYTARISVNSNNVQSLLDAANQYQIEPV
50 60 70 80 90 100
130 140 150 160 170
pF1KE4 KKMCVDFLKEQVDASNCLG-------------ISVLAECLDCPELKATADDFIHQHFTEV
::::::::::::::::::: ::::::::::::::::::::::::::::
XP_006 KKMCVDFLKEQVDASNCLGEAEKVDQSLPECGISVLAECLDCPELKATADDFIHQHFTEV
110 120 130 140 150 160
180 190 200 210 220 230
pF1KE4 YKTDEFLQLDVKRVTHLLNQDTLTVRAEDQVYDAAVRWLKYDEPNRQPFMVDILAKVRFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YKTDEFLQLDVKRVTHLLNQDTLTVRAEDQVYDAAVRWLKYDEPNRQPFMVDILAKVRFP
170 180 190 200 210 220
240 250 260 270 280 290
pF1KE4 LISKNFLSKTVQAEPLIQDNPECLKMVISGMRYHLLSPEDREELVDGTRPRRKKHDYRIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LISKNFLSKTVQAEPLIQDNPECLKMVISGMRYHLLSPEDREELVDGTRPRRKKHDYRIA
230 240 250 260 270 280
300 310 320 330 340 350
pF1KE4 LFGGSQPQSCRYFNPKDYSWTDIRCPFEKRRDAACVFWDNVVYILGGSQLFPIKRMDCYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LFGGSQPQSCRYFNPKDYSWTDIRCPFEKRRDAACVFWDNVVYILGGSQLFPIKRMDCYN
290 300 310 320 330 340
360 370 380 390 400 410
pF1KE4 VVKDSWYSKLGPPTPRDSLAACAAEGKIYTSGGSEVGNSALYLFECYDTRTESWHTKPSM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VVKDSWYSKLGPPTPRDSLAACAAEGKIYTSGGSEVGNSALYLFECYDTRTESWHTKPSM
350 360 370 380 390 400
420 430 440 450 460 470
pF1KE4 LTQRCSHGMVEANGLIYVCGGSLGNNVSGRVLNSCEVYDPATETWTELCPMIEARKNHGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LTQRCSHGMVEANGLIYVCGGSLGNNVSGRVLNSCEVYDPATETWTELCPMIEARKNHGL
410 420 430 440 450 460
480 490 500 510 520 530
pF1KE4 VFVKDKIFAVGGQNGLGGLDNVEYYDIKLNEWKMVSPMPWKGVTVKCAAVGSIVYVLAGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VFVKDKIFAVGGQNGLGGLDNVEYYDIKLNEWKMVSPMPWKGVTVKCAAVGSIVYVLAGF
470 480 490 500 510 520
540 550 560 570 580
pF1KE4 QGVGRLGHILEYNTETDKWVANSKVRAFPVTSCLICVVDTCGANEETLET
::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QGVGRLGHILEYNTETDKWVANSKVRAFPVTSCLICVVDTCGANEETLET
530 540 550 560 570
>>XP_006715816 (OMIM: 611119,612943,617055) PREDICTED: k (599 aa)
initn: 3035 init1: 3035 opt: 3047 Z-score: 3281.4 bits: 617.2 E(85289): 4.9e-176
Smith-Waterman score: 3923; 97.8% identity (97.8% similar) in 599 aa overlap (1-586:1-599)
10 20 30 40 50 60
pF1KE4 MAASGVEKSSKKKTEKKLAAREEAKLLAGFMGVMNNMRKQKTLCDVILMVQERKIPAHRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MAASGVEKSSKKKTEKKLAAREEAKLLAGFMGVMNNMRKQKTLCDVILMVQERKIPAHRV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 VLAAASHFFNLMFTTNMLESKSFEVELKDAEPDIIEQLVEFAYTARISVNSNNVQSLLDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VLAAASHFFNLMFTTNMLESKSFEVELKDAEPDIIEQLVEFAYTARISVNSNNVQSLLDA
70 80 90 100 110 120
130 140 150 160
pF1KE4 ANQYQIEPVKKMCVDFLKEQVDASNCLG-------------ISVLAECLDCPELKATADD
:::::::::::::::::::::::::::: :::::::::::::::::::
XP_006 ANQYQIEPVKKMCVDFLKEQVDASNCLGEAEKVDQSLPECGISVLAECLDCPELKATADD
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE4 FIHQHFTEVYKTDEFLQLDVKRVTHLLNQDTLTVRAEDQVYDAAVRWLKYDEPNRQPFMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FIHQHFTEVYKTDEFLQLDVKRVTHLLNQDTLTVRAEDQVYDAAVRWLKYDEPNRQPFMV
190 200 210 220 230 240
230 240 250 260 270 280
pF1KE4 DILAKVRFPLISKNFLSKTVQAEPLIQDNPECLKMVISGMRYHLLSPEDREELVDGTRPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DILAKVRFPLISKNFLSKTVQAEPLIQDNPECLKMVISGMRYHLLSPEDREELVDGTRPR
250 260 270 280 290 300
290 300 310 320 330 340
pF1KE4 RKKHDYRIALFGGSQPQSCRYFNPKDYSWTDIRCPFEKRRDAACVFWDNVVYILGGSQLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RKKHDYRIALFGGSQPQSCRYFNPKDYSWTDIRCPFEKRRDAACVFWDNVVYILGGSQLF
310 320 330 340 350 360
350 360 370 380 390 400
pF1KE4 PIKRMDCYNVVKDSWYSKLGPPTPRDSLAACAAEGKIYTSGGSEVGNSALYLFECYDTRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PIKRMDCYNVVKDSWYSKLGPPTPRDSLAACAAEGKIYTSGGSEVGNSALYLFECYDTRT
370 380 390 400 410 420
410 420 430 440 450 460
pF1KE4 ESWHTKPSMLTQRCSHGMVEANGLIYVCGGSLGNNVSGRVLNSCEVYDPATETWTELCPM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ESWHTKPSMLTQRCSHGMVEANGLIYVCGGSLGNNVSGRVLNSCEVYDPATETWTELCPM
430 440 450 460 470 480
470 480 490 500 510 520
pF1KE4 IEARKNHGLVFVKDKIFAVGGQNGLGGLDNVEYYDIKLNEWKMVSPMPWKGVTVKCAAVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IEARKNHGLVFVKDKIFAVGGQNGLGGLDNVEYYDIKLNEWKMVSPMPWKGVTVKCAAVG
490 500 510 520 530 540
530 540 550 560 570 580
pF1KE4 SIVYVLAGFQGVGRLGHILEYNTETDKWVANSKVRAFPVTSCLICVVDTCGANEETLET
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SIVYVLAGFQGVGRLGHILEYNTETDKWVANSKVRAFPVTSCLICVVDTCGANEETLET
550 560 570 580 590
>>XP_016867929 (OMIM: 611119,612943,617055) PREDICTED: k (325 aa)
initn: 2045 init1: 2045 opt: 2045 Z-score: 2207.2 bits: 417.5 E(85289): 3.3e-116
Smith-Waterman score: 2045; 100.0% identity (100.0% similar) in 312 aa overlap (1-312:1-312)
10 20 30 40 50 60
pF1KE4 MAASGVEKSSKKKTEKKLAAREEAKLLAGFMGVMNNMRKQKTLCDVILMVQERKIPAHRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAASGVEKSSKKKTEKKLAAREEAKLLAGFMGVMNNMRKQKTLCDVILMVQERKIPAHRV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 VLAAASHFFNLMFTTNMLESKSFEVELKDAEPDIIEQLVEFAYTARISVNSNNVQSLLDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLAAASHFFNLMFTTNMLESKSFEVELKDAEPDIIEQLVEFAYTARISVNSNNVQSLLDA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 ANQYQIEPVKKMCVDFLKEQVDASNCLGISVLAECLDCPELKATADDFIHQHFTEVYKTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ANQYQIEPVKKMCVDFLKEQVDASNCLGISVLAECLDCPELKATADDFIHQHFTEVYKTD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 EFLQLDVKRVTHLLNQDTLTVRAEDQVYDAAVRWLKYDEPNRQPFMVDILAKVRFPLISK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EFLQLDVKRVTHLLNQDTLTVRAEDQVYDAAVRWLKYDEPNRQPFMVDILAKVRFPLISK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 NFLSKTVQAEPLIQDNPECLKMVISGMRYHLLSPEDREELVDGTRPRRKKHDYRIALFGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NFLSKTVQAEPLIQDNPECLKMVISGMRYHLLSPEDREELVDGTRPRRKKHDYRIALFGG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 SQPQSCRYFNPKDYSWTDIRCPFEKRRDAACVFWDNVVYILGGSQLFPIKRMDCYNVVKD
::::::::::::
XP_016 SQPQSCRYFNPKLKRDAYSSTRAWK
310 320
>>XP_016867930 (OMIM: 611119,612943,617055) PREDICTED: k (303 aa)
initn: 1805 init1: 1805 opt: 1805 Z-score: 1949.5 bits: 369.7 E(85289): 7.5e-102
Smith-Waterman score: 1805; 99.6% identity (100.0% similar) in 273 aa overlap (40-312:18-290)
10 20 30 40 50 60
pF1KE4 SKKKTEKKLAAREEAKLLAGFMGVMNNMRKQKTLCDVILMVQERKIPAHRVVLAAASHFF
.:::::::::::::::::::::::::::::
XP_016 MLGGTDCRTFLTSHINLKKTLCDVILMVQERKIPAHRVVLAAASHFF
10 20 30 40
70 80 90 100 110 120
pF1KE4 NLMFTTNMLESKSFEVELKDAEPDIIEQLVEFAYTARISVNSNNVQSLLDAANQYQIEPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NLMFTTNMLESKSFEVELKDAEPDIIEQLVEFAYTARISVNSNNVQSLLDAANQYQIEPV
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE4 KKMCVDFLKEQVDASNCLGISVLAECLDCPELKATADDFIHQHFTEVYKTDEFLQLDVKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKMCVDFLKEQVDASNCLGISVLAECLDCPELKATADDFIHQHFTEVYKTDEFLQLDVKR
110 120 130 140 150 160
190 200 210 220 230 240
pF1KE4 VTHLLNQDTLTVRAEDQVYDAAVRWLKYDEPNRQPFMVDILAKVRFPLISKNFLSKTVQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VTHLLNQDTLTVRAEDQVYDAAVRWLKYDEPNRQPFMVDILAKVRFPLISKNFLSKTVQA
170 180 190 200 210 220
250 260 270 280 290 300
pF1KE4 EPLIQDNPECLKMVISGMRYHLLSPEDREELVDGTRPRRKKHDYRIALFGGSQPQSCRYF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EPLIQDNPECLKMVISGMRYHLLSPEDREELVDGTRPRRKKHDYRIALFGGSQPQSCRYF
230 240 250 260 270 280
310 320 330 340 350 360
pF1KE4 NPKDYSWTDIRCPFEKRRDAACVFWDNVVYILGGSQLFPIKRMDCYNVVKDSWYSKLGPP
:::
XP_016 NPKLKRDAYSSTRAWK
290 300
>>XP_006715820 (OMIM: 611119,612943,617055) PREDICTED: k (338 aa)
initn: 1121 init1: 1121 opt: 1133 Z-score: 1226.3 bits: 236.1 E(85289): 1.4e-61
Smith-Waterman score: 2009; 96.0% identity (96.0% similar) in 325 aa overlap (1-312:1-325)
10 20 30 40 50 60
pF1KE4 MAASGVEKSSKKKTEKKLAAREEAKLLAGFMGVMNNMRKQKTLCDVILMVQERKIPAHRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MAASGVEKSSKKKTEKKLAAREEAKLLAGFMGVMNNMRKQKTLCDVILMVQERKIPAHRV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 VLAAASHFFNLMFTTNMLESKSFEVELKDAEPDIIEQLVEFAYTARISVNSNNVQSLLDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VLAAASHFFNLMFTTNMLESKSFEVELKDAEPDIIEQLVEFAYTARISVNSNNVQSLLDA
70 80 90 100 110 120
130 140 150 160
pF1KE4 ANQYQIEPVKKMCVDFLKEQVDASNCLG-------------ISVLAECLDCPELKATADD
:::::::::::::::::::::::::::: :::::::::::::::::::
XP_006 ANQYQIEPVKKMCVDFLKEQVDASNCLGEAEKVDQSLPECGISVLAECLDCPELKATADD
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE4 FIHQHFTEVYKTDEFLQLDVKRVTHLLNQDTLTVRAEDQVYDAAVRWLKYDEPNRQPFMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FIHQHFTEVYKTDEFLQLDVKRVTHLLNQDTLTVRAEDQVYDAAVRWLKYDEPNRQPFMV
190 200 210 220 230 240
230 240 250 260 270 280
pF1KE4 DILAKVRFPLISKNFLSKTVQAEPLIQDNPECLKMVISGMRYHLLSPEDREELVDGTRPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DILAKVRFPLISKNFLSKTVQAEPLIQDNPECLKMVISGMRYHLLSPEDREELVDGTRPR
250 260 270 280 290 300
290 300 310 320 330 340
pF1KE4 RKKHDYRIALFGGSQPQSCRYFNPKDYSWTDIRCPFEKRRDAACVFWDNVVYILGGSQLF
:::::::::::::::::::::::::
XP_006 RKKHDYRIALFGGSQPQSCRYFNPKLKRDAYSSTRAWK
310 320 330
586 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 17:27:26 2016 done: Mon Nov 7 17:27:28 2016
Total Scan time: 9.790 Total Display time: 0.130
Function used was FASTA [36.3.4 Apr, 2011]