Result of FASTA (omim) for
pFN21AE4123
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE4123, 511 aa
1>>>pF1KE4123 511 - 511 aa - 511 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.7971+/-0.000432; mu= 15.9166+/- 0.027
mean_var=108.4258+/-22.188, 0's: 0 Z-trim(113.4): 192 B-trim: 186 in 1/50
Lambda= 0.123171
statistics sampled from 22357 (22764) to 22357 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.627), E-opt: 0.2 (0.267), width: 16
Scan time: 9.640
The best scores are: opt bits E(85289)
NP_005540 (OMIM: 602420) potassium voltage-gated c ( 511) 3377 611.6 1.8e-174
NP_000208 (OMIM: 160120,176260) potassium voltage- ( 495) 1951 358.2 3.3e-98
XP_011539702 (OMIM: 176262,616366) PREDICTED: pota ( 499) 1940 356.2 1.3e-97
XP_011539699 (OMIM: 176262,616366) PREDICTED: pota ( 499) 1940 356.2 1.3e-97
XP_016856702 (OMIM: 176262,616366) PREDICTED: pota ( 499) 1940 356.2 1.3e-97
XP_011539701 (OMIM: 176262,616366) PREDICTED: pota ( 499) 1940 356.2 1.3e-97
XP_011539700 (OMIM: 176262,616366) PREDICTED: pota ( 499) 1940 356.2 1.3e-97
XP_011539698 (OMIM: 176262,616366) PREDICTED: pota ( 499) 1940 356.2 1.3e-97
NP_004965 (OMIM: 176262,616366) potassium voltage- ( 499) 1940 356.2 1.3e-97
NP_002223 (OMIM: 176263) potassium voltage-gated c ( 575) 1927 354.0 7.1e-97
NP_001191198 (OMIM: 176262,616366) potassium volta ( 356) 1189 222.6 1.5e-57
NP_002224 (OMIM: 176266) potassium voltage-gated c ( 653) 1120 210.6 1.1e-53
NP_114092 (OMIM: 176268) potassium voltage-gated c ( 456) 1081 203.5 1.1e-51
NP_002225 (OMIM: 176267,612240) potassium voltage- ( 613) 838 160.5 1.3e-38
XP_016874760 (OMIM: 176257) PREDICTED: potassium v ( 529) 824 157.9 6.7e-38
XP_016874761 (OMIM: 176257) PREDICTED: potassium v ( 529) 824 157.9 6.7e-38
XP_011519257 (OMIM: 176257) PREDICTED: potassium v ( 529) 824 157.9 6.7e-38
XP_016874759 (OMIM: 176257) PREDICTED: potassium v ( 529) 824 157.9 6.7e-38
XP_005253743 (OMIM: 176257) PREDICTED: potassium v ( 529) 824 157.9 6.7e-38
NP_002226 (OMIM: 176257) potassium voltage-gated c ( 529) 824 157.9 6.7e-38
XP_011527101 (OMIM: 600397,616056) PREDICTED: pota ( 858) 738 142.8 3.8e-33
XP_006723847 (OMIM: 600397,616056) PREDICTED: pota ( 858) 738 142.8 3.8e-33
NP_004966 (OMIM: 600397,616056) potassium voltage- ( 858) 738 142.8 3.8e-33
NP_004761 (OMIM: 607738) potassium voltage-gated c ( 911) 737 142.7 4.4e-33
NP_001309728 (OMIM: 602905) potassium voltage-gate ( 526) 687 133.6 1.4e-30
NP_002242 (OMIM: 602905) potassium voltage-gated c ( 526) 687 133.6 1.4e-30
XP_016883335 (OMIM: 602905) PREDICTED: potassium v ( 527) 687 133.6 1.4e-30
XP_011542212 (OMIM: 300281) PREDICTED: potassium v ( 647) 676 131.7 6.4e-30
NP_004970 (OMIM: 300281) potassium voltage-gated c ( 647) 676 131.7 6.4e-30
NP_715624 (OMIM: 176256) potassium voltage-gated c ( 558) 662 129.2 3.2e-29
XP_005268912 (OMIM: 176256) PREDICTED: potassium v ( 574) 662 129.2 3.3e-29
NP_001247428 (OMIM: 176256) potassium voltage-gate ( 583) 662 129.2 3.3e-29
XP_006719446 (OMIM: 176256) PREDICTED: potassium v ( 612) 662 129.2 3.4e-29
XP_016874771 (OMIM: 176256) PREDICTED: potassium v ( 612) 662 129.2 3.4e-29
XP_006719448 (OMIM: 176256) PREDICTED: potassium v ( 612) 662 129.2 3.4e-29
XP_006719447 (OMIM: 176256) PREDICTED: potassium v ( 612) 662 129.2 3.4e-29
XP_006719445 (OMIM: 176256) PREDICTED: potassium v ( 613) 662 129.2 3.4e-29
NP_631874 (OMIM: 176256) potassium voltage-gated c ( 613) 662 129.2 3.4e-29
NP_001247426 (OMIM: 176256) potassium voltage-gate ( 618) 662 129.2 3.5e-29
NP_001247427 (OMIM: 176256) potassium voltage-gate ( 629) 662 129.2 3.5e-29
NP_631875 (OMIM: 176256) potassium voltage-gated c ( 638) 662 129.2 3.5e-29
XP_016869470 (OMIM: 607738) PREDICTED: potassium v ( 666) 659 128.7 5.3e-29
XP_016869471 (OMIM: 607738) PREDICTED: potassium v ( 666) 659 128.7 5.3e-29
XP_006710694 (OMIM: 605411,607346,616399) PREDICTE ( 510) 654 127.7 8.1e-29
XP_006710693 (OMIM: 605411,607346,616399) PREDICTE ( 636) 654 127.8 9.5e-29
NP_751948 (OMIM: 605411,607346,616399) potassium v ( 636) 654 127.8 9.5e-29
XP_006710692 (OMIM: 605411,607346,616399) PREDICTE ( 655) 654 127.8 9.7e-29
XP_016856733 (OMIM: 605411,607346,616399) PREDICTE ( 655) 654 127.8 9.7e-29
NP_004971 (OMIM: 605411,607346,616399) potassium v ( 655) 654 127.8 9.7e-29
XP_005270908 (OMIM: 605411,607346,616399) PREDICTE ( 655) 654 127.8 9.7e-29
>>NP_005540 (OMIM: 602420) potassium voltage-gated chann (511 aa)
initn: 3377 init1: 3377 opt: 3377 Z-score: 3253.4 bits: 611.6 E(85289): 1.8e-174
Smith-Waterman score: 3377; 100.0% identity (100.0% similar) in 511 aa overlap (1-511:1-511)
10 20 30 40 50 60
pF1KE4 MDVCGWKEMEVALVNFDNSDEIQEEPGYATDFDSTSPKGRPGGSSFSNGKILISESTNHE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MDVCGWKEMEVALVNFDNSDEIQEEPGYATDFDSTSPKGRPGGSSFSNGKILISESTNHE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 TAFSKLPGDYADPPGPEPVVLNEGNQRVIINIAGLRFETQLRTLSQFPETLLGDREKRMQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 TAFSKLPGDYADPPGPEPVVLNEGNQRVIINIAGLRFETQLRTLSQFPETLLGDREKRMQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 FFDSMRNEYFFDRNRPSFDGILYYYQSGGKIRRPANVPIDIFADEISFYELGSEAMDQFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 FFDSMRNEYFFDRNRPSFDGILYYYQSGGKIRRPANVPIDIFADEISFYELGSEAMDQFR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 EDEGFIKDPETLLPTNDIHRQFWLLFEYPESSSAARAVAVVSVLVVVISITIFCLETLPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 EDEGFIKDPETLLPTNDIHRQFWLLFEYPESSSAARAVAVVSVLVVVISITIFCLETLPE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 FREDRELKVVRDPNLNMSKTVLSQTMFTDPFFMVESTCIVWFTFELVLRFVVCPSKTDFF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 FREDRELKVVRDPNLNMSKTVLSQTMFTDPFFMVESTCIVWFTFELVLRFVVCPSKTDFF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 RNIMNIIDIISIIPYFATLITELVQETEPSAQQNMSLAILRIIRLVRVFRIFKLSRHSKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 RNIMNIIDIISIIPYFATLITELVQETEPSAQQNMSLAILRIIRLVRVFRIFKLSRHSKG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 LQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEVDEPESHFSSIPDGFWWAVVTMT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 LQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEVDEPESHFSSIPDGFWWAVVTMT
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE4 TVGYGDMCPTTPGGKIVGTLCAIAGVLTIALPVPVIVSNFNYFYHRETENEEKQNIPGEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 TVGYGDMCPTTPGGKIVGTLCAIAGVLTIALPVPVIVSNFNYFYHRETENEEKQNIPGEI
430 440 450 460 470 480
490 500 510
pF1KE4 ERILNSVGSRMGSTDSLNKTNGGCSTEKSRK
:::::::::::::::::::::::::::::::
NP_005 ERILNSVGSRMGSTDSLNKTNGGCSTEKSRK
490 500 510
>>NP_000208 (OMIM: 160120,176260) potassium voltage-gate (495 aa)
initn: 1945 init1: 1592 opt: 1951 Z-score: 1884.1 bits: 358.2 E(85289): 3.3e-98
Smith-Waterman score: 1951; 69.5% identity (88.7% similar) in 416 aa overlap (64-476:13-427)
40 50 60 70 80 90
pF1KE4 STSPKGRPGGSSFSNGKILISESTNHETAFSKLPGDYADPPGPEPVVLN--EGNQRVIIN
: :: : :. . . : .::.::
NP_000 MTVMSGENVDEASAAPGHPQDGSYPRQADHDDHECCERVVIN
10 20 30 40
100 110 120 130 140 150
pF1KE4 IAGLRFETQLRTLSQFPETLLGDREKRMQFFDSMRNEYFFDRNRPSFDGILYYYQSGGKI
:.::::::::.::.:::.::::. .:::..:: .::::::::::::::.:::::::::..
NP_000 ISGLRFETQLKTLAQFPNTLLGNPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRL
50 60 70 80 90 100
160 170 180 190 200 210
pF1KE4 RRPANVPIDIFADEISFYELGSEAMDQFREDEGFIKDPETLLPTNDIHRQFWLLFEYPES
:::.:::.:.:..::.::::: :::..:::::::::. : :: .. .:: :::::::::
NP_000 RRPVNVPLDMFSEEIKFYELGEEAMEKFREDEGFIKEEERPLPEKEYQRQVWLLFEYPES
110 120 130 140 150 160
220 230 240 250 260 270
pF1KE4 SSAARAVAVVSVLVVVISITIFCLETLPEFREDRELKVVRDPNLNMSKTVLSQTMFTDPF
:. ::..:.:::.:..:::.:::::::::...:... . .. . .. ....:::::
NP_000 SGPARVIAIVSVMVILISIVIFCLETLPELKDDKDFTGTVH-RIDNTTVIYNSNIFTDPF
170 180 190 200 210 220
280 290 300 310 320 330
pF1KE4 FMVESTCIVWFTFELVLRFVVCPSKTDFFRNIMNIIDIISIIPYFATLITELV-QETEPS
:.::. ::.::.::::.:: .::::::::.::::.:::..::::: :: ::.. :: . .
NP_000 FIVETLCIIWFSFELVVRFFACPSKTDFFKNIMNFIDIVAIIPYFITLGTEIAEQEGNQK
230 240 250 260 270 280
340 350 360 370 380 390
pF1KE4 AQQNMSLAILRIIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFS
..: ::::::.::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 GEQATSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFS
290 300 310 320 330 340
400 410 420 430 440 450
pF1KE4 SAVYFAEVDEPESHFSSIPDGFWWAVVTMTTVGYGDMCPTTPGGKIVGTLCAIAGVLTIA
:::::::..: :::::::::.::::::.::::::::: :.: ::::::.:::::::::::
NP_000 SAVYFAEAEEAESHFSSIPDAFWWAVVSMTTVGYGDMYPVTIGGKIVGSLCAIAGVLTIA
350 360 370 380 390 400
460 470 480 490 500 510
pF1KE4 LPVPVIVSNFNYFYHRETENEEKQNIPGEIERILNSVGSRMGSTDSLNKTNGGCSTEKSR
:::::::::::::::::::.::. ..
NP_000 LPVPVIVSNFNYFYHRETEGEEQAQLLHVSSPNLASDSDLSRRSSSTMSKSEYMEIEEDM
410 420 430 440 450 460
>>XP_011539702 (OMIM: 176262,616366) PREDICTED: potassiu (499 aa)
initn: 1943 init1: 835 opt: 1940 Z-score: 1873.5 bits: 356.2 E(85289): 1.3e-97
Smith-Waterman score: 1940; 66.7% identity (83.1% similar) in 450 aa overlap (66-509:15-456)
40 50 60 70 80 90
pF1KE4 SPKGRPGGSSFSNGKILISESTNHETAFSKLPGDYADPPGPEPVVLNEGNQRVIINIAGL
::: : :: . .: .::.:::.::
XP_011 MTVATGDPADEAAALPGHPQDTYDPE--ADHECCERVVINISGL
10 20 30 40
100 110 120 130 140 150
pF1KE4 RFETQLRTLSQFPETLLGDREKRMQFFDSMRNEYFFDRNRPSFDGILYYYQSGGKIRRPA
::::::.::.::::::::: .:::..:: .::::::::::::::.:::::::::..:::.
XP_011 RFETQLKTLAQFPETLLGDPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPV
50 60 70 80 90 100
160 170 180 190 200 210
pF1KE4 NVPIDIFADEISFYELGSEAMDQFREDEGFIKDPETLLPTNDIHRQFWLLFEYPESSSAA
:::.:::..:: ::::: :::..::::::.::. : :: :...:: ::::::::::. :
XP_011 NVPLDIFSEEIRFYELGEEAMEMFREDEGYIKEEERPLPENEFQRQVWLLFEYPESSGPA
110 120 130 140 150 160
220 230 240 250 260 270
pF1KE4 RAVAVVSVLVVVISITIFCLETLPEFREDRE----LKVVRDPNLNMSKTVLSQTMFTDPF
: .:.:::.:..:::. ::::::: ::.. : :. : . ..: :::::
XP_011 RIIAIVSVMVILISIVSFCLETLPIFRDENEDMHGSGVTFHTYSNSTIGYQQSTSFTDPF
170 180 190 200 210 220
280 290 300 310 320 330
pF1KE4 FMVESTCIVWFTFELVLRFVVCPSKTDFFRNIMNIIDIISIIPYFATLITELVQETEPS-
:.::. ::.::.::...:: .::::. :: ::::::::..::::: :: :::... : .
XP_011 FIVETLCIIWFSFEFLVRFFACPSKAGFFTNIMNIIDIVAIIPYFITLGTELAEKPEDAQ
230 240 250 260 270 280
340 350 360 370 380
pF1KE4 -AQQNMSLAILRIIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILF
.:: :::::::.:::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILF
290 300 310 320 330 340
390 400 410 420 430 440
pF1KE4 SSAVYFAEVDEPESHFSSIPDGFWWAVVTMTTVGYGDMCPTTPGGKIVGTLCAIAGVLTI
::::::::.:: ::.: ::::.::::::.::::::::: ::: ::::::.::::::::::
XP_011 SSAVYFAEADERESQFPSIPDAFWWAVVSMTTVGYGDMVPTTIGGKIVGSLCAIAGVLTI
350 360 370 380 390 400
450 460 470 480 490 500
pF1KE4 ALPVPVIVSNFNYFYHRETENEEKQNIPGEIERILNSVGSRMGSTDSLNKTNGGCSTEKS
::::::::::::::::::::.::. . . . .. :. .:.:. .. . ::
XP_011 ALPVPVIVSNFNYFYHRETEGEEQA------QYLQVTSCPKIPSSPDLKKSRSASTISKS
410 420 430 440 450
510
pF1KE4 RK
XP_011 DYMEIQEGVNNSNEDFREENLKTANCTLANTNYVNITKMLTDV
460 470 480 490
>>XP_011539699 (OMIM: 176262,616366) PREDICTED: potassiu (499 aa)
initn: 1943 init1: 835 opt: 1940 Z-score: 1873.5 bits: 356.2 E(85289): 1.3e-97
Smith-Waterman score: 1940; 66.7% identity (83.1% similar) in 450 aa overlap (66-509:15-456)
40 50 60 70 80 90
pF1KE4 SPKGRPGGSSFSNGKILISESTNHETAFSKLPGDYADPPGPEPVVLNEGNQRVIINIAGL
::: : :: . .: .::.:::.::
XP_011 MTVATGDPADEAAALPGHPQDTYDPE--ADHECCERVVINISGL
10 20 30 40
100 110 120 130 140 150
pF1KE4 RFETQLRTLSQFPETLLGDREKRMQFFDSMRNEYFFDRNRPSFDGILYYYQSGGKIRRPA
::::::.::.::::::::: .:::..:: .::::::::::::::.:::::::::..:::.
XP_011 RFETQLKTLAQFPETLLGDPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPV
50 60 70 80 90 100
160 170 180 190 200 210
pF1KE4 NVPIDIFADEISFYELGSEAMDQFREDEGFIKDPETLLPTNDIHRQFWLLFEYPESSSAA
:::.:::..:: ::::: :::..::::::.::. : :: :...:: ::::::::::. :
XP_011 NVPLDIFSEEIRFYELGEEAMEMFREDEGYIKEEERPLPENEFQRQVWLLFEYPESSGPA
110 120 130 140 150 160
220 230 240 250 260 270
pF1KE4 RAVAVVSVLVVVISITIFCLETLPEFREDRE----LKVVRDPNLNMSKTVLSQTMFTDPF
: .:.:::.:..:::. ::::::: ::.. : :. : . ..: :::::
XP_011 RIIAIVSVMVILISIVSFCLETLPIFRDENEDMHGSGVTFHTYSNSTIGYQQSTSFTDPF
170 180 190 200 210 220
280 290 300 310 320 330
pF1KE4 FMVESTCIVWFTFELVLRFVVCPSKTDFFRNIMNIIDIISIIPYFATLITELVQETEPS-
:.::. ::.::.::...:: .::::. :: ::::::::..::::: :: :::... : .
XP_011 FIVETLCIIWFSFEFLVRFFACPSKAGFFTNIMNIIDIVAIIPYFITLGTELAEKPEDAQ
230 240 250 260 270 280
340 350 360 370 380
pF1KE4 -AQQNMSLAILRIIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILF
.:: :::::::.:::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILF
290 300 310 320 330 340
390 400 410 420 430 440
pF1KE4 SSAVYFAEVDEPESHFSSIPDGFWWAVVTMTTVGYGDMCPTTPGGKIVGTLCAIAGVLTI
::::::::.:: ::.: ::::.::::::.::::::::: ::: ::::::.::::::::::
XP_011 SSAVYFAEADERESQFPSIPDAFWWAVVSMTTVGYGDMVPTTIGGKIVGSLCAIAGVLTI
350 360 370 380 390 400
450 460 470 480 490 500
pF1KE4 ALPVPVIVSNFNYFYHRETENEEKQNIPGEIERILNSVGSRMGSTDSLNKTNGGCSTEKS
::::::::::::::::::::.::. . . . .. :. .:.:. .. . ::
XP_011 ALPVPVIVSNFNYFYHRETEGEEQA------QYLQVTSCPKIPSSPDLKKSRSASTISKS
410 420 430 440 450
510
pF1KE4 RK
XP_011 DYMEIQEGVNNSNEDFREENLKTANCTLANTNYVNITKMLTDV
460 470 480 490
>>XP_016856702 (OMIM: 176262,616366) PREDICTED: potassiu (499 aa)
initn: 1943 init1: 835 opt: 1940 Z-score: 1873.5 bits: 356.2 E(85289): 1.3e-97
Smith-Waterman score: 1940; 66.7% identity (83.1% similar) in 450 aa overlap (66-509:15-456)
40 50 60 70 80 90
pF1KE4 SPKGRPGGSSFSNGKILISESTNHETAFSKLPGDYADPPGPEPVVLNEGNQRVIINIAGL
::: : :: . .: .::.:::.::
XP_016 MTVATGDPADEAAALPGHPQDTYDPE--ADHECCERVVINISGL
10 20 30 40
100 110 120 130 140 150
pF1KE4 RFETQLRTLSQFPETLLGDREKRMQFFDSMRNEYFFDRNRPSFDGILYYYQSGGKIRRPA
::::::.::.::::::::: .:::..:: .::::::::::::::.:::::::::..:::.
XP_016 RFETQLKTLAQFPETLLGDPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPV
50 60 70 80 90 100
160 170 180 190 200 210
pF1KE4 NVPIDIFADEISFYELGSEAMDQFREDEGFIKDPETLLPTNDIHRQFWLLFEYPESSSAA
:::.:::..:: ::::: :::..::::::.::. : :: :...:: ::::::::::. :
XP_016 NVPLDIFSEEIRFYELGEEAMEMFREDEGYIKEEERPLPENEFQRQVWLLFEYPESSGPA
110 120 130 140 150 160
220 230 240 250 260 270
pF1KE4 RAVAVVSVLVVVISITIFCLETLPEFREDRE----LKVVRDPNLNMSKTVLSQTMFTDPF
: .:.:::.:..:::. ::::::: ::.. : :. : . ..: :::::
XP_016 RIIAIVSVMVILISIVSFCLETLPIFRDENEDMHGSGVTFHTYSNSTIGYQQSTSFTDPF
170 180 190 200 210 220
280 290 300 310 320 330
pF1KE4 FMVESTCIVWFTFELVLRFVVCPSKTDFFRNIMNIIDIISIIPYFATLITELVQETEPS-
:.::. ::.::.::...:: .::::. :: ::::::::..::::: :: :::... : .
XP_016 FIVETLCIIWFSFEFLVRFFACPSKAGFFTNIMNIIDIVAIIPYFITLGTELAEKPEDAQ
230 240 250 260 270 280
340 350 360 370 380
pF1KE4 -AQQNMSLAILRIIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILF
.:: :::::::.:::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILF
290 300 310 320 330 340
390 400 410 420 430 440
pF1KE4 SSAVYFAEVDEPESHFSSIPDGFWWAVVTMTTVGYGDMCPTTPGGKIVGTLCAIAGVLTI
::::::::.:: ::.: ::::.::::::.::::::::: ::: ::::::.::::::::::
XP_016 SSAVYFAEADERESQFPSIPDAFWWAVVSMTTVGYGDMVPTTIGGKIVGSLCAIAGVLTI
350 360 370 380 390 400
450 460 470 480 490 500
pF1KE4 ALPVPVIVSNFNYFYHRETENEEKQNIPGEIERILNSVGSRMGSTDSLNKTNGGCSTEKS
::::::::::::::::::::.::. . . . .. :. .:.:. .. . ::
XP_016 ALPVPVIVSNFNYFYHRETEGEEQA------QYLQVTSCPKIPSSPDLKKSRSASTISKS
410 420 430 440 450
510
pF1KE4 RK
XP_016 DYMEIQEGVNNSNEDFREENLKTANCTLANTNYVNITKMLTDV
460 470 480 490
>>XP_011539701 (OMIM: 176262,616366) PREDICTED: potassiu (499 aa)
initn: 1943 init1: 835 opt: 1940 Z-score: 1873.5 bits: 356.2 E(85289): 1.3e-97
Smith-Waterman score: 1940; 66.7% identity (83.1% similar) in 450 aa overlap (66-509:15-456)
40 50 60 70 80 90
pF1KE4 SPKGRPGGSSFSNGKILISESTNHETAFSKLPGDYADPPGPEPVVLNEGNQRVIINIAGL
::: : :: . .: .::.:::.::
XP_011 MTVATGDPADEAAALPGHPQDTYDPE--ADHECCERVVINISGL
10 20 30 40
100 110 120 130 140 150
pF1KE4 RFETQLRTLSQFPETLLGDREKRMQFFDSMRNEYFFDRNRPSFDGILYYYQSGGKIRRPA
::::::.::.::::::::: .:::..:: .::::::::::::::.:::::::::..:::.
XP_011 RFETQLKTLAQFPETLLGDPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPV
50 60 70 80 90 100
160 170 180 190 200 210
pF1KE4 NVPIDIFADEISFYELGSEAMDQFREDEGFIKDPETLLPTNDIHRQFWLLFEYPESSSAA
:::.:::..:: ::::: :::..::::::.::. : :: :...:: ::::::::::. :
XP_011 NVPLDIFSEEIRFYELGEEAMEMFREDEGYIKEEERPLPENEFQRQVWLLFEYPESSGPA
110 120 130 140 150 160
220 230 240 250 260 270
pF1KE4 RAVAVVSVLVVVISITIFCLETLPEFREDRE----LKVVRDPNLNMSKTVLSQTMFTDPF
: .:.:::.:..:::. ::::::: ::.. : :. : . ..: :::::
XP_011 RIIAIVSVMVILISIVSFCLETLPIFRDENEDMHGSGVTFHTYSNSTIGYQQSTSFTDPF
170 180 190 200 210 220
280 290 300 310 320 330
pF1KE4 FMVESTCIVWFTFELVLRFVVCPSKTDFFRNIMNIIDIISIIPYFATLITELVQETEPS-
:.::. ::.::.::...:: .::::. :: ::::::::..::::: :: :::... : .
XP_011 FIVETLCIIWFSFEFLVRFFACPSKAGFFTNIMNIIDIVAIIPYFITLGTELAEKPEDAQ
230 240 250 260 270 280
340 350 360 370 380
pF1KE4 -AQQNMSLAILRIIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILF
.:: :::::::.:::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILF
290 300 310 320 330 340
390 400 410 420 430 440
pF1KE4 SSAVYFAEVDEPESHFSSIPDGFWWAVVTMTTVGYGDMCPTTPGGKIVGTLCAIAGVLTI
::::::::.:: ::.: ::::.::::::.::::::::: ::: ::::::.::::::::::
XP_011 SSAVYFAEADERESQFPSIPDAFWWAVVSMTTVGYGDMVPTTIGGKIVGSLCAIAGVLTI
350 360 370 380 390 400
450 460 470 480 490 500
pF1KE4 ALPVPVIVSNFNYFYHRETENEEKQNIPGEIERILNSVGSRMGSTDSLNKTNGGCSTEKS
::::::::::::::::::::.::. . . . .. :. .:.:. .. . ::
XP_011 ALPVPVIVSNFNYFYHRETEGEEQA------QYLQVTSCPKIPSSPDLKKSRSASTISKS
410 420 430 440 450
510
pF1KE4 RK
XP_011 DYMEIQEGVNNSNEDFREENLKTANCTLANTNYVNITKMLTDV
460 470 480 490
>>XP_011539700 (OMIM: 176262,616366) PREDICTED: potassiu (499 aa)
initn: 1943 init1: 835 opt: 1940 Z-score: 1873.5 bits: 356.2 E(85289): 1.3e-97
Smith-Waterman score: 1940; 66.7% identity (83.1% similar) in 450 aa overlap (66-509:15-456)
40 50 60 70 80 90
pF1KE4 SPKGRPGGSSFSNGKILISESTNHETAFSKLPGDYADPPGPEPVVLNEGNQRVIINIAGL
::: : :: . .: .::.:::.::
XP_011 MTVATGDPADEAAALPGHPQDTYDPE--ADHECCERVVINISGL
10 20 30 40
100 110 120 130 140 150
pF1KE4 RFETQLRTLSQFPETLLGDREKRMQFFDSMRNEYFFDRNRPSFDGILYYYQSGGKIRRPA
::::::.::.::::::::: .:::..:: .::::::::::::::.:::::::::..:::.
XP_011 RFETQLKTLAQFPETLLGDPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPV
50 60 70 80 90 100
160 170 180 190 200 210
pF1KE4 NVPIDIFADEISFYELGSEAMDQFREDEGFIKDPETLLPTNDIHRQFWLLFEYPESSSAA
:::.:::..:: ::::: :::..::::::.::. : :: :...:: ::::::::::. :
XP_011 NVPLDIFSEEIRFYELGEEAMEMFREDEGYIKEEERPLPENEFQRQVWLLFEYPESSGPA
110 120 130 140 150 160
220 230 240 250 260 270
pF1KE4 RAVAVVSVLVVVISITIFCLETLPEFREDRE----LKVVRDPNLNMSKTVLSQTMFTDPF
: .:.:::.:..:::. ::::::: ::.. : :. : . ..: :::::
XP_011 RIIAIVSVMVILISIVSFCLETLPIFRDENEDMHGSGVTFHTYSNSTIGYQQSTSFTDPF
170 180 190 200 210 220
280 290 300 310 320 330
pF1KE4 FMVESTCIVWFTFELVLRFVVCPSKTDFFRNIMNIIDIISIIPYFATLITELVQETEPS-
:.::. ::.::.::...:: .::::. :: ::::::::..::::: :: :::... : .
XP_011 FIVETLCIIWFSFEFLVRFFACPSKAGFFTNIMNIIDIVAIIPYFITLGTELAEKPEDAQ
230 240 250 260 270 280
340 350 360 370 380
pF1KE4 -AQQNMSLAILRIIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILF
.:: :::::::.:::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILF
290 300 310 320 330 340
390 400 410 420 430 440
pF1KE4 SSAVYFAEVDEPESHFSSIPDGFWWAVVTMTTVGYGDMCPTTPGGKIVGTLCAIAGVLTI
::::::::.:: ::.: ::::.::::::.::::::::: ::: ::::::.::::::::::
XP_011 SSAVYFAEADERESQFPSIPDAFWWAVVSMTTVGYGDMVPTTIGGKIVGSLCAIAGVLTI
350 360 370 380 390 400
450 460 470 480 490 500
pF1KE4 ALPVPVIVSNFNYFYHRETENEEKQNIPGEIERILNSVGSRMGSTDSLNKTNGGCSTEKS
::::::::::::::::::::.::. . . . .. :. .:.:. .. . ::
XP_011 ALPVPVIVSNFNYFYHRETEGEEQA------QYLQVTSCPKIPSSPDLKKSRSASTISKS
410 420 430 440 450
510
pF1KE4 RK
XP_011 DYMEIQEGVNNSNEDFREENLKTANCTLANTNYVNITKMLTDV
460 470 480 490
>>XP_011539698 (OMIM: 176262,616366) PREDICTED: potassiu (499 aa)
initn: 1943 init1: 835 opt: 1940 Z-score: 1873.5 bits: 356.2 E(85289): 1.3e-97
Smith-Waterman score: 1940; 66.7% identity (83.1% similar) in 450 aa overlap (66-509:15-456)
40 50 60 70 80 90
pF1KE4 SPKGRPGGSSFSNGKILISESTNHETAFSKLPGDYADPPGPEPVVLNEGNQRVIINIAGL
::: : :: . .: .::.:::.::
XP_011 MTVATGDPADEAAALPGHPQDTYDPE--ADHECCERVVINISGL
10 20 30 40
100 110 120 130 140 150
pF1KE4 RFETQLRTLSQFPETLLGDREKRMQFFDSMRNEYFFDRNRPSFDGILYYYQSGGKIRRPA
::::::.::.::::::::: .:::..:: .::::::::::::::.:::::::::..:::.
XP_011 RFETQLKTLAQFPETLLGDPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPV
50 60 70 80 90 100
160 170 180 190 200 210
pF1KE4 NVPIDIFADEISFYELGSEAMDQFREDEGFIKDPETLLPTNDIHRQFWLLFEYPESSSAA
:::.:::..:: ::::: :::..::::::.::. : :: :...:: ::::::::::. :
XP_011 NVPLDIFSEEIRFYELGEEAMEMFREDEGYIKEEERPLPENEFQRQVWLLFEYPESSGPA
110 120 130 140 150 160
220 230 240 250 260 270
pF1KE4 RAVAVVSVLVVVISITIFCLETLPEFREDRE----LKVVRDPNLNMSKTVLSQTMFTDPF
: .:.:::.:..:::. ::::::: ::.. : :. : . ..: :::::
XP_011 RIIAIVSVMVILISIVSFCLETLPIFRDENEDMHGSGVTFHTYSNSTIGYQQSTSFTDPF
170 180 190 200 210 220
280 290 300 310 320 330
pF1KE4 FMVESTCIVWFTFELVLRFVVCPSKTDFFRNIMNIIDIISIIPYFATLITELVQETEPS-
:.::. ::.::.::...:: .::::. :: ::::::::..::::: :: :::... : .
XP_011 FIVETLCIIWFSFEFLVRFFACPSKAGFFTNIMNIIDIVAIIPYFITLGTELAEKPEDAQ
230 240 250 260 270 280
340 350 360 370 380
pF1KE4 -AQQNMSLAILRIIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILF
.:: :::::::.:::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILF
290 300 310 320 330 340
390 400 410 420 430 440
pF1KE4 SSAVYFAEVDEPESHFSSIPDGFWWAVVTMTTVGYGDMCPTTPGGKIVGTLCAIAGVLTI
::::::::.:: ::.: ::::.::::::.::::::::: ::: ::::::.::::::::::
XP_011 SSAVYFAEADERESQFPSIPDAFWWAVVSMTTVGYGDMVPTTIGGKIVGSLCAIAGVLTI
350 360 370 380 390 400
450 460 470 480 490 500
pF1KE4 ALPVPVIVSNFNYFYHRETENEEKQNIPGEIERILNSVGSRMGSTDSLNKTNGGCSTEKS
::::::::::::::::::::.::. . . . .. :. .:.:. .. . ::
XP_011 ALPVPVIVSNFNYFYHRETEGEEQA------QYLQVTSCPKIPSSPDLKKSRSASTISKS
410 420 430 440 450
510
pF1KE4 RK
XP_011 DYMEIQEGVNNSNEDFREENLKTANCTLANTNYVNITKMLTDV
460 470 480 490
>>NP_004965 (OMIM: 176262,616366) potassium voltage-gate (499 aa)
initn: 1943 init1: 835 opt: 1940 Z-score: 1873.5 bits: 356.2 E(85289): 1.3e-97
Smith-Waterman score: 1940; 66.7% identity (83.1% similar) in 450 aa overlap (66-509:15-456)
40 50 60 70 80 90
pF1KE4 SPKGRPGGSSFSNGKILISESTNHETAFSKLPGDYADPPGPEPVVLNEGNQRVIINIAGL
::: : :: . .: .::.:::.::
NP_004 MTVATGDPADEAAALPGHPQDTYDPE--ADHECCERVVINISGL
10 20 30 40
100 110 120 130 140 150
pF1KE4 RFETQLRTLSQFPETLLGDREKRMQFFDSMRNEYFFDRNRPSFDGILYYYQSGGKIRRPA
::::::.::.::::::::: .:::..:: .::::::::::::::.:::::::::..:::.
NP_004 RFETQLKTLAQFPETLLGDPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPV
50 60 70 80 90 100
160 170 180 190 200 210
pF1KE4 NVPIDIFADEISFYELGSEAMDQFREDEGFIKDPETLLPTNDIHRQFWLLFEYPESSSAA
:::.:::..:: ::::: :::..::::::.::. : :: :...:: ::::::::::. :
NP_004 NVPLDIFSEEIRFYELGEEAMEMFREDEGYIKEEERPLPENEFQRQVWLLFEYPESSGPA
110 120 130 140 150 160
220 230 240 250 260 270
pF1KE4 RAVAVVSVLVVVISITIFCLETLPEFREDRE----LKVVRDPNLNMSKTVLSQTMFTDPF
: .:.:::.:..:::. ::::::: ::.. : :. : . ..: :::::
NP_004 RIIAIVSVMVILISIVSFCLETLPIFRDENEDMHGSGVTFHTYSNSTIGYQQSTSFTDPF
170 180 190 200 210 220
280 290 300 310 320 330
pF1KE4 FMVESTCIVWFTFELVLRFVVCPSKTDFFRNIMNIIDIISIIPYFATLITELVQETEPS-
:.::. ::.::.::...:: .::::. :: ::::::::..::::: :: :::... : .
NP_004 FIVETLCIIWFSFEFLVRFFACPSKAGFFTNIMNIIDIVAIIPYFITLGTELAEKPEDAQ
230 240 250 260 270 280
340 350 360 370 380
pF1KE4 -AQQNMSLAILRIIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILF
.:: :::::::.:::::::::::::::::::::::::::::::::::::::::::::::
NP_004 QGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILF
290 300 310 320 330 340
390 400 410 420 430 440
pF1KE4 SSAVYFAEVDEPESHFSSIPDGFWWAVVTMTTVGYGDMCPTTPGGKIVGTLCAIAGVLTI
::::::::.:: ::.: ::::.::::::.::::::::: ::: ::::::.::::::::::
NP_004 SSAVYFAEADERESQFPSIPDAFWWAVVSMTTVGYGDMVPTTIGGKIVGSLCAIAGVLTI
350 360 370 380 390 400
450 460 470 480 490 500
pF1KE4 ALPVPVIVSNFNYFYHRETENEEKQNIPGEIERILNSVGSRMGSTDSLNKTNGGCSTEKS
::::::::::::::::::::.::. . . . .. :. .:.:. .. . ::
NP_004 ALPVPVIVSNFNYFYHRETEGEEQA------QYLQVTSCPKIPSSPDLKKSRSASTISKS
410 420 430 440 450
510
pF1KE4 RK
NP_004 DYMEIQEGVNNSNEDFREENLKTANCTLANTNYVNITKMLTDV
460 470 480 490
>>NP_002223 (OMIM: 176263) potassium voltage-gated chann (575 aa)
initn: 1924 init1: 836 opt: 1927 Z-score: 1860.2 bits: 354.0 E(85289): 7.1e-97
Smith-Waterman score: 1927; 70.8% identity (87.3% similar) in 408 aa overlap (73-473:90-496)
50 60 70 80 90 100
pF1KE4 GSSFSNGKILISESTNHETAFSKLPGDYADPPG-PEPVVLNEGNQRVIINIAGLRFETQL
::. : . ..::.:::.::::::::
NP_002 HLLEPEVADGGGAPPQGGCGGGGCDRYEPLPPSLPAAGEQDCCGERVVINISGLRFETQL
60 70 80 90 100 110
110 120 130 140 150 160
pF1KE4 RTLSQFPETLLGDREKRMQFFDSMRNEYFFDRNRPSFDGILYYYQSGGKIRRPANVPIDI
.:: ::::::::: ..::..:: .::::::::::::::.:::::::::.::::.::::::
NP_002 KTLCQFPETLLGDPKRRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRIRRPVNVPIDI
120 130 140 150 160 170
170 180 190 200 210 220
pF1KE4 FADEISFYELGSEAMDQFREDEGFIKDPETLLPTNDIHRQFWLLFEYPESSSAARAVAVV
:..:: ::.:: :::..:::::::... : :: :..:: ::::::::::. ::..:.:
NP_002 FSEEIRFYQLGEEAMEKFREDEGFLREEERPLPRRDFQRQVWLLFEYPESSGPARGIAIV
180 190 200 210 220 230
230 240 250 260 270
pF1KE4 SVLVVVISITIFCLETLPEFREDRELKVVRDPNL------NMSKTVLSQTMFTDPFFMVE
::::..:::.:::::::::::.... . . . . : . . . :.::::.::
NP_002 SVLVILISIVIFCLETLPEFRDEKDYPASTSQDSFEAAGNSTSGSRAGASSFSDPFFVVE
240 250 260 270 280 290
280 290 300 310 320 330
pF1KE4 STCIVWFTFELVLRFVVCPSKTDFFRNIMNIIDIISIIPYFATLITELVQETEPSAQQNM
. ::.::.:::..:: .::::. : :::::.:::..::::: :: :::. : . ..:: :
NP_002 TLCIIWFSFELLVRFFACPSKATFSRNIMNLIDIVAIIPYFITLGTELA-ERQGNGQQAM
300 310 320 330 340 350
340 350 360 370 380 390
pF1KE4 SLAILRIIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYF
::::::.:::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 SLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYF
360 370 380 390 400 410
400 410 420 430 440 450
pF1KE4 AEVDEPESHFSSIPDGFWWAVVTMTTVGYGDMCPTTPGGKIVGTLCAIAGVLTIALPVPV
::.:.: : ::::::.:::::::::::::::: :.: ::::::.::::::::::::::::
NP_002 AEADDPTSGFSSIPDAFWWAVVTMTTVGYGDMHPVTIGGKIVGSLCAIAGVLTIALPVPV
420 430 440 450 460 470
460 470 480 490 500 510
pF1KE4 IVSNFNYFYHRETENEEKQNIPGEIERILNSVGSRMGSTDSLNKTNGGCSTEKSRK
::::::::::::::.::.
NP_002 IVSNFNYFYHRETEGEEQSQYMHVGSCQHLSSSAEELRKARSNSTLSKSEYMVIEEGGMN
480 490 500 510 520 530
511 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 17:02:14 2016 done: Mon Nov 7 17:02:15 2016
Total Scan time: 9.640 Total Display time: 0.090
Function used was FASTA [36.3.4 Apr, 2011]