Result of FASTA (ccds) for
pFN21AE4112
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE4112, 483 aa
1>>>pF1KE4112 483 - 483 aa - 483 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.6785+/-0.000913; mu= 7.2765+/- 0.055
mean_var=133.5397+/-26.795, 0's: 0 Z-trim(109.5): 28 B-trim: 24 in 1/52
Lambda= 0.110986
statistics sampled from 10943 (10962) to 10943 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.69), E-opt: 0.2 (0.337), width: 16
Scan time: 2.890
The best scores are: opt bits E(32554)
CCDS73261.1 BTBD10 gene_id:84280|Hs108|chr11 ( 483) 3225 527.9 9.5e-150
CCDS7811.1 BTBD10 gene_id:84280|Hs108|chr11 ( 475) 2967 486.5 2.6e-137
CCDS76388.1 BTBD10 gene_id:84280|Hs108|chr11 ( 427) 2867 470.5 1.5e-132
CCDS4821.1 KCTD20 gene_id:222658|Hs108|chr6 ( 419) 1605 268.4 1e-71
CCDS69097.1 KCTD20 gene_id:222658|Hs108|chr6 ( 274) 1456 244.5 1.1e-64
CCDS69096.1 KCTD20 gene_id:222658|Hs108|chr6 ( 253) 1025 175.5 6.1e-44
>>CCDS73261.1 BTBD10 gene_id:84280|Hs108|chr11 (483 aa)
initn: 3225 init1: 3225 opt: 3225 Z-score: 2801.9 bits: 527.9 E(32554): 9.5e-150
Smith-Waterman score: 3225; 100.0% identity (100.0% similar) in 483 aa overlap (1-483:1-483)
10 20 30 40 50 60
pF1KE4 MPKDADLAFSASLFERAESLYTLISKFFSCFCVSTLAYTKGSTSSRIAKGGVDHTKMSLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 MPKDADLAFSASLFERAESLYTLISKFFSCFCVSTLAYTKGSTSSRIAKGGVDHTKMSLH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 GASGGHERSRDRRRSSDRSRDSSHERTESQLTPCIRNVTSPTRQHHVEREKDHSSSRPSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 GASGGHERSRDRRRSSDRSRDSSHERTESQLTPCIRNVTSPTRQHHVEREKDHSSSRPSS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 PRPQKASPNGSISSAGNSSRNSSQSSSDGSCKTAGEMVFVYENAKEGARNIRTSERVTLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 PRPQKASPNGSISSAGNSSRNSSQSSSDGSCKTAGEMVFVYENAKEGARNIRTSERVTLI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 VDNTRFVVDPSIFTAQPNTMLGRMFGSGREHNFTRPNEKGEYEVAEGIGSTVFRAILDYY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 VDNTRFVVDPSIFTAQPNTMLGRMFGSGREHNFTRPNEKGEYEVAEGIGSTVFRAILDYY
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 KTGIIRCPDGISIPELREACDYLCISFEYSTIKCRDLSALMHELSNDGARRQFEFYLEEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 KTGIIRCPDGISIPELREACDYLCISFEYSTIKCRDLSALMHELSNDGARRQFEFYLEEM
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 ILPLMVASAQSGERECHIVVLTDDDVVDWDEEYPPQMGEEYSQIIYSTKLYRFFKYIENR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 ILPLMVASAQSGERECHIVVLTDDDVVDWDEEYPPQMGEEYSQIIYSTKLYRFFKYIENR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 DVAKSVLKERGLKKIRLGIEGYPTYKEKVKKRPGGRPEVIYNYVQRPFIRMSWEKEEGKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 DVAKSVLKERGLKKIRLGIEGYPTYKEKVKKRPGGRPEVIYNYVQRPFIRMSWEKEEGKS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE4 RHVDFQCVKSKSITNLAAAAADIPQDQLVVMHPTPQVDELDILPIHPPSGNSDLDPDAQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 RHVDFQCVKSKSITNLAAAAADIPQDQLVVMHPTPQVDELDILPIHPPSGNSDLDPDAQN
430 440 450 460 470 480
pF1KE4 PML
:::
CCDS73 PML
>>CCDS7811.1 BTBD10 gene_id:84280|Hs108|chr11 (475 aa)
initn: 2967 init1: 2967 opt: 2967 Z-score: 2578.7 bits: 486.5 E(32554): 2.6e-137
Smith-Waterman score: 2967; 99.3% identity (99.8% similar) in 446 aa overlap (38-483:30-475)
10 20 30 40 50 60
pF1KE4 AFSASLFERAESLYTLISKFFSCFCVSTLAYTKGSTSSRIAKGGVDHTKMSLHGASGGHE
: ..::::::::::::::::::::::::::
CCDS78 MAGRPHPYDGNSSDPENWDRKLHSRPRKLYKHSSTSSRIAKGGVDHTKMSLHGASGGHE
10 20 30 40 50
70 80 90 100 110 120
pF1KE4 RSRDRRRSSDRSRDSSHERTESQLTPCIRNVTSPTRQHHVEREKDHSSSRPSSPRPQKAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS78 RSRDRRRSSDRSRDSSHERTESQLTPCIRNVTSPTRQHHVEREKDHSSSRPSSPRPQKAS
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE4 PNGSISSAGNSSRNSSQSSSDGSCKTAGEMVFVYENAKEGARNIRTSERVTLIVDNTRFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS78 PNGSISSAGNSSRNSSQSSSDGSCKTAGEMVFVYENAKEGARNIRTSERVTLIVDNTRFV
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE4 VDPSIFTAQPNTMLGRMFGSGREHNFTRPNEKGEYEVAEGIGSTVFRAILDYYKTGIIRC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS78 VDPSIFTAQPNTMLGRMFGSGREHNFTRPNEKGEYEVAEGIGSTVFRAILDYYKTGIIRC
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE4 PDGISIPELREACDYLCISFEYSTIKCRDLSALMHELSNDGARRQFEFYLEEMILPLMVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS78 PDGISIPELREACDYLCISFEYSTIKCRDLSALMHELSNDGARRQFEFYLEEMILPLMVA
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE4 SAQSGERECHIVVLTDDDVVDWDEEYPPQMGEEYSQIIYSTKLYRFFKYIENRDVAKSVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS78 SAQSGERECHIVVLTDDDVVDWDEEYPPQMGEEYSQIIYSTKLYRFFKYIENRDVAKSVL
300 310 320 330 340 350
370 380 390 400 410 420
pF1KE4 KERGLKKIRLGIEGYPTYKEKVKKRPGGRPEVIYNYVQRPFIRMSWEKEEGKSRHVDFQC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS78 KERGLKKIRLGIEGYPTYKEKVKKRPGGRPEVIYNYVQRPFIRMSWEKEEGKSRHVDFQC
360 370 380 390 400 410
430 440 450 460 470 480
pF1KE4 VKSKSITNLAAAAADIPQDQLVVMHPTPQVDELDILPIHPPSGNSDLDPDAQNPML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS78 VKSKSITNLAAAAADIPQDQLVVMHPTPQVDELDILPIHPPSGNSDLDPDAQNPML
420 430 440 450 460 470
>>CCDS76388.1 BTBD10 gene_id:84280|Hs108|chr11 (427 aa)
initn: 2867 init1: 2867 opt: 2867 Z-score: 2492.9 bits: 470.5 E(32554): 1.5e-132
Smith-Waterman score: 2867; 100.0% identity (100.0% similar) in 427 aa overlap (57-483:1-427)
30 40 50 60 70 80
pF1KE4 FFSCFCVSTLAYTKGSTSSRIAKGGVDHTKMSLHGASGGHERSRDRRRSSDRSRDSSHER
::::::::::::::::::::::::::::::
CCDS76 MSLHGASGGHERSRDRRRSSDRSRDSSHER
10 20 30
90 100 110 120 130 140
pF1KE4 TESQLTPCIRNVTSPTRQHHVEREKDHSSSRPSSPRPQKASPNGSISSAGNSSRNSSQSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS76 TESQLTPCIRNVTSPTRQHHVEREKDHSSSRPSSPRPQKASPNGSISSAGNSSRNSSQSS
40 50 60 70 80 90
150 160 170 180 190 200
pF1KE4 SDGSCKTAGEMVFVYENAKEGARNIRTSERVTLIVDNTRFVVDPSIFTAQPNTMLGRMFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS76 SDGSCKTAGEMVFVYENAKEGARNIRTSERVTLIVDNTRFVVDPSIFTAQPNTMLGRMFG
100 110 120 130 140 150
210 220 230 240 250 260
pF1KE4 SGREHNFTRPNEKGEYEVAEGIGSTVFRAILDYYKTGIIRCPDGISIPELREACDYLCIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS76 SGREHNFTRPNEKGEYEVAEGIGSTVFRAILDYYKTGIIRCPDGISIPELREACDYLCIS
160 170 180 190 200 210
270 280 290 300 310 320
pF1KE4 FEYSTIKCRDLSALMHELSNDGARRQFEFYLEEMILPLMVASAQSGERECHIVVLTDDDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS76 FEYSTIKCRDLSALMHELSNDGARRQFEFYLEEMILPLMVASAQSGERECHIVVLTDDDV
220 230 240 250 260 270
330 340 350 360 370 380
pF1KE4 VDWDEEYPPQMGEEYSQIIYSTKLYRFFKYIENRDVAKSVLKERGLKKIRLGIEGYPTYK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS76 VDWDEEYPPQMGEEYSQIIYSTKLYRFFKYIENRDVAKSVLKERGLKKIRLGIEGYPTYK
280 290 300 310 320 330
390 400 410 420 430 440
pF1KE4 EKVKKRPGGRPEVIYNYVQRPFIRMSWEKEEGKSRHVDFQCVKSKSITNLAAAAADIPQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS76 EKVKKRPGGRPEVIYNYVQRPFIRMSWEKEEGKSRHVDFQCVKSKSITNLAAAAADIPQD
340 350 360 370 380 390
450 460 470 480
pF1KE4 QLVVMHPTPQVDELDILPIHPPSGNSDLDPDAQNPML
:::::::::::::::::::::::::::::::::::::
CCDS76 QLVVMHPTPQVDELDILPIHPPSGNSDLDPDAQNPML
400 410 420
>>CCDS4821.1 KCTD20 gene_id:222658|Hs108|chr6 (419 aa)
initn: 1644 init1: 1594 opt: 1605 Z-score: 1401.0 bits: 268.4 E(32554): 1e-71
Smith-Waterman score: 1618; 60.0% identity (80.0% similar) in 415 aa overlap (80-475:5-419)
50 60 70 80 90 100
pF1KE4 GGVDHTKMSLHGASGGHERSRDRRRSSDRSRDSSHERTESQLTPCIRNVTSPTRQHH---
: :. .: : . :. . : . :..
CCDS48 MNVHRGSDSDRLLRQEASCLVDDTLAVAQEKEAN
10 20 30
110 120 130 140 150
pF1KE4 -VEREKDHSSSRPSSPRPQKASPNGSISSAGNSSRNSSQSSSD--GSCKTAGEMV----F
. :. . : .:: . : . . . :. . . . : ::: .:. :
CCDS48 SLASSGPHNLTYPLGPRNEDLSLDYASQPANLQFPHIMPLAEDIKGSCFQSGNKRNHEPF
40 50 60 70 80 90
160 170 180 190 200 210
pF1KE4 V----YENAKEG---ARNIRTSERVTLIVDNTRFVVDPSIFTAQPNTMLGRMFGSGREHN
. . :.. : . .. :.:::.::.:::::.:.::::.:.:::::::: :::.:
CCDS48 IAPERFGNSSVGFGSNSHSQAPEKVTLLVDGTRFVVNPQIFTAHPDTMLGRMFGPGREYN
100 110 120 130 140 150
220 230 240 250 260 270
pF1KE4 FTRPNEKGEYEVAEGIGSTVFRAILDYYKTGIIRCPDGISIPELREACDYLCISFEYSTI
:::::::::::.::::..::::..::::::::: ::::::::.::..::::::.:...::
CCDS48 FTRPNEKGEYEIAEGISATVFRTVLDYYKTGIINCPDGISIPDLRDTCDYLCINFDFNTI
160 170 180 190 200 210
280 290 300 310 320 330
pF1KE4 KCRDLSALMHELSNDGARRQFEFYLEEMILPLMVASAQSGERECHIVVLTDDDVVDWDEE
.:.:::::.::::::::..::. ::::.:::.::. :..::::::::::::.: :::::.
CCDS48 RCQDLSALLHELSNDGAHKQFDHYLEELILPIMVGCAKKGERECHIVVLTDEDSVDWDED
220 230 240 250 260 270
340 350 360 370 380 390
pF1KE4 YPPQMGEEYSQIIYSTKLYRFFKYIENRDVAKSVLKERGLKKIRLGIEGYPTYKEKVKKR
.:: ::::::::.::.::::::::::::::::.::::::::.::.::::::: :::.:.:
CCDS48 HPPPMGEEYSQILYSSKLYRFFKYIENRDVAKTVLKERGLKNIRIGIEGYPTCKEKIKRR
280 290 300 310 320 330
400 410 420 430 440 450
pF1KE4 PGGRPEVIYNYVQRPFIRMSWEKEEGKSRHVDFQCVKSKSITNLAAAAADIPQDQLVVMH
:::: ::::::::::::.::::::::::::::::::.:::.:::.::. :. .:: ..::
CCDS48 PGGRSEVIYNYVQRPFIQMSWEKEEGKSRHVDFQCVRSKSLTNLVAAGDDVLEDQEILMH
340 350 360 370 380 390
460 470 480
pF1KE4 PTPQVDELDIL--PIHPPSGNSDLDPDAQNPML
::::::: : :. ..:. :
CCDS48 HPPQVDELDRLNAPLSQMASNDFQD
400 410
>>CCDS69097.1 KCTD20 gene_id:222658|Hs108|chr6 (274 aa)
initn: 1476 init1: 1454 opt: 1456 Z-score: 1274.9 bits: 244.5 E(32554): 1.1e-64
Smith-Waterman score: 1456; 75.2% identity (92.3% similar) in 274 aa overlap (204-475:1-274)
180 190 200 210 220 230
pF1KE4 SERVTLIVDNTRFVVDPSIFTAQPNTMLGRMFGSGREHNFTRPNEKGEYEVAEGIGSTVF
::: :::.::::::::::::.::::..:::
CCDS69 MFGPGREYNFTRPNEKGEYEIAEGISATVF
10 20 30
240 250 260 270 280 290
pF1KE4 RAILDYYKTGIIRCPDGISIPELREACDYLCISFEYSTIKCRDLSALMHELSNDGARRQF
:..::::::::: ::::::::.::..::::::.:...::.:.:::::.::::::::..::
CCDS69 RTVLDYYKTGIINCPDGISIPDLRDTCDYLCINFDFNTIRCQDLSALLHELSNDGAHKQF
40 50 60 70 80 90
300 310 320 330 340 350
pF1KE4 EFYLEEMILPLMVASAQSGERECHIVVLTDDDVVDWDEEYPPQMGEEYSQIIYSTKLYRF
. ::::.:::.::. :..::::::::::::.: :::::..:: ::::::::.::.:::::
CCDS69 DHYLEELILPIMVGCAKKGERECHIVVLTDEDSVDWDEDHPPPMGEEYSQILYSSKLYRF
100 110 120 130 140 150
360 370 380 390 400 410
pF1KE4 FKYIENRDVAKSVLKERGLKKIRLGIEGYPTYKEKVKKRPGGRPEVIYNYVQRPFIRMSW
:::::::::::.::::::::.::.::::::: :::.:.::::: ::::::::::::.:::
CCDS69 FKYIENRDVAKTVLKERGLKNIRIGIEGYPTCKEKIKRRPGGRSEVIYNYVQRPFIQMSW
160 170 180 190 200 210
420 430 440 450 460 470
pF1KE4 EKEEGKSRHVDFQCVKSKSITNLAAAAADIPQDQLVVMHPTPQVDELDIL--PIHPPSGN
:::::::::::::::.:::.:::.::. :. .:: ..:: ::::::: : :. ..:
CCDS69 EKEEGKSRHVDFQCVRSKSLTNLVAAGDDVLEDQEILMHHPPQVDELDRLNAPLSQMASN
220 230 240 250 260 270
480
pF1KE4 SDLDPDAQNPML
. :
CCDS69 DFQD
>>CCDS69096.1 KCTD20 gene_id:222658|Hs108|chr6 (253 aa)
initn: 1045 init1: 1017 opt: 1025 Z-score: 902.4 bits: 175.5 E(32554): 6.1e-44
Smith-Waterman score: 1025; 73.4% identity (90.1% similar) in 203 aa overlap (275-475:51-253)
250 260 270 280 290 300
pF1KE4 IRCPDGISIPELREACDYLCISFEYSTIKCRDLSALMHELSNDGARRQFEFYLEEMILPL
:. .::.::::::::..::. ::::.:::.
CCDS69 VDDTLAVAQEKEANSLASSGPHNLTYPLGPRNEGALLHELSNDGAHKQFDHYLEELILPI
30 40 50 60 70 80
310 320 330 340 350 360
pF1KE4 MVASAQSGERECHIVVLTDDDVVDWDEEYPPQMGEEYSQIIYSTKLYRFFKYIENRDVAK
::. :..::::::::::::.: :::::..:: ::::::::.::.::::::::::::::::
CCDS69 MVGCAKKGERECHIVVLTDEDSVDWDEDHPPPMGEEYSQILYSSKLYRFFKYIENRDVAK
90 100 110 120 130 140
370 380 390 400 410 420
pF1KE4 SVLKERGLKKIRLGIEGYPTYKEKVKKRPGGRPEVIYNYVQRPFIRMSWEKEEGKSRHVD
.::::::::.::.::::::: :::.:.::::: ::::::::::::.::::::::::::::
CCDS69 TVLKERGLKNIRIGIEGYPTCKEKIKRRPGGRSEVIYNYVQRPFIQMSWEKEEGKSRHVD
150 160 170 180 190 200
430 440 450 460 470 480
pF1KE4 FQCVKSKSITNLAAAAADIPQDQLVVMHPTPQVDELDIL--PIHPPSGNSDLDPDAQNPM
::::.:::.:::.::. :. .:: ..:: ::::::: : :. ..:. :
CCDS69 FQCVRSKSLTNLVAAGDDVLEDQEILMHHPPQVDELDRLNAPLSQMASNDFQD
210 220 230 240 250
pF1KE4 L
483 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 03:24:01 2016 done: Sun Nov 6 03:24:01 2016
Total Scan time: 2.890 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]