Result of FASTA (omim) for
pFN21AE4108
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE4108, 478 aa
1>>>pF1KE4108 478 - 478 aa - 478 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.4747+/-0.000406; mu= 12.7951+/- 0.025
mean_var=182.4821+/-40.334, 0's: 0 Z-trim(116.7): 126 B-trim: 394 in 2/54
Lambda= 0.094943
statistics sampled from 27881 (28062) to 27881 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.7), E-opt: 0.2 (0.329), width: 16
Scan time: 7.630
The best scores are: opt bits E(85289)
NP_742024 (OMIM: 608308) ankyrin repeat and BTB/PO ( 478) 3273 461.3 2.6e-129
XP_006713832 (OMIM: 608308) PREDICTED: ankyrin rep ( 480) 3150 444.5 3.1e-124
NP_115937 (OMIM: 608308) ankyrin repeat and BTB/PO ( 336) 2288 326.2 8.6e-89
XP_016862776 (OMIM: 608308) PREDICTED: ankyrin rep ( 336) 2288 326.2 8.6e-89
XP_011511515 (OMIM: 608308) PREDICTED: ankyrin rep ( 336) 2288 326.2 8.6e-89
XP_016862777 (OMIM: 608308) PREDICTED: ankyrin rep ( 297) 1798 259.0 1.3e-68
XP_016862775 (OMIM: 608308) PREDICTED: ankyrin rep ( 414) 1798 259.2 1.6e-68
XP_016862774 (OMIM: 608308) PREDICTED: ankyrin rep ( 439) 1798 259.2 1.6e-68
NP_001316524 (OMIM: 608778,615081) kelch-like prot ( 608) 214 42.5 0.0041
NP_689680 (OMIM: 608778,615081) kelch-like protein ( 608) 214 42.5 0.0041
>>NP_742024 (OMIM: 608308) ankyrin repeat and BTB/POZ do (478 aa)
initn: 3273 init1: 3273 opt: 3273 Z-score: 2442.5 bits: 461.3 E(85289): 2.6e-129
Smith-Waterman score: 3273; 100.0% identity (100.0% similar) in 478 aa overlap (1-478:1-478)
10 20 30 40 50 60
pF1KE4 MDTSDLFASCRKGDVGRVRYLLEQRDVEVNVRDKWDSTPLYYACLCGHEELVLYLLANGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_742 MDTSDLFASCRKGDVGRVRYLLEQRDVEVNVRDKWDSTPLYYACLCGHEELVLYLLANGA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 RCEANTFDGERCLYGALSDPIRRALRDYKQVTASCRRRDYYDDFLQRLLEQGIHSDVVFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_742 RCEANTFDGERCLYGALSDPIRRALRDYKQVTASCRRRDYYDDFLQRLLEQGIHSDVVFV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 VHGKPFRVHRCVLGARSAYFANMLDTKWKGKSVVVLRHPLINPVAFGALLQYLYTGRLDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_742 VHGKPFRVHRCVLGARSAYFANMLDTKWKGKSVVVLRHPLINPVAFGALLQYLYTGRLDI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 GVEHVSDCERLAKQCQLWDLLSDLEAKCEKVSEFVASKPGTCVKVLTIEPPPADPRLRED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_742 GVEHVSDCERLAKQCQLWDLLSDLEAKCEKVSEFVASKPGTCVKVLTIEPPPADPRLRED
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 MALLADCALPPELRGDLWELPFPCPDGFNSCPDICFRVAGCSFLCHKAFFCGRSDYFRAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_742 MALLADCALPPELRGDLWELPFPCPDGFNSCPDICFRVAGCSFLCHKAFFCGRSDYFRAL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 LDDHFRESEEPATSGGPPAVTLHGISPDVFTHVLYYMYSDHTELSPEAAYDVLSVADMYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_742 LDDHFRESEEPATSGGPPAVTLHGISPDVFTHVLYYMYSDHTELSPEAAYDVLSVADMYL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 LPGLKRLCGRSLAQMLDEDTVVGVWRVAKLFRLARLEDQCTEYMAKVIEKLVEREDFVEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_742 LPGLKRLCGRSLAQMLDEDTVVGVWRVAKLFRLARLEDQCTEYMAKVIEKLVEREDFVEA
370 380 390 400 410 420
430 440 450 460 470
pF1KE4 VKEEAAAVAARQETDSIPLVDDIRFHVASTVQTYSAIEEAQQRLRALEDLLVSIGLDC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_742 VKEEAAAVAARQETDSIPLVDDIRFHVASTVQTYSAIEEAQQRLRALEDLLVSIGLDC
430 440 450 460 470
>>XP_006713832 (OMIM: 608308) PREDICTED: ankyrin repeat (480 aa)
initn: 3150 init1: 3150 opt: 3150 Z-score: 2351.5 bits: 444.5 E(85289): 3.1e-124
Smith-Waterman score: 3150; 100.0% identity (100.0% similar) in 460 aa overlap (19-478:21-480)
10 20 30 40 50
pF1KE4 MDTSDLFASCRKGDVGRVRYLLEQRDVEVNVRDKWDSTPLYYACLCGHEELVLYLLAN
::::::::::::::::::::::::::::::::::::::::
XP_006 MWAECDHEPVLTQALTSFLPRYLLEQRDVEVNVRDKWDSTPLYYACLCGHEELVLYLLAN
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE4 GARCEANTFDGERCLYGALSDPIRRALRDYKQVTASCRRRDYYDDFLQRLLEQGIHSDVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GARCEANTFDGERCLYGALSDPIRRALRDYKQVTASCRRRDYYDDFLQRLLEQGIHSDVV
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE4 FVVHGKPFRVHRCVLGARSAYFANMLDTKWKGKSVVVLRHPLINPVAFGALLQYLYTGRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FVVHGKPFRVHRCVLGARSAYFANMLDTKWKGKSVVVLRHPLINPVAFGALLQYLYTGRL
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE4 DIGVEHVSDCERLAKQCQLWDLLSDLEAKCEKVSEFVASKPGTCVKVLTIEPPPADPRLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DIGVEHVSDCERLAKQCQLWDLLSDLEAKCEKVSEFVASKPGTCVKVLTIEPPPADPRLR
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE4 EDMALLADCALPPELRGDLWELPFPCPDGFNSCPDICFRVAGCSFLCHKAFFCGRSDYFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EDMALLADCALPPELRGDLWELPFPCPDGFNSCPDICFRVAGCSFLCHKAFFCGRSDYFR
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE4 ALLDDHFRESEEPATSGGPPAVTLHGISPDVFTHVLYYMYSDHTELSPEAAYDVLSVADM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ALLDDHFRESEEPATSGGPPAVTLHGISPDVFTHVLYYMYSDHTELSPEAAYDVLSVADM
310 320 330 340 350 360
360 370 380 390 400 410
pF1KE4 YLLPGLKRLCGRSLAQMLDEDTVVGVWRVAKLFRLARLEDQCTEYMAKVIEKLVEREDFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YLLPGLKRLCGRSLAQMLDEDTVVGVWRVAKLFRLARLEDQCTEYMAKVIEKLVEREDFV
370 380 390 400 410 420
420 430 440 450 460 470
pF1KE4 EAVKEEAAAVAARQETDSIPLVDDIRFHVASTVQTYSAIEEAQQRLRALEDLLVSIGLDC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EAVKEEAAAVAARQETDSIPLVDDIRFHVASTVQTYSAIEEAQQRLRALEDLLVSIGLDC
430 440 450 460 470 480
>>NP_115937 (OMIM: 608308) ankyrin repeat and BTB/POZ do (336 aa)
initn: 2288 init1: 2288 opt: 2288 Z-score: 1715.1 bits: 326.2 E(85289): 8.6e-89
Smith-Waterman score: 2288; 100.0% identity (100.0% similar) in 336 aa overlap (143-478:1-336)
120 130 140 150 160 170
pF1KE4 IHSDVVFVVHGKPFRVHRCVLGARSAYFANMLDTKWKGKSVVVLRHPLINPVAFGALLQY
::::::::::::::::::::::::::::::
NP_115 MLDTKWKGKSVVVLRHPLINPVAFGALLQY
10 20 30
180 190 200 210 220 230
pF1KE4 LYTGRLDIGVEHVSDCERLAKQCQLWDLLSDLEAKCEKVSEFVASKPGTCVKVLTIEPPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 LYTGRLDIGVEHVSDCERLAKQCQLWDLLSDLEAKCEKVSEFVASKPGTCVKVLTIEPPP
40 50 60 70 80 90
240 250 260 270 280 290
pF1KE4 ADPRLREDMALLADCALPPELRGDLWELPFPCPDGFNSCPDICFRVAGCSFLCHKAFFCG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 ADPRLREDMALLADCALPPELRGDLWELPFPCPDGFNSCPDICFRVAGCSFLCHKAFFCG
100 110 120 130 140 150
300 310 320 330 340 350
pF1KE4 RSDYFRALLDDHFRESEEPATSGGPPAVTLHGISPDVFTHVLYYMYSDHTELSPEAAYDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 RSDYFRALLDDHFRESEEPATSGGPPAVTLHGISPDVFTHVLYYMYSDHTELSPEAAYDV
160 170 180 190 200 210
360 370 380 390 400 410
pF1KE4 LSVADMYLLPGLKRLCGRSLAQMLDEDTVVGVWRVAKLFRLARLEDQCTEYMAKVIEKLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 LSVADMYLLPGLKRLCGRSLAQMLDEDTVVGVWRVAKLFRLARLEDQCTEYMAKVIEKLV
220 230 240 250 260 270
420 430 440 450 460 470
pF1KE4 EREDFVEAVKEEAAAVAARQETDSIPLVDDIRFHVASTVQTYSAIEEAQQRLRALEDLLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 EREDFVEAVKEEAAAVAARQETDSIPLVDDIRFHVASTVQTYSAIEEAQQRLRALEDLLV
280 290 300 310 320 330
pF1KE4 SIGLDC
::::::
NP_115 SIGLDC
>>XP_016862776 (OMIM: 608308) PREDICTED: ankyrin repeat (336 aa)
initn: 2288 init1: 2288 opt: 2288 Z-score: 1715.1 bits: 326.2 E(85289): 8.6e-89
Smith-Waterman score: 2288; 100.0% identity (100.0% similar) in 336 aa overlap (143-478:1-336)
120 130 140 150 160 170
pF1KE4 IHSDVVFVVHGKPFRVHRCVLGARSAYFANMLDTKWKGKSVVVLRHPLINPVAFGALLQY
::::::::::::::::::::::::::::::
XP_016 MLDTKWKGKSVVVLRHPLINPVAFGALLQY
10 20 30
180 190 200 210 220 230
pF1KE4 LYTGRLDIGVEHVSDCERLAKQCQLWDLLSDLEAKCEKVSEFVASKPGTCVKVLTIEPPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LYTGRLDIGVEHVSDCERLAKQCQLWDLLSDLEAKCEKVSEFVASKPGTCVKVLTIEPPP
40 50 60 70 80 90
240 250 260 270 280 290
pF1KE4 ADPRLREDMALLADCALPPELRGDLWELPFPCPDGFNSCPDICFRVAGCSFLCHKAFFCG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ADPRLREDMALLADCALPPELRGDLWELPFPCPDGFNSCPDICFRVAGCSFLCHKAFFCG
100 110 120 130 140 150
300 310 320 330 340 350
pF1KE4 RSDYFRALLDDHFRESEEPATSGGPPAVTLHGISPDVFTHVLYYMYSDHTELSPEAAYDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RSDYFRALLDDHFRESEEPATSGGPPAVTLHGISPDVFTHVLYYMYSDHTELSPEAAYDV
160 170 180 190 200 210
360 370 380 390 400 410
pF1KE4 LSVADMYLLPGLKRLCGRSLAQMLDEDTVVGVWRVAKLFRLARLEDQCTEYMAKVIEKLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSVADMYLLPGLKRLCGRSLAQMLDEDTVVGVWRVAKLFRLARLEDQCTEYMAKVIEKLV
220 230 240 250 260 270
420 430 440 450 460 470
pF1KE4 EREDFVEAVKEEAAAVAARQETDSIPLVDDIRFHVASTVQTYSAIEEAQQRLRALEDLLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EREDFVEAVKEEAAAVAARQETDSIPLVDDIRFHVASTVQTYSAIEEAQQRLRALEDLLV
280 290 300 310 320 330
pF1KE4 SIGLDC
::::::
XP_016 SIGLDC
>>XP_011511515 (OMIM: 608308) PREDICTED: ankyrin repeat (336 aa)
initn: 2288 init1: 2288 opt: 2288 Z-score: 1715.1 bits: 326.2 E(85289): 8.6e-89
Smith-Waterman score: 2288; 100.0% identity (100.0% similar) in 336 aa overlap (143-478:1-336)
120 130 140 150 160 170
pF1KE4 IHSDVVFVVHGKPFRVHRCVLGARSAYFANMLDTKWKGKSVVVLRHPLINPVAFGALLQY
::::::::::::::::::::::::::::::
XP_011 MLDTKWKGKSVVVLRHPLINPVAFGALLQY
10 20 30
180 190 200 210 220 230
pF1KE4 LYTGRLDIGVEHVSDCERLAKQCQLWDLLSDLEAKCEKVSEFVASKPGTCVKVLTIEPPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LYTGRLDIGVEHVSDCERLAKQCQLWDLLSDLEAKCEKVSEFVASKPGTCVKVLTIEPPP
40 50 60 70 80 90
240 250 260 270 280 290
pF1KE4 ADPRLREDMALLADCALPPELRGDLWELPFPCPDGFNSCPDICFRVAGCSFLCHKAFFCG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ADPRLREDMALLADCALPPELRGDLWELPFPCPDGFNSCPDICFRVAGCSFLCHKAFFCG
100 110 120 130 140 150
300 310 320 330 340 350
pF1KE4 RSDYFRALLDDHFRESEEPATSGGPPAVTLHGISPDVFTHVLYYMYSDHTELSPEAAYDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RSDYFRALLDDHFRESEEPATSGGPPAVTLHGISPDVFTHVLYYMYSDHTELSPEAAYDV
160 170 180 190 200 210
360 370 380 390 400 410
pF1KE4 LSVADMYLLPGLKRLCGRSLAQMLDEDTVVGVWRVAKLFRLARLEDQCTEYMAKVIEKLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSVADMYLLPGLKRLCGRSLAQMLDEDTVVGVWRVAKLFRLARLEDQCTEYMAKVIEKLV
220 230 240 250 260 270
420 430 440 450 460 470
pF1KE4 EREDFVEAVKEEAAAVAARQETDSIPLVDDIRFHVASTVQTYSAIEEAQQRLRALEDLLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EREDFVEAVKEEAAAVAARQETDSIPLVDDIRFHVASTVQTYSAIEEAQQRLRALEDLLV
280 290 300 310 320 330
pF1KE4 SIGLDC
::::::
XP_011 SIGLDC
>>XP_016862777 (OMIM: 608308) PREDICTED: ankyrin repeat (297 aa)
initn: 2003 init1: 1798 opt: 1798 Z-score: 1352.9 bits: 259.0 E(85289): 1.3e-68
Smith-Waterman score: 1929; 88.4% identity (88.4% similar) in 336 aa overlap (143-478:1-297)
120 130 140 150 160 170
pF1KE4 IHSDVVFVVHGKPFRVHRCVLGARSAYFANMLDTKWKGKSVVVLRHPLINPVAFGALLQY
::::::::::::::::::::::::::::::
XP_016 MLDTKWKGKSVVVLRHPLINPVAFGALLQY
10 20 30
180 190 200 210 220 230
pF1KE4 LYTGRLDIGVEHVSDCERLAKQCQLWDLLSDLEAKCEKVSEFVASKPGTCVKVLTIEPPP
::: ::::::::::::::::::
XP_016 LYT---------------------------------------VASKPGTCVKVLTIEPPP
40 50
240 250 260 270 280 290
pF1KE4 ADPRLREDMALLADCALPPELRGDLWELPFPCPDGFNSCPDICFRVAGCSFLCHKAFFCG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ADPRLREDMALLADCALPPELRGDLWELPFPCPDGFNSCPDICFRVAGCSFLCHKAFFCG
60 70 80 90 100 110
300 310 320 330 340 350
pF1KE4 RSDYFRALLDDHFRESEEPATSGGPPAVTLHGISPDVFTHVLYYMYSDHTELSPEAAYDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RSDYFRALLDDHFRESEEPATSGGPPAVTLHGISPDVFTHVLYYMYSDHTELSPEAAYDV
120 130 140 150 160 170
360 370 380 390 400 410
pF1KE4 LSVADMYLLPGLKRLCGRSLAQMLDEDTVVGVWRVAKLFRLARLEDQCTEYMAKVIEKLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSVADMYLLPGLKRLCGRSLAQMLDEDTVVGVWRVAKLFRLARLEDQCTEYMAKVIEKLV
180 190 200 210 220 230
420 430 440 450 460 470
pF1KE4 EREDFVEAVKEEAAAVAARQETDSIPLVDDIRFHVASTVQTYSAIEEAQQRLRALEDLLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EREDFVEAVKEEAAAVAARQETDSIPLVDDIRFHVASTVQTYSAIEEAQQRLRALEDLLV
240 250 260 270 280 290
pF1KE4 SIGLDC
::::::
XP_016 SIGLDC
>>XP_016862775 (OMIM: 608308) PREDICTED: ankyrin repeat (414 aa)
initn: 2715 init1: 1798 opt: 1798 Z-score: 1351.3 bits: 259.2 E(85289): 1.6e-68
Smith-Waterman score: 2647; 90.3% identity (90.6% similar) in 445 aa overlap (35-478:9-414)
10 20 30 40 50 60
pF1KE4 DLFASCRKGDVGRVRYLLEQRDVEVNVRDKWDS-TPLYYACLCGHEELVLYLLANGARCE
:.: : :::::::::::::::::::::::
XP_016 MWAECGTCWSSETWRYYACLCGHEELVLYLLANGARCE
10 20 30
70 80 90 100 110 120
pF1KE4 ANTFDGERCLYGALSDPIRRALRDYKQVTASCRRRDYYDDFLQRLLEQGIHSDVVFVVHG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ANTFDGERCLYGALSDPIRRALRDYKQVTASCRRRDYYDDFLQRLLEQGIHSDVVFVVHG
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE4 KPFRVHRCVLGARSAYFANMLDTKWKGKSVVVLRHPLINPVAFGALLQYLYTGRLDIGVE
::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KPFRVHRCVLGARSAYFANMLDTKWKGKSVVVLRHPLINPVAFGALLQYLYT--------
100 110 120 130 140 150
190 200 210 220 230 240
pF1KE4 HVSDCERLAKQCQLWDLLSDLEAKCEKVSEFVASKPGTCVKVLTIEPPPADPRLREDMAL
:::::::::::::::::::::::::::::
XP_016 -------------------------------VASKPGTCVKVLTIEPPPADPRLREDMAL
160 170
250 260 270 280 290 300
pF1KE4 LADCALPPELRGDLWELPFPCPDGFNSCPDICFRVAGCSFLCHKAFFCGRSDYFRALLDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LADCALPPELRGDLWELPFPCPDGFNSCPDICFRVAGCSFLCHKAFFCGRSDYFRALLDD
180 190 200 210 220 230
310 320 330 340 350 360
pF1KE4 HFRESEEPATSGGPPAVTLHGISPDVFTHVLYYMYSDHTELSPEAAYDVLSVADMYLLPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HFRESEEPATSGGPPAVTLHGISPDVFTHVLYYMYSDHTELSPEAAYDVLSVADMYLLPG
240 250 260 270 280 290
370 380 390 400 410 420
pF1KE4 LKRLCGRSLAQMLDEDTVVGVWRVAKLFRLARLEDQCTEYMAKVIEKLVEREDFVEAVKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKRLCGRSLAQMLDEDTVVGVWRVAKLFRLARLEDQCTEYMAKVIEKLVEREDFVEAVKE
300 310 320 330 340 350
430 440 450 460 470
pF1KE4 EAAAVAARQETDSIPLVDDIRFHVASTVQTYSAIEEAQQRLRALEDLLVSIGLDC
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EAAAVAARQETDSIPLVDDIRFHVASTVQTYSAIEEAQQRLRALEDLLVSIGLDC
360 370 380 390 400 410
>>XP_016862774 (OMIM: 608308) PREDICTED: ankyrin repeat (439 aa)
initn: 2988 init1: 1798 opt: 1798 Z-score: 1351.0 bits: 259.2 E(85289): 1.6e-68
Smith-Waterman score: 2914; 91.8% identity (91.8% similar) in 478 aa overlap (1-478:1-439)
10 20 30 40 50 60
pF1KE4 MDTSDLFASCRKGDVGRVRYLLEQRDVEVNVRDKWDSTPLYYACLCGHEELVLYLLANGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MDTSDLFASCRKGDVGRVRYLLEQRDVEVNVRDKWDSTPLYYACLCGHEELVLYLLANGA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 RCEANTFDGERCLYGALSDPIRRALRDYKQVTASCRRRDYYDDFLQRLLEQGIHSDVVFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RCEANTFDGERCLYGALSDPIRRALRDYKQVTASCRRRDYYDDFLQRLLEQGIHSDVVFV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 VHGKPFRVHRCVLGARSAYFANMLDTKWKGKSVVVLRHPLINPVAFGALLQYLYTGRLDI
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VHGKPFRVHRCVLGARSAYFANMLDTKWKGKSVVVLRHPLINPVAFGALLQYLYT-----
130 140 150 160 170
190 200 210 220 230 240
pF1KE4 GVEHVSDCERLAKQCQLWDLLSDLEAKCEKVSEFVASKPGTCVKVLTIEPPPADPRLRED
::::::::::::::::::::::::::
XP_016 ----------------------------------VASKPGTCVKVLTIEPPPADPRLRED
180 190 200
250 260 270 280 290 300
pF1KE4 MALLADCALPPELRGDLWELPFPCPDGFNSCPDICFRVAGCSFLCHKAFFCGRSDYFRAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MALLADCALPPELRGDLWELPFPCPDGFNSCPDICFRVAGCSFLCHKAFFCGRSDYFRAL
210 220 230 240 250 260
310 320 330 340 350 360
pF1KE4 LDDHFRESEEPATSGGPPAVTLHGISPDVFTHVLYYMYSDHTELSPEAAYDVLSVADMYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LDDHFRESEEPATSGGPPAVTLHGISPDVFTHVLYYMYSDHTELSPEAAYDVLSVADMYL
270 280 290 300 310 320
370 380 390 400 410 420
pF1KE4 LPGLKRLCGRSLAQMLDEDTVVGVWRVAKLFRLARLEDQCTEYMAKVIEKLVEREDFVEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LPGLKRLCGRSLAQMLDEDTVVGVWRVAKLFRLARLEDQCTEYMAKVIEKLVEREDFVEA
330 340 350 360 370 380
430 440 450 460 470
pF1KE4 VKEEAAAVAARQETDSIPLVDDIRFHVASTVQTYSAIEEAQQRLRALEDLLVSIGLDC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VKEEAAAVAARQETDSIPLVDDIRFHVASTVQTYSAIEEAQQRLRALEDLLVSIGLDC
390 400 410 420 430
>>NP_001316524 (OMIM: 608778,615081) kelch-like protein (608 aa)
initn: 168 init1: 97 opt: 214 Z-score: 176.9 bits: 42.5 E(85289): 0.0041
Smith-Waterman score: 216; 24.0% identity (55.9% similar) in 204 aa overlap (235-435:15-196)
210 220 230 240 250 260
pF1KE4 EAKCEKVSEFVASKPGTCVKVLTIEPPPADPRLREDMALLADCALPPELR--GDLWELPF
:.... :. .: : . ::: : :
NP_001 MEMESAAASTRFHQPHMERKMSAMA-CEIFNELRLEGKL-----
10 20 30
270 280 290 300 310 320
pF1KE4 PCPDGFNSCPDICFRVAGCSFLCHKAFFCGRSDYFRALLDDHFRESEEPATSGGPPAVTL
: :. ..: : : :: ..:. :.:::::. . . ..:. . . .
NP_001 -C--------DVVIKVNGFEFSAHKNILCSCSSYFRALFTSGWNNTEKKVYN-------I
40 50 60 70 80
330 340 350 360 370 380
pF1KE4 HGISPDVFTHVLYYMYSDHTELSPEAAYDVLSVADMYLLPGLKRLCGRSLAQMLDEDTVV
:::::.. .. : :. . ..:. . .:..::.. . :. : : . : . : :. .
NP_001 PGISPDMMKLIIEYAYTRTVPITPDNVEKLLAAADQFNIMGIVRGCCEFLKSELCLDNCI
90 100 110 120 130 140
390 400 410 420 430 440
pF1KE4 GVWRVAKLFRLARLEDQCTEYMAKVIEKLVE-REDFVEAVKEEAAAVAARQETDSIPLVD
:. . . . .:... .. . .:..:. .:.: : . ..: .
NP_001 GICKFTDYYYCPELRQKAYMFILHNFEEMVKVSAEFLELSVTELKDIIEKDELNVKQEDA
150 160 170 180 190 200
450 460 470
pF1KE4 DIRFHVASTVQTYSAIEEAQQRLRALEDLLVSIGLDC
NP_001 VFEAILKWISHDPQNRKQHISILLPKVRLALMHAEYFMNNVKMNDYVKDSEECKPVIINA
210 220 230 240 250 260
>>NP_689680 (OMIM: 608778,615081) kelch-like protein 10 (608 aa)
initn: 168 init1: 97 opt: 214 Z-score: 176.9 bits: 42.5 E(85289): 0.0041
Smith-Waterman score: 216; 24.0% identity (55.9% similar) in 204 aa overlap (235-435:15-196)
210 220 230 240 250 260
pF1KE4 EAKCEKVSEFVASKPGTCVKVLTIEPPPADPRLREDMALLADCALPPELR--GDLWELPF
:.... :. .: : . ::: : :
NP_689 MEMESAAASTRFHQPHMERKMSAMA-CEIFNELRLEGKL-----
10 20 30
270 280 290 300 310 320
pF1KE4 PCPDGFNSCPDICFRVAGCSFLCHKAFFCGRSDYFRALLDDHFRESEEPATSGGPPAVTL
: :. ..: : : :: ..:. :.:::::. . . ..:. . . .
NP_689 -C--------DVVIKVNGFEFSAHKNILCSCSSYFRALFTSGWNNTEKKVYN-------I
40 50 60 70 80
330 340 350 360 370 380
pF1KE4 HGISPDVFTHVLYYMYSDHTELSPEAAYDVLSVADMYLLPGLKRLCGRSLAQMLDEDTVV
:::::.. .. : :. . ..:. . .:..::.. . :. : : . : . : :. .
NP_689 PGISPDMMKLIIEYAYTRTVPITPDNVEKLLAAADQFNIMGIVRGCCEFLKSELCLDNCI
90 100 110 120 130 140
390 400 410 420 430 440
pF1KE4 GVWRVAKLFRLARLEDQCTEYMAKVIEKLVE-REDFVEAVKEEAAAVAARQETDSIPLVD
:. . . . .:... .. . .:..:. .:.: : . ..: .
NP_689 GICKFTDYYYCPELRQKAYMFILHNFEEMVKVSAEFLELSVTELKDIIEKDELNVKQEDA
150 160 170 180 190 200
450 460 470
pF1KE4 DIRFHVASTVQTYSAIEEAQQRLRALEDLLVSIGLDC
NP_689 VFEAILKWISHDPQNRKQHISILLPKVRLALMHAEYFMNNVKMNDYVKDSEECKPVIINA
210 220 230 240 250 260
478 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 01:54:00 2016 done: Sun Nov 6 01:54:01 2016
Total Scan time: 7.630 Total Display time: 0.050
Function used was FASTA [36.3.4 Apr, 2011]