Result of FASTA (omim) for
pFN21AE4090
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE4090, 456 aa
1>>>pF1KE4090 456 - 456 aa - 456 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.3923+/-0.000304; mu= 18.2614+/- 0.019
mean_var=92.5655+/-18.442, 0's: 0 Z-trim(119.5): 283 B-trim: 460 in 2/54
Lambda= 0.133306
statistics sampled from 33219 (33580) to 33219 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.727), E-opt: 0.2 (0.394), width: 16
Scan time: 10.570
The best scores are: opt bits E(85289)
NP_114092 (OMIM: 176268) potassium voltage-gated c ( 456) 3109 607.9 1.8e-173
NP_002223 (OMIM: 176263) potassium voltage-gated c ( 575) 1958 386.6 9.1e-107
NP_002224 (OMIM: 176266) potassium voltage-gated c ( 653) 1910 377.5 6e-104
XP_016856702 (OMIM: 176262,616366) PREDICTED: pota ( 499) 1884 372.3 1.6e-102
XP_011539702 (OMIM: 176262,616366) PREDICTED: pota ( 499) 1884 372.3 1.6e-102
XP_011539699 (OMIM: 176262,616366) PREDICTED: pota ( 499) 1884 372.3 1.6e-102
XP_011539698 (OMIM: 176262,616366) PREDICTED: pota ( 499) 1884 372.3 1.6e-102
XP_011539701 (OMIM: 176262,616366) PREDICTED: pota ( 499) 1884 372.3 1.6e-102
XP_011539700 (OMIM: 176262,616366) PREDICTED: pota ( 499) 1884 372.3 1.6e-102
NP_004965 (OMIM: 176262,616366) potassium voltage- ( 499) 1884 372.3 1.6e-102
NP_000208 (OMIM: 160120,176260) potassium voltage- ( 495) 1156 232.3 2.2e-60
NP_001191198 (OMIM: 176262,616366) potassium volta ( 356) 1139 228.9 1.7e-59
NP_002225 (OMIM: 176267,612240) potassium voltage- ( 613) 1118 225.1 4.1e-58
NP_005540 (OMIM: 602420) potassium voltage-gated c ( 511) 1081 217.9 5e-56
XP_016874761 (OMIM: 176257) PREDICTED: potassium v ( 529) 864 176.2 1.9e-43
XP_005253743 (OMIM: 176257) PREDICTED: potassium v ( 529) 864 176.2 1.9e-43
XP_011519257 (OMIM: 176257) PREDICTED: potassium v ( 529) 864 176.2 1.9e-43
NP_002226 (OMIM: 176257) potassium voltage-gated c ( 529) 864 176.2 1.9e-43
XP_016874760 (OMIM: 176257) PREDICTED: potassium v ( 529) 864 176.2 1.9e-43
XP_016874759 (OMIM: 176257) PREDICTED: potassium v ( 529) 864 176.2 1.9e-43
NP_004966 (OMIM: 600397,616056) potassium voltage- ( 858) 755 155.4 5.4e-37
XP_006723847 (OMIM: 600397,616056) PREDICTED: pota ( 858) 755 155.4 5.4e-37
XP_011527101 (OMIM: 600397,616056) PREDICTED: pota ( 858) 755 155.4 5.4e-37
NP_004761 (OMIM: 607738) potassium voltage-gated c ( 911) 753 155.1 7.3e-37
NP_036413 (OMIM: 605410) potassium voltage-gated c ( 630) 656 136.3 2.3e-31
XP_016884998 (OMIM: 300281) PREDICTED: potassium v ( 558) 653 135.6 3.2e-31
XP_016884997 (OMIM: 300281) PREDICTED: potassium v ( 558) 653 135.6 3.2e-31
XP_006710694 (OMIM: 605411,607346,616399) PREDICTE ( 510) 652 135.4 3.4e-31
XP_011542212 (OMIM: 300281) PREDICTED: potassium v ( 647) 653 135.7 3.5e-31
NP_004970 (OMIM: 300281) potassium voltage-gated c ( 647) 653 135.7 3.5e-31
XP_006710693 (OMIM: 605411,607346,616399) PREDICTE ( 636) 652 135.5 4e-31
NP_751948 (OMIM: 605411,607346,616399) potassium v ( 636) 652 135.5 4e-31
XP_006710692 (OMIM: 605411,607346,616399) PREDICTE ( 655) 652 135.5 4.1e-31
XP_016856733 (OMIM: 605411,607346,616399) PREDICTE ( 655) 652 135.5 4.1e-31
XP_005270908 (OMIM: 605411,607346,616399) PREDICTE ( 655) 652 135.5 4.1e-31
NP_004971 (OMIM: 605411,607346,616399) potassium v ( 655) 652 135.5 4.1e-31
XP_016869471 (OMIM: 607738) PREDICTED: potassium v ( 666) 652 135.5 4.1e-31
XP_016869470 (OMIM: 607738) PREDICTED: potassium v ( 666) 652 135.5 4.1e-31
XP_016859548 (OMIM: 603888) PREDICTED: potassium v ( 491) 640 133.1 1.6e-30
NP_001269357 (OMIM: 603888) potassium voltage-gate ( 491) 640 133.1 1.6e-30
XP_011531127 (OMIM: 603888) PREDICTED: potassium v ( 491) 640 133.1 1.6e-30
NP_002243 (OMIM: 603888) potassium voltage-gated c ( 491) 640 133.1 1.6e-30
NP_065748 (OMIM: 602906) potassium voltage-gated c ( 477) 633 131.7 4.1e-30
XP_011525230 (OMIM: 176264,605259) PREDICTED: pota ( 728) 631 131.5 7.2e-30
XP_011525228 (OMIM: 176264,605259) PREDICTED: pota ( 757) 631 131.5 7.4e-30
NP_004968 (OMIM: 176264,605259) potassium voltage- ( 757) 631 131.5 7.4e-30
XP_006723266 (OMIM: 176264,605259) PREDICTED: pota ( 757) 631 131.5 7.4e-30
XP_011525227 (OMIM: 176264,605259) PREDICTED: pota ( 768) 631 131.5 7.5e-30
NP_001309728 (OMIM: 602905) potassium voltage-gate ( 526) 628 130.8 8.5e-30
NP_002242 (OMIM: 602905) potassium voltage-gated c ( 526) 628 130.8 8.5e-30
>>NP_114092 (OMIM: 176268) potassium voltage-gated chann (456 aa)
initn: 3109 init1: 3109 opt: 3109 Z-score: 3235.4 bits: 607.9 E(85289): 1.8e-173
Smith-Waterman score: 3109; 100.0% identity (100.0% similar) in 456 aa overlap (1-456:1-456)
10 20 30 40 50 60
pF1KE4 MEPRCPPPCGCCERLVLNVAGLRFETRARTLGRFPDTLLGDPARRGRFYDDARREYFFDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_114 MEPRCPPPCGCCERLVLNVAGLRFETRARTLGRFPDTLLGDPARRGRFYDDARREYFFDR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 HRPSFDAVLYYYQSGGRLRRPAHVPLDVFLEEVAFYGLGAAALARLREDEGCPVPPERPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_114 HRPSFDAVLYYYQSGGRLRRPAHVPLDVFLEEVAFYGLGAAALARLREDEGCPVPPERPL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 PRRAFARQLWLLFEFPESSQAARVLAVVSVLVILVSIVVFCLETLPDFRDDRDGTGLAAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_114 PRRAFARQLWLLFEFPESSQAARVLAVVSVLVILVSIVVFCLETLPDFRDDRDGTGLAAA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 AAAGPFPAPLNGSSQMPGNPPRLPFNDPFFVVETLCICWFSFELLVRLLVCPSKAIFFKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_114 AAAGPFPAPLNGSSQMPGNPPRLPFNDPFFVVETLCICWFSFELLVRLLVCPSKAIFFKN
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 VMNLIDFVAILPYFVALGTELARQRGVGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_114 VMNLIDFVAILPYFVALGTELARQRGVGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 LGQTLRASMRELGLLIFFLFIGVVLFSSAVYFAEVDRVDSHFTSIPESFWWAVVTMTTVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_114 LGQTLRASMRELGLLIFFLFIGVVLFSSAVYFAEVDRVDSHFTSIPESFWWAVVTMTTVG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 YGDMAPVTVGGKIVGSLCAIAGVLTISLPVPVIVSNFSYFYHRETEGEEAGMFSHVDMQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_114 YGDMAPVTVGGKIVGSLCAIAGVLTISLPVPVIVSNFSYFYHRETEGEEAGMFSHVDMQP
370 380 390 400 410 420
430 440 450
pF1KE4 CGPLEGKANGGLVDGEVPELPPPLWAPPGKHLVTEV
::::::::::::::::::::::::::::::::::::
NP_114 CGPLEGKANGGLVDGEVPELPPPLWAPPGKHLVTEV
430 440 450
>>NP_002223 (OMIM: 176263) potassium voltage-gated chann (575 aa)
initn: 1950 init1: 1178 opt: 1958 Z-score: 2037.8 bits: 386.6 E(85289): 9.1e-107
Smith-Waterman score: 1958; 69.1% identity (83.8% similar) in 433 aa overlap (2-428:87-512)
10 20
pF1KE4 MEPRCP--PPCG---CC-ERLVLNVAGLRFE
:: : : : :: ::.:.:..:::::
NP_002 PGDHLLEPEVADGGGAPPQGGCGGGGCDRYEPLPPSLPAAGEQDCCGERVVINISGLRFE
60 70 80 90 100 110
30 40 50 60 70 80
pF1KE4 TRARTLGRFPDTLLGDPARRGRFYDDARREYFFDRHRPSFDAVLYYYQSGGRLRRPAHVP
:. .:: .::.:::::: :: :..: : ::::::.::::::.:::::::::.:::..::
NP_002 TQLKTLCQFPETLLGDPKRRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRIRRPVNVP
120 130 140 150 160 170
90 100 110 120 130 140
pF1KE4 LDVFLEEVAFYGLGAAALARLREDEGCPVPPERPLPRRAFARQLWLLFEFPESSQAARVL
.:.: ::. :: :: :. ..::::: ::::::: : ::.:::::.:::: :: .
NP_002 IDIFSEEIRFYQLGEEAMEKFREDEGFLREEERPLPRRDFQRQVWLLFEYPESSGPARGI
180 190 200 210 220 230
150 160 170 180 190 200
pF1KE4 AVVSVLVILVSIVVFCLETLPDFRDDRDGTGLAAAAAAGPFPAPLNGSSQMPGNPPRLPF
:.:::::::.:::.:::::::.:::..: :... : : :..: .. :
NP_002 AIVSVLVILISIVIFCLETLPEFRDEKD---YPASTSQDSFEAAGNSTSGSRAGAS--SF
240 250 260 270 280 290
210 220 230 240 250 260
pF1KE4 NDPFFVVETLCICWFSFELLVRLLVCPSKAIFFKNVMNLIDFVAILPYFVALGTELARQR
.::::::::::: :::::::::...::::: : .:.:::::.:::.:::..::::::...
NP_002 SDPFFVVETLCIIWFSFELLVRFFACPSKATFSRNIMNLIDIVAIIPYFITLGTELAERQ
300 310 320 330 340 350
270 280 290 300 310 320
pF1KE4 GVGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLRASMRELGLLIFFLFIGVVL
: ::::::::::::::::::::::::::::::::::::::.:::::::::::::::::.:
NP_002 GNGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVIL
360 370 380 390 400 410
330 340 350 360 370 380
pF1KE4 FSSAVYFAEVDRVDSHFTSIPESFWWAVVTMTTVGYGDMAPVTVGGKIVGSLCAIAGVLT
:::::::::.: : :.:::..:::::::::::::::: :::.::::::::::::::::
NP_002 FSSAVYFAEADDPTSGFSSIPDAFWWAVVTMTTVGYGDMHPVTIGGKIVGSLCAIAGVLT
420 430 440 450 460 470
390 400 410 420 430 440
pF1KE4 ISLPVPVIVSNFSYFYHRETEGEEAGMFSHVDMQPCGPLEGKANGGLVDGEVPELPPPLW
:.::::::::::.::::::::::: ... :: : : ..:
NP_002 IALPVPVIVSNFNYFYHRETEGEEQSQYMHVG--SCQHLSSSAEELRKARSNSTLSKSEY
480 490 500 510 520
450
pF1KE4 APPGKHLVTEV
NP_002 MVIEEGGMNHSAFPQTPFKTGNSTATCTTNNNPNSCVNIKKIFTDV
530 540 550 560 570
>>NP_002224 (OMIM: 176266) potassium voltage-gated chann (653 aa)
initn: 1944 init1: 821 opt: 1910 Z-score: 1987.2 bits: 377.5 E(85289): 6e-104
Smith-Waterman score: 1910; 69.4% identity (86.4% similar) in 412 aa overlap (11-415:174-581)
10 20 30 40
pF1KE4 MEPRCPPPCGCCERLVLNVAGLRFETRARTLGRFPDTLLG
::::.:.::.::::::. .::..::.::::
NP_002 EDDHGDECSYTDLLPQDEGGGGYSSVRYSDCCERVVINVSGLRFETQMKTLAQFPETLLG
150 160 170 180 190 200
50 60 70 80 90 100
pF1KE4 DPARRGRFYDDARREYFFDRHRPSFDAVLYYYQSGGRLRRPAHVPLDVFLEEVAFYGLGA
:: .: ...: : ::::::.::::::.::::::::::.::..::.:.: ::: :: ::
NP_002 DPEKRTQYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLKRPVNVPFDIFTEEVKFYQLGE
210 220 230 240 250 260
110 120 130 140 150
pF1KE4 AALARLREDEGCPVPPE-RPLPRRAFARQLWLLFEFPESSQAARVLAVVSVLVILVSIVV
:: ..::::: : : ::. : .:.:::::.::::. :: .:.:::::::.:::.
NP_002 EALLKFREDEGFVREEEDRALPENEFKKQIWLLFEYPESSSPARGIAIVSVLVILISIVI
270 280 290 300 310 320
160 170 180 190 200 210
pF1KE4 FCLETLPDFRDDRDGTGLAAAAAAGPFPAPLNGSSQMPG--NPPRLPFNDPFFVVETLCI
:::::::.:::::: :. : .:: . :: .: : : . ::::::.:::.::
NP_002 FCLETLPEFRDDRD---LVMALSAGGHGGLLNDTSA-PHLENSGHTIFNDPFFIVETVCI
330 340 350 360 370
220 230 240 250 260 270
pF1KE4 CWFSFELLVRLLVCPSKAIFFKNVMNLIDFVAILPYFVALGTELARQRGVG----QQAMS
:::::..:: ..:::.:.::::.::.::.:.:::::..:::.::.:.: : :::::
NP_002 VWFSFEFVVRCFACPSQALFFKNIMNIIDIVSILPYFITLGTDLAQQQGGGNGQQQQAMS
380 390 400 410 420 430
280 290 300 310 320 330
pF1KE4 LAILRVIRLVRVFRIFKLSRHSKGLQILGQTLRASMRELGLLIFFLFIGVVLFSSAVYFA
.::::.:::::::::::::::::::::::.::::::::::::::::::::.:::::::::
NP_002 FAILRIIRLVRVFRIFKLSRHSKGLQILGHTLRASMRELGLLIFFLFIGVILFSSAVYFA
440 450 460 470 480 490
340 350 360 370 380 390
pF1KE4 EVDRVDSHFTSIPESFWWAVVTMTTVGYGDMAPVTVGGKIVGSLCAIAGVLTISLPVPVI
:.:. .:: :::..:::::::::::::::: :.:::::::::::::::::::.::::::
NP_002 EADEPTTHFQSIPDAFWWAVVTMTTVGYGDMKPITVGGKIVGSLCAIAGVLTIALPVPVI
500 510 520 530 540 550
400 410 420 430 440 450
pF1KE4 VSNFSYFYHRETEGEEAGMFSHVDMQPCGPLEGKANGGLVDGEVPELPPPLWAPPGKHLV
::::.::::::::.:: ....
NP_002 VSNFNYFYHRETENEEQTQLTQNAVSCPYLPSNLLKKFRSSTSSSLGDKSEYLEMEEGVK
560 570 580 590 600 610
>>XP_016856702 (OMIM: 176262,616366) PREDICTED: potassiu (499 aa)
initn: 1928 init1: 839 opt: 1884 Z-score: 1961.7 bits: 372.3 E(85289): 1.6e-102
Smith-Waterman score: 1884; 68.0% identity (83.8% similar) in 419 aa overlap (11-423:31-439)
10 20 30 40
pF1KE4 MEPRCPPPCGCCERLVLNVAGLRFETRARTLGRFPDTLLG
::::.:.:..::::::. .::..::.::::
XP_016 MTVATGDPADEAAALPGHPQDTYDPEADHECCERVVINISGLRFETQLKTLAQFPETLLG
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE4 DPARRGRFYDDARREYFFDRHRPSFDAVLYYYQSGGRLRRPAHVPLDVFLEEVAFYGLGA
:: .: :..: : ::::::.::::::.:::::::::::::..::::.: ::. :: ::
XP_016 DPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDIFSEEIRFYELGE
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE4 AALARLREDEGCPVPPERPLPRRAFARQLWLLFEFPESSQAARVLAVVSVLVILVSIVVF
:. .::::: :::::. : ::.:::::.:::: ::..:.:::.:::.::: :
XP_016 EAMEMFREDEGYIKEEERPLPENEFQRQVWLLFEYPESSGPARIIAIVSVMVILISIVSF
130 140 150 160 170 180
170 180 190 200 210
pF1KE4 CLETLPDFRD---DRDGTGLAAAAAAGPFPAPLNGSSQMPGNPPRLPFNDPFFVVETLCI
:::::: ::: : :.:.. : . :.. : :.::::.::::::
XP_016 CLETLPIFRDENEDMHGSGVT-------FHTYSNST---IGYQQSTSFTDPFFIVETLCI
190 200 210 220 230
220 230 240 250 260 270
pF1KE4 CWFSFELLVRLLVCPSKAIFFKNVMNLIDFVAILPYFVALGTELARQ---RGVGQQAMSL
:::::.:::...::::: :: :.::.::.:::.:::..::::::.. :::::::
XP_016 IWFSFEFLVRFFACPSKAGFFTNIMNIIDIVAIIPYFITLGTELAEKPEDAQQGQQAMSL
240 250 260 270 280 290
280 290 300 310 320 330
pF1KE4 AILRVIRLVRVFRIFKLSRHSKGLQILGQTLRASMRELGLLIFFLFIGVVLFSSAVYFAE
:::::::::::::::::::::::::::::::.:::::::::::::::::.::::::::::
XP_016 AILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAE
300 310 320 330 340 350
340 350 360 370 380 390
pF1KE4 VDRVDSHFTSIPESFWWAVVTMTTVGYGDMAPVTVGGKIVGSLCAIAGVLTISLPVPVIV
.:. .:.: :::..::::::.:::::::::.:.:.:::::::::::::::::.:::::::
XP_016 ADERESQFPSIPDAFWWAVVSMTTVGYGDMVPTTIGGKIVGSLCAIAGVLTIALPVPVIV
360 370 380 390 400 410
400 410 420 430 440 450
pF1KE4 SNFSYFYHRETEGEEAGMFSHVDMQPCGPLEGKANGGLVDGEVPELPPPLWAPPGKHLVT
:::.::::::::::: ... .: : :
XP_016 SNFNYFYHRETEGEEQAQYLQVTSCPKIPSSPDLKKSRSASTISKSDYMEIQEGVNNSNE
420 430 440 450 460 470
>>XP_011539702 (OMIM: 176262,616366) PREDICTED: potassiu (499 aa)
initn: 1928 init1: 839 opt: 1884 Z-score: 1961.7 bits: 372.3 E(85289): 1.6e-102
Smith-Waterman score: 1884; 68.0% identity (83.8% similar) in 419 aa overlap (11-423:31-439)
10 20 30 40
pF1KE4 MEPRCPPPCGCCERLVLNVAGLRFETRARTLGRFPDTLLG
::::.:.:..::::::. .::..::.::::
XP_011 MTVATGDPADEAAALPGHPQDTYDPEADHECCERVVINISGLRFETQLKTLAQFPETLLG
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE4 DPARRGRFYDDARREYFFDRHRPSFDAVLYYYQSGGRLRRPAHVPLDVFLEEVAFYGLGA
:: .: :..: : ::::::.::::::.:::::::::::::..::::.: ::. :: ::
XP_011 DPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDIFSEEIRFYELGE
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE4 AALARLREDEGCPVPPERPLPRRAFARQLWLLFEFPESSQAARVLAVVSVLVILVSIVVF
:. .::::: :::::. : ::.:::::.:::: ::..:.:::.:::.::: :
XP_011 EAMEMFREDEGYIKEEERPLPENEFQRQVWLLFEYPESSGPARIIAIVSVMVILISIVSF
130 140 150 160 170 180
170 180 190 200 210
pF1KE4 CLETLPDFRD---DRDGTGLAAAAAAGPFPAPLNGSSQMPGNPPRLPFNDPFFVVETLCI
:::::: ::: : :.:.. : . :.. : :.::::.::::::
XP_011 CLETLPIFRDENEDMHGSGVT-------FHTYSNST---IGYQQSTSFTDPFFIVETLCI
190 200 210 220 230
220 230 240 250 260 270
pF1KE4 CWFSFELLVRLLVCPSKAIFFKNVMNLIDFVAILPYFVALGTELARQ---RGVGQQAMSL
:::::.:::...::::: :: :.::.::.:::.:::..::::::.. :::::::
XP_011 IWFSFEFLVRFFACPSKAGFFTNIMNIIDIVAIIPYFITLGTELAEKPEDAQQGQQAMSL
240 250 260 270 280 290
280 290 300 310 320 330
pF1KE4 AILRVIRLVRVFRIFKLSRHSKGLQILGQTLRASMRELGLLIFFLFIGVVLFSSAVYFAE
:::::::::::::::::::::::::::::::.:::::::::::::::::.::::::::::
XP_011 AILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAE
300 310 320 330 340 350
340 350 360 370 380 390
pF1KE4 VDRVDSHFTSIPESFWWAVVTMTTVGYGDMAPVTVGGKIVGSLCAIAGVLTISLPVPVIV
.:. .:.: :::..::::::.:::::::::.:.:.:::::::::::::::::.:::::::
XP_011 ADERESQFPSIPDAFWWAVVSMTTVGYGDMVPTTIGGKIVGSLCAIAGVLTIALPVPVIV
360 370 380 390 400 410
400 410 420 430 440 450
pF1KE4 SNFSYFYHRETEGEEAGMFSHVDMQPCGPLEGKANGGLVDGEVPELPPPLWAPPGKHLVT
:::.::::::::::: ... .: : :
XP_011 SNFNYFYHRETEGEEQAQYLQVTSCPKIPSSPDLKKSRSASTISKSDYMEIQEGVNNSNE
420 430 440 450 460 470
>>XP_011539699 (OMIM: 176262,616366) PREDICTED: potassiu (499 aa)
initn: 1928 init1: 839 opt: 1884 Z-score: 1961.7 bits: 372.3 E(85289): 1.6e-102
Smith-Waterman score: 1884; 68.0% identity (83.8% similar) in 419 aa overlap (11-423:31-439)
10 20 30 40
pF1KE4 MEPRCPPPCGCCERLVLNVAGLRFETRARTLGRFPDTLLG
::::.:.:..::::::. .::..::.::::
XP_011 MTVATGDPADEAAALPGHPQDTYDPEADHECCERVVINISGLRFETQLKTLAQFPETLLG
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE4 DPARRGRFYDDARREYFFDRHRPSFDAVLYYYQSGGRLRRPAHVPLDVFLEEVAFYGLGA
:: .: :..: : ::::::.::::::.:::::::::::::..::::.: ::. :: ::
XP_011 DPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDIFSEEIRFYELGE
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE4 AALARLREDEGCPVPPERPLPRRAFARQLWLLFEFPESSQAARVLAVVSVLVILVSIVVF
:. .::::: :::::. : ::.:::::.:::: ::..:.:::.:::.::: :
XP_011 EAMEMFREDEGYIKEEERPLPENEFQRQVWLLFEYPESSGPARIIAIVSVMVILISIVSF
130 140 150 160 170 180
170 180 190 200 210
pF1KE4 CLETLPDFRD---DRDGTGLAAAAAAGPFPAPLNGSSQMPGNPPRLPFNDPFFVVETLCI
:::::: ::: : :.:.. : . :.. : :.::::.::::::
XP_011 CLETLPIFRDENEDMHGSGVT-------FHTYSNST---IGYQQSTSFTDPFFIVETLCI
190 200 210 220 230
220 230 240 250 260 270
pF1KE4 CWFSFELLVRLLVCPSKAIFFKNVMNLIDFVAILPYFVALGTELARQ---RGVGQQAMSL
:::::.:::...::::: :: :.::.::.:::.:::..::::::.. :::::::
XP_011 IWFSFEFLVRFFACPSKAGFFTNIMNIIDIVAIIPYFITLGTELAEKPEDAQQGQQAMSL
240 250 260 270 280 290
280 290 300 310 320 330
pF1KE4 AILRVIRLVRVFRIFKLSRHSKGLQILGQTLRASMRELGLLIFFLFIGVVLFSSAVYFAE
:::::::::::::::::::::::::::::::.:::::::::::::::::.::::::::::
XP_011 AILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAE
300 310 320 330 340 350
340 350 360 370 380 390
pF1KE4 VDRVDSHFTSIPESFWWAVVTMTTVGYGDMAPVTVGGKIVGSLCAIAGVLTISLPVPVIV
.:. .:.: :::..::::::.:::::::::.:.:.:::::::::::::::::.:::::::
XP_011 ADERESQFPSIPDAFWWAVVSMTTVGYGDMVPTTIGGKIVGSLCAIAGVLTIALPVPVIV
360 370 380 390 400 410
400 410 420 430 440 450
pF1KE4 SNFSYFYHRETEGEEAGMFSHVDMQPCGPLEGKANGGLVDGEVPELPPPLWAPPGKHLVT
:::.::::::::::: ... .: : :
XP_011 SNFNYFYHRETEGEEQAQYLQVTSCPKIPSSPDLKKSRSASTISKSDYMEIQEGVNNSNE
420 430 440 450 460 470
>>XP_011539698 (OMIM: 176262,616366) PREDICTED: potassiu (499 aa)
initn: 1928 init1: 839 opt: 1884 Z-score: 1961.7 bits: 372.3 E(85289): 1.6e-102
Smith-Waterman score: 1884; 68.0% identity (83.8% similar) in 419 aa overlap (11-423:31-439)
10 20 30 40
pF1KE4 MEPRCPPPCGCCERLVLNVAGLRFETRARTLGRFPDTLLG
::::.:.:..::::::. .::..::.::::
XP_011 MTVATGDPADEAAALPGHPQDTYDPEADHECCERVVINISGLRFETQLKTLAQFPETLLG
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE4 DPARRGRFYDDARREYFFDRHRPSFDAVLYYYQSGGRLRRPAHVPLDVFLEEVAFYGLGA
:: .: :..: : ::::::.::::::.:::::::::::::..::::.: ::. :: ::
XP_011 DPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDIFSEEIRFYELGE
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE4 AALARLREDEGCPVPPERPLPRRAFARQLWLLFEFPESSQAARVLAVVSVLVILVSIVVF
:. .::::: :::::. : ::.:::::.:::: ::..:.:::.:::.::: :
XP_011 EAMEMFREDEGYIKEEERPLPENEFQRQVWLLFEYPESSGPARIIAIVSVMVILISIVSF
130 140 150 160 170 180
170 180 190 200 210
pF1KE4 CLETLPDFRD---DRDGTGLAAAAAAGPFPAPLNGSSQMPGNPPRLPFNDPFFVVETLCI
:::::: ::: : :.:.. : . :.. : :.::::.::::::
XP_011 CLETLPIFRDENEDMHGSGVT-------FHTYSNST---IGYQQSTSFTDPFFIVETLCI
190 200 210 220 230
220 230 240 250 260 270
pF1KE4 CWFSFELLVRLLVCPSKAIFFKNVMNLIDFVAILPYFVALGTELARQ---RGVGQQAMSL
:::::.:::...::::: :: :.::.::.:::.:::..::::::.. :::::::
XP_011 IWFSFEFLVRFFACPSKAGFFTNIMNIIDIVAIIPYFITLGTELAEKPEDAQQGQQAMSL
240 250 260 270 280 290
280 290 300 310 320 330
pF1KE4 AILRVIRLVRVFRIFKLSRHSKGLQILGQTLRASMRELGLLIFFLFIGVVLFSSAVYFAE
:::::::::::::::::::::::::::::::.:::::::::::::::::.::::::::::
XP_011 AILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAE
300 310 320 330 340 350
340 350 360 370 380 390
pF1KE4 VDRVDSHFTSIPESFWWAVVTMTTVGYGDMAPVTVGGKIVGSLCAIAGVLTISLPVPVIV
.:. .:.: :::..::::::.:::::::::.:.:.:::::::::::::::::.:::::::
XP_011 ADERESQFPSIPDAFWWAVVSMTTVGYGDMVPTTIGGKIVGSLCAIAGVLTIALPVPVIV
360 370 380 390 400 410
400 410 420 430 440 450
pF1KE4 SNFSYFYHRETEGEEAGMFSHVDMQPCGPLEGKANGGLVDGEVPELPPPLWAPPGKHLVT
:::.::::::::::: ... .: : :
XP_011 SNFNYFYHRETEGEEQAQYLQVTSCPKIPSSPDLKKSRSASTISKSDYMEIQEGVNNSNE
420 430 440 450 460 470
>>XP_011539701 (OMIM: 176262,616366) PREDICTED: potassiu (499 aa)
initn: 1928 init1: 839 opt: 1884 Z-score: 1961.7 bits: 372.3 E(85289): 1.6e-102
Smith-Waterman score: 1884; 68.0% identity (83.8% similar) in 419 aa overlap (11-423:31-439)
10 20 30 40
pF1KE4 MEPRCPPPCGCCERLVLNVAGLRFETRARTLGRFPDTLLG
::::.:.:..::::::. .::..::.::::
XP_011 MTVATGDPADEAAALPGHPQDTYDPEADHECCERVVINISGLRFETQLKTLAQFPETLLG
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE4 DPARRGRFYDDARREYFFDRHRPSFDAVLYYYQSGGRLRRPAHVPLDVFLEEVAFYGLGA
:: .: :..: : ::::::.::::::.:::::::::::::..::::.: ::. :: ::
XP_011 DPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDIFSEEIRFYELGE
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE4 AALARLREDEGCPVPPERPLPRRAFARQLWLLFEFPESSQAARVLAVVSVLVILVSIVVF
:. .::::: :::::. : ::.:::::.:::: ::..:.:::.:::.::: :
XP_011 EAMEMFREDEGYIKEEERPLPENEFQRQVWLLFEYPESSGPARIIAIVSVMVILISIVSF
130 140 150 160 170 180
170 180 190 200 210
pF1KE4 CLETLPDFRD---DRDGTGLAAAAAAGPFPAPLNGSSQMPGNPPRLPFNDPFFVVETLCI
:::::: ::: : :.:.. : . :.. : :.::::.::::::
XP_011 CLETLPIFRDENEDMHGSGVT-------FHTYSNST---IGYQQSTSFTDPFFIVETLCI
190 200 210 220 230
220 230 240 250 260 270
pF1KE4 CWFSFELLVRLLVCPSKAIFFKNVMNLIDFVAILPYFVALGTELARQ---RGVGQQAMSL
:::::.:::...::::: :: :.::.::.:::.:::..::::::.. :::::::
XP_011 IWFSFEFLVRFFACPSKAGFFTNIMNIIDIVAIIPYFITLGTELAEKPEDAQQGQQAMSL
240 250 260 270 280 290
280 290 300 310 320 330
pF1KE4 AILRVIRLVRVFRIFKLSRHSKGLQILGQTLRASMRELGLLIFFLFIGVVLFSSAVYFAE
:::::::::::::::::::::::::::::::.:::::::::::::::::.::::::::::
XP_011 AILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAE
300 310 320 330 340 350
340 350 360 370 380 390
pF1KE4 VDRVDSHFTSIPESFWWAVVTMTTVGYGDMAPVTVGGKIVGSLCAIAGVLTISLPVPVIV
.:. .:.: :::..::::::.:::::::::.:.:.:::::::::::::::::.:::::::
XP_011 ADERESQFPSIPDAFWWAVVSMTTVGYGDMVPTTIGGKIVGSLCAIAGVLTIALPVPVIV
360 370 380 390 400 410
400 410 420 430 440 450
pF1KE4 SNFSYFYHRETEGEEAGMFSHVDMQPCGPLEGKANGGLVDGEVPELPPPLWAPPGKHLVT
:::.::::::::::: ... .: : :
XP_011 SNFNYFYHRETEGEEQAQYLQVTSCPKIPSSPDLKKSRSASTISKSDYMEIQEGVNNSNE
420 430 440 450 460 470
>>XP_011539700 (OMIM: 176262,616366) PREDICTED: potassiu (499 aa)
initn: 1928 init1: 839 opt: 1884 Z-score: 1961.7 bits: 372.3 E(85289): 1.6e-102
Smith-Waterman score: 1884; 68.0% identity (83.8% similar) in 419 aa overlap (11-423:31-439)
10 20 30 40
pF1KE4 MEPRCPPPCGCCERLVLNVAGLRFETRARTLGRFPDTLLG
::::.:.:..::::::. .::..::.::::
XP_011 MTVATGDPADEAAALPGHPQDTYDPEADHECCERVVINISGLRFETQLKTLAQFPETLLG
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE4 DPARRGRFYDDARREYFFDRHRPSFDAVLYYYQSGGRLRRPAHVPLDVFLEEVAFYGLGA
:: .: :..: : ::::::.::::::.:::::::::::::..::::.: ::. :: ::
XP_011 DPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDIFSEEIRFYELGE
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE4 AALARLREDEGCPVPPERPLPRRAFARQLWLLFEFPESSQAARVLAVVSVLVILVSIVVF
:. .::::: :::::. : ::.:::::.:::: ::..:.:::.:::.::: :
XP_011 EAMEMFREDEGYIKEEERPLPENEFQRQVWLLFEYPESSGPARIIAIVSVMVILISIVSF
130 140 150 160 170 180
170 180 190 200 210
pF1KE4 CLETLPDFRD---DRDGTGLAAAAAAGPFPAPLNGSSQMPGNPPRLPFNDPFFVVETLCI
:::::: ::: : :.:.. : . :.. : :.::::.::::::
XP_011 CLETLPIFRDENEDMHGSGVT-------FHTYSNST---IGYQQSTSFTDPFFIVETLCI
190 200 210 220 230
220 230 240 250 260 270
pF1KE4 CWFSFELLVRLLVCPSKAIFFKNVMNLIDFVAILPYFVALGTELARQ---RGVGQQAMSL
:::::.:::...::::: :: :.::.::.:::.:::..::::::.. :::::::
XP_011 IWFSFEFLVRFFACPSKAGFFTNIMNIIDIVAIIPYFITLGTELAEKPEDAQQGQQAMSL
240 250 260 270 280 290
280 290 300 310 320 330
pF1KE4 AILRVIRLVRVFRIFKLSRHSKGLQILGQTLRASMRELGLLIFFLFIGVVLFSSAVYFAE
:::::::::::::::::::::::::::::::.:::::::::::::::::.::::::::::
XP_011 AILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAE
300 310 320 330 340 350
340 350 360 370 380 390
pF1KE4 VDRVDSHFTSIPESFWWAVVTMTTVGYGDMAPVTVGGKIVGSLCAIAGVLTISLPVPVIV
.:. .:.: :::..::::::.:::::::::.:.:.:::::::::::::::::.:::::::
XP_011 ADERESQFPSIPDAFWWAVVSMTTVGYGDMVPTTIGGKIVGSLCAIAGVLTIALPVPVIV
360 370 380 390 400 410
400 410 420 430 440 450
pF1KE4 SNFSYFYHRETEGEEAGMFSHVDMQPCGPLEGKANGGLVDGEVPELPPPLWAPPGKHLVT
:::.::::::::::: ... .: : :
XP_011 SNFNYFYHRETEGEEQAQYLQVTSCPKIPSSPDLKKSRSASTISKSDYMEIQEGVNNSNE
420 430 440 450 460 470
>>NP_004965 (OMIM: 176262,616366) potassium voltage-gate (499 aa)
initn: 1928 init1: 839 opt: 1884 Z-score: 1961.7 bits: 372.3 E(85289): 1.6e-102
Smith-Waterman score: 1884; 68.0% identity (83.8% similar) in 419 aa overlap (11-423:31-439)
10 20 30 40
pF1KE4 MEPRCPPPCGCCERLVLNVAGLRFETRARTLGRFPDTLLG
::::.:.:..::::::. .::..::.::::
NP_004 MTVATGDPADEAAALPGHPQDTYDPEADHECCERVVINISGLRFETQLKTLAQFPETLLG
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE4 DPARRGRFYDDARREYFFDRHRPSFDAVLYYYQSGGRLRRPAHVPLDVFLEEVAFYGLGA
:: .: :..: : ::::::.::::::.:::::::::::::..::::.: ::. :: ::
NP_004 DPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDIFSEEIRFYELGE
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE4 AALARLREDEGCPVPPERPLPRRAFARQLWLLFEFPESSQAARVLAVVSVLVILVSIVVF
:. .::::: :::::. : ::.:::::.:::: ::..:.:::.:::.::: :
NP_004 EAMEMFREDEGYIKEEERPLPENEFQRQVWLLFEYPESSGPARIIAIVSVMVILISIVSF
130 140 150 160 170 180
170 180 190 200 210
pF1KE4 CLETLPDFRD---DRDGTGLAAAAAAGPFPAPLNGSSQMPGNPPRLPFNDPFFVVETLCI
:::::: ::: : :.:.. : . :.. : :.::::.::::::
NP_004 CLETLPIFRDENEDMHGSGVT-------FHTYSNST---IGYQQSTSFTDPFFIVETLCI
190 200 210 220 230
220 230 240 250 260 270
pF1KE4 CWFSFELLVRLLVCPSKAIFFKNVMNLIDFVAILPYFVALGTELARQ---RGVGQQAMSL
:::::.:::...::::: :: :.::.::.:::.:::..::::::.. :::::::
NP_004 IWFSFEFLVRFFACPSKAGFFTNIMNIIDIVAIIPYFITLGTELAEKPEDAQQGQQAMSL
240 250 260 270 280 290
280 290 300 310 320 330
pF1KE4 AILRVIRLVRVFRIFKLSRHSKGLQILGQTLRASMRELGLLIFFLFIGVVLFSSAVYFAE
:::::::::::::::::::::::::::::::.:::::::::::::::::.::::::::::
NP_004 AILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAE
300 310 320 330 340 350
340 350 360 370 380 390
pF1KE4 VDRVDSHFTSIPESFWWAVVTMTTVGYGDMAPVTVGGKIVGSLCAIAGVLTISLPVPVIV
.:. .:.: :::..::::::.:::::::::.:.:.:::::::::::::::::.:::::::
NP_004 ADERESQFPSIPDAFWWAVVSMTTVGYGDMVPTTIGGKIVGSLCAIAGVLTIALPVPVIV
360 370 380 390 400 410
400 410 420 430 440 450
pF1KE4 SNFSYFYHRETEGEEAGMFSHVDMQPCGPLEGKANGGLVDGEVPELPPPLWAPPGKHLVT
:::.::::::::::: ... .: : :
NP_004 SNFNYFYHRETEGEEQAQYLQVTSCPKIPSSPDLKKSRSASTISKSDYMEIQEGVNNSNE
420 430 440 450 460 470
456 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 14:34:48 2016 done: Mon Nov 7 14:34:50 2016
Total Scan time: 10.570 Total Display time: 0.070
Function used was FASTA [36.3.4 Apr, 2011]