Result of FASTA (omim) for
pFN21AE4085
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE4085, 446 aa
1>>>pF1KE4085 446 - 446 aa - 446 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.4176+/-0.000287; mu= 9.3256+/- 0.018
mean_var=154.3855+/-32.690, 0's: 0 Z-trim(122.8): 197 B-trim: 1857 in 1/57
Lambda= 0.103222
statistics sampled from 41340 (41584) to 41340 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.798), E-opt: 0.2 (0.488), width: 16
Scan time: 11.270
The best scores are: opt bits E(85289)
XP_006718602 (OMIM: 610831) PREDICTED: carabin iso ( 446) 3119 475.8 9.9e-134
NP_940919 (OMIM: 610831) carabin isoform 1 [Homo s ( 446) 3119 475.8 9.9e-134
XP_006718603 (OMIM: 610831) PREDICTED: carabin iso ( 446) 3119 475.8 9.9e-134
XP_006718601 (OMIM: 610831) PREDICTED: carabin iso ( 446) 3119 475.8 9.9e-134
XP_011543304 (OMIM: 610831) PREDICTED: carabin iso ( 313) 2028 313.2 6.1e-85
XP_006718604 (OMIM: 610831) PREDICTED: carabin iso ( 345) 1992 307.9 2.7e-83
XP_006718605 (OMIM: 610831) PREDICTED: carabin iso ( 345) 1992 307.9 2.7e-83
XP_011543303 (OMIM: 610831) PREDICTED: carabin iso ( 345) 1992 307.9 2.7e-83
XP_006718606 (OMIM: 610831) PREDICTED: carabin iso ( 345) 1992 307.9 2.7e-83
XP_006718607 (OMIM: 610831) PREDICTED: carabin iso ( 345) 1992 307.9 2.7e-83
NP_114143 (OMIM: 610020) TBC1 domain family member ( 508) 1384 217.5 6.5e-56
NP_001191169 (OMIM: 610020) TBC1 domain family mem ( 515) 1368 215.1 3.4e-55
NP_056342 (OMIM: 613620) TBC1 domain family member ( 808) 1368 215.3 4.9e-55
NP_001243437 (OMIM: 610831) carabin isoform 2 [Hom ( 310) 1129 179.3 1.2e-44
XP_011544092 (OMIM: 613620) PREDICTED: TBC1 domain ( 536) 881 142.6 2.4e-33
XP_011544091 (OMIM: 613620) PREDICTED: TBC1 domain ( 703) 820 133.6 1.6e-30
XP_016858483 (OMIM: 609238) PREDICTED: rab GTPase- ( 778) 523 89.4 3.6e-17
NP_055672 (OMIM: 609238) rab GTPase-activating pro ( 815) 523 89.4 3.7e-17
XP_006711756 (OMIM: 609238) PREDICTED: rab GTPase- ( 985) 523 89.5 4.3e-17
XP_005245738 (OMIM: 609238) PREDICTED: rab GTPase- (1014) 523 89.5 4.4e-17
XP_011508525 (OMIM: 609238) PREDICTED: rab GTPase- (1051) 523 89.5 4.5e-17
XP_005245737 (OMIM: 609238) PREDICTED: rab GTPase- (1051) 523 89.5 4.5e-17
XP_016857774 (OMIM: 602942) PREDICTED: ecotropic v ( 741) 505 86.7 2.2e-16
XP_016857773 (OMIM: 602942) PREDICTED: ecotropic v ( 777) 505 86.7 2.3e-16
XP_016857772 (OMIM: 602942) PREDICTED: ecotropic v ( 785) 505 86.7 2.3e-16
NP_005656 (OMIM: 602942) ecotropic viral integrati ( 810) 505 86.7 2.4e-16
XP_016857770 (OMIM: 602942) PREDICTED: ecotropic v ( 818) 505 86.8 2.4e-16
NP_001295177 (OMIM: 602942) ecotropic viral integr ( 821) 505 86.8 2.4e-16
XP_016857769 (OMIM: 602942) PREDICTED: ecotropic v ( 826) 505 86.8 2.4e-16
XP_016857766 (OMIM: 602942) PREDICTED: ecotropic v ( 854) 505 86.8 2.5e-16
XP_016857765 (OMIM: 602942) PREDICTED: ecotropic v ( 859) 505 86.8 2.5e-16
XP_016857760 (OMIM: 602942) PREDICTED: ecotropic v ( 903) 505 86.8 2.6e-16
XP_011516744 (OMIM: 615882) PREDICTED: rab GTPase- ( 900) 468 81.3 1.2e-14
XP_016870059 (OMIM: 615882) PREDICTED: rab GTPase- ( 900) 468 81.3 1.2e-14
XP_011516742 (OMIM: 615882) PREDICTED: rab GTPase- (1069) 468 81.3 1.3e-14
XP_011516743 (OMIM: 615882) PREDICTED: rab GTPase- (1069) 468 81.3 1.3e-14
NP_036329 (OMIM: 615882) rab GTPase-activating pro (1069) 468 81.3 1.3e-14
XP_016870056 (OMIM: 615882) PREDICTED: rab GTPase- (1069) 468 81.3 1.3e-14
XP_016870058 (OMIM: 615882) PREDICTED: rab GTPase- (1069) 468 81.3 1.3e-14
XP_016870057 (OMIM: 615882) PREDICTED: rab GTPase- (1069) 468 81.3 1.3e-14
NP_001254501 (OMIM: 609871) TBC1 domain family mem ( 468) 450 78.4 4.5e-14
XP_011517145 (OMIM: 609871) PREDICTED: TBC1 domain ( 468) 450 78.4 4.5e-14
XP_016870388 (OMIM: 609871) PREDICTED: TBC1 domain ( 483) 450 78.4 4.7e-14
NP_001254500 (OMIM: 609871) TBC1 domain family mem ( 928) 450 78.6 7.7e-14
NP_055503 (OMIM: 605405) USP6 N-terminal-like prot ( 828) 446 78.0 1.1e-13
NP_001073960 (OMIM: 605405) USP6 N-terminal-like p ( 845) 446 78.0 1.1e-13
XP_016872460 (OMIM: 605405) PREDICTED: USP6 N-term ( 846) 446 78.0 1.1e-13
XP_016872462 (OMIM: 605405) PREDICTED: USP6 N-term ( 851) 446 78.0 1.1e-13
XP_011518064 (OMIM: 605405) PREDICTED: USP6 N-term ( 856) 446 78.0 1.1e-13
XP_006717605 (OMIM: 605405) PREDICTED: USP6 N-term ( 856) 446 78.0 1.1e-13
>>XP_006718602 (OMIM: 610831) PREDICTED: carabin isoform (446 aa)
initn: 3119 init1: 3119 opt: 3119 Z-score: 2521.9 bits: 475.8 E(85289): 9.9e-134
Smith-Waterman score: 3119; 100.0% identity (100.0% similar) in 446 aa overlap (1-446:1-446)
10 20 30 40 50 60
pF1KE4 MAQALGEDLVQPPELQDDSSSLGSDSELSGPGPYRQADRYGFIGGSSAEPGPGHPPADLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MAQALGEDLVQPPELQDDSSSLGSDSELSGPGPYRQADRYGFIGGSSAEPGPGHPPADLI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 RQREMKWVEMTSHWEKTMSRRYKKVKMQCRKGIPSALRARCWPLLCGAHVCQKNSPGTYQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RQREMKWVEMTSHWEKTMSRRYKKVKMQCRKGIPSALRARCWPLLCGAHVCQKNSPGTYQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 ELAEAPGDPQWMETIGRDLHRQFPLHEMFVSPQGHGQQGLLQVLKAYTLYRPEQGYCQAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ELAEAPGDPQWMETIGRDLHRQFPLHEMFVSPQGHGQQGLLQVLKAYTLYRPEQGYCQAQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 GPVAAVLLMHLPPEEAFWCLVQICEVYLPGYYGPHMEAVRLDAEVFMALLRRLLPHVHKH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GPVAAVLLMHLPPEEAFWCLVQICEVYLPGYYGPHMEAVRLDAEVFMALLRRLLPHVHKH
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 LQQVGVGPLLYLPEWFLCLFARSLPFPTVLRVWDAFLSEGARVLFRVGLTLVRLALGTAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LQQVGVGPLLYLPEWFLCLFARSLPFPTVLRVWDAFLSEGARVLFRVGLTLVRLALGTAE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 QRGACPGLLETLGALRAIPPAQLQEEAFMSQVHSVVLSERDLQREIKAQLAQLPDSAPGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QRGACPGLLETLGALRAIPPAQLQEEAFMSQVHSVVLSERDLQREIKAQLAQLPDSAPGP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 PPRPQVRLAGAQAIFEAQQLAGVRRGAKPEVPRIVVQPPEEPRPPRRKPQTRGKTFHGLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PPRPQVRLAGAQAIFEAQQLAGVRRGAKPEVPRIVVQPPEEPRPPRRKPQTRGKTFHGLL
370 380 390 400 410 420
430 440
pF1KE4 TRARGPPIEGPPRPQRGSTSFLDTRF
::::::::::::::::::::::::::
XP_006 TRARGPPIEGPPRPQRGSTSFLDTRF
430 440
>>NP_940919 (OMIM: 610831) carabin isoform 1 [Homo sapie (446 aa)
initn: 3119 init1: 3119 opt: 3119 Z-score: 2521.9 bits: 475.8 E(85289): 9.9e-134
Smith-Waterman score: 3119; 100.0% identity (100.0% similar) in 446 aa overlap (1-446:1-446)
10 20 30 40 50 60
pF1KE4 MAQALGEDLVQPPELQDDSSSLGSDSELSGPGPYRQADRYGFIGGSSAEPGPGHPPADLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_940 MAQALGEDLVQPPELQDDSSSLGSDSELSGPGPYRQADRYGFIGGSSAEPGPGHPPADLI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 RQREMKWVEMTSHWEKTMSRRYKKVKMQCRKGIPSALRARCWPLLCGAHVCQKNSPGTYQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_940 RQREMKWVEMTSHWEKTMSRRYKKVKMQCRKGIPSALRARCWPLLCGAHVCQKNSPGTYQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 ELAEAPGDPQWMETIGRDLHRQFPLHEMFVSPQGHGQQGLLQVLKAYTLYRPEQGYCQAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_940 ELAEAPGDPQWMETIGRDLHRQFPLHEMFVSPQGHGQQGLLQVLKAYTLYRPEQGYCQAQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 GPVAAVLLMHLPPEEAFWCLVQICEVYLPGYYGPHMEAVRLDAEVFMALLRRLLPHVHKH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_940 GPVAAVLLMHLPPEEAFWCLVQICEVYLPGYYGPHMEAVRLDAEVFMALLRRLLPHVHKH
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 LQQVGVGPLLYLPEWFLCLFARSLPFPTVLRVWDAFLSEGARVLFRVGLTLVRLALGTAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_940 LQQVGVGPLLYLPEWFLCLFARSLPFPTVLRVWDAFLSEGARVLFRVGLTLVRLALGTAE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 QRGACPGLLETLGALRAIPPAQLQEEAFMSQVHSVVLSERDLQREIKAQLAQLPDSAPGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_940 QRGACPGLLETLGALRAIPPAQLQEEAFMSQVHSVVLSERDLQREIKAQLAQLPDSAPGP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 PPRPQVRLAGAQAIFEAQQLAGVRRGAKPEVPRIVVQPPEEPRPPRRKPQTRGKTFHGLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_940 PPRPQVRLAGAQAIFEAQQLAGVRRGAKPEVPRIVVQPPEEPRPPRRKPQTRGKTFHGLL
370 380 390 400 410 420
430 440
pF1KE4 TRARGPPIEGPPRPQRGSTSFLDTRF
::::::::::::::::::::::::::
NP_940 TRARGPPIEGPPRPQRGSTSFLDTRF
430 440
>>XP_006718603 (OMIM: 610831) PREDICTED: carabin isoform (446 aa)
initn: 3119 init1: 3119 opt: 3119 Z-score: 2521.9 bits: 475.8 E(85289): 9.9e-134
Smith-Waterman score: 3119; 100.0% identity (100.0% similar) in 446 aa overlap (1-446:1-446)
10 20 30 40 50 60
pF1KE4 MAQALGEDLVQPPELQDDSSSLGSDSELSGPGPYRQADRYGFIGGSSAEPGPGHPPADLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MAQALGEDLVQPPELQDDSSSLGSDSELSGPGPYRQADRYGFIGGSSAEPGPGHPPADLI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 RQREMKWVEMTSHWEKTMSRRYKKVKMQCRKGIPSALRARCWPLLCGAHVCQKNSPGTYQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RQREMKWVEMTSHWEKTMSRRYKKVKMQCRKGIPSALRARCWPLLCGAHVCQKNSPGTYQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 ELAEAPGDPQWMETIGRDLHRQFPLHEMFVSPQGHGQQGLLQVLKAYTLYRPEQGYCQAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ELAEAPGDPQWMETIGRDLHRQFPLHEMFVSPQGHGQQGLLQVLKAYTLYRPEQGYCQAQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 GPVAAVLLMHLPPEEAFWCLVQICEVYLPGYYGPHMEAVRLDAEVFMALLRRLLPHVHKH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GPVAAVLLMHLPPEEAFWCLVQICEVYLPGYYGPHMEAVRLDAEVFMALLRRLLPHVHKH
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 LQQVGVGPLLYLPEWFLCLFARSLPFPTVLRVWDAFLSEGARVLFRVGLTLVRLALGTAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LQQVGVGPLLYLPEWFLCLFARSLPFPTVLRVWDAFLSEGARVLFRVGLTLVRLALGTAE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 QRGACPGLLETLGALRAIPPAQLQEEAFMSQVHSVVLSERDLQREIKAQLAQLPDSAPGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QRGACPGLLETLGALRAIPPAQLQEEAFMSQVHSVVLSERDLQREIKAQLAQLPDSAPGP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 PPRPQVRLAGAQAIFEAQQLAGVRRGAKPEVPRIVVQPPEEPRPPRRKPQTRGKTFHGLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PPRPQVRLAGAQAIFEAQQLAGVRRGAKPEVPRIVVQPPEEPRPPRRKPQTRGKTFHGLL
370 380 390 400 410 420
430 440
pF1KE4 TRARGPPIEGPPRPQRGSTSFLDTRF
::::::::::::::::::::::::::
XP_006 TRARGPPIEGPPRPQRGSTSFLDTRF
430 440
>>XP_006718601 (OMIM: 610831) PREDICTED: carabin isoform (446 aa)
initn: 3119 init1: 3119 opt: 3119 Z-score: 2521.9 bits: 475.8 E(85289): 9.9e-134
Smith-Waterman score: 3119; 100.0% identity (100.0% similar) in 446 aa overlap (1-446:1-446)
10 20 30 40 50 60
pF1KE4 MAQALGEDLVQPPELQDDSSSLGSDSELSGPGPYRQADRYGFIGGSSAEPGPGHPPADLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MAQALGEDLVQPPELQDDSSSLGSDSELSGPGPYRQADRYGFIGGSSAEPGPGHPPADLI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 RQREMKWVEMTSHWEKTMSRRYKKVKMQCRKGIPSALRARCWPLLCGAHVCQKNSPGTYQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RQREMKWVEMTSHWEKTMSRRYKKVKMQCRKGIPSALRARCWPLLCGAHVCQKNSPGTYQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 ELAEAPGDPQWMETIGRDLHRQFPLHEMFVSPQGHGQQGLLQVLKAYTLYRPEQGYCQAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ELAEAPGDPQWMETIGRDLHRQFPLHEMFVSPQGHGQQGLLQVLKAYTLYRPEQGYCQAQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 GPVAAVLLMHLPPEEAFWCLVQICEVYLPGYYGPHMEAVRLDAEVFMALLRRLLPHVHKH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GPVAAVLLMHLPPEEAFWCLVQICEVYLPGYYGPHMEAVRLDAEVFMALLRRLLPHVHKH
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 LQQVGVGPLLYLPEWFLCLFARSLPFPTVLRVWDAFLSEGARVLFRVGLTLVRLALGTAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LQQVGVGPLLYLPEWFLCLFARSLPFPTVLRVWDAFLSEGARVLFRVGLTLVRLALGTAE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 QRGACPGLLETLGALRAIPPAQLQEEAFMSQVHSVVLSERDLQREIKAQLAQLPDSAPGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QRGACPGLLETLGALRAIPPAQLQEEAFMSQVHSVVLSERDLQREIKAQLAQLPDSAPGP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 PPRPQVRLAGAQAIFEAQQLAGVRRGAKPEVPRIVVQPPEEPRPPRRKPQTRGKTFHGLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PPRPQVRLAGAQAIFEAQQLAGVRRGAKPEVPRIVVQPPEEPRPPRRKPQTRGKTFHGLL
370 380 390 400 410 420
430 440
pF1KE4 TRARGPPIEGPPRPQRGSTSFLDTRF
::::::::::::::::::::::::::
XP_006 TRARGPPIEGPPRPQRGSTSFLDTRF
430 440
>>XP_011543304 (OMIM: 610831) PREDICTED: carabin isoform (313 aa)
initn: 2034 init1: 2005 opt: 2028 Z-score: 1646.0 bits: 313.2 E(85289): 6.1e-85
Smith-Waterman score: 2028; 94.8% identity (95.8% similar) in 306 aa overlap (1-306:1-298)
10 20 30 40 50 60
pF1KE4 MAQALGEDLVQPPELQDDSSSLGSDSELSGPGPYRQADRYGFIGGSSAEPGPGHPPADLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAQALGEDLVQPPELQDDSSSLGSDSELSGPGPYRQADRYGFIGGSSAEPGPGHPPADLI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 RQREMKWVEMTSHWEKTMSRRYKKVKMQCRKGIPSALRARCWPLLCGAHVCQKNSPGTYQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RQREMKWVEMTSHWEKTMSRRYKKVKMQCRKGIPSALRARCWPLLCGAHVCQKNSPGTYQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 ELAEAPGDPQWMETIGRDLHRQFPLHEMFVSPQGHGQQGLLQVLKAYTLYRPEQGYCQAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELAEAPGDPQWMETIGRDLHRQFPLHEMFVSPQGHGQQGLLQVLKAYTLYRPEQGYCQAQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 GPVAAVLLMHLPPEEAFWCLVQICEVYLPGYYGPHMEAVRLDAEVFMALLRRLLPHVHKH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GPVAAVLLMHLPPEEAFWCLVQICEVYLPGYYGPHMEAVRLDAEVFMALLRRLLPHVHKH
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 LQQVGVGPLLYLPEWFLCLFARSLPFPTVLRVWDAFLSEGARVLFRVGLTLVRLALGTAE
::::::::::::::::::::::::::::::::::::::::. ::: : :. .
XP_011 LQQVGVGPLLYLPEWFLCLFARSLPFPTVLRVWDAFLSEGG------GLTGV--AVEAWG
250 260 270 280 290
310 320 330 340 350 360
pF1KE4 QRGACPGLLETLGALRAIPPAQLQEEAFMSQVHSVVLSERDLQREIKAQLAQLPDSAPGP
::: ::
XP_011 QRGHCPQGPGYSLRSREGLEP
300 310
>>XP_006718604 (OMIM: 610831) PREDICTED: carabin isoform (345 aa)
initn: 1985 init1: 1985 opt: 1992 Z-score: 1616.4 bits: 307.9 E(85289): 2.7e-83
Smith-Waterman score: 1992; 91.7% identity (92.9% similar) in 324 aa overlap (127-446:23-345)
100 110 120 130 140 150
pF1KE4 LRARCWPLLCGAHVCQKNSPGTYQELAEAPGDPQWMETIGRDLHRQFPLHEMF----VSP
: : :. : : : : . :
XP_006 MLAPVVWGPCVPEEQPWHLSGAGRGPWRPTVDGD-HWQGPAPSIPSARDVCV
10 20 30 40 50
160 170 180 190 200 210
pF1KE4 QGHGQQGLLQVLKAYTLYRPEQGYCQAQGPVAAVLLMHLPPEEAFWCLVQICEVYLPGYY
. .:::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ASGPRQGLLQVLKAYTLYRPEQGYCQAQGPVAAVLLMHLPPEEAFWCLVQICEVYLPGYY
60 70 80 90 100 110
220 230 240 250 260 270
pF1KE4 GPHMEAVRLDAEVFMALLRRLLPHVHKHLQQVGVGPLLYLPEWFLCLFARSLPFPTVLRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GPHMEAVRLDAEVFMALLRRLLPHVHKHLQQVGVGPLLYLPEWFLCLFARSLPFPTVLRV
120 130 140 150 160 170
280 290 300 310 320 330
pF1KE4 WDAFLSEGARVLFRVGLTLVRLALGTAEQRGACPGLLETLGALRAIPPAQLQEEAFMSQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 WDAFLSEGARVLFRVGLTLVRLALGTAEQRGACPGLLETLGALRAIPPAQLQEEAFMSQV
180 190 200 210 220 230
340 350 360 370 380 390
pF1KE4 HSVVLSERDLQREIKAQLAQLPDSAPGPPPRPQVRLAGAQAIFEAQQLAGVRRGAKPEVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HSVVLSERDLQREIKAQLAQLPDSAPGPPPRPQVRLAGAQAIFEAQQLAGVRRGAKPEVP
240 250 260 270 280 290
400 410 420 430 440
pF1KE4 RIVVQPPEEPRPPRRKPQTRGKTFHGLLTRARGPPIEGPPRPQRGSTSFLDTRF
::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RIVVQPPEEPRPPRRKPQTRGKTFHGLLTRARGPPIEGPPRPQRGSTSFLDTRF
300 310 320 330 340
>>XP_006718605 (OMIM: 610831) PREDICTED: carabin isoform (345 aa)
initn: 1985 init1: 1985 opt: 1992 Z-score: 1616.4 bits: 307.9 E(85289): 2.7e-83
Smith-Waterman score: 1992; 91.7% identity (92.9% similar) in 324 aa overlap (127-446:23-345)
100 110 120 130 140 150
pF1KE4 LRARCWPLLCGAHVCQKNSPGTYQELAEAPGDPQWMETIGRDLHRQFPLHEMF----VSP
: : :. : : : : . :
XP_006 MLAPVVWGPCVPEEQPWHLSGAGRGPWRPTVDGD-HWQGPAPSIPSARDVCV
10 20 30 40 50
160 170 180 190 200 210
pF1KE4 QGHGQQGLLQVLKAYTLYRPEQGYCQAQGPVAAVLLMHLPPEEAFWCLVQICEVYLPGYY
. .:::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ASGPRQGLLQVLKAYTLYRPEQGYCQAQGPVAAVLLMHLPPEEAFWCLVQICEVYLPGYY
60 70 80 90 100 110
220 230 240 250 260 270
pF1KE4 GPHMEAVRLDAEVFMALLRRLLPHVHKHLQQVGVGPLLYLPEWFLCLFARSLPFPTVLRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GPHMEAVRLDAEVFMALLRRLLPHVHKHLQQVGVGPLLYLPEWFLCLFARSLPFPTVLRV
120 130 140 150 160 170
280 290 300 310 320 330
pF1KE4 WDAFLSEGARVLFRVGLTLVRLALGTAEQRGACPGLLETLGALRAIPPAQLQEEAFMSQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 WDAFLSEGARVLFRVGLTLVRLALGTAEQRGACPGLLETLGALRAIPPAQLQEEAFMSQV
180 190 200 210 220 230
340 350 360 370 380 390
pF1KE4 HSVVLSERDLQREIKAQLAQLPDSAPGPPPRPQVRLAGAQAIFEAQQLAGVRRGAKPEVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HSVVLSERDLQREIKAQLAQLPDSAPGPPPRPQVRLAGAQAIFEAQQLAGVRRGAKPEVP
240 250 260 270 280 290
400 410 420 430 440
pF1KE4 RIVVQPPEEPRPPRRKPQTRGKTFHGLLTRARGPPIEGPPRPQRGSTSFLDTRF
::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RIVVQPPEEPRPPRRKPQTRGKTFHGLLTRARGPPIEGPPRPQRGSTSFLDTRF
300 310 320 330 340
>>XP_011543303 (OMIM: 610831) PREDICTED: carabin isoform (345 aa)
initn: 1985 init1: 1985 opt: 1992 Z-score: 1616.4 bits: 307.9 E(85289): 2.7e-83
Smith-Waterman score: 1992; 91.7% identity (92.9% similar) in 324 aa overlap (127-446:23-345)
100 110 120 130 140 150
pF1KE4 LRARCWPLLCGAHVCQKNSPGTYQELAEAPGDPQWMETIGRDLHRQFPLHEMF----VSP
: : :. : : : : . :
XP_011 MLAPVVWGPCVPEEQPWHLSGAGRGPWRPTVDGD-HWQGPAPSIPSARDVCV
10 20 30 40 50
160 170 180 190 200 210
pF1KE4 QGHGQQGLLQVLKAYTLYRPEQGYCQAQGPVAAVLLMHLPPEEAFWCLVQICEVYLPGYY
. .:::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ASGPRQGLLQVLKAYTLYRPEQGYCQAQGPVAAVLLMHLPPEEAFWCLVQICEVYLPGYY
60 70 80 90 100 110
220 230 240 250 260 270
pF1KE4 GPHMEAVRLDAEVFMALLRRLLPHVHKHLQQVGVGPLLYLPEWFLCLFARSLPFPTVLRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GPHMEAVRLDAEVFMALLRRLLPHVHKHLQQVGVGPLLYLPEWFLCLFARSLPFPTVLRV
120 130 140 150 160 170
280 290 300 310 320 330
pF1KE4 WDAFLSEGARVLFRVGLTLVRLALGTAEQRGACPGLLETLGALRAIPPAQLQEEAFMSQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WDAFLSEGARVLFRVGLTLVRLALGTAEQRGACPGLLETLGALRAIPPAQLQEEAFMSQV
180 190 200 210 220 230
340 350 360 370 380 390
pF1KE4 HSVVLSERDLQREIKAQLAQLPDSAPGPPPRPQVRLAGAQAIFEAQQLAGVRRGAKPEVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HSVVLSERDLQREIKAQLAQLPDSAPGPPPRPQVRLAGAQAIFEAQQLAGVRRGAKPEVP
240 250 260 270 280 290
400 410 420 430 440
pF1KE4 RIVVQPPEEPRPPRRKPQTRGKTFHGLLTRARGPPIEGPPRPQRGSTSFLDTRF
::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RIVVQPPEEPRPPRRKPQTRGKTFHGLLTRARGPPIEGPPRPQRGSTSFLDTRF
300 310 320 330 340
>>XP_006718606 (OMIM: 610831) PREDICTED: carabin isoform (345 aa)
initn: 1985 init1: 1985 opt: 1992 Z-score: 1616.4 bits: 307.9 E(85289): 2.7e-83
Smith-Waterman score: 1992; 91.7% identity (92.9% similar) in 324 aa overlap (127-446:23-345)
100 110 120 130 140 150
pF1KE4 LRARCWPLLCGAHVCQKNSPGTYQELAEAPGDPQWMETIGRDLHRQFPLHEMF----VSP
: : :. : : : : . :
XP_006 MLAPVVWGPCVPEEQPWHLSGAGRGPWRPTVDGD-HWQGPAPSIPSARDVCV
10 20 30 40 50
160 170 180 190 200 210
pF1KE4 QGHGQQGLLQVLKAYTLYRPEQGYCQAQGPVAAVLLMHLPPEEAFWCLVQICEVYLPGYY
. .:::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ASGPRQGLLQVLKAYTLYRPEQGYCQAQGPVAAVLLMHLPPEEAFWCLVQICEVYLPGYY
60 70 80 90 100 110
220 230 240 250 260 270
pF1KE4 GPHMEAVRLDAEVFMALLRRLLPHVHKHLQQVGVGPLLYLPEWFLCLFARSLPFPTVLRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GPHMEAVRLDAEVFMALLRRLLPHVHKHLQQVGVGPLLYLPEWFLCLFARSLPFPTVLRV
120 130 140 150 160 170
280 290 300 310 320 330
pF1KE4 WDAFLSEGARVLFRVGLTLVRLALGTAEQRGACPGLLETLGALRAIPPAQLQEEAFMSQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 WDAFLSEGARVLFRVGLTLVRLALGTAEQRGACPGLLETLGALRAIPPAQLQEEAFMSQV
180 190 200 210 220 230
340 350 360 370 380 390
pF1KE4 HSVVLSERDLQREIKAQLAQLPDSAPGPPPRPQVRLAGAQAIFEAQQLAGVRRGAKPEVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HSVVLSERDLQREIKAQLAQLPDSAPGPPPRPQVRLAGAQAIFEAQQLAGVRRGAKPEVP
240 250 260 270 280 290
400 410 420 430 440
pF1KE4 RIVVQPPEEPRPPRRKPQTRGKTFHGLLTRARGPPIEGPPRPQRGSTSFLDTRF
::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RIVVQPPEEPRPPRRKPQTRGKTFHGLLTRARGPPIEGPPRPQRGSTSFLDTRF
300 310 320 330 340
>>XP_006718607 (OMIM: 610831) PREDICTED: carabin isoform (345 aa)
initn: 1985 init1: 1985 opt: 1992 Z-score: 1616.4 bits: 307.9 E(85289): 2.7e-83
Smith-Waterman score: 1992; 91.7% identity (92.9% similar) in 324 aa overlap (127-446:23-345)
100 110 120 130 140 150
pF1KE4 LRARCWPLLCGAHVCQKNSPGTYQELAEAPGDPQWMETIGRDLHRQFPLHEMF----VSP
: : :. : : : : . :
XP_006 MLAPVVWGPCVPEEQPWHLSGAGRGPWRPTVDGD-HWQGPAPSIPSARDVCV
10 20 30 40 50
160 170 180 190 200 210
pF1KE4 QGHGQQGLLQVLKAYTLYRPEQGYCQAQGPVAAVLLMHLPPEEAFWCLVQICEVYLPGYY
. .:::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ASGPRQGLLQVLKAYTLYRPEQGYCQAQGPVAAVLLMHLPPEEAFWCLVQICEVYLPGYY
60 70 80 90 100 110
220 230 240 250 260 270
pF1KE4 GPHMEAVRLDAEVFMALLRRLLPHVHKHLQQVGVGPLLYLPEWFLCLFARSLPFPTVLRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GPHMEAVRLDAEVFMALLRRLLPHVHKHLQQVGVGPLLYLPEWFLCLFARSLPFPTVLRV
120 130 140 150 160 170
280 290 300 310 320 330
pF1KE4 WDAFLSEGARVLFRVGLTLVRLALGTAEQRGACPGLLETLGALRAIPPAQLQEEAFMSQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 WDAFLSEGARVLFRVGLTLVRLALGTAEQRGACPGLLETLGALRAIPPAQLQEEAFMSQV
180 190 200 210 220 230
340 350 360 370 380 390
pF1KE4 HSVVLSERDLQREIKAQLAQLPDSAPGPPPRPQVRLAGAQAIFEAQQLAGVRRGAKPEVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HSVVLSERDLQREIKAQLAQLPDSAPGPPPRPQVRLAGAQAIFEAQQLAGVRRGAKPEVP
240 250 260 270 280 290
400 410 420 430 440
pF1KE4 RIVVQPPEEPRPPRRKPQTRGKTFHGLLTRARGPPIEGPPRPQRGSTSFLDTRF
::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RIVVQPPEEPRPPRRKPQTRGKTFHGLLTRARGPPIEGPPRPQRGSTSFLDTRF
300 310 320 330 340
446 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 14:47:05 2016 done: Mon Nov 7 14:47:07 2016
Total Scan time: 11.270 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]