Result of FASTA (omim) for
pFN21AE4078
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE4078, 412 aa
1>>>pF1KE4078 412 - 412 aa - 412 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.6569+/-0.00035; mu= 15.8452+/- 0.022
mean_var=111.9988+/-25.004, 0's: 0 Z-trim(115.9): 192 B-trim: 293 in 1/50
Lambda= 0.121190
statistics sampled from 26442 (26736) to 26442 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.68), E-opt: 0.2 (0.313), width: 16
Scan time: 8.060
The best scores are: opt bits E(85289)
NP_071322 (OMIM: 608071) F-box/WD repeat-containin ( 412) 2858 510.8 2.4e-144
NP_001310470 (OMIM: 608071) F-box/WD repeat-contai ( 325) 2279 409.5 6.1e-114
XP_016872059 (OMIM: 608071) PREDICTED: F-box/WD re ( 284) 1762 319.1 9e-87
XP_005270110 (OMIM: 608071) PREDICTED: F-box/WD re ( 436) 1762 319.2 1.2e-86
XP_011530390 (OMIM: 606278) PREDICTED: F-box/WD re ( 540) 210 48.0 6.8e-05
NP_001013433 (OMIM: 606278) F-box/WD repeat-contai ( 589) 210 48.0 7.2e-05
NP_060785 (OMIM: 606278) F-box/WD repeat-containin ( 627) 210 48.1 7.5e-05
XP_011530388 (OMIM: 606278) PREDICTED: F-box/WD re ( 679) 210 48.1 7.9e-05
XP_011530389 (OMIM: 606278) PREDICTED: F-box/WD re ( 679) 210 48.1 7.9e-05
XP_011530386 (OMIM: 606278) PREDICTED: F-box/WD re ( 707) 210 48.1 8.1e-05
NP_361014 (OMIM: 606278) F-box/WD repeat-containin ( 707) 210 48.1 8.1e-05
XP_011530385 (OMIM: 606278) PREDICTED: F-box/WD re ( 707) 210 48.1 8.1e-05
XP_011530387 (OMIM: 606278) PREDICTED: F-box/WD re ( 707) 210 48.1 8.1e-05
XP_016863851 (OMIM: 606278) PREDICTED: F-box/WD re ( 707) 210 48.1 8.1e-05
NP_001188493 (OMIM: 605961) pleiotropic regulator ( 505) 196 45.5 0.00035
NP_002660 (OMIM: 605961) pleiotropic regulator 1 i ( 514) 196 45.5 0.00036
NP_006089 (OMIM: 176981) receptor of activated pro ( 317) 190 44.3 0.00053
NP_001309195 (OMIM: 607795,615922) U4/U6 small nuc ( 279) 189 44.0 0.00055
NP_001309196 (OMIM: 607795,615922) U4/U6 small nuc ( 279) 189 44.0 0.00055
NP_001231855 (OMIM: 607795,615922) U4/U6 small nuc ( 521) 189 44.3 0.00084
NP_004688 (OMIM: 607795,615922) U4/U6 small nuclea ( 522) 189 44.3 0.00084
XP_016864369 (OMIM: 604734) PREDICTED: WD repeat-c ( 659) 182 43.2 0.0023
NP_001315 (OMIM: 600369) cleavage stimulation fact ( 431) 179 42.5 0.0025
NP_001028693 (OMIM: 600369) cleavage stimulation f ( 431) 179 42.5 0.0025
XP_011526902 (OMIM: 600369) PREDICTED: cleavage st ( 431) 179 42.5 0.0025
NP_001028694 (OMIM: 600369) cleavage stimulation f ( 431) 179 42.5 0.0025
XP_016863186 (OMIM: 609005) PREDICTED: WD repeat-c ( 982) 180 43.0 0.0039
XP_005262782 (OMIM: 609005) PREDICTED: WD repeat-c (1216) 180 43.1 0.0045
NP_851782 (OMIM: 609005) WD repeat-containing prot (1283) 180 43.1 0.0047
XP_011529884 (OMIM: 609005) PREDICTED: WD repeat-c (1290) 180 43.1 0.0047
XP_016863179 (OMIM: 609005) PREDICTED: WD repeat-c (1307) 180 43.1 0.0047
XP_016863178 (OMIM: 609005) PREDICTED: WD repeat-c (1307) 180 43.1 0.0047
XP_016863175 (OMIM: 609005) PREDICTED: WD repeat-c (1314) 180 43.2 0.0047
XP_016863176 (OMIM: 609005) PREDICTED: WD repeat-c (1314) 180 43.2 0.0047
XP_016863177 (OMIM: 609005) PREDICTED: WD repeat-c (1314) 180 43.2 0.0047
NP_733828 (OMIM: 609005) WD repeat-containing prot (1322) 180 43.2 0.0047
NP_001186104 (OMIM: 612190) target of rapamycin co ( 325) 167 40.2 0.0088
>>NP_071322 (OMIM: 608071) F-box/WD repeat-containing pr (412 aa)
initn: 2858 init1: 2858 opt: 2858 Z-score: 2712.5 bits: 510.8 E(85289): 2.4e-144
Smith-Waterman score: 2858; 100.0% identity (100.0% similar) in 412 aa overlap (1-412:1-412)
10 20 30 40 50 60
pF1KE4 MAAAAGEEEEEEEAARESAARPAAGPALWRLPEELLLLICSYLDMRALGRLAQVCRWLRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 MAAAAGEEEEEEEAARESAARPAAGPALWRLPEELLLLICSYLDMRALGRLAQVCRWLRR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 FTSCDLLWRRIARASLNSGFTRLGTDLMTSVPVKERVKVSQNWRLGRCREGILLKWRCSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 FTSCDLLWRRIARASLNSGFTRLGTDLMTSVPVKERVKVSQNWRLGRCREGILLKWRCSQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 MPWMQLEDDSLYISQANFILAYQFRPDGASLNRRPLGVFAGHDEDVCHFVLANSHIVSAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 MPWMQLEDDSLYISQANFILAYQFRPDGASLNRRPLGVFAGHDEDVCHFVLANSHIVSAG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 GDGKIGIHKIHSTFTVKYSAHEQEVNCVDCKGGIIVSGSRDRTAKVWPLASGRLGQCLHT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 GDGKIGIHKIHSTFTVKYSAHEQEVNCVDCKGGIIVSGSRDRTAKVWPLASGRLGQCLHT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 IQTEDRVWSIAISPLLSSFVTGTACCGHFSPLRIWDLNSGQLMTHLGSDFPPGAGVLDVM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 IQTEDRVWSIAISPLLSSFVTGTACCGHFSPLRIWDLNSGQLMTHLGSDFPPGAGVLDVM
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 YESPFTLLSCGYDTYVRYWDLRTSVRKCVMEWEEPHDSTLYCLQTDGNHLLATGSSYYGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 YESPFTLLSCGYDTYVRYWDLRTSVRKCVMEWEEPHDSTLYCLQTDGNHLLATGSSYYGV
310 320 330 340 350 360
370 380 390 400 410
pF1KE4 VRLWDRRQRACLHAFPLTSTPLSSPVYCLRLTTKHLYAALSYNLHVLDFQNP
::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 VRLWDRRQRACLHAFPLTSTPLSSPVYCLRLTTKHLYAALSYNLHVLDFQNP
370 380 390 400 410
>>NP_001310470 (OMIM: 608071) F-box/WD repeat-containing (325 aa)
initn: 2279 init1: 2279 opt: 2279 Z-score: 2166.6 bits: 409.5 E(85289): 6.1e-114
Smith-Waterman score: 2279; 100.0% identity (100.0% similar) in 325 aa overlap (88-412:1-325)
60 70 80 90 100 110
pF1KE4 LRRFTSCDLLWRRIARASLNSGFTRLGTDLMTSVPVKERVKVSQNWRLGRCREGILLKWR
::::::::::::::::::::::::::::::
NP_001 MTSVPVKERVKVSQNWRLGRCREGILLKWR
10 20 30
120 130 140 150 160 170
pF1KE4 CSQMPWMQLEDDSLYISQANFILAYQFRPDGASLNRRPLGVFAGHDEDVCHFVLANSHIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CSQMPWMQLEDDSLYISQANFILAYQFRPDGASLNRRPLGVFAGHDEDVCHFVLANSHIV
40 50 60 70 80 90
180 190 200 210 220 230
pF1KE4 SAGGDGKIGIHKIHSTFTVKYSAHEQEVNCVDCKGGIIVSGSRDRTAKVWPLASGRLGQC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SAGGDGKIGIHKIHSTFTVKYSAHEQEVNCVDCKGGIIVSGSRDRTAKVWPLASGRLGQC
100 110 120 130 140 150
240 250 260 270 280 290
pF1KE4 LHTIQTEDRVWSIAISPLLSSFVTGTACCGHFSPLRIWDLNSGQLMTHLGSDFPPGAGVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LHTIQTEDRVWSIAISPLLSSFVTGTACCGHFSPLRIWDLNSGQLMTHLGSDFPPGAGVL
160 170 180 190 200 210
300 310 320 330 340 350
pF1KE4 DVMYESPFTLLSCGYDTYVRYWDLRTSVRKCVMEWEEPHDSTLYCLQTDGNHLLATGSSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DVMYESPFTLLSCGYDTYVRYWDLRTSVRKCVMEWEEPHDSTLYCLQTDGNHLLATGSSY
220 230 240 250 260 270
360 370 380 390 400 410
pF1KE4 YGVVRLWDRRQRACLHAFPLTSTPLSSPVYCLRLTTKHLYAALSYNLHVLDFQNP
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YGVVRLWDRRQRACLHAFPLTSTPLSSPVYCLRLTTKHLYAALSYNLHVLDFQNP
280 290 300 310 320
>>XP_016872059 (OMIM: 608071) PREDICTED: F-box/WD repeat (284 aa)
initn: 1799 init1: 1758 opt: 1762 Z-score: 1678.8 bits: 319.1 E(85289): 9e-87
Smith-Waterman score: 1762; 95.3% identity (96.4% similar) in 275 aa overlap (1-275:1-270)
10 20 30 40 50 60
pF1KE4 MAAAAGEEEEEEEAARESAARPAAGPALWRLPEELLLLICSYLDMRALGRLAQVCRWLRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAAAAGEEEEEEEAARESAARPAAGPALWRLPEELLLLICSYLDMRALGRLAQVCRWLRR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 FTSCDLLWRRIARASLNSGFTRLGTDLMTSVPVKERVKVSQNWRLGRCREGILLKWRCSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FTSCDLLWRRIARASLNSGFTRLGTDLMTSVPVKERVKVSQNWRLGRCREGILLKWRCSQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 MPWMQLEDDSLYISQANFILAYQFRPDGASLNRRPLGVFAGHDEDVCHFVLANSHIVSAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MPWMQLEDDSLYISQANFILAYQFRPDGASLNRRPLGVFAGHDEDVCHFVLANSHIVSAG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 GDGKIGIHKIHSTFTVKYSAHEQEVNCVDCKGGIIVSGSRDRTAKVWPLASGRLGQCLHT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GDGKIGIHKIHSTFTVKYSAHEQEVNCVDCKGGIIVSGSRDRTAKVWPLASGRLGQCLHT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 IQTEDRVWSIAISPLLSSFVTGTACCGHFSPLRIWDLNSGQLMTHLGSDFPPGAGVLDVM
::::::::::::::::: ::.. . :::
XP_016 IQTEDRVWSIAISPLLS---TGASTVRDVT--RIWLKTSRGFKSNRFKF
250 260 270 280
310 320 330 340 350 360
pF1KE4 YESPFTLLSCGYDTYVRYWDLRTSVRKCVMEWEEPHDSTLYCLQTDGNHLLATGSSYYGV
>>XP_005270110 (OMIM: 608071) PREDICTED: F-box/WD repeat (436 aa)
initn: 1867 init1: 1758 opt: 1762 Z-score: 1676.5 bits: 319.2 E(85289): 1.2e-86
Smith-Waterman score: 2800; 94.5% identity (94.5% similar) in 436 aa overlap (1-412:1-436)
10 20 30 40 50 60
pF1KE4 MAAAAGEEEEEEEAARESAARPAAGPALWRLPEELLLLICSYLDMRALGRLAQVCRWLRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MAAAAGEEEEEEEAARESAARPAAGPALWRLPEELLLLICSYLDMRALGRLAQVCRWLRR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 FTSCDLLWRRIARASLNSGFTRLGTDLMTSVPVKERVKVSQNWRLGRCREGILLKWRCSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FTSCDLLWRRIARASLNSGFTRLGTDLMTSVPVKERVKVSQNWRLGRCREGILLKWRCSQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 MPWMQLEDDSLYISQANFILAYQFRPDGASLNRRPLGVFAGHDEDVCHFVLANSHIVSAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MPWMQLEDDSLYISQANFILAYQFRPDGASLNRRPLGVFAGHDEDVCHFVLANSHIVSAG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 GDGKIGIHKIHSTFTVKYSAHEQEVNCVDCKGGIIVSGSRDRTAKVWPLASGRLGQCLHT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GDGKIGIHKIHSTFTVKYSAHEQEVNCVDCKGGIIVSGSRDRTAKVWPLASGRLGQCLHT
190 200 210 220 230 240
250 260 270
pF1KE4 IQTEDRVWSIAISPLLS------------------------SFVTGTACCGHFSPLRIWD
::::::::::::::::: :::::::::::::::::::
XP_005 IQTEDRVWSIAISPLLSTGASTVRDVTRIWLKTSRGFKSNSSFVTGTACCGHFSPLRIWD
250 260 270 280 290 300
280 290 300 310 320 330
pF1KE4 LNSGQLMTHLGSDFPPGAGVLDVMYESPFTLLSCGYDTYVRYWDLRTSVRKCVMEWEEPH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LNSGQLMTHLGSDFPPGAGVLDVMYESPFTLLSCGYDTYVRYWDLRTSVRKCVMEWEEPH
310 320 330 340 350 360
340 350 360 370 380 390
pF1KE4 DSTLYCLQTDGNHLLATGSSYYGVVRLWDRRQRACLHAFPLTSTPLSSPVYCLRLTTKHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DSTLYCLQTDGNHLLATGSSYYGVVRLWDRRQRACLHAFPLTSTPLSSPVYCLRLTTKHL
370 380 390 400 410 420
400 410
pF1KE4 YAALSYNLHVLDFQNP
::::::::::::::::
XP_005 YAALSYNLHVLDFQNP
430
>>XP_011530390 (OMIM: 606278) PREDICTED: F-box/WD repeat (540 aa)
initn: 340 init1: 110 opt: 210 Z-score: 208.9 bits: 48.0 E(85289): 6.8e-05
Smith-Waterman score: 302; 28.1% identity (53.4% similar) in 352 aa overlap (31-375:117-410)
10 20 30 40 50 60
pF1KE4 MAAAAGEEEEEEEAARESAARPAAGPALWRLPEELLLLICSYLDMRALGRLAQVCRWLRR
::.:: : . :.:. . : . ::.::. :
XP_011 DELIDSCEPTQVKHMMQVIEPQFQRDFISLLPKELALYVLSFLEPKDLLQAAQTCRYWRI
90 100 110 120 130 140
70 80 90 100 110 120
pF1KE4 FTSCDLLWRRIARASLNSGFTRLGTDLMTSVPVKERVKVSQNWRLGRCREGILLKWRCSQ
.. .::::. . : : . .:.: :: . :.. .
XP_011 LAEDNLLWREKCKEE--------GID--EPLHIKRR-KV--------IKPGFI------H
150 160 170 180
130 140 150 160 170
pF1KE4 MPWMQLEDDSLYISQANFILAYQFRPDGASLNRRPLGVFAGHDEDV--CHFVLANSHIVS
:: : :: : . .. : . : : :. :::. : : . . ...:::
XP_011 SPW-----KSAYIRQHRIDTNWR-RGELKS----P-KVLKGHDDHVITC-LQFCGNRIVS
190 200 210 220
180 190 200 210 220 230
pF1KE4 AGGDGKIGIHKIHSTFTVK----YSAHEQEVNCVDCKGGIIVSGSRDRTAKVWPLASGRL
.. :. . :. :. : : .: : . . .::.::: ::: ::: ...
XP_011 GSDDNTL---KVWSAVTGKCLRTLVGHTGGVWSSQMRDNIIISGSTDRTLKVW---NAET
230 240 250 260 270 280
240 250 260 270 280 290
pF1KE4 GQCLHTIQTE-DRVWSIAISPLLSSFVTGTACCGHFSPLRIWDLNSGQLMTHLGSDFPPG
:.:.::. . . : . . . :.:. . . ::.::...:: . : .
XP_011 GECIHTLYGHTSTVRCMHLHE--KRVVSGS----RDATLRVWDIETGQCLHVLMGHV---
290 300 310 320 330
300 310 320 330 340 350
pF1KE4 AGVLDVMYESPFTLLSCGYDTYVRYWDLRTSVRKCVMEWEEPHDSTLYCLQTDGNHLLAT
:.: :.:.. ..: .:: .:. :: .: . : .. . : . .: :: :: :...
XP_011 AAVRCVQYDGR-RVVSGAYDFMVKVWDPETET--C-LHTLQGHTNRVYSLQFDGIHVVS-
340 350 360 370 380
360 370 380 390 400 410
pF1KE4 GSSYYGVVRLWDRRQRACLHAFPLTSTPLSSPVYCLRLTTKHLYAALSYNLHVLDFQNP
.: .:.:: . :.:..
XP_011 -GSLDTSIRVWDVETGNCIHTLTGHQSLTSGMELKDNILVSGNADSTVKIWDIKTGQCLQ
390 400 410 420 430 440
>>NP_001013433 (OMIM: 606278) F-box/WD repeat-containing (589 aa)
initn: 340 init1: 110 opt: 210 Z-score: 208.4 bits: 48.0 E(85289): 7.2e-05
Smith-Waterman score: 302; 28.1% identity (53.4% similar) in 352 aa overlap (31-375:166-459)
10 20 30 40 50 60
pF1KE4 MAAAAGEEEEEEEAARESAARPAAGPALWRLPEELLLLICSYLDMRALGRLAQVCRWLRR
::.:: : . :.:. . : . ::.::. :
NP_001 DELIDSCEPTQVKHMMQVIEPQFQRDFISLLPKELALYVLSFLEPKDLLQAAQTCRYWRI
140 150 160 170 180 190
70 80 90 100 110 120
pF1KE4 FTSCDLLWRRIARASLNSGFTRLGTDLMTSVPVKERVKVSQNWRLGRCREGILLKWRCSQ
.. .::::. . : : . .:.: :: . :.. .
NP_001 LAEDNLLWREKCKEE--------GID--EPLHIKRR-KV--------IKPGFI------H
200 210 220 230
130 140 150 160 170
pF1KE4 MPWMQLEDDSLYISQANFILAYQFRPDGASLNRRPLGVFAGHDEDV--CHFVLANSHIVS
:: : :: : . .. : . : : :. :::. : : . . ...:::
NP_001 SPW-----KSAYIRQHRIDTNWR-RGELKS----P-KVLKGHDDHVITC-LQFCGNRIVS
240 250 260 270
180 190 200 210 220 230
pF1KE4 AGGDGKIGIHKIHSTFTVK----YSAHEQEVNCVDCKGGIIVSGSRDRTAKVWPLASGRL
.. :. . :. :. : : .: : . . .::.::: ::: ::: ...
NP_001 GSDDNTL---KVWSAVTGKCLRTLVGHTGGVWSSQMRDNIIISGSTDRTLKVW---NAET
280 290 300 310 320 330
240 250 260 270 280 290
pF1KE4 GQCLHTIQTE-DRVWSIAISPLLSSFVTGTACCGHFSPLRIWDLNSGQLMTHLGSDFPPG
:.:.::. . . : . . . :.:. . . ::.::...:: . : .
NP_001 GECIHTLYGHTSTVRCMHLHE--KRVVSGS----RDATLRVWDIETGQCLHVLMGHV---
340 350 360 370 380
300 310 320 330 340 350
pF1KE4 AGVLDVMYESPFTLLSCGYDTYVRYWDLRTSVRKCVMEWEEPHDSTLYCLQTDGNHLLAT
:.: :.:.. ..: .:: .:. :: .: . : .. . : . .: :: :: :...
NP_001 AAVRCVQYDGR-RVVSGAYDFMVKVWDPETET--C-LHTLQGHTNRVYSLQFDGIHVVS-
390 400 410 420 430
360 370 380 390 400 410
pF1KE4 GSSYYGVVRLWDRRQRACLHAFPLTSTPLSSPVYCLRLTTKHLYAALSYNLHVLDFQNP
.: .:.:: . :.:..
NP_001 -GSLDTSIRVWDVETGNCIHTLTGHQSLTSGMELKDNILVSGNADSTVKIWDIKTGQCLQ
440 450 460 470 480 490
>>NP_060785 (OMIM: 606278) F-box/WD repeat-containing pr (627 aa)
initn: 340 init1: 110 opt: 210 Z-score: 208.1 bits: 48.1 E(85289): 7.5e-05
Smith-Waterman score: 302; 28.1% identity (53.4% similar) in 352 aa overlap (31-375:204-497)
10 20 30 40 50 60
pF1KE4 MAAAAGEEEEEEEAARESAARPAAGPALWRLPEELLLLICSYLDMRALGRLAQVCRWLRR
::.:: : . :.:. . : . ::.::. :
NP_060 DELIDSCEPTQVKHMMQVIEPQFQRDFISLLPKELALYVLSFLEPKDLLQAAQTCRYWRI
180 190 200 210 220 230
70 80 90 100 110 120
pF1KE4 FTSCDLLWRRIARASLNSGFTRLGTDLMTSVPVKERVKVSQNWRLGRCREGILLKWRCSQ
.. .::::. . : : . .:.: :: . :.. .
NP_060 LAEDNLLWREKCKEE--------GID--EPLHIKRR-KV--------IKPGFI------H
240 250 260
130 140 150 160 170
pF1KE4 MPWMQLEDDSLYISQANFILAYQFRPDGASLNRRPLGVFAGHDEDV--CHFVLANSHIVS
:: : :: : . .. : . : : :. :::. : : . . ...:::
NP_060 SPW-----KSAYIRQHRIDTNWR-RGELKS----P-KVLKGHDDHVITC-LQFCGNRIVS
270 280 290 300 310
180 190 200 210 220 230
pF1KE4 AGGDGKIGIHKIHSTFTVK----YSAHEQEVNCVDCKGGIIVSGSRDRTAKVWPLASGRL
.. :. . :. :. : : .: : . . .::.::: ::: ::: ...
NP_060 GSDDNTL---KVWSAVTGKCLRTLVGHTGGVWSSQMRDNIIISGSTDRTLKVW---NAET
320 330 340 350 360 370
240 250 260 270 280 290
pF1KE4 GQCLHTIQTE-DRVWSIAISPLLSSFVTGTACCGHFSPLRIWDLNSGQLMTHLGSDFPPG
:.:.::. . . : . . . :.:. . . ::.::...:: . : .
NP_060 GECIHTLYGHTSTVRCMHLHE--KRVVSGS----RDATLRVWDIETGQCLHVLMGHV---
380 390 400 410 420
300 310 320 330 340 350
pF1KE4 AGVLDVMYESPFTLLSCGYDTYVRYWDLRTSVRKCVMEWEEPHDSTLYCLQTDGNHLLAT
:.: :.:.. ..: .:: .:. :: .: . : .. . : . .: :: :: :...
NP_060 AAVRCVQYDGR-RVVSGAYDFMVKVWDPETET--C-LHTLQGHTNRVYSLQFDGIHVVS-
430 440 450 460 470
360 370 380 390 400 410
pF1KE4 GSSYYGVVRLWDRRQRACLHAFPLTSTPLSSPVYCLRLTTKHLYAALSYNLHVLDFQNP
.: .:.:: . :.:..
NP_060 -GSLDTSIRVWDVETGNCIHTLTGHQSLTSGMELKDNILVSGNADSTVKIWDIKTGQCLQ
480 490 500 510 520 530
>>XP_011530388 (OMIM: 606278) PREDICTED: F-box/WD repeat (679 aa)
initn: 340 init1: 110 opt: 210 Z-score: 207.6 bits: 48.1 E(85289): 7.9e-05
Smith-Waterman score: 302; 28.1% identity (53.4% similar) in 352 aa overlap (31-375:256-549)
10 20 30 40 50 60
pF1KE4 MAAAAGEEEEEEEAARESAARPAAGPALWRLPEELLLLICSYLDMRALGRLAQVCRWLRR
::.:: : . :.:. . : . ::.::. :
XP_011 DELIDSCEPTQVKHMMQVIEPQFQRDFISLLPKELALYVLSFLEPKDLLQAAQTCRYWRI
230 240 250 260 270 280
70 80 90 100 110 120
pF1KE4 FTSCDLLWRRIARASLNSGFTRLGTDLMTSVPVKERVKVSQNWRLGRCREGILLKWRCSQ
.. .::::. . : : . .:.: :: . :.. .
XP_011 LAEDNLLWREKCKEE--------GID--EPLHIKRR-KV--------IKPGFI------H
290 300 310 320
130 140 150 160 170
pF1KE4 MPWMQLEDDSLYISQANFILAYQFRPDGASLNRRPLGVFAGHDEDV--CHFVLANSHIVS
:: : :: : . .. : . : : :. :::. : : . . ...:::
XP_011 SPW-----KSAYIRQHRIDTNWR-RGELKS----P-KVLKGHDDHVITC-LQFCGNRIVS
330 340 350 360
180 190 200 210 220 230
pF1KE4 AGGDGKIGIHKIHSTFTVK----YSAHEQEVNCVDCKGGIIVSGSRDRTAKVWPLASGRL
.. :. . :. :. : : .: : . . .::.::: ::: ::: ...
XP_011 GSDDNTL---KVWSAVTGKCLRTLVGHTGGVWSSQMRDNIIISGSTDRTLKVW---NAET
370 380 390 400 410 420
240 250 260 270 280 290
pF1KE4 GQCLHTIQTE-DRVWSIAISPLLSSFVTGTACCGHFSPLRIWDLNSGQLMTHLGSDFPPG
:.:.::. . . : . . . :.:. . . ::.::...:: . : .
XP_011 GECIHTLYGHTSTVRCMHLHE--KRVVSGS----RDATLRVWDIETGQCLHVLMGHV---
430 440 450 460 470
300 310 320 330 340 350
pF1KE4 AGVLDVMYESPFTLLSCGYDTYVRYWDLRTSVRKCVMEWEEPHDSTLYCLQTDGNHLLAT
:.: :.:.. ..: .:: .:. :: .: . : .. . : . .: :: :: :...
XP_011 AAVRCVQYDGR-RVVSGAYDFMVKVWDPETET--C-LHTLQGHTNRVYSLQFDGIHVVS-
480 490 500 510 520
360 370 380 390 400 410
pF1KE4 GSSYYGVVRLWDRRQRACLHAFPLTSTPLSSPVYCLRLTTKHLYAALSYNLHVLDFQNP
.: .:.:: . :.:..
XP_011 -GSLDTSIRVWDVETGNCIHTLTGHQSLTSGMELKDNILVSGNADSTVKIWDIKTGQCLQ
530 540 550 560 570 580
>>XP_011530389 (OMIM: 606278) PREDICTED: F-box/WD repeat (679 aa)
initn: 340 init1: 110 opt: 210 Z-score: 207.6 bits: 48.1 E(85289): 7.9e-05
Smith-Waterman score: 302; 28.1% identity (53.4% similar) in 352 aa overlap (31-375:256-549)
10 20 30 40 50 60
pF1KE4 MAAAAGEEEEEEEAARESAARPAAGPALWRLPEELLLLICSYLDMRALGRLAQVCRWLRR
::.:: : . :.:. . : . ::.::. :
XP_011 DELIDSCEPTQVKHMMQVIEPQFQRDFISLLPKELALYVLSFLEPKDLLQAAQTCRYWRI
230 240 250 260 270 280
70 80 90 100 110 120
pF1KE4 FTSCDLLWRRIARASLNSGFTRLGTDLMTSVPVKERVKVSQNWRLGRCREGILLKWRCSQ
.. .::::. . : : . .:.: :: . :.. .
XP_011 LAEDNLLWREKCKEE--------GID--EPLHIKRR-KV--------IKPGFI------H
290 300 310 320
130 140 150 160 170
pF1KE4 MPWMQLEDDSLYISQANFILAYQFRPDGASLNRRPLGVFAGHDEDV--CHFVLANSHIVS
:: : :: : . .. : . : : :. :::. : : . . ...:::
XP_011 SPW-----KSAYIRQHRIDTNWR-RGELKS----P-KVLKGHDDHVITC-LQFCGNRIVS
330 340 350 360
180 190 200 210 220 230
pF1KE4 AGGDGKIGIHKIHSTFTVK----YSAHEQEVNCVDCKGGIIVSGSRDRTAKVWPLASGRL
.. :. . :. :. : : .: : . . .::.::: ::: ::: ...
XP_011 GSDDNTL---KVWSAVTGKCLRTLVGHTGGVWSSQMRDNIIISGSTDRTLKVW---NAET
370 380 390 400 410 420
240 250 260 270 280 290
pF1KE4 GQCLHTIQTE-DRVWSIAISPLLSSFVTGTACCGHFSPLRIWDLNSGQLMTHLGSDFPPG
:.:.::. . . : . . . :.:. . . ::.::...:: . : .
XP_011 GECIHTLYGHTSTVRCMHLHE--KRVVSGS----RDATLRVWDIETGQCLHVLMGHV---
430 440 450 460 470
300 310 320 330 340 350
pF1KE4 AGVLDVMYESPFTLLSCGYDTYVRYWDLRTSVRKCVMEWEEPHDSTLYCLQTDGNHLLAT
:.: :.:.. ..: .:: .:. :: .: . : .. . : . .: :: :: :...
XP_011 AAVRCVQYDGR-RVVSGAYDFMVKVWDPETET--C-LHTLQGHTNRVYSLQFDGIHVVS-
480 490 500 510 520
360 370 380 390 400 410
pF1KE4 GSSYYGVVRLWDRRQRACLHAFPLTSTPLSSPVYCLRLTTKHLYAALSYNLHVLDFQNP
.: .:.:: . :.:..
XP_011 -GSLDTSIRVWDVETGNCIHTLTGHQSLTSGMELKDNILVSGNADSTVKIWDIKTGQCLQ
530 540 550 560 570 580
>>XP_011530386 (OMIM: 606278) PREDICTED: F-box/WD repeat (707 aa)
initn: 340 init1: 110 opt: 210 Z-score: 207.4 bits: 48.1 E(85289): 8.1e-05
Smith-Waterman score: 302; 28.1% identity (53.4% similar) in 352 aa overlap (31-375:284-577)
10 20 30 40 50 60
pF1KE4 MAAAAGEEEEEEEAARESAARPAAGPALWRLPEELLLLICSYLDMRALGRLAQVCRWLRR
::.:: : . :.:. . : . ::.::. :
XP_011 DELIDSCEPTQVKHMMQVIEPQFQRDFISLLPKELALYVLSFLEPKDLLQAAQTCRYWRI
260 270 280 290 300 310
70 80 90 100 110 120
pF1KE4 FTSCDLLWRRIARASLNSGFTRLGTDLMTSVPVKERVKVSQNWRLGRCREGILLKWRCSQ
.. .::::. . : : . .:.: :: . :.. .
XP_011 LAEDNLLWREKCKEE--------GID--EPLHIKRR-KV--------IKPGFI------H
320 330 340
130 140 150 160 170
pF1KE4 MPWMQLEDDSLYISQANFILAYQFRPDGASLNRRPLGVFAGHDEDV--CHFVLANSHIVS
:: : :: : . .. : . : : :. :::. : : . . ...:::
XP_011 SPW-----KSAYIRQHRIDTNWR-RGELKS----P-KVLKGHDDHVITC-LQFCGNRIVS
350 360 370 380 390
180 190 200 210 220 230
pF1KE4 AGGDGKIGIHKIHSTFTVK----YSAHEQEVNCVDCKGGIIVSGSRDRTAKVWPLASGRL
.. :. . :. :. : : .: : . . .::.::: ::: ::: ...
XP_011 GSDDNTL---KVWSAVTGKCLRTLVGHTGGVWSSQMRDNIIISGSTDRTLKVW---NAET
400 410 420 430 440 450
240 250 260 270 280 290
pF1KE4 GQCLHTIQTE-DRVWSIAISPLLSSFVTGTACCGHFSPLRIWDLNSGQLMTHLGSDFPPG
:.:.::. . . : . . . :.:. . . ::.::...:: . : .
XP_011 GECIHTLYGHTSTVRCMHLHE--KRVVSGS----RDATLRVWDIETGQCLHVLMGHV---
460 470 480 490 500
300 310 320 330 340 350
pF1KE4 AGVLDVMYESPFTLLSCGYDTYVRYWDLRTSVRKCVMEWEEPHDSTLYCLQTDGNHLLAT
:.: :.:.. ..: .:: .:. :: .: . : .. . : . .: :: :: :...
XP_011 AAVRCVQYDGR-RVVSGAYDFMVKVWDPETET--C-LHTLQGHTNRVYSLQFDGIHVVS-
510 520 530 540 550
360 370 380 390 400 410
pF1KE4 GSSYYGVVRLWDRRQRACLHAFPLTSTPLSSPVYCLRLTTKHLYAALSYNLHVLDFQNP
.: .:.:: . :.:..
XP_011 -GSLDTSIRVWDVETGNCIHTLTGHQSLTSGMELKDNILVSGNADSTVKIWDIKTGQCLQ
560 570 580 590 600 610
412 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 03:58:47 2016 done: Sun Nov 6 03:58:49 2016
Total Scan time: 8.060 Total Display time: 0.050
Function used was FASTA [36.3.4 Apr, 2011]